IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Tcirg1

T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3

(Aliases: Stv1,OC-116,oc,ATP6N1C,Vph1,OPTB1,Atp6i,ATP6a3,TIRC7)

Ensembl: ENSMUSG00000001750
Entrez: 27060
UniProtKB: Q9JHF5

Process Predictions
Disease Predictions

Tcirg1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
transmembrane transport	GO:0055085	412	0.718
ion transmembrane transport	GO:0034220	361	0.672
cation homeostasis	GO:0055080	212	0.644
cellular amine metabolic process	GO:0044106	44	0.615
amine metabolic process	GO:0009308	45	0.537
peptidyl amino acid modification	GO:0018193	336	0.523
myeloid cell homeostasis	GO:0002262	114	0.519
sphingolipid metabolic process	GO:0006665	45	0.510
reactive oxygen species metabolic process	GO:0072593	84	0.500
production of molecular mediator of immune response	GO:0002440	103	0.429
positive regulation of cellular amine metabolic process	GO:0033240	5	0.390
cellular amino acid metabolic process	GO:0006520	103	0.369
leukocyte homeostasis	GO:0001776	79	0.362
cell adhesion	GO:0007155	329	0.355
negative regulation of leukocyte differentiation	GO:1902106	51	0.343
muscle cell development	GO:0055001	133	0.328
cytokine production	GO:0001816	319	0.326
leukocyte proliferation	GO:0070661	172	0.322
gland development	GO:0048732	330	0.311
cation transport	GO:0006812	399	0.310
odontogenesis of dentin containing tooth	GO:0042475	66	0.307
regulation of cell migration	GO:0030334	219	0.304
metal ion homeostasis	GO:0055065	189	0.289
regulation of b cell differentiation	GO:0045577	23	0.287
defense response to other organism	GO:0098542	197	0.286
divalent inorganic cation transport	GO:0072511	178	0.283
negative regulation of lymphocyte activation	GO:0051250	91	0.280
sensory organ morphogenesis	GO:0090596	242	0.276
germ cell development	GO:0007281	185	0.272	Worm
calcium ion transport	GO:0006816	159	0.271
regulation of cellular amine metabolic process	GO:0033238	20	0.250
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.244
regulation of cell motility	GO:2000145	236	0.242
regulation of cytokine production	GO:0001817	266	0.238
regulation of myd88 independent toll like receptor signaling pathway	GO:0034127	1	0.238
regulation of metal ion transport	GO:0010959	106	0.235
molting cycle	GO:0042303	90	0.229	Worm
positive regulation of protein phosphorylation	GO:0001934	242	0.225
positive regulation of ion transmembrane transport	GO:0034767	24	0.224
myeloid dendritic cell differentiation	GO:0043011	16	0.216
immune effector process	GO:0002252	321	0.215
regulation of cytoskeleton organization	GO:0051493	122	0.212
epidermis development	GO:0008544	187	0.206
myeloid cell differentiation	GO:0030099	233	0.206
positive regulation of protein modification process	GO:0031401	299	0.201
lymphocyte proliferation	GO:0046651	164	0.196
regulation of ion transmembrane transport	GO:0034765	119	0.193
defense response to bacterium	GO:0042742	119	0.191
activation of innate immune response	GO:0002218	56	0.191
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.190
glycosphingolipid metabolic process	GO:0006687	18	0.188
negative regulation of cellular protein metabolic process	GO:0032269	247	0.184
regulation of actin cytoskeleton organization	GO:0032956	84	0.183
regulation of calcium ion transport	GO:0051924	69	0.179
regulation of myeloid cell differentiation	GO:0045637	96	0.175
macromolecule catabolic process	GO:0009057	281	0.173	Worm
regulation of chemokine secretion	GO:0090196	4	0.172
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.172
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.172
dendritic cell differentiation	GO:0097028	26	0.163
dendritic cell cytokine production	GO:0002371	3	0.162
toll like receptor signaling pathway	GO:0002224	38	0.161
liposaccharide metabolic process	GO:1903509	27	0.159
response to peptide	GO:1901652	136	0.158
organelle assembly	GO:0070925	177	0.154
positive regulation of transmembrane transport	GO:0034764	29	0.153
carbohydrate derivative catabolic process	GO:1901136	231	0.153
