Mus musculus

2 known processes

Asah1

N-acylsphingosine amidohydrolase 1

(Aliases: 2310081N20Rik,AC,Asah)

Asah1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ceramide metabolic processGO:0006672310.393
sphingolipid biosynthetic processGO:0030148260.227
positive regulation of neutrophil apoptotic processGO:003303110.224
sphingolipid catabolic processGO:003014970.218
regulation of angiotensin levels in bloodGO:000200240.200
vacuole organizationGO:0007033380.181
lysosome organizationGO:0007040210.167
non canonical wnt signaling pathwayGO:0035567330.160
regulation of angiotensin metabolic processGO:006017740.159
protein processingGO:00164851630.157
ceramide biosynthetic processGO:0046513200.154
sphingosine metabolic processGO:000667040.143
carbohydrate derivative catabolic processGO:19011362310.139
leukocyte mediated immunityGO:00024431740.128
sphingolipid metabolic processGO:0006665450.126
cytokine productionGO:00018163190.122
action potentialGO:0001508780.118
negative regulation of calcium ion dependent exocytosisGO:004595530.117
retrograde transport endosome to golgiGO:004214720.111
peptide metabolic processGO:0006518460.108
vesicle organizationGO:0016050600.107
immune effector processGO:00022523210.106
fibrinolysisGO:004273030.106
membrane lipid biosynthetic processGO:0046467320.104
organelle assemblyGO:00709251770.095
lytic vacuole organizationGO:0080171210.088
positive regulation of mapk cascadeGO:00434101700.087
regulation of mapk cascadeGO:00434082480.086
adaptive immune responseGO:00022501550.085
positive regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030910.082
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.079
establishment of planar polarityGO:0001736280.078
nucleoside phosphate metabolic processGO:00067533380.077
membrane lipid metabolic processGO:0006643530.077
amine metabolic processGO:0009308450.074
acid secretionGO:0046717330.073
positive regulation of membrane protein ectodomain proteolysisGO:005104430.072
organonitrogen compound catabolic processGO:19015652640.069
regulation of exocytosisGO:0017157610.069
icosanoid secretionGO:0032309120.069
regulation of interleukin 8 secretionGO:200048220.067
wnt signaling pathway planar cell polarity pathwayGO:0060071270.066
prevention of polyspermyGO:006046840.065
organophosphate catabolic processGO:00464342320.064
carboxylic acid transportGO:00469421000.063
nucleoside triphosphate metabolic processGO:00091412300.063
cellular amino acid metabolic processGO:00065201030.063
cellular lipid metabolic processGO:00442553230.062
metal ion homeostasisGO:00550651890.061
cellular homeostasisGO:00197252400.061
regulation of secretion by cellGO:19035302490.061
extracellular matrix dependent thymocyte migrationGO:007268010.061
regulation of neutrophil apoptotic processGO:003302910.059
myelinationGO:0042552740.059
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.058
regulation of muscle contractionGO:0006937490.057
organic acid transportGO:00158491010.057
regulation of membrane potentialGO:00423911920.057
macromolecule catabolic processGO:00090572810.056
lipid transportGO:0006869980.056
wnt signaling pathwayGO:00160551880.056
regulation of protein transportGO:00512231630.054
neutrophil apoptotic processGO:000178130.054
leukocyte apoptotic processGO:0071887710.053
nucleobase containing small molecule metabolic processGO:00550863520.053
membrane protein proteolysisGO:0033619100.052
exosomal secretionGO:199018210.051
regulation of protein localizationGO:00328802310.050
mapk cascadeGO:00001652810.049
negative regulation of protein transportGO:0051224460.049
calcium ion homeostasisGO:00550741270.048
regulation of muscle system processGO:0090257800.047
regulation of thymocyte migrationGO:200041020.047
apoptotic signaling pathwayGO:00971903060.046
transmission of nerve impulseGO:0019226760.046
positive regulation of eosinophil migrationGO:200041820.045
phagolysosome assemblyGO:000184530.045
sphingoid metabolic processGO:004651950.045
positive regulation of protein phosphorylationGO:00019342420.045
regulation of cytokine productionGO:00018172660.043
cellular divalent inorganic cation homeostasisGO:00725031270.043
cellular amine metabolic processGO:0044106440.042
fatty acid derivative transportGO:1901571140.042
lipid biosynthetic processGO:00086101790.042
cytoplasmic transportGO:00164822340.041
purine ribonucleotide catabolic processGO:00091542080.041
thymocyte migrationGO:007267920.041
pigmentationGO:0043473710.041
regulation of secretionGO:00510462740.040
cellular nitrogen compound catabolic processGO:00442702800.040
