IMP: Integrative Multi-species Prediction

Mus musculus

22 known processes

Anp32b

acidic (leucine-rich) nuclear phosphoprotein 32 family, member B

(Aliases: MGC103080,PHAPI2a,Ssp29,PAL31,2410015B15Rik)

Entrez: 67628
Ensembl: ENSMUSG00000028333
UniProtKB: Q9EST5

Process Predictions
Disease Predictions

Anp32b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromatin organization	GO:0006325	206	0.703	Human
translation	GO:0006412	93	0.601
chromatin modification	GO:0016568	187	0.262
negative regulation of cellular protein metabolic process	GO:0032269	247	0.254
development of primary sexual characteristics	GO:0045137	143	0.234
gonad development	GO:0008406	141	0.232
negative regulation of molecular function	GO:0044092	258	0.225	Mouse
oocyte construction	GO:0007308	2	0.220
transcription coupled nucleotide excision repair	GO:0006283	2	0.201
dna metabolic process	GO:0006259	303	0.183	Human
nuclear transcribed mrna catabolic process nonsense mediated decay	GO:0000184	1	0.175
mitotic cell cycle process	GO:1903047	159	0.173	Rat
dna repair	GO:0006281	107	0.156
nitrogen compound transport	GO:0071705	271	0.146
body morphogenesis	GO:0010171	45	0.146
positive regulation of rna splicing	GO:0033120	12	0.125
regulation of cellular component biogenesis	GO:0044087	181	0.115
microtubule based process	GO:0007017	236	0.113
regulation of mrna metabolic process	GO:1903311	43	0.105
rna localization	GO:0006403	23	0.105
oocyte anterior posterior axis specification	GO:0007314	2	0.104
mrna transport	GO:0051028	13	0.100
heterochromatin organization	GO:0070828	4	0.094
nuclear transport	GO:0051169	139	0.092	Human
cellular macromolecule catabolic process	GO:0044265	206	0.090
oocyte differentiation	GO:0009994	35	0.089
posttranscriptional regulation of gene expression	GO:0010608	155	0.088
cellular response to dna damage stimulus	GO:0006974	207	0.082
rna transport	GO:0050658	18	0.081
nucleic acid transport	GO:0050657	18	0.077
germ cell development	GO:0007281	185	0.075
macromolecule catabolic process	GO:0009057	281	0.072
rna processing	GO:0006396	105	0.071
endocytosis	GO:0006897	168	0.071
organelle fission	GO:0048285	170	0.070
mitotic cell cycle	GO:0000278	195	0.069	Rat
cellular amino acid metabolic process	GO:0006520	103	0.067
cytoplasmic transport	GO:0016482	234	0.067	Human
positive regulation of mrna metabolic process	GO:1903313	17	0.064
nucleocytoplasmic transport	GO:0006913	139	0.063	Human
purine nucleoside catabolic process	GO:0006152	205	0.062
protein localization to nucleus	GO:0034504	121	0.061
cellular response to cytokine stimulus	GO:0071345	189	0.061
small gtpase mediated signal transduction	GO:0007264	97	0.061
intracellular mrna localization	GO:0008298	4	0.060
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.060
cytoplasmic microtubule organization	GO:0031122	14	0.058
negative regulation of rna splicing	GO:0033119	12	0.058
female gamete generation	GO:0007292	74	0.058
axon guidance	GO:0007411	141	0.058
nuclear export	GO:0051168	34	0.054	Human
regulation of translation	GO:0006417	71	0.054
ras protein signal transduction	GO:0007265	77	0.053
mrna processing	GO:0006397	63	0.053
regulation of purine nucleotide catabolic process	GO:0033121	122	0.052
negative regulation of dna templated transcription termination	GO:0060567	1	0.052
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.052
negative regulation of protein metabolic process	GO:0051248	282	0.051
ossification	GO:0001503	216	0.051
circulatory system process	GO:0003013	197	0.051
ribonucleoside catabolic process	GO:0042454	206	0.049
embryonic organ morphogenesis	GO:0048562	276	0.049
amine metabolic process	GO:0009308	45	0.049
response to organic cyclic compound	GO:0014070	198	0.049
positive regulation of mrna processing	GO:0050685	16	0.047
regulation of mrna processing	GO:0050684	41	0.047
mitotic nuclear division	GO:0007067	48	0.047
regulation of mrna splicing via spliceosome	GO:0048024	32	0.046
regulation of cell cycle phase transition	GO:1901987	77	0.045	Rat
nuclear import	GO:0051170	95	0.045
regulation of mitotic cell cycle	GO:0007346	126	0.045	Rat
histone modification	GO:0016570	159	0.044
aromatic compound catabolic process	GO:0019439	286	0.044
mrna catabolic process	GO:0006402	22	0.043
