Mus musculus

39 known processes

Trex1

three prime repair exonuclease 1

(Aliases: AU041952,1661)

Trex1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amino acid metabolic processGO:000652150.072
cellular amino acid metabolic processGO:00065201030.071
positive regulation of cellular amino acid metabolic processGO:004576430.066
cytokine productionGO:00018163190.063
regulation of cellular ketone metabolic processGO:0010565660.060
amine metabolic processGO:0009308450.057
cellular amine metabolic processGO:0044106440.053
regulation of cellular amine metabolic processGO:0033238200.053
positive regulation of cellular amine metabolic processGO:003324050.052
regulation of defense responseGO:00313472330.052
regulation of cytokine productionGO:00018172660.050
immune effector processGO:00022523210.047
cellular ketone metabolic processGO:0042180840.046
cation transportGO:00068123990.043
positive regulation of protein modification processGO:00314012990.037
peptidyl amino acid modificationGO:00181933360.037
t cell activationGO:00421102890.036
negative regulation of immune system processGO:00026832090.035
myeloid cell differentiationGO:00300992330.034
innate immune responseGO:00450871570.031
protein modification by small protein conjugation or removalGO:00706472070.031
regulation of cell activationGO:00508652890.031
leukocyte differentiationGO:00025213420.031
ribonucleotide metabolic processGO:00092592910.030
defense response to other organismGO:00985421970.030
mapk cascadeGO:00001652810.030
positive regulation of cytokine productionGO:00018191740.030
activation of immune responseGO:00022531380.029
cellular response to lipopolysaccharideGO:0071222770.028
oxidation reduction processGO:00551143420.028
nucleotide metabolic processGO:00091173320.028
spermatogenesisGO:00072832840.027
cell adhesionGO:00071553290.027
nucleoside phosphate metabolic processGO:00067533380.027
ras protein signal transductionGO:0007265770.026
multicellular organismal homeostasisGO:00488711640.026
lymphocyte differentiationGO:00300982420.026
response to molecule of bacterial originGO:00022371430.026
cellular response to lipidGO:00713961450.026
regulation of lymphocyte activationGO:00512492400.026
male gamete generationGO:00482322850.026
heterocycle catabolic processGO:00467002800.026
response to organonitrogen compoundGO:00102432460.025
macromolecule catabolic processGO:00090572810.025
positive regulation of defense responseGO:00313491240.025
purine nucleotide metabolic processGO:00061633020.025
immune response regulating signaling pathwayGO:00027641250.025
cellular response to biotic stimulusGO:0071216920.025
reactive oxygen species metabolic processGO:0072593840.025
purine ribonucleotide metabolic processGO:00091502900.025
regulation of cell motilityGO:20001452360.024
apoptotic signaling pathwayGO:00971903060.024
nucleobase containing small molecule metabolic processGO:00550863520.024
protein modification by small protein conjugationGO:00324461870.024
regulation of cellular catabolic processGO:00313292420.024
protein ubiquitinationGO:00165671710.024
regulation of mapk cascadeGO:00434082480.024
regulation of neuron differentiationGO:00456642810.024
nitrogen compound transportGO:00717052710.023
regulation of secretionGO:00510462740.023
response to lipopolysaccharideGO:00324961280.023
negative regulation of molecular functionGO:00440922580.023
small gtpase mediated signal transductionGO:0007264970.023
regulation of protein localizationGO:00328802310.023
negative regulation of cell proliferationGO:00082852960.023
hematopoietic progenitor cell differentiationGO:00022441430.023
regulation of organelle organizationGO:00330432890.023
aromatic compound catabolic processGO:00194392860.023
negative regulation of cellular component organizationGO:00511291940.023
purine containing compound metabolic processGO:00725213110.023
positive regulation of protein phosphorylationGO:00019342420.023
cation homeostasisGO:00550802120.023
ion transmembrane transportGO:00342203610.022
carbohydrate metabolic processGO:00059752300.022
leukocyte mediated immunityGO:00024431740.022
muscle tissue developmentGO:00605373080.022
inflammatory responseGO:00069542440.022
carbohydrate derivative biosynthetic processGO:19011371830.022
immune response activating signal transductionGO:00027571160.022
cellular homeostasisGO:00197252400.022
gland developmentGO:00487323300.022
negative regulation of cellular amine metabolic processGO:003323910.022
cation transmembrane transportGO:00986552660.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.022
