IMP: Integrative Multi-species Prediction

Mus musculus

32 known processes

Cyp26c1

cytochrome P450, family 26, subfamily c, polypeptide 1

(Aliases: EG546726)

Entrez: 546726
Ensembl: ENSMUSG00000062432
UniProtKB: B2RXA7

Process Predictions
Disease Predictions

Cyp26c1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
fat soluble vitamin catabolic process	GO:0042363	1	0.998	Human
male meiosis	GO:0007140	37	0.775	Mouse
isoprenoid catabolic process	GO:0008300	2	0.745	Human
striated muscle tissue development	GO:0014706	293	0.554	Zebrafish Mouse
embryonic appendage morphogenesis	GO:0035113	126	0.443	Mouse
amine metabolic process	GO:0009308	45	0.414
male gamete generation	GO:0048232	285	0.374	Mouse
cellular response to lipid	GO:0071396	145	0.373	Mouse
renal system development	GO:0072001	225	0.361
regulation of cellular ketone metabolic process	GO:0010565	66	0.345
oxidation reduction process	GO:0055114	342	0.343	Human
spermatogenesis	GO:0007283	284	0.342	Mouse
positive regulation of skeletal muscle cell differentiation	GO:2001016	4	0.326	Mouse
muscle cell development	GO:0055001	133	0.318	Zebrafish
rhombomere development	GO:0021546	8	0.315	Zebrafish
cellular lipid catabolic process	GO:0044242	52	0.309	Human
cellular alcohol metabolic process	GO:0044107	3	0.302
cardiac muscle cell development	GO:0055013	39	0.297	Zebrafish
regulation of cellular amine metabolic process	GO:0033238	20	0.294
cardiac muscle cell differentiation	GO:0055007	69	0.293	Zebrafish
embryonic organ morphogenesis	GO:0048562	276	0.278
myotube differentiation	GO:0014902	105	0.277	Mouse
urogenital system development	GO:0001655	261	0.276
skeletal muscle organ development	GO:0060538	163	0.269	Mouse
cellular lipid metabolic process	GO:0044255	323	0.267	Human Zebrafish Mouse
stem cell differentiation	GO:0048863	268	0.265
regulation of tongue muscle cell differentiation	GO:2001035	2	0.264	Mouse
cellular amine metabolic process	GO:0044106	44	0.263
cation transport	GO:0006812	399	0.261
organelle fusion	GO:0048284	28	0.259
cellular amino acid metabolic process	GO:0006520	103	0.256
embryonic limb morphogenesis	GO:0030326	126	0.243	Mouse
muscle cell differentiation	GO:0042692	261	0.237	Zebrafish Mouse
sensory organ morphogenesis	GO:0090596	242	0.237	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.232
neural crest cell differentiation	GO:0014033	54	0.228
regulation of skeletal muscle fiber differentiation	GO:1902809	3	0.228	Mouse
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.228
stem cell development	GO:0048864	219	0.222
leukocyte differentiation	GO:0002521	342	0.219
nuclear division	GO:0000280	158	0.214	Mouse
cardiocyte differentiation	GO:0035051	87	0.213	Zebrafish
retinoid metabolic process	GO:0001523	24	0.213	Human Zebrafish Mouse
metal ion homeostasis	GO:0055065	189	0.210
camera type eye development	GO:0043010	266	0.206
regulation of cellular amino acid metabolic process	GO:0006521	5	0.202
regulation of secretion	GO:0051046	274	0.197
positive regulation of protein phosphorylation	GO:0001934	242	0.193
protein processing	GO:0016485	163	0.192
carboxylic acid catabolic process	GO:0046395	51	0.190	Human
mesenchyme development	GO:0060485	152	0.187
regulation of striated muscle cell differentiation	GO:0051153	81	0.185	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.183
chemotaxis	GO:0006935	247	0.183
striated muscle cell development	GO:0055002	125	0.181	Zebrafish
cellular response to acid chemical	GO:0071229	68	0.180	Mouse
peptidyl amino acid modification	GO:0018193	336	0.180
bmp signaling pathway	GO:0030509	93	0.176
epithelial tube morphogenesis	GO:0060562	303	0.175
myeloid leukocyte differentiation	GO:0002573	119	0.170
intracellular receptor signaling pathway	GO:0030522	74	0.169	Mouse
dna metabolic process	GO:0006259	303	0.167
blood vessel morphogenesis	GO:0048514	285	0.166
somitogenesis	GO:0001756	69	0.165
