Mus musculus

16 known processes

Me1

malic enzyme 1, NADP(+)-dependent, cytosolic

(Aliases: MGC91072,Mod1,Mdh-1,D9Ertd267e,Mod-1)

Me1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553230.231
oxidation reduction processGO:00551143420.129
monocarboxylic acid metabolic processGO:00327871910.128
cellular amino acid metabolic processGO:00065201030.093
cofactor metabolic processGO:0051186800.092
lipid biosynthetic processGO:00086101790.092
cellular ketone metabolic processGO:0042180840.078
glycerolipid metabolic processGO:00464861220.065
cellular amine metabolic processGO:0044106440.062
amine metabolic processGO:0009308450.061
regulation of cellular ketone metabolic processGO:0010565660.059
nucleotide metabolic processGO:00091173320.058
nucleoside phosphate metabolic processGO:00067533380.050
small molecule biosynthetic processGO:00442831320.049
transmembrane transportGO:00550854120.049
fatty acid metabolic processGO:00066311210.048
regulation of cellular catabolic processGO:00313292420.047
coenzyme metabolic processGO:0006732520.046
organic hydroxy compound metabolic processGO:19016152030.045
anion transportGO:00068201770.042
sulfur compound metabolic processGO:00067901000.042
organonitrogen compound biosynthetic processGO:19015661920.041
positive regulation of cellular amino acid metabolic processGO:004576430.040
ribose phosphate metabolic processGO:00196932910.040
carbohydrate metabolic processGO:00059752300.039
nucleobase containing small molecule metabolic processGO:00550863520.038
organonitrogen compound catabolic processGO:19015652640.036
response to oxidative stressGO:00069791230.035
positive regulation of cellular amine metabolic processGO:003324050.035
regulation of cellular amino acid metabolic processGO:000652150.034
purine containing compound metabolic processGO:00725213110.033
alcohol metabolic processGO:00060661160.033
spermatogenesisGO:00072832840.033
carboxylic acid biosynthetic processGO:0046394860.033
macromolecule catabolic processGO:00090572810.032
monocarboxylic acid biosynthetic processGO:0072330610.032
nucleoside metabolic processGO:00091162460.031
purine ribonucleoside metabolic processGO:00461282410.031
male gamete generationGO:00482322850.030
ion transmembrane transportGO:00342203610.030
regulation of cellular amine metabolic processGO:0033238200.030
glycerolipid biosynthetic processGO:0045017500.030
ras protein signal transductionGO:0007265770.030
protein catabolic processGO:00301632210.030
regulation of membrane potentialGO:00423911920.029
posttranscriptional regulation of gene expressionGO:00106081550.029
neutral lipid metabolic processGO:0006638570.029
negative regulation of phosphorus metabolic processGO:00105631840.029
organophosphate catabolic processGO:00464342320.028
negative regulation of protein metabolic processGO:00512482820.028
membrane organizationGO:00610242450.028
ribonucleotide metabolic processGO:00092592910.028
purine nucleotide metabolic processGO:00061633020.028
mitochondrion organizationGO:00070051340.028
purine ribonucleotide metabolic processGO:00091502900.027
acyl coa metabolic processGO:0006637190.027
small gtpase mediated signal transductionGO:0007264970.027
organic cyclic compound catabolic processGO:19013612950.027
negative regulation of molecular functionGO:00440922580.027
small molecule catabolic processGO:0044282710.027
organic anion transportGO:00157111370.026
regulation of transferase activityGO:00513382630.026
generation of precursor metabolites and energyGO:00060911030.026
lipid modificationGO:0030258650.026
thioester metabolic processGO:0035383190.026
organic acid biosynthetic processGO:0016053860.026
proteolysis involved in cellular protein catabolic processGO:00516031470.026
cellular macromolecule catabolic processGO:00442652060.025
cytoplasmic transportGO:00164822340.025
fatty acid biosynthetic processGO:0006633410.025
heterocycle catabolic processGO:00467002800.025
response to organic cyclic compoundGO:00140701980.025
cellular response to organonitrogen compoundGO:00714171450.025
regulation of protein kinase activityGO:00458592320.025
acylglycerol metabolic processGO:0006639550.025
intracellular protein transportGO:00068862040.024
negative regulation of cellular protein metabolic processGO:00322692470.024
response to organonitrogen compoundGO:00102432460.024
maintenance of locationGO:0051235890.024
nitrogen compound transportGO:00717052710.024
lipid localizationGO:00108761260.023
aromatic compound catabolic processGO:00194392860.023
cellular protein catabolic processGO:00442571550.023
regulation of hormone levelsGO:00108172110.023
regulation of protein localizationGO:00328802310.023
coenzyme biosynthetic processGO:0009108230.023
organelle fissionGO:00482851700.023
mapk cascadeGO:00001652810.023
