Mus musculus

21 known processes

Slco1a1

solute carrier organic anion transporter family, member 1a1

(Aliases: OATP-1,Oatp1,A530084B21,Slc21a1)

Slco1a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glucuronate metabolic processGO:001958520.917
uronic acid metabolic processGO:000606320.905
monocarboxylic acid metabolic processGO:00327871910.542
Mouse
cellular response to testosterone stimulusGO:007139410.453
naphthalene metabolic processGO:001893110.346
oxidation reduction processGO:00551143420.286
oxidative demethylationGO:007098910.227
cellular lipid metabolic processGO:00442553230.184
response to testosteroneGO:003357430.176
response to organic cyclic compoundGO:00140701980.160
cellular response to hormone stimulusGO:00328701500.156
carbohydrate metabolic processGO:00059752300.153
inter male aggressive behaviorGO:000212130.132
establishment of blood nerve barrierGO:000806530.130
regulation of cellular ketone metabolic processGO:0010565660.121
cellular ketone metabolic processGO:0042180840.112
secondary alcohol metabolic processGO:190265230.108
vitamin d biosynthetic processGO:004236830.108
naphthalene containing compound metabolic processGO:009042010.106
cellular amino acid metabolic processGO:00065201030.105
organic hydroxy compound metabolic processGO:19016152030.103
Mouse
cellular response to lipidGO:00713961450.103
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressureGO:000199830.102
fatty acid metabolic processGO:00066311210.102
small molecule catabolic processGO:0044282710.099
lipid catabolic processGO:0016042690.095
cellular alcohol biosynthetic processGO:004410830.091
regulation of cellular amino acid metabolic processGO:000652150.089
cellular response to cadmium ionGO:007127630.086
steroid metabolic processGO:00082021190.083
Mouse
fatty acid derivative metabolic processGO:1901568330.082
negative regulation of lipid metabolic processGO:0045833300.080
vitamin d3 metabolic processGO:007064030.078
calcitriol biosynthetic process from calciolGO:003637830.076
nitrogen compound transportGO:00717052710.074
immune effector processGO:00022523210.067
unsaturated fatty acid metabolic processGO:0033559310.067
icosanoid metabolic processGO:0006690330.065
cofactor metabolic processGO:0051186800.065
Mouse
cellular response to steroid hormone stimulusGO:0071383330.065
monosaccharide metabolic processGO:00059961060.064
positive regulation of cellular amino acid metabolic processGO:004576430.064
positive regulation of secretion by cellGO:19035321140.060
response to steroid hormoneGO:0048545560.059
innate immune responseGO:00450871570.058
lipid localizationGO:00108761260.058
positive regulation of cellular amine metabolic processGO:003324050.057
transmembrane transportGO:00550854120.057
organic cyclic compound catabolic processGO:19013612950.056
progesterone metabolic processGO:004244840.056
alcohol metabolic processGO:00060661160.056
protein maturationGO:00516041760.056
lipid biosynthetic processGO:00086101790.055
fat soluble vitamin biosynthetic processGO:004236240.053
cellular response to organic cyclic compoundGO:0071407870.053
macromolecule glycosylationGO:0043413550.052
response to phenylpropanoidGO:0080184220.050
cellular alcohol metabolic processGO:004410730.050
maintenance of locationGO:0051235890.049
glycosylationGO:0070085620.047
small molecule biosynthetic processGO:00442831320.047
response to organonitrogen compoundGO:00102432460.047
cellular response to foodGO:007124010.046
long chain fatty acid metabolic processGO:0001676260.046
organic acid transportGO:00158491010.045
cellular amine metabolic processGO:0044106440.045
lymphocyte mediated immunityGO:00024491390.045
cytoplasmic transportGO:00164822340.044
activation of immune responseGO:00022531380.044
sensory perception of chemical stimulusGO:0007606510.043
neutral lipid metabolic processGO:0006638570.043
organic acid catabolic processGO:0016054510.042
heme metabolic processGO:0042168160.042
Mouse
regulation of secretionGO:00510462740.041
response to oxidative stressGO:00069791230.041
regulation of cytokine productionGO:00018172660.040
cation transportGO:00068123990.040
regulation of feeding behaviorGO:006025930.039
negative regulation of immune effector processGO:0002698550.039
positive regulation of protein modification processGO:00314012990.039
regulation of secretion by cellGO:19035302490.039
porphyrin containing compound metabolic processGO:0006778220.038
Mouse
regulation of cellular amine metabolic processGO:0033238200.038
regulation of vesicle mediated transportGO:00606271390.038
organic hydroxy compound biosynthetic processGO:1901617770.037
