| extracellular matrix organization | GO:0030198 | 147 | 0.896 | Fly |
| extracellular structure organization | GO:0043062 | 148 | 0.784 | Fly |
| regulation of proteolysis | GO:0030162 | 164 | 0.496 | |
| wound healing | GO:0042060 | 157 | 0.475 | Rat |
| regulation of cell motility | GO:2000145 | 236 | 0.356 | Human |
| muscle tissue development | GO:0060537 | 308 | 0.310 | |
| response to acid chemical | GO:0001101 | 111 | 0.249 | Rat |
| protein hydroxylation | GO:0018126 | 4 | 0.235 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.235 | Rat |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.226 | |
| cell adhesion | GO:0007155 | 329 | 0.208 | |
| cerebral cortex development | GO:0021987 | 86 | 0.199 | |
| cell matrix adhesion | GO:0007160 | 68 | 0.196 | |
| negative regulation of toll signaling pathway | GO:0045751 | 1 | 0.183 | |
| chondrocyte development | GO:0002063 | 24 | 0.182 | |
| cell substrate adhesion | GO:0031589 | 130 | 0.166 | |
| skeletal system development | GO:0001501 | 356 | 0.160 | |
| regulation of cell substrate adhesion | GO:0010810 | 73 | 0.160 | |
| response to amino acid | GO:0043200 | 37 | 0.152 | |
| negative regulation of cell migration | GO:0030336 | 59 | 0.150 | |
| inner ear morphogenesis | GO:0042472 | 101 | 0.149 | Zebrafish |
| cardiac muscle tissue morphogenesis | GO:0055008 | 44 | 0.144 | |
| retinal blood vessel morphogenesis | GO:0061304 | 3 | 0.139 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.133 | Zebrafish |
| sensory organ morphogenesis | GO:0090596 | 242 | 0.127 | Zebrafish |
| transmission of nerve impulse | GO:0019226 | 76 | 0.122 | |
| forebrain development | GO:0030900 | 302 | 0.121 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.121 | Rat |
| proteoglycan metabolic process | GO:0006029 | 38 | 0.121 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.118 | |
| regulation of toll signaling pathway | GO:0008592 | 1 | 0.108 | |
| long chain fatty acid import | GO:0044539 | 2 | 0.106 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.102 | |
| regulation of phospholipid biosynthetic process | GO:0071071 | 3 | 0.099 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.098 | Human |
| connective tissue development | GO:0061448 | 179 | 0.093 | Zebrafish |
| extracellular fibril organization | GO:0043206 | 2 | 0.090 | |
| response to growth factor | GO:0070848 | 198 | 0.085 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.082 | |
| protein trimerization | GO:0070206 | 13 | 0.082 | |
| collagen fibril organization | GO:0030199 | 32 | 0.081 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.080 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.076 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.074 | |
| insulin processing | GO:0030070 | 2 | 0.073 | |
| neutrophil apoptotic process | GO:0001781 | 3 | 0.073 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.072 | |
| protein maturation | GO:0051604 | 176 | 0.067 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.065 | |
| chondrocyte differentiation | GO:0002062 | 72 | 0.065 | |
| cartilage development involved in endochondral bone morphogenesis | GO:0060351 | 24 | 0.062 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.062 | |
| regulation of neutrophil apoptotic process | GO:0033029 | 1 | 0.061 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.058 | |
| notochord development | GO:0030903 | 20 | 0.056 | |
| protein heterooligomerization | GO:0051291 | 14 | 0.055 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.054 | |
| oviduct development | GO:0060066 | 3 | 0.053 | |
| regulation of system process | GO:0044057 | 200 | 0.051 | |
| limb morphogenesis | GO:0035108 | 149 | 0.051 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.051 | |
| cellular modified amino acid metabolic process | GO:0006575 | 63 | 0.049 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.048 | |
| sensory perception | GO:0007600 | 245 | 0.048 | |
| regulation of cell migration | GO:0030334 | 219 | 0.047 | Human |
| cellular response to amino acid stimulus | GO:0071230 | 29 | 0.047 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.047 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.047 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.046 | |
| peptidyl proline hydroxylation | GO:0019511 | 3 | 0.045 | |
| neuron migration | GO:0001764 | 122 | 0.045 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.044 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.042 | |
| cardiac chamber development | GO:0003205 | 108 | 0.041 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.041 | |
