Mus musculus

168 known processes

Nlgn3

neuroligin 3

(Aliases: NL3,A230085M13Rik,HNL3)

Nlgn3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dendrite developmentGO:00163581150.235
regulation of neuron projection developmentGO:00109751690.175
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711330.146
Mouse
synaptic transmissionGO:00072683290.133
embryonic organ morphogenesisGO:00485622760.118
regulation of glutamate receptor signaling pathwayGO:1900449160.111
axonogenesisGO:00074092740.106
Rat
regulation of cell projection organizationGO:00313442060.098
rho protein signal transductionGO:0007266320.091
ion transmembrane transportGO:00342203610.086
glutamate receptor signaling pathwayGO:0007215350.085
regulation of cell morphogenesis involved in differentiationGO:00107691510.076
inorganic cation transmembrane transportGO:00986622070.076
inorganic ion transmembrane transportGO:00986602340.073
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activityGO:2000311110.071
positive regulation of nervous system developmentGO:00519622210.064
Mouse Rat
regulation of membrane potentialGO:00423911920.064
positive regulation of cell developmentGO:00107202370.061
chemotaxisGO:00069352470.060
skeletal system developmentGO:00015013560.058
microtubule based processGO:00070172360.058
negative regulation of cell proliferationGO:00082852960.057
forebrain developmentGO:00309003020.057
synapse organizationGO:00508081250.056
regulation of dendritic spine morphogenesisGO:0061001170.055
protein localization to membraneGO:00726571080.055
Mouse
central nervous system neuron differentiationGO:00219531620.054
regulation of neuron differentiationGO:00456642810.054
response to organonitrogen compoundGO:00102432460.054
cell fate commitmentGO:00451652100.054
locomotory behaviorGO:00076261950.053
Mouse Fly
regionalizationGO:00030023370.053
learningGO:0007612980.052
embryonic skeletal system developmentGO:00487061200.052
transmembrane transportGO:00550854120.052
ras protein signal transductionGO:0007265770.051
cellular amino acid metabolic processGO:00065201030.050
adult behaviorGO:00305341350.049
Human Fly
negative regulation of cell developmentGO:00107211690.049
regulation of cellular amine metabolic processGO:0033238200.048
negative regulation of nervous system developmentGO:00519611560.048
compound eye developmentGO:004874910.048
cognitionGO:00508901490.047
membrane depolarizationGO:0051899640.047
neuromuscular processGO:0050905990.047
Mouse
camera type eye developmentGO:00430102660.046
dendritic spine developmentGO:0060996300.046
negative regulation of cellular component organizationGO:00511291940.045
regulation of ion transmembrane transporter activityGO:0032412540.044
regulation of organelle organizationGO:00330432890.044
regulation of hydrolase activityGO:00513362460.043
cellular homeostasisGO:00197252400.043
cell adhesionGO:00071553290.042
Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.041
regulation of cellular amino acid metabolic processGO:000652150.041
cellular ketone metabolic processGO:0042180840.040
regulation of system processGO:00440572000.039
regulation of cellular ketone metabolic processGO:0010565660.038
lateral inhibitionGO:004633110.038
central nervous system neuron developmentGO:0021954670.038
negative regulation of cellular amino acid metabolic processGO:004576300.037
cellular amine metabolic processGO:0044106440.036
regulation of nucleotide metabolic processGO:00061401690.036
developmental maturationGO:00217001930.035
Fly
axon guidanceGO:00074111410.034
sensory organ morphogenesisGO:00905962420.033
regulation of excitatory postsynaptic membrane potentialGO:0060079410.032
regulation of cellular catabolic processGO:00313292420.032
endocytosisGO:00068971680.031
Mouse Rat
skeletal system morphogenesisGO:00487052030.030
microtubule cytoskeleton organizationGO:00002261570.030
neuroblast division in subventricular zoneGO:002184920.030
synapse maturationGO:0060074140.030
Fly
regulation of dendritic spine developmentGO:0060998220.030
actin cytoskeleton organizationGO:00300362200.030
negative regulation of cellular amine metabolic processGO:003323910.029
protein modification by small protein conjugationGO:00324461870.029