regulation of secretion by cell	GO:1903530	249	0.162
heart morphogenesis	GO:0003007	178	0.161
appendage morphogenesis	GO:0035107	149	0.160	Mouse
digestive system development	GO:0055123	200	0.158
cytokine production	GO:0001816	319	0.158
kidney epithelium development	GO:0072073	121	0.156
regulation of muscle tissue development	GO:1901861	97	0.154	Mouse
skin development	GO:0043588	220	0.153	Mouse
lipid catabolic process	GO:0016042	69	0.153	Human
segmentation	GO:0035282	93	0.152
mesenchymal cell differentiation	GO:0048762	107	0.151
pancreas development	GO:0031016	57	0.146
digestive tract morphogenesis	GO:0048546	147	0.146
regulation of body fluid levels	GO:0050878	162	0.143	Mouse
muscle tissue development	GO:0060537	308	0.143	Zebrafish Mouse
regulation of hormone levels	GO:0010817	211	0.142	Human Zebrafish Mouse
ossification	GO:0001503	216	0.141
rhombomere morphogenesis	GO:0021593	2	0.139	Zebrafish
apoptotic signaling pathway	GO:0097190	306	0.138
monocarboxylic acid catabolic process	GO:0072329	27	0.137	Human
response to extracellular stimulus	GO:0009991	127	0.135
organelle fission	GO:0048285	170	0.135	Mouse
myeloid cell differentiation	GO:0030099	233	0.134
retinal metabolic process	GO:0042574	5	0.134
fat cell differentiation	GO:0045444	160	0.133
regulation of apoptotic signaling pathway	GO:2001233	197	0.132
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.131
forebrain development	GO:0030900	302	0.129
epithelial cell proliferation	GO:0050673	174	0.128
protein secretion	GO:0009306	111	0.128
regulation of organ morphogenesis	GO:2000027	144	0.127
monocarboxylic acid metabolic process	GO:0032787	191	0.126	Human Zebrafish Mouse
renal tubule morphogenesis	GO:0061333	72	0.125
cellular response to dna damage stimulus	GO:0006974	207	0.125
positive regulation of tongue muscle cell differentiation	GO:2001037	2	0.124	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.124
t cell activation	GO:0042110	289	0.124
response to organonitrogen compound	GO:0010243	246	0.123
ear development	GO:0043583	200	0.122
cardiac cell development	GO:0055006	41	0.122	Zebrafish
meiotic nuclear division	GO:0007126	115	0.120	Mouse
positive regulation of protein modification process	GO:0031401	299	0.119
regulation of kinase activity	GO:0043549	249	0.119
regulation of response to wounding	GO:1903034	189	0.116
regulation of cytokine production	GO:0001817	266	0.116
nephron development	GO:0072006	109	0.116
sterol metabolic process	GO:0016125	58	0.115
mesenchymal cell development	GO:0014031	93	0.114
small molecule catabolic process	GO:0044282	71	0.114	Human
peptidyl tyrosine modification	GO:0018212	145	0.113
keratinocyte differentiation	GO:0030216	48	0.113	Mouse
cellular ketone metabolic process	GO:0042180	84	0.113
regulation of leukocyte differentiation	GO:1902105	159	0.112
production of molecular mediator of immune response	GO:0002440	103	0.110
respiratory system development	GO:0060541	190	0.110
protein maturation	GO:0051604	176	0.109
regulation of cellular catabolic process	GO:0031329	242	0.109
cellular ion homeostasis	GO:0006873	165	0.105
regionalization	GO:0003002	337	0.105
cellular response to external stimulus	GO:0071496	88	0.105
diterpenoid metabolic process	GO:0016101	24	0.104	Human Zebrafish Mouse
sensory perception	GO:0007600	245	0.103
nephron epithelium morphogenesis	GO:0072088	68	0.103
positive regulation of cell development	GO:0010720	237	0.102
positive regulation of programmed cell death	GO:0043068	218	0.101
ear morphogenesis	GO:0042471	118	0.100
connective tissue development	GO:0061448	179	0.099
regulation of myotube differentiation	GO:0010830	62	0.099	Mouse
cation homeostasis	GO:0055080	212	0.099
positive regulation of muscle tissue development	GO:1901863	32	0.099	Mouse
regulation of defense response	GO:0031347	233	0.099
limb development	GO:0060173	166	0.098	Mouse
regulation of transferase activity	GO:0051338	263	0.098
regulation of protein localization	GO:0032880	231	0.098
