Mus musculus

25 known processes

Edem1

ER degradation enhancer, mannosidase alpha-like 1

(Aliases: KIAA0212,EDEM,A130059K23Rik,mKIAA0212)

Edem1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to endoplasmic reticulum stressGO:0034976530.483
response to unfolded proteinGO:0006986210.286
response to topologically incorrect proteinGO:0035966250.262
endoplasmic reticulum unfolded protein responseGO:0030968190.223
cellular response to topologically incorrect proteinGO:0035967250.158
glycoprotein metabolic processGO:00091001160.141
Mouse
glycosylationGO:0070085620.128
sphingolipid metabolic processGO:0006665450.127
transmembrane transportGO:00550854120.125
cellular response to biotic stimulusGO:0071216920.105
er nucleus signaling pathwayGO:0006984270.099
immune effector processGO:00022523210.097
cellular lipid metabolic processGO:00442553230.095
glycoprotein biosynthetic processGO:0009101890.092
ion transmembrane transportGO:00342203610.080
carbohydrate metabolic processGO:00059752300.079
inorganic ion transmembrane transportGO:00986602340.077
cytoplasmic transportGO:00164822340.076
macromolecule catabolic processGO:00090572810.076
nucleotide metabolic processGO:00091173320.075
cellular response to molecule of bacterial originGO:0071219830.073
cation transportGO:00068123990.072
positive regulation of cell activationGO:00508671580.072
apoptotic signaling pathwayGO:00971903060.069
cellular response to lipopolysaccharideGO:0071222770.068
carbohydrate derivative biosynthetic processGO:19011371830.066
positive regulation of cellular catabolic processGO:00313311480.064
regulation of cytokine productionGO:00018172660.064
male gamete generationGO:00482322850.064
regulation of proteolysisGO:00301621640.063
nitrogen compound transportGO:00717052710.063
macromolecule glycosylationGO:0043413550.061
cellular macromolecule catabolic processGO:00442652060.061
membrane lipid biosynthetic processGO:0046467320.059
positive regulation of proteolysisGO:0045862850.057
leukocyte mediated immunityGO:00024431740.057
ceramide metabolic processGO:0006672310.056
cytokine productionGO:00018163190.055
cation homeostasisGO:00550802120.055
cellular protein catabolic processGO:00442571550.055
cellular response to lipidGO:00713961450.054
regulation of cellular catabolic processGO:00313292420.052
ceramide biosynthetic processGO:0046513200.051
cellular amino acid metabolic processGO:00065201030.051
positive regulation of apoptotic signaling pathwayGO:2001235950.051
leukocyte differentiationGO:00025213420.050
spermatogenesisGO:00072832840.048
regulation of transferase activityGO:00513382630.048
membrane organizationGO:00610242450.047
immune response regulating signaling pathwayGO:00027641250.047
t cell differentiationGO:00302171740.047
respiratory system developmentGO:00605411900.047
regulation of hydrolase activityGO:00513362460.047
protein n linked glycosylationGO:0006487120.047
response to molecule of bacterial originGO:00022371430.046
regulation of cell activationGO:00508652890.045
respiratory tube developmentGO:00303231670.045
response to lipopolysaccharideGO:00324961280.045
regulation of apoptotic signaling pathwayGO:20012331970.044
protein glycosylationGO:0006486550.044
regulation of secretionGO:00510462740.044
nucleoside phosphate metabolic processGO:00067533380.043
amine metabolic processGO:0009308450.042
regulation of mapk cascadeGO:00434082480.041
regulation of cellular amino acid metabolic processGO:000652150.041
nucleobase containing small molecule metabolic processGO:00550863520.041
establishment of protein localization to organelleGO:00725941180.040
regulation of t cell activationGO:00508631700.040
b cell activationGO:00421131610.040
regulation of lymphocyte activationGO:00512492400.039
skin developmentGO:00435882200.039
regulation of cell projection organizationGO:00313442060.039
metal ion homeostasisGO:00550651890.039
mapk cascadeGO:00001652810.038
regulation of secretion by cellGO:19035302490.038
sequestering of metal ionGO:0051238190.038
regulation of homeostatic processGO:00328441820.037
cellular amine metabolic processGO:0044106440.037
leukocyte mediated cytotoxicityGO:0001909620.037
peptidyl amino acid modificationGO:00181933360.037
cellular ketone metabolic processGO:0042180840.036
gland developmentGO:00487323300.035
cation transmembrane transportGO:00986552660.035
carbohydrate derivative catabolic processGO:19011362310.035
