Mus musculus

125 known processes

Cdc73

cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

(Aliases: BC027756,MGC29274,8430414L16Rik,Hrpt2,C130030P16Rik,MGC36559,C81219)

Cdc73 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
covalent chromatin modificationGO:00165691630.812
Human
chromatin modificationGO:00165681870.754
Human
dna metabolic processGO:00062593030.592
protein modification by small protein conjugation or removalGO:00706472070.563
Human
protein ubiquitinationGO:00165671710.493
Human
regulation of cell cycleGO:00517262810.469
Human
mitotic cell cycleGO:00002781950.395
Human
histone modificationGO:00165701590.385
Human
protein modification by small protein conjugationGO:00324461870.382
Human
cellular response to dna damage stimulusGO:00069742070.375
blastocyst developmentGO:0001824800.304
blastocyst growthGO:0001832230.300
intestinal epithelial structure maintenanceGO:006072940.295
modification dependent protein catabolic processGO:00199411330.273
organelle fissionGO:00482851700.241
negative regulation of mitotic cell cycleGO:0045930580.229
Human
chromatin organizationGO:00063252060.225
Human
negative regulation of protein metabolic processGO:00512482820.210
protein catabolic processGO:00301632210.208
cellular protein catabolic processGO:00442571550.208
nuclear dna replicationGO:003326030.181
negative regulation of protein modification processGO:00314001630.175
proteolysis involved in cellular protein catabolic processGO:00516031470.164
nuclear divisionGO:00002801580.155
macromolecule catabolic processGO:00090572810.137
ubiquitin dependent protein catabolic processGO:00065111290.137
negative regulation of cellular protein metabolic processGO:00322692470.133
modification dependent macromolecule catabolic processGO:00436321330.132
peptidyl amino acid modificationGO:00181933360.128
mitotic nuclear divisionGO:0007067480.125
dna replicationGO:0006260520.122
apoptotic signaling pathwayGO:00971903060.118
proteasomal protein catabolic processGO:0010498980.115
regionalizationGO:00030023370.108
bmp signaling pathwayGO:0030509930.107
macromolecule methylationGO:00434141200.097
regulation of cell cycle processGO:00105641600.094
Human
nucleoside triphosphate metabolic processGO:00091412300.093
cell adhesionGO:00071553290.092
formation of primary germ layerGO:0001704770.092
regulation of chromosome organizationGO:0033044830.092
multicellular organism growthGO:00352641610.090
histone h2a ubiquitinationGO:003352230.078
chromosome segregationGO:0007059480.075
myeloid cell differentiationGO:00300992330.075
Human Zebrafish
neuron projection guidanceGO:00974851410.071
maintenance of locationGO:0051235890.071
dendritic spine developmentGO:0060996300.070
wnt signaling pathwayGO:00160551880.070
Human Fly
intracellular receptor signaling pathwayGO:0030522740.066
compound eye developmentGO:004874910.064
Fly
cell fate commitmentGO:00451652100.062
regulation of cell cycle phase transitionGO:1901987770.061
Human
negative regulation of cell cycle phase transitionGO:1901988480.061
Human
establishment of mitochondrion localizationGO:005165440.059
development of primary sexual characteristicsGO:00451371430.058
protein methylationGO:0006479810.058
regulation of mitotic cell cycle phase transitionGO:1901990730.058
Human
response to oxidative stressGO:00069791230.058
neural tube developmentGO:00219151600.058
germ cell developmentGO:00072811850.057
organelle localizationGO:00516401790.057
cellular amine metabolic processGO:0044106440.056
regulation of histone modificationGO:0031056560.055
peptidyl lysine modificationGO:0018205770.054
protein alkylationGO:0008213810.053
gonad developmentGO:00084061410.053
epithelial structure maintenanceGO:001066990.052
regulation of organelle organizationGO:00330432890.051
dendrite developmentGO:00163581150.051
regulation of protein ubiquitinationGO:0031396520.050
regulation of apoptotic signaling pathwayGO:20012331970.050
amine metabolic processGO:0009308450.050
developmental maturationGO:00217001930.049
regulation of cellular amino acid metabolic processGO:000652150.048
axonogenesisGO:00074092740.047
pallium developmentGO:00215431200.047
plus end directed organelle transport along microtubuleGO:007238620.047
