Mus musculus

0 known processes

Trex2

three prime repair exonuclease 2

(Aliases: MGC129477,MGC129476)

Trex2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transferase activityGO:00513382630.249
organonitrogen compound catabolic processGO:19015652640.175
purine nucleoside metabolic processGO:00422782410.145
cellular ketone metabolic processGO:0042180840.142
small gtpase mediated signal transductionGO:0007264970.135
ras protein signal transductionGO:0007265770.125
regulation of kinase activityGO:00435492490.121
inflammatory responseGO:00069542440.116
positive regulation of lymphocyte activationGO:00512511400.115
regulation of hydrolase activityGO:00513362460.106
regulation of ion transportGO:00432692150.101
nucleoside catabolic processGO:00091642060.100
regulation of cell activationGO:00508652890.096
cellular amine metabolic processGO:0044106440.093
cation transportGO:00068123990.092
positive regulation of cellular amino acid metabolic processGO:004576430.090
purine ribonucleoside catabolic processGO:00461302050.086
regulation of cellular ketone metabolic processGO:0010565660.085
regulation of protein transportGO:00512231630.083
purine nucleotide metabolic processGO:00061633020.083
purine containing compound metabolic processGO:00725213110.083
leukocyte proliferationGO:00706611720.083
purine nucleoside catabolic processGO:00061522050.083
purine ribonucleoside metabolic processGO:00461282410.082
purine containing compound catabolic processGO:00725232130.081
cellular amino acid metabolic processGO:00065201030.080
regulation of lymphocyte activationGO:00512492400.077
regulation of nucleoside metabolic processGO:00091181300.076
positive regulation of hydrolase activityGO:00513451480.074
regulation of defense responseGO:00313472330.074
purine ribonucleoside triphosphate catabolic processGO:00092071990.073
cellular calcium ion homeostasisGO:00068741190.073
aromatic compound catabolic processGO:00194392860.069
Mouse
nucleoside phosphate metabolic processGO:00067533380.068
purine ribonucleotide metabolic processGO:00091502900.067
ribose phosphate metabolic processGO:00196932910.066
positive regulation of protein modification processGO:00314012990.066
negative regulation of protein metabolic processGO:00512482820.063
regulation of protein kinase activityGO:00458592320.063
organic cyclic compound catabolic processGO:19013612950.062
Mouse
heterocycle catabolic processGO:00467002800.061
Mouse
nucleoside triphosphate catabolic processGO:00091432050.061
rho protein signal transductionGO:0007266320.060
metal ion homeostasisGO:00550651890.060
negative regulation of molecular functionGO:00440922580.057
regulation of cellular catabolic processGO:00313292420.057
ribonucleoside metabolic processGO:00091192450.057
glycosyl compound catabolic processGO:19016582060.056
nitrogen compound transportGO:00717052710.055
cytokine productionGO:00018163190.054
ion transmembrane transportGO:00342203610.054
transmission of nerve impulseGO:0019226760.054
positive regulation of defense responseGO:00313491240.054
synaptic transmissionGO:00072683290.053
amine metabolic processGO:0009308450.052
inorganic ion transmembrane transportGO:00986602340.051
positive regulation of t cell differentiationGO:0045582520.050
cellular nitrogen compound catabolic processGO:00442702800.050
Mouse
negative regulation of phosphate metabolic processGO:00459361840.050
carbohydrate derivative catabolic processGO:19011362310.050
macromolecule catabolic processGO:00090572810.050
Mouse
gtp metabolic processGO:00460391440.049
regulation of membrane potentialGO:00423911920.048
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.047
organophosphate catabolic processGO:00464342320.047
positive regulation of response to woundingGO:1903036660.047
positive regulation of leukocyte differentiationGO:1902107860.047
leukocyte differentiationGO:00025213420.046
nucleotide metabolic processGO:00091173320.046
regulation of map kinase activityGO:00434051200.046
skin developmentGO:00435882200.045
regulation of metal ion transportGO:00109591060.045
cytosolic calcium ion homeostasisGO:0051480700.044
regulation of cellular amino acid metabolic processGO:000652150.043