cation transmembrane transportGO:00986552660.029
nitrogen compound transportGO:00717052710.029
regulation of synaptic transmission glutamatergicGO:0051966190.029
neuron neuron synaptic transmissionGO:0007270690.029
small gtpase mediated signal transductionGO:0007264970.028
connective tissue developmentGO:00614481790.028
skin developmentGO:00435882200.028
cation transportGO:00068123990.028
developmental growth involved in morphogenesisGO:00605601380.028
Rat
intracellular protein transportGO:00068862040.027
single organism cell adhesionGO:00986021560.027
Mouse Rat
gonad developmentGO:00084061410.027
development of primary sexual characteristicsGO:00451371430.026
purine nucleoside triphosphate catabolic processGO:00091462030.026
negative regulation of synapse maturationGO:200029720.026
gtp metabolic processGO:00460391440.025
mapk cascadeGO:00001652810.025
peptidyl amino acid modificationGO:00181933360.025
purine ribonucleotide metabolic processGO:00091502900.025
divalent metal ion transportGO:00708381720.025
oxidation reduction processGO:00551143420.025
organelle assemblyGO:00709251770.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of synaptic plasticityGO:0048167870.025
protein ubiquitinationGO:00165671710.025
regulation of purine nucleotide metabolic processGO:19005421690.024
divalent inorganic cation transportGO:00725111780.024
retina development in camera type eyeGO:00600411190.024
neuron projection guidanceGO:00974851410.024
regulation of transporter activityGO:0032409570.024
canonical wnt signaling pathwayGO:00600701300.023
regulation of terminal button organizationGO:200033110.023
cellular response to organonitrogen compoundGO:00714171450.023
regulation of rho gtpase activityGO:0032319580.022
regulation of kinase activityGO:00435492490.022
maternal determination of anterior posterior axis embryoGO:000835820.022
regulation of postsynaptic membrane potentialGO:0060078480.022
germ cell developmentGO:00072811850.022
negative regulation of protein metabolic processGO:00512482820.022
wnt signaling pathwayGO:00160551880.022
dorsal ventral axon guidanceGO:003356330.022
regulation of purine nucleotide catabolic processGO:00331211220.022
metencephalon developmentGO:0022037890.022
protein targetingGO:00066051430.021
learning or memoryGO:00076111480.021
sensory perception of mechanical stimulusGO:00509541070.021
sensory perceptionGO:00076002450.021
Mouse
regulation of organ morphogenesisGO:20000271440.021
positive regulation of organelle organizationGO:00106381280.021
leukocyte differentiationGO:00025213420.021
glial cell differentiationGO:00100011310.021
purine ribonucleoside catabolic processGO:00461302050.021
receptor localization to synapseGO:009712040.021
Mouse
neural tube developmentGO:00219151600.021
positive regulation of mapk cascadeGO:00434101700.021
cerebellum developmentGO:0021549770.021
gland developmentGO:00487323300.020
cartilage developmentGO:00512161400.020
glycosyl compound catabolic processGO:19016582060.020
regulation of cellular response to stressGO:00801351590.020
photoreceptor cell differentiationGO:0046530520.020
nucleobase containing small molecule metabolic processGO:00550863520.020
male gamete generationGO:00482322850.020
positive regulation of protein modification processGO:00314012990.020
sodium ion transmembrane transportGO:0035725490.020
negative regulation of neuron differentiationGO:00456651010.019
regulation of apoptotic signaling pathwayGO:20012331970.019
divalent inorganic cation homeostasisGO:00725071380.019
amine metabolic processGO:0009308450.019
spermatid differentiationGO:00485151150.019
regulation of long term synaptic depressionGO:190045230.019
calcium ion transportGO:00068161590.019
positive regulation of neuron projection developmentGO:0010976790.019
kidney developmentGO:00018222130.019
stem cell differentiationGO:00488632680.019
morphogenesis of a branching structureGO:00017632030.019
ribonucleoside triphosphate catabolic processGO:00092031990.019
response to organic cyclic compoundGO:00140701980.019
negative regulation of phosphorylationGO:00423261660.019
ribose phosphate metabolic processGO:00196932910.019
body fluid secretionGO:0007589530.019
