Mus musculus

0 known processes

Lair1

leukocyte-associated Ig-like receptor 1

(Aliases: 5133400O11Rik,D7Bwg0421e,mLair-1,Lair-1,BB115266)

Lair1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mast cell activationGO:0033003210.930
cell surface pattern recognition receptor signaling pathwayGO:000275220.872
response to molecule of fungal originGO:000223840.740
purinergic nucleotide receptor signaling pathwayGO:003559030.710
negative regulation of immune system processGO:00026832090.631
detection of fungusGO:001604620.613
t cell activationGO:00421102890.590
defense response to other organismGO:00985421970.571
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558910.534
regulation of cell activationGO:00508652890.520
immune effector processGO:00022523210.517
cytokine productionGO:00018163190.508
detection of external biotic stimulusGO:009858190.505
myeloid leukocyte activationGO:0002274830.501
regulation of natural killer cell activationGO:0032814220.493
toll like receptor 9 signaling pathwayGO:003416260.488
leukocyte mediated immunityGO:00024431740.469
cation transportGO:00068123990.457
defense response to bacteriumGO:00427421190.445
cellular response to peptidoglycanGO:007122440.444
detection of biotic stimulusGO:0009595100.430
positive regulation of immune effector processGO:00026991070.421
leukocyte proliferationGO:00706611720.407
toll like receptor signaling pathwayGO:0002224380.406
regulation of lymphocyte activationGO:00512492400.378
reactive oxygen species metabolic processGO:0072593840.373
innate immune responseGO:00450871570.369
immune response regulating signaling pathwayGO:00027641250.363
regulation of leukocyte mediated immunityGO:00027031040.356
positive regulation of protein transportGO:0051222930.355
immune response regulating cell surface receptor signaling pathwayGO:0002768800.353
serotonin secretion involved in inflammatory responseGO:000244240.334
regulation of protein transportGO:00512231630.331
activation of innate immune responseGO:0002218560.328
regulation of innate immune responseGO:0045088910.318
regulation of toll like receptor 9 signaling pathwayGO:003416330.308
positive regulation of cytokine secretionGO:0050715410.302
cellular response to biotic stimulusGO:0071216920.300
protein secretionGO:00093061110.296
regulation of protein secretionGO:0050708820.287
detection of other organismGO:009854380.284
positive regulation of reactive oxygen species biosynthetic processGO:190342820.278
myeloid leukocyte mediated immunityGO:0002444420.278
cytoplasmic transportGO:00164822340.273
regulation of antigen receptor mediated signaling pathwayGO:0050854290.269
negative regulation of cell activationGO:00508661110.262
positive regulation of leukocyte mediated immunityGO:0002705700.259
regulation of cytokine productionGO:00018172660.259
activation of immune responseGO:00022531380.256
leukocyte degranulationGO:0043299270.255
immune response activating signal transductionGO:00027571160.253
regulation of intracellular transportGO:00323861590.250
membrane organizationGO:00610242450.248
regulation of leukocyte mediated cytotoxicityGO:0001910380.244
immune response activating cell surface receptor signaling pathwayGO:0002429720.243
reactive oxygen species biosynthetic processGO:190340980.239
serotonin secretionGO:000182080.235
positive regulation of secretion by cellGO:19035321140.230
innate immune response activating signal transductionGO:0002758500.229
positive regulation of defense responseGO:00313491240.229
regulation of reactive oxygen species biosynthetic processGO:190342620.218
regulation of protein localizationGO:00328802310.218
regulation of establishment of protein localizationGO:00702011810.216
cellular response to molecule of fungal originGO:007122620.215
regulation of secretionGO:00510462740.209
regulation of exocytosisGO:0017157610.202
regulation of cellular amino acid metabolic processGO:000652150.201
inflammatory responseGO:00069542440.197
regulation of secretion by cellGO:19035302490.197
positive regulation of intracellular transportGO:0032388700.193
leukocyte activation involved in immune responseGO:00023661260.193
cellular amine metabolic processGO:0044106440.190
regulation of interleukin 6 productionGO:0032675550.188
natural killer cell activationGO:0030101440.187
regulation of lymphocyte proliferationGO:00506701170.186
mapk cascadeGO:00001652810.182
cytokine metabolic processGO:0042107710.182
positive regulation of interleukin 18 productionGO:003274120.178
stimulatory c type lectin receptor signaling pathwayGO:000222320.177
nitrogen compound transportGO:00717052710.176
