| protein modification by small protein conjugation | GO:0032446 | 187 | 0.385 | |
| protein ubiquitination | GO:0016567 | 171 | 0.224 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.223 | |
| protein neddylation | GO:0045116 | 1 | 0.192 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.104 | |
| protein catabolic process | GO:0030163 | 221 | 0.082 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.081 | |
| response to light stimulus | GO:0009416 | 135 | 0.077 | |
| multicellular organismal response to stress | GO:0033555 | 62 | 0.077 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.076 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.073 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.068 | |
| transmembrane transport | GO:0055085 | 412 | 0.065 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.065 | |
| sperm individualization | GO:0007291 | 1 | 0.062 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.061 | |
| dephosphorylation | GO:0016311 | 129 | 0.060 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.057 | |
| cellularization | GO:0007349 | 1 | 0.057 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.057 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.053 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.052 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.051 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.051 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.051 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.048 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.048 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.048 | |
| muscle tissue development | GO:0060537 | 308 | 0.047 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.047 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.046 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.045 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.044 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.043 | |
| spermatogenesis | GO:0007283 | 284 | 0.043 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.043 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.041 | |
| male gamete generation | GO:0048232 | 285 | 0.039 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.039 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.038 | |
| response to radiation | GO:0009314 | 165 | 0.037 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.037 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.036 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.036 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.035 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.033 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.033 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.033 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.033 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.033 | |
| spermatid differentiation | GO:0048515 | 115 | 0.033 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.032 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.031 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.031 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.031 | |
| regulation of cell division | GO:0051302 | 76 | 0.030 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.030 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.029 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.029 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.029 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.029 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.028 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.028 | |
| microtubule based process | GO:0007017 | 236 | 0.028 | |
| gtp metabolic process | GO:0046039 | 144 | 0.028 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.027 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.027 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.027 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 4 | 0.027 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.027 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.027 | |
| synaptonemal complex organization | GO:0070193 | 15 | 0.026 | |
| phosphatidylinositol metabolic process | GO:0046488 | 45 | 0.026 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.026 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.025 | |
| establishment of protein localization to golgi | GO:0072600 | 1 | 0.025 | |
| mapk cascade | GO:0000165 | 281 | 0.025 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.025 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.025 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.025 | |
| synaptic transmission | GO:0007268 | 329 | 0.024 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.024 | |
| cation transport | GO:0006812 | 399 | 0.024 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.023 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.023 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.023 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.023 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.023 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.023 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.022 | |
| glucose homeostasis | GO:0042593 | 128 | 0.022 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.022 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.022 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.021 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.021 | |
| exocytosis | GO:0006887 | 121 | 0.021 | |
| dna metabolic process | GO:0006259 | 303 | 0.021 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.021 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.021 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.020 | |
| regulation of glycogen catabolic process | GO:0005981 | 2 | 0.020 | |
| response to fibroblast growth factor | GO:0071774 | 47 | 0.020 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.020 | |
| jnk cascade | GO:0007254 | 72 | 0.020 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.020 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.020 | |
| muscle adaptation | GO:0043500 | 39 | 0.020 | |
| cilium movement | GO:0003341 | 28 | 0.020 | |
| cilium morphogenesis | GO:0060271 | 102 | 0.020 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.020 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.020 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 50 | 0.019 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.019 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.019 | |
| positive regulation of fibroblast growth factor receptor signaling pathway | GO:0045743 | 3 | 0.019 | |
| gtp catabolic process | GO:0006184 | 143 | 0.019 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.019 | |
| chiasma assembly | GO:0051026 | 6 | 0.019 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.019 | |
| cellular response to fibroblast growth factor stimulus | GO:0044344 | 47 | 0.018 | |
| chromatin modification | GO:0016568 | 187 | 0.018 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.018 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.018 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.018 | |
| neuron neuron synaptic transmission | GO:0007270 | 69 | 0.018 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.018 | |
| cellular homeostasis | GO:0019725 | 240 | 0.017 | |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.017 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.017 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.017 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.017 | |
| positive regulation of nfat protein import into nucleus | GO:0051533 | 1 | 0.017 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.017 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.017 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.016 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.016 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.016 | |
| germ cell development | GO:0007281 | 185 | 0.016 | |