regulation of cellular response to stressGO:00801351590.023
ribonucleoside metabolic processGO:00091192450.022
cellular modified amino acid metabolic processGO:0006575630.022
regulation of mapk cascadeGO:00434082480.022
cellular homeostasisGO:00197252400.022
negative regulation of phosphorylationGO:00423261660.022
cation transportGO:00068123990.022
organic acid transportGO:00158491010.022
apoptotic signaling pathwayGO:00971903060.022
regulation of organelle organizationGO:00330432890.022
nucleoside phosphate catabolic processGO:19012922220.022
nucleotide catabolic processGO:00091662170.022
purine ribonucleoside triphosphate metabolic processGO:00092052200.022
phospholipid metabolic processGO:0006644870.021
peptidyl amino acid modificationGO:00181933360.021
regulation of cell activationGO:00508652890.021
ribonucleoside triphosphate metabolic processGO:00091992200.021
regulation of lipid metabolic processGO:00192161180.021
purine nucleoside metabolic processGO:00422782410.021
organophosphate biosynthetic processGO:00904071220.021
sterol metabolic processGO:0016125580.020
cell adhesionGO:00071553290.020
glycosyl compound metabolic processGO:19016572460.020
purine nucleotide catabolic processGO:00061952110.020
peptide metabolic processGO:0006518460.020
cellular nitrogen compound catabolic processGO:00442702800.020
organic acid catabolic processGO:0016054510.020
triglyceride metabolic processGO:0006641510.020
inflammatory responseGO:00069542440.020
dna metabolic processGO:00062593030.020
negative regulation of protein phosphorylationGO:00019331260.019
regulation of homeostatic processGO:00328441820.019
cellular response to hormone stimulusGO:00328701500.019
pyruvate metabolic processGO:0006090280.019
cell type specific apoptotic processGO:00972852680.019
negative regulation of transferase activityGO:0051348850.019
positive regulation of apoptotic processGO:00430652170.019
negative regulation of phosphate metabolic processGO:00459361840.019
cellular biogenic amine metabolic processGO:0006576280.019
regulation of lymphocyte activationGO:00512492400.019
carbohydrate derivative biosynthetic processGO:19011371830.019
regulation of kinase activityGO:00435492490.019
reactive oxygen species metabolic processGO:0072593840.019
leukocyte differentiationGO:00025213420.019
modification dependent macromolecule catabolic processGO:00436321330.018
negative regulation of protein modification processGO:00314001630.018
positive regulation of programmed cell deathGO:00430682180.018
negative regulation of intracellular signal transductionGO:19025321670.018
actin cytoskeleton organizationGO:00300362200.018
homeostasis of number of cellsGO:00488722100.018
positive regulation of cell deathGO:00109422240.018
lipid catabolic processGO:0016042690.018
long chain fatty acid importGO:004453920.018
purine containing compound catabolic processGO:00725232130.018
anion transmembrane transportGO:0098656710.018
protein modification by small protein conjugationGO:00324461870.018
regulation of mitochondrial fissionGO:009014030.018
response to radiationGO:00093141650.017
protein localization to organelleGO:00333651850.017
cation transmembrane transportGO:00986552660.017
cellular amide metabolic processGO:0043603580.017
cellular chemical homeostasisGO:00550822150.017
purine ribonucleotide catabolic processGO:00091542080.017
germ cell developmentGO:00072811850.017
negative regulation of kinase activityGO:0033673810.017
regulation of response to woundingGO:19030341890.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
microtubule based processGO:00070172360.017
positive regulation of protein modification processGO:00314012990.017
protein processingGO:00164851630.017
glycerophospholipid metabolic processGO:0006650710.017
inorganic ion transmembrane transportGO:00986602340.017
positive regulation of cellular catabolic processGO:00313311480.017
regulation of defense responseGO:00313472330.016
regulation of protein serine threonine kinase activityGO:00719001570.016
response to acid chemicalGO:00011011110.016
glutathione metabolic processGO:0006749160.016
negative regulation of cellular component organizationGO:00511291940.016
regulation of neuron differentiationGO:00456642810.016
forebrain developmentGO:00309003020.016
cellular lipid catabolic processGO:0044242520.016
rho protein signal transductionGO:0007266320.016
cellular response to cytokine stimulusGO:00713451890.016
response to lipopolysaccharideGO:00324961280.016
purine nucleoside catabolic processGO:00061522050.016
immune effector processGO:00022523210.016
endomembrane system organizationGO:00102561470.016
cellular response to acid chemicalGO:0071229680.016
inorganic cation transmembrane transportGO:00986622070.016
striated muscle tissue developmentGO:00147062930.016
reactive nitrogen species metabolic processGO:200105700.016