reactive nitrogen species metabolic processGO:200105700.165
single organismal cell cell adhesionGO:00163371310.161
regulation of vesicle mediated transportGO:00606271390.159
detection of molecule of bacterial originGO:003249020.159
i kappab kinase nf kappab signalingGO:0007249850.159
myeloid cell differentiationGO:00300992330.159
regulation of cell migrationGO:00303342190.158
negative regulation of serotonin secretionGO:001406320.158
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.156
positive regulation of cytokine productionGO:00018191740.154
calcium mediated signalingGO:0019722460.154
regulation of defense responseGO:00313472330.152
tumor necrosis factor superfamily cytokine productionGO:0071706510.152
regulation of leukocyte proliferationGO:00706631210.148
g protein coupled receptor signaling pathwayGO:00071862430.147
positive regulation of secretionGO:00510471300.143
response to molecule of bacterial originGO:00022371430.142
positive regulation of cellular amine metabolic processGO:003324050.139
tumor necrosis factor productionGO:0032640500.139
regulation of tumor necrosis factor productionGO:0032680490.139
leukocyte mediated cytotoxicityGO:0001909620.138
lymphocyte proliferationGO:00466511640.135
second messenger mediated signalingGO:0019932730.134
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542520.132
toll like receptor 7 signaling pathwayGO:003415440.132
pattern recognition receptor signaling pathwayGO:0002221470.132
regulation of ion transportGO:00432692150.131
regulation of interferon gamma productionGO:0032649570.130
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.130
detection of stimulusGO:0051606840.129
positive regulation of protein secretionGO:0050714520.129
regulation of t cell activationGO:00508631700.128
cellular amino acid metabolic processGO:00065201030.127
mast cell activationGO:0045576270.126
amine metabolic processGO:0009308450.126
serotonin production involved in inflammatory responseGO:000235140.126
detection of yeastGO:000187920.125
cytokine secretionGO:0050663720.124
innate immune response activating cell surface receptor signaling pathwayGO:000222040.124
positive regulation of reactive oxygen species metabolic processGO:2000379110.124
regulation of kinase activityGO:00435492490.122
negative t cell selectionGO:0043383130.120
cell activation involved in immune responseGO:00022631260.120
mast cell degranulationGO:0043303190.120
cellular response to lipopolysaccharideGO:0071222770.119
negative regulation of mast cell degranulationGO:004330540.117
positive regulation of calcium mediated signalingGO:0050850150.111
lysosome localizationGO:0032418200.111
myeloid cell activation involved in immune responseGO:0002275340.110
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.110
regulation of protein kinase activityGO:00458592320.110
regulation of cytokine biosynthetic processGO:0042035590.110
cellular response to molecule of bacterial originGO:0071219830.107
mast cell mediated immunityGO:0002448200.107
response to lipopolysaccharideGO:00324961280.104
positive regulation of protein modification processGO:00314012990.101
t cell proliferationGO:00420981200.101
platelet activationGO:0030168400.097
negative regulation of immune effector processGO:0002698550.097
positive regulation by symbiont of host defense responseGO:005250910.097
regulation of cytokine secretionGO:0050707610.096
regulation of cellular ketone metabolic processGO:0010565660.096
regulation of phagocytosisGO:0050764330.094
cellular homeostasisGO:00197252400.093
positive regulation of innate immune responseGO:0045089800.093
positive regulation of cellular amino acid metabolic processGO:004576430.091
blood coagulationGO:0007596760.088
production of molecular mediator involved in inflammatory responseGO:0002532210.087
single organism cell adhesionGO:00986021560.086
leukocyte differentiationGO:00025213420.086
regulation of cell motilityGO:20001452360.085
positive regulation of toll like receptor 9 signaling pathwayGO:003416520.085
cellular ion homeostasisGO:00068731650.084
negative regulation of leukocyte mediated immunityGO:0002704290.084
negative regulation of phosphorylationGO:00423261660.084
regulation of protein serine threonine kinase activityGO:00719001570.083
regulation of t cell proliferationGO:0042129920.083
positive regulation of lymphocyte mediated immunityGO:0002708620.082
regulation of mast cell degranulationGO:0043304160.082
serotonin transportGO:0006837110.081
regulation of multi organism processGO:00439001110.081
intracellular protein transportGO:00068862040.080
detection of bacteriumGO:001604570.080