transmembrane transportGO:00550854120.040
coagulationGO:0050817780.040
protein catabolic processGO:00301632210.040
anion transportGO:00068201770.039
positive regulation of protein modification processGO:00314012990.039
regulation of cellular amino acid metabolic processGO:000652150.039
purine nucleoside metabolic processGO:00422782410.039
defense response to bacteriumGO:00427421190.038
positive regulation of myeloid cell apoptotic processGO:003303440.038
neurotransmitter secretionGO:0007269620.038
positive regulation of exocytosisGO:0045921200.038
multicellular organismal signalingGO:0035637910.037
bone resorptionGO:0045453380.037
substrate dependent cell migration cell extensionGO:000693040.037
hemostasisGO:0007599780.037
rap protein signal transductionGO:003248630.036
cation transportGO:00068123990.036
protein maturationGO:00516041760.036
cell adhesionGO:00071553290.036
interleukin 8 secretionGO:007260630.036
purine nucleoside catabolic processGO:00061522050.036
cellular ion homeostasisGO:00068731650.036
muscle contractionGO:00069361010.036
blood vessel morphogenesisGO:00485142850.035
leukocyte mediated cytotoxicityGO:0001909620.035
inflammatory responseGO:00069542440.034
neural tube developmentGO:00219151600.034
long chain fatty acid transportGO:0015909150.034
transforming growth factor beta1 productionGO:003290530.033
purine ribonucleoside triphosphate metabolic processGO:00092052200.033
cellular response to thyroid hormone stimulusGO:009706710.033
regulation of transferase activityGO:00513382630.033
epidermis developmentGO:00085441870.033
organic anion transportGO:00157111370.032
establishment of vesicle localizationGO:0051650810.032
negative regulation of interleukin 8 secretionGO:200048310.032
adult locomotory behaviorGO:0008344910.032
cation homeostasisGO:00550802120.032
exocytosisGO:00068871210.032
aromatic compound catabolic processGO:00194392860.032
phagosome maturationGO:009038240.031
neuromuscular process controlling balanceGO:0050885590.031
cellular protein catabolic processGO:00442571550.031
positive regulation of wnt signaling pathwayGO:0030177450.031
angiogenesisGO:00015252010.030
positive regulation of cell adhesionGO:0045785800.030
positive regulation of homeostatic processGO:0032846640.030
glycolipid catabolic processGO:001937750.030
interleukin 1 alpha secretionGO:005070330.030
positive regulation of apoptotic processGO:00430652170.030
negative regulation of synaptic vesicle transportGO:190280430.030
regulation of establishment of protein localizationGO:00702011810.029
small gtpase mediated signal transductionGO:0007264970.029
fatty acid transportGO:0015908280.029
response to osmotic stressGO:0006970210.029
intracellular protein transportGO:00068862040.029
purine ribonucleoside metabolic processGO:00461282410.029
cellular macromolecule catabolic processGO:00442652060.028
regulation of homeostatic processGO:00328441820.028
membrane organizationGO:00610242450.028
cellular water homeostasisGO:000999220.028
activation of mapk activityGO:0000187590.028
circulatory system processGO:00030131970.028
positive regulation of cell deathGO:00109422240.028
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.028
regulation of response to woundingGO:19030341890.027
wound healingGO:00420601570.027
neuronal action potentialGO:0019228540.027
hepaticobiliary system developmentGO:0061008670.027
regulation of wnt signaling pathwayGO:00301111230.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.027
maintenance of locationGO:0051235890.027
regulation of system processGO:00440572000.027
activation of mapk activity involved in innate immune responseGO:003541920.026
monocarboxylic acid transportGO:0015718440.026
regulation of vesicle mediated transportGO:00606271390.026
cellular calcium ion homeostasisGO:00068741190.026
tumor necrosis factor ligand superfamily member 11 productionGO:007253510.026
cellular amide metabolic processGO:0043603580.026
vacuolar transportGO:0007034110.026
intrahepatic bile duct developmentGO:003562220.026
positive regulation of hydrolase activityGO:00513451480.025
multi multicellular organism processGO:00447061090.025
heterocycle catabolic processGO:00467002800.025
glycosphingolipid catabolic processGO:004647950.025
regulation of cellular ketone metabolic processGO:0010565660.025
ion transmembrane transportGO:00342203610.025
establishment of protein localization to vacuoleGO:007266640.025
cellular metal ion homeostasisGO:00068751510.025
regulation of cellular response to growth factor stimulusGO:0090287820.025
myeloid cell apoptotic processGO:0033028220.025
locomotory behaviorGO:00076261950.025
