Mus musculus

39 known processes

Prf1

perforin 1 (pore forming protein)

(Aliases: Pfp,Prf-1,Pfn)

Prf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.997
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.993
natural killer cell activationGO:0030101440.988
defense response to bacteriumGO:00427421190.985
adaptive immune responseGO:00022501550.978
leukocyte mediated immunityGO:00024431740.977
natural killer cell mediated cytotoxicityGO:0042267290.971
cell killingGO:0001906670.970
natural killer cell degranulationGO:004332030.966
lymphocyte mediated immunityGO:00024491390.963
somatic diversification of immune receptorsGO:0002200530.955
cell fate commitmentGO:00451652100.952
peptidyl tyrosine modificationGO:00182121450.950
dna metabolic processGO:00062593030.935
leukocyte proliferationGO:00706611720.929
leukocyte mediated cytotoxicityGO:0001909620.908
cell activation involved in immune responseGO:00022631260.895
regulation of leukocyte mediated immunityGO:00027031040.887
regulation of cellular amine metabolic processGO:0033238200.884
cellular ketone metabolic processGO:0042180840.878
natural killer cell mediated immunityGO:0002228290.877
peptidyl tyrosine phosphorylationGO:00181081430.865
leukocyte activation involved in immune responseGO:00023661260.839
positive regulation of b cell mediated immunityGO:0002714260.831
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.831
lymphocyte proliferationGO:00466511640.819
t cell activationGO:00421102890.815
amine metabolic processGO:0009308450.812
dna recombinationGO:0006310920.808
regulation of lymphocyte mediated immunityGO:0002706840.794
t cell mediated immunityGO:0002456500.794
peptidyl amino acid modificationGO:00181933360.792
somatic cell dna recombinationGO:0016444510.791
negative regulation of lymphocyte activationGO:0051250910.791
epithelial cell proliferationGO:00506731740.790
natural killer cell activation involved in immune responseGO:0002323100.785
reactive oxygen species metabolic processGO:0072593840.782
defense response to other organismGO:00985421970.781
regulation of inflammatory response to antigenic stimulusGO:0002861210.775
negative regulation of immune effector processGO:0002698550.774
cellular response to cytokine stimulusGO:00713451890.772
positive regulation of isotype switching to igg isotypesGO:004830470.770
b cell activationGO:00421131610.765
regulation of peptidyl tyrosine phosphorylationGO:0050730930.762
somatic diversification of immunoglobulinsGO:0016445430.750
positive regulation of lymphocyte mediated immunityGO:0002708620.746
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.742
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.722
regulation of dna recombinationGO:0000018340.722
regulation of lymphocyte activationGO:00512492400.718
cytokine mediated signaling pathwayGO:00192211150.718
somatic recombination of immunoglobulin gene segmentsGO:0016447420.717
immune effector processGO:00022523210.713
positive regulation of activated t cell proliferationGO:004210480.709
jak stat cascadeGO:0007259420.700
leukocyte homeostasisGO:0001776790.680
regulation of isotype switchingGO:0045191220.678
regulation of t cell activationGO:00508631700.672
regulation of b cell activationGO:0050864810.672
negative regulation of inflammatory responseGO:0050728610.671
cellular amine metabolic processGO:0044106440.671
immunoglobulin mediated immune responseGO:0016064690.667
t cell proliferationGO:00420981200.631
positive regulation of lymphocyte proliferationGO:0050671700.630
response to peptideGO:19016521360.630
cell type specific apoptotic processGO:00972852680.628
lymphocyte activation involved in immune responseGO:0002285930.612
leukocyte apoptotic processGO:0071887710.611
t cell differentiationGO:00302171740.605
regulation of leukocyte proliferationGO:00706631210.592
positive regulation of leukocyte mediated immunityGO:0002705700.591
t cell activation involved in immune responseGO:0002286430.588
regulation of cell activationGO:00508652890.585
stem cell maintenanceGO:00198271300.580
innate immune responseGO:00450871570.569
regulation of peptidase activityGO:0052547960.562
negative regulation of interleukin 5 productionGO:003271440.560
regulation of b cell mediated immunityGO:0002712370.559
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.555
regulation of endopeptidase activityGO:0052548890.546
cytokine biosynthetic processGO:0042089680.543
cellular response to lipidGO:00713961450.541
regulation of lymphocyte differentiationGO:00456191070.539
