Mus musculus

0 known processes

C1s

complement component 1, s subcomponent

(Aliases: AI255193,MGC37773,AA959438,C1sa,AI327365,MGC132830)

C1s biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein activation cascadeGO:0072376190.608
Mouse
activation of immune responseGO:00022531380.569
Mouse
regulation of peptidase activityGO:0052547960.251
immune effector processGO:00022523210.232
Mouse
complement activationGO:0006956160.219
Mouse
regulation of complement activationGO:003044970.146
extracellular structure organizationGO:00430621480.138
extracellular matrix organizationGO:00301981470.127
innate immune responseGO:00450871570.123
Mouse
regulation of cytokine productionGO:00018172660.111
humoral immune responseGO:0006959570.105
Mouse
negative regulation of complement activationGO:004591630.102
cytokine productionGO:00018163190.093
regulation of endopeptidase activityGO:0052548890.091
regulation of proteolysisGO:00301621640.091
protein processingGO:00164851630.087
response to lipopolysaccharideGO:00324961280.086
negative regulation of tooth mineralizationGO:007017110.084
negative regulation of odontogenesisGO:004248330.079
cell adhesionGO:00071553290.076
oxidation reduction processGO:00551143420.076
negative regulation of proteolysisGO:0045861740.073
negative regulation of protein metabolic processGO:00512482820.072
leukocyte mediated immunityGO:00024431740.071
protein maturationGO:00516041760.071
angiogenesisGO:00015252010.066
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.066
positive regulation of cytokine productionGO:00018191740.065
regulation of hydrolase activityGO:00513362460.062
regulation of innate immune responseGO:0045088910.061
negative regulation of molecular functionGO:00440922580.057
lymphocyte mediated immunityGO:00024491390.054
complement activation lectin pathwayGO:000186750.054
Mouse
positive regulation of defense responseGO:00313491240.053
negative regulation of cell proliferationGO:00082852960.053
negative regulation of protein activation cascadeGO:200025830.052
response to molecule of bacterial originGO:00022371430.052
cell substrate adhesionGO:00315891300.049
wound healingGO:00420601570.046
biomineral tissue developmentGO:0031214640.045
production of molecular mediator of immune responseGO:00024401030.044
glycoprotein metabolic processGO:00091001160.044
chondroitin sulfate proteoglycan metabolic processGO:0050654200.044
urogenital system developmentGO:00016552610.043
cellular response to cytokine stimulusGO:00713451890.042
cellular amine metabolic processGO:0044106440.041
regulation of inflammatory responseGO:00507271470.040
small gtpase mediated signal transductionGO:0007264970.040
positive regulation of protein modification processGO:00314012990.040
sulfur compound metabolic processGO:00067901000.038
cytokine mediated signaling pathwayGO:00192211150.037
cellular response to molecule of bacterial originGO:0071219830.037
proteoglycan metabolic processGO:0006029380.036
cation transportGO:00068123990.035
collagen fibril organizationGO:0030199320.035
defense response to other organismGO:00985421970.034
regulation of vasculature developmentGO:1901342880.032
regulation of cell adhesionGO:00301551540.032
negative regulation of endopeptidase activityGO:0010951440.032
kidney developmentGO:00018222130.032
transmembrane transportGO:00550854120.031
defense response to bacteriumGO:00427421190.031
negative regulation of hydrolase activityGO:0051346710.031
negative regulation of cellular protein metabolic processGO:00322692470.031
cellular response to growth factor stimulusGO:00713631970.031
regulation of cell migrationGO:00303342190.031
cellular lipid metabolic processGO:00442553230.030
activation of membrane attack complexGO:000190540.030
sterol metabolic processGO:0016125580.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.029
mucopolysaccharide metabolic processGO:1903510250.028
blood vessel morphogenesisGO:00485142850.028
protein import into nucleusGO:0006606950.028
regulation of protein processingGO:0070613960.028
tissue remodelingGO:00487711020.027
cellular ketone metabolic processGO:0042180840.027
anatomical structure homeostasisGO:00602491450.027
positive regulation of activation of membrane attack complexGO:000197020.027
regulation of acute inflammatory responseGO:0002673270.027
regulation of response to woundingGO:19030341890.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.027
regulation of angiogenesisGO:0045765810.027
regulation of cellular ketone metabolic processGO:0010565660.027
mapk cascadeGO:00001652810.027
regulation of ras protein signal transductionGO:00465781140.026
cytoplasmic transportGO:00164822340.026
regulation of cellular amine metabolic processGO:0033238200.026
positive regulation of peptidase activityGO:0010952490.026
