Mus musculus

115 known processes

Nlgn2

neuroligin 2

(Aliases: RP23-422L16.24,MGC67386,NL2)

Nlgn2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342203610.148
regulation of membrane potentialGO:00423911920.088
actin cytoskeleton organizationGO:00300362200.069
positive regulation of nervous system developmentGO:00519622210.069
Mouse Rat
positive regulation of cellular amino acid metabolic processGO:004576430.066
cation transportGO:00068123990.066
synaptic transmissionGO:00072683290.066
axonogenesisGO:00074092740.065
positive regulation of cell developmentGO:00107202370.064
regulation of secretion by cellGO:19035302490.064
Mouse
response to light stimulusGO:00094161350.063
Mouse
transmembrane transportGO:00550854120.061
regulation of cellular component biogenesisGO:00440871810.060
Mouse Rat
nucleotide metabolic processGO:00091173320.059
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.057
neuron projection guidanceGO:00974851410.056
inorganic ion transmembrane transportGO:00986602340.055
regulation of cellular amino acid metabolic processGO:000652150.049
ras protein signal transductionGO:0007265770.048
small gtpase mediated signal transductionGO:0007264970.048
cellular amino acid metabolic processGO:00065201030.048
glutamate receptor signaling pathwayGO:0007215350.048
inorganic cation transmembrane transportGO:00986622070.047
regulation of vesicle mediated transportGO:00606271390.047
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.046
Mouse
organic anion transportGO:00157111370.045
regulation of cell motilityGO:20001452360.044
membrane depolarizationGO:0051899640.044
regulation of neuron differentiationGO:00456642810.044
Mouse
regulation of organelle organizationGO:00330432890.044
organelle localizationGO:00516401790.043
Mouse
cation transmembrane transportGO:00986552660.043
regulation of synaptic growth at neuromuscular junctionGO:000858240.043
positive regulation of protein modification processGO:00314012990.043
positive regulation of cellular amine metabolic processGO:003324050.042
ribose phosphate metabolic processGO:00196932910.042
purine ribonucleotide metabolic processGO:00091502900.042
nucleoside metabolic processGO:00091162460.042
cell adhesionGO:00071553290.042
Mouse Rat
regulation of anatomical structure sizeGO:00900661780.041
organonitrogen compound catabolic processGO:19015652640.041
endocytosisGO:00068971680.041
Mouse
amine metabolic processGO:0009308450.040
rho protein signal transductionGO:0007266320.040
protein catabolic processGO:00301632210.040
anion transportGO:00068201770.039
response to radiationGO:00093141650.039
Mouse
developmental growth involved in morphogenesisGO:00605601380.039
membrane organizationGO:00610242450.039
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.038
chemotaxisGO:00069352470.038
cellular ketone metabolic processGO:0042180840.038
regulation of neuron projection developmentGO:00109751690.038
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.037
purine containing compound metabolic processGO:00725213110.037
positive regulation of cell projection organizationGO:0031346950.037
regulation of cell activationGO:00508652890.037
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.037
Mouse
lateral inhibitionGO:004633110.036
aromatic compound catabolic processGO:00194392860.036
cellular chemical homeostasisGO:00550822150.036
cellular homeostasisGO:00197252400.036
negative regulation of phosphorus metabolic processGO:00105631840.036
dendrite developmentGO:00163581150.036
Mouse
ribonucleoside catabolic processGO:00424542060.036
regulation of transferase activityGO:00513382630.035
nucleobase containing small molecule metabolic processGO:00550863520.035
t cell activationGO:00421102890.035
regulation of hydrolase activityGO:00513362460.035
purine containing compound catabolic processGO:00725232130.035
negative regulation of protein metabolic processGO:00512482820.035
regulation of cellular amine metabolic processGO:0033238200.035
cellular response to lipidGO:00713961450.035