regulation of interleukin 6 productionGO:0032675550.537
leukocyte degranulationGO:0043299270.534
regulation of b cell differentiationGO:0045577230.529
regulation of epithelial cell proliferationGO:00506781410.526
regulation of cellular amino acid metabolic processGO:000652150.521
positive regulation of cellular amino acid metabolic processGO:004576430.516
myeloid cell activation involved in immune responseGO:0002275340.516
regulation of lymphocyte proliferationGO:00506701170.516
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.516
t cell selectionGO:0045058340.508
production of molecular mediator of immune responseGO:00024401030.505
negative regulation of cell activationGO:00508661110.503
regulation of leukocyte differentiationGO:19021051590.499
homeostasis of number of cellsGO:00488722100.492
regulation of cell cycleGO:00517262810.492
isotype switching to igg isotypesGO:0048291100.489
melanocyte differentiationGO:0030318250.489
regulation of interleukin 2 productionGO:0032663280.487
positive regulation of protein phosphorylationGO:00019342420.471
myeloid leukocyte mediated immunityGO:0002444420.470
digestive tract developmentGO:00485651900.469
alpha beta t cell lineage commitmentGO:000236370.468
establishment of melanosome localizationGO:0032401110.460
regulation of tolerance induction dependent upon immune responseGO:000265210.450
b cell proliferationGO:0042100530.446
regulation of adaptive immune responseGO:0002819900.441
lymphocyte homeostasisGO:0002260640.441
cellular response to biotic stimulusGO:0071216920.441
regulation of angiogenesisGO:0045765810.438
Mouse
regulation of cysteine type endopeptidase activityGO:2000116650.436
regulation of jak stat cascadeGO:0046425340.435
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.435
myeloid cell homeostasisGO:00022621140.430
isotype switchingGO:0045190360.426
erk1 and erk2 cascadeGO:0070371770.425
positive regulation of reactive oxygen species biosynthetic processGO:190342820.421
positive regulation of interferon gamma productionGO:0032729390.421
regulation of cellular ketone metabolic processGO:0010565660.420
positive regulation of production of molecular mediator of immune responseGO:0002702450.418
lymphocyte differentiationGO:00300982420.415
regulation of sequence specific dna binding transcription factor activityGO:00510901060.412
positive regulation of t cell proliferationGO:0042102520.408
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.406
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.401
negative regulation of adaptive immune responseGO:0002820250.400
cd4 positive alpha beta t cell differentiationGO:0043367410.397
regulation of immunoglobulin mediated immune responseGO:0002889370.395
myeloid cell differentiationGO:00300992330.392
natural killer cell proliferationGO:000178730.390
isotype switching to ige isotypesGO:004828970.388
negative regulation of defense responseGO:0031348770.383
myeloid leukocyte differentiationGO:00025731190.380
immune response activating signal transductionGO:00027571160.374
cellular amino acid metabolic processGO:00065201030.365
regulation of body fluid levelsGO:00508781620.362
positive regulation of map kinase activityGO:0043406840.360
regulated secretory pathwayGO:0045055320.355
positive regulation of protein modification processGO:00314012990.352
inflammatory responseGO:00069542440.345
Mouse
negative regulation of b cell activationGO:0050869270.344
regulation of cytokine biosynthetic processGO:0042035590.340
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.340
urogenital system developmentGO:00016552610.339
cytokine productionGO:00018163190.339
myeloid leukocyte activationGO:0002274830.335
regulation of cytokine productionGO:00018172660.331
digestive system developmentGO:00551232000.329
positive regulation of gamma delta t cell differentiationGO:004558860.325
gonad developmentGO:00084061410.322
cellular response to dna damage stimulusGO:00069742070.318
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.314
mast cell proliferationGO:007066240.311
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.309
positive regulation of b cell activationGO:0050871490.306
sphingolipid metabolic processGO:0006665450.306
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.304
regulation of reactive oxygen species metabolic processGO:2000377400.297
negative regulation of t cell activationGO:0050868650.293
cell chemotaxisGO:0060326810.292
extrinsic apoptotic signaling pathwayGO:00971911260.292
