Mus musculus

0 known processes

Cdk12

cyclin-dependent kinase 12

(Aliases: AI646528,Crkrs,Pksc,MGC141525,1810022J16Rik,Crk7,D11Ertd752e)

Cdk12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatogenesisGO:00072832840.071
regulation of cellular ketone metabolic processGO:0010565660.065
regulation of cell cycle processGO:00105641600.059
male gamete generationGO:00482322850.059
cellular macromolecule catabolic processGO:00442652060.057
chromatin organizationGO:00063252060.055
modification dependent macromolecule catabolic processGO:00436321330.050
regulation of cell cycleGO:00517262810.049
regulation of cellular amino acid metabolic processGO:000652150.047
germ cell developmentGO:00072811850.046
amine metabolic processGO:0009308450.045
covalent chromatin modificationGO:00165691630.045
macromolecule catabolic processGO:00090572810.044
regulation of organelle organizationGO:00330432890.044
cellular amino acid metabolic processGO:00065201030.042
protein modification by small protein conjugation or removalGO:00706472070.041
protein ubiquitinationGO:00165671710.041
cellular ketone metabolic processGO:0042180840.041
regulation of transferase activityGO:00513382630.041
Human
nuclear divisionGO:00002801580.035
multicellular organism growthGO:00352641610.035
gland developmentGO:00487323300.034
cellular nitrogen compound catabolic processGO:00442702800.033
proteolysis involved in cellular protein catabolic processGO:00516031470.033
heterocycle catabolic processGO:00467002800.032
regulation of kinase activityGO:00435492490.032
Human
negative regulation of cellular protein metabolic processGO:00322692470.031
mrna metabolic processGO:0016071840.031
Mouse
rna catabolic processGO:0006401290.031
histone modificationGO:00165701590.030
dna metabolic processGO:00062593030.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
appendage morphogenesisGO:00351071490.029
chromatin modificationGO:00165681870.029
protein modification by small protein conjugationGO:00324461870.029
aromatic compound catabolic processGO:00194392860.029
regulation of neuron differentiationGO:00456642810.029
myeloid cell differentiationGO:00300992330.028
negative regulation of cellular component organizationGO:00511291940.028
positive regulation of protein modification processGO:00314012990.028
organelle fissionGO:00482851700.028
positive regulation of transferase activityGO:00513471670.028
positive regulation of cellular amine metabolic processGO:003324050.028
cytokine productionGO:00018163190.028
posttranscriptional regulation of gene expressionGO:00106081550.027
modification dependent protein catabolic processGO:00199411330.026
hematopoietic progenitor cell differentiationGO:00022441430.026
cellular response to dna damage stimulusGO:00069742070.026
positive regulation of protein phosphorylationGO:00019342420.025
negative regulation of molecular functionGO:00440922580.025
cellular amine metabolic processGO:0044106440.024
spermatid differentiationGO:00485151150.024
regulation of cellular amine metabolic processGO:0033238200.024
embryonic placenta developmentGO:0001892980.024
ubiquitin dependent protein catabolic processGO:00065111290.024
limb morphogenesisGO:00351081490.024
regulation of cellular component biogenesisGO:00440871810.024
peptidyl amino acid modificationGO:00181933360.024
rna processingGO:00063961050.023
Mouse Rat
negative regulation of immune system processGO:00026832090.023
cellular protein catabolic processGO:00442571550.022
respiratory system developmentGO:00605411900.022
regulation of protein kinase activityGO:00458592320.022
Human
endocytosisGO:00068971680.022
Worm Fly
protein catabolic processGO:00301632210.022
positive regulation of organelle organizationGO:00106381280.022
rhythmic processGO:00485111740.022
methylationGO:00322591340.022
organelle assemblyGO:00709251770.021
positive regulation of mapk cascadeGO:00434101700.021
Fly
protein maturationGO:00516041760.021
negative regulation of protein metabolic processGO:00512482820.021
positive regulation of cell deathGO:00109422240.020
interspecies interaction between organismsGO:0044419830.020
histone methylationGO:0016571710.020
protein methylationGO:0006479810.020
cytoplasmic transportGO:00164822340.019
digestive system developmentGO:00551232000.019
blastocyst developmentGO:0001824800.019
stem cell differentiationGO:00488632680.019
apoptotic signaling pathwayGO:00971903060.019
positive regulation of kinase activityGO:00336741550.019