hormone metabolic processGO:0042445860.024
eosinophil migrationGO:007267730.024
adult behaviorGO:00305341350.024
regulation of bone resorptionGO:0045124240.024
leukocyte homeostasisGO:0001776790.024
regulation of cellular catabolic processGO:00313292420.024
protein localization to vacuoleGO:007266540.024
cellular chemical homeostasisGO:00550822150.024
small molecule biosynthetic processGO:00442831320.024
regulation of fibronectin dependent thymocyte migrationGO:200041310.024
protein localization involved in establishment of planar polarityGO:009025110.024
tissue homeostasisGO:00018941150.024
astrocyte cell migrationGO:004361530.024
pma inducible membrane protein ectodomain proteolysisGO:005108810.023
skin developmentGO:00435882200.023
myeloid leukocyte activationGO:0002274830.023
regulation of neuron projection developmentGO:00109751690.022
nucleotide catabolic processGO:00091662170.022
glycosyl compound catabolic processGO:19016582060.022
pigment granule localizationGO:0051875130.022
bone remodelingGO:0046849530.022
regulation of vascular smooth muscle contractionGO:000305610.022
regulation of protein maturationGO:1903317960.022
morphogenesis of a polarized epitheliumGO:0001738370.022
phospholipid metabolic processGO:0006644870.022
cell type specific apoptotic processGO:00972852680.022
negative regulation of molecular functionGO:00440922580.022
stem cell maintenanceGO:00198271300.021
regulation of kinase activityGO:00435492490.021
positive regulation of cytokine productionGO:00018191740.021
eye pigmentationGO:004806930.021
g1 s transition of mitotic cell cycleGO:0000082570.021
acute inflammatory responseGO:0002526410.021
positive regulation of thymocyte migrationGO:200041220.021
axon ensheathmentGO:0008366760.021
regulation of intracellular transportGO:00323861590.021
multi organism reproductive behaviorGO:0044705290.021
lipid localizationGO:00108761260.021
regulation of map kinase activityGO:00434051200.021
regulation of cellular amine metabolic processGO:0033238200.020
establishment of tissue polarityGO:0007164280.020
nuclear importGO:0051170950.020
protein autoprocessingGO:001654020.020
regulation of organelle organizationGO:00330432890.020
cell chemotaxisGO:0060326810.020
regulation of blood pressureGO:0008217930.020
positive regulation of immune effector processGO:00026991070.019
positive regulation of cell cycle g1 s phase transitionGO:190280890.019
male courtship behaviorGO:000804920.019
ensheathment of neuronsGO:0007272760.019
calcium ion dependent exocytosisGO:0017156350.019
gliogenesisGO:00420631410.019
receptor localization to synapseGO:009712040.019
regulation of hormone levelsGO:00108172110.019
divalent inorganic cation transportGO:00725111780.019
organonitrogen compound biosynthetic processGO:19015661920.019
nucleotide metabolic processGO:00091173320.019
regulation of myeloid cell apoptotic processGO:0033032190.019
protein complex disassemblyGO:0043241400.019
membrane lipid catabolic processGO:004646680.019
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:0001991130.019
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.018
calcium ion transportGO:00068161590.018
positive regulation of kinase activityGO:00336741550.018
homeostasis of number of cellsGO:00488722100.018
nucleoside metabolic processGO:00091162460.018
leukocyte differentiationGO:00025213420.018
endocytosisGO:00068971680.018
regulation of cell motilityGO:20001452360.018
positive regulation of transforming growth factor beta1 productionGO:003291420.018
cell killingGO:0001906670.018
protein targeting to vacuoleGO:000662330.018
regulation of apoptotic signaling pathwayGO:20012331970.018
lymphocyte mediated immunityGO:00024491390.018
neuromuscular processGO:0050905990.018
positive regulation of t cell mediated cytotoxicityGO:0001916150.018
anatomical structure homeostasisGO:00602491450.018
regulation of leukocyte apoptotic processGO:2000106560.018
ribonucleoside metabolic processGO:00091192450.017
regulation of tissue remodelingGO:0034103380.017
endodermal cell fate specificationGO:000171440.017
positive regulation of protein kinase activityGO:00458601440.017
epithelial cell proliferationGO:00506731740.017
organelle localizationGO:00516401790.017
tissue remodelingGO:00487711020.017
protein importGO:00170381010.017
regulation of neurotransmitter levelsGO:0001505870.017
purine ribonucleoside catabolic processGO:00461302050.017
regulation of cytoplasmic transportGO:19036491120.017
regulation of proteolysisGO:00301621640.017
glycosaminoglycan metabolic processGO:0030203340.017
icosanoid transportGO:0071715140.017