muscle cell differentiationGO:00426922610.016
regulation of cytokine productionGO:00018172660.016
carboxylic acid transportGO:00469421000.015
spermatid differentiationGO:00485151150.015
lipid transportGO:0006869980.015
neuronal action potentialGO:0019228540.015
myeloid cell differentiationGO:00300992330.015
multicellular organismal homeostasisGO:00488711640.015
transmission of nerve impulseGO:0019226760.015
response to molecule of bacterial originGO:00022371430.015
protein ubiquitinationGO:00165671710.015
regulation of anatomical structure sizeGO:00900661780.015
cellular carbohydrate metabolic processGO:00442621190.015
cytokine productionGO:00018163190.015
lipid homeostasisGO:0055088630.015
modification dependent protein catabolic processGO:00199411330.015
regulation of cell migrationGO:00303342190.015
meiotic cell cycleGO:00513211220.015
nucleocytoplasmic transportGO:00069131390.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
regulation of cell motilityGO:20001452360.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of intracellular transportGO:00323861590.015
sensory perceptionGO:00076002450.015
carbohydrate biosynthetic processGO:0016051740.015
carbohydrate derivative catabolic processGO:19011362310.015
cellular response to lipidGO:00713961450.015
regulation of secretionGO:00510462740.015
defense response to other organismGO:00985421970.015
cofactor biosynthetic processGO:0051188410.015
glucose homeostasisGO:00425931280.014
metal ion homeostasisGO:00550651890.014
fat cell differentiationGO:00454441600.014
purine ribonucleoside catabolic processGO:00461302050.014
negative regulation of cell proliferationGO:00082852960.014
regulation of t cell activationGO:00508631700.014
ubiquitin dependent protein catabolic processGO:00065111290.014
regulation of purine nucleotide metabolic processGO:19005421690.014
regulation of cellular component biogenesisGO:00440871810.014
response to growth factorGO:00708481980.014
muscle tissue developmentGO:00605373080.014
amide transportGO:00428861380.014
cellular alcohol metabolic processGO:004410730.014
cholesterol metabolic processGO:0008203560.014
positive regulation of glycolytic processGO:004582140.014
protein maturationGO:00516041760.014
intracellular mrna localizationGO:000829840.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
multicellular organismal signalingGO:0035637910.014
regulation of vesicle mediated transportGO:00606271390.014
cytokine mediated signaling pathwayGO:00192211150.014
acylglycerol biosynthetic processGO:0046463180.014
regulation of multi organism processGO:00439001110.014
ribonucleotide catabolic processGO:00092612080.014
ossificationGO:00015032160.014
regulation of apoptotic signaling pathwayGO:20012331970.013
steroid metabolic processGO:00082021190.013
energy derivation by oxidation of organic compoundsGO:0015980770.013
regulation of hydrolase activityGO:00513362460.013
locomotory behaviorGO:00076261950.013
regulation of purine nucleotide catabolic processGO:00331211220.013
monosaccharide metabolic processGO:00059961060.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
response to inorganic substanceGO:0010035960.013
response to extracellular stimulusGO:00099911270.013
regulation of leukocyte differentiationGO:19021051590.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
regulation of cellular component sizeGO:00325351210.013
cellular response to biotic stimulusGO:0071216920.013
regulation of cell projection organizationGO:00313442060.013
regulation of nucleotide catabolic processGO:00308111220.013
nucleoside triphosphate metabolic processGO:00091412300.013
acetate metabolic processGO:000608310.013
blood vessel morphogenesisGO:00485142850.013
cellular response to dna damage stimulusGO:00069742070.013
positive regulation of nervous system developmentGO:00519622210.013
lateral inhibitionGO:004633110.013
negative regulation of immune system processGO:00026832090.013
glycosyl compound catabolic processGO:19016582060.013
nucleoside triphosphate catabolic processGO:00091432050.013
cation homeostasisGO:00550802120.013
cellular response to growth factor stimulusGO:00713631970.013
regulation of establishment of protein localizationGO:00702011810.013
mitotic cell cycleGO:00002781950.012
glycoprotein metabolic processGO:00091001160.012
peptide transportGO:00158331330.012
regulation of map kinase activityGO:00434051200.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
skeletal system developmentGO:00015013560.012
spermatid developmentGO:00072861080.012
skin developmentGO:00435882200.012
hormone secretionGO:00468791280.012
cellular response to lipopolysaccharideGO:0071222770.012
endocytosisGO:00068971680.012
multicellular organism growthGO:00352641610.012
carbohydrate homeostasisGO:00335001280.012