regulation of chromatin modificationGO:1903308570.045
methylationGO:00322591340.044
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.044
negative regulation of nervous system developmentGO:00519611560.043
blastocyst formationGO:0001825330.043
histone ubiquitinationGO:0016574100.043
Human
ribonucleotide metabolic processGO:00092592910.043
positive regulation of cell activationGO:00508671580.042
regulation of mitotic cell cycleGO:00073461260.041
Human
sequestering of calcium ionGO:0051208180.040
negative regulation of hydrolase activityGO:0051346710.040
rhythmic processGO:00485111740.039
cellular ketone metabolic processGO:0042180840.039
homeostasis of number of cellsGO:00488722100.039
Zebrafish
gene silencingGO:0016458380.039
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.039
regulation of cellular component biogenesisGO:00440871810.038
purine nucleotide metabolic processGO:00061633020.038
digestive tract morphogenesisGO:00485461470.038
fertilizationGO:00095661270.038
regulation of lymphocyte activationGO:00512492400.038
regulation of neural precursor cell proliferationGO:2000177700.037
ribose phosphate metabolic processGO:00196932910.037
regulation of proteolysisGO:00301621640.036
t cell differentiationGO:00302171740.036
regulation of cellular ketone metabolic processGO:0010565660.036
muscle cell differentiationGO:00426922610.036
gastrulationGO:00073691160.036
mrna processingGO:0006397630.036
Human
cellular macromolecule catabolic processGO:00442652060.036
dna damage checkpointGO:0000077260.035
digestive tract developmentGO:00485651900.035
gland developmentGO:00487323300.035
negative regulation of immune system processGO:00026832090.035
Human
cellular response to growth factor stimulusGO:00713631970.034
regulation of cell activationGO:00508652890.033
anatomical structure homeostasisGO:00602491450.033
striated muscle tissue developmentGO:00147062930.033
negative regulation of cell cycleGO:00457861230.033
Human
digestionGO:0007586400.033
positive regulation of programmed cell deathGO:00430682180.033
positive regulation of cell cycleGO:0045787920.032
female gamete generationGO:0007292740.032
chemotaxisGO:00069352470.032
negative regulation of cellular amine metabolic processGO:003323910.032
multi multicellular organism processGO:00447061090.032
forebrain developmentGO:00309003020.032
multicellular organismal homeostasisGO:00488711640.032
protein acylationGO:0043543640.032
positive regulation of cell deathGO:00109422240.032
cation transportGO:00068123990.031
protein maturationGO:00516041760.031
synaptic transmissionGO:00072683290.031
purine ribonucleotide catabolic processGO:00091542080.031
circadian rhythmGO:00076231140.030
regulation of t cell activationGO:00508631700.030
aromatic compound catabolic processGO:00194392860.029
regulation of cellular catabolic processGO:00313292420.029
negative regulation of molecular functionGO:00440922580.029
negative regulation of cell cycle processGO:0010948690.028
Human
purine ribonucleoside catabolic processGO:00461302050.028
stem cell proliferationGO:00720891170.028
cytoplasmic transportGO:00164822340.028
organic cyclic compound catabolic processGO:19013612950.028
canonical wnt signaling pathwayGO:00600701300.028
regulation of transcription by chromatin organizationGO:003440100.028
transcription initiation from rna polymerase ii promoterGO:000636780.027
purine nucleoside catabolic processGO:00061522050.027
macromolecule deacylationGO:0098732370.027
regulation of ion transportGO:00432692150.027
cell cycle checkpointGO:0000075470.027
protein processingGO:00164851630.027
histone monoubiquitinationGO:001039030.027
Human
locomotory behaviorGO:00076261950.027
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.027
hindbrain developmentGO:00309021280.027
signal transduction by p53 class mediatorGO:0072331510.027
oocyte axis specificationGO:000730920.027
oocyte constructionGO:000730820.027
purine containing compound catabolic processGO:00725232130.027
negative regulation of cell proliferationGO:00082852960.026
Human
dna integrity checkpointGO:0031570280.026
spermatogenesisGO:00072832840.026
t cell activationGO:00421102890.026
regulation of stem cell proliferationGO:0072091780.026