regulation of cellular ketone metabolic processGO:0010565660.034
negative regulation of cell proliferationGO:00082852960.034
cellular amine metabolic processGO:0044106440.034
purine nucleotide metabolic processGO:00061633020.034
leukocyte differentiationGO:00025213420.034
regulation of cytokine productionGO:00018172660.034
lymphocyte differentiationGO:00300982420.034
negative regulation of molecular functionGO:00440922580.033
purine ribonucleoside triphosphate catabolic processGO:00092071990.033
positive regulation of neuron differentiationGO:00456661410.033
sensory perceptionGO:00076002450.032
regulation of ion transportGO:00432692150.032
nucleoside phosphate metabolic processGO:00067533380.032
negative regulation of phosphate metabolic processGO:00459361840.032
rhythmic processGO:00485111740.032
response to organonitrogen compoundGO:00102432460.032
cytokine productionGO:00018163190.032
muscle tissue developmentGO:00605373080.032
cell growthGO:00160491300.032
purine ribonucleoside metabolic processGO:00461282410.032
protein modification by small protein conjugationGO:00324461870.031
forebrain developmentGO:00309003020.031
compound eye developmentGO:004874910.031
negative regulation of immune system processGO:00026832090.031
ribonucleotide catabolic processGO:00092612080.031
regulation of t cell activationGO:00508631700.030
regulation of protein kinase activityGO:00458592320.030
organic cyclic compound catabolic processGO:19013612950.030
positive regulation of protein phosphorylationGO:00019342420.030
regulation of cell projection organizationGO:00313442060.030
Mouse
macromolecule catabolic processGO:00090572810.030
locomotory behaviorGO:00076261950.030
glycosyl compound catabolic processGO:19016582060.029
carbohydrate metabolic processGO:00059752300.029
protein modification by small protein conjugation or removalGO:00706472070.029
cation homeostasisGO:00550802120.029
regulation of cytoskeleton organizationGO:00514931220.029
regulation of secretionGO:00510462740.027
Mouse
regulation of glutamate receptor signaling pathwayGO:1900449160.027
response to organic cyclic compoundGO:00140701980.027
guanosine containing compound metabolic processGO:19010681440.027
muscle system processGO:00030121410.027
developmental cell growthGO:0048588840.027
cognitionGO:00508901490.027
Mouse
t cell differentiationGO:00302171740.027
negative regulation of cellular protein metabolic processGO:00322692470.027
nucleotide catabolic processGO:00091662170.027
neuroblast division in subventricular zoneGO:002184920.027
nucleoside triphosphate metabolic processGO:00091412300.027
neuromuscular process controlling balanceGO:0050885590.027
respiratory system developmentGO:00605411900.026
maternal determination of anterior posterior axis embryoGO:000835820.026
protein localization to membraneGO:00726571080.026
mapk cascadeGO:00001652810.026
glycosyl compound metabolic processGO:19016572460.025
immune effector processGO:00022523210.025
purine nucleoside catabolic processGO:00061522050.025
positive regulation of neuron projection developmentGO:0010976790.025
purine nucleoside metabolic processGO:00422782410.024
gonad developmentGO:00084061410.024
cellular divalent inorganic cation homeostasisGO:00725031270.024
regulation of postsynaptic membrane potentialGO:0060078480.024
axon guidanceGO:00074111410.024
wnt signaling pathwayGO:00160551880.024
microtubule based processGO:00070172360.024
circadian rhythmGO:00076231140.024
heterocycle catabolic processGO:00467002800.024
posttranscriptional regulation of gene expressionGO:00106081550.024
carbohydrate derivative catabolic processGO:19011362310.023
dorsal ventral axon guidanceGO:003356330.023
ribonucleotide metabolic processGO:00092592910.023
regulation of circadian rhythmGO:0042752580.023
mitotic cell cycleGO:00002781950.023
regulation of mapk cascadeGO:00434082480.023
multicellular organismal homeostasisGO:00488711640.023
nitrogen compound transportGO:00717052710.022
regulation of endocytosisGO:0030100690.022
Mouse
cellular nitrogen compound catabolic processGO:00442702800.022
