Mus musculus

111 known processes

Nphs1

nephrosis 1 homolog, nephrin (human)

(Aliases: NephrinB,nephrin)

Nphs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.771
inorganic cation transmembrane transportGO:00986622070.290
transmembrane transportGO:00550854120.197
cation transmembrane transportGO:00986552660.174
regulation of ion transportGO:00432692150.168
cation transportGO:00068123990.154
locomotory behaviorGO:00076261950.136
renal system developmentGO:00720012250.132
Human Zebrafish Mouse Fly
regulation of transmembrane transportGO:00347621280.123
sodium ion transmembrane transportGO:0035725490.102
anion transportGO:00068201770.099
multicellular organismal signalingGO:0035637910.096
cellular amino acid metabolic processGO:00065201030.091
synaptic transmissionGO:00072683290.089
ribonucleoside catabolic processGO:00424542060.087
inorganic ion transmembrane transportGO:00986602340.085
regulation of transporter activityGO:0032409570.081
organic cyclic compound catabolic processGO:19013612950.080
purine nucleotide catabolic processGO:00061952110.078
ribonucleoside triphosphate catabolic processGO:00092031990.077
maintenance of locationGO:0051235890.075
purine ribonucleotide catabolic processGO:00091542080.075
negative regulation of cellular amino acid metabolic processGO:004576300.073
nucleoside triphosphate metabolic processGO:00091412300.072
protein modification by small protein conjugation or removalGO:00706472070.072
sensory organ morphogenesisGO:00905962420.072
Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.070
lymphocyte proliferationGO:00466511640.070
positive regulation of cell deathGO:00109422240.069
cellular nitrogen compound catabolic processGO:00442702800.068
nucleoside phosphate catabolic processGO:19012922220.068
negative regulation of cellular amine metabolic processGO:003323910.067
leukocyte proliferationGO:00706611720.067
nucleobase containing small molecule metabolic processGO:00550863520.065
ribonucleotide catabolic processGO:00092612080.064
glycosyl compound catabolic processGO:19016582060.064
action potentialGO:0001508780.064
immune effector processGO:00022523210.063
glycosyl compound metabolic processGO:19016572460.060
positive regulation of lymphocyte activationGO:00512511400.060
organic acid transportGO:00158491010.060
amine metabolic processGO:0009308450.058
defense response to virusGO:0051607680.058
regulation of cellular amino acid metabolic processGO:000652150.057
cellular chemical homeostasisGO:00550822150.057
myotube differentiationGO:00149021050.056
regulation of mitotic cell cycleGO:00073461260.056
regulation of membrane potentialGO:00423911920.055
purine ribonucleotide metabolic processGO:00091502900.054
regulation of cell projection organizationGO:00313442060.053
aromatic compound catabolic processGO:00194392860.052
organonitrogen compound catabolic processGO:19015652640.051
regulation of cellular ketone metabolic processGO:0010565660.050
regulation of cell cycle processGO:00105641600.050
sodium ion transportGO:0006814730.048
cell type specific apoptotic processGO:00972852680.047
learningGO:0007612980.047
positive regulation of programmed cell deathGO:00430682180.046
camera type eye developmentGO:00430102660.044
purine ribonucleoside catabolic processGO:00461302050.044
cellular protein catabolic processGO:00442571550.044
lymphocyte differentiationGO:00300982420.043
negative regulation of protein metabolic processGO:00512482820.043
Mouse
axonogenesisGO:00074092740.042
regulation of cell cycleGO:00517262810.042
regionalizationGO:00030023370.042
urogenital system developmentGO:00016552610.041
Human Zebrafish Mouse Fly
nucleoside metabolic processGO:00091162460.041
protein ubiquitinationGO:00165671710.041
regulation of sodium ion transmembrane transporter activityGO:200064990.040
glucose homeostasisGO:00425931280.040
ossificationGO:00015032160.040
purine ribonucleoside metabolic processGO:00461282410.039
protein modification by small protein conjugationGO:00324461870.039
positive regulation of nervous system developmentGO:00519622210.039
regulation of cellular catabolic processGO:00313292420.039
regulation of striated muscle cell differentiationGO:0051153810.039
mitotic cell cycleGO:00002781950.038
leukocyte differentiationGO:00025213420.038
ribonucleoside metabolic processGO:00091192450.038