positive regulation of cellular amine metabolic processGO:003324050.026
chondroitin sulfate metabolic processGO:0030204170.026
amine metabolic processGO:0009308450.025
regulation of adaptive immune responseGO:0002819900.025
peptidyl amino acid modificationGO:00181933360.025
nucleoside phosphate metabolic processGO:00067533380.025
response to growth factorGO:00708481980.025
gland developmentGO:00487323300.024
epithelial cell proliferationGO:00506731740.024
macromolecule catabolic processGO:00090572810.024
carbohydrate homeostasisGO:00335001280.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
regulation of defense responseGO:00313472330.023
carbohydrate metabolic processGO:00059752300.023
circulatory system processGO:00030131970.023
fat cell differentiationGO:00454441600.023
regulation of tooth mineralizationGO:007017020.023
regulation of lymphocyte mediated immunityGO:0002706840.022
regulation of kinase activityGO:00435492490.022
rho protein signal transductionGO:0007266320.022
regulation of cell activationGO:00508652890.022
antibacterial peptide biosynthetic processGO:000278020.022
response to acid chemicalGO:00011011110.022
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.022
positive regulation of immune effector processGO:00026991070.022
blood circulationGO:00080151950.021
response to interferon gammaGO:0034341340.021
cellular response to organonitrogen compoundGO:00714171450.021
nucleotide metabolic processGO:00091173320.021
ras protein signal transductionGO:0007265770.021
reactive oxygen species biosynthetic processGO:190340980.021
negative regulation of phosphorus metabolic processGO:00105631840.020
regulation of protein activation cascadeGO:200025770.020
negative regulation of epithelial cell proliferationGO:0050680640.020
reactive oxygen species metabolic processGO:0072593840.020
cartilage developmentGO:00512161400.020
response to steroid hormoneGO:0048545560.020
aromatic compound catabolic processGO:00194392860.020
respiratory system developmentGO:00605411900.019
peptide metabolic processGO:0006518460.019
nucleoside phosphate catabolic processGO:19012922220.019
negative regulation of protein maturationGO:1903318790.019
lipid biosynthetic processGO:00086101790.019
connective tissue developmentGO:00614481790.019
regulation of glucose metabolic processGO:0010906600.019
positive regulation of protein phosphorylationGO:00019342420.019
negative regulation of peptidase activityGO:0010466460.019
organic cyclic compound catabolic processGO:19013612950.019
camera type eye developmentGO:00430102660.019
regulation of blood pressureGO:0008217930.019
inorganic ion transmembrane transportGO:00986602340.019
t cell activationGO:00421102890.019
positive regulation of protein kinase activityGO:00458601440.018
regulation of system processGO:00440572000.018
phagocytosisGO:0006909660.018
regulation of apoptotic signaling pathwayGO:20012331970.018
fatty acid metabolic processGO:00066311210.018
regulation of epithelial cell proliferationGO:00506781410.018
physiological muscle hypertrophyGO:000329830.018
negative regulation of protein processingGO:0010955790.018
cellular response to biotic stimulusGO:0071216920.018
positive regulation of cell substrate adhesionGO:0010811470.018
negative regulation of immune system processGO:00026832090.018
nitrogen compound transportGO:00717052710.018
transforming growth factor beta receptor signaling pathwayGO:0007179710.018
iron ion import into cellGO:009745940.017
positive regulation of apoptotic cell clearanceGO:200042730.017
transition metal ion transportGO:0000041380.017
cellular response to lipopolysaccharideGO:0071222770.017
cellular response to lipidGO:00713961450.017
heterocycle catabolic processGO:00467002800.017
cellular amino acid metabolic processGO:00065201030.017
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.017
triglyceride metabolic processGO:0006641510.017
monocarboxylic acid metabolic processGO:00327871910.017
regulation of hormone levelsGO:00108172110.017
regulation of secretion by cellGO:19035302490.017
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.017
response to oxidative stressGO:00069791230.016
response to organic cyclic compoundGO:00140701980.016
Rat
inflammatory responseGO:00069542440.016
regulation of mapk cascadeGO:00434082480.016
positive regulation of endocytosisGO:0045807420.016
regulation of blood vessel sizeGO:0050880560.016
ion transmembrane transportGO:00342203610.016
homeostasis of number of cellsGO:00488722100.016
positive regulation of protein kinase b signalingGO:0051897320.016
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.016
monosaccharide metabolic processGO:00059961060.016
regulation of reactive oxygen species metabolic processGO:2000377400.016
apoptotic signaling pathwayGO:00971903060.016