histone lysine methylationGO:0034968500.018
meiotic cell cycleGO:00513211220.018
nucleobase containing small molecule metabolic processGO:00550863520.018
leukocyte differentiationGO:00025213420.018
respiratory tube developmentGO:00303231670.018
limb developmentGO:00601731660.018
female gamete generationGO:0007292740.018
stem cell developmentGO:00488642190.018
lateral inhibitionGO:004633110.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.018
immune effector processGO:00022523210.017
intracellular protein transportGO:00068862040.017
cell type specific apoptotic processGO:00972852680.017
fertilizationGO:00095661270.017
lymphocyte mediated immunityGO:00024491390.017
regulation of protein serine threonine kinase activityGO:00719001570.017
Human
regulation of protein complex assemblyGO:0043254830.017
positive regulation of nervous system developmentGO:00519622210.017
positive regulation of protein kinase activityGO:00458601440.017
multicellular organismal homeostasisGO:00488711640.017
regulation of apoptotic signaling pathwayGO:20012331970.017
regulation of protein localizationGO:00328802310.017
meiotic nuclear divisionGO:00071261150.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
nucleoside triphosphate metabolic processGO:00091412300.016
heart morphogenesisGO:00030071780.016
proteasomal protein catabolic processGO:0010498980.016
chromosome segregationGO:0007059480.016
mitotic cell cycleGO:00002781950.016
regulation of chromosome organizationGO:0033044830.016
mapk cascadeGO:00001652810.016
Human Fly
appendage developmentGO:00487361660.016
negative regulation of nervous system developmentGO:00519611560.016
pharynx developmentGO:006046510.015
extracellular structure organizationGO:00430621480.015
hindbrain developmentGO:00309021280.015
urogenital system developmentGO:00016552610.015
meiotic cell cycle processGO:1903046770.015
mrna processingGO:0006397630.015
Mouse
nucleoside phosphate metabolic processGO:00067533380.015
placenta developmentGO:00018901400.015
organic cyclic compound catabolic processGO:19013612950.015
phospholipid metabolic processGO:0006644870.015
actin filament organizationGO:00070151130.015
male meiosis iGO:0007141160.015
sensory perceptionGO:00076002450.015
nuclear transportGO:00511691390.015
ribose phosphate metabolic processGO:00196932910.015
purine ribonucleotide catabolic processGO:00091542080.015
ossificationGO:00015032160.015
mitotic cell cycle processGO:19030471590.015
regulation of multi organism processGO:00439001110.015
protein processingGO:00164851630.014
positive regulation of growthGO:00459271040.014
multi organism behaviorGO:0051705620.014
t cell activationGO:00421102890.014
regulation of epithelial cell proliferationGO:00506781410.014
epithelial cell developmentGO:00020641590.014
symbiosis encompassing mutualism through parasitismGO:0044403830.014
regulation of protein processingGO:0070613960.014
viral life cycleGO:0019058360.014
morphogenesis of a branching epitheliumGO:00611381930.014
nucleocytoplasmic transportGO:00069131390.014
regulation of membrane potentialGO:00423911920.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.014
neural tube developmentGO:00219151600.014
renal system developmentGO:00720012250.014
regulation of cell divisionGO:0051302760.014
cellular response to gamma radiationGO:007148040.014
camera type eye developmentGO:00430102660.014
regulation of lymphocyte activationGO:00512492400.014
adaptive immune responseGO:00022501550.014
regulation of protein maturationGO:1903317960.014
muscle tissue developmentGO:00605373080.014
regulation of proteolysisGO:00301621640.013
cellular response to cytokine stimulusGO:00713451890.013
membrane organizationGO:00610242450.013
regulation of mapk cascadeGO:00434082480.013
Human Fly
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
innate immune responseGO:00450871570.013
sensory perception of mechanical stimulusGO:00509541070.013
protein alkylationGO:0008213810.013
cellular lipid metabolic processGO:00442553230.013
sensory system developmentGO:004888030.013
cell divisionGO:00513011200.013
organonitrogen compound catabolic processGO:19015652640.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
digestive tract morphogenesisGO:00485461470.013
regulation of cell projection organizationGO:00313442060.013
embryonic appendage morphogenesisGO:00351131260.013
regulation of defense responseGO:00313472330.013
negative regulation of multi organism processGO:0043901680.013