regulation of cytoskeleton organizationGO:00514931220.037
negative regulation of cell cycleGO:00457861230.037
tube formationGO:00351481400.036
heterocycle catabolic processGO:00467002800.036
endomembrane system organizationGO:00102561470.036
carbohydrate derivative catabolic processGO:19011362310.036
regulation of organelle organizationGO:00330432890.035
divalent inorganic cation transportGO:00725111780.035
positive regulation of cellular catabolic processGO:00313311480.035
mitochondrion organizationGO:00070051340.035
guanosine containing compound catabolic processGO:19010691440.034
positive regulation of cell developmentGO:00107202370.034
nucleoside phosphate metabolic processGO:00067533380.034
negative regulation of oxidative phosphorylation uncoupler activityGO:200027620.034
actin filament organizationGO:00070151130.033
nephron developmentGO:00720061090.033
Human Zebrafish Mouse
rho protein signal transductionGO:0007266320.033
response to radiationGO:00093141650.033
regulation of protein localizationGO:00328802310.032
positive regulation of apoptotic processGO:00430652170.032
cell divisionGO:00513011200.032
purine nucleotide metabolic processGO:00061633020.032
purine ribonucleoside triphosphate catabolic processGO:00092071990.032
regulation of cellular amine metabolic processGO:0033238200.031
single organismal cell cell adhesionGO:00163371310.031
Mouse
nuclear divisionGO:00002801580.031
negative regulation of cellular component organizationGO:00511291940.031
defense response to other organismGO:00985421970.031
response to light stimulusGO:00094161350.030
regulation of synaptic plasticityGO:0048167870.030
organophosphate catabolic processGO:00464342320.030
cellular ketone metabolic processGO:0042180840.030
regulation of homeostatic processGO:00328441820.030
appendage morphogenesisGO:00351071490.030
organic anion transportGO:00157111370.029
purine nucleoside triphosphate metabolic processGO:00091442260.029
learning or memoryGO:00076111480.029
regulation of ion transmembrane transportGO:00347651190.029
positive regulation of purine nucleotide catabolic processGO:0033123880.028
intracellular protein transportGO:00068862040.028
regulation of actin filament based processGO:0032970990.028
ribose phosphate metabolic processGO:00196932910.027
negative regulation of cell proliferationGO:00082852960.027
response to growth factorGO:00708481980.027
g protein coupled receptor signaling pathwayGO:00071862430.027
forebrain developmentGO:00309003020.027
organelle localizationGO:00516401790.026
cellular response to growth factor stimulusGO:00713631970.026
regulation of actin cytoskeleton organizationGO:0032956840.026
neuronal action potentialGO:0019228540.026
cerebral cortex developmentGO:0021987860.026
neuron deathGO:00709971540.025
hematopoietic progenitor cell differentiationGO:00022441430.025
cellular homeostasisGO:00197252400.025
chemotaxisGO:00069352470.025
carbohydrate homeostasisGO:00335001280.025
ribonucleotide metabolic processGO:00092592910.024
cellular response to monosaccharide stimulusGO:0071326470.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.024
organic hydroxy compound metabolic processGO:19016152030.024
regulation of ossificationGO:00302781120.024
negative regulation of nervous system developmentGO:00519611560.024
ubiquitin dependent protein catabolic processGO:00065111290.024
anatomical structure homeostasisGO:00602491450.024
cytoplasmic transportGO:00164822340.023
cognitionGO:00508901490.023
positive regulation of lymphocyte differentiationGO:0045621610.023
establishment of organelle localizationGO:00516561220.023
regulation of mitotic cell cycle phase transitionGO:1901990730.023
nucleotide metabolic processGO:00091173320.023
response to peptideGO:19016521360.023
purine nucleoside catabolic processGO:00061522050.023
neural tube developmentGO:00219151600.023
positive regulation of leukocyte differentiationGO:1902107860.022
mesoderm developmentGO:00074981000.022
purine containing compound metabolic processGO:00725213110.022
positive regulation of t cell activationGO:00508701010.022
positive regulation of hydrolase activityGO:00513451480.022
Fly
small gtpase mediated signal transductionGO:0007264970.022
regulation of secretionGO:00510462740.022
positive regulation of leukocyte proliferationGO:0070665730.022
central nervous system neuron developmentGO:0021954670.022