myeloid cell differentiationGO:00300992330.022
divalent metal ion transportGO:00708381720.022
muscle cell differentiationGO:00426922610.022
metal ion homeostasisGO:00550651890.022
striated muscle tissue developmentGO:00147062930.022
ribonucleoside metabolic processGO:00091192450.022
development of primary sexual characteristicsGO:00451371430.022
negative regulation of intracellular signal transductionGO:19025321670.022
ionotropic glutamate receptor signaling pathwayGO:0035235290.022
ribonucleoside triphosphate metabolic processGO:00091992200.022
regulation of cell cycleGO:00517262810.021
adult behaviorGO:00305341350.021
Rat Fly
detection of stimulusGO:0051606840.021
cellular ion homeostasisGO:00068731650.021
nucleoside phosphate catabolic processGO:19012922220.021
regulation of receptor activityGO:0010469410.021
epithelial tube morphogenesisGO:00605623030.021
nucleoside catabolic processGO:00091642060.021
organophosphate catabolic processGO:00464342320.021
peptidyl amino acid modificationGO:00181933360.021
synapse assemblyGO:0007416560.021
cellular response to hormone stimulusGO:00328701500.021
regulation of synaptic vesicle exocytosisGO:2000300110.021
Mouse
calcium ion transmembrane transportGO:0070588850.021
purine nucleotide catabolic processGO:00061952110.020
regulation of lymphocyte activationGO:00512492400.020
pole plasm assemblyGO:000731520.020
actin filament polymerizationGO:0030041440.020
spermatogenesisGO:00072832840.020
negative regulation of t cell activationGO:0050868650.020
positive regulation of cell deathGO:00109422240.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
homeostasis of number of cellsGO:00488722100.020
cellular calcium ion homeostasisGO:00068741190.020
regulation of cellular catabolic processGO:00313292420.019
regulation of kinase activityGO:00435492490.019
regulation of ion transmembrane transportGO:00347651190.019
regulation of ras protein signal transductionGO:00465781140.019
cell fate commitmentGO:00451652100.019
multicellular organismal signalingGO:0035637910.019
blood circulationGO:00080151950.019
nucleoside triphosphate catabolic processGO:00091432050.019
negative regulation of protein phosphorylationGO:00019331260.019
ossificationGO:00015032160.019
cellular macromolecule catabolic processGO:00442652060.019
developmental maturationGO:00217001930.019
Fly
canonical wnt signaling pathwayGO:00600701300.019
synapse organizationGO:00508081250.019
gland developmentGO:00487323300.019
positive regulation of endocytosisGO:0045807420.019
Mouse
protein ubiquitinationGO:00165671710.019
positive regulation of purine nucleotide metabolic processGO:19005441140.019
divalent inorganic cation transportGO:00725111780.019
camera type eye developmentGO:00430102660.019
regulation of protein localizationGO:00328802310.018
cell recognitionGO:0008037830.018
divalent inorganic cation homeostasisGO:00725071380.018
neuron deathGO:00709971540.018
regulation of leukocyte differentiationGO:19021051590.018
neuromuscular processGO:0050905990.018
cell type specific apoptotic processGO:00972852680.018
neural tube closureGO:0001843900.018
cellular response to organonitrogen compoundGO:00714171450.018
response to growth factorGO:00708481980.018
skeletal system morphogenesisGO:00487052030.018
purine ribonucleoside catabolic processGO:00461302050.018
circulatory system processGO:00030131970.018
detection of external stimulusGO:0009581610.018
asymmetric neuroblast divisionGO:005505910.018
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.018
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.018
organonitrogen compound biosynthetic processGO:19015661920.018
establishment of protein localization to membraneGO:0090150540.018
regulation of homeostatic processGO:00328441820.018
neuron apoptotic processGO:00514021420.018
synaptic vesicle localizationGO:0097479590.018
Mouse
morphogenesis of embryonic epitheliumGO:00163311590.017
regulation of canonical wnt signaling pathwayGO:0060828820.017
retina development in camera type eyeGO:00600411190.017