cell divisionGO:00513011200.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
skeletal muscle organ developmentGO:00605381630.026
cell cycle switching mitotic to meiotic cell cycleGO:005172810.025
regulation of protein modification by small protein conjugation or removalGO:1903320570.025
rna processingGO:00063961050.025
Human
lymphocyte proliferationGO:00466511640.025
purine ribonucleotide metabolic processGO:00091502900.025
rna 3 end processingGO:0031123200.025
Human
regulation of leukocyte proliferationGO:00706631210.025
microtubule based processGO:00070172360.025
ossificationGO:00015032160.024
posttranscriptional regulation of gene expressionGO:00106081550.024
Human
cellular amino acid metabolic processGO:00065201030.024
muscle tissue developmentGO:00605373080.024
respiratory tube developmentGO:00303231670.024
hematopoietic progenitor cell differentiationGO:00022441430.024
dna templated transcription initiationGO:0006352130.024
neural precursor cell proliferationGO:00613511210.024
response to organic cyclic compoundGO:00140701980.024
response to inorganic substanceGO:0010035960.023
positive regulation of growthGO:00459271040.023
stem cell differentiationGO:00488632680.023
establishment of organelle localizationGO:00516561220.023
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.023
regulation of cellular amine metabolic processGO:0033238200.022
leukocyte differentiationGO:00025213420.022
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.022
regulation of protein maturationGO:1903317960.022
b cell activationGO:00421131610.022
cell growthGO:00160491300.022
intracellular protein transportGO:00068862040.022
sensory perceptionGO:00076002450.022
small gtpase mediated signal transductionGO:0007264970.021
negative regulation of proteolysisGO:0045861740.021
male meiosis iGO:0007141160.021
regulation of mesenchymal cell proliferationGO:0010464370.021
microtubule based movementGO:0007018840.021
cell type specific apoptotic processGO:00972852680.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
visceral motor neuron differentiationGO:002152430.020
regulation of protein complex assemblyGO:0043254830.020
response to growth factorGO:00708481980.020
negative regulation of dna replicationGO:000815640.020
positive regulation of immature t cell proliferationGO:003309140.020
regulation of leukocyte differentiationGO:19021051590.020
negative regulation of cellular component organizationGO:00511291940.020
negative regulation of protein processingGO:0010955790.020
inorganic ion transmembrane transportGO:00986602340.019
purine containing compound metabolic processGO:00725213110.019
carbohydrate derivative catabolic processGO:19011362310.019
cellular nitrogen compound catabolic processGO:00442702800.019
lymphocyte differentiationGO:00300982420.019
positive regulation of cellular amine metabolic processGO:003324050.019
negative regulation of apoptotic signaling pathwayGO:20012341040.019
metal ion homeostasisGO:00550651890.019
divalent inorganic cation homeostasisGO:00725071380.019
circulatory system processGO:00030131970.019
nucleoside metabolic processGO:00091162460.019
cellular lipid metabolic processGO:00442553230.019
cellular response to cytokine stimulusGO:00713451890.019
negative regulation of phosphate metabolic processGO:00459361840.019
membrane organizationGO:00610242450.019
mitochondrion transport along microtubuleGO:004749730.019
digestive system developmentGO:00551232000.019
carbohydrate metabolic processGO:00059752300.018
endodermal cell fate specificationGO:000171440.018
intracellular steroid hormone receptor signaling pathwayGO:0030518290.018
tissue homeostasisGO:00018941150.018
regulation of protein processingGO:0070613960.018
single organismal cell cell adhesionGO:00163371310.018
cellular calcium ion homeostasisGO:00068741190.018
regulation of t cell differentiationGO:0045580830.018
axon guidanceGO:00074111410.018
trophectodermal cell differentiationGO:0001829210.018
skeletal system morphogenesisGO:00487052030.018
cellularizationGO:000734910.018
nucleotide metabolic processGO:00091173320.017
histone acetylationGO:0016573410.017
chromatin silencingGO:0006342150.017