central nervous system neuron differentiationGO:00219531620.021
regulation of metal ion transportGO:00109591060.021
associative learningGO:0008306610.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
protein localization to membraneGO:00726571080.021
cellular macromolecule catabolic processGO:00442652060.021
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:200076410.021
bmp signaling pathwayGO:0030509930.021
memoryGO:0007613580.021
amino acid transportGO:0006865610.021
nucleoside triphosphate catabolic processGO:00091432050.021
single organism cell adhesionGO:00986021560.020
Mouse
regulation of ion transmembrane transporter activityGO:0032412540.020
appendage developmentGO:00487361660.020
response to inorganic substanceGO:0010035960.020
regulation of cell activationGO:00508652890.020
kidney developmentGO:00018222130.020
Human Zebrafish Mouse
myeloid cell differentiationGO:00300992330.020
angiogenesisGO:00015252010.020
regulation of neuron differentiationGO:00456642810.019
transmission of nerve impulseGO:0019226760.019
metal ion homeostasisGO:00550651890.019
embryonic limb morphogenesisGO:00303261260.019
proteolysis involved in cellular protein catabolic processGO:00516031470.019
guanosine containing compound metabolic processGO:19010681440.019
organelle fissionGO:00482851700.019
gastrulationGO:00073691160.019
regulation of cell cycle phase transitionGO:1901987770.019
nucleotide catabolic processGO:00091662170.019
purine containing compound catabolic processGO:00725232130.019
positive regulation of cell cycleGO:0045787920.019
positive regulation of nucleotide catabolic processGO:0030813880.019
positive regulation of cell motilityGO:20001471160.019
b cell activationGO:00421131610.019
regulation of syncytium formation by plasma membrane fusionGO:0060142230.019
carbohydrate metabolic processGO:00059752300.019
regulation of neuron apoptotic processGO:00435231220.019
tissue homeostasisGO:00018941150.019
regulation of neural retina developmentGO:006107430.019
hexose transmembrane transportGO:003542870.019
lipid localizationGO:00108761260.018
endocytosisGO:00068971680.018
regulation of cellular component sizeGO:00325351210.018
response to organonitrogen compoundGO:00102432460.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of proteolysisGO:00301621640.018
Fly
digestive tract morphogenesisGO:00485461470.018
regulation of neuron deathGO:19012141340.018
positive regulation of ion transportGO:0043270650.018
positive regulation of protein modification processGO:00314012990.018
protein localization to organelleGO:00333651850.018
microtubule based processGO:00070172360.018
protein processingGO:00164851630.018
regulation of cell motilityGO:20001452360.018
cell maturationGO:00484691270.017
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.017
modification dependent protein catabolic processGO:00199411330.017
cellular response to dna damage stimulusGO:00069742070.017
gliogenesisGO:00420631410.017
negative regulation of molecular functionGO:00440922580.017
renal system processGO:0003014480.017
Zebrafish Fly
macromolecule methylationGO:00434141200.017
cell cycle g1 s phase transitionGO:0044843570.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.017
regulation of nucleotide catabolic processGO:00308111220.017
positive regulation of glial cell proliferationGO:006025240.017
regulation of cell migrationGO:00303342190.017
cell fate specificationGO:0001708720.017
regulation of hormone levelsGO:00108172110.017
negative regulation of cell cycle processGO:0010948690.017
negative regulation of cell developmentGO:00107211690.017
formation of primary germ layerGO:0001704770.017
nucleoside catabolic processGO:00091642060.017
multicellular organismal homeostasisGO:00488711640.017
spermatogenesisGO:00072832840.016
Fly
purine nucleoside metabolic processGO:00422782410.016
ameboidal type cell migrationGO:00016671280.016
microtubule cytoskeleton organizationGO:00002261570.016
positive regulation of gtp catabolic processGO:0033126850.016
regulation of myotube differentiationGO:0010830620.016
stem cell developmentGO:00488642190.016
regulation of protein catabolic processGO:00421761080.016
cellular response to cytokine stimulusGO:00713451890.016
purine ribonucleoside monophosphate metabolic processGO:0009167800.016
divalent inorganic cation homeostasisGO:00725071380.016