posttranscriptional regulation of gene expression	GO:0010608	155	0.153
cellular ketone metabolic process	GO:0042180	84	0.149
cellular chemical homeostasis	GO:0055082	215	0.148
epithelial cell proliferation	GO:0050673	174	0.146
regulation of vasculature development	GO:1901342	88	0.144
response to amino acid	GO:0043200	37	0.142
intracellular protein transport	GO:0006886	204	0.142
positive regulation of myeloid cell differentiation	GO:0045639	43	0.141
regulation of cellular component size	GO:0032535	121	0.139
innate immune response	GO:0045087	157	0.139
regulation of homeostatic process	GO:0032844	182	0.139
muscle tissue development	GO:0060537	308	0.138
actin polymerization or depolymerization	GO:0008154	54	0.137
cellular response to biotic stimulus	GO:0071216	92	0.134
regulation of actin filament length	GO:0030832	45	0.131
regulation of ion transport	GO:0043269	215	0.131
actin cytoskeleton organization	GO:0030036	220	0.129
regulation of organelle organization	GO:0033043	289	0.129
response to lipopolysaccharide	GO:0032496	128	0.129
regulation of cellular ketone metabolic process	GO:0010565	66	0.128
microglia differentiation	GO:0014004	2	0.127
negative regulation of myeloid cell differentiation	GO:0045638	38	0.127
development of primary female sexual characteristics	GO:0046545	73	0.125
regulation of actin filament based process	GO:0032970	99	0.124
negative regulation of cell activation	GO:0050866	111	0.124
leydig cell differentiation	GO:0033327	10	0.122
immune response regulating signaling pathway	GO:0002764	125	0.121
extrinsic apoptotic signaling pathway	GO:0097191	126	0.120
skeletal system development	GO:0001501	356	0.118
embryonic organ morphogenesis	GO:0048562	276	0.117
nucleoside catabolic process	GO:0009164	206	0.116
glycolipid metabolic process	GO:0006664	25	0.116
positive regulation of cytokine biosynthetic process	GO:0042108	40	0.115
calcium ion homeostasis	GO:0055074	127	0.114
rhythmic process	GO:0048511	174	0.114
ribose phosphate metabolic process	GO:0019693	291	0.114
tissue remodeling	GO:0048771	102	0.113
cellular response to lipopolysaccharide	GO:0071222	77	0.112
skeletal system morphogenesis	GO:0048705	203	0.112
nucleoside triphosphate metabolic process	GO:0009141	230	0.111
ruffle organization	GO:0031529	16	0.109
forebrain development	GO:0030900	302	0.109
apoptotic signaling pathway	GO:0097190	306	0.108
divalent inorganic cation homeostasis	GO:0072507	138	0.107
cd8 positive alpha beta t cell proliferation	GO:0035740	1	0.107
inorganic ion transmembrane transport	GO:0098660	234	0.106
ras protein signal transduction	GO:0007265	77	0.106
organonitrogen compound catabolic process	GO:1901565	264	0.106
leukocyte differentiation	GO:0002521	342	0.105
regulation of kinase activity	GO:0043549	249	0.105
positive regulation of osteoclast differentiation	GO:0045672	15	0.103
camera type eye development	GO:0043010	266	0.103
retina development in camera type eye	GO:0060041	119	0.103
female sex differentiation	GO:0046660	84	0.102
b cell activation	GO:0042113	161	0.102
extracellular structure organization	GO:0043062	148	0.102
negative regulation of toll like receptor signaling pathway	GO:0034122	14	0.101
actin filament organization	GO:0007015	113	0.100
small gtpase mediated signal transduction	GO:0007264	97	0.100
regulation of protein tyrosine kinase activity	GO:0061097	17	0.100
regulation of leukocyte differentiation	GO:1902105	159	0.099
carbohydrate metabolic process	GO:0005975	230	0.099
cation transmembrane transport	GO:0098655	266	0.099
myeloid leukocyte activation	GO:0002274	83	0.098
learning or memory	GO:0007611	148	0.098
positive regulation of dna biosynthetic process	GO:2000573	4	0.097
bone resorption	GO:0045453	38	0.097
development of primary sexual characteristics	GO:0045137	143	0.097	Worm
cognition	GO:0050890	149	0.097
guanosine containing compound metabolic process	GO:1901068	144	0.096
regulation of protein binding	GO:0043393	60	0.096
multicellular organismal homeostasis	GO:0048871	164	0.096
phagocytosis	