| cytokinetic process | GO:0032506 | 2 | 0.016 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.016 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.016 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.016 | |
| axoneme assembly | GO:0035082 | 15 | 0.016 | |
| blood circulation | GO:0008015 | 195 | 0.016 | |
| regulation of response to dna damage stimulus | GO:2001020 | 34 | 0.016 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.016 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.016 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.016 | |
| regulation of transporter activity | GO:0032409 | 57 | 0.016 | |
| positive regulation of atpase activity | GO:0032781 | 3 | 0.015 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.015 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.015 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.015 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.015 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.015 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.015 | |
| protein localization to organelle | GO:0033365 | 185 | 0.015 | |
| response to growth factor | GO:0070848 | 198 | 0.015 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.015 | |
| sensory perception | GO:0007600 | 245 | 0.015 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.015 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.015 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.015 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.015 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.015 | |
| immune effector process | GO:0002252 | 321 | 0.015 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.015 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.014 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.014 | |
| protein maturation | GO:0051604 | 176 | 0.014 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.014 | |
| hormone secretion | GO:0046879 | 128 | 0.014 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.014 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.014 | |
| positive regulation of rac protein signal transduction | GO:0035022 | 1 | 0.014 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.014 | |
| learning or memory | GO:0007611 | 148 | 0.014 | |
| regulation of system process | GO:0044057 | 200 | 0.014 | |
| epithelial cilium movement | GO:0003351 | 12 | 0.014 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.014 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.014 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.014 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.014 | |
| spermatid development | GO:0007286 | 108 | 0.014 | |
| dna recombination | GO:0006310 | 92 | 0.014 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.013 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.013 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.013 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.013 | |
| heart process | GO:0003015 | 94 | 0.013 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.013 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.013 | |
| muscle system process | GO:0003012 | 141 | 0.013 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.013 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.013 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.013 | |
| membrane organization | GO:0061024 | 245 | 0.013 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.013 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 159 | 0.013 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.013 | |
| multicellular organism growth | GO:0035264 | 161 | 0.013 | |
| negative regulation of cell motility | GO:2000146 | 61 | 0.013 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.013 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.013 | |
| regulation of glutamate receptor signaling pathway | GO:1900449 | 16 | 0.013 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.013 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.013 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.013 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.013 | |
| t cell proliferation | GO:0042098 | 120 | 0.013 | |
| muscle cell development | GO:0055001 | 133 | 0.013 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.013 | |
| histone h2a ubiquitination | GO:0033522 | 3 | 0.013 | |
| organelle localization | GO:0051640 | 179 | 0.012 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.012 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.012 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.012 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.012 | |
| mitochondrion transport along microtubule | GO:0047497 | 3 | 0.012 | |
| peptide transport | GO:0015833 | 133 | 0.012 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.012 | |
| regulation of cytokinesis | GO:0032465 | 5 | 0.012 | |
| amide transport | GO:0042886 | 138 | 0.012 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.012 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.012 | |
| thermosensory behavior | GO:0040040 | 1 | 0.012 | |
| positive regulation of atp catabolic process | GO:1903291 | 3 | 0.012 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.012 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.012 | |
| lipid localization | GO:0010876 | 126 | 0.012 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.012 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.012 | |
| positive regulation of cell cycle process | GO:0090068 | 61 | 0.012 | |
| cognition | GO:0050890 | 149 | 0.012 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.012 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.012 | |
| response to monosaccharide | GO:0034284 | 67 | 0.012 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.012 | |
| dipeptide transport | GO:0042938 | 2 | 0.012 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.012 | |
| protein processing | GO:0016485 | 163 | 0.012 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.012 | |
| response to oxygen levels | GO:0070482 | 62 | 0.012 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.011 | |
| hematopoietic stem cell migration | GO:0035701 | 1 | 0.011 | |
| cellular polysaccharide metabolic process | GO:0044264 | 38 | 0.011 | |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.011 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.011 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.011 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.011 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.011 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.011 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.011 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.011 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.011 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.011 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.011 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.011 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.011 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.011 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.011 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.011 | |
| oxidation reduction process | GO:0055114 | 342 | 0.011 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.011 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.011 | |
| regulation of g1 s transition of mitotic cell cycle | GO:2000045 | 35 | 0.010 | |
| organelle assembly | GO:0070925 | 177 | 0.010 | |
| protein localization to chromatin | GO:0071168 | 3 | 0.010 | |
| meiosis i | GO:0007127 | 60 | 0.010 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.010 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.010 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.010 | |
| protein localization to chromosome centromeric region | GO:0071459 | 1 | 0.010 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.010 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.010 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 2 | 0.010 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.010 | |
| t cell activation | GO:0042110 | 289 | 0.010 | |