regulation of cellular response to stressGO:00801351590.013
negative regulation of cellular amine metabolic processGO:003323910.013
carbohydrate derivative catabolic processGO:19011362310.013
regulation of cell activationGO:00508652890.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
regulation of neuron deathGO:19012141340.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.012
Mouse
maintenance of locationGO:0051235890.012
alpha beta t cell activationGO:0046631910.012
oogenesisGO:0048477560.012
nucleotide metabolic processGO:00091173320.012
protein localization to organelleGO:00333651850.012
synapse organizationGO:00508081250.012
positive regulation of secondary heart field cardioblast proliferationGO:007251340.012
cation transmembrane transportGO:00986552660.012
regulation of stem cell proliferationGO:0072091780.012
regulation of cytokine productionGO:00018172660.012
small gtpase mediated signal transductionGO:0007264970.012
Fly
skeletal system developmentGO:00015013560.012
habituationGO:004695930.012
glycosyl compound metabolic processGO:19016572460.012
microtubule cytoskeleton organizationGO:00002261570.012
negative regulation of defense responseGO:0031348770.012
cellularizationGO:000734910.012
cellular protein complex assemblyGO:00436231160.012
negative regulation of mesenchymal cell proliferationGO:007220130.012
nucleoside phosphate catabolic processGO:19012922220.012
spermatid developmentGO:00072861080.012
translationGO:0006412930.012
locomotory behaviorGO:00076261950.012
cell maturationGO:00484691270.012
trophectodermal cell differentiationGO:0001829210.012
cellular response to organonitrogen compoundGO:00714171450.012
b cell activationGO:00421131610.012
leukocyte mediated immunityGO:00024431740.012
glycerolipid metabolic processGO:00464861220.012
hepaticobiliary system developmentGO:0061008670.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
cytokine mediated signaling pathwayGO:00192211150.012
regulation of translationGO:0006417710.011
epithelial tube formationGO:00721751300.011
lung developmentGO:00303241640.011
negative regulation of protein maturationGO:1903318790.011
homeostasis of number of cellsGO:00488722100.011
negative regulation of cellular catabolic processGO:0031330470.011
meiosis iGO:0007127600.011
positive regulation of apoptotic processGO:00430652170.011
action potentialGO:0001508780.011
regulation of hydrolase activityGO:00513362460.011
response to growth factorGO:00708481980.011
transmembrane transportGO:00550854120.011
regulation of vesicle mediated transportGO:00606271390.011
regulation of chromatin organizationGO:1902275570.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
cardiac muscle tissue developmentGO:00487381300.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.011
sensory perception of soundGO:0007605970.011
jak stat cascadeGO:0007259420.011
endodermal cell fate specificationGO:000171440.011
nucleotide catabolic processGO:00091662170.011
viral gene expressionGO:001908030.011
ear developmentGO:00435832000.011
mesenchymal cell proliferation involved in ureter developmentGO:007219840.011
negative regulation of protein processingGO:0010955790.011
purine nucleoside catabolic processGO:00061522050.011
regulation of viral transcriptionGO:004678230.011
multi multicellular organism processGO:00447061090.011
regulation of cellular catabolic processGO:00313292420.011
embryonic limb morphogenesisGO:00303261260.011
skeletal system morphogenesisGO:00487052030.011
stem cell maintenanceGO:00198271300.010
rna interferenceGO:001624620.010
gastrulationGO:00073691160.010
lymphocyte differentiationGO:00300982420.010
extrinsic apoptotic signaling pathwayGO:00971911260.010
regionalizationGO:00030023370.010
cell fate commitmentGO:00451652100.010
neuron deathGO:00709971540.010
muscle tissue morphogenesisGO:0060415530.010
morphogenesis of a branching structureGO:00017632030.010
mrna catabolic processGO:0006402220.010
negative regulation of cell proliferationGO:00082852960.010
purine nucleotide catabolic processGO:00061952110.010
cell activation involved in immune responseGO:00022631260.010
positive regulation of cell developmentGO:00107202370.010
ribonucleoside metabolic processGO:00091192450.010
vagus nerve developmentGO:002156430.010
primary neural tube formationGO:0014020950.010

Cdk12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.019
cancerDOID:16200.019
immune system diseaseDOID:291400.016