| ion transmembrane transport | GO:0034220 | 361 | 0.207 | |
| transmembrane transport | GO:0055085 | 412 | 0.128 | |
| anion transport | GO:0006820 | 177 | 0.121 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.117 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.101 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.100 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.084 | Fly |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.082 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.077 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.068 | |
| antibacterial peptide biosynthetic process | GO:0002780 | 2 | 0.066 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.063 | |
| regulation of protein localization | GO:0032880 | 231 | 0.060 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.058 | |
| inorganic anion transport | GO:0015698 | 43 | 0.057 | |
| isoprenoid metabolic process | GO:0006720 | 29 | 0.053 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.051 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.050 | Fly |
| negative regulation of molecular function | GO:0044092 | 258 | 0.045 | |
| ensheathment of neurons | GO:0007272 | 76 | 0.044 | |
| cellularization | GO:0007349 | 1 | 0.043 | |
| skin development | GO:0043588 | 220 | 0.043 | Mouse Fly |
| cellular amide metabolic process | GO:0043603 | 58 | 0.040 | |
| potassium ion transmembrane transport | GO:0071805 | 43 | 0.039 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.039 | |
| response to acid chemical | GO:0001101 | 111 | 0.039 | |
| protein oligomerization | GO:0051259 | 67 | 0.038 | |
| cation transport | GO:0006812 | 399 | 0.038 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.038 | Fly |
| organic anion transport | GO:0015711 | 137 | 0.036 | |
| antimicrobial peptide biosynthetic process | GO:0002777 | 2 | 0.036 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.035 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.035 | |
| sensory perception of sound | GO:0007605 | 97 | 0.034 | Mouse Fly |
| metal ion homeostasis | GO:0055065 | 189 | 0.034 | |
| regulation of defense response to bacterium | GO:1900424 | 3 | 0.033 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.033 | |
| amino acid betaine transport | GO:0015838 | 3 | 0.033 | |
| monocarboxylic acid transport | GO:0015718 | 44 | 0.032 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.032 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.032 | Fly |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.032 | |
| peptide metabolic process | GO:0006518 | 46 | 0.032 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.032 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.032 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.031 | Fly |
| camera type eye development | GO:0043010 | 266 | 0.031 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.031 | Fly |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.030 | |
| anion transmembrane transport | GO:0098656 | 71 | 0.030 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.030 | |
| sperm individualization | GO:0007291 | 1 | 0.029 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.028 | |
| amine metabolic process | GO:0009308 | 45 | 0.027 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.027 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.027 | |
| lipid localization | GO:0010876 | 126 | 0.027 | |
| response to oxidative stress | GO:0006979 | 123 | 0.027 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.026 | Fly |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.026 | |
| spermatogenesis | GO:0007283 | 284 | 0.026 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.026 | |
| sodium ion transport | GO:0006814 | 73 | 0.025 | |
| response to metal ion | GO:0010038 | 47 | 0.025 | |
| antimicrobial peptide production | GO:0002775 | 2 | 0.025 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.025 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.025 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.025 | Fly |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.025 | |
| immune effector process | GO:0002252 | 321 | 0.025 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.025 | |
| negative regulation of sterol transport | GO:0032372 | 4 | 0.025 | |
| maintenance of location | GO:0051235 | 89 | 0.025 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.024 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.024 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.024 | |
| retinoid metabolic process | GO:0001523 | 24 | 0.024 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.024 | Fly |
| epidermis development | GO:0008544 | 187 | 0.024 | Mouse Fly |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.024 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.023 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.023 | Fly |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.023 | Fly |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.023 | Fly |
| organic acid transport | GO:0015849 | 101 | 0.023 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.023 | Fly |
| toxin transport | GO:1901998 | 38 | 0.022 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.022 | Fly |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.022 | Fly |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.022 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.021 | Fly |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.021 | Fly |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.021 | |
| regulation of antimicrobial humoral response | GO:0002759 | 3 | 0.021 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.021 | |
| protein glycosylation | GO:0006486 | 55 | 0.021 | |
| vitamin a metabolic process | GO:0006776 | 2 | 0.021 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.021 | Fly |