t cell differentiation in thymusGO:0033077770.290
positive regulation of mitotic cell cycleGO:0045931410.281
protein maturationGO:00516041760.278
Mouse
cellular lipid metabolic processGO:00442553230.277
positive regulation of cytokine productionGO:00018191740.275
cellular response to lipopolysaccharideGO:0071222770.271
v d j recombinationGO:0033151140.267
tyrosine phosphorylation of stat proteinGO:0007260230.261
regulation of map kinase activityGO:00434051200.255
positive regulation of isotype switchingGO:0045830150.252
positive regulation of mapk cascadeGO:00434101700.249
growth of symbiont in hostGO:0044117230.248
positive regulation of cell cycleGO:0045787920.248
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.247
t helper 1 cell lineage commitmentGO:000229620.241
regulation of innate immune responseGO:0045088910.237
positive regulation of dna recombinationGO:0045911170.236
negative regulation of chronic inflammatory responseGO:000267730.236
regulation of myeloid leukocyte differentiationGO:0002761580.235
response to radiationGO:00093141650.231
synaptic transmissionGO:00072683290.230
t cell lineage commitmentGO:0002360130.228
regulation of interferon gamma productionGO:0032649570.226
b cell activation involved in immune responseGO:0002312500.222
antibacterial humoral responseGO:001973180.218
immunoglobulin productionGO:0002377730.218
antibacterial peptide productionGO:000277820.217
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.215
response to growth factorGO:00708481980.211
response to acid chemicalGO:00011011110.207
pattern recognition receptor signaling pathwayGO:0002221470.205
regulation of kinase activityGO:00435492490.203
immature b cell differentiationGO:0002327100.202
negative regulation of immune system processGO:00026832090.200
interleukin 6 productionGO:0032635580.198
stem cell developmentGO:00488642190.198
cytokine production involved in immune responseGO:0002367340.198
humoral immune responseGO:0006959570.198
Mouse
chronic inflammatory responseGO:000254490.197
myeloid cell apoptotic processGO:0033028220.194
melanosome transportGO:0032402110.194
erythrocyte differentiationGO:0030218880.191
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.190
angiogenesisGO:00015252010.189
Mouse
digestive tract morphogenesisGO:00485461470.189
regulation of t cell differentiationGO:0045580830.189
positive regulation of adaptive immune responseGO:0002821610.185
positive regulation of cysteine type endopeptidase activityGO:2001056390.184
response to lipopolysaccharideGO:00324961280.182
positive regulation of lymphocyte activationGO:00512511400.180
positive t cell selectionGO:0043368230.179
cardiac muscle cell differentiationGO:0055007690.179
signal transduction in absence of ligandGO:0038034550.178
regulation of isotype switching to ige isotypesGO:004829370.177
positive regulation of secretionGO:00510471300.170
positive regulation of innate immune responseGO:0045089800.168
neutrophil mediated immunityGO:0002446190.166
positive regulation of leukocyte proliferationGO:0070665730.164
positive regulation of isotype switching to ige isotypesGO:004829540.163
t cell differentiation involved in immune responseGO:0002292300.162
positive regulation of cell activationGO:00508671580.161
defense response to gram positive bacteriumGO:0050830500.159
inflammatory response to antigenic stimulusGO:0002437300.158
regulation of secretion by cellGO:19035302490.158
t helper cell differentiationGO:0042093280.156
t helper cell lineage commitmentGO:000229560.155
mammary gland epithelial cell proliferationGO:0033598240.154
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.153
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.153
mitotic nuclear divisionGO:0007067480.152
protein processingGO:00164851630.151
Mouse
response to amino acidGO:0043200370.151
positive regulation of immune effector processGO:00026991070.151
Mouse
cd4 positive alpha beta t cell lineage commitmentGO:004337360.149
exocrine system developmentGO:0035272450.146
lung developmentGO:00303241640.145
muscle cell proliferationGO:0033002520.145
positive regulation of protein serine threonine kinase activityGO:00719021060.145
symbiosis encompassing mutualism through parasitismGO:0044403830.144
tumor necrosis factor mediated signaling pathwayGO:0033209130.144
positive regulation of protein kinase activityGO:00458601440.143
thymic t cell selectionGO:0045061220.142
ameboidal type cell migrationGO:00016671280.141