response to peptide hormoneGO:00434341270.012
cellular response to molecule of bacterial originGO:0071219830.012
monocarboxylic acid transportGO:0015718440.012
action potentialGO:0001508780.012
nucleoside catabolic processGO:00091642060.012
tissue homeostasisGO:00018941150.012
chromatin organizationGO:00063252060.012
adult behaviorGO:00305341350.012
response to peptideGO:19016521360.012
t cell activationGO:00421102890.012
regulation of secretion by cellGO:19035302490.012
guanosine containing compound metabolic processGO:19010681440.012
long chain fatty acid metabolic processGO:0001676260.012
ribonucleoside catabolic processGO:00424542060.012
negative regulation of cellular amine metabolic processGO:003323910.012
innate immune responseGO:00450871570.012
leukocyte proliferationGO:00706611720.012
lymphocyte differentiationGO:00300982420.012
monocarboxylic acid catabolic processGO:0072329270.012
renal system developmentGO:00720012250.012
atp metabolic processGO:0046034750.012
sulfur compound biosynthetic processGO:0044272370.012
carboxylic acid catabolic processGO:0046395510.012
ribonucleoside triphosphate catabolic processGO:00092031990.011
anatomical structure homeostasisGO:00602491450.011
epithelial cell developmentGO:00020641590.011
leukocyte migrationGO:00509001240.011
nuclear divisionGO:00002801580.011
peptide secretionGO:00027901140.011
response to drugGO:0042493750.011
mrna metabolic processGO:0016071840.011
protein targetingGO:00066051430.011
nucleoside monophosphate metabolic processGO:0009123850.011
regulation of transmembrane transportGO:00347621280.011
hexose metabolic processGO:0019318980.011
cellular protein complex assemblyGO:00436231160.011
respiratory system developmentGO:00605411900.011
sequestering of calcium ionGO:0051208180.011
angiogenesisGO:00015252010.011
blood circulationGO:00080151950.011
proteasomal protein catabolic processGO:0010498980.011
glycerophospholipid biosynthetic processGO:0046474320.011
microtubule cytoskeleton organizationGO:00002261570.011
positive regulation of reactive oxygen species metabolic processGO:2000379110.011
circulatory system processGO:00030131970.011
gland developmentGO:00487323300.011
regulation of protein catabolic processGO:00421761080.011
positive regulation of cell developmentGO:00107202370.011
camera type eye developmentGO:00430102660.011
regulation of cell adhesionGO:00301551540.011
g protein coupled receptor signaling pathwayGO:00071862430.011
nucleoside phosphate biosynthetic processGO:1901293790.011
neuron deathGO:00709971540.011
plasma membrane organizationGO:0007009900.011
developmental maturationGO:00217001930.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.011
glucose metabolic processGO:0006006920.011
nuclear transportGO:00511691390.011
establishment of protein localization to organelleGO:00725941180.011
synaptic transmissionGO:00072683290.011
rna processingGO:00063961050.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
protein localization to membraneGO:00726571080.011
methylationGO:00322591340.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.011
mitochondrial transportGO:0006839360.011
response to nutrient levelsGO:00316671090.011
response to epidermal growth factorGO:007084940.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
nucleotide biosynthetic processGO:0009165780.010
protein glycosylationGO:0006486550.010
cellularizationGO:000734910.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
cellular component assembly involved in morphogenesisGO:00109271390.010
regulation of system processGO:00440572000.010
response to light stimulusGO:00094161350.010
interspecies interaction between organismsGO:0044419830.010
oocyte axis specificationGO:000730920.010
peptide hormone secretionGO:00300721090.010
regulation of endocytosisGO:0030100690.010
translationGO:0006412930.010
peptidyl tyrosine modificationGO:00182121450.010
fatty acid transmembrane transportGO:190200110.010
meiotic nuclear divisionGO:00071261150.010
dephosphorylationGO:00163111290.010
regulation of lymphocyte differentiationGO:00456191070.010
cellular ion homeostasisGO:00068731650.010
epithelial cell proliferationGO:00506731740.010
divalent metal ion transportGO:00708381720.010
organic hydroxy compound biosynthetic processGO:1901617770.010
regulation of proteolysisGO:00301621640.010

Me1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.037
inherited metabolic disorderDOID:65500.024
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.021
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
musculoskeletal system diseaseDOID:1700.015
central nervous system diseaseDOID:33100.013
neuropathyDOID:87000.012
muscular diseaseDOID:008000000.010
muscle tissue diseaseDOID:6600.010
connective tissue diseaseDOID:6500.010
organ system cancerDOID:005068600.010