proton transportGO:0015992350.016
lateral inhibitionGO:004633110.016
negative regulation of organelle organizationGO:0010639900.016
regulation of leukocyte proliferationGO:00706631210.016
stem cell differentiationGO:00488632680.016
immune response regulating signaling pathwayGO:00027641250.016
positive regulation of proteolysisGO:0045862850.015
Fly
developmental maturationGO:00217001930.015
peptide hormone secretionGO:00300721090.015
calcium ion transportGO:00068161590.015
nucleoside monophosphate metabolic processGO:0009123850.015
epithelium migrationGO:0090132630.015
spermatid differentiationGO:00485151150.015
Fly
positive regulation of gliogenesisGO:0014015270.015
ras protein signal transductionGO:0007265770.015
glial cell apoptotic processGO:003434930.015
mitotic cell cycle processGO:19030471590.015
protein catabolic processGO:00301632210.015
negative regulation of protein modification processGO:00314001630.015
Mouse
intrinsic apoptotic signaling pathwayGO:00971931320.015
monocarboxylic acid transportGO:0015718440.015
cellular protein complex assemblyGO:00436231160.015
peptidyl serine phosphorylationGO:0018105740.015
adult locomotory behaviorGO:0008344910.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
sclerotome developmentGO:006105640.014
regulation of lymphocyte activationGO:00512492400.014
divalent metal ion transportGO:00708381720.014
regulation of leukocyte differentiationGO:19021051590.014
positive regulation of mitotic cell cycleGO:0045931410.014
proteasomal protein catabolic processGO:0010498980.014
b cell proliferationGO:0042100530.014
cellular response to nutrient levelsGO:0031669640.014
response to transforming growth factor betaGO:0071559880.014
fat cell differentiationGO:00454441600.014
asymmetric stem cell divisionGO:009872230.014
regulation of muscle tissue developmentGO:1901861970.014
Fly
regulation of leukocyte apoptotic processGO:2000106560.014
tendon cell differentiationGO:003599040.014
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.014
muscle fiber developmentGO:0048747760.014
Zebrafish
cellular ion homeostasisGO:00068731650.013
regulation of kinase activityGO:00435492490.013
macromolecule catabolic processGO:00090572810.013
modification dependent macromolecule catabolic processGO:00436321330.013
morphogenesis of embryonic epitheliumGO:00163311590.013
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.013
protein targetingGO:00066051430.013
regulation of skeletal muscle fiber developmentGO:0048742360.013
protein acylationGO:0043543640.013
erythrocyte differentiationGO:0030218880.013
response to molecule of bacterial originGO:00022371430.013
cellular response to carbohydrate stimulusGO:0071322500.013
positive regulation of endopeptidase activityGO:0010950430.013
Fly
positive regulation of production of molecular mediator of immune responseGO:0002702450.013
regulation of purine nucleotide catabolic processGO:00331211220.013
regulation of t cell proliferationGO:0042129920.013
mammary gland epithelium developmentGO:0061180650.013
neural nucleus developmentGO:0048857220.013
Mouse
leukocyte apoptotic processGO:0071887710.013
regulation of intracellular transportGO:00323861590.013
axon ensheathmentGO:0008366760.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
response to fructoseGO:000975020.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
regulation of cellular component biogenesisGO:00440871810.013
pallium developmentGO:00215431200.013
homeostasis of number of cellsGO:00488722100.013
positive regulation of organelle organizationGO:00106381280.013
hydrogen transportGO:0006818350.013
regulation of myeloid cell apoptotic processGO:0033032190.013
positive regulation of secretionGO:00510471300.013
renal tubule morphogenesisGO:0061333720.012
nuclear transportGO:00511691390.012
establishment of vesicle localizationGO:0051650810.012
negative regulation of immune system processGO:00026832090.012
cellular amine metabolic processGO:0044106440.012
ribonucleoside monophosphate catabolic processGO:0009158570.012
limb morphogenesisGO:00351081490.012
peptidyl amino acid modificationGO:00181933360.012
neuron apoptotic processGO:00514021420.012
meiotic cell cycleGO:00513211220.012
regulation of lymphocyte proliferationGO:00506701170.012
gtp metabolic processGO:00460391440.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