positive regulation of antibacterial peptide biosynthetic processGO:000696310.140
fertilizationGO:00095661270.139
gland developmentGO:00487323300.138
regulation of protein kinase activityGO:00458592320.137
endocrine system developmentGO:0035270980.136
t cell homeostasisGO:0043029350.135
regulation of toll like receptor 4 signaling pathwayGO:003414340.135
cellular response to molecule of bacterial originGO:0071219830.134
positive regulation of kinase activityGO:00336741550.134
cytotoxic t cell degranulationGO:004331620.134
regulation of mast cell proliferationGO:007066640.133
response to endoplasmic reticulum stressGO:0034976530.131
extracellular matrix organizationGO:00301981470.131
b cell mediated immunityGO:0019724710.130
cellular component assembly involved in morphogenesisGO:00109271390.130
granulocyte activationGO:0036230100.130
regulation of immunoglobulin productionGO:0002637420.130
establishment of pigment granule localizationGO:0051905120.129
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.129
regulation of prostaglandin endoperoxide synthase activityGO:006058420.128
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.128
activation of mapk activityGO:0000187590.128
regulation of interleukin 5 secretionGO:200066220.127
positive regulation of proteolysisGO:0045862850.127
microtubule based processGO:00070172360.127
epidermis developmentGO:00085441870.126
negative regulation of vasculature developmentGO:1901343260.126
activation of cysteine type endopeptidase activityGO:0097202270.125
positive regulation of protein kinase b signalingGO:0051897320.125
chromatin organizationGO:00063252060.125
leukocyte differentiationGO:00025213420.124
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.124
nuclear divisionGO:00002801580.124
positive regulation of immunoglobulin mediated immune responseGO:0002891260.123
response to molecule of bacterial originGO:00022371430.123
columnar cuboidal epithelial cell differentiationGO:0002065820.123
intracellular protein transportGO:00068862040.122
organelle fissionGO:00482851700.121
cellular response to amino acid stimulusGO:0071230290.121
positive regulation of response to woundingGO:1903036660.120
regulation of proteolysisGO:00301621640.120
protein targetingGO:00066051430.120
morphogenesis of a branching epitheliumGO:00611381930.119
hindbrain developmentGO:00309021280.119
leukocyte chemotaxisGO:0030595690.118
positive regulation of cellular amine metabolic processGO:003324050.118
regulation of mitosisGO:0007088290.118
progesterone metabolic processGO:004244840.117
positive regulation of immunoglobulin productionGO:0002639280.117
positive regulation of reactive oxygen species metabolic processGO:2000379110.115
positive regulation of angiogenesisGO:0045766460.114
Mouse
positive regulation of jak stat cascadeGO:0046427220.114
defense response to protozoanGO:0042832250.113
regulation of mapk cascadeGO:00434082480.113
regulation of erk1 and erk2 cascadeGO:0070372710.113
b cell differentiationGO:0030183780.111
t cell mediated cytotoxicityGO:0001913260.111
response to hydrogen peroxideGO:0042542320.110
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.109
organelle assemblyGO:00709251770.109
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.109
positive regulation of defense responseGO:00313491240.109
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.108
muscle cell developmentGO:00550011330.107
detection of stimulusGO:0051606840.107
positive regulation of intracellular transportGO:0032388700.106
positive regulation of epithelial cell proliferationGO:0050679680.105
negative regulation of leukocyte differentiationGO:1902106510.105
regulation of mesenchymal cell proliferationGO:0010464370.104
positive regulation of notch signaling pathwayGO:0045747180.103
negative regulation of b cell mediated immunityGO:000271370.103
detection of external stimulusGO:0009581610.102
anatomical structure homeostasisGO:00602491450.102
striated muscle cell developmentGO:00550021250.101
regulation of inflammatory responseGO:00507271470.100
Mouse
regulation of regulated secretory pathwayGO:1903305200.099
exocytosisGO:00068871210.099
immune response activating cell surface receptor signaling pathwayGO:0002429720.099
regulation of mitotic cell cycleGO:00073461260.098
positive regulation of chemotaxisGO:0050921380.097
macromolecule catabolic processGO:00090572810.096
response to insulinGO:00328681000.096
respiratory system developmentGO:00605411900.096
stem cell differentiationGO:00488632680.096