regulation of transferase activityGO:00513382630.079
positive regulation of endocytosisGO:0045807420.076
phagocytosisGO:0006909660.075
immunoglobulin transcytosis in epithelial cellsGO:000241420.074
intestinal epithelial structure maintenanceGO:006072940.074
exocytosisGO:00068871210.073
protein targetingGO:00066051430.072
interleukin 18 productionGO:003262140.071
regulation of cellular amine metabolic processGO:0033238200.071
t cell receptor signaling pathwayGO:0050852460.070
positive regulation of interferon alpha biosynthetic processGO:004535610.070
positive regulation of mast cell degranulationGO:0043306100.070
negative regulation of phosphorus metabolic processGO:00105631840.070
endocytosisGO:00068971680.069
positive regulation by symbiont of defense related host nitric oxide productionGO:005234710.069
unsaturated fatty acid metabolic processGO:0033559310.068
regulation of inflammatory responseGO:00507271470.068
positive regulation of lymphocyte proliferationGO:0050671700.067
negative regulation of phosphate metabolic processGO:00459361840.067
positive regulation of transferase activityGO:00513471670.066
mast cell activation involved in immune responseGO:0002279200.066
negative regulation of protein metabolic processGO:00512482820.066
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.065
multicellular organismal homeostasisGO:00488711640.065
regulation of body fluid levelsGO:00508781620.065
response to hostGO:007513630.065
organic hydroxy compound transportGO:0015850930.065
regulation of serotonin secretionGO:001406230.064
regulation of b cell proliferationGO:0030888390.063
protein localization to organelleGO:00333651850.063
establishment or maintenance of cytoskeleton polarityGO:003095220.062
tumor necrosis factor biosynthetic processGO:0042533100.061
coagulationGO:0050817780.061
cellular response to drugGO:0035690150.061
positive regulation of hemostasisGO:1900048100.060
sequestering of metal ionGO:0051238190.060
negative regulation of cellular component organizationGO:00511291940.060
peptidyl amino acid modificationGO:00181933360.060
cell chemotaxisGO:0060326810.059
maintenance of locationGO:0051235890.059
induction by symbiont of host immune responseGO:005255910.059
regulation of natural killer cell mediated immunityGO:0002715190.058
positive regulation of natural killer cell mediated immunityGO:0002717160.058
divalent inorganic cation transportGO:00725111780.057
antigen receptor mediated signaling pathwayGO:0050851640.057
leukotriene metabolic processGO:000669170.057
regulation of regulated secretory pathwayGO:1903305200.057
negative regulation of cellular protein metabolic processGO:00322692470.057
blood vessel morphogenesisGO:00485142850.056
toxin catabolic processGO:000940710.055
positive regulation of regulated secretory pathwayGO:1903307100.055
cellular metal ion homeostasisGO:00068751510.055
cellular ketone metabolic processGO:0042180840.054
regulation of chemokine productionGO:0032642300.054
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.054
protein import into nucleusGO:0006606950.054
cellular response to lipidGO:00713961450.053
cellular lipid metabolic processGO:00442553230.052
positive regulation of interferon gamma productionGO:0032729390.052
regulation of erk1 and erk2 cascadeGO:0070372710.052
regulation of calcium mediated signalingGO:0050848190.052
cell adhesionGO:00071553290.052
regulation of cellular response to stressGO:00801351590.051
inorganic cation transmembrane transportGO:00986622070.051
positive regulation of kinase activityGO:00336741550.051
activation of mapk activityGO:0000187590.051
macrophage activationGO:0042116270.051
negative regulation of intracellular signal transductionGO:19025321670.049
regulation of reactive oxygen species metabolic processGO:2000377400.049
positive regulation of cell killingGO:0031343330.049
induction by organism of defense response of other organism involved in symbiotic interactionGO:005225110.049
positive regulation of tumor necrosis factor productionGO:0032760300.049
unsaturated fatty acid biosynthetic processGO:0006636150.049
regulation of granulocyte macrophage colony stimulating factor productionGO:003264530.049
thymic t cell selectionGO:0045061220.048
cellular response to organonitrogen compoundGO:00714171450.048
leukocyte migrationGO:00509001240.048
nitric oxide biosynthetic processGO:0006809250.048
granulocyte macrophage colony stimulating factor productionGO:003260430.048
regulation of cell killingGO:0031341400.048
purinergic receptor signaling pathwayGO:003558770.048
positive regulation of coagulationGO:0050820130.047