saturated monocarboxylic acid metabolic processGO:003278820.037
peptidyl amino acid modificationGO:00181933360.037
lipid storageGO:0019915360.036
androgen biosynthetic processGO:000670240.036
cellular lipid catabolic processGO:0044242520.036
renal tubular secretionGO:009725420.036
ion transmembrane transportGO:00342203610.036
response to xenobiotic stimulusGO:0009410130.035
Mouse
response to stilbenoidGO:0035634220.035
aromatic compound catabolic processGO:00194392860.035
cellular aldehyde metabolic processGO:0006081120.034
anion transportGO:00068201770.034
organic hydroxy compound catabolic processGO:1901616250.034
glycoprotein metabolic processGO:00091001160.034
amine metabolic processGO:0009308450.034
carboxylic acid biosynthetic processGO:0046394860.033
primary alcohol catabolic processGO:003431020.033
cell adhesionGO:00071553290.033
sensory perceptionGO:00076002450.031
regulation of protein processingGO:0070613960.031
mapk cascadeGO:00001652810.031
organic acid biosynthetic processGO:0016053860.031
testosterone biosynthetic processGO:006137020.031
regulation of lymphocyte activationGO:00512492400.030
protein localization to organelleGO:00333651850.030
positive regulation of protein phosphorylationGO:00019342420.030
cellular homeostasisGO:00197252400.030
negative regulation of hormone metabolic processGO:003235140.030
protein processingGO:00164851630.030
carboxylic acid transportGO:00469421000.029
response to peptide hormoneGO:00434341270.029
glycosyl compound metabolic processGO:19016572460.029
protein localization to nucleusGO:00345041210.029
cellular response to ketoneGO:1901655120.028
reactive oxygen species metabolic processGO:0072593840.028
quinone metabolic processGO:190166170.028
t cell activationGO:00421102890.028
inorganic cation transmembrane transportGO:00986622070.028
regulation of ion transportGO:00432692150.027
cellular response to peptide hormone stimulusGO:0071375920.027
leukocyte mediated immunityGO:00024431740.026
regulation of leukocyte mediated immunityGO:00027031040.026
divalent inorganic cation transportGO:00725111780.026
alcohol biosynthetic processGO:0046165430.026
organonitrogen compound catabolic processGO:19015652640.026
monocarboxylic acid transportGO:0015718440.026
regulation of inflammatory responseGO:00507271470.026
glycerolipid metabolic processGO:00464861220.026
sulfur compound metabolic processGO:00067901000.026
calcium ion transportGO:00068161590.026
positive regulation of steroid hormone secretionGO:200083320.026
regulation of protein kinase activityGO:00458592320.025
negative regulation of immune system processGO:00026832090.025
response to lipopolysaccharideGO:00324961280.025
cellular chemical homeostasisGO:00550822150.025
regulation of anatomical structure sizeGO:00900661780.025
endocytosisGO:00068971680.025
cytokine productionGO:00018163190.025
positive regulation of estrogen secretionGO:200086310.025
arachidonic acid metabolic processGO:0019369140.025
positive regulation of secretionGO:00510471300.025
linoleic acid metabolic processGO:004365160.025
humoral immune responseGO:0006959570.024
organic anion transportGO:00157111370.024
divalent metal ion transportGO:00708381720.024
regulation of cell activationGO:00508652890.024
glycoprotein biosynthetic processGO:0009101890.024
protein glycosylationGO:0006486550.024
regulation of hormone levelsGO:00108172110.024
regulation of complement activationGO:003044970.024
lymphocyte differentiationGO:00300982420.024
regulation of estrogen secretionGO:200086110.024
heterocycle catabolic processGO:00467002800.024
regulation of neurotransmitter levelsGO:0001505870.024
regulation of peptidase activityGO:0052547960.023
lipid transportGO:0006869980.023
bile acid and bile salt transportGO:001572150.023
regulation of protein localizationGO:00328802310.023
response to peptideGO:19016521360.023
carboxylic acid catabolic processGO:0046395510.022
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117940.022
hematopoietic progenitor cell differentiationGO:00022441430.022
regulation of t cell activationGO:00508631700.022
protein modification by small protein conjugation or removalGO:00706472070.022
negative regulation of gluconeogenesisGO:004572190.022
regulation of protein maturationGO:1903317960.022
regulation of neuron apoptotic processGO:00435231220.022
intracellular protein transportGO:00068862040.022
short chain fatty acid catabolic processGO:001962620.022
blood vessel morphogenesisGO:00485142850.021
response to cadmium ionGO:004668680.021
response to metal ionGO:0010038470.021
bile acid metabolic processGO:0008206170.021
Mouse