heterocycle catabolic process	GO:0046700	280	0.042
protein import into nucleus	GO:0006606	95	0.042
regulation of mrna stability	GO:0043488	23	0.042
macromolecule methylation	GO:0043414	120	0.041
multicellular organism growth	GO:0035264	161	0.040
purine ribonucleoside metabolic process	GO:0046128	241	0.040
nucleoside catabolic process	GO:0009164	206	0.038
establishment of organelle localization	GO:0051656	122	0.038
nucleobase containing compound transport	GO:0015931	27	0.038
nucleotide metabolic process	GO:0009117	332	0.038
chromatin assembly or disassembly	GO:0006333	16	0.036	Human
receptor mediated endocytosis	GO:0006898	51	0.036
intracellular protein transport	GO:0006886	204	0.035	Human
regulation of ras protein signal transduction	GO:0046578	114	0.035
regulation of polyamine transmembrane transport	GO:1902267	5	0.034
oogenesis	GO:0048477	56	0.034
oxidation reduction process	GO:0055114	342	0.033
regulation of rna splicing	GO:0043484	37	0.033
dna templated transcription elongation	GO:0006354	13	0.033
protein localization to organelle	GO:0033365	185	0.032
chemotaxis	GO:0006935	247	0.032
cellular amine metabolic process	GO:0044106	44	0.032
regulation of organelle organization	GO:0033043	289	0.032
cell type specific apoptotic process	GO:0097285	268	0.032
positive regulation of nucleocytoplasmic transport	GO:0046824	30	0.032	Human
hormone secretion	GO:0046879	128	0.032
nuclear transcribed mrna catabolic process	GO:0000956	16	0.030
respiratory system development	GO:0060541	190	0.030
nucleobase containing small molecule metabolic process	GO:0055086	352	0.029
regulation of cellular catabolic process	GO:0031329	242	0.029
cellular nitrogen compound catabolic process	GO:0044270	280	0.029
protein targeting	GO:0006605	143	0.029
circadian rhythm	GO:0007623	114	0.029
oocyte axis specification	GO:0007309	2	0.029
pole plasm assembly	GO:0007315	2	0.029
positive regulation of cellular component biogenesis	GO:0044089	94	0.028
methylation	GO:0032259	134	0.028
phagocytosis	GO:0006909	66	0.028
myeloid cell differentiation	GO:0030099	233	0.028
segmentation	GO:0035282	93	0.028
positive regulation of mrna splicing via spliceosome	GO:0048026	11	0.028
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.028	Rat
dna modification	GO:0006304	50	0.028
blood circulation	GO:0008015	195	0.027
regulation of cellular component size	GO:0032535	121	0.027
lung development	GO:0030324	164	0.027
negative regulation of phosphorus metabolic process	GO:0010563	184	0.027
microtubule cytoskeleton organization	GO:0000226	157	0.026
protein import	GO:0017038	101	0.026
leukocyte migration	GO:0050900	124	0.026
negative regulation of purine nucleotide metabolic process	GO:1900543	16	0.025
cellular response to hormone stimulus	GO:0032870	150	0.025
cell recognition	GO:0008037	83	0.025
positive regulation of myeloid cell differentiation	GO:0045639	43	0.025
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.025
pore complex assembly	GO:0046931	3	0.025
negative regulation of ras protein signal transduction	GO:0046580	18	0.024
regulation of multi organism process	GO:0043900	111	0.024
regulation of nucleotide metabolic process	GO:0006140	169	0.024
single organism nuclear import	GO:1902593	95	0.024
positive regulation of organelle organization	GO:0010638	128	0.024
regulation of purine nucleotide metabolic process	GO:1900542	169	0.024
hematopoietic progenitor cell differentiation	GO:0002244	143	0.024
double strand break repair	GO:0006302	48	0.024
rhythmic process	GO:0048511	174	0.024
negative regulation of mrna splicing via spliceosome	GO:0048025	12	0.023
negative regulation of phosphate metabolic process	GO:0045936	184	0.023
regulation of hydrolase activity	GO:0051336	246	0.023	Human
regulation of cellular amino acid metabolic process	GO:0006521	5	0.023
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.023
actin cytoskeleton organization	GO:0030036	220	0.023
negative regulation of nucleotide metabolic process	GO:0045980	16	0.022
positive regulation of growth	GO:0045927	104	0.022
leukocyte differentiation	GO:0002521	342	0.022
forebrain development	GO:0030900	302	0.022
neuron projection guidance	GO:0097485	141	0.022
organophosphate catabolic process	GO:0046434	232	0.022