ureteric bud morphogenesis	GO:0060675	62	0.097
inner ear morphogenesis	GO:0042472	101	0.097
nephron epithelium development	GO:0072009	92	0.096
positive regulation of apoptotic process	GO:0043065	217	0.096
positive regulation of striated muscle cell differentiation	GO:0051155	35	0.096	Mouse
metanephros development	GO:0001656	79	0.096
circulatory system process	GO:0003013	197	0.095
homeostasis of number of cells	GO:0048872	210	0.095
leukocyte proliferation	GO:0070661	172	0.094
establishment of skin barrier	GO:0061436	14	0.094	Mouse
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.093
multicellular organismal water homeostasis	GO:0050891	23	0.091	Mouse
regulation of water loss via skin	GO:0033561	16	0.091	Mouse
regulation of lymphocyte activation	GO:0051249	240	0.090
developmental maturation	GO:0021700	193	0.090
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.090
positive regulation of cell migration	GO:0030335	109	0.089
immune effector process	GO:0002252	321	0.089
regulation of cell motility	GO:2000145	236	0.089
cellular response to nutrient levels	GO:0031669	64	0.089
epidermis development	GO:0008544	187	0.089	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.088
negative regulation of cell proliferation	GO:0008285	296	0.087
cytokine secretion	GO:0050663	72	0.086
chromatin organization	GO:0006325	206	0.086
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.085
mesonephric epithelium development	GO:0072163	94	0.085
cell type specific apoptotic process	GO:0097285	268	0.085
glial cell differentiation	GO:0010001	131	0.085
somite development	GO:0061053	81	0.083
nephron tubule morphogenesis	GO:0072078	68	0.082
regulation of cellular protein catabolic process	GO:1903362	61	0.082
response to nutrient levels	GO:0031667	109	0.082
divalent inorganic cation homeostasis	GO:0072507	138	0.081
response to retinoic acid	GO:0032526	56	0.081	Mouse
hormone secretion	GO:0046879	128	0.080
regulation of protein transport	GO:0051223	163	0.080
hindbrain development	GO:0030902	128	0.079	Zebrafish
neuron projection guidance	GO:0097485	141	0.079
digestive tract development	GO:0048565	190	0.079
regulation of inflammatory response	GO:0050727	147	0.078
tongue development	GO:0043586	18	0.078	Mouse
skeletal system development	GO:0001501	356	0.078
regulation of protein secretion	GO:0050708	82	0.078
t cell differentiation	GO:0030217	174	0.077
cellular response to vitamin	GO:0071295	2	0.076
cellular response to cytokine stimulus	GO:0071345	189	0.075
nephron tubule development	GO:0072080	84	0.074
positive regulation of cell death	GO:0010942	224	0.073
negative regulation of molecular function	GO:0044092	258	0.073
regulation of cellular response to stress	GO:0080135	159	0.073
gastrulation	GO:0007369	116	0.072
cellular response to extracellular stimulus	GO:0031668	81	0.072
atrial cardiac muscle cell development	GO:0055014	2	0.072	Zebrafish
canonical wnt signaling pathway	GO:0060070	130	0.071
mesonephros development	GO:0001823	97	0.070
negative regulation of cellular protein metabolic process	GO:0032269	247	0.070
atrial cardiac muscle cell differentiation	GO:0055011	2	0.069	Zebrafish
regulation of ossification	GO:0030278	112	0.069
transmission of nerve impulse	GO:0019226	76	0.069
cell fate commitment	GO:0045165	210	0.068	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.068
synaptic transmission	GO:0007268	329	0.068
small molecule biosynthetic process	GO:0044283	132	0.068
positive regulation of proteolysis	GO:0045862	85	0.067
gonad development	GO:0008406	141	0.066
cell maturation	GO:0048469	127	0.066
regulation of cell migration	GO:0030334	219	0.066
reactive oxygen species metabolic process	GO:0072593	84	0.066
cardiac muscle tissue development	GO:0048738	130	0.066	Zebrafish
response to growth factor	GO:0070848	198	0.065
neuron migration	GO:0001764	122	0.065
regulation of anatomical structure size	GO:0090066	178	0.064
