IMP: Integrative Multi-species Prediction

Mus musculus

25 known processes

Edem1

ER degradation enhancer, mannosidase alpha-like 1

(Aliases: KIAA0212,EDEM,A130059K23Rik,mKIAA0212)

Entrez: 192193
Ensembl: ENSMUSG00000030104
UniProtKB: Q925U4

Process Predictions
Disease Predictions

Edem1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to endoplasmic reticulum stress	GO:0034976	53	0.483
response to unfolded protein	GO:0006986	21	0.286
response to topologically incorrect protein	GO:0035966	25	0.262
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.223
cellular response to topologically incorrect protein	GO:0035967	25	0.158
glycoprotein metabolic process	GO:0009100	116	0.141	Mouse
glycosylation	GO:0070085	62	0.128
sphingolipid metabolic process	GO:0006665	45	0.127
transmembrane transport	GO:0055085	412	0.125
cellular response to biotic stimulus	GO:0071216	92	0.105
er nucleus signaling pathway	GO:0006984	27	0.099
immune effector process	GO:0002252	321	0.097
cellular lipid metabolic process	GO:0044255	323	0.095
glycoprotein biosynthetic process	GO:0009101	89	0.092
ion transmembrane transport	GO:0034220	361	0.080
carbohydrate metabolic process	GO:0005975	230	0.079
inorganic ion transmembrane transport	GO:0098660	234	0.077
cytoplasmic transport	GO:0016482	234	0.076
macromolecule catabolic process	GO:0009057	281	0.076
nucleotide metabolic process	GO:0009117	332	0.075
cellular response to molecule of bacterial origin	GO:0071219	83	0.073
cation transport	GO:0006812	399	0.072
positive regulation of cell activation	GO:0050867	158	0.072
apoptotic signaling pathway	GO:0097190	306	0.069
cellular response to lipopolysaccharide	GO:0071222	77	0.068
carbohydrate derivative biosynthetic process	GO:1901137	183	0.066
positive regulation of cellular catabolic process	GO:0031331	148	0.064
regulation of cytokine production	GO:0001817	266	0.064
male gamete generation	GO:0048232	285	0.064
regulation of proteolysis	GO:0030162	164	0.063
nitrogen compound transport	GO:0071705	271	0.063
macromolecule glycosylation	GO:0043413	55	0.061
cellular macromolecule catabolic process	GO:0044265	206	0.061
membrane lipid biosynthetic process	GO:0046467	32	0.059
positive regulation of proteolysis	GO:0045862	85	0.057
leukocyte mediated immunity	GO:0002443	174	0.057
ceramide metabolic process	GO:0006672	31	0.056
cytokine production	GO:0001816	319	0.055
cation homeostasis	GO:0055080	212	0.055
cellular protein catabolic process	GO:0044257	155	0.055
cellular response to lipid	GO:0071396	145	0.054
regulation of cellular catabolic process	GO:0031329	242	0.052
ceramide biosynthetic process	GO:0046513	20	0.051
cellular amino acid metabolic process	GO:0006520	103	0.051
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.051
leukocyte differentiation	GO:0002521	342	0.050
spermatogenesis	GO:0007283	284	0.048
regulation of transferase activity	GO:0051338	263	0.048
membrane organization	GO:0061024	245	0.047
immune response regulating signaling pathway	GO:0002764	125	0.047
t cell differentiation	GO:0030217	174	0.047
respiratory system development	GO:0060541	190	0.047
regulation of hydrolase activity	GO:0051336	246	0.047
protein n linked glycosylation	GO:0006487	12	0.047
response to molecule of bacterial origin	GO:0002237	143	0.046
regulation of cell activation	GO:0050865	289	0.045
respiratory tube development	GO:0030323	167	0.045
response to lipopolysaccharide	GO:0032496	128	0.045
regulation of apoptotic signaling pathway	GO:2001233	197	0.044
protein glycosylation	GO:0006486	55	0.044
regulation of secretion	GO:0051046	274	0.044
nucleoside phosphate metabolic process	GO:0006753	338	0.043
amine metabolic process	GO:0009308	45	0.042
regulation of mapk cascade	GO:0043408	248	0.041
regulation of cellular amino acid metabolic process	GO:0006521	5	0.041
nucleobase containing small molecule metabolic process	GO:0055086	352	0.041
