Mus musculus

70 known processes

Rpa1

replication protein A1

(Aliases: AW557552,AA589576,70kDa,Rpa,RF-A,RP-A,5031405K23Rik)

Rpa1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via nonhomologous end joiningGO:0006303100.480
protein modification by small protein conjugation or removalGO:00706472070.479
Yeast
dna dependent dna replicationGO:0006261240.448
Yeast
deoxyribonucleotide biosynthetic processGO:000926360.422
dna repairGO:00062811070.412
cellular response to dna damage stimulusGO:00069742070.363
dna metabolic processGO:00062593030.326
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.278
chromatin organizationGO:00063252060.253
cell cycle checkpointGO:0000075470.239
intra s dna damage checkpointGO:003157340.213
meiosis iGO:0007127600.180
Yeast
inner cell mass cell proliferationGO:0001833150.178
recombinational repairGO:0000725210.178
mitotic cell cycleGO:00002781950.173
protein modification by small protein conjugationGO:00324461870.148
Yeast
organelle fissionGO:00482851700.141
nucleobase containing small molecule metabolic processGO:00550863520.119
negative regulation of cell cycle processGO:0010948690.106
dna unwinding involved in dna replicationGO:000626850.099
Yeast
dna recombinationGO:0006310920.095
protein dna complex subunit organizationGO:0071824280.095
meiotic cell cycle processGO:1903046770.094
Yeast
positive regulation of cellular amine metabolic processGO:003324050.086
cellular amino acid metabolic processGO:00065201030.084
regulation of mitotic cell cycle phase transitionGO:1901990730.083
dna conformation changeGO:0071103370.083
Yeast
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.082
regulation of sequence specific dna binding transcription factor activityGO:00510901060.080
ras protein signal transductionGO:0007265770.079
positive regulation of cellular amino acid metabolic processGO:004576430.078
cell fate commitmentGO:00451652100.072
base excision repairGO:000628490.071
Human
chromosome organization involved in meiosisGO:0070192390.066
meiotic cell cycleGO:00513211220.065
purine ribonucleoside triphosphate catabolic processGO:00092071990.063
non recombinational repairGO:0000726100.062
dna replication checkpointGO:000007620.061
cellular ketone metabolic processGO:0042180840.060
small gtpase mediated signal transductionGO:0007264970.058
negative regulation of cell cycleGO:00457861230.057
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.055
microtubule cytoskeleton organizationGO:00002261570.055
purine containing compound metabolic processGO:00725213110.055
microtubule based processGO:00070172360.051
mitotic cell cycle processGO:19030471590.051
response to radiationGO:00093141650.049
regulation of intracellular transportGO:00323861590.049
dna templated transcriptional preinitiation complex assemblyGO:007089740.048
protein ubiquitinationGO:00165671710.047
Yeast
regulation of cellular amino acid metabolic processGO:000652150.046
histone acetylationGO:0016573410.046
negative regulation of molecular functionGO:00440922580.046
intracellular protein transportGO:00068862040.046
dna integrity checkpointGO:0031570280.046
nucleoside phosphate biosynthetic processGO:1901293790.044
cell chemotaxisGO:0060326810.043
regulation of hydrolase activityGO:00513362460.043
Worm
organelle assemblyGO:00709251770.043
alpha amino acid metabolic processGO:1901605590.043
amine metabolic processGO:0009308450.042
histone modificationGO:00165701590.040
negative regulation of mitotic cell cycleGO:0045930580.040
methylationGO:00322591340.040
peptidyl amino acid modificationGO:00181933360.039
positive regulation of dna templated transcription initiationGO:200014450.039
double strand break repairGO:0006302480.039
mitotic g1 dna damage checkpointGO:003157140.037
blastocyst growthGO:0001832230.037
regulation of chromosome organizationGO:0033044830.037
purine nucleotide metabolic processGO:00061633020.036
cellular protein complex assemblyGO:00436231160.036
meiotic chromosome segregationGO:0045132190.033
carbohydrate derivative biosynthetic processGO:19011371830.033
regulation of histone modificationGO:0031056560.032
chemotaxisGO:00069352470.032
cellular amine metabolic processGO:0044106440.032
blastocyst developmentGO:0001824800.031
macromolecule methylationGO:00434141200.031
purine ribonucleoside metabolic processGO:00461282410.031
double strand break repair via homologous recombinationGO:0000724210.030
protein modification by small protein removalGO:0070646210.030
respiratory system developmentGO:00605411900.029
aromatic compound catabolic processGO:00194392860.029
protein localization to nucleusGO:00345041210.029
purine nucleotide catabolic processGO:00061952110.029
cellular response to growth factor stimulusGO:00713631970.029
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.027
transcription initiation from rna polymerase ii promoterGO:000636780.027
positive regulation of protein modification processGO:00314012990.026