divalent metal ion transportGO:00708381720.017
ribonucleoside catabolic processGO:00424542060.017
transforming growth factor beta receptor signaling pathwayGO:0007179710.017
positive regulation of mitotic cell cycleGO:0045931410.017
positive regulation of cellular amine metabolic processGO:003324050.016
regulation of protein catabolic processGO:00421761080.016
regulation of leukocyte mediated cytotoxicityGO:0001910380.016
membrane fusionGO:0061025380.016
nucleoside catabolic processGO:00091642060.016
positive regulation of secretion by cellGO:19035321140.016
carboxylic acid biosynthetic processGO:0046394860.016
cellular response to transforming growth factor beta stimulusGO:0071560880.016
stem cell developmentGO:00488642190.016
purine containing compound metabolic processGO:00725213110.016
cellular protein complex assemblyGO:00436231160.016
organic hydroxy compound metabolic processGO:19016152030.016
posttranscriptional regulation of gene expressionGO:00106081550.015
blood circulationGO:00080151950.015
regulation of calcium ion dependent exocytosisGO:0017158160.015
glycolipid metabolic processGO:0006664250.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
regulation of peptidase activityGO:0052547960.015
diol metabolic processGO:003431150.015
positive regulation of g1 s transition of mitotic cell cycleGO:190008790.015
cell recognitionGO:0008037830.015
ribose phosphate metabolic processGO:00196932910.015
negative regulation of protein metabolic processGO:00512482820.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
regulation of reproductive processGO:2000241660.014
protein targetingGO:00066051430.014
response to inorganic substanceGO:0010035960.014
establishment of organelle localizationGO:00516561220.014
ceramide catabolic processGO:004651470.014
engulfment of apoptotic cellGO:004365230.014
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.014
regulation of protein kinase activityGO:00458592320.014
membrane protein ectodomain proteolysisGO:000650970.014
regulation of protein serine threonine kinase activityGO:00719001570.014
glial cell differentiationGO:00100011310.014
regulation of interleukin 8 productionGO:003267730.014
regulation of protein processingGO:0070613960.014
vesicle fusionGO:0006906160.014
sterol transportGO:0015918380.014
positive regulation of cell cycle processGO:0090068610.014
negative regulation of calcium ion transmembrane transporter activityGO:190102010.014
cholesterol metabolic processGO:0008203560.014
positive regulation of cellular catabolic processGO:00313311480.014
keratinocyte migrationGO:005154630.014
peptidyl amino acid modificationGO:00181933360.014
t cell mediated cytotoxicityGO:0001913260.014
regulation of membrane protein ectodomain proteolysisGO:005104330.014
learningGO:0007612980.014
purine nucleotide metabolic processGO:00061633020.014
extracellular matrix organizationGO:00301981470.014
muscle system processGO:00030121410.013
regulation of protein stabilityGO:0031647520.013
positive regulation of interleukin 1 alpha productionGO:003273040.013
germinal center formationGO:0002467160.013
synaptic vesicle transportGO:0048489570.013
extracellular structure organizationGO:00430621480.013
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574330.013
regulation of interleukin 1 alpha productionGO:003265040.013
cation transmembrane transportGO:00986552660.013
alpha beta t cell activationGO:0046631910.013
amide transportGO:00428861380.013
response to acid chemicalGO:00011011110.013
stem cell differentiationGO:00488632680.013
nucleoside phosphate catabolic processGO:19012922220.013
glycosyl compound metabolic processGO:19016572460.013
regulation of hemostasisGO:1900046280.013
regulation of cell cycleGO:00517262810.013
establishment of synaptic vesicle localizationGO:0097480570.013
regulation of cell adhesionGO:00301551540.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
immune response regulating signaling pathwayGO:00027641250.013
regulation of cell shapeGO:0008360390.013
single fertilizationGO:0007338820.013
regulation of cell cycle g1 s phase transitionGO:1902806350.013
germ cell developmentGO:00072811850.013
cholesterol effluxGO:0033344240.013
oligosaccharide metabolic processGO:0009311110.013
positive regulation of leukocyte apoptotic processGO:2000108210.012
regulation of organ morphogenesisGO:20000271440.012
response to growth factorGO:00708481980.012
inorganic ion transmembrane transportGO:00986602340.012
t cell mediated immunityGO:0002456500.012
myeloid cell homeostasisGO:00022621140.012
regulation of hydrolase activityGO:00513362460.012