carbohydrate derivative catabolic processGO:19011362310.021
regulation of cellular component biogenesisGO:00440871810.021
negative regulation of protein metabolic processGO:00512482820.021
cellular macromolecule catabolic processGO:00442652060.021
regulation of establishment of protein localizationGO:00702011810.021
cellular response to cytokine stimulusGO:00713451890.021
negative regulation of cellular protein metabolic processGO:00322692470.021
cell activation involved in immune responseGO:00022631260.021
organic cyclic compound catabolic processGO:19013612950.021
cell type specific apoptotic processGO:00972852680.021
regulation of hormone levelsGO:00108172110.021
regulation of secretion by cellGO:19035302490.021
rho protein signal transductionGO:0007266320.021
leukocyte proliferationGO:00706611720.021
response to acid chemicalGO:00011011110.021
adaptive immune responseGO:00022501550.020
leukocyte activation involved in immune responseGO:00023661260.020
cellular response to molecule of bacterial originGO:0071219830.020
cellular nitrogen compound catabolic processGO:00442702800.020
positive regulation of innate immune responseGO:0045089800.020
homeostasis of number of cellsGO:00488722100.020
ossificationGO:00015032160.020
lymphocyte proliferationGO:00466511640.020
purine nucleoside metabolic processGO:00422782410.020
cellular response to organonitrogen compoundGO:00714171450.020
protein maturationGO:00516041760.020
transmembrane transportGO:00550854120.020
ribose phosphate metabolic processGO:00196932910.020
posttranscriptional regulation of gene expressionGO:00106081550.020
lymphocyte mediated immunityGO:00024491390.019
cellular chemical homeostasisGO:00550822150.019
metal ion homeostasisGO:00550651890.019
myeloid leukocyte differentiationGO:00025731190.019
g protein coupled receptor signaling pathwayGO:00071862430.019
protein catabolic processGO:00301632210.019
organonitrogen compound catabolic processGO:19015652640.019
dna metabolic processGO:00062593030.019
positive regulation of cell developmentGO:00107202370.019
blood vessel morphogenesisGO:00485142850.019
nucleoside metabolic processGO:00091162460.019
regulation of leukocyte differentiationGO:19021051590.019
regulation of t cell activationGO:00508631700.019
organophosphate catabolic processGO:00464342320.019
endocytosisGO:00068971680.019
muscle cell differentiationGO:00426922610.019
striated muscle tissue developmentGO:00147062930.019
glycosyl compound metabolic processGO:19016572460.019
purine ribonucleoside metabolic processGO:00461282410.019
regulation of intracellular transportGO:00323861590.019
cytoplasmic transportGO:00164822340.019
positive regulation of nervous system developmentGO:00519622210.019
negative regulation of cellular amino acid metabolic processGO:004576300.019
regulation of kinase activityGO:00435492490.019
glycoprotein metabolic processGO:00091001160.018
action potentialGO:0001508780.018
regulation of hydrolase activityGO:00513362460.018
regulation of reactive oxygen species metabolic processGO:2000377400.018
angiogenesisGO:00015252010.018
fat cell differentiationGO:00454441600.018
nucleoside catabolic processGO:00091642060.018
ribonucleoside metabolic processGO:00091192450.018
purine containing compound catabolic processGO:00725232130.018
synaptic transmissionGO:00072683290.018
regulation of innate immune responseGO:0045088910.018
response to organic cyclic compoundGO:00140701980.018
regulation of protein transportGO:00512231630.018
positive regulation of apoptotic processGO:00430652170.018
regulation of cell projection organizationGO:00313442060.018
positive regulation of cell activationGO:00508671580.018
regulation of leukocyte proliferationGO:00706631210.018
skeletal system developmentGO:00015013560.017
lateral inhibitionGO:004633110.017
cellular response to dna damage stimulusGO:00069742070.017
purine ribonucleoside triphosphate metabolic processGO:00092052200.017
regulation of leukocyte mediated immunityGO:00027031040.017
regulation of apoptotic signaling pathwayGO:20012331970.017
leukocyte migrationGO:00509001240.017
divalent inorganic cation transportGO:00725111780.017
inorganic cation transmembrane transportGO:00986622070.017
regulation of epithelial cell proliferationGO:00506781410.017
anion transportGO:00068201770.017
purine ribonucleotide catabolic processGO:00091542080.017
b cell activationGO:00421131610.017
negative regulation of phosphorus metabolic processGO:00105631840.017
regulation of membrane potentialGO:00423911920.017
cellular response to acid chemicalGO:0071229680.017
negative regulation of phosphate metabolic processGO:00459361840.017