regulation of protein catabolic processGO:00421761080.017
purine ribonucleotide catabolic processGO:00091542080.017
male gamete generationGO:00482322850.017
oocyte anterior posterior axis specificationGO:000731420.017
lipid localizationGO:00108761260.017
primary neural tube formationGO:0014020950.017
actin filament organizationGO:00070151130.017
negative regulation of phosphorylationGO:00423261660.017
renal system developmentGO:00720012250.017
guanosine containing compound catabolic processGO:19010691440.017
calcium ion transportGO:00068161590.017
negative regulation of neuron deathGO:1901215980.017
negative regulation of cellular component organizationGO:00511291940.017
regulation of cellular component sizeGO:00325351210.017
g protein coupled receptor signaling pathwayGO:00071862430.017
neuron migrationGO:00017641220.017
phagocytosisGO:0006909660.017
anion transmembrane transportGO:0098656710.017
cellular metal ion homeostasisGO:00068751510.016
chromatin organizationGO:00063252060.016
intracellular protein transportGO:00068862040.016
regulation of excitatory postsynaptic membrane potentialGO:0060079410.016
extracellular matrix organizationGO:00301981470.016
regulation of purine nucleotide metabolic processGO:19005421690.016
regulation of neuron apoptotic processGO:00435231220.016
oocyte axis specificationGO:000730920.016
regulation of transmembrane transportGO:00347621280.016
glucose metabolic processGO:0006006920.016
positive regulation of nucleotide metabolic processGO:00459811140.016
transmission of nerve impulseGO:0019226760.016
calcium ion homeostasisGO:00550741270.016
neural tube developmentGO:00219151600.016
microtubule cytoskeleton organizationGO:00002261570.016
cellular response to cytokine stimulusGO:00713451890.016
actin polymerization or depolymerizationGO:0008154540.016
cellular response to growth factor stimulusGO:00713631970.016
regulation of proteolysisGO:00301621640.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
cellular protein complex assemblyGO:00436231160.016
skeletal system developmentGO:00015013560.015
regulation of hormone levelsGO:00108172110.015
cell divisionGO:00513011200.015
gtp metabolic processGO:00460391440.015
positive regulation of transferase activityGO:00513471670.015
hemostasisGO:0007599780.015
reactive oxygen species metabolic processGO:0072593840.015
protein palmitoylationGO:0018345140.015
synaptic vesicle transportGO:0048489570.015
Mouse
cellular response to external stimulusGO:0071496880.015
detection of light stimulusGO:0009583250.015
positive regulation of protein kinase activityGO:00458601440.015
cellular response to dna damage stimulusGO:00069742070.015
regulation of gtp catabolic processGO:00331241130.015
epithelial tube formationGO:00721751300.015
positive regulation of dendrite developmentGO:1900006210.015
positive regulation of ion transportGO:0043270650.015
Mouse
regulation of cell migrationGO:00303342190.015
positive regulation of programmed cell deathGO:00430682180.015
glucose homeostasisGO:00425931280.015
protein processingGO:00164851630.015
positive regulation of rho gtpase activityGO:0032321410.015
negative regulation of lymphocyte activationGO:0051250910.015
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.015
response to acid chemicalGO:00011011110.014
positive regulation of mapk cascadeGO:00434101700.014
i kappab kinase nf kappab signalingGO:0007249850.014
inflammatory responseGO:00069542440.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
myeloid cell homeostasisGO:00022621140.014
positive regulation of hydrolase activityGO:00513451480.014
regulation of sequence specific dna binding transcription factor activityGO:00510901060.014
engulfment of apoptotic cellGO:004365230.014
negative regulation of cellular amine metabolic processGO:003323910.014
lung developmentGO:00303241640.014
mitotic cell cycle processGO:19030471590.014
action potentialGO:0001508780.014
regulation of protein serine threonine kinase activityGO:00719001570.014
anatomical structure homeostasisGO:00602491450.014