mitochondrion organizationGO:00070051340.021
cell substrate adhesionGO:00315891300.021
macromolecule catabolic processGO:00090572810.021
response to molecule of bacterial originGO:00022371430.021
positive regulation of cytokine productionGO:00018191740.021
muscle cell differentiationGO:00426922610.020
monocarboxylic acid biosynthetic processGO:0072330610.020
membrane organizationGO:00610242450.020
steroid biosynthetic processGO:0006694470.020
carnitine transportGO:001587930.020
carbohydrate derivative biosynthetic processGO:19011371830.020
negative regulation of protein processingGO:0010955790.020
negative regulation of cellular protein metabolic processGO:00322692470.020
lymphocyte proliferationGO:00466511640.020
cellular response to ethanolGO:007136130.020
cell type specific apoptotic processGO:00972852680.019
gluconeogenesisGO:0006094390.019
apoptotic signaling pathwayGO:00971903060.019
positive regulation of apoptotic processGO:00430652170.019
adaptive immune responseGO:00022501550.019
positive regulation of insulin receptor signaling pathwayGO:004662840.019
positive regulation of blood pressureGO:0045777210.019
regulation of proteolysisGO:00301621640.019
amide transportGO:00428861380.019
regulation of ketone biosynthetic processGO:001056620.019
protein oligomerizationGO:0051259670.018
cellular ion homeostasisGO:00068731650.018
hormone metabolic processGO:0042445860.018
estrogen secretionGO:003593710.018
immunoglobulin mediated immune responseGO:0016064690.018
carbohydrate derivative catabolic processGO:19011362310.018
regulation of protein activation cascadeGO:200025770.018
response to growth factorGO:00708481980.018
cation transmembrane transportGO:00986552660.018
cellular response to organonitrogen compoundGO:00714171450.018
regulation of hydrolase activityGO:00513362460.018
multicellular organism growthGO:00352641610.018
Mouse
negative regulation of leukocyte mediated immunityGO:0002704290.018
demethylationGO:0070988230.018
alcohol catabolic processGO:0046164160.018
renal system process involved in regulation of systemic arterial blood pressureGO:0003071150.017
regulation of apoptotic signaling pathwayGO:20012331970.017
wound healingGO:00420601570.017
b cell differentiationGO:0030183780.017
peptide transportGO:00158331330.017
carbohydrate biosynthetic processGO:0016051740.017
negative regulation of cellular amino acid metabolic processGO:004576300.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.017
positive regulation of protein serine threonine kinase activityGO:00719021060.017
male sex differentiationGO:00466611090.017
nucleobase containing small molecule metabolic processGO:00550863520.017
locomotory behaviorGO:00076261950.017
regulation of homeostatic processGO:00328441820.017
vitamin metabolic processGO:0006766230.017
nucleoside phosphate catabolic processGO:19012922220.017
positive regulation of dopamine uptake involved in synaptic transmissionGO:005158620.017
female meiosis chromosome segregationGO:001632110.016
cellular response to inorganic substanceGO:0071241370.016
acylglycerol metabolic processGO:0006639550.016
regulation of lymphocyte mediated immunityGO:0002706840.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
protein kinase b signalingGO:0043491740.016
inflammatory responseGO:00069542440.016
positive regulation of cell deathGO:00109422240.016
cellular response to growth factor stimulusGO:00713631970.016
cell growthGO:00160491300.016
protein targetingGO:00066051430.016
male gamete generationGO:00482322850.016
tetrapyrrole metabolic processGO:0033013220.016
Mouse
negative regulation of proteolysisGO:0045861740.016
regulation of response to woundingGO:19030341890.016
peptidyl serine modificationGO:0018209830.016
regulation of cellular catabolic processGO:00313292420.015
nucleoside triphosphate metabolic processGO:00091412300.015
positive regulation of protein transportGO:0051222930.015
positive regulation of protein kinase activityGO:00458601440.015
protein catabolic processGO:00301632210.015
negative regulation of molecular functionGO:00440922580.015
isoprenoid metabolic processGO:0006720290.015
inorganic ion transmembrane transportGO:00986602340.015
insulin receptor signaling pathwayGO:0008286490.015
response to oxygen levelsGO:0070482620.015
cellular response to nutrient levelsGO:0031669640.015
chemotaxisGO:00069352470.015
regulation of establishment of protein localizationGO:00702011810.015
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.015
response to inorganic substanceGO:0010035960.015
regulation of neuron deathGO:19012141340.015
anion transmembrane transportGO:0098656710.015
