| double strand break repair via nonhomologous end joining | GO:0006303 | 10 | 0.480 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.479 | Yeast |
| dna dependent dna replication | GO:0006261 | 24 | 0.448 | Yeast |
| deoxyribonucleotide biosynthetic process | GO:0009263 | 6 | 0.422 | |
| dna repair | GO:0006281 | 107 | 0.412 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.363 | |
| dna metabolic process | GO:0006259 | 303 | 0.326 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.278 | |
| chromatin organization | GO:0006325 | 206 | 0.253 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.239 | |
| intra s dna damage checkpoint | GO:0031573 | 4 | 0.213 | |
| meiosis i | GO:0007127 | 60 | 0.180 | Yeast |
| inner cell mass cell proliferation | GO:0001833 | 15 | 0.178 | |
| recombinational repair | GO:0000725 | 21 | 0.178 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.173 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.148 | Yeast |
| organelle fission | GO:0048285 | 170 | 0.141 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.119 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.106 | |
| dna unwinding involved in dna replication | GO:0006268 | 5 | 0.099 | Yeast |
| dna recombination | GO:0006310 | 92 | 0.095 | |
| protein dna complex subunit organization | GO:0071824 | 28 | 0.095 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.094 | Yeast |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.086 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.084 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.083 | |
| dna conformation change | GO:0071103 | 37 | 0.083 | Yeast |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 2 | 0.082 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.080 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.079 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.078 | |
| cell fate commitment | GO:0045165 | 210 | 0.072 | |
| base excision repair | GO:0006284 | 9 | 0.071 | Human |
| chromosome organization involved in meiosis | GO:0070192 | 39 | 0.066 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.065 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.063 | |
| non recombinational repair | GO:0000726 | 10 | 0.062 | |
| dna replication checkpoint | GO:0000076 | 2 | 0.061 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.060 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.058 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.057 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 5 | 0.055 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.055 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.055 | |
| microtubule based process | GO:0007017 | 236 | 0.051 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.051 | |
| response to radiation | GO:0009314 | 165 | 0.049 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.049 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 4 | 0.048 | |
| protein ubiquitination | GO:0016567 | 171 | 0.047 | Yeast |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.046 | |
| histone acetylation | GO:0016573 | 41 | 0.046 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.046 | |
| intracellular protein transport | GO:0006886 | 204 | 0.046 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.046 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.044 | |
| cell chemotaxis | GO:0060326 | 81 | 0.043 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.043 | Worm |
| organelle assembly | GO:0070925 | 177 | 0.043 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.043 | |
| amine metabolic process | GO:0009308 | 45 | 0.042 | |
| histone modification | GO:0016570 | 159 | 0.040 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.040 | |
| methylation | GO:0032259 | 134 | 0.040 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.039 | |
| positive regulation of dna templated transcription initiation | GO:2000144 | 5 | 0.039 | |
| double strand break repair | GO:0006302 | 48 | 0.039 | |
| mitotic g1 dna damage checkpoint | GO:0031571 | 4 | 0.037 | |
| blastocyst growth | GO:0001832 | 23 | 0.037 | |
| regulation of chromosome organization | GO:0033044 | 83 | 0.037 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.036 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.036 | |
| meiotic chromosome segregation | GO:0045132 | 19 | 0.033 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.033 | |
| regulation of histone modification | GO:0031056 | 56 | 0.032 | |
| chemotaxis | GO:0006935 | 247 | 0.032 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.032 | |
| blastocyst development | GO:0001824 | 80 | 0.031 | |
| macromolecule methylation | GO:0043414 | 120 | 0.031 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.031 | |
| double strand break repair via homologous recombination | GO:0000724 | 21 | 0.030 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.030 | |
| respiratory system development | GO:0060541 | 190 | 0.029 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.029 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.029 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.029 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.029 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 3 | 0.027 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 8 | 0.027 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.026 | |
| cellular hyperosmotic salinity response | GO:0071475 | 0 | 0.026 | |
| neuron projection guidance | GO:0097485 | 141 | 0.026 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.026 | |
| dna replication | GO:0006260 | 52 | 0.026 | Human Yeast |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.026 | |
| mitotic sister chromatid segregation | GO:0000070 | 14 | 0.026 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.026 | |
| gene silencing by rna | GO:0031047 | 19 | 0.025 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.025 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.024 | |
| deoxyribonucleotide metabolic process | GO:0009262 | 14 | 0.024 | |
| lateral inhibition | GO:0046331 | 1 | 0.024 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.024 | |
| axon guidance | GO:0007411 | 141 | 0.024 | |
| dna methylation | GO:0006306 | 43 | 0.024 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.024 | |
| synapsis | GO:0007129 | 34 | 0.023 | |
| leukocyte migration | GO:0050900 | 124 | 0.023 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.023 | |
| camera type eye development | GO:0043010 | 266 | 0.023 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 3 | 0.023 | |
| regulation of transcription by chromatin organization | GO:0034401 | 0 | 0.022 | |
| negative regulation of organelle assembly | GO:1902116 | 2 | 0.022 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.022 | |
| spindle organization | GO:0007051 | 28 | 0.022 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.022 | |
| protein import into nucleus | GO:0006606 | 95 | 0.022 | |
| telencephalon development | GO:0021537 | 186 | 0.022 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.022 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.022 | |
| response to growth factor | GO:0070848 | 198 | 0.022 | |
| lamellipodium organization | GO:0097581 | 29 | 0.022 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.021 | |
| spermatogenesis | GO:0007283 | 284 | 0.021 | |
| stem cell development | GO:0048864 | 219 | 0.021 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.021 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.021 | |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.021 | |
| oxidation reduction process | GO:0055114 | 342 | 0.021 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.021 | |
| myeloid leukocyte migration | GO:0097529 | 57 | 0.021 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.021 | |
| maintenance of protein location in nucleus | GO:0051457 | 2 | 0.020 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.020 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.020 | |