positive regulation of phagocytosisGO:0050766260.047
tissue homeostasisGO:00018941150.047
ras protein signal transductionGO:0007265770.047
detection of peptidoglycanGO:003249910.046
metal ion homeostasisGO:00550651890.046
organelle localizationGO:00516401790.046
cellular chemical homeostasisGO:00550822150.046
regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542320.045
protein importGO:00170381010.045
protein ubiquitinationGO:00165671710.045
regulation of tumor necrosis factor biosynthetic processGO:0042534100.045
negative regulation of mapk cascadeGO:0043409650.045
production of molecular mediator of immune responseGO:00024401030.044
cytokine biosynthetic processGO:0042089680.044
regulation of mapk cascadeGO:00434082480.044
response to defense related nitric oxide production by other organism involved in symbiotic interactionGO:005255120.044
nitric oxide metabolic processGO:0046209250.044
positive regulation of leukocyte degranulationGO:0043302100.043
natural killer cell mediated immunityGO:0002228290.043
response to host immune responseGO:005257230.043
small molecule biosynthetic processGO:00442831320.043
type i interferon productionGO:0032606290.043
sequestering of calcium ionGO:0051208180.043
positive regulation of lymphocyte activationGO:00512511400.043
interferon beta biosynthetic processGO:004535040.042
positive regulation of t cell extravasationGO:200040920.042
nuclear importGO:0051170950.042
induction by organism of immune response of other organism involved in symbiotic interactionGO:005255810.042
natural killer cell mediated cytotoxicityGO:0042267290.042
regulation of t cell costimulationGO:200052320.042
protein modification by small protein conjugation or removalGO:00706472070.041
chemotaxisGO:00069352470.041
divalent metal ion transportGO:00708381720.041
cation transmembrane transportGO:00986552660.041
positive regulation of interferon alpha productionGO:003272740.041
regulation of jnk cascadeGO:0046328620.041
lipid biosynthetic processGO:00086101790.041
cell recognitionGO:0008037830.040
regulation of map kinase activityGO:00434051200.040
wound healingGO:00420601570.040
regulated secretory pathwayGO:0045055320.040
alpha beta t cell activationGO:0046631910.039
positive regulation of homeostatic processGO:0032846640.039
erk1 and erk2 cascadeGO:0070371770.039
t cell differentiation in thymusGO:0033077770.039
anatomical structure homeostasisGO:00602491450.039
stress activated protein kinase signaling cascadeGO:0031098810.038
regulation of response to woundingGO:19030341890.038
microtubule based processGO:00070172360.038
regulation of myeloid leukocyte mediated immunityGO:0002886250.037
positive regulation of cell activationGO:00508671580.037
nucleocytoplasmic transportGO:00069131390.037
positive regulation of tumor necrosis factor biosynthetic processGO:004253580.036
adaptive immune responseGO:00022501550.036
regulation of nitric oxide biosynthetic processGO:0045428180.036
interferon gamma productionGO:0032609670.036
regulation of homeostatic processGO:00328441820.036
cellular divalent inorganic cation homeostasisGO:00725031270.036
cellular response to cytokine stimulusGO:00713451890.036
regulation of organelle organizationGO:00330432890.035
embryonic placenta developmentGO:0001892980.035
positive regulation of response to woundingGO:1903036660.035
regulation of mast cell activation involved in immune responseGO:0033006170.035
regulation of endocytosisGO:0030100690.035
lymphocyte mediated immunityGO:00024491390.035
transmembrane transportGO:00550854120.035
regulation of ion homeostasisGO:2000021640.035
regulation of lymphocyte mediated immunityGO:0002706840.034
response to defense related host nitric oxide productionGO:005256520.034
hemostasisGO:0007599780.034
protein localization to nucleusGO:00345041210.034
positive regulation of mast cell activationGO:0033005120.034
regulation of coagulationGO:0050818310.033
ossificationGO:00015032160.033
neutrophil chemotaxisGO:0030593360.033
nuclear transportGO:00511691390.033
neutrophil mediated immunityGO:0002446190.032
regulation of vesicle fusionGO:003133860.032
positive regulation of protein kinase activityGO:00458601440.032
positive regulation of erk1 and erk2 cascadeGO:0070374470.032
positive regulation of leukocyte proliferationGO:0070665730.032
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.032
small gtpase mediated signal transductionGO:0007264970.032
negative regulation of lymphocyte proliferationGO:0050672450.032
regulation of adaptive immune responseGO:0002819900.032
monocarboxylic acid biosynthetic processGO:0072330610.032