purine nucleoside metabolic processGO:00422782410.015
regulation of defense responseGO:00313472330.015
cellular response to insulin stimulusGO:0032869780.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
cellular nitrogen compound catabolic processGO:00442702800.015
response to ketoneGO:1901654150.014
purine nucleotide metabolic processGO:00061633020.014
establishment of protein localization to organelleGO:00725941180.014
carbohydrate homeostasisGO:00335001280.014
cellular divalent inorganic cation homeostasisGO:00725031270.014
catecholamine uptakeGO:009049340.014
regulation of protein kinase b signalingGO:0051896560.014
regulation of metal ion transportGO:00109591060.014
negative regulation of cellular amine metabolic processGO:003323910.014
gonad developmentGO:00084061410.014
regulation of mapk cascadeGO:00434082480.014
angiogenesisGO:00015252010.014
nucleocytoplasmic transportGO:00069131390.014
sequestering of metal ionGO:0051238190.014
cellular response to starvationGO:0009267570.014
positive regulation of activation of membrane attack complexGO:000197020.014
response to acid chemicalGO:00011011110.014
monocarboxylic acid catabolic processGO:0072329270.014
positive regulation of hydrolase activityGO:00513451480.014
protein modification by small protein conjugationGO:00324461870.014
nucleoside metabolic processGO:00091162460.014
fatty acid catabolic processGO:0009062250.013
cellular response to dna damage stimulusGO:00069742070.013
cytokine metabolic processGO:0042107710.013
defense response to other organismGO:00985421970.013
regulation of membrane potentialGO:00423911920.013
positive regulation of programmed cell deathGO:00430682180.013
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.013
skin developmentGO:00435882200.013
regulation of t cell proliferationGO:0042129920.013
glucose metabolic processGO:0006006920.013
carnitine transmembrane transportGO:190260330.013
purine containing compound metabolic processGO:00725213110.013
cellular response to oxidative stressGO:0034599760.013
positive regulation of lipid transportGO:0032370220.013
response to radiationGO:00093141650.013
cytokine biosynthetic processGO:0042089680.013
response to insulinGO:00328681000.013
negative regulation of cell proliferationGO:00082852960.013
fat cell differentiationGO:00454441600.013
hexose biosynthetic processGO:0019319390.013
cytokine secretionGO:0050663720.013
cellular response to peptideGO:1901653920.013
positive regulation of growthGO:00459271040.013
positive regulation of reactive oxygen species metabolic processGO:2000379110.013
regulation of adaptive immune responseGO:0002819900.013
regulation of cell cycleGO:00517262810.013
amino acid transportGO:0006865610.013
positive regulation of phagocytosisGO:0050766260.012
regulation of intracellular transportGO:00323861590.012
regulation of system processGO:00440572000.012
astrocyte activationGO:004814320.012
regulation of testosterone biosynthetic processGO:200022420.012
regulation of endopeptidase activityGO:0052548890.012
glucose homeostasisGO:00425931280.012
regulation of organelle organizationGO:00330432890.012
leukocyte differentiationGO:00025213420.012
response to alcoholGO:0097305480.012
detection of stimulusGO:0051606840.012
regulation of hormone secretionGO:0046883880.012
g protein coupled receptor signaling pathwayGO:00071862430.012
circadian rhythmGO:00076231140.012
multicellular organismal homeostasisGO:00488711640.012
terpenoid biosynthetic processGO:001611470.012
t cell differentiationGO:00302171740.012
cellular response to monosaccharide stimulusGO:0071326470.012
response to reactive oxygen speciesGO:0000302560.012
regulation of cellular component biogenesisGO:00440871810.012
neuron apoptotic processGO:00514021420.012
ribonucleoside metabolic processGO:00091192450.012
energy derivation by oxidation of organic compoundsGO:0015980770.012
renal system processGO:0003014480.012
multi organism behaviorGO:0051705620.012
negative regulation of lymphocyte activationGO:0051250910.012
positive regulation of immune effector processGO:00026991070.012
insulin secretionGO:0030073890.012
cellular response to transforming growth factor beta stimulusGO:0071560880.012
regulation of insulin receptor signaling pathwayGO:0046626210.012
protein import into nucleusGO:0006606950.012
response to estrogenGO:0043627240.012
regulation of cell projection organizationGO:00313442060.012
complement activationGO:0006956160.012
protein homooligomerizationGO:0051260430.012
medium chain fatty acid metabolic processGO:005179110.012
regulation of protein serine threonine kinase activityGO:00719001570.012