lymphocyte differentiation	GO:0030098	242	0.064
mesoderm development	GO:0007498	100	0.064
modification dependent macromolecule catabolic process	GO:0043632	133	0.064
regulation of peptidase activity	GO:0052547	96	0.064
mesoderm formation	GO:0001707	62	0.063
regulation of cell cycle	GO:0051726	281	0.063
organic hydroxy compound biosynthetic process	GO:1901617	77	0.063
peptide transport	GO:0015833	133	0.063
b cell activation	GO:0042113	161	0.063
positive regulation of myotube differentiation	GO:0010831	24	0.063	Mouse
cell adhesion	GO:0007155	329	0.062
amide transport	GO:0042886	138	0.062
angiogenesis	GO:0001525	201	0.061
negative regulation of phosphorus metabolic process	GO:0010563	184	0.061
endocrine system development	GO:0035270	98	0.061
cellular response to organonitrogen compound	GO:0071417	145	0.061
response to acid chemical	GO:0001101	111	0.061	Mouse
regulation of cell projection organization	GO:0031344	206	0.060
anatomical structure homeostasis	GO:0060249	145	0.060
negative regulation of immune system process	GO:0002683	209	0.060
ubiquitin dependent protein catabolic process	GO:0006511	129	0.060
positive regulation of striated muscle tissue development	GO:0045844	31	0.059	Mouse
regulation of bmp signaling pathway	GO:0030510	60	0.059
modification dependent protein catabolic process	GO:0019941	133	0.059
nucleoside phosphate metabolic process	GO:0006753	338	0.059
protein modification by small protein conjugation	GO:0032446	187	0.059
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.059
gland development	GO:0048732	330	0.059
regulation of proteolysis	GO:0030162	164	0.058
respiratory tube development	GO:0030323	167	0.058
telencephalon development	GO:0021537	186	0.058
purine containing compound metabolic process	GO:0072521	311	0.058
regulation of protein kinase activity	GO:0045859	232	0.058
cation transmembrane transport	GO:0098655	266	0.058
regulation of nucleotide metabolic process	GO:0006140	169	0.057
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.057
regulation of interferon gamma production	GO:0032649	57	0.057
dna repair	GO:0006281	107	0.057
isoprenoid metabolic process	GO:0006720	29	0.057	Human Zebrafish Mouse
nephron morphogenesis	GO:0072028	69	0.057
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.057
embryonic heart tube development	GO:0035050	65	0.057
paraxial mesodermal cell fate commitment	GO:0048343	2	0.057
response to lipopolysaccharide	GO:0032496	128	0.056
negative regulation of nervous system development	GO:0051961	156	0.056
protein ubiquitination	GO:0016567	171	0.056
regulation of organelle organization	GO:0033043	289	0.056
regulation of membrane potential	GO:0042391	192	0.056
blood vessel remodeling	GO:0001974	33	0.056
mesonephric tubule morphogenesis	GO:0072171	63	0.056
g protein coupled receptor signaling pathway	GO:0007186	243	0.056
brain morphogenesis	GO:0048854	32	0.056
dna recombination	GO:0006310	92	0.055
lipid biosynthetic process	GO:0008610	179	0.055
carbohydrate derivative biosynthetic process	GO:1901137	183	0.055
response to molecule of bacterial origin	GO:0002237	143	0.054
protein modification by small protein conjugation or removal	GO:0070647	207	0.054
paraxial mesodermal cell differentiation	GO:0048342	2	0.054
defense response to other organism	GO:0098542	197	0.054
muscle system process	GO:0003012	141	0.053
regulation of osteoblast differentiation	GO:0045667	67	0.053
regulation of production of molecular mediator of immune response	GO:0002700	65	0.053
extracellular matrix organization	GO:0030198	147	0.053
regulation of cell activation	GO:0050865	289	0.052
methylation	GO:0032259	134	0.052
regulation of tube size	GO:0035150	57	0.052
regulation of ion transport	GO:0043269	215	0.052
multicellular organismal signaling	GO:0035637	91	0.051
cellular response to molecule of bacterial origin	GO:0071219	83	0.051
nitrogen compound transport	GO:0071705	271	0.051