inflammatory cell apoptotic processGO:0006925110.095
t helper 2 cell differentiationGO:0045064120.095
regulation of alpha beta t cell differentiationGO:0046637350.095
alpha beta t cell activationGO:0046631910.095
regulation of transferase activityGO:00513382630.093
positive regulation of peptidase activityGO:0010952490.093
positive regulation of cell cycle processGO:0090068610.093
cellular response to growth factor stimulusGO:00713631970.093
regulation of myeloid cell differentiationGO:0045637960.093
response to organic cyclic compoundGO:00140701980.092
positive regulation of natural killer cell mediated immunityGO:0002717160.091
antigen receptor mediated signaling pathwayGO:0050851640.091
cellular response to fibroblast growth factor stimulusGO:0044344470.091
negative regulation of molecular functionGO:00440922580.090
response to oxygen levelsGO:0070482620.090
negative regulation of response to woundingGO:1903035770.090
pigment granule localizationGO:0051875130.089
positive regulation of myeloid cell differentiationGO:0045639430.089
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.088
regulation of nuclear divisionGO:0051783560.086
odontogenesisGO:0042476780.086
membrane lipid metabolic processGO:0006643530.086
cellular macromolecule catabolic processGO:00442652060.086
activation of mapk activity involved in innate immune responseGO:003541920.085
negative regulation of multi organism processGO:0043901680.085
mitotic cell cycleGO:00002781950.085
positive regulation of mitosisGO:0045840140.084
negative regulation of apoptotic signaling pathwayGO:20012341040.083
osteoclast differentiationGO:0030316620.083
mucosal associated lymphoid tissue developmentGO:0048537120.082
regulation of ion transportGO:00432692150.082
positive regulation of endopeptidase activityGO:0010950430.082
alpha beta t cell proliferationGO:0046633210.081
regulation of interleukin 13 secretionGO:200066520.080
lymph node developmentGO:0048535180.080
neutrophil apoptotic processGO:000178130.080
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.080
rhythmic processGO:00485111740.080
Rat
muscle tissue developmentGO:00605373080.080
response to interleukin 15GO:007067230.079
cellular response to peptideGO:1901653920.079
regulation of toll like receptor 2 signaling pathwayGO:003413530.079
regulation of antigen receptor mediated signaling pathwayGO:0050854290.079
prolactin signaling pathwayGO:003816150.078
phosphatidylinositol 3 kinase signalingGO:0014065360.078
positive regulation of t cell differentiationGO:0045582520.078
positive regulation of programmed cell deathGO:00430682180.078
regionalizationGO:00030023370.076
neutrophil activationGO:004211990.076
mammary gland lobule developmentGO:0061377220.075
negative regulation of cellular amine metabolic processGO:003323910.075
regulation of tumor necrosis factor productionGO:0032680490.074
nuclear transportGO:00511691390.074
positive regulation of mesenchymal cell proliferationGO:0002053330.074
chemotaxisGO:00069352470.074
establishment of protein localization to organelleGO:00725941180.073
positive regulation of stress activated mapk cascadeGO:0032874480.072
skin developmentGO:00435882200.072
regulation of production of molecular mediator of immune responseGO:0002700650.071
negative regulation of hypersensitivityGO:000288430.071
positive regulation of translational initiationGO:004594840.071
positive regulation of t cell activationGO:00508701010.070
interleukin 10 secretionGO:007260840.070
negative regulation of epithelial cell proliferationGO:0050680640.069
regulation of jun kinase activityGO:0043506400.069
t cell receptor signaling pathwayGO:0050852460.069
regulation of protein complex assemblyGO:0043254830.069
positive regulation of behaviorGO:0048520400.069
endodermal cell fate specificationGO:000171440.069
negative regulation of myeloid cell apoptotic processGO:0033033110.068
regulation of cell cycle processGO:00105641600.068
response to protozoanGO:0001562280.068
positive regulation of apoptotic processGO:00430652170.067
smooth muscle tissue developmentGO:0048745220.066
nucleic acid phosphodiester bond hydrolysisGO:0090305490.066
positive regulation of b cell differentiationGO:0045579130.066
negative regulation of cell proliferationGO:00082852960.065
pigment granule transportGO:0051904120.065
regulation of alpha beta t cell activationGO:0046634530.065
regulation of chemotaxisGO:0050920530.064
regulation of hydrolase activityGO:00513362460.064
pigment cell differentiationGO:0050931270.064