establishment of protein localization to organelle	GO:0072594	118	0.040
regulation of t cell activation	GO:0050863	170	0.040
b cell activation	GO:0042113	161	0.040
regulation of lymphocyte activation	GO:0051249	240	0.039
skin development	GO:0043588	220	0.039
regulation of cell projection organization	GO:0031344	206	0.039
metal ion homeostasis	GO:0055065	189	0.039
mapk cascade	GO:0000165	281	0.038
regulation of secretion by cell	GO:1903530	249	0.038
sequestering of metal ion	GO:0051238	19	0.038
regulation of homeostatic process	GO:0032844	182	0.037
cellular amine metabolic process	GO:0044106	44	0.037
leukocyte mediated cytotoxicity	GO:0001909	62	0.037
peptidyl amino acid modification	GO:0018193	336	0.037
cellular ketone metabolic process	GO:0042180	84	0.036
gland development	GO:0048732	330	0.035
cation transmembrane transport	GO:0098655	266	0.035
carbohydrate derivative catabolic process	GO:1901136	231	0.035	Mouse
lateral inhibition	GO:0046331	1	0.035
cell killing	GO:0001906	67	0.035
inorganic cation transmembrane transport	GO:0098662	207	0.035
ribonucleotide metabolic process	GO:0009259	291	0.034
lymphocyte activation involved in immune response	GO:0002285	93	0.034
cellular nitrogen compound catabolic process	GO:0044270	280	0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.033
lymphocyte mediated immunity	GO:0002449	139	0.033
regulation of membrane potential	GO:0042391	192	0.033
response to organic cyclic compound	GO:0014070	198	0.032
endomembrane system organization	GO:0010256	147	0.032
dephosphorylation	GO:0016311	129	0.032
organonitrogen compound biosynthetic process	GO:1901566	192	0.032
positive regulation of cell development	GO:0010720	237	0.032
organonitrogen compound catabolic process	GO:1901565	264	0.032
regulation of cellular ketone metabolic process	GO:0010565	66	0.032
anion transport	GO:0006820	177	0.031
maintenance of location	GO:0051235	89	0.031
regulation of t cell differentiation	GO:0045580	83	0.031
posttranscriptional regulation of gene expression	GO:0010608	155	0.031
positive regulation of programmed cell death	GO:0043068	218	0.030
b cell differentiation	GO:0030183	78	0.030
regulation of kinase activity	GO:0043549	249	0.030
regulation of lymphocyte differentiation	GO:0045619	107	0.030
carbohydrate homeostasis	GO:0033500	128	0.030
positive regulation of growth	GO:0045927	104	0.030
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.029
cellular chemical homeostasis	GO:0055082	215	0.029
adaptive immune response	GO:0002250	155	0.029
innate immune response	GO:0045087	157	0.029
positive regulation of cytokine production	GO:0001819	174	0.029
oxidation reduction process	GO:0055114	342	0.029
regulation of interleukin 8 production	GO:0032677	3	0.028
negative regulation of phosphate metabolic process	GO:0045936	184	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.028
transition metal ion homeostasis	GO:0055076	54	0.028
positive regulation of protein modification process	GO:0031401	299	0.027
lipid biosynthetic process	GO:0008610	179	0.027
cell activation involved in immune response	GO:0002263	126	0.027
positive regulation of secretion	GO:0051047	130	0.027
positive regulation of cell death	GO:0010942	224	0.027
regulation of transmembrane transport	GO:0034762	128	0.027
hepaticobiliary system development	GO:0061008	67	0.027
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.027
t cell activation	GO:0042110	289	0.026
positive regulation of protein phosphorylation	GO:0001934	242	0.026
regulation of cellular response to stress	GO:0080135	159	0.026
action potential	GO:0001508	78	0.026
positive regulation of hydrolase activity	GO:0051345	148	0.026
positive regulation of secretion by cell	GO:1903532	114	0.026
lung development	GO:0030324	164	0.026
positive regulation of apoptotic process	GO:0043065	217	0.026
cellular homeostasis	GO:0019725	240	0.025
intrinsic apoptotic signaling pathway	GO:0097193	132	0.025