glucose homeostasisGO:00425931280.019
regulation of n methyl d aspartate selective glutamate receptor activityGO:2000310100.019
regulation of cell motilityGO:20001452360.019
response to radiationGO:00093141650.019
response to acid chemicalGO:00011011110.019
directional locomotionGO:003305830.019
organic cyclic compound catabolic processGO:19013612950.018
oocyte anterior posterior axis specificationGO:000731420.018
protein modification by small protein conjugation or removalGO:00706472070.018
negative regulation of phosphate metabolic processGO:00459361840.018
negative regulation of cellular protein metabolic processGO:00322692470.018
t cell activationGO:00421102890.018
spermatogenesisGO:00072832840.018
lung developmentGO:00303241640.018
regulation of proteolysisGO:00301621640.018
positive regulation of membrane potentialGO:0045838150.018
ribonucleotide metabolic processGO:00092592910.018
heterocycle catabolic processGO:00467002800.018
appendage morphogenesisGO:00351071490.018
myeloid dendritic cell chemotaxisGO:000240820.018
lateral line system developmentGO:004892510.018
detection of mechanical stimulus involved in sensory perception of painGO:005096640.018
peptide secretionGO:00027901140.018
dendritic spine organizationGO:0097061260.018
mitotic cell cycleGO:00002781950.018
regulation of nucleotide catabolic processGO:00308111220.018
positive regulation of hydrolase activityGO:00513451480.018
establishment of protein localization to membraneGO:0090150540.017
neuromuscular process controlling balanceGO:0050885590.017
Mouse
posttranscriptional regulation of gene expressionGO:00106081550.017
regulation of mitotic cell cycleGO:00073461260.017
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.017
regulation of body fluid levelsGO:00508781620.017
apoptotic signaling pathwayGO:00971903060.017
regulation of cell adhesionGO:00301551540.017
detection of mechanical stimulusGO:0050982270.017
defecationGO:003042110.017
epithelial tube morphogenesisGO:00605623030.017
regulation of epithelial cell proliferationGO:00506781410.017
telencephalon developmentGO:00215371860.017
dephosphorylationGO:00163111290.017
positive regulation of cellular amine metabolic processGO:003324050.017
primary neural tube formationGO:0014020950.017
memoryGO:0007613580.017
regulation of synaptic growth at neuromuscular junctionGO:000858240.017
positive regulation of cell deathGO:00109422240.017
nucleotide metabolic processGO:00091173320.016
ear morphogenesisGO:00424711180.016
regulation of gtp catabolic processGO:00331241130.016
morphogenesis of embryonic epitheliumGO:00163311590.016
organophosphate catabolic processGO:00464342320.016
cell divisionGO:00513011200.016
ribonucleoside catabolic processGO:00424542060.016
protein localization to synapseGO:0035418110.016
Mouse
gtp catabolic processGO:00061841430.016
mitotic cell cycle processGO:19030471590.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.016
positive regulation of ras gtpase activityGO:0032320650.016
pole plasm assemblyGO:000731520.016
regulation of cell cycleGO:00517262810.016
cerebral cortex developmentGO:0021987860.016
bone developmentGO:00603481200.016
olfactory bulb axon guidanceGO:007167810.016
glycosyl compound metabolic processGO:19016572460.016
nucleoside phosphate catabolic processGO:19012922220.016
ribonucleotide catabolic processGO:00092612080.016
regulation of canonical wnt signaling pathwayGO:0060828820.016
response to inorganic substanceGO:0010035960.016
mitochondrion organizationGO:00070051340.016
ribonucleoside metabolic processGO:00091192450.016
cellular response to hexose stimulusGO:0071331470.015
purine nucleoside catabolic processGO:00061522050.015
regulation of protein complex assemblyGO:0043254830.015
cellular response to growth factor stimulusGO:00713631970.015
establishment of organelle localizationGO:00516561220.015
Mouse
circadian rhythmGO:00076231140.015
regulation of transferase activityGO:00513382630.015
negative regulation of intracellular signal transductionGO:19025321670.015
lymphocyte differentiationGO:00300982420.015
membrane organizationGO:00610242450.015
positive regulation of nucleotide metabolic processGO:00459811140.015