organic hydroxy compound metabolic process	GO:1901615	203	0.051
regulation of neuron apoptotic process	GO:0043523	122	0.051
nucleotide metabolic process	GO:0009117	332	0.051
regulation of adaptive immune response	GO:0002819	90	0.051
hormone metabolic process	GO:0042445	86	0.051	Human Zebrafish Mouse
kidney development	GO:0001822	213	0.050
regulation of homeostatic process	GO:0032844	182	0.050
cellular response to growth factor stimulus	GO:0071363	197	0.050
cerebral cortex development	GO:0021987	86	0.050
positive regulation of cellular catabolic process	GO:0031331	148	0.050
blood circulation	GO:0008015	195	0.049
molting cycle	GO:0042303	90	0.049
hematopoietic progenitor cell differentiation	GO:0002244	143	0.049
transmembrane transport	GO:0055085	412	0.049
regulation of epithelial cell proliferation	GO:0050678	141	0.049
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.049
ameboidal type cell migration	GO:0001667	128	0.049
mapk cascade	GO:0000165	281	0.049
regulation of chemotaxis	GO:0050920	53	0.048
antimicrobial peptide production	GO:0002775	2	0.048
negative regulation of phosphate metabolic process	GO:0045936	184	0.048
cytokine metabolic process	GO:0042107	71	0.048
regulation of mitotic cell cycle	GO:0007346	126	0.048
membrane organization	GO:0061024	245	0.048
hair follicle development	GO:0001942	85	0.048
steroid metabolic process	GO:0008202	119	0.048
cellular calcium ion homeostasis	GO:0006874	119	0.048
positive regulation of hydrolase activity	GO:0051345	148	0.047
ureteric bud development	GO:0001657	94	0.047
ras protein signal transduction	GO:0007265	77	0.047
positive regulation of secretion by cell	GO:1903532	114	0.047
positive regulation of neuron differentiation	GO:0045666	141	0.047
immune response regulating signaling pathway	GO:0002764	125	0.047
organ growth	GO:0035265	117	0.047
regulation of embryonic development	GO:0045995	71	0.046
regulation of protein maturation	GO:1903317	96	0.046
cardiac chamber morphogenesis	GO:0003206	93	0.046
nephrogenic mesenchyme development	GO:0072076	3	0.046
purine ribonucleotide metabolic process	GO:0009150	290	0.046
positive regulation of cell motility	GO:2000147	116	0.046
regulation of lymphocyte differentiation	GO:0045619	107	0.046
leukocyte activation involved in immune response	GO:0002366	126	0.046
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.046
morphogenesis of embryonic epithelium	GO:0016331	159	0.045
inorganic ion transmembrane transport	GO:0098660	234	0.045
positive regulation of response to wounding	GO:1903036	66	0.045
cellular metal ion homeostasis	GO:0006875	151	0.045
ribonucleotide metabolic process	GO:0009259	291	0.045
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.045
intrinsic apoptotic signaling pathway	GO:0097193	132	0.045
maintenance of location	GO:0051235	89	0.045
metencephalon development	GO:0022037	89	0.045
cardiac ventricle development	GO:0003231	83	0.045
bone development	GO:0060348	120	0.044
regulation of hydrolase activity	GO:0051336	246	0.044
tissue remodeling	GO:0048771	102	0.044
alcohol metabolic process	GO:0006066	116	0.044
limb morphogenesis	GO:0035108	149	0.044	Mouse
notch signaling pathway	GO:0007219	71	0.044
cellular protein catabolic process	GO:0044257	155	0.044
stress activated protein kinase signaling cascade	GO:0031098	81	0.044
organonitrogen compound biosynthetic process	GO:1901566	192	0.044
interferon gamma production	GO:0032609	67	0.043
skeletal muscle cell differentiation	GO:0035914	66	0.043	Mouse
positive regulation of cytokine secretion	GO:0050715	41	0.043
cellular macromolecule catabolic process	GO:0044265	206	0.043
regulation of cytokine secretion	GO:0050707	61	0.043
activation of immune response	GO:0002253	138	0.042
rho protein signal transduction	GO:0007266	32	0.042
chondrocyte differentiation	GO:0002062	72	0.042
negative regulation of synapse assembly	GO:0051964	3	0.042