stem cell proliferationGO:00720891170.014
coagulationGO:0050817780.014
tube formationGO:00351481400.014
regionalizationGO:00030023370.014
cellular response to molecule of bacterial originGO:0071219830.014
organelle assemblyGO:00709251770.014
embryonic organ morphogenesisGO:00485622760.014
hexose metabolic processGO:0019318980.014
dephosphorylationGO:00163111290.014
protein maturationGO:00516041760.014
fat cell differentiationGO:00454441600.014
cellular protein catabolic processGO:00442571550.014
establishment of organelle localizationGO:00516561220.014
Mouse
neurotransmitter transportGO:0006836760.014
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.014
antimicrobial peptide biosynthetic processGO:000277720.014
regulation of wnt signaling pathwayGO:00301111230.014
monosaccharide metabolic processGO:00059961060.014
regulation of actin cytoskeleton organizationGO:0032956840.013
male gonad developmentGO:0008584880.013
neuron projection extensionGO:1990138640.013
embryonic epithelial tube formationGO:00018381300.013
peptidyl tyrosine modificationGO:00182121450.013
regulation of mitotic cell cycleGO:00073461260.013
neural tube formationGO:00018411080.013
blood vessel morphogenesisGO:00485142850.013
positive regulation of cellular catabolic processGO:00313311480.013
regulation of response to woundingGO:19030341890.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
exocytosisGO:00068871210.013
Mouse
bone developmentGO:00603481200.013
cell substrate adhesionGO:00315891300.013
positive regulation of leukocyte differentiationGO:1902107860.013
germ cell developmentGO:00072811850.013
regulation of synaptic vesicle transportGO:1902803130.013
Mouse
methylationGO:00322591340.013
connective tissue developmentGO:00614481790.013
carboxylic acid transportGO:00469421000.013
regulation of rho protein signal transductionGO:0035023710.013
modification dependent protein catabolic processGO:00199411330.013
cellular response to organic cyclic compoundGO:0071407870.013
tube closureGO:0060606910.013
establishment of vesicle localizationGO:0051650810.013
Mouse
regulation of cell cycle processGO:00105641600.012
muscle contractionGO:00069361010.012
extracellular structure organizationGO:00430621480.012
regulation of defense responseGO:00313472330.012
central nervous system neuron differentiationGO:00219531620.012
mesodermal cell migrationGO:000807840.012
negative regulation of protein modification processGO:00314001630.012
forebrain generation of neuronsGO:0021872630.012
regulation of establishment of protein localizationGO:00702011810.012
oxidation reduction processGO:00551143420.012
regulation of neurotransmitter levelsGO:0001505870.012
Mouse
positive regulation of nucleoside metabolic processGO:0045979910.012
response to extracellular stimulusGO:00099911270.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
regulation of nucleoside metabolic processGO:00091181300.012
mitotic cytokinesisGO:000028140.012
negative regulation of wnt signaling pathwayGO:0030178730.012
positive regulation of synapse assemblyGO:0051965180.012
Mouse Rat
positive regulation of cytokine productionGO:00018191740.012
regulation of nucleotide catabolic processGO:00308111220.012
interleukin 8 productionGO:003263740.012
positive regulation of cell activationGO:00508671580.012
nucleocytoplasmic transportGO:00069131390.012
cellular lipid metabolic processGO:00442553230.012
regulation of muscle system processGO:0090257800.012
positive regulation of apoptotic processGO:00430652170.012
positive regulation of gtp catabolic processGO:0033126850.012
positive regulation of cellular component biogenesisGO:0044089940.012
Mouse Rat
positive regulation of secretionGO:00510471300.012
Mouse
positive regulation of gtpase activityGO:0043547850.012
negative regulation of cell motilityGO:2000146610.012
learning or memoryGO:00076111480.012
Mouse
carbohydrate homeostasisGO:00335001280.012
urogenital system developmentGO:00016552610.012
positive regulation of actin filament polymerizationGO:0030838260.011