regulation of canonical wnt signaling pathwayGO:0060828820.017
jak stat cascadeGO:0007259420.017
cellular response to oxidative stressGO:0034599760.017
cellular chemical homeostasisGO:00550822150.017
camera type eye developmentGO:00430102660.017
transcription from rna polymerase i promoterGO:0006360130.017
organonitrogen compound catabolic processGO:19015652640.017
glucose homeostasisGO:00425931280.017
ribonucleoside monophosphate metabolic processGO:0009161800.017
cellular response to organonitrogen compoundGO:00714171450.017
respiratory system developmentGO:00605411900.016
positive regulation of organelle organizationGO:00106381280.016
cellular response to acid chemicalGO:0071229680.016
developmental growth involved in morphogenesisGO:00605601380.016
tube formationGO:00351481400.016
cellular homeostasisGO:00197252400.016
calcium ion homeostasisGO:00550741270.016
positive regulation of nervous system developmentGO:00519622210.016
defecationGO:003042110.016
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.016
nucleoside phosphate metabolic processGO:00067533380.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
meiotic cell cycleGO:00513211220.015
regulation of ossificationGO:00302781120.015
regulation of b cell activationGO:0050864810.015
negative regulation of phosphorus metabolic processGO:00105631840.015
positive regulation of apoptotic processGO:00430652170.015
leukocyte proliferationGO:00706611720.015
regulation of cellular protein catabolic processGO:1903362610.015
response to radiationGO:00093141650.015
multi organism behaviorGO:0051705620.015
regulation of lymphocyte proliferationGO:00506701170.015
neuron migrationGO:00017641220.015
atp catabolic processGO:0006200550.015
glycerolipid metabolic processGO:00464861220.015
negative regulation of phosphorylationGO:00423261660.015
ribonucleotide catabolic processGO:00092612080.015
plasma membrane organizationGO:0007009900.015
nucleoside phosphate catabolic processGO:19012922220.015
leukocyte homeostasisGO:0001776790.014
glycosyl compound metabolic processGO:19016572460.014
appendage developmentGO:00487361660.014
Fly
defense response to other organismGO:00985421970.014
adaptive immune responseGO:00022501550.014
positive regulation of b cell activationGO:0050871490.014
positive regulation of stem cell proliferationGO:2000648590.014
cell maturationGO:00484691270.014
epithelial cell developmentGO:00020641590.014
embryonic epithelial tube formationGO:00018381300.014
lipid localizationGO:00108761260.014
lateral inhibitionGO:004633110.014
response to organonitrogen compoundGO:00102432460.014
cellular response to lipidGO:00713961450.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.014
purine ribonucleoside triphosphate catabolic processGO:00092071990.014
histone lysine methylationGO:0034968500.014
embryonic placenta developmentGO:0001892980.013
nucleotide catabolic processGO:00091662170.013
positive regulation of t cell differentiationGO:0045582520.013
female gonad developmentGO:0008585710.013
striated muscle cell developmentGO:00550021250.013
negative regulation of peptidase activityGO:0010466460.013
cation homeostasisGO:00550802120.013
mesenchymal cell proliferationGO:0010463440.013
oogenesisGO:0048477560.013
negative regulation of protein maturationGO:1903318790.013
mitotic cell cycle checkpointGO:0007093310.013
negative regulation of gene expression epigeneticGO:0045814150.013
inorganic cation transmembrane transportGO:00986622070.013
protein localization to plasma membraneGO:0072659570.013
tissue migrationGO:0090130680.013
skeletal system developmentGO:00015013560.013
regulation of secretionGO:00510462740.013
smoothened signaling pathwayGO:00072241050.013
Fly
fat cell differentiationGO:00454441600.013
protein deacetylationGO:0006476320.013
regulation of lymphocyte differentiationGO:00456191070.013
negative regulation of mesenchymal cell proliferationGO:007220130.013
negative regulation of synapse assemblyGO:005196430.013
detection of stimulusGO:0051606840.013
single organism cell adhesionGO:00986021560.013
histone methylationGO:0016571710.013
regulation of chromatin organizationGO:1902275570.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.013
rna interferenceGO:001624620.013