Mouse
lateral inhibitionGO:004633110.035
cell killingGO:0001906670.035
inorganic cation transmembrane transportGO:00986622070.035
ribonucleotide metabolic processGO:00092592910.034
lymphocyte activation involved in immune responseGO:0002285930.034
cellular nitrogen compound catabolic processGO:00442702800.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.033
lymphocyte mediated immunityGO:00024491390.033
regulation of membrane potentialGO:00423911920.033
response to organic cyclic compoundGO:00140701980.032
endomembrane system organizationGO:00102561470.032
dephosphorylationGO:00163111290.032
organonitrogen compound biosynthetic processGO:19015661920.032
positive regulation of cell developmentGO:00107202370.032
organonitrogen compound catabolic processGO:19015652640.032
regulation of cellular ketone metabolic processGO:0010565660.032
anion transportGO:00068201770.031
maintenance of locationGO:0051235890.031
regulation of t cell differentiationGO:0045580830.031
posttranscriptional regulation of gene expressionGO:00106081550.031
positive regulation of programmed cell deathGO:00430682180.030
b cell differentiationGO:0030183780.030
regulation of kinase activityGO:00435492490.030
regulation of lymphocyte differentiationGO:00456191070.030
carbohydrate homeostasisGO:00335001280.030
positive regulation of growthGO:00459271040.030
purine ribonucleoside triphosphate metabolic processGO:00092052200.029
cellular chemical homeostasisGO:00550822150.029
adaptive immune responseGO:00022501550.029
innate immune responseGO:00450871570.029
positive regulation of cytokine productionGO:00018191740.029
oxidation reduction processGO:00551143420.029
regulation of interleukin 8 productionGO:003267730.028
negative regulation of phosphate metabolic processGO:00459361840.028
ribonucleoside triphosphate catabolic processGO:00092031990.028
transition metal ion homeostasisGO:0055076540.028
positive regulation of protein modification processGO:00314012990.027
lipid biosynthetic processGO:00086101790.027
cell activation involved in immune responseGO:00022631260.027
positive regulation of secretionGO:00510471300.027
positive regulation of cell deathGO:00109422240.027
regulation of transmembrane transportGO:00347621280.027
hepaticobiliary system developmentGO:0061008670.027
purine nucleoside triphosphate metabolic processGO:00091442260.027
t cell activationGO:00421102890.026
positive regulation of protein phosphorylationGO:00019342420.026
regulation of cellular response to stressGO:00801351590.026
action potentialGO:0001508780.026
positive regulation of hydrolase activityGO:00513451480.026
positive regulation of secretion by cellGO:19035321140.026
lung developmentGO:00303241640.026
positive regulation of apoptotic processGO:00430652170.026
cellular homeostasisGO:00197252400.025
intrinsic apoptotic signaling pathwayGO:00971931320.025
protein catabolic processGO:00301632210.024
immune response activating signal transductionGO:00027571160.024
response to interleukin 4GO:0070670230.024
positive regulation of membrane protein ectodomain proteolysisGO:005104430.024
establishment of protein localization to membraneGO:0090150540.024
lymphocyte differentiationGO:00300982420.024
negative regulation of intracellular signal transductionGO:19025321670.023
retina development in camera type eyeGO:00600411190.023
response to organonitrogen compoundGO:00102432460.023
intracellular protein transportGO:00068862040.023
organic hydroxy compound metabolic processGO:19016152030.022
protein localization to organelleGO:00333651850.022
interleukin 8 productionGO:003263740.022
regulation of establishment of protein localizationGO:00702011810.022
liver developmentGO:0001889660.022
regulation of cellular amine metabolic processGO:0033238200.022
muscle cell differentiationGO:00426922610.022
regulation of cellular protein catabolic processGO:1903362610.022
neurotransmitter secretionGO:0007269620.022
heterocycle catabolic processGO:00467002800.022
synaptic transmissionGO:00072683290.021
response to radiationGO:00093141650.021
peptide transportGO:00158331330.021
notch signaling pathwayGO:0007219710.021
glycosyl compound catabolic processGO:19016582060.021
positive regulation of cellular amine metabolic processGO:003324050.021
negative regulation of protein metabolic processGO:00512482820.021
protein autophosphorylationGO:0046777610.021