positive regulation of lymphocyte proliferationGO:0050671700.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.012
cytokine productionGO:00018163190.012
negative regulation of cellular protein metabolic processGO:00322692470.012
Mouse
cellular glucose homeostasisGO:0001678520.012
inorganic anion transportGO:0015698430.012
hydrogen ion transmembrane transportGO:1902600250.012
negative regulation of mitotic cell cycle phase transitionGO:1901991450.012
epithelial cell proliferationGO:00506731740.012
regulation of peptide secretionGO:0002791770.012
embryonic organ morphogenesisGO:00485622760.012
regulation of osteoblast differentiationGO:0045667670.012
sequestering of calcium ionGO:0051208180.012
epithelial tube formationGO:00721751300.012
regulation of adaptive immune responseGO:0002819900.011
regulation of ras gtpase activityGO:0032318880.011
cell adhesionGO:00071553290.011
mitotic nuclear divisionGO:0007067480.011
telencephalon developmentGO:00215371860.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
eosinophil migrationGO:007267730.011
positive regulation of cell activationGO:00508671580.011
regulation of protein targetingGO:1903533610.011
gtp catabolic processGO:00061841430.011
immune response activating signal transductionGO:00027571160.011
embryonic appendage morphogenesisGO:00351131260.011
regulation of t cell activationGO:00508631700.011
multicellular organism growthGO:00352641610.011
cellular metal ion homeostasisGO:00068751510.011
digestive tract developmentGO:00485651900.011
nucleocytoplasmic transportGO:00069131390.011
embryonic epithelial tube formationGO:00018381300.011
hormone secretionGO:00468791280.011
tendon formationGO:003599240.011
regulation of cation channel activityGO:2001257220.011
regulation of cell divisionGO:0051302760.011
mesenchymal cell differentiationGO:00487621070.011
sensory perceptionGO:00076002450.011
regulation of establishment of protein localizationGO:00702011810.011
muscle tissue developmentGO:00605373080.011
cellular response to extracellular stimulusGO:0031668810.011
regulation of blood circulationGO:1903522930.011
digestive system developmentGO:00551232000.011
positive regulation of protein catabolic processGO:0045732600.011
immunoglobulin productionGO:0002377730.011
dna metabolic processGO:00062593030.011
post anal tail morphogenesisGO:0036342230.011
negative regulation of ossificationGO:0030279490.011
purine nucleoside monophosphate catabolic processGO:0009128580.011
t cell proliferationGO:00420981200.011
retina morphogenesis in camera type eyeGO:0060042450.011
actin cytoskeleton organizationGO:00300362200.011
apoptotic signaling pathwayGO:00971903060.010
mitochondrial transportGO:0006839360.010
t cell activationGO:00421102890.010
cellular response to insulin stimulusGO:0032869780.010
oocyte axis specificationGO:000730920.010
alpha amino acid metabolic processGO:1901605590.010
regulation of cell cycle g1 s phase transitionGO:1902806350.010
positive regulation of cell cycle processGO:0090068610.010
protein maturationGO:00516041760.010
b cell apoptotic processGO:0001783190.010
regulation of circadian sleep wake cycleGO:004274930.010
regulation of t cell differentiationGO:0045580830.010
positive regulation of neuron differentiationGO:00456661410.010
negative regulation of neuron apoptotic processGO:0043524920.010
posttranscriptional regulation of gene expressionGO:00106081550.010
embryonic digit morphogenesisGO:0042733560.010
regulation of proteasomal protein catabolic processGO:0061136460.010
protein kinase b signalingGO:0043491740.010
lymphocyte mediated immunityGO:00024491390.010
cation homeostasisGO:00550802120.010
establishment of protein localization to organelleGO:00725941180.010
oxidation reduction processGO:00551143420.010
negative regulation of mitotic cell cycleGO:0045930580.010
g1 s transition of mitotic cell cycleGO:0000082570.010
insulin secretionGO:0030073890.010
activation of immune responseGO:00022531380.010

Nphs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.048
nervous system diseaseDOID:86300.034
disease of anatomical entityDOID:700.034
Human
sensory system diseaseDOID:005015500.019
cancerDOID:16200.018
eye and adnexa diseaseDOID:149200.013
urinary system diseaseDOID:1800.011
Human
bone diseaseDOID:008000100.011
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.011