purine ribonucleotide catabolic processGO:00091542080.043
purine ribonucleoside triphosphate metabolic processGO:00092052200.043
nucleobase containing small molecule metabolic processGO:00550863520.043
purine nucleotide catabolic processGO:00061952110.043
positive regulation of cellular catabolic processGO:00313311480.043
nucleoside triphosphate metabolic processGO:00091412300.042
cellular homeostasisGO:00197252400.041
wound healingGO:00420601570.041
negative regulation of phosphorus metabolic processGO:00105631840.040
transmembrane transportGO:00550854120.040
positive regulation of inflammatory responseGO:0050729470.040
gtp catabolic processGO:00061841430.040
t cell activationGO:00421102890.039
cellular chemical homeostasisGO:00550822150.039
glycosyl compound metabolic processGO:19016572460.039
regulation of nucleotide catabolic processGO:00308111220.039
regulation of t cell activationGO:00508631700.039
purine nucleoside triphosphate catabolic processGO:00091462030.039
striated muscle contractionGO:0006941450.038
regulation of purine nucleotide catabolic processGO:00331211220.038
positive regulation of protein phosphorylationGO:00019342420.038
purine nucleoside triphosphate metabolic processGO:00091442260.038
regulation of leukocyte differentiationGO:19021051590.038
positive regulation of nucleotide metabolic processGO:00459811140.037
regulation of purine nucleotide metabolic processGO:19005421690.037
guanosine containing compound catabolic processGO:19010691440.036
ribonucleotide catabolic processGO:00092612080.036
sequestering of calcium ionGO:0051208180.036
regulation of peptidase activityGO:0052547960.036
peptidyl amino acid modificationGO:00181933360.036
phospholipid metabolic processGO:0006644870.035
regulation of cellular amine metabolic processGO:0033238200.035
negative regulation of cellular protein metabolic processGO:00322692470.035
mapk cascadeGO:00001652810.035
inorganic cation transmembrane transportGO:00986622070.035
negative regulation of transferase activityGO:0051348850.035
anion transportGO:00068201770.035
action potentialGO:0001508780.034
lipid localizationGO:00108761260.034
response to organonitrogen compoundGO:00102432460.034
negative regulation of kinase activityGO:0033673810.034
ribonucleoside triphosphate catabolic processGO:00092031990.033
vesicle localizationGO:0051648860.033
ribonucleoside catabolic processGO:00424542060.032
organic hydroxy compound transportGO:0015850930.032
ribonucleotide metabolic processGO:00092592910.032
maintenance of locationGO:0051235890.031
multicellular organismal signalingGO:0035637910.031
regulation of lymphocyte differentiationGO:00456191070.031
calcium ion homeostasisGO:00550741270.031
regulation of ras protein signal transductionGO:00465781140.031
regulation of cytokine productionGO:00018172660.030
g protein coupled receptor signaling pathwayGO:00071862430.030
hair follicle developmentGO:0001942850.029
positive regulation of cellular amine metabolic processGO:003324050.029
regulation of proteolysisGO:00301621640.029
hormone metabolic processGO:0042445860.029
cation homeostasisGO:00550802120.029
regulation of leukocyte proliferationGO:00706631210.029
positive regulation of mapk cascadeGO:00434101700.028
regulation of rho gtpase activityGO:0032319580.028
carbohydrate metabolic processGO:00059752300.028
peptidyl tyrosine modificationGO:00182121450.028
spermatogenesisGO:00072832840.028
lymphocyte proliferationGO:00466511640.028
nucleoside phosphate catabolic processGO:19012922220.028
membrane organizationGO:00610242450.026
heart morphogenesisGO:00030071780.026
learning or memoryGO:00076111480.026
positive regulation of cell activationGO:00508671580.026
guanosine containing compound metabolic processGO:19010681440.026
actin cytoskeleton organizationGO:00300362200.026
sequestering of metal ionGO:0051238190.026
calcium ion transportGO:00068161590.026
regulation of protein serine threonine kinase activityGO:00719001570.026
positive regulation of cytokine productionGO:00018191740.025
multicellular organismal homeostasisGO:00488711640.025
regulation of ras gtpase activityGO:0032318880.025
cytokine secretionGO:0050663720.025
negative regulation of phosphorylationGO:00423261660.025