| regulation of mapk cascade | GO:0043408 | 248 | 0.021 | |
| regulation of protein transport | GO:0051223 | 163 | 0.020 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.020 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.019 | |
| urate transport | GO:0015747 | 1 | 0.019 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.019 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.019 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.019 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.019 | |
| regulation of antibacterial peptide production | GO:0002786 | 1 | 0.019 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.019 | Fly |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.019 | |
| cellular homeostasis | GO:0019725 | 240 | 0.019 | |
| neuronal action potential | GO:0019228 | 54 | 0.019 | |
| male gamete generation | GO:0048232 | 285 | 0.019 | |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.018 | |
| regulation of cell activation | GO:0050865 | 289 | 0.018 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.018 | Fly |
| heterocycle catabolic process | GO:0046700 | 280 | 0.018 | Fly |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.018 | Fly |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.018 | Fly |
| innate immune response | GO:0045087 | 157 | 0.017 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.017 | Fly |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.017 | |
| developmental maturation | GO:0021700 | 193 | 0.017 | |
| sensory perception | GO:0007600 | 245 | 0.017 | Mouse Fly |
| organophosphate catabolic process | GO:0046434 | 232 | 0.017 | Fly |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.017 | Fly |
| regulation of antimicrobial peptide production | GO:0002784 | 1 | 0.017 | |
| water transport | GO:0006833 | 12 | 0.017 | |
| positive regulation of antibacterial peptide biosynthetic process | GO:0006963 | 1 | 0.017 | |
| leukocyte migration | GO:0050900 | 124 | 0.017 | |
| response to inorganic substance | GO:0010035 | 96 | 0.017 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.017 | Fly |
| transmission of nerve impulse | GO:0019226 | 76 | 0.017 | |
| regulation of ion transport | GO:0043269 | 215 | 0.016 | |
| positive regulation of homeostatic process | GO:0032846 | 64 | 0.016 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.016 | Fly |
| dephosphorylation | GO:0016311 | 129 | 0.016 | |
| regulation of antimicrobial peptide biosynthetic process | GO:0002805 | 1 | 0.016 | |
| response to peptide | GO:1901652 | 136 | 0.016 | |
| response to drug | GO:0042493 | 75 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.016 | Fly |
| lipid biosynthetic process | GO:0008610 | 179 | 0.016 | |
| digestion | GO:0007586 | 40 | 0.016 | |
| protein localization to membrane | GO:0072657 | 108 | 0.016 | |
| response to peptide hormone | GO:0043434 | 127 | 0.016 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.016 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.016 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.016 | |
| hormone secretion | GO:0046879 | 128 | 0.015 | |
| alcohol biosynthetic process | GO:0046165 | 43 | 0.015 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.015 | |
| cgmp biosynthetic process | GO:0006182 | 13 | 0.015 | |
| positive regulation of antimicrobial humoral response | GO:0002760 | 2 | 0.015 | |
| histamine uptake | GO:0051615 | 1 | 0.015 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 57 | 0.015 | Fly |
| amide transport | GO:0042886 | 138 | 0.015 | |
| negative regulation of cholesterol transport | GO:0032375 | 4 | 0.015 | |
| organic acid catabolic process | GO:0016054 | 51 | 0.015 | |
| regulation of cellular ph reduction | GO:0032847 | 2 | 0.015 | |
| germ cell development | GO:0007281 | 185 | 0.015 | |
| urogenital system development | GO:0001655 | 261 | 0.015 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.015 | Fly |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.015 | |
| calcium ion transport | GO:0006816 | 159 | 0.015 | |
| organophosphate ester transport | GO:0015748 | 28 | 0.015 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 0.015 | |
| regulation of vitamin metabolic process | GO:0030656 | 3 | 0.015 | |
| cation homeostasis | GO:0055080 | 212 | 0.015 | |
| modified amino acid transport | GO:0072337 | 5 | 0.015 | |
| protein ubiquitination | GO:0016567 | 171 | 0.014 | |
| wound healing | GO:0042060 | 157 | 0.014 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.014 | |
| stem cell differentiation | GO:0048863 | 268 | 0.014 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.014 | Fly |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.014 | |
| transition metal ion homeostasis | GO:0055076 | 54 | 0.014 | |
| regulation of interleukin 1 alpha production | GO:0032650 | 4 | 0.014 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.014 | Fly |
| fat soluble vitamin biosynthetic process | GO:0042362 | 4 | 0.014 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.014 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.014 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.014 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.014 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.014 | |
| spinal cord oligodendrocyte cell fate specification | GO:0021530 | 3 | 0.014 | |
| placenta development | GO:0001890 | 140 | 0.014 | |
| lateral inhibition | GO:0046331 | 1 | 0.013 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.013 | |
| organelle localization | GO:0051640 | 179 | 0.013 | Mouse |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.013 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.013 | |
| sensory perception of mechanical stimulus | GO:0050954 | 107 | 0.013 | Mouse Fly |