sphingolipid biosynthetic processGO:0030148260.021
organism emergence from protective structureGO:007168440.020
positive regulation of t cell activationGO:00508701010.020
ribonucleoside metabolic processGO:00091192450.020
purine nucleoside metabolic processGO:00422782410.020
nucleoside triphosphate catabolic processGO:00091432050.020
amide transportGO:00428861380.020
aromatic compound catabolic processGO:00194392860.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
cellular response to hormone stimulusGO:00328701500.020
regulation of cell adhesionGO:00301551540.020
positive regulation of protein secretionGO:0050714520.020
positive regulation of transferase activityGO:00513471670.019
positive regulation of immune effector processGO:00026991070.019
protein localization to membraneGO:00726571080.019
cellular ion homeostasisGO:00068731650.019
positive regulation of lymphocyte activationGO:00512511400.019
transition metal ion transportGO:0000041380.019
production of molecular mediator of immune responseGO:00024401030.019
interleukin 6 secretionGO:007260430.019
glucose homeostasisGO:00425931280.019
regulation of thymocyte migrationGO:200041020.019
monosaccharide metabolic processGO:00059961060.019
regulation of b cell differentiationGO:0045577230.019
mitochondrion organizationGO:00070051340.018
translationGO:0006412930.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
leukocyte activation involved in immune responseGO:00023661260.018
vacuole organizationGO:0007033380.018
positive regulation of t cell differentiationGO:0045582520.018
positive regulation of nervous system developmentGO:00519622210.018
regulation of neuron differentiationGO:00456642810.018
ribonucleoside catabolic processGO:00424542060.018
response to light stimulusGO:00094161350.018
ribose phosphate metabolic processGO:00196932910.018
response to drugGO:0042493750.018
t cell differentiation in thymusGO:0033077770.018
nucleoside metabolic processGO:00091162460.018
positive regulation of leukocyte differentiationGO:1902107860.018
purine ribonucleotide metabolic processGO:00091502900.018
cellular response to interleukin 4GO:0071353210.018
regulation of leukocyte differentiationGO:19021051590.018
regulation of neuron projection developmentGO:00109751690.017
positive regulation of growth hormone secretionGO:006012430.017
regulation of neurotransmitter levelsGO:0001505870.017
small gtpase mediated signal transductionGO:0007264970.017
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.017
epidermis developmentGO:00085441870.017
anatomical structure homeostasisGO:00602491450.017
response to acid chemicalGO:00011011110.017
regulation of ion transportGO:00432692150.017
regulation of interleukin 6 productionGO:0032675550.017
germ cell developmentGO:00072811850.017
multicellular organismal signalingGO:0035637910.016
regulation of leukocyte apoptotic processGO:2000106560.016
spermatid differentiationGO:00485151150.016
sensory organ morphogenesisGO:00905962420.016
protein modification by small protein conjugation or removalGO:00706472070.016
transmission of nerve impulseGO:0019226760.016
regulation of cell migrationGO:00303342190.016
reactive oxygen species metabolic processGO:0072593840.016
negative regulation of cellular protein metabolic processGO:00322692470.016
organic cyclic compound catabolic processGO:19013612950.016
purine nucleoside catabolic processGO:00061522050.016
leukocyte apoptotic processGO:0071887710.016
cell type specific apoptotic processGO:00972852680.016
protein targetingGO:00066051430.016
sphingolipid catabolic processGO:003014970.015
regulation of protein kinase activityGO:00458592320.015
purine containing compound metabolic processGO:00725213110.015
epithalamus developmentGO:002153820.015
membrane lipid metabolic processGO:0006643530.015
peptidyl tyrosine phosphorylationGO:00181081430.015
skeletal system developmentGO:00015013560.015
positive regulation of interleukin 8 productionGO:003275720.015
spermatid developmentGO:00072861080.015
cellular metal ion homeostasisGO:00068751510.015
male sex differentiationGO:00466611090.015
peptidyl tyrosine modificationGO:00182121450.015
negative regulation of cellular amino acid metabolic processGO:004576300.015
establishment of synaptic vesicle localizationGO:0097480570.015
protein ubiquitinationGO:00165671710.015
positive regulation of cell adhesionGO:0045785800.015