organ or tissue specific immune responseGO:0002251130.064
positive regulation of cytokine biosynthetic processGO:0042108400.063
eosinophil activationGO:004330710.062
cellular response to steroid hormone stimulusGO:0071383330.062
apoptotic signaling pathwayGO:00971903060.062
lung cell differentiationGO:0060479300.062
glycolipid metabolic processGO:0006664250.062
inositol lipid mediated signalingGO:0048017410.061
detection of abiotic stimulusGO:0009582600.061
negative regulation of growth of symbiont in hostGO:0044130190.060
regulation of secretionGO:00510462740.060
modulation of growth of symbiont involved in interaction with hostGO:0044144190.060
liposaccharide metabolic processGO:1903509270.060
respiratory tube developmentGO:00303231670.060
regulation of neuron projection developmentGO:00109751690.059
alpha beta t cell differentiationGO:0046632690.059
positive regulation of leukocyte differentiationGO:1902107860.059
regulation of acute inflammatory responseGO:0002673270.059
Mouse
positive regulation of transferase activityGO:00513471670.058
sulfur compound metabolic processGO:00067901000.058
regulation of lipid metabolic processGO:00192161180.058
cell divisionGO:00513011200.058
immune response regulating cell surface receptor signaling pathwayGO:0002768800.058
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.058
sensory organ morphogenesisGO:00905962420.058
striated muscle tissue developmentGO:00147062930.058
positive regulation of interleukin 12 productionGO:0032735210.058
positive regulation of mhc class ii biosynthetic processGO:004534840.057
regulation of defense responseGO:00313472330.057
Mouse
embryonic organ morphogenesisGO:00485622760.057
single fertilizationGO:0007338820.057
regulation of myeloid cell apoptotic processGO:0033032190.057
cytokine metabolic processGO:0042107710.056
single organism cell adhesionGO:00986021560.056
negative regulation of hydrolase activityGO:0051346710.056
negative regulation of protein maturationGO:1903318790.056
phosphatidylinositol mediated signalingGO:0048015410.055
muscle cell differentiationGO:00426922610.055
regulation of vasculature developmentGO:1901342880.055
Mouse
learning or memoryGO:00076111480.054
negative regulation of myeloid dendritic cell activationGO:003088630.054
transmembrane transportGO:00550854120.054
interleukin 1 productionGO:0032612310.053
positive regulation of interleukin 2 biosynthetic processGO:004508680.053
protein kinase b signalingGO:0043491740.053
nucleocytoplasmic transportGO:00069131390.053
nucleotide metabolic processGO:00091173320.053
organic hydroxy compound metabolic processGO:19016152030.053
development of primary female sexual characteristicsGO:0046545730.053
negative regulation of interleukin 2 biosynthetic processGO:004508530.053
negative regulation of toll like receptor signaling pathwayGO:0034122140.053
histone lysine methylationGO:0034968500.052
negative regulation of interleukin 6 productionGO:0032715170.052
regulation of chronic inflammatory responseGO:000267670.052
positive regulation of regulatory t cell differentiationGO:004559140.052
regulation of vesicle mediated transportGO:00606271390.052
immune response regulating signaling pathwayGO:00027641250.051
skeletal muscle organ developmentGO:00605381630.051
negative regulation of type 2 immune responseGO:000282980.050
regulation of growth of symbiont in hostGO:0044126190.050
interleukin 2 biosynthetic processGO:0042094150.050
face developmentGO:0060324380.050
positive regulation of cell deathGO:00109422240.050
regulation of b cell proliferationGO:0030888390.049
positive regulation of alpha beta t cell activationGO:0046635390.049
lung alveolus developmentGO:0048286450.049
protein acylationGO:0043543640.049
regulation of cell divisionGO:0051302760.049
mast cell activationGO:0045576270.049
negative regulation of interleukin 2 productionGO:003270380.049
negative regulation of leukocyte proliferationGO:0070664460.048

Prf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.667
Human
disease of cellular proliferationDOID:1456600.667
Human
organ system cancerDOID:005068600.667
Human
immune system diseaseDOID:291400.274
Human
disease of anatomical entityDOID:700.274
Human
disease of metabolismDOID:001466700.131
carbohydrate metabolism diseaseDOID:005001300.131
glucose metabolism diseaseDOID:419400.131
acquired metabolic diseaseDOID:006015800.131
immune system cancerDOID:006008300.123
Human
hematologic cancerDOID:253100.123
Human
diabetes mellitusDOID:935100.071