protein catabolic process	GO:0030163	221	0.024
immune response activating signal transduction	GO:0002757	116	0.024
response to interleukin 4	GO:0070670	23	0.024
positive regulation of membrane protein ectodomain proteolysis	GO:0051044	3	0.024
establishment of protein localization to membrane	GO:0090150	54	0.024
lymphocyte differentiation	GO:0030098	242	0.024
negative regulation of intracellular signal transduction	GO:1902532	167	0.023
retina development in camera type eye	GO:0060041	119	0.023
response to organonitrogen compound	GO:0010243	246	0.023
intracellular protein transport	GO:0006886	204	0.023
organic hydroxy compound metabolic process	GO:1901615	203	0.022
protein localization to organelle	GO:0033365	185	0.022
interleukin 8 production	GO:0032637	4	0.022
regulation of establishment of protein localization	GO:0070201	181	0.022
liver development	GO:0001889	66	0.022
regulation of cellular amine metabolic process	GO:0033238	20	0.022
muscle cell differentiation	GO:0042692	261	0.022
regulation of cellular protein catabolic process	GO:1903362	61	0.022
neurotransmitter secretion	GO:0007269	62	0.022
heterocycle catabolic process	GO:0046700	280	0.022
synaptic transmission	GO:0007268	329	0.021
response to radiation	GO:0009314	165	0.021
peptide transport	GO:0015833	133	0.021
notch signaling pathway	GO:0007219	71	0.021
glycosyl compound catabolic process	GO:1901658	206	0.021
positive regulation of cellular amine metabolic process	GO:0033240	5	0.021
negative regulation of protein metabolic process	GO:0051248	282	0.021
protein autophosphorylation	GO:0046777	61	0.021
sphingolipid biosynthetic process	GO:0030148	26	0.021
organism emergence from protective structure	GO:0071684	4	0.020
positive regulation of t cell activation	GO:0050870	101	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
purine nucleoside metabolic process	GO:0042278	241	0.020
nucleoside triphosphate catabolic process	GO:0009143	205	0.020
amide transport	GO:0042886	138	0.020
aromatic compound catabolic process	GO:0019439	286	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.020
cellular response to hormone stimulus	GO:0032870	150	0.020
regulation of cell adhesion	GO:0030155	154	0.020
positive regulation of protein secretion	GO:0050714	52	0.020
positive regulation of transferase activity	GO:0051347	167	0.019
positive regulation of immune effector process	GO:0002699	107	0.019
protein localization to membrane	GO:0072657	108	0.019
cellular ion homeostasis	GO:0006873	165	0.019
positive regulation of lymphocyte activation	GO:0051251	140	0.019
transition metal ion transport	GO:0000041	38	0.019
production of molecular mediator of immune response	GO:0002440	103	0.019
interleukin 6 secretion	GO:0072604	3	0.019
glucose homeostasis	GO:0042593	128	0.019
regulation of thymocyte migration	GO:2000410	2	0.019
monosaccharide metabolic process	GO:0005996	106	0.019
regulation of b cell differentiation	GO:0045577	23	0.019
mitochondrion organization	GO:0007005	134	0.018
translation	GO:0006412	93	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.018
leukocyte activation involved in immune response	GO:0002366	126	0.018
vacuole organization	GO:0007033	38	0.018
positive regulation of t cell differentiation	GO:0045582	52	0.018
positive regulation of nervous system development	GO:0051962	221	0.018
regulation of neuron differentiation	GO:0045664	281	0.018
ribonucleoside catabolic process	GO:0042454	206	0.018
response to light stimulus	GO:0009416	135	0.018
ribose phosphate metabolic process	GO:0019693	291	0.018
response to drug	GO:0042493	75	0.018
t cell differentiation in thymus	GO:0033077	77	0.018
nucleoside metabolic process	GO:0009116	246	0.018
positive regulation of leukocyte differentiation	GO:1902107	86	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.018
cellular response to interleukin 4	GO:0071353	21	0.018