microtubule cytoskeleton organization involved in mitosis	GO:1902850	4	0.021
regulation of cell cycle process	GO:0010564	160	0.021	Rat
response to inorganic substance	GO:0010035	96	0.021
negative regulation of intracellular signal transduction	GO:1902532	167	0.021
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.021
purine nucleotide catabolic process	GO:0006195	211	0.021
regulation of intracellular protein transport	GO:0033157	82	0.021	Human
regulation of cell projection organization	GO:0031344	206	0.021
epithelial cell proliferation	GO:0050673	174	0.021
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.020
mesenchymal cell development	GO:0014031	93	0.020
innate immune response	GO:0045087	157	0.020
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.020
peptidyl amino acid modification	GO:0018193	336	0.019
cellular protein complex disassembly	GO:0043624	36	0.019
organelle localization	GO:0051640	179	0.019
protein complex disassembly	GO:0043241	40	0.018
placenta development	GO:0001890	140	0.018
generation of precursor metabolites and energy	GO:0006091	103	0.018
positive regulation of cellular amine metabolic process	GO:0033240	5	0.018
regulation of protein kinase activity	GO:0045859	232	0.018
poly a mrna export from nucleus	GO:0016973	4	0.018
cell cell recognition	GO:0009988	44	0.018
regulation of rna stability	GO:0043487	26	0.018
dna dealkylation	GO:0035510	11	0.018
cell chemotaxis	GO:0060326	81	0.018
negative regulation of nucleotide catabolic process	GO:0030812	9	0.018
cell substrate junction assembly	GO:0007044	24	0.018
regulation of binding	GO:0051098	111	0.017
angiogenesis	GO:0001525	201	0.017
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.017
mrna metabolic process	GO:0016071	84	0.017
response to oxidative stress	GO:0006979	123	0.017
mesenchymal cell differentiation	GO:0048762	107	0.017
cell maturation	GO:0048469	127	0.017
negative regulation of neuron apoptotic process	GO:0043524	92	0.017
genitalia development	GO:0048806	37	0.017
regulation of cell cycle g2 m phase transition	GO:1902749	10	0.016
regulation of cytoskeleton organization	GO:0051493	122	0.016
regulation of hormone levels	GO:0010817	211	0.016
regulation of intracellular transport	GO:0032386	159	0.016	Human
regulation of protein import into nucleus	GO:0042306	52	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
negative regulation of translation	GO:0017148	22	0.016
developmental growth involved in morphogenesis	GO:0060560	138	0.016
nucleoside phosphate metabolic process	GO:0006753	338	0.016
positive regulation of dna templated transcription elongation	GO:0032786	2	0.016
diencephalon development	GO:0021536	63	0.016
protein methylation	GO:0006479	81	0.016
respiratory tube development	GO:0030323	167	0.016
neuron death	GO:0070997	154	0.016
maternal process involved in female pregnancy	GO:0060135	32	0.016
rna splicing	GO:0008380	54	0.016
sensory perception	GO:0007600	245	0.016
protein maturation	GO:0051604	176	0.015	Human
nucleoside metabolic process	GO:0009116	246	0.015
cell growth	GO:0016049	130	0.015
regulation of nucleotide catabolic process	GO:0030811	122	0.015
regulation of protein complex assembly	GO:0043254	83	0.015
regulation of cell activation	GO:0050865	289	0.015
epithelial tube morphogenesis	GO:0060562	303	0.015
muscle system process	GO:0003012	141	0.015
ribonucleotide metabolic process	GO:0009259	291	0.015
regulation of leukocyte differentiation	GO:1902105	159	0.015
blood vessel morphogenesis	GO:0048514	285	0.015
regulation of cell cycle	GO:0051726	281	0.015	Rat
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.014
regulation of hormone secretion	GO:0046883	88	0.014
movement in environment of other organism involved in symbiotic interaction	GO:0052192	15	0.014
camera type eye development	GO:0043010	266	0.014
ribonucleoside metabolic process	GO:0009119	245	0.014
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.014
regulation of protein transport	GO:0051223	163	0.014	Human
positive regulation of intracellular transport	GO:0032388	70	0.014	Human
dna replication	GO:0006260	52	0.014
regulation of embryonic development	GO:0045995	71	0.014
regulation of protein stability	GO:0031647	52	0.014
cellular ketone metabolic process	GO:0042180	84	0.014