| gtp catabolic process | GO:0006184 | 143 | 0.020 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.020 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.020 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.020 | |
| regulation of protein acetylation | GO:1901983 | 22 | 0.020 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.020 | |
| protein sumoylation | GO:0016925 | 14 | 0.020 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.019 | |
| protein processing | GO:0016485 | 163 | 0.019 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.019 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.019 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.018 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.018 | |
| regulation of response to dna damage stimulus | GO:2001020 | 34 | 0.018 | |
| protein acylation | GO:0043543 | 64 | 0.018 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.018 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.018 | |
| regulation of dna damage checkpoint | GO:2000001 | 3 | 0.018 | |
| immune effector process | GO:0002252 | 321 | 0.018 | |
| stem cell differentiation | GO:0048863 | 268 | 0.018 | |
| protein targeting | GO:0006605 | 143 | 0.018 | |
| gonad development | GO:0008406 | 141 | 0.018 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.017 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.017 | |
| ear development | GO:0043583 | 200 | 0.017 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.017 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.017 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.017 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.017 | |
| nucleotide excision repair | GO:0006289 | 13 | 0.017 | Human Yeast |
| dna damage checkpoint | GO:0000077 | 26 | 0.017 | |
| mesenchymal cell differentiation | GO:0048762 | 107 | 0.017 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.017 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.017 | |
| dna modification | GO:0006304 | 50 | 0.017 | |
| forebrain development | GO:0030900 | 302 | 0.016 | |
| intraspecies interaction between organisms | GO:0051703 | 21 | 0.016 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.016 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.016 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.016 | |
| gene silencing | GO:0016458 | 38 | 0.016 | |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.016 | |
| mismatch repair | GO:0006298 | 8 | 0.016 | Human |
| antimicrobial peptide production | GO:0002775 | 2 | 0.016 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.016 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.016 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.016 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.015 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.015 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.015 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.015 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.015 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.015 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.015 | |
| glial cell differentiation | GO:0010001 | 131 | 0.015 | |
| response to oxidative stress | GO:0006979 | 123 | 0.015 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.015 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.015 | |
| cation transport | GO:0006812 | 399 | 0.015 | |
| atp catabolic process | GO:0006200 | 55 | 0.015 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.014 | |
| axonogenesis | GO:0007409 | 274 | 0.014 | |
| mitotic recombination | GO:0006312 | 3 | 0.014 | Yeast |
| nitrogen compound transport | GO:0071705 | 271 | 0.014 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.014 | |
| positive regulation of ras gtpase activity | GO:0032320 | 65 | 0.014 | |
| nucleus organization | GO:0006997 | 45 | 0.014 | |
| negative regulation of chromatin silencing | GO:0031936 | 1 | 0.014 | |
| response to peptide hormone | GO:0043434 | 127 | 0.013 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.013 | |
| response to light stimulus | GO:0009416 | 135 | 0.013 | |
| response to acid chemical | GO:0001101 | 111 | 0.013 | |
| regulation of dna binding | GO:0051101 | 39 | 0.013 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.013 | |
| dna templated transcription termination | GO:0006353 | 4 | 0.013 | |
| spermatid development | GO:0007286 | 108 | 0.013 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.013 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.013 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.013 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.013 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.013 | |
| pyrimidine containing compound metabolic process | GO:0072527 | 11 | 0.013 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.013 | |
| translesion synthesis | GO:0019985 | 1 | 0.013 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.013 | |
| lung development | GO:0030324 | 164 | 0.013 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.013 | |
| rna dependent dna replication | GO:0006278 | 3 | 0.012 | Yeast |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.012 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.012 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 15 | 0.012 | |
| regulation of peptidyl lysine acetylation | GO:2000756 | 22 | 0.012 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.012 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.012 | |
| cdc42 protein signal transduction | GO:0032488 | 0 | 0.012 | |
| locomotory behavior | GO:0007626 | 195 | 0.012 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.012 | |
| transcription coupled nucleotide excision repair | GO:0006283 | 2 | 0.012 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.012 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.012 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.012 | |
| rna interference | GO:0016246 | 2 | 0.012 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.012 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 35 | 0.012 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.011 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.011 | |
| social behavior | GO:0035176 | 21 | 0.011 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.011 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.011 | |
| adaptive immune response | GO:0002250 | 155 | 0.011 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.011 | |
| negative regulation of multi organism process | GO:0043901 | 68 | 0.011 | |
| coenzyme metabolic process | GO:0006732 | 52 | 0.011 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.011 | |
| liver development | GO:0001889 | 66 | 0.011 | |
| regulation of protein transport | GO:0051223 | 163 | 0.011 | |
| mrna transport | GO:0051028 | 13 | 0.011 | |
| response to inorganic substance | GO:0010035 | 96 | 0.011 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.011 | |
| nuclear import | GO:0051170 | 95 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.011 | |
| male meiosis chromosome segregation | GO:0007060 | 3 | 0.011 | |
| b cell activation involved in immune response | GO:0002312 | 50 | 0.011 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.011 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.011 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.011 | |
| digestive system development | GO:0055123 | 200 | 0.010 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.010 | |
| negative regulation of chromosome organization | GO:2001251 | 30 | 0.010 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.010 | |
| dna templated transcription initiation | GO:0006352 | 13 | 0.010 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.010 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.010 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.010 | |