cytoskeleton dependent intracellular transportGO:0030705500.013
endodermal cell differentiationGO:0035987140.012
calcium ion transportGO:00068161590.012
dna alkylationGO:0006305430.012
telencephalon developmentGO:00215371860.012
purine ribonucleoside metabolic processGO:00461282410.012
segmentationGO:0035282930.012
regulation of establishment of protein localizationGO:00702011810.012
hexose metabolic processGO:0019318980.012
regulation of cell migrationGO:00303342190.012
positive regulation of cell developmentGO:00107202370.012
adipose tissue developmentGO:0060612250.012
defense response to bacteriumGO:00427421190.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
microtubule polymerization or depolymerizationGO:0031109260.012
regulation of t cell proliferationGO:0042129920.012
positive regulation of histone modificationGO:0031058280.012
nucleoside catabolic processGO:00091642060.012
wound healingGO:00420601570.012
response to hydrogen peroxideGO:0042542320.012
internal protein amino acid acetylationGO:0006475420.012
regulation of peptidase activityGO:0052547960.012
nucleoside monophosphate metabolic processGO:0009123850.012
glycosyl compound catabolic processGO:19016582060.012
protein localization to membraneGO:00726571080.011
purine nucleotide catabolic processGO:00061952110.011
organophosphate catabolic processGO:00464342320.011
divalent inorganic cation transportGO:00725111780.011
b cell proliferationGO:0042100530.011
chromatin remodelingGO:0006338320.011
negative regulation of endopeptidase activityGO:0010951440.011
stem cell maintenanceGO:00198271300.011
protein autophosphorylationGO:0046777610.011
organelle assemblyGO:00709251770.011
purine nucleoside triphosphate catabolic processGO:00091462030.011
regulation of genetic imprintingGO:200065350.011
endocytosisGO:00068971680.011
central nervous system neuron differentiationGO:00219531620.011
mitotic cell cycle processGO:19030471590.011
Human
somitogenesisGO:0001756690.011
cation transmembrane transportGO:00986552660.011
glycoprotein metabolic processGO:00091001160.011
organic anion transportGO:00157111370.011
morphogenesis of a branching epitheliumGO:00611381930.011
regulation of cell projection organizationGO:00313442060.011
positive regulation of t cell activationGO:00508701010.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
ncrna processingGO:0034470260.011
intrinsic apoptotic signaling pathwayGO:00971931320.011
positive regulation of macroautophagyGO:001623930.011
positive regulation of mitotic metaphase anaphase transitionGO:004584220.011
positive regulation of t cell proliferationGO:0042102520.011
endocrine system developmentGO:0035270980.011
regulation of neuron projection developmentGO:00109751690.011
negative regulation of translationGO:0017148220.011
cellular response to fibroblast growth factor stimulusGO:0044344470.011
regulation of protein transportGO:00512231630.011
response to acid chemicalGO:00011011110.010
transcription elongation from rna polymerase ii promoterGO:000636890.010
Human Zebrafish
regulation of protein kinase b signalingGO:0051896560.010
regulation of cellular response to stressGO:00801351590.010
regulation of cell divisionGO:0051302760.010
lens fiber cell apoptotic processGO:199008640.010
positive regulation of lymphocyte differentiationGO:0045621610.010
limbic system developmentGO:0021761720.010
reproductive behaviorGO:0019098320.010
cell cycle switchingGO:006018410.010
regulation of voltage gated calcium channel activityGO:190138540.010
response to lipopolysaccharideGO:00324961280.010
cell agingGO:0007569350.010
atp metabolic processGO:0046034750.010
dna modificationGO:0006304500.010
ribonucleoside catabolic processGO:00424542060.010
golgi vesicle transportGO:0048193300.010
regulation of wnt signaling pathwayGO:00301111230.010
Human
regulation of b cell proliferationGO:0030888390.010

Cdc73 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.112
Human
organ system cancerDOID:005068600.112
Human
disease of cellular proliferationDOID:1456600.112
Human
disease of anatomical entityDOID:700.038
Human
nervous system diseaseDOID:86300.038
central nervous system diseaseDOID:33100.022
neurodegenerative diseaseDOID:128900.022