immune response regulating cell surface receptor signaling pathwayGO:0002768800.015
activation of immune responseGO:00022531380.015
establishment of vesicle localizationGO:0051650810.015
cell growthGO:00160491300.015
glycosyl compound metabolic processGO:19016572460.015
lipid transportGO:0006869980.015
regulation of ion transmembrane transportGO:00347651190.015
prevention of polyspermyGO:006046840.014
b cell activation involved in immune responseGO:0002312500.014
divalent inorganic cation transportGO:00725111780.014
epithelial cell developmentGO:00020641590.014
multicellular organismal agingGO:0010259240.014
immune response activating cell surface receptor signaling pathwayGO:0002429720.014
small molecule biosynthetic processGO:00442831320.014
gtp metabolic processGO:00460391440.014
camera type eye developmentGO:00430102660.014
divalent metal ion transportGO:00708381720.014
extracellular matrix dependent thymocyte migrationGO:007268010.014
guanosine containing compound metabolic processGO:19010681440.014
antigen receptor mediated signaling pathwayGO:0050851640.014
neural tube formationGO:00018411080.014
positive regulation of purine nucleotide metabolic processGO:19005441140.014
negative regulation of molecular functionGO:00440922580.014
compound eye developmentGO:004874910.014
purine nucleotide metabolic processGO:00061633020.014
lipid localizationGO:00108761260.014
positive regulation of interleukin 6 secretionGO:200077810.014
positive regulation of mapk cascadeGO:00434101700.014
positive regulation of cellular protein catabolic processGO:1903364340.014
regulation of leukocyte mediated cytotoxicityGO:0001910380.014
cellular response to cytokine stimulusGO:00713451890.014
organelle localizationGO:00516401790.014
negative regulation of phosphorus metabolic processGO:00105631840.014
regulation of cell motilityGO:20001452360.014
regulation of hormone levelsGO:00108172110.014
positive regulation of lymphocyte differentiationGO:0045621610.013
leukocyte homeostasisGO:0001776790.013
regulation of peptide transportGO:0090087910.013
hormone secretionGO:00468791280.013
regulation of antigen receptor mediated signaling pathwayGO:0050854290.013
regulation of body fluid levelsGO:00508781620.013
ensheathment of neuronsGO:0007272760.013
regulation of production of molecular mediator of immune responseGO:0002700650.013
regulation of map kinase activityGO:00434051200.013
regulation of protein catabolic processGO:00421761080.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
negative regulation of phosphorylationGO:00423261660.013
stress activated mapk cascadeGO:0051403800.013
purine ribonucleoside metabolic processGO:00461282410.013
protein oligomerizationGO:0051259670.013
lymphocyte apoptotic processGO:0070227540.013
peptide hormone secretionGO:00300721090.013
insulin secretionGO:0030073890.013
positive regulation of protein catabolic processGO:0045732600.013
positive regulation of neuron differentiationGO:00456661410.013
regulation of erk1 and erk2 cascadeGO:0070372710.013
single organism cell adhesionGO:00986021560.013
endocytosisGO:00068971680.013
ribonucleotide catabolic processGO:00092612080.013
interleukin 6 productionGO:0032635580.013
organic hydroxy compound transportGO:0015850930.013
regulation of organelle organizationGO:00330432890.013
protein targeting to erGO:004504720.013
nucleotide biosynthetic processGO:0009165780.013
proteasomal protein catabolic processGO:0010498980.013
cellular response to growth factor stimulusGO:00713631970.013
sphingosine metabolic processGO:000667040.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
protein localization to vacuoleGO:007266540.013
response to inorganic substanceGO:0010035960.012
defecationGO:003042110.012
mrna metabolic processGO:0016071840.012
myelinationGO:0042552740.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
multicellular organismal homeostasisGO:00488711640.012
sensory perceptionGO:00076002450.012
cellular transition metal ion homeostasisGO:0046916320.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
positive regulation of interleukin 6 productionGO:0032755370.012
organophosphate biosynthetic processGO:00904071220.012
nucleoside catabolic processGO:00091642060.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.012
cellular response to external stimulusGO:0071496880.012
positive regulation of defense responseGO:00313491240.012