reactive nitrogen species metabolic processGO:200105700.017
intracellular protein transportGO:00068862040.017
regulation of transferase activityGO:00513382630.017
defense response to bacteriumGO:00427421190.017
regulation of cell migrationGO:00303342190.016
compound eye developmentGO:004874910.016
inorganic ion transmembrane transportGO:00986602340.016
positive regulation of programmed cell deathGO:00430682180.016
maintenance of locationGO:0051235890.016
organelle fissionGO:00482851700.016
regulation of lymphocyte proliferationGO:00506701170.016
organonitrogen compound biosynthetic processGO:19015661920.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
lipid biosynthetic processGO:00086101790.016
cell substrate adhesionGO:00315891300.016
forebrain developmentGO:00309003020.016
microtubule based processGO:00070172360.016
positive regulation of immune effector processGO:00026991070.016
cellular lipid metabolic processGO:00442553230.016
epithelial cell proliferationGO:00506731740.016
cellular metal ion homeostasisGO:00068751510.016
actin cytoskeleton organizationGO:00300362200.016
regulation of proteolysisGO:00301621640.016
sequestering of metal ionGO:0051238190.016
ribonucleoside catabolic processGO:00424542060.016
regulation of ion transportGO:00432692150.016
negative regulation of cell activationGO:00508661110.016
negative regulation of intracellular signal transductionGO:19025321670.016
nucleoside phosphate catabolic processGO:19012922220.016
sensory perceptionGO:00076002450.016
purine ribonucleoside catabolic processGO:00461302050.016
regulation of homeostatic processGO:00328441820.016
regulation of response to woundingGO:19030341890.015
skeletal muscle organ developmentGO:00605381630.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
purine nucleotide catabolic processGO:00061952110.015
protein processingGO:00164851630.015
positive regulation of lymphocyte activationGO:00512511400.015
regulation of neuron projection developmentGO:00109751690.015
response to growth factorGO:00708481980.015
regulation of cell cycleGO:00517262810.015
t cell differentiationGO:00302171740.015
regulation of interleukin 10 secretionGO:200117940.015
membrane organizationGO:00610242450.015
blood circulationGO:00080151950.015
glucose homeostasisGO:00425931280.015
calcium ion transportGO:00068161590.015
positive regulation of hydrolase activityGO:00513451480.015
chemotaxisGO:00069352470.015
modification dependent protein catabolic processGO:00199411330.015
nucleocytoplasmic transportGO:00069131390.015
anatomical structure homeostasisGO:00602491450.015
regulation of system processGO:00440572000.015
positive regulation of mapk cascadeGO:00434101700.015
lymphocyte activation involved in immune responseGO:0002285930.015
proteolysis involved in cellular protein catabolic processGO:00516031470.015
endomembrane system organizationGO:00102561470.015
cellular ion homeostasisGO:00068731650.015
cellular response to hormone stimulusGO:00328701500.015
negative regulation of defense responseGO:0031348770.015
positive regulation of secretionGO:00510471300.015
organelle localizationGO:00516401790.015
regulation of feeding behaviorGO:006025930.015
cytokine mediated signaling pathwayGO:00192211150.014
purine nucleoside catabolic processGO:00061522050.014
sequestering of calcium ionGO:0051208180.014
wnt signaling pathwayGO:00160551880.014
embryonic organ morphogenesisGO:00485622760.014
nuclear transportGO:00511691390.014
defense response to virusGO:0051607680.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
connective tissue developmentGO:00614481790.014
regulation of anatomical structure sizeGO:00900661780.014
dephosphorylationGO:00163111290.014
nucleoside triphosphate catabolic processGO:00091432050.014
regulation of vesicle mediated transportGO:00606271390.014
regulation of inflammatory responseGO:00507271470.014
nucleoside triphosphate metabolic processGO:00091412300.014
production of molecular mediator of immune responseGO:00024401030.014
regulation of protein kinase activityGO:00458592320.014
ribonucleotide catabolic processGO:00092612080.014
stem cell differentiationGO:00488632680.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
reactive oxygen species biosynthetic processGO:190340980.014
t cell proliferationGO:00420981200.014
interleukin 10 secretionGO:007260840.014
organic hydroxy compound metabolic processGO:19016152030.014
positive regulation of kinase activityGO:00336741550.014
positive regulation of secretion by cellGO:19035321140.014
positive regulation of transferase activityGO:00513471670.014