| positive regulation of cellular ph reduction | GO:0032849 | 2 | 0.013 | |
| heart morphogenesis | GO:0003007 | 178 | 0.013 | |
| cgmp metabolic process | GO:0046068 | 20 | 0.013 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.013 | |
| phospholipid transport | GO:0015914 | 21 | 0.013 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.013 | Fly |
| amino acid transport | GO:0006865 | 61 | 0.013 | |
| lipid homeostasis | GO:0055088 | 63 | 0.013 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.013 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.013 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.013 | Fly |
| negative regulation of macrophage activation | GO:0043031 | 2 | 0.013 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.013 | Fly |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.013 | |
| appendage development | GO:0048736 | 166 | 0.013 | Fly |
| response to iron ion | GO:0010039 | 4 | 0.013 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.012 | |
| carnitine transport | GO:0015879 | 3 | 0.012 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.012 | |
| carboxylic acid catabolic process | GO:0046395 | 51 | 0.012 | |
| female gamete generation | GO:0007292 | 74 | 0.012 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.012 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.012 | |
| chloride transport | GO:0006821 | 32 | 0.012 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.012 | |
| endomembrane system organization | GO:0010256 | 147 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.012 | Fly |
| compound eye development | GO:0048749 | 1 | 0.012 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.012 | |
| amino acid betaine metabolic process | GO:0006577 | 7 | 0.012 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.012 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.012 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.012 | Fly |
| negative regulation of androgen receptor signaling pathway | GO:0060766 | 3 | 0.012 | |
| positive regulation of antimicrobial peptide biosynthetic process | GO:0002807 | 1 | 0.012 | |
| regulation of androgen receptor signaling pathway | GO:0060765 | 3 | 0.012 | |
| cell chemotaxis | GO:0060326 | 81 | 0.012 | |
| glycosylation | GO:0070085 | 62 | 0.012 | |
| response to thyroid hormone | GO:0097066 | 2 | 0.012 | |
| developmental growth involved in morphogenesis | GO:0060560 | 138 | 0.012 | |
| regulation of inward rectifier potassium channel activity | GO:1901979 | 1 | 0.012 | |
| negative regulation of keratinocyte differentiation | GO:0045617 | 4 | 0.011 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.011 | |
| response to radiation | GO:0009314 | 165 | 0.011 | |
| carnitine metabolic process | GO:0009437 | 7 | 0.011 | |
| positive regulation of interleukin 1 alpha production | GO:0032730 | 4 | 0.011 | |
| t cell activation | GO:0042110 | 289 | 0.011 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.011 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.011 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.011 | Fly |
| transition metal ion transport | GO:0000041 | 38 | 0.011 | |
| synaptic transmission | GO:0007268 | 329 | 0.011 | |
| membrane organization | GO:0061024 | 245 | 0.011 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.011 | |
| intracellular protein transport | GO:0006886 | 204 | 0.011 | Mouse |
| carnitine transmembrane transport | GO:1902603 | 3 | 0.011 | |
| regulation of cell migration | GO:0030334 | 219 | 0.011 | |
| cdc42 protein signal transduction | GO:0032488 | 0 | 0.011 | |
| fat cell differentiation | GO:0045444 | 160 | 0.011 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.011 | |
| angiogenesis | GO:0001525 | 201 | 0.011 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.011 | |
| negative regulation of cell migration | GO:0030336 | 59 | 0.011 | |
| calcium ion transmembrane transport | GO:0070588 | 85 | 0.011 | |
| peptide transport | GO:0015833 | 133 | 0.011 | |
| regulation of cell motility | GO:2000145 | 236 | 0.011 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.011 | |
| response to temperature stimulus | GO:0009266 | 55 | 0.011 | |
| negative regulation of epithelial cell proliferation | GO:0050680 | 64 | 0.011 | |
| terpenoid metabolic process | GO:0006721 | 25 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.011 | Fly |
| response to water | GO:0009415 | 1 | 0.011 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.011 | |
| methionine transport | GO:0015821 | 1 | 0.011 | |
| diterpenoid biosynthetic process | GO:0016102 | 7 | 0.010 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.010 | |
| renal sodium ion transport | GO:0003096 | 2 | 0.010 | |
| neuron death | GO:0070997 | 154 | 0.010 | |
| plasma membrane organization | GO:0007009 | 90 | 0.010 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.010 | |
| regulation of antibacterial peptide biosynthetic process | GO:0002808 | 1 | 0.010 | |
| ear development | GO:0043583 | 200 | 0.010 | Mouse |
| muscle tissue development | GO:0060537 | 308 | 0.010 | |
| epithelial cell development | GO:0002064 | 159 | 0.010 | Mouse |
| mitotic cytokinesis | GO:0000281 | 4 | 0.010 | |
| response to water deprivation | GO:0009414 | 1 | 0.010 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.010 | Fly |
| membrane lipid metabolic process | GO:0006643 | 53 | 0.010 | |
| regulation of fat cell differentiation | GO:0045598 | 81 | 0.010 | |
| mrna metabolic process | GO:0016071 | 84 | 0.010 | |
| lens development in camera type eye | GO:0002088 | 62 | 0.010 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.010 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.010 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.010 | Fly |
| positive regulation of atpase activity | GO:0032781 | 3 | 0.010 | |