fat cell differentiationGO:00454441600.012
regulation of myeloid cell differentiationGO:0045637960.012
plasma cell differentiationGO:000231730.012
blood vessel morphogenesisGO:00485142850.012
negative regulation of cellular amine metabolic processGO:003323910.012
positive regulation of kinase activityGO:00336741550.012
exocytosisGO:00068871210.012
rho protein signal transductionGO:0007266320.012
homeostasis of number of cellsGO:00488722100.012
purine ribonucleoside catabolic processGO:00461302050.012
regulation of cellular component biogenesisGO:00440871810.012
cellularizationGO:000734910.012
neurotransmitter transportGO:0006836760.012
chemotaxisGO:00069352470.012
cellular protein complex assemblyGO:00436231160.012
steroid metabolic processGO:00082021190.012
digestive tract developmentGO:00485651900.012
hatchingGO:003518840.012
positive regulation of protein kinase activityGO:00458601440.011
regulation of nucleotide metabolic processGO:00061401690.011
adult locomotory behaviorGO:0008344910.011
developmental maturationGO:00217001930.011
establishment of protein localization to vacuoleGO:007266640.011
engulfment of apoptotic cellGO:004365230.011
axonogenesisGO:00074092740.011
renal system developmentGO:00720012250.011
neutral lipid metabolic processGO:0006638570.011
regulation of b cell activationGO:0050864810.011
sequestering of calcium ionGO:0051208180.011
organ growthGO:00352651170.011
adult behaviorGO:00305341350.011
blood circulationGO:00080151950.011
protein targeting to membraneGO:0006612200.011
positive regulation of map kinase activityGO:0043406840.011
regulation of neuron deathGO:19012141340.011
t cell mediated cytotoxicityGO:0001913260.011
anion transmembrane transportGO:0098656710.011
regulation of neuron apoptotic processGO:00435231220.011
neuron deathGO:00709971540.011
axon ensheathmentGO:0008366760.011
regulation of system processGO:00440572000.011
nucleoside phosphate catabolic processGO:19012922220.011
positive regulation of nucleotide metabolic processGO:00459811140.011
regulation of lymphocyte apoptotic processGO:0070228410.011
cell substrate adhesionGO:00315891300.011
meiotic cell cycleGO:00513211220.011
intra golgi vesicle mediated transportGO:000689110.011
regulation of cell killingGO:0031341400.011
pigmentationGO:0043473710.011
positive regulation of b cell activationGO:0050871490.011
cellular response to organonitrogen compoundGO:00714171450.011
t cell mediated immunityGO:0002456500.011
multicellular organism growthGO:00352641610.011
monocarboxylic acid metabolic processGO:00327871910.011
organic hydroxy compound biosynthetic processGO:1901617770.011
purine containing compound catabolic processGO:00725232130.011
extracellular matrix organizationGO:00301981470.011
positive regulation of nucleoside metabolic processGO:0045979910.011
wound healingGO:00420601570.011
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.011
urogenital system developmentGO:00016552610.011
angiogenesisGO:00015252010.010
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.010
synaptic vesicle localizationGO:0097479590.010
learning or memoryGO:00076111480.010
myeloid cell differentiationGO:00300992330.010
synaptic vesicle transportGO:0048489570.010
alcohol biosynthetic processGO:0046165430.010
cell matrix adhesionGO:0007160680.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
regulation of peptidyl tyrosine phosphorylationGO:0050730930.010
vesicle localizationGO:0051648860.010
regulation of eosinophil migrationGO:200041620.010
nucleotide catabolic processGO:00091662170.010
defense response to bacteriumGO:00427421190.010
response to tumor necrosis factorGO:0034612260.010
regulation of response to woundingGO:19030341890.010
nuclear transportGO:00511691390.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010

Edem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.089
disease of anatomical entityDOID:700.089
inherited metabolic disorderDOID:65500.083
disease of metabolismDOID:001466700.083
disease of cellular proliferationDOID:1456600.028
cancerDOID:16200.028
neuropathyDOID:87000.014
carbohydrate metabolic disorderDOID:297800.013
organ system cancerDOID:005068600.012
sensory system diseaseDOID:005015500.012
immune system diseaseDOID:291400.012
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
retinal diseaseDOID:567900.010
immune system cancerDOID:006008300.010