cellular hyperosmotic salinity responseGO:007147500.026
neuron projection guidanceGO:00974851410.026
regulation of cell cycle processGO:00105641600.026
dna replicationGO:0006260520.026
Human Yeast
organic cyclic compound catabolic processGO:19013612950.026
mitotic sister chromatid segregationGO:0000070140.026
macromolecule catabolic processGO:00090572810.026
gene silencing by rnaGO:0031047190.025
regulation of cellular amine metabolic processGO:0033238200.025
negative regulation of cell cycle phase transitionGO:1901988480.024
deoxyribonucleotide metabolic processGO:0009262140.024
lateral inhibitionGO:004633110.024
organonitrogen compound biosynthetic processGO:19015661920.024
axon guidanceGO:00074111410.024
dna methylationGO:0006306430.024
negative regulation of intracellular signal transductionGO:19025321670.024
synapsisGO:0007129340.023
leukocyte migrationGO:00509001240.023
ribonucleoside metabolic processGO:00091192450.023
camera type eye developmentGO:00430102660.023
dna dependent dna replication maintenance of fidelityGO:004500530.023
regulation of transcription by chromatin organizationGO:003440100.022
negative regulation of organelle assemblyGO:190211620.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
spindle organizationGO:0007051280.022
regulation of cellular ketone metabolic processGO:0010565660.022
protein import into nucleusGO:0006606950.022
telencephalon developmentGO:00215371860.022
organophosphate biosynthetic processGO:00904071220.022
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.022
response to growth factorGO:00708481980.022
lamellipodium organizationGO:0097581290.022
positive regulation of intracellular transportGO:0032388700.021
spermatogenesisGO:00072832840.021
stem cell developmentGO:00488642190.021
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.021
ameboidal type cell migrationGO:00016671280.021
mitotic cell cycle checkpointGO:0007093310.021
oxidation reduction processGO:00551143420.021
nucleotide metabolic processGO:00091173320.021
myeloid leukocyte migrationGO:0097529570.021
regulation of cell cycleGO:00517262810.021
maintenance of protein location in nucleusGO:005145720.020
nucleoside metabolic processGO:00091162460.020
purine nucleoside metabolic processGO:00422782410.020
gtp catabolic processGO:00061841430.020
nucleotide biosynthetic processGO:0009165780.020
engulfment of apoptotic cellGO:004365230.020
positive regulation of protein complex assemblyGO:0031334450.020
regulation of protein acetylationGO:1901983220.020
negative regulation of mitotic cell cycle phase transitionGO:1901991450.020
protein sumoylationGO:0016925140.020
positive regulation of gtpase activityGO:0043547850.019
protein processingGO:00164851630.019
purine nucleoside catabolic processGO:00061522050.019
negative regulation of protein metabolic processGO:00512482820.019
purine ribonucleotide catabolic processGO:00091542080.018
ribonucleoside catabolic processGO:00424542060.018
regulation of response to dna damage stimulusGO:2001020340.018
protein acylationGO:0043543640.018
purine ribonucleoside triphosphate metabolic processGO:00092052200.018
nucleoside phosphate catabolic processGO:19012922220.018
regulation of dna damage checkpointGO:200000130.018
immune effector processGO:00022523210.018
stem cell differentiationGO:00488632680.018
protein targetingGO:00066051430.018
gonad developmentGO:00084061410.018
regulation of organelle organizationGO:00330432890.017
regulation of cell cycle phase transitionGO:1901987770.017
ear developmentGO:00435832000.017
ribonucleotide metabolic processGO:00092592910.017
regulation of mitotic cell cycleGO:00073461260.017
positive regulation of programmed cell deathGO:00430682180.017
positive regulation of intracellular protein transportGO:0090316420.017
regulation of intracellular protein transportGO:0033157820.017
nucleotide excision repairGO:0006289130.017
Human Yeast
dna damage checkpointGO:0000077260.017
mesenchymal cell differentiationGO:00487621070.017
regulation of cellular response to stressGO:00801351590.017
nucleoside triphosphate catabolic processGO:00091432050.017
dna modificationGO:0006304500.017
forebrain developmentGO:00309003020.016
intraspecies interaction between organismsGO:0051703210.016
organophosphate catabolic processGO:00464342320.016
nucleoside phosphate metabolic processGO:00067533380.016
glycosyl compound metabolic processGO:19016572460.016
gene silencingGO:0016458380.016
regulation of rho gtpase activityGO:0032319580.016
mismatch repairGO:000629880.016
Human
antimicrobial peptide productionGO:000277520.016
cofactor metabolic processGO:0051186800.016
ribonucleotide catabolic processGO:00092612080.016
internal peptidyl lysine acetylationGO:0018393420.016
purine nucleoside triphosphate catabolic processGO:00091462030.015