regulation of fat cell differentiation	GO:0045598	81	0.042
central nervous system neuron differentiation	GO:0021953	162	0.041
multicellular organismal homeostasis	GO:0048871	164	0.041
negative regulation of cellular amine metabolic process	GO:0033239	1	0.041
regulation of t cell activation	GO:0050863	170	0.041
jnk cascade	GO:0007254	72	0.041
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.041
positive regulation of mapk cascade	GO:0043410	170	0.041
positive regulation of growth	GO:0045927	104	0.041
negative regulation of retinoic acid receptor signaling pathway	GO:0048387	5	0.041	Mouse
bone morphogenesis	GO:0060349	78	0.040
positive regulation of lymphocyte activation	GO:0051251	140	0.040
wound healing	GO:0042060	157	0.040
negative regulation of cytokine production	GO:0001818	84	0.040
multicellular organism growth	GO:0035264	161	0.040
mesonephric tubule development	GO:0072164	94	0.040
cell differentiation in hindbrain	GO:0021533	24	0.040
extracellular structure organization	GO:0043062	148	0.040
somatic stem cell maintenance	GO:0035019	47	0.040
muscle contraction	GO:0006936	101	0.040
sequestering of metal ion	GO:0051238	19	0.040
regulation of lipid metabolic process	GO:0019216	118	0.040
regulation of peptide transport	GO:0090087	91	0.039
lung morphogenesis	GO:0060425	50	0.039
wnt signaling pathway	GO:0016055	188	0.039
macromolecule catabolic process	GO:0009057	281	0.039
positive regulation of cell activation	GO:0050867	158	0.039
ribose phosphate metabolic process	GO:0019693	291	0.039
cell activation involved in immune response	GO:0002263	126	0.039
cellular aldehyde metabolic process	GO:0006081	12	0.039
mitotic cell cycle	GO:0000278	195	0.039
mitotic cell cycle process	GO:1903047	159	0.039
peptide secretion	GO:0002790	114	0.039
sterol biosynthetic process	GO:0016126	17	0.039
vitamin catabolic process	GO:0009111	1	0.039	Human
cellular response to biotic stimulus	GO:0071216	92	0.038
regulation of interleukin 8 production	GO:0032677	3	0.038
organic cyclic compound catabolic process	GO:1901361	295	0.038
cytoplasmic transport	GO:0016482	234	0.038
response to vitamin a	GO:0033189	1	0.038
response to starvation	GO:0042594	65	0.038
positive regulation of cell cycle	GO:0045787	92	0.038
syncytium formation by plasma membrane fusion	GO:0000768	42	0.038
cellular response to hormone stimulus	GO:0032870	150	0.037
negative regulation of intracellular signal transduction	GO:1902532	167	0.037
innate immune response	GO:0045087	157	0.037
female sex differentiation	GO:0046660	84	0.037
skeletal system morphogenesis	GO:0048705	203	0.037
regulation of mapk cascade	GO:0043408	248	0.037
regulation of hormone secretion	GO:0046883	88	0.037
response to inorganic substance	GO:0010035	96	0.036
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.036
posttranscriptional regulation of gene expression	GO:0010608	155	0.036
lateral inhibition	GO:0046331	1	0.036
negative regulation of growth	GO:0045926	99	0.036
cytokine biosynthetic process	GO:0042089	68	0.036
microtubule based process	GO:0007017	236	0.036
organophosphate biosynthetic process	GO:0090407	122	0.036
formation of primary germ layer	GO:0001704	77	0.036
positive regulation of bmp signaling pathway	GO:0030513	23	0.036
immune response activating signal transduction	GO:0002757	116	0.036
tissue homeostasis	GO:0001894	115	0.036
positive regulation of defense response	GO:0031349	124	0.036
regulation of protein catabolic process	GO:0042176	108	0.036
lymphocyte mediated immunity	GO:0002449	139	0.035
telencephalon cell migration	GO:0022029	55	0.035
positive regulation of production of molecular mediator of immune response	GO:0002702	45	0.035
divalent inorganic cation transport	GO:0072511	178	0.035
positive regulation of epithelial cell proliferation	GO:0050679	68	0.035
protein kinase b signaling	GO:0043491	74	0.035
embryonic epithelial tube formation	GO:0001838	130	0.035
small gtpase mediated signal transduction	GO:0007264	97	0.035