spermatogenesisGO:00072832840.012
cation homeostasisGO:00550802120.012
myeloid cell differentiationGO:00300992330.012
b cell mediated immunityGO:0019724710.012
ribose phosphate metabolic processGO:00196932910.012
nucleoside catabolic processGO:00091642060.012
regulation of lipid biosynthetic processGO:0046890540.012
l amino acid transportGO:0015807320.012
triglyceride metabolic processGO:0006641510.012
amino acid betaine transportGO:001583830.012
response to starvationGO:0042594650.012
regulation of protein transportGO:00512231630.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
peptide hormone secretionGO:00300721090.012
cellular response to cytokine stimulusGO:00713451890.012
hexose metabolic processGO:0019318980.012
nuclear divisionGO:00002801580.012
negative regulation of cell activationGO:00508661110.011
regulation of gluconeogenesisGO:0006111300.011
regulation of acetylcholine secretion neurotransmissionGO:001405620.011
positive regulation of cellular catabolic processGO:00313311480.011
negative regulation of t cell activationGO:0050868650.011
negative regulation of endopeptidase activityGO:0010951440.011
response to drugGO:0042493750.011
Mouse
nuclear transportGO:00511691390.011
protein importGO:00170381010.011
regulation of leukocyte proliferationGO:00706631210.011
cellular glucose homeostasisGO:0001678520.011
ribonucleoside monophosphate metabolic processGO:0009161800.011
purine ribonucleoside metabolic processGO:00461282410.011
organelle fissionGO:00482851700.011
protein ubiquitinationGO:00165671710.011
synaptic transmissionGO:00072683290.011
gliogenesisGO:00420631410.011
hormone secretionGO:00468791280.011
epidermis developmentGO:00085441870.011
peptidyl lysine modificationGO:0018205770.011
vasoconstrictionGO:0042310270.011
learningGO:0007612980.011
negative regulation of hydrolase activityGO:0051346710.011
male gonad developmentGO:0008584880.011
diterpenoid biosynthetic processGO:001610270.011
positive regulation of proteolysisGO:0045862850.011
c21 steroid hormone biosynthetic processGO:000670030.011
regulation of cellular response to stressGO:00801351590.011
ribonucleotide metabolic processGO:00092592910.011
regulation of b cell mediated immunityGO:0002712370.011
endothelial cell differentiationGO:0045446410.011
rna processingGO:00063961050.011
small gtpase mediated signal transductionGO:0007264970.011
compound eye developmentGO:004874910.011
retinal blood vessel morphogenesisGO:006130430.011
dopamine uptake involved in synaptic transmissionGO:005158340.011
organ regenerationGO:003110020.011
positive regulation of hormone secretionGO:0046887380.011
axonogenesisGO:00074092740.011
negative regulation of endothelial cell migrationGO:001059640.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
organic hydroxy compound transportGO:0015850930.011
nucleoside triphosphate catabolic processGO:00091432050.011
phagocytosisGO:0006909660.011
cell activation involved in immune responseGO:00022631260.011
gland developmentGO:00487323300.011
mrna metabolic processGO:0016071840.011
nuclear importGO:0051170950.011
cellular response to alcoholGO:0097306230.010
epithelial cell developmentGO:00020641590.010
positive regulation of protein kinase b signalingGO:0051897320.010
regulation of vasculature developmentGO:1901342880.010
protein localization to membraneGO:00726571080.010
alpha beta t cell activationGO:0046631910.010
ribonucleotide catabolic processGO:00092612080.010
purine nucleoside triphosphate metabolic processGO:00091442260.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
response to transforming growth factor betaGO:0071559880.010
regulation of cytokine secretionGO:0050707610.010
peptidyl tyrosine phosphorylationGO:00181081430.010
cell matrix adhesionGO:0007160680.010
drug transmembrane transportGO:000685550.010
blood circulationGO:00080151950.010
regulation of immunoglobulin mediated immune responseGO:0002889370.010
interleukin 8 productionGO:003263740.010
retinoic acid biosynthetic processGO:000213870.010

Slco1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.112
inherited metabolic disorderDOID:65500.066
immune system diseaseDOID:291400.025
hematopoietic system diseaseDOID:7400.025
hemolytic anemiaDOID:58300.025
disease of anatomical entityDOID:700.025
anemiaDOID:235500.025
normocytic anemiaDOID:72000.025
hemolytic uremic syndromeDOID:1255400.025
lipid metabolism disorderDOID:314600.023
steroid inherited metabolic disorderDOID:170100.023
nervous system diseaseDOID:86300.020
eye and adnexa diseaseDOID:149200.019
sensory system diseaseDOID:005015500.019
eye diseaseDOID:561400.019
retinal diseaseDOID:567900.010