protein catabolic processGO:00301632210.025
cell adhesionGO:00071553290.025
regulation of lipid metabolic processGO:00192161180.025
regulation of epithelial cell proliferationGO:00506781410.025
cellular modified amino acid metabolic processGO:0006575630.025
positive regulation of b cell chemotaxisGO:200053820.025
positive regulation of t cell activationGO:00508701010.025
calcium ion transport into cytosolGO:0060402480.025
positive regulation of protein transportGO:0051222930.024
epidermis developmentGO:00085441870.024
regulation of secretionGO:00510462740.024
negative regulation of inflammatory responseGO:0050728610.024
sodium ion transportGO:0006814730.024
organic hydroxy compound metabolic processGO:19016152030.024
regulation of t cell differentiationGO:0045580830.024
monocarboxylic acid metabolic processGO:00327871910.024
regulation of protein localizationGO:00328802310.024
regulation of mapk cascadeGO:00434082480.023
regulation of inflammatory responseGO:00507271470.023
positive regulation of nucleotide catabolic processGO:0030813880.023
regulation of cell motilityGO:20001452360.023
ensheathment of neuronsGO:0007272760.023
exocytosisGO:00068871210.023
cellular divalent inorganic cation homeostasisGO:00725031270.023
regulation of hormone levelsGO:00108172110.023
nucleotide catabolic processGO:00091662170.023
regulation of rho protein signal transductionGO:0035023710.023
protein localization to membraneGO:00726571080.023
neuronal action potentialGO:0019228540.022
positive regulation of purine nucleotide metabolic processGO:19005441140.022
regulation of gtp catabolic processGO:00331241130.022
regulation of homeostatic processGO:00328441820.022
cellular ion homeostasisGO:00068731650.022
regulation of anatomical structure sizeGO:00900661780.022
positive regulation of map kinase activityGO:0043406840.021
cellular response to growth factor stimulusGO:00713631970.021
positive regulation of lymphocyte differentiationGO:0045621610.021
cellular metal ion homeostasisGO:00068751510.021
divalent inorganic cation homeostasisGO:00725071380.021
blood circulationGO:00080151950.021
positive regulation of ion transportGO:0043270650.021
regulation of protein catabolic processGO:00421761080.021
sterol homeostasisGO:0055092450.021
lipid homeostasisGO:0055088630.021
innate immune responseGO:00450871570.021
regulation of response to woundingGO:19030341890.020
positive regulation of purine nucleotide catabolic processGO:0033123880.020
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.020
myeloid leukocyte differentiationGO:00025731190.020
tissue homeostasisGO:00018941150.020
hydrogen ion transmembrane transportGO:1902600250.020
lymphocyte differentiationGO:00300982420.020
cytokine mediated signaling pathwayGO:00192211150.020
negative regulation of intracellular signal transductionGO:19025321670.020
alpha beta t cell differentiationGO:0046632690.020
t cell proliferationGO:00420981200.020
leukocyte migrationGO:00509001240.020
gland developmentGO:00487323300.020
immune response activating signal transductionGO:00027571160.020
regulation of establishment of protein localizationGO:00702011810.020
male gamete generationGO:00482322850.020
cell chemotaxisGO:0060326810.020
nucleoside metabolic processGO:00091162460.019
ribonucleoside triphosphate metabolic processGO:00091992200.019
negative regulation of cellular component organizationGO:00511291940.019
peptidyl serine modificationGO:0018209830.019
response to radiationGO:00093141650.019
positive regulation of secretionGO:00510471300.019
epithelial cell proliferationGO:00506731740.019
regulation of interleukin 6 productionGO:0032675550.019
peptidyl tyrosine phosphorylationGO:00181081430.018
divalent inorganic cation transportGO:00725111780.018
positive regulation of gtpase activityGO:0043547850.018
regulation of nucleotide metabolic processGO:00061401690.018
cellular lipid metabolic processGO:00442553230.018
cell activation involved in immune responseGO:00022631260.018
monosaccharide metabolic processGO:00059961060.018
organic acid transportGO:00158491010.018
alcohol metabolic processGO:00060661160.018
positive regulation of protein kinase activityGO:00458601440.018