mitotic cell cycleGO:00002781950.014
respiratory system developmentGO:00605411900.014
rhythmic processGO:00485111740.014
ribonucleoside triphosphate catabolic processGO:00092031990.014
positive regulation of cell deathGO:00109422240.014
myosin filament organizationGO:003103330.014
response to peptideGO:19016521360.014
camera type eye developmentGO:00430102660.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of cytoplasmic transportGO:19036491120.014
chromatin organizationGO:00063252060.013
monocarboxylic acid metabolic processGO:00327871910.013
divalent metal ion transportGO:00708381720.013
cellular protein complex assemblyGO:00436231160.013
peptidyl tyrosine modificationGO:00182121450.013
negative regulation of protein modification processGO:00314001630.013
regulation of purine nucleotide metabolic processGO:19005421690.013
immune response regulating cell surface receptor signaling pathwayGO:0002768800.013
positive regulation of nucleotide metabolic processGO:00459811140.013
immune response activating cell surface receptor signaling pathwayGO:0002429720.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
neuron deathGO:00709971540.013
sulfur compound metabolic processGO:00067901000.013
epithelial cell developmentGO:00020641590.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
positive regulation of cellular catabolic processGO:00313311480.013
ubiquitin dependent protein catabolic processGO:00065111290.013
glycosyl compound catabolic processGO:19016582060.013
histone modificationGO:00165701590.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
multicellular organismal signalingGO:0035637910.013
regulation of protein serine threonine kinase activityGO:00719001570.013
amide transportGO:00428861380.013
digestive system developmentGO:00551232000.013
ear developmentGO:00435832000.013
regulation of body fluid levelsGO:00508781620.013
negative regulation of phosphorylationGO:00423261660.013
epidermis developmentGO:00085441870.013
heart morphogenesisGO:00030071780.013
placenta developmentGO:00018901400.013
cell growthGO:00160491300.013
regulation of cell adhesionGO:00301551540.012
response to radiationGO:00093141650.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.012
interspecies interaction between organismsGO:0044419830.012
positive regulation of protein transportGO:0051222930.012
protein localization to organelleGO:00333651850.012
negative regulation of cytokine productionGO:0001818840.012
translationGO:0006412930.012
epithelial tube morphogenesisGO:00605623030.012
respiratory tube developmentGO:00303231670.012
cellular response to amino acid stimulusGO:0071230290.012
rna processingGO:00063961050.012
nucleotide catabolic processGO:00091662170.012
single organism cell adhesionGO:00986021560.012
response to inorganic substanceGO:0010035960.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
mitochondrion organizationGO:00070051340.012
cellular protein catabolic processGO:00442571550.012
leukocyte mediated cytotoxicityGO:0001909620.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
regulation of myeloid cell differentiationGO:0045637960.012
regulation of nucleotide metabolic processGO:00061401690.012
positive regulation of transforming growth factor beta secretionGO:200120310.012
hormone metabolic processGO:0042445860.012
cell fate commitmentGO:00451652100.012
tissue homeostasisGO:00018941150.012
muscle cell developmentGO:00550011330.012
response to peptide hormoneGO:00434341270.012
sensory organ morphogenesisGO:00905962420.012
carbohydrate homeostasisGO:00335001280.012
b cell differentiationGO:0030183780.012
myotube differentiationGO:00149021050.012
regulation of cellular component sizeGO:00325351210.012
regulation of myotube differentiationGO:0010830620.012
myeloid cell homeostasisGO:00022621140.012
transmission of nerve impulseGO:0019226760.012
hormone secretionGO:00468791280.012
multicellular organism growthGO:00352641610.012
negative regulation of protein phosphorylationGO:00019331260.012
covalent chromatin modificationGO:00165691630.012
morphogenesis of a branching epitheliumGO:00611381930.012
regulation of protein catabolic processGO:00421761080.012
regulation of protein complex assemblyGO:0043254830.012
organelle assemblyGO:00709251770.012
glycoprotein biosynthetic processGO:0009101890.012
extracellular structure organizationGO:00430621480.012
regulation of multi organism processGO:00439001110.012
protein targetingGO:00066051430.012
regulation of protein secretionGO:0050708820.011
germ cell developmentGO:00072811850.011
regulation of cellular response to stressGO:00801351590.011