cellular response to transforming growth factor beta stimulusGO:0071560880.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of cellular catabolic processGO:00313292420.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
regulation of cytoplasmic transportGO:19036491120.015
negative regulation of cellular protein metabolic processGO:00322692470.015
glial cell differentiationGO:00100011310.015
response to oxidative stressGO:00069791230.015
posttranscriptional regulation of gene expressionGO:00106081550.015
regulation of protein complex assemblyGO:0043254830.015
cation transportGO:00068123990.015
atp catabolic processGO:0006200550.015
negative regulation of cellular component organizationGO:00511291940.014
axonogenesisGO:00074092740.014
mitotic recombinationGO:000631230.014
Yeast
nitrogen compound transportGO:00717052710.014
ribonucleoside monophosphate metabolic processGO:0009161800.014
positive regulation of ras gtpase activityGO:0032320650.014
nucleus organizationGO:0006997450.014
negative regulation of chromatin silencingGO:003193610.014
response to peptide hormoneGO:00434341270.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
response to light stimulusGO:00094161350.013
response to acid chemicalGO:00011011110.013
regulation of dna bindingGO:0051101390.013
organonitrogen compound catabolic processGO:19015652640.013
dna templated transcription terminationGO:000635340.013
spermatid developmentGO:00072861080.013
ribonucleoside triphosphate catabolic processGO:00092031990.013
leukocyte activation involved in immune responseGO:00023661260.013
cellular nitrogen compound catabolic processGO:00442702800.013
positive regulation of nucleocytoplasmic transportGO:0046824300.013
carbohydrate derivative catabolic processGO:19011362310.013
embryonic organ morphogenesisGO:00485622760.013
pyrimidine containing compound metabolic processGO:0072527110.013
purine containing compound catabolic processGO:00725232130.013
translesion synthesisGO:001998510.013
negative regulation of phosphorylationGO:00423261660.013
lung developmentGO:00303241640.013
regulation of hormone levelsGO:00108172110.013
rna dependent dna replicationGO:000627830.012
Yeast
proteolysis involved in cellular protein catabolic processGO:00516031470.012
regulation of membrane potentialGO:00423911920.012
negative regulation of gene expression epigeneticGO:0045814150.012
regulation of peptidyl lysine acetylationGO:2000756220.012
internal protein amino acid acetylationGO:0006475420.012
divalent metal ion transportGO:00708381720.012
cdc42 protein signal transductionGO:003248800.012
locomotory behaviorGO:00076261950.012
regulation of multi organism processGO:00439001110.012
transcription coupled nucleotide excision repairGO:000628320.012
cation transmembrane transportGO:00986552660.012
positive regulation of gtp catabolic processGO:0033126850.012
regulation of nucleotide catabolic processGO:00308111220.012
rna interferenceGO:001624620.012
protein maturationGO:00516041760.012
heterocycle catabolic processGO:00467002800.012
cell cell signaling involved in cell fate commitmentGO:0045168350.012
rho protein signal transductionGO:0007266320.011
nucleoside triphosphate metabolic processGO:00091412300.011
social behaviorGO:0035176210.011
ribose phosphate metabolic processGO:00196932910.011
peptidyl lysine acetylationGO:0018394450.011
adaptive immune responseGO:00022501550.011
cytoplasmic transportGO:00164822340.011
negative regulation of multi organism processGO:0043901680.011
coenzyme metabolic processGO:0006732520.011
regulation of purine nucleotide metabolic processGO:19005421690.011
liver developmentGO:0001889660.011
regulation of protein transportGO:00512231630.011
mrna transportGO:0051028130.011
response to inorganic substanceGO:0010035960.011
negative regulation of wnt signaling pathwayGO:0030178730.011
nuclear importGO:0051170950.011
purine ribonucleotide metabolic processGO:00091502900.011
male meiosis chromosome segregationGO:000706030.011
b cell activation involved in immune responseGO:0002312500.011
carbohydrate metabolic processGO:00059752300.011
establishment of protein localization to organelleGO:00725941180.011
divalent inorganic cation transportGO:00725111780.011
digestive system developmentGO:00551232000.010
regulation of ras gtpase activityGO:0032318880.010
negative regulation of chromosome organizationGO:2001251300.010
sulfur compound metabolic processGO:00067901000.010
dna templated transcription initiationGO:0006352130.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
regulation of cellular component biogenesisGO:00440871810.010
regulation of purine nucleotide catabolic processGO:00331211220.010

Rpa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hereditary sensory neuropathyDOID:005054800.024
peripheral neuropathyDOID:006005300.024
nervous system diseaseDOID:86300.024
neuropathyDOID:87000.024
disease of anatomical entityDOID:700.024
congenital nervous system abnormalityDOID:249000.022
lissencephalyDOID:005045300.022
physical disorderDOID:008001500.022