somatotropin secreting cell differentiationGO:006012640.017
regulation of lymphocyte proliferationGO:00506701170.017
regulation of system processGO:00440572000.017
extrinsic apoptotic signaling pathwayGO:00971911260.017
axon ensheathmentGO:0008366760.017
positive regulation of ras gtpase activityGO:0032320650.017
carboxylic acid biosynthetic processGO:0046394860.017
eosinophil migrationGO:007267730.017
regulation of calcium ion transportGO:0051924690.017
regulation of stress activated mapk cascadeGO:0032872690.017
regulation of jnk cascadeGO:0046328620.017
negative regulation of cytokine productionGO:0001818840.017
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathwayGO:001057930.017
spermatid differentiationGO:00485151150.017
response to growth factorGO:00708481980.016
multi multicellular organism processGO:00447061090.016
response to extracellular stimulusGO:00099911270.016
organonitrogen compound biosynthetic processGO:19015661920.016
urogenital system developmentGO:00016552610.016
leukocyte activation involved in immune responseGO:00023661260.016
bone remodelingGO:0046849530.016
cytoplasmic transportGO:00164822340.016
positive regulation of kinase activityGO:00336741550.016
response to steroid hormoneGO:0048545560.016
response to light stimulusGO:00094161350.016
positive regulation of vasoconstrictionGO:004590740.016
hexose transmembrane transportGO:003542870.016
negative regulation of epithelial cell proliferationGO:0050680640.015
synaptic vesicle transportGO:0048489570.015
endocytosisGO:00068971680.015
regulation of endopeptidase activityGO:0052548890.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
negative regulation of protein phosphorylationGO:00019331260.015
organelle localizationGO:00516401790.015
positive regulation of cell motilityGO:20001471160.015
positive regulation of eosinophil migrationGO:200041820.015
engulfment of apoptotic cellGO:004365230.015
lymphocyte apoptotic processGO:0070227540.015
ceramide biosynthetic processGO:0046513200.014
thymocyte migrationGO:007267920.014
regulation of cytokine secretionGO:0050707610.014
striated muscle tissue developmentGO:00147062930.014
monocarboxylic acid transportGO:0015718440.014
protein processingGO:00164851630.014
regulation of sodium ion transportGO:0002028290.014
regulation of cell adhesionGO:00301551540.014
positive regulation of interleukin 8 productionGO:003275720.014
lipid transportGO:0006869980.014
sensory perception of mechanical stimulusGO:00509541070.014
exocrine system developmentGO:0035272450.014
carboxylic acid catabolic processGO:0046395510.014
morphogenesis of a branching structureGO:00017632030.014
regulation of cell shapeGO:0008360390.014
regulation of cellular component sizeGO:00325351210.014
positive regulation of stress activated mapk cascadeGO:0032874480.014
glycoprotein metabolic processGO:00091001160.014
regulation of intracellular transportGO:00323861590.014
cation transmembrane transportGO:00986552660.014
positive regulation of cytokine secretionGO:0050715410.014
sulfur compound metabolic processGO:00067901000.014
response to nutrient levelsGO:00316671090.014
regulation of cell migrationGO:00303342190.014
regulation of cell morphogenesis involved in differentiationGO:00107691510.013
regulation of secretion by cellGO:19035302490.013
neurotransmitter transportGO:0006836760.013
response to ethanolGO:0045471180.013
positive regulation of programmed cell deathGO:00430682180.013
plasma membrane repairGO:000177870.013
regulation of lymphocyte apoptotic processGO:0070228410.013
ossificationGO:00015032160.013
germ cell developmentGO:00072811850.013
positive regulation of thymocyte migrationGO:200041220.013
purine containing compound transmembrane transportGO:007253020.013
hormone secretionGO:00468791280.013
leukocyte chemotaxisGO:0030595690.013
osteoclast differentiationGO:0030316620.013
cellular response to extracellular stimulusGO:0031668810.013
positive regulation of transferase activityGO:00513471670.013
phenol containing compound metabolic processGO:0018958600.013
positive regulation of proteolysisGO:0045862850.013
posttranscriptional regulation of gene expressionGO:00106081550.013
monocarboxylic acid catabolic processGO:0072329270.013