regulation of leukocyte differentiation	GO:1902105	159	0.018
regulation of neuron projection development	GO:0010975	169	0.017
positive regulation of growth hormone secretion	GO:0060124	3	0.017
regulation of neurotransmitter levels	GO:0001505	87	0.017
small gtpase mediated signal transduction	GO:0007264	97	0.017
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	68	0.017
epidermis development	GO:0008544	187	0.017
anatomical structure homeostasis	GO:0060249	145	0.017
response to acid chemical	GO:0001101	111	0.017
regulation of ion transport	GO:0043269	215	0.017
regulation of interleukin 6 production	GO:0032675	55	0.017
germ cell development	GO:0007281	185	0.017
multicellular organismal signaling	GO:0035637	91	0.016
regulation of leukocyte apoptotic process	GO:2000106	56	0.016
spermatid differentiation	GO:0048515	115	0.016
sensory organ morphogenesis	GO:0090596	242	0.016
protein modification by small protein conjugation or removal	GO:0070647	207	0.016
transmission of nerve impulse	GO:0019226	76	0.016
regulation of cell migration	GO:0030334	219	0.016
reactive oxygen species metabolic process	GO:0072593	84	0.016
negative regulation of cellular protein metabolic process	GO:0032269	247	0.016
organic cyclic compound catabolic process	GO:1901361	295	0.016
purine nucleoside catabolic process	GO:0006152	205	0.016
leukocyte apoptotic process	GO:0071887	71	0.016
cell type specific apoptotic process	GO:0097285	268	0.016
protein targeting	GO:0006605	143	0.016
sphingolipid catabolic process	GO:0030149	7	0.015
regulation of protein kinase activity	GO:0045859	232	0.015
purine containing compound metabolic process	GO:0072521	311	0.015
epithalamus development	GO:0021538	2	0.015
membrane lipid metabolic process	GO:0006643	53	0.015
peptidyl tyrosine phosphorylation	GO:0018108	143	0.015
skeletal system development	GO:0001501	356	0.015
positive regulation of interleukin 8 production	GO:0032757	2	0.015
spermatid development	GO:0007286	108	0.015
cellular metal ion homeostasis	GO:0006875	151	0.015
male sex differentiation	GO:0046661	109	0.015
peptidyl tyrosine modification	GO:0018212	145	0.015
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.015
establishment of synaptic vesicle localization	GO:0097480	57	0.015
protein ubiquitination	GO:0016567	171	0.015
positive regulation of cell adhesion	GO:0045785	80	0.015
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.015
activation of immune response	GO:0002253	138	0.015
establishment of vesicle localization	GO:0051650	81	0.015
cell growth	GO:0016049	130	0.015
glycosyl compound metabolic process	GO:1901657	246	0.015
lipid transport	GO:0006869	98	0.015
regulation of ion transmembrane transport	GO:0034765	119	0.015
prevention of polyspermy	GO:0060468	4	0.014
b cell activation involved in immune response	GO:0002312	50	0.014
divalent inorganic cation transport	GO:0072511	178	0.014
epithelial cell development	GO:0002064	159	0.014
multicellular organismal aging	GO:0010259	24	0.014
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.014
small molecule biosynthetic process	GO:0044283	132	0.014
gtp metabolic process	GO:0046039	144	0.014
camera type eye development	GO:0043010	266	0.014
divalent metal ion transport	GO:0070838	172	0.014
extracellular matrix dependent thymocyte migration	GO:0072680	1	0.014
guanosine containing compound metabolic process	GO:1901068	144	0.014
antigen receptor mediated signaling pathway	GO:0050851	64	0.014
neural tube formation	GO:0001841	108	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.014
negative regulation of molecular function	GO:0044092	258	0.014
compound eye development	GO:0048749	1	0.014
purine nucleotide metabolic process	GO:0006163	302	0.014
lipid localization	GO:0010876	126	0.014
positive regulation of interleukin 6 secretion	GO:2000778	1	0.014
positive regulation of mapk cascade	GO:0043410	170	0.014