| membrane raft assembly | GO:0001765 | 3 | 0.040 | |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001240 | 16 | 0.039 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.039 | |
| heart morphogenesis | GO:0003007 | 178 | 0.039 | |
| tissue homeostasis | GO:0001894 | 115 | 0.039 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.038 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.038 | |
| camera type eye development | GO:0043010 | 266 | 0.038 | |
| fibril organization | GO:0097435 | 2 | 0.037 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.036 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.036 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.036 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.036 | Rat |
| cellular response to acid chemical | GO:0071229 | 68 | 0.036 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.035 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.035 | |
| action potential | GO:0001508 | 78 | 0.034 | |
| protein oligomerization | GO:0051259 | 67 | 0.034 | |
| appendage development | GO:0048736 | 166 | 0.034 | |
| positive regulation of ras protein signal transduction | GO:0046579 | 13 | 0.033 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.033 | |
| fibrinolysis | GO:0042730 | 3 | 0.033 | |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.033 | |
| transcription initiation from rna polymerase i promoter | GO:0006361 | 4 | 0.032 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.032 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.032 | |
| cation homeostasis | GO:0055080 | 212 | 0.032 | |
| endothelial cell migration | GO:0043542 | 44 | 0.031 | Human |
| basement membrane organization | GO:0071711 | 8 | 0.031 | |
| circulatory system process | GO:0003013 | 197 | 0.031 | |
| limb development | GO:0060173 | 166 | 0.031 | |
| cardiac ventricle morphogenesis | GO:0003208 | 50 | 0.031 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.030 | |
| defense response to other organism | GO:0098542 | 197 | 0.030 | |
| limb bud formation | GO:0060174 | 10 | 0.029 | |
| cardiac chamber morphogenesis | GO:0003206 | 93 | 0.029 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.029 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.028 | |
| pallium development | GO:0021543 | 120 | 0.028 | |
| transmembrane transport | GO:0055085 | 412 | 0.028 | |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001239 | 26 | 0.028 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.028 | |
| termination of rna polymerase i transcription | GO:0006363 | 2 | 0.027 | |
| response to inorganic substance | GO:0010035 | 96 | 0.027 | Rat |
| cardiac muscle cell differentiation | GO:0055007 | 69 | 0.027 | |
| response to bmp | GO:0071772 | 14 | 0.027 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 52 | 0.026 | |
| establishment of glial blood brain barrier | GO:0060857 | 2 | 0.026 | |
| angiogenesis | GO:0001525 | 201 | 0.026 | Human |
| retina development in camera type eye | GO:0060041 | 119 | 0.026 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.026 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.025 | |
| negative regulation of cell motility | GO:2000146 | 61 | 0.025 | |
| axon ensheathment | GO:0008366 | 76 | 0.025 | |
| protein processing | GO:0016485 | 163 | 0.025 | |
| telencephalon development | GO:0021537 | 186 | 0.025 | |
| positive regulation of cell morphogenesis involved in differentiation | GO:0010770 | 72 | 0.025 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.025 | |
| digestive tract development | GO:0048565 | 190 | 0.025 | Fly |
| notochord cell differentiation | GO:0060034 | 1 | 0.024 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.024 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.024 | |
| plasma membrane organization | GO:0007009 | 90 | 0.024 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.023 | |
| response to peptide hormone | GO:0043434 | 127 | 0.023 | Rat |
| negative regulation of cell development | GO:0010721 | 169 | 0.023 | |
| response to monoamine | GO:0071867 | 4 | 0.022 | |
| endochondral bone morphogenesis | GO:0060350 | 50 | 0.022 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.022 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.022 | |
| multicellular organismal aging | GO:0010259 | 24 | 0.022 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.022 | |
| metanephric glomerular basement membrane development | GO:0072274 | 1 | 0.021 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.021 | |
| cell junction assembly | GO:0034329 | 52 | 0.021 | |
| response to oxidative stress | GO:0006979 | 123 | 0.021 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.021 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.021 | |
| cellular response to bmp stimulus | GO:0071773 | 14 | 0.021 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.021 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.020 | |
| regulation of tooth mineralization | GO:0070170 | 2 | 0.020 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.020 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.020 | |
| defense response to fungus | GO:0050832 | 12 | 0.020 | |
| cardiac cell development | GO:0055006 | 41 | 0.020 | |
| membrane organization | GO:0061024 | 245 | 0.019 | |
| response to insulin | GO:0032868 | 100 | 0.019 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.019 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.019 | |
| glomerular basement membrane development | GO:0032836 | 8 | 0.019 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.018 | Human |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.018 | |
| oxidation reduction process | GO:0055114 | 342 | 0.018 | |
| bone development | GO:0060348 | 120 | 0.018 | |
| collagen metabolic process | GO:0032963 | 17 | 0.018 | |
| modulation by virus of host process | GO:0019054 | 2 | 0.018 | |
| regulation of phosphatidylcholine biosynthetic process | GO:2001245 | 2 | 0.018 | |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.018 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.017 | |
| muscle tissue morphogenesis | GO:0060415 | 53 | 0.017 | |
| cation transport | GO:0006812 | 399 | 0.017 | |
| integrin biosynthetic process | GO:0045112 | 1 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.017 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.017 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.016 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.016 | |
| positive regulation of peptide secretion | GO:0002793 | 33 | 0.016 | |
| regulation of angiogenesis | GO:0045765 | 81 | 0.016 | Human |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.016 | |
| defense response to bacterium | GO:0042742 | 119 | 0.016 | |
| blood circulation | GO:0008015 | 195 | 0.016 | |
| negative regulation of phagocytosis | GO:0050765 | 4 | 0.016 | |
| palate development | GO:0060021 | 76 | 0.016 | |
| regulation of blood circulation | GO:1903522 | 93 | 0.016 | |
| regeneration | GO:0031099 | 38 | 0.016 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.016 | Fly |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.016 | |
| lamellipodium organization | GO:0097581 | 29 | 0.016 | |
| cardiac ventricle development | GO:0003231 | 83 | 0.016 | |
| cardiac muscle cell development | GO:0055013 | 39 | 0.016 | |
| glycerophospholipid biosynthetic process | GO:0046474 | 32 | 0.016 | |
| regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity | GO:0031585 | 2 | 0.016 | |
| head morphogenesis | GO:0060323 | 34 | 0.015 | |
| protein localization to membrane | GO:0072657 | 108 | 0.015 | |
| bone morphogenesis | GO:0060349 | 78 | 0.015 | |
| integrin mediated signaling pathway | GO:0007229 | 27 | 0.015 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.015 | |
| ossification | GO:0001503 | 216 | 0.015 | Rat |
| lipid localization | GO:0010876 | 126 | 0.015 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.015 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.015 | |
| digestive system development | GO:0055123 | 200 | 0.015 | Fly |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.015 | |
| acylglycerol metabolic process | GO:0006639 | 55 | 0.014 | |
| positive regulation of growth | GO:0045927 | 104 | 0.014 | Worm |
| skin development | GO:0043588 | 220 | 0.014 | |
| cellular response to mechanical stimulus | GO:0071260 | 7 | 0.014 | |
| multicellular organism growth | GO:0035264 | 161 | 0.014 | Worm |
| gastrulation | GO:0007369 | 116 | 0.014 | |
| response to nutrient levels | GO:0031667 | 109 | 0.014 | Rat |
| cellular response to thyroid hormone stimulus | GO:0097067 | 1 | 0.014 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.014 | |
| amine metabolic process | GO:0009308 | 45 | 0.014 | |
| negative regulation of protein activation cascade | GO:2000258 | 3 | 0.014 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.014 | |
| ventricular cardiac muscle tissue morphogenesis | GO:0055010 | 32 | 0.014 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.014 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.014 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.014 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.014 | |
| actin filament polymerization | GO:0030041 | 44 | 0.014 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.014 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.013 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.013 | |
| protein folding | GO:0006457 | 28 | 0.013 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.013 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.013 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.013 | |
| positive regulation of myeloid cell apoptotic process | GO:0033034 | 4 | 0.013 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.013 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.013 | |
| cell cell junction organization | GO:0045216 | 72 | 0.013 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.013 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.013 | |
| negative regulation of cell adhesion | GO:0007162 | 45 | 0.013 | |
| negative regulation of bmp signaling pathway | GO:0030514 | 35 | 0.013 | |
| negative regulation of blood vessel morphogenesis | GO:2000181 | 25 | 0.012 | Human |
| protein catabolic process | GO:0030163 | 221 | 0.012 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.012 | |
| substrate adhesion dependent cell spreading | GO:0034446 | 30 | 0.012 | |
| collagen biosynthetic process | GO:0032964 | 7 | 0.012 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.012 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.012 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.012 | |
| muscle cell development | GO:0055001 | 133 | 0.012 | |
| response to thyroid hormone | GO:0097066 | 2 | 0.012 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.012 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.012 | |
| regulation of secretion | GO:0051046 | 274 | 0.012 | |
| organelle fission | GO:0048285 | 170 | 0.012 | |
| negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902176 | 4 | 0.012 | |
| chondroitin sulfate metabolic process | GO:0030204 | 17 | 0.012 | |
| positive regulation of metanephric mesenchymal cell migration | GO:2000591 | 1 | 0.012 | |
| myosin filament assembly | GO:0031034 | 2 | 0.012 | |
| response to radiation | GO:0009314 | 165 | 0.012 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.012 | |
| negative regulation of tooth mineralization | GO:0070171 | 1 | 0.011 | |
| cell chemotaxis | GO:0060326 | 81 | 0.011 | |
| hair follicle morphogenesis | GO:0031069 | 29 | 0.011 | |
| cartilage development | GO:0051216 | 140 | 0.011 | Zebrafish |
| regulation of binding | GO:0051098 | 111 | 0.011 | |
| nephron development | GO:0072006 | 109 | 0.011 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.011 | |
| positive regulation of camp metabolic process | GO:0030816 | 19 | 0.011 | |
| negative regulation of peptidase activity | GO:0010466 | 46 | 0.011 | |
| spermatogenesis | GO:0007283 | 284 | 0.011 | |
| detection of chemical stimulus involved in sensory perception of taste | GO:0050912 | 3 | 0.011 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.011 | |
| regulation of endothelial cell apoptotic process | GO:2000351 | 9 | 0.011 | |
| vegf activated neuropilin signaling pathway involved in axon guidance | GO:1902378 | 1 | 0.011 | |
| endoderm formation | GO:0001706 | 20 | 0.011 | |
| negative regulation of neuron migration | GO:2001223 | 6 | 0.011 | |
| mapk cascade | GO:0000165 | 281 | 0.011 | |
| apical constriction | GO:0003383 | 4 | 0.011 | |
| tissue migration | GO:0090130 | 68 | 0.011 | Human |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.011 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.011 | |
| striated muscle contraction | GO:0006941 | 45 | 0.011 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.011 | |
| cellular water homeostasis | GO:0009992 | 2 | 0.011 | |
| cell growth | GO:0016049 | 130 | 0.011 | |
| t cell activation | GO:0042110 | 289 | 0.010 | |
| positive regulation of ion transport | GO:0043270 | 65 | 0.010 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.010 | |
| synaptic transmission | GO:0007268 | 329 | 0.010 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.010 | |
| regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway | GO:1900238 | 1 | 0.010 | |
| organic acid transport | GO:0015849 | 101 | 0.010 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.010 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.010 | |
| regulation of neuron migration | GO:2001222 | 22 | 0.010 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.010 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.010 | |
| glucose homeostasis | GO:0042593 | 128 | 0.010 | |
| visual learning | GO:0008542 | 44 | 0.010 | |
| mitochondrion organization | GO:0007005 | 134 | 0.010 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.010 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.010 | |