cholesterol homeostasisGO:0042632440.013
jnk cascadeGO:0007254720.013
chondroitin sulfate metabolic processGO:0030204170.012
microtubule based processGO:00070172360.012
carboxylic acid transportGO:00469421000.012
negative regulation of defense responseGO:0031348770.012
cell cycle switchingGO:006018410.012
muscle system processGO:00030121410.012
epithelial cell migrationGO:0010631630.012
positive regulation of phospholipase activityGO:001051830.012
positive regulation of natural killer cell chemotaxisGO:200050310.012
oxidation reduction processGO:00551143420.012
lactationGO:0007595250.012
tissue regenerationGO:0042246220.012
positive regulation of interleukin 6 productionGO:0032755370.012
extracellular matrix organizationGO:00301981470.012
regulation of leukocyte apoptotic processGO:2000106560.012
regulation of transforming growth factor beta2 productionGO:003290920.012
regulation of cytoplasmic transportGO:19036491120.012
sensory perceptionGO:00076002450.012
positive regulation of protein serine threonine kinase activityGO:00719021060.012
mitotic cell cycleGO:00002781950.012
positive regulation of nucleoside metabolic processGO:0045979910.012
positive regulation of cytosolic calcium ion concentrationGO:0007204650.012
cytosolic calcium ion transportGO:0060401480.012
short chain fatty acid catabolic processGO:001962620.012
defense response to bacteriumGO:00427421190.012
acute inflammatory responseGO:0002526410.011
muscle cell differentiationGO:00426922610.011
biomineral tissue developmentGO:0031214640.011
negative regulation of protein modification processGO:00314001630.011
embryonic placenta developmentGO:0001892980.011
regulation of neuron differentiationGO:00456642810.011
neuron migrationGO:00017641220.011
anatomical structure homeostasisGO:00602491450.011
cell type specific apoptotic processGO:00972852680.011
negative regulation of camp mediated signalingGO:004395130.011
glycosylationGO:0070085620.011
response to molecule of bacterial originGO:00022371430.011
alpha beta t cell activationGO:0046631910.011
positive regulation of cell migrationGO:00303351090.011
negative regulation of leukocyte differentiationGO:1902106510.011
adult behaviorGO:00305341350.011
regulation of cellular response to stressGO:00801351590.011
response to organic cyclic compoundGO:00140701980.011
regulation of ion homeostasisGO:2000021640.011
stress activated mapk cascadeGO:0051403800.011
negative regulation of mapk cascadeGO:0043409650.011
protein secretionGO:00093061110.011
extraocular skeletal muscle developmentGO:000207420.011
hematopoietic progenitor cell differentiationGO:00022441430.011
circulatory system processGO:00030131970.011
regulation of wnt signaling pathwayGO:00301111230.011
molting cycleGO:0042303900.011
sphingolipid metabolic processGO:0006665450.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
wnt signaling pathwayGO:00160551880.011
response to starvationGO:0042594650.011
endothelial cell migrationGO:0043542440.011
stress activated protein kinase signaling cascadeGO:0031098810.011
positive regulation of membrane protein ectodomain proteolysisGO:005104430.011
regulation of ion transmembrane transportGO:00347651190.011
modification dependent macromolecule catabolic processGO:00436321330.011
regulation of b cell activationGO:0050864810.011
developmental maturationGO:00217001930.011
activation of mapk activityGO:0000187590.011
establishment of vesicle localizationGO:0051650810.011
cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:003952840.010
immune effector processGO:00022523210.010
response to acid chemicalGO:00011011110.010
regulation of translationGO:0006417710.010
positive regulation of rho gtpase activityGO:0032321410.010
interleukin 6 productionGO:0032635580.010
energy coupled proton transmembrane transport against electrochemical gradientGO:001598830.010
chemotaxisGO:00069352470.010
response to peptideGO:19016521360.010
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.010
compound eye developmentGO:004874910.010
establishment of organelle localizationGO:00516561220.010
positive regulation of intracellular transportGO:0032388700.010

Trex2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011