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.035
establishment of protein localization to organelle	GO:0072594	118	0.035
response to organic cyclic compound	GO:0014070	198	0.035
regulation of cytokine biosynthetic process	GO:0042035	59	0.035
pallium development	GO:0021543	120	0.035
terpenoid metabolic process	GO:0006721	25	0.034	Human Zebrafish Mouse
response to radiation	GO:0009314	165	0.034
neuron death	GO:0070997	154	0.034
hair cycle	GO:0042633	90	0.034
positive regulation of leukocyte differentiation	GO:1902107	86	0.034
macromolecule methylation	GO:0043414	120	0.034
positive regulation of innate immune response	GO:0045089	80	0.034
neural crest cell development	GO:0014032	48	0.034
forebrain cell migration	GO:0021885	58	0.034
negative regulation of cell activation	GO:0050866	111	0.034
positive regulation of peptidase activity	GO:0010952	49	0.034
neural precursor cell proliferation	GO:0061351	121	0.034
regulation of cell growth	GO:0001558	91	0.034
eye photoreceptor cell differentiation	GO:0001754	41	0.034
multi multicellular organism process	GO:0044706	109	0.034
myeloid leukocyte activation	GO:0002274	83	0.033
regulation of skeletal muscle cell differentiation	GO:2001014	11	0.033	Mouse
bone mineralization	GO:0030282	54	0.033
cellular chemical homeostasis	GO:0055082	215	0.033
peptidyl serine phosphorylation	GO:0018105	74	0.033
neuromuscular process	GO:0050905	99	0.033
negative regulation of response to wounding	GO:1903035	77	0.033
odontogenesis	GO:0042476	78	0.033
regulation of neuron death	GO:1901214	134	0.033
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.033
vascular process in circulatory system	GO:0003018	62	0.033
antibacterial peptide biosynthetic process	GO:0002780	2	0.032
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.032
lymphocyte activation involved in immune response	GO:0002285	93	0.032
cardiac muscle tissue morphogenesis	GO:0055008	44	0.032
aromatic compound catabolic process	GO:0019439	286	0.032
stem cell maintenance	GO:0019827	130	0.032
ion transmembrane transport	GO:0034220	361	0.032
negative regulation of proteolysis	GO:0045861	74	0.032
negative regulation of cell cycle	GO:0045786	123	0.032
epithelial tube formation	GO:0072175	130	0.032
sequestering of calcium ion	GO:0051208	18	0.032
positive regulation of immune effector process	GO:0002699	107	0.032
regulation of innate immune response	GO:0045088	91	0.031
regulation of vesicle mediated transport	GO:0060627	139	0.031
endoderm development	GO:0007492	45	0.031
microtubule cytoskeleton organization	GO:0000226	157	0.031
action potential	GO:0001508	78	0.031
regulation of system process	GO:0044057	200	0.031
negative regulation of secretion	GO:0051048	61	0.031
regulation of morphogenesis of a branching structure	GO:0060688	53	0.031
cell fate determination	GO:0001709	32	0.031	Mouse
regulation of intracellular transport	GO:0032386	159	0.031
positive regulation of transferase activity	GO:0051347	167	0.031
embryonic heart tube morphogenesis	GO:0003143	51	0.031
epithelial cell development	GO:0002064	159	0.031
embryonic placenta development	GO:0001892	98	0.030
epithelial to mesenchymal transition	GO:0001837	47	0.030
diencephalon development	GO:0021536	63	0.030
somatic diversification of immune receptors	GO:0002200	53	0.030
cognition	GO:0050890	149	0.030
steroid biosynthetic process	GO:0006694	47	0.030
odontogenesis of dentin containing tooth	GO:0042475	66	0.030
blastocyst development	GO:0001824	80	0.030
anion transport	GO:0006820	177	0.030
neuron projection extension	GO:1990138	64	0.030
appendage development	GO:0048736	166	0.030	Mouse

Cyp26c1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.044
nervous system disease	DOID:863	0.044
cancer	DOID:162	0.031
disease of cellular proliferation	DOID:14566	0.031
organ system cancer	DOID:0050686	0.031

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