protein polymerizationGO:0051258570.011
regulation of cell growthGO:0001558910.011
vesicle organizationGO:0016050600.011
wound healingGO:00420601570.011
notch signaling pathwayGO:0007219710.011
negative regulation of cell activationGO:00508661110.011
glycoprotein biosynthetic processGO:0009101890.011
cellular response to biotic stimulusGO:0071216920.011
oocyte constructionGO:000730820.011
development of primary female sexual characteristicsGO:0046545730.011
regulation of actin filament based processGO:0032970990.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
regulation of system processGO:00440572000.011
multicellular organismal response to stressGO:0033555620.011
positive regulation of defense responseGO:00313491240.011
lipid transportGO:0006869980.011
positive regulation of t cell activationGO:00508701010.011
myeloid leukocyte differentiationGO:00025731190.011
second messenger mediated signalingGO:0019932730.011
regulation of purine nucleotide catabolic processGO:00331211220.011
cardiac muscle tissue developmentGO:00487381300.011
regulation of apoptotic signaling pathwayGO:20012331970.011
vesicle localizationGO:0051648860.011
Mouse
regulation of cellular response to stressGO:00801351590.011
negative regulation of cell migrationGO:0030336590.011
positive regulation of kinase activityGO:00336741550.011
response to inorganic substanceGO:0010035960.011
regulation of asymmetric cell divisionGO:000978640.011
myotube differentiationGO:00149021050.011
negative regulation of cytokine productionGO:0001818840.011
positive regulation of organelle organizationGO:00106381280.011
ubiquitin dependent protein catabolic processGO:00065111290.011
peptide secretionGO:00027901140.011
respiratory tube developmentGO:00303231670.011
leukocyte mediated immunityGO:00024431740.011
detection of abiotic stimulusGO:0009582600.011
organic acid transportGO:00158491010.011
hindbrain developmentGO:00309021280.011
regulation of cell substrate adhesionGO:0010810730.011
protein targetingGO:00066051430.011
cell junction organizationGO:0034330770.010
glycoprotein metabolic processGO:00091001160.010
purine nucleoside triphosphate catabolic processGO:00091462030.010
regulation of neuron deathGO:19012141340.010
organic hydroxy compound metabolic processGO:19016152030.010
response to peptideGO:19016521360.010
lipid biosynthetic processGO:00086101790.010
regulation of interleukin 8 productionGO:003267730.010
carbohydrate biosynthetic processGO:0016051740.010
negative regulation of growthGO:0045926990.010
defense response to other organismGO:00985421970.010
regulation of nucleotide metabolic processGO:00061401690.010
regulation of cytoplasmic transportGO:19036491120.010
regulation of protein transportGO:00512231630.010
histone modificationGO:00165701590.010
sensory perception of mechanical stimulusGO:00509541070.010
smoothened signaling pathwayGO:00072241050.010
ribonucleoside monophosphate metabolic processGO:0009161800.010
embryonic skeletal system morphogenesisGO:0048704910.010
morphogenesis of a branching epitheliumGO:00611381930.010
organelle fissionGO:00482851700.010
regulation of organ morphogenesisGO:20000271440.010
asymmetric stem cell divisionGO:009872230.010
response to peptide hormoneGO:00434341270.010
negative regulation of transferase activityGO:0051348850.010
epithelial cell proliferationGO:00506731740.010
negative regulation of synaptic transmission glutamatergicGO:005196740.010
regulation of myeloid cell differentiationGO:0045637960.010
skeletal muscle organ developmentGO:00605381630.010
regulation of extent of cell growthGO:0061387520.010
modification dependent macromolecule catabolic processGO:00436321330.010
cellular carbohydrate metabolic processGO:00442621190.010
regulation of cell adhesionGO:00301551540.010

Nlgn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
disease of metabolismDOID:001466700.014
central nervous system diseaseDOID:33100.012
neuropathyDOID:87000.012
musculoskeletal system diseaseDOID:1700.011
connective tissue diseaseDOID:6500.011