gene silencing	GO:0016458	38	0.014
guanosine containing compound catabolic process	GO:1901069	144	0.013
cellular polysaccharide metabolic process	GO:0044264	38	0.013
regulation of nucleoside metabolic process	GO:0009118	130	0.013
maternal placenta development	GO:0001893	20	0.013
axonogenesis	GO:0007409	274	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
establishment of protein localization to organelle	GO:0072594	118	0.013
regulation of protein localization	GO:0032880	231	0.013	Human
positive regulation of cytoplasmic transport	GO:1903651	40	0.013	Human
internal peptidyl lysine acetylation	GO:0018393	42	0.013
rac protein signal transduction	GO:0016601	13	0.013
negative regulation of atpase activity	GO:0032780	2	0.013
ion transmembrane transport	GO:0034220	361	0.013
spindle assembly involved in mitosis	GO:0090307	4	0.013
establishment of rna localization	GO:0051236	18	0.013
negative regulation of phosphorylation	GO:0042326	166	0.012
rna catabolic process	GO:0006401	29	0.012
regulation of lymphocyte activation	GO:0051249	240	0.012
positive regulation of programmed cell death	GO:0043068	218	0.012	Human
branching morphogenesis of an epithelial tube	GO:0048754	159	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
nuclear division	GO:0000280	158	0.012
regulation of cellular amine metabolic process	GO:0033238	20	0.012
stem cell differentiation	GO:0048863	268	0.012
male gamete generation	GO:0048232	285	0.012
regulation of nucleocytoplasmic transport	GO:0046822	73	0.012	Human
cognition	GO:0050890	149	0.012
regulation of cellular ketone metabolic process	GO:0010565	66	0.012
regulation of myeloid cell differentiation	GO:0045637	96	0.012
positive regulation of nucleotide catabolic process	GO:0030813	88	0.011
ribonucleotide catabolic process	GO:0009261	208	0.011
regulation of circadian rhythm	GO:0042752	58	0.011
regulation of gtp catabolic process	GO:0033124	113	0.011
response to temperature stimulus	GO:0009266	55	0.011
cellular protein complex assembly	GO:0043623	116	0.011
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.011
protein ubiquitination	GO:0016567	171	0.011
mrna splicing via spliceosome	GO:0000398	43	0.011
germ cell proliferation	GO:0036093	7	0.011
muscle tissue development	GO:0060537	308	0.011
negative regulation of purine nucleotide catabolic process	GO:0033122	9	0.011
rna splicing via transesterification reactions	GO:0000375	43	0.011
mesenchyme development	GO:0060485	152	0.011
lymphocyte proliferation	GO:0046651	164	0.011
learning	GO:0007612	98	0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.011
positive regulation of transcription from rna polymerase i promoter	GO:0045943	3	0.011
determination of heart left right asymmetry	GO:0061371	48	0.011
mrna export from nucleus	GO:0006406	11	0.011
regulation of wnt signaling pathway	GO:0030111	123	0.011
fertilization	GO:0009566	127	0.011
positive regulation of cytoskeleton organization	GO:0051495	49	0.011
negative regulation of cell proliferation	GO:0008285	296	0.011
developmental cell growth	GO:0048588	84	0.011
purine ribonucleotide catabolic process	GO:0009154	208	0.011
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.011
response to heat	GO:0009408	27	0.011
dna packaging	GO:0006323	30	0.011	Human
cardiac muscle contraction	GO:0060048	32	0.011
purine ribonucleoside catabolic process	GO:0046130	205	0.011
organelle assembly	GO:0070925	177	0.010
spermatogenesis	GO:0007283	284	0.010
learning or memory	GO:0007611	148	0.010
regulation of epithelial cell proliferation	GO:0050678	141	0.010
negative regulation of neuron death	GO:1901215	98	0.010
response to growth factor	GO:0070848	198	0.010
gland development	GO:0048732	330	0.010
purine containing compound biosynthetic process	GO:0072522	70	0.010

Anp32b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.047
colorectal cancer	DOID:9256	0.047
organ system cancer	DOID:0050686	0.047
large intestine cancer	DOID:5672	0.047
cancer	DOID:162	0.047
gastrointestinal system cancer	DOID:3119	0.047
intestinal cancer	DOID:10155	0.047
colon cancer	DOID:219	0.047
nervous system disease	DOID:863	0.013
disease of anatomical entity	DOID:7	0.013

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