central nervous system morphogenesisGO:002155120.012
inorganic cation transmembrane transportGO:00986622070.012
amino acid transportGO:0006865610.012
response to thyroid hormoneGO:009706620.012
response to endoplasmic reticulum stressGO:0034976530.012
response to oxidative stressGO:00069791230.012
peptide hormone processingGO:001648690.012
melanosome transportGO:0032402110.012
positive regulation of protein autophosphorylationGO:003195440.012
negative regulation of neuron deathGO:1901215980.012
skeletal system developmentGO:00015013560.012
liposaccharide metabolic processGO:1903509270.012
protein localization to organelleGO:00333651850.012
cellular response to lipidGO:00713961450.012
cell activation involved in immune responseGO:00022631260.012
negative regulation of protein maturationGO:1903318790.012
organic hydroxy compound transportGO:0015850930.012
organelle fusionGO:0048284280.011
negative regulation of interleukin 8 productionGO:003271710.011
single organism cell adhesionGO:00986021560.011
endocrine processGO:0050886390.011
regulation of lymphocyte activationGO:00512492400.011
regulation of cell killingGO:0031341400.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
sensory perceptionGO:00076002450.011
epithelium migrationGO:0090132630.011
positive regulation of dna templated transcription elongationGO:003278620.011
cell cycle g1 s phase transitionGO:0044843570.011
sequestering of metal ionGO:0051238190.011
lysosomal transportGO:0007041100.011
ribonucleotide metabolic processGO:00092592910.011
regulation of neuron apoptotic processGO:00435231220.011
divalent inorganic cation homeostasisGO:00725071380.011
male gamete generationGO:00482322850.011
regulation of lymphocyte mediated immunityGO:0002706840.011
negative regulation of synaptic vesicle exocytosisGO:200030130.011
negative regulation of cytokine productionGO:0001818840.011
response to organic cyclic compoundGO:00140701980.011
positive regulation of mitotic cell cycle phase transitionGO:1901992170.011
regulation of nucleocytoplasmic transportGO:0046822730.011
cofactor transportGO:005118140.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
response to reactive oxygen speciesGO:0000302560.011
positive regulation of t cell mediated immunityGO:0002711240.011
b cell activationGO:00421131610.011
cellular ketone metabolic processGO:0042180840.011
sterol metabolic processGO:0016125580.011
positive regulation of protein transportGO:0051222930.011
activation of mapkk activityGO:0000186150.011
cellular biogenic amine metabolic processGO:0006576280.011
regulation of t cell activationGO:00508631700.010
protein kinase b signalingGO:0043491740.010
purine nucleoside triphosphate metabolic processGO:00091442260.010
neural tube patterningGO:0021532430.010
cell cell adhesionGO:0098609410.010
guanosine containing compound metabolic processGO:19010681440.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
neutrophil homeostasisGO:000178070.010
regulation of eosinophil migrationGO:200041620.010
negative regulation of calcium ion transmembrane transportGO:190317010.010
positive regulation of transferase activityGO:00513471670.010
phosphatidylethanolamine biosynthetic processGO:000664620.010
liver developmentGO:0001889660.010
regulation of mitotic cell cycle phase transitionGO:1901990730.010
myeloid leukocyte migrationGO:0097529570.010
regulation of systemic arterial blood pressure by hormoneGO:0001990250.010
response to nutrient levelsGO:00316671090.010
gland developmentGO:00487323300.010
interleukin 8 productionGO:003263740.010

Asah1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.852
Human
disease of metabolismDOID:001466700.852
Human
lysosomal storage diseaseDOID:321100.666
Human
nervous system diseaseDOID:86300.590
disease of anatomical entityDOID:700.590
central nervous system diseaseDOID:33100.265
lipid storage diseaseDOID:945500.226
Human
brain diseaseDOID:93600.218
sphingolipidosisDOID:192700.159
eye and adnexa diseaseDOID:149200.080
sensory system diseaseDOID:005015500.080
eye diseaseDOID:561400.080
retinal degenerationDOID:846600.074
retinal diseaseDOID:567900.074
neurodegenerative diseaseDOID:128900.030
electroclinical syndromeDOID:005070100.016
epilepsy syndromeDOID:182600.016
bone diseaseDOID:008000100.014
osteopetrosisDOID:1353300.014
bone remodeling diseaseDOID:008000500.014
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.014
osteosclerosisDOID:425400.014
disease of mental healthDOID:15000.014
cerebral degenerationDOID:144300.013
mouth diseaseDOID:40300.013
gastrointestinal system diseaseDOID:7700.013