positive regulation of cellular protein catabolic process	GO:1903364	34	0.014
regulation of leukocyte mediated cytotoxicity	GO:0001910	38	0.014
cellular response to cytokine stimulus	GO:0071345	189	0.014
organelle localization	GO:0051640	179	0.014
negative regulation of phosphorus metabolic process	GO:0010563	184	0.014
regulation of cell motility	GO:2000145	236	0.014
regulation of hormone levels	GO:0010817	211	0.014
positive regulation of lymphocyte differentiation	GO:0045621	61	0.013
leukocyte homeostasis	GO:0001776	79	0.013
regulation of peptide transport	GO:0090087	91	0.013
hormone secretion	GO:0046879	128	0.013
regulation of antigen receptor mediated signaling pathway	GO:0050854	29	0.013
regulation of body fluid levels	GO:0050878	162	0.013
ensheathment of neurons	GO:0007272	76	0.013
regulation of production of molecular mediator of immune response	GO:0002700	65	0.013
regulation of map kinase activity	GO:0043405	120	0.013
regulation of protein catabolic process	GO:0042176	108	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.013
negative regulation of phosphorylation	GO:0042326	166	0.013
stress activated mapk cascade	GO:0051403	80	0.013
purine ribonucleoside metabolic process	GO:0046128	241	0.013
protein oligomerization	GO:0051259	67	0.013
lymphocyte apoptotic process	GO:0070227	54	0.013
peptide hormone secretion	GO:0030072	109	0.013
insulin secretion	GO:0030073	89	0.013
positive regulation of protein catabolic process	GO:0045732	60	0.013
positive regulation of neuron differentiation	GO:0045666	141	0.013
regulation of erk1 and erk2 cascade	GO:0070372	71	0.013
single organism cell adhesion	GO:0098602	156	0.013
endocytosis	GO:0006897	168	0.013
ribonucleotide catabolic process	GO:0009261	208	0.013
interleukin 6 production	GO:0032635	58	0.013
organic hydroxy compound transport	GO:0015850	93	0.013
regulation of organelle organization	GO:0033043	289	0.013
protein targeting to er	GO:0045047	2	0.013
nucleotide biosynthetic process	GO:0009165	78	0.013
proteasomal protein catabolic process	GO:0010498	98	0.013
cellular response to growth factor stimulus	GO:0071363	197	0.013
sphingosine metabolic process	GO:0006670	4	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.013
protein localization to vacuole	GO:0072665	4	0.013
response to inorganic substance	GO:0010035	96	0.012
defecation	GO:0030421	1	0.012
mrna metabolic process	GO:0016071	84	0.012
myelination	GO:0042552	74	0.012
extrinsic apoptotic signaling pathway	GO:0097191	126	0.012
multicellular organismal homeostasis	GO:0048871	164	0.012
sensory perception	GO:0007600	245	0.012
cellular transition metal ion homeostasis	GO:0046916	32	0.012
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
positive regulation of interleukin 6 production	GO:0032755	37	0.012
organophosphate biosynthetic process	GO:0090407	122	0.012
nucleoside catabolic process	GO:0009164	206	0.012
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	31	0.012
cellular response to external stimulus	GO:0071496	88	0.012
positive regulation of defense response	GO:0031349	124	0.012
fat cell differentiation	GO:0045444	160	0.012
regulation of myeloid cell differentiation	GO:0045637	96	0.012
plasma cell differentiation	GO:0002317	3	0.012
blood vessel morphogenesis	GO:0048514	285	0.012
negative regulation of cellular amine metabolic process	GO:0033239	1	0.012
positive regulation of kinase activity	GO:0033674	155	0.012
exocytosis	GO:0006887	121	0.012
rho protein signal transduction	GO:0007266	32	0.012
homeostasis of number of cells	GO:0048872	210	0.012
purine ribonucleoside catabolic process	GO:0046130	205	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
cellularization	GO:0007349	1	0.012
neurotransmitter transport	GO:0006836	76	0.012
chemotaxis	GO:0006935	247	0.012
cellular protein complex assembly	GO:0043623	116	0.012
steroid metabolic process	GO:0008202	119	0.012
digestive tract development	GO:0048565	190	0.012