sensory system developmentGO:004888030.016
cytokine production involved in immune responseGO:0002367340.016
cellular macromolecule catabolic processGO:00442652060.015
muscle tissue developmentGO:00605373080.015
organonitrogen compound biosynthetic processGO:19015661920.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
regulation of cellular catabolic processGO:00313292420.015
negative regulation of phosphorylationGO:00423261660.015
regulation of cellular response to stressGO:00801351590.015
protein modification by small protein conjugation or removalGO:00706472070.015
multicellular organismal homeostasisGO:00488711640.015
regulation of secretionGO:00510462740.015
negative regulation of immune effector processGO:0002698550.015
muscle cell differentiationGO:00426922610.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
respiratory tube developmentGO:00303231670.015
peptide cross linkingGO:0018149100.015
regulation of fatty acid biosynthetic processGO:0042304120.015
positive regulation of kinase activityGO:00336741550.014
nucleoside triphosphate metabolic processGO:00091412300.014
cation transmembrane transportGO:00986552660.014
positive regulation of innate immune responseGO:0045089800.014
renal system developmentGO:00720012250.014
organ growthGO:00352651170.014
regulation of toll like receptor 4 signaling pathwayGO:003414340.014
negative regulation of cellular component organizationGO:00511291940.014
cellular response to hormone stimulusGO:00328701500.014
regulation of systemic arterial blood pressureGO:0003073610.014
spermatogenesisGO:00072832840.014
cellular nitrogen compound catabolic processGO:00442702800.014
purine nucleoside triphosphate catabolic processGO:00091462030.014
lymphocyte proliferationGO:00466511640.014
positive regulation of cell activationGO:00508671580.014
cell type specific apoptotic processGO:00972852680.014
morphogenesis of a branching epitheliumGO:00611381930.014
glucose transportGO:0015758560.014
nucleobase containing small molecule metabolic processGO:00550863520.014
ribose phosphate metabolic processGO:00196932910.014
regulation of fat cell differentiationGO:0045598810.014
positive regulation of glucose transportGO:0010828160.014
regulation of glucose transportGO:0010827320.014
glucose homeostasisGO:00425931280.014
response to decreased oxygen levelsGO:0036293590.013
activation of innate immune responseGO:0002218560.013
prostate gland developmentGO:0030850480.013
positive regulation of cell adhesionGO:0045785800.013
monocarboxylic acid biosynthetic processGO:0072330610.013
response to radiationGO:00093141650.013
multicellular organismal macromolecule metabolic processGO:0044259190.013
regulation of neuron differentiationGO:00456642810.013
monosaccharide transportGO:0015749580.013
regulation of lymphocyte proliferationGO:00506701170.013
regulation of odontogenesisGO:0042481180.013
regulation of carbohydrate metabolic processGO:0006109750.013
epidermis developmentGO:00085441870.013
regulation of lipid metabolic processGO:00192161180.013
lateral line system developmentGO:004892510.013
positive regulation of hydrolase activityGO:00513451480.013
interleukin 1 productionGO:0032612310.013
organic hydroxy compound metabolic processGO:19016152030.013
immunoglobulin mediated immune responseGO:0016064690.013
cell matrix adhesionGO:0007160680.013
leukocyte migrationGO:00509001240.013
glycosaminoglycan metabolic processGO:0030203340.013
posttranscriptional regulation of gene expressionGO:00106081550.013
negative regulation of growthGO:0045926990.013
positive regulation of programmed cell deathGO:00430682180.013
peptidyl tyrosine modificationGO:00182121450.013
leukocyte chemotaxisGO:0030595690.013
proteolysis involved in cellular protein catabolic processGO:00516031470.013
epithelial tube morphogenesisGO:00605623030.013
protein catabolic processGO:00301632210.013
regulation of cellular component biogenesisGO:00440871810.013
positive regulation of apoptotic processGO:00430652170.013
glycerolipid metabolic processGO:00464861220.013
immune response activating signal transductionGO:00027571160.013
positive regulation of nervous system developmentGO:00519622210.013
female sex differentiationGO:0046660840.013
lung developmentGO:00303241640.013
positive regulation of proteolysisGO:0045862850.013
endocytosisGO:00068971680.012
regulation of leukocyte mediated immunityGO:00027031040.012
regulation of protein transportGO:00512231630.012
anion transportGO:00068201770.012
positive regulation of cell deathGO:00109422240.012
cellularizationGO:000734910.012
chemotaxisGO:00069352470.012
skeletal system developmentGO:00015013560.012
response to peptideGO:19016521360.012
organic acid biosynthetic processGO:0016053860.012
t cell mediated cytotoxicityGO:0001913260.012