bone developmentGO:00603481200.011
regulation of protein maturationGO:1903317960.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
axonogenesisGO:00074092740.011
organophosphate biosynthetic processGO:00904071220.011
negative regulation of lymphocyte activationGO:0051250910.011
regulation of cell cycle processGO:00105641600.011
locomotory behaviorGO:00076261950.011
skeletal system morphogenesisGO:00487052030.011
regulation of cell morphogenesis involved in differentiationGO:00107691510.011
myosin filament assemblyGO:003103420.011
retrograde transport endosome to golgiGO:004214720.011
alpha beta t cell activationGO:0046631910.011
regulation of ras protein signal transductionGO:00465781140.011
circulatory system processGO:00030131970.011
regulation of t cell proliferationGO:0042129920.011
regulation of bindingGO:00510981110.011
multi multicellular organism processGO:00447061090.011
nuclear divisionGO:00002801580.011
antigen receptor mediated signaling pathwayGO:0050851640.011
skin developmentGO:00435882200.011
negative regulation of cell developmentGO:00107211690.011
organic anion transportGO:00157111370.011
regulation of fat cell differentiationGO:0045598810.011
regulation of cytoskeleton organizationGO:00514931220.011
chromatin modificationGO:00165681870.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
cognitionGO:00508901490.011
positive regulation of neuron differentiationGO:00456661410.011
regulation of protein processingGO:0070613960.011
regionalizationGO:00030023370.011
negative regulation of apoptotic signaling pathwayGO:20012341040.011
proteasomal protein catabolic processGO:0010498980.011
developmental maturationGO:00217001930.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
wound healingGO:00420601570.011
peptide transportGO:00158331330.011
modification dependent macromolecule catabolic processGO:00436321330.011
positive regulation of cellular component biogenesisGO:0044089940.011
peptidyl tyrosine phosphorylationGO:00181081430.011
striated muscle myosin thick filament assemblyGO:007168810.011
cellular carbohydrate metabolic processGO:00442621190.011
mrna metabolic processGO:0016071840.011
urogenital system developmentGO:00016552610.011
regulation of lymphocyte mediated immunityGO:0002706840.011
meiotic nuclear divisionGO:00071261150.011
positive regulation of organelle organizationGO:00106381280.011
gtp catabolic processGO:00061841430.011
protein secretionGO:00093061110.011
regulation of metal ion transportGO:00109591060.011
microtubule cytoskeleton organizationGO:00002261570.011
small molecule biosynthetic processGO:00442831320.011
positive regulation of growthGO:00459271040.011
regulation of striated muscle cell differentiationGO:0051153810.011
developmental growth involved in morphogenesisGO:00605601380.011
response to amino acidGO:0043200370.011
calcium ion homeostasisGO:00550741270.011
gtp metabolic processGO:00460391440.010
divalent inorganic cation homeostasisGO:00725071380.010
cellular calcium ion homeostasisGO:00068741190.010
spermatid differentiationGO:00485151150.010
i kappab kinase nf kappab signalingGO:0007249850.010
positive regulation of cell projection organizationGO:0031346950.010
positive regulation of protein kinase activityGO:00458601440.010
negative regulation of hydrolase activityGO:0051346710.010
response to extracellular stimulusGO:00099911270.010
cell killingGO:0001906670.010
regulation of ossificationGO:00302781120.010
alcohol metabolic processGO:00060661160.010
regulation of wnt signaling pathwayGO:00301111230.010
response to light stimulusGO:00094161350.010
striated muscle cell developmentGO:00550021250.010
extracellular matrix organizationGO:00301981470.010
exocytosisGO:00068871210.010
positive regulation of purine nucleotide metabolic processGO:19005441140.010
renal system developmentGO:00720012250.010
organic hydroxy compound transportGO:0015850930.010
guanosine containing compound metabolic processGO:19010681440.010
single organismal cell cell adhesionGO:00163371310.010
regulation of nucleotide catabolic processGO:00308111220.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
learning or memoryGO:00076111480.010
response to oxygen levelsGO:0070482620.010
negative regulation of organelle organizationGO:0010639900.010
transition metal ion transportGO:0000041380.010

Trex1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
disease of metabolismDOID:001466700.012
central nervous system diseaseDOID:33100.010
sensory system diseaseDOID:005015500.010
eye diseaseDOID:561400.010
eye and adnexa diseaseDOID:149200.010