positive regulation of alpha beta t cell activationGO:0046635390.032
regulation of interleukin 18 productionGO:003266130.032
superoxide metabolic processGO:0006801270.031
t cell differentiationGO:00302171740.031
defense response to gram positive bacteriumGO:0050830500.031
negative regulation of phagocytosisGO:005076540.031
positive regulation of cell migrationGO:00303351090.031
sensory perceptionGO:00076002450.031
placenta developmentGO:00018901400.031
kidney developmentGO:00018222130.031
interleukin 6 productionGO:0032635580.031
protein modification by small protein conjugationGO:00324461870.030
response to bacterial lipoproteinGO:003249340.030
dna metabolic processGO:00062593030.030
nucleobase containing small molecule metabolic processGO:00550863520.030
inorganic ion transmembrane transportGO:00986602340.030
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.030
positive regulation of cytokine biosynthetic processGO:0042108400.029
cation homeostasisGO:00550802120.029
ameboidal type cell migrationGO:00016671280.029
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.029
oxidation reduction processGO:00551143420.029
positive regulation of stress activated mapk cascadeGO:0032874480.028
negative regulation of regulated secretory pathwayGO:190330670.028
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.028
negative regulation of protein modification processGO:00314001630.028
positive regulation of granulocyte macrophage colony stimulating factor productionGO:003272530.028
regulation of leukocyte differentiationGO:19021051590.028
purine ribonucleoside triphosphate metabolic processGO:00092052200.028
cytosolic calcium ion homeostasisGO:0051480700.028
response to host defensesGO:005220030.028
regulation of b cell activationGO:0050864810.028
homeostasis of number of cellsGO:00488722100.028
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.028
organic cyclic compound catabolic processGO:19013612950.027
nucleoside catabolic processGO:00091642060.027
modulation by organism of immune response of other organism involved in symbiotic interactionGO:005255210.027
erythrocyte differentiationGO:0030218880.027
ribonucleoside metabolic processGO:00091192450.027
ribose phosphate metabolic processGO:00196932910.027
peptidyl tyrosine modificationGO:00182121450.027
positive regulation of interferon beta biosynthetic processGO:004535930.027
modulation by organism of defense response of other organism involved in symbiotic interactionGO:005225510.027
lymphocyte differentiationGO:00300982420.026
detection of lipopolysaccharideGO:003249710.026
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interactionGO:005234510.026
jnk cascadeGO:0007254720.026
negative regulation of interleukin 23 productionGO:003270710.026
regulation of hemostasisGO:1900046280.026
germ cell developmentGO:00072811850.026
neutrophil degranulationGO:004331260.026
b cell activation involved in immune responseGO:0002312500.026
positive regulation of nervous system developmentGO:00519622210.026
b cell activationGO:00421131610.026
positive regulation of nitric oxide biosynthetic processGO:0045429140.025
regulation of osteoclast differentiationGO:0045670360.025
response to growth factorGO:00708481980.025
regulation of leukocyte degranulationGO:0043300200.025
carboxylic acid biosynthetic processGO:0046394860.025
positive regulation of cell motilityGO:20001471160.025
regulation of metal ion transportGO:00109591060.025
renal system developmentGO:00720012250.025
peptidyl serine phosphorylationGO:0018105740.025
monocarboxylic acid metabolic processGO:00327871910.025
regulation of natural killer cell mediated cytotoxicityGO:0042269190.024
cd8 positive alpha beta t cell extravasationGO:003569730.024
response to defenses of other organism involved in symbiotic interactionGO:005217330.024
gtp catabolic processGO:00061841430.024
cellular calcium ion homeostasisGO:00068741190.024
regulation of blood coagulationGO:0030193280.024
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043420.024
phagocytosis recognitionGO:0006910120.024
regulation of t cell receptor signaling pathwayGO:0050856210.024
negative regulation of hypersensitivityGO:000288430.024
positive regulation of t cell activationGO:00508701010.024
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.024
negative regulation of erk1 and erk2 cascadeGO:0070373210.024
regulation of t cell extravasationGO:200040730.024
monoamine transportGO:0015844330.024
positive regulation of jnk cascadeGO:0046330460.024
negative regulation of adaptive immune responseGO:0002820250.024
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.023