hatching	GO:0035188	4	0.012
positive regulation of protein kinase activity	GO:0045860	144	0.011
regulation of nucleotide metabolic process	GO:0006140	169	0.011
adult locomotory behavior	GO:0008344	91	0.011
developmental maturation	GO:0021700	193	0.011
establishment of protein localization to vacuole	GO:0072666	4	0.011
engulfment of apoptotic cell	GO:0043652	3	0.011
axonogenesis	GO:0007409	274	0.011
renal system development	GO:0072001	225	0.011
neutral lipid metabolic process	GO:0006638	57	0.011
regulation of b cell activation	GO:0050864	81	0.011
sequestering of calcium ion	GO:0051208	18	0.011
organ growth	GO:0035265	117	0.011
adult behavior	GO:0030534	135	0.011
blood circulation	GO:0008015	195	0.011
protein targeting to membrane	GO:0006612	20	0.011
positive regulation of map kinase activity	GO:0043406	84	0.011
regulation of neuron death	GO:1901214	134	0.011
t cell mediated cytotoxicity	GO:0001913	26	0.011
anion transmembrane transport	GO:0098656	71	0.011
regulation of neuron apoptotic process	GO:0043523	122	0.011
neuron death	GO:0070997	154	0.011
axon ensheathment	GO:0008366	76	0.011
regulation of system process	GO:0044057	200	0.011
nucleoside phosphate catabolic process	GO:1901292	222	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
regulation of lymphocyte apoptotic process	GO:0070228	41	0.011
cell substrate adhesion	GO:0031589	130	0.011
meiotic cell cycle	GO:0051321	122	0.011
intra golgi vesicle mediated transport	GO:0006891	1	0.011
regulation of cell killing	GO:0031341	40	0.011
pigmentation	GO:0043473	71	0.011
positive regulation of b cell activation	GO:0050871	49	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
t cell mediated immunity	GO:0002456	50	0.011
multicellular organism growth	GO:0035264	161	0.011
monocarboxylic acid metabolic process	GO:0032787	191	0.011
organic hydroxy compound biosynthetic process	GO:1901617	77	0.011
purine containing compound catabolic process	GO:0072523	213	0.011
extracellular matrix organization	GO:0030198	147	0.011
positive regulation of nucleoside metabolic process	GO:0045979	91	0.011
wound healing	GO:0042060	157	0.011
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	34	0.011
urogenital system development	GO:0001655	261	0.011
angiogenesis	GO:0001525	201	0.010
regulation of tumor necrosis factor ligand superfamily member 11 production	GO:2000307	1	0.010
synaptic vesicle localization	GO:0097479	59	0.010
learning or memory	GO:0007611	148	0.010
myeloid cell differentiation	GO:0030099	233	0.010
synaptic vesicle transport	GO:0048489	57	0.010
alcohol biosynthetic process	GO:0046165	43	0.010
cell matrix adhesion	GO:0007160	68	0.010
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.010
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.010
vesicle localization	GO:0051648	86	0.010
regulation of eosinophil migration	GO:2000416	2	0.010
nucleotide catabolic process	GO:0009166	217	0.010
defense response to bacterium	GO:0042742	119	0.010
response to tumor necrosis factor	GO:0034612	26	0.010
regulation of response to wounding	GO:1903034	189	0.010
nuclear transport	GO:0051169	139	0.010
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.010

Edem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.089
disease of anatomical entity	DOID:7	0.089
inherited metabolic disorder	DOID:655	0.083
disease of metabolism	DOID:0014667	0.083
disease of cellular proliferation	DOID:14566	0.028
cancer	DOID:162	0.028
neuropathy	DOID:870	0.014
carbohydrate metabolic disorder	DOID:2978	0.013
organ system cancer	DOID:0050686	0.012
sensory system disease	DOID:0050155	0.012
immune system disease	DOID:2914	0.012
eye and adnexa disease	DOID:1492	0.011
eye disease	DOID:5614	0.011
retinal disease	DOID:5679	0.010
immune system cancer	DOID:0060083	0.010

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Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network