protein maturationGO:00516041760.015
membrane hyperpolarizationGO:0060081210.015
carbohydrate homeostasisGO:00335001280.015
asymmetric neuroblast divisionGO:005505910.015
positive regulation of neuron projection regenerationGO:007057220.015
cation homeostasisGO:00550802120.015
positive regulation of purine nucleotide metabolic processGO:19005441140.015
cellular chemical homeostasisGO:00550822150.015
regulation of cellular component biogenesisGO:00440871810.014
Mouse Rat
notch signaling pathwayGO:0007219710.014
negative regulation of wnt signaling pathwayGO:0030178730.014
oocyte constructionGO:000730820.014
regulation of hormone levelsGO:00108172110.014
nucleoside triphosphate metabolic processGO:00091412300.014
establishment or maintenance of cytoskeleton polarityGO:003095220.014
purine ribonucleotide catabolic processGO:00091542080.014
nucleocytoplasmic transportGO:00069131390.014
negative regulation of molecular functionGO:00440922580.014
positive regulation of protein phosphorylationGO:00019342420.014
ear developmentGO:00435832000.014
cellular response to monosaccharide stimulusGO:0071326470.014
sensory perception of soundGO:0007605970.014
sensory system developmentGO:004888030.014
neurotransmitter secretionGO:0007269620.014
Mouse
establishment of synaptic vesicle localizationGO:0097480570.014
Mouse
development of primary male sexual characteristicsGO:0046546880.014
negative regulation of dendrite developmentGO:200017190.014
cellular nitrogen compound catabolic processGO:00442702800.014
anion transportGO:00068201770.014
positive regulation of protein complex assemblyGO:0031334450.014
calcium ion transmembrane transportGO:0070588850.014
regulation of nucleoside metabolic processGO:00091181300.014
protein localization to organelleGO:00333651850.014
peptide hormone secretionGO:00300721090.014
regulation of cytoskeleton organizationGO:00514931220.013
nuclear divisionGO:00002801580.013
regulation of secretion by cellGO:19035302490.013
Mouse
nucleotide catabolic processGO:00091662170.013
nucleoside phosphate metabolic processGO:00067533380.013
positive regulation of cellular component biogenesisGO:0044089940.013
Mouse Rat
oocyte axis specificationGO:000730920.013
digestive system developmentGO:00551232000.013
neuron migrationGO:00017641220.013
photoreceptor cell developmentGO:0042461400.013
embryonic skeletal system morphogenesisGO:0048704910.013
regulation of neurotransmitter levelsGO:0001505870.013
Mouse
eye photoreceptor cell differentiationGO:0001754410.013
single organismal cell cell adhesionGO:00163371310.013
Mouse Rat
regulation of mapk cascadeGO:00434082480.013
stem cell developmentGO:00488642190.013
regulation of wnt signaling pathwayGO:00301111230.013
regulation of neuronal synaptic plasticityGO:0048168300.013
adult locomotory behaviorGO:0008344910.013
Fly
tube formationGO:00351481400.013
regulation of cell migrationGO:00303342190.013
positive regulation of gtp catabolic processGO:0033126850.013
regulation of peptide hormone secretionGO:0090276750.013
positive regulation of programmed cell deathGO:00430682180.013
negative regulation of inclusion body assemblyGO:009008410.013
cellular ion homeostasisGO:00068731650.013
regulation of protein kinase activityGO:00458592320.013
organonitrogen compound catabolic processGO:19015652640.013
epidermis developmentGO:00085441870.013
cilium morphogenesisGO:00602711020.013
regulation of extent of cell growthGO:0061387520.013
positive regulation of gtpase activityGO:0043547850.013
actin filament organizationGO:00070151130.013
rhythmic processGO:00485111740.013
morphogenesis of a polarized epitheliumGO:0001738370.013
body morphogenesisGO:0010171450.012
negative regulation of neuron projection developmentGO:0010977500.012
spermatid developmentGO:00072861080.012
formation of organ boundaryGO:001016010.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
nuclear transportGO:00511691390.012
organelle localizationGO:00516401790.012
Mouse
protein processingGO:00164851630.012
regulation of ras gtpase activityGO:0032318880.012
organonitrogen compound biosynthetic processGO:19015661920.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
respiratory tube developmentGO:00303231670.012
bone morphogenesisGO:0060349780.012
calcium mediated signaling using intracellular calcium sourceGO:003558430.012
limb developmentGO:00601731660.012
regulation of rho protein signal transductionGO:0035023710.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
regulation of establishment of protein localizationGO:00702011810.012
receptor mediated endocytosisGO:0006898510.012
Rat
regulation of peptide transportGO:0090087910.012
endomembrane system organizationGO:00102561470.012
Fly
purine containing compound metabolic processGO:00725213110.012
macromolecule catabolic processGO:00090572810.012
regulation of protein catabolic processGO:00421761080.012
embryonic epithelial tube formationGO:00018381300.012
synaptic transmission glutamatergicGO:0035249360.012
cellular component assembly involved in morphogenesisGO:00109271390.012
cell substrate adhesionGO:00315891300.012
jnk cascadeGO:0007254720.012
neural tube closureGO:0001843900.012
fat cell differentiationGO:00454441600.012
purine nucleoside metabolic processGO:00422782410.012
appendage developmentGO:00487361660.012
extracellular structure organizationGO:00430621480.012
maintenance of locationGO:0051235890.012
protein localization to plasma membraneGO:0072659570.012
energy derivation by oxidation of organic compoundsGO:0015980770.012
protein catabolic processGO:00301632210.012
female gamete generationGO:0007292740.012
sodium ion transportGO:0006814730.011
multicellular organismal homeostasisGO:00488711640.011
organic anion transportGO:00157111370.011
protein localization to nucleusGO:00345041210.011
nucleoside catabolic processGO:00091642060.011
positive regulation of cellular catabolic processGO:00313311480.011
negative regulation of synaptic transmission glutamatergicGO:005196740.011
cellular response to lipidGO:00713961450.011
inner ear morphogenesisGO:00424721010.011
epithelial tube formationGO:00721751300.011
small molecule biosynthetic processGO:00442831320.011
dendritic spine morphogenesisGO:0060997220.011
developmental cell growthGO:0048588840.011
Rat
organic acid transportGO:00158491010.011
myeloid cell differentiationGO:00300992330.011
wound healingGO:00420601570.011
organelle fissionGO:00482851700.011
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.011
actin filament bundle assemblyGO:0051017400.011
amide transportGO:00428861380.011
t cell differentiationGO:00302171740.011
keratinocyte developmentGO:0003334100.011
positive regulation of long term neuronal synaptic plasticityGO:004817030.011
neuron projection extensionGO:1990138640.011
Rat
hindbrain developmentGO:00309021280.011
regulation of ion transmembrane transportGO:00347651190.011
guanosine containing compound catabolic processGO:19010691440.011
chromatin organizationGO:00063252060.010
exploration behaviorGO:0035640210.010
Mouse
regulation of endocytosisGO:0030100690.010
Mouse
positive regulation of apoptotic processGO:00430652170.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.010
positive regulation of cell projection organizationGO:0031346950.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
tube closureGO:0060606910.010
multicellular organismal signalingGO:0035637910.010
limb morphogenesisGO:00351081490.010
positive regulation of protein kinase activityGO:00458601440.010
intracellular mrna localizationGO:000829840.010
protein importGO:00170381010.010
nucleoside triphosphate catabolic processGO:00091432050.010
mechanoreceptor differentiationGO:0042490670.010
negative regulation of phosphorus metabolic processGO:00105631840.010
regulation of protein localizationGO:00328802310.010
regulation of t cell proliferationGO:0042129920.010
b cell activationGO:00421131610.010
extracellular matrix organizationGO:00301981470.010
plasma membrane organizationGO:0007009900.010
regulation of long term neuronal synaptic plasticityGO:0048169190.010

Nlgn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.039
central nervous system diseaseDOID:33100.029
brain diseaseDOID:93600.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.016
sensory system diseaseDOID:005015500.015
epilepsy syndromeDOID:182600.014
electroclinical syndromeDOID:005070100.014
musculoskeletal system diseaseDOID:1700.011