t cell mediated immunityGO:0002456500.023
negative regulation of lymphocyte activationGO:0051250910.023
negative regulation of synapse assemblyGO:005196430.023
positive regulation of mhc class ii biosynthetic processGO:004534840.023
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.023
apoptotic signaling pathwayGO:00971903060.023
spermatogenesisGO:00072832840.023
regulation of alpha beta t cell activationGO:0046634530.023
regulation of calcium ion transportGO:0051924690.023
neural precursor cell proliferationGO:00613511210.023
regulation of interferon beta biosynthetic processGO:004535740.023
fatty acid metabolic processGO:00066311210.023
phosphatidylinositol mediated signalingGO:0048015410.023
positive regulation of t cell costimulationGO:200052520.022
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.022
regulation of monocyte chemotaxisGO:009002530.022
signal transduction in absence of ligandGO:0038034550.022
microglial cell activationGO:000177430.022
regulation of peptidyl tyrosine phosphorylationGO:0050730930.022
calcium ion transportGO:00068161590.022
positive regulation of lymphocyte differentiationGO:0045621610.022
positive regulation of chemokine secretionGO:009019740.022
cell killingGO:0001906670.022
response to immune response of other organism involved in symbiotic interactionGO:005256430.022
organic acid biosynthetic processGO:0016053860.022
divalent inorganic cation homeostasisGO:00725071380.022
cytokine production involved in immune responseGO:0002367340.022
stress activated mapk cascadeGO:0051403800.022
regulation of platelet activationGO:0010543170.022
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.021
purine containing compound metabolic processGO:00725213110.021
cellular response to lipoteichoic acidGO:007122360.021
regulation of ossificationGO:00302781120.021
positive regulation of exocytosisGO:0045921200.021
regulation of synaptic growth at neuromuscular junctionGO:000858240.021
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.021
chemokine productionGO:0032602340.021
fatty acid derivative metabolic processGO:1901568330.021
negative regulation of cytokine productionGO:0001818840.021
eosinophil activationGO:004330710.021
positive regulation of leukocyte differentiationGO:1902107860.021
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.021
interferon alpha biosynthetic processGO:004534910.021
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007043010.021
positive regulation of mast cell activation involved in immune responseGO:0033008100.021
regulation of hormone levelsGO:00108172110.021
negative thymic t cell selectionGO:0045060120.021
negative regulation of t cell activationGO:0050868650.020
muscle cell differentiationGO:00426922610.020
regulation of intracellular protein transportGO:0033157820.020
regulation of membrane potentialGO:00423911920.020
regulation of myeloid leukocyte differentiationGO:0002761580.020
intracellular mrna localizationGO:000829840.020
regulation of cell cycle processGO:00105641600.020
leukocyte chemotaxisGO:0030595690.020
positive regulation of monocyte chemotaxisGO:009002620.020
calcium ion homeostasisGO:00550741270.020
negative regulation of homeostatic processGO:0032845710.020
purine ribonucleoside triphosphate catabolic processGO:00092071990.020
negative regulation of transferase activityGO:0051348850.020
positive regulation of interleukin 6 productionGO:0032755370.020
negative regulation of interferon gamma productionGO:0032689180.020
lateral inhibitionGO:004633110.020
regulation of antimicrobial peptide biosynthetic processGO:000280510.020
negative regulation of defense responseGO:0031348770.020
monocyte extravasationGO:003569620.020
multicellular organismal signalingGO:0035637910.020
positive regulation of monocyte extravasationGO:200043910.019
establishment of protein localization to organelleGO:00725941180.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.019

Lair1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.186
musculoskeletal system diseaseDOID:1700.186
connective tissue diseaseDOID:6500.186
disease of metabolismDOID:001466700.057
bone diseaseDOID:008000100.038
bone inflammation diseaseDOID:334200.033
arthritisDOID:84800.033
hypersensitivity reaction type ii diseaseDOID:41700.026
immune system diseaseDOID:291400.026
hypersensitivity reaction diseaseDOID:006005600.026
lupus erythematosusDOID:885700.026
acquired metabolic diseaseDOID:006015800.021
systemic lupus erythematosusDOID:907400.021
sensory system diseaseDOID:005015500.021
nervous system diseaseDOID:86300.021
rheumatoid arthritisDOID:714800.020