male gamete generationGO:00482322850.012
skeletal system morphogenesisGO:00487052030.012
neuron deathGO:00709971540.012
regulation of establishment of protein localizationGO:00702011810.012
bone developmentGO:00603481200.012
regulation of removal of superoxide radicalsGO:200012140.012
positive regulation of inflammatory responseGO:0050729470.012
regulation of cellular amino acid metabolic processGO:000652150.012
cell cell adhesionGO:0098609410.012
nuclear transportGO:00511691390.012
lymphocyte activation involved in immune responseGO:0002285930.012
cellular carbohydrate metabolic processGO:00442621190.012
regulation of anatomical structure sizeGO:00900661780.012
synapse organizationGO:00508081250.012
cellular protein catabolic processGO:00442571550.012
peptidyl serine modificationGO:0018209830.012
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.012
leukocyte mediated cytotoxicityGO:0001909620.012
response to transforming growth factor betaGO:0071559880.012
physiological cardiac muscle hypertrophyGO:000330130.012
negative regulation of fat cell differentiationGO:0045599360.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.012
negative regulation of defense responseGO:0031348770.012
multicellular organismal signalingGO:0035637910.011
protein localization to organelleGO:00333651850.011
regulation of cell projection organizationGO:00313442060.011
inorganic cation transmembrane transportGO:00986622070.011
cellular homeostasisGO:00197252400.011
cofactor metabolic processGO:0051186800.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.011
erk1 and erk2 cascadeGO:0070371770.011
transmission of nerve impulseGO:0019226760.011
positive regulation of chemotaxisGO:0050921380.011
regulation of protein secretionGO:0050708820.011
type b pancreatic cell proliferationGO:0044342100.011
striated muscle tissue developmentGO:00147062930.011
hexose transportGO:0008645560.011
cell activation involved in immune responseGO:00022631260.011
autophagyGO:0006914450.011
renal system processGO:0003014480.011
divalent inorganic cation transportGO:00725111780.011
carboxylic acid biosynthetic processGO:0046394860.011
regulation of cellular response to growth factor stimulusGO:0090287820.011
cellular response to steroid hormone stimulusGO:0071383330.011
positive regulation of cytokine secretionGO:0050715410.011
negative regulation of protein modification processGO:00314001630.011
cell growthGO:00160491300.011
small molecule biosynthetic processGO:00442831320.011
cellular chemical homeostasisGO:00550822150.011
regulation of blood vessel size by renin angiotensinGO:000203450.011
protein targetingGO:00066051430.011
protein kinase b signalingGO:0043491740.011
regulation of humoral immune responseGO:0002920220.011
regulation of lymphocyte activationGO:00512492400.011
skin developmentGO:00435882200.010
carboxylic acid transportGO:00469421000.010
macromolecule glycosylationGO:0043413550.010
carbohydrate transportGO:0008643620.010
regulation of body fluid levelsGO:00508781620.010
microtubule based processGO:00070172360.010
iron ion homeostasisGO:0055072360.010
metal ion homeostasisGO:00550651890.010
ribonucleotide metabolic processGO:00092592910.010
positive regulation of response to woundingGO:1903036660.010
response to oxygen levelsGO:0070482620.010
carbohydrate derivative biosynthetic processGO:19011371830.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.010
hexose biosynthetic processGO:0019319390.010
lipid catabolic processGO:0016042690.010
positive regulation of lymphocyte activationGO:00512511400.010
purine nucleotide metabolic processGO:00061633020.010
endocrine processGO:0050886390.010
regulation of organelle organizationGO:00330432890.010
fatty acid biosynthetic processGO:0006633410.010
positive regulation of protein activation cascadeGO:200025920.010
regulation of cell growth involved in cardiac muscle cell developmentGO:006105030.010

C1s disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hematopoietic system diseaseDOID:7400.091
disease of anatomical entityDOID:700.091
hemolytic anemiaDOID:58300.091
immune system diseaseDOID:291400.091
hemolytic uremic syndromeDOID:1255400.091
anemiaDOID:235500.091
normocytic anemiaDOID:72000.091
retinal diseaseDOID:567900.040
nervous system diseaseDOID:86300.040
eye diseaseDOID:561400.040
sensory system diseaseDOID:005015500.040
eye and adnexa diseaseDOID:149200.040
retinal degenerationDOID:846600.034
inherited metabolic disorderDOID:65500.020
disease of metabolismDOID:001466700.020
musculoskeletal system diseaseDOID:1700.018
connective tissue diseaseDOID:6500.018
integumentary system diseaseDOID:1600.015
macular degenerationDOID:444800.012
degeneration of macula and posterior poleDOID:200700.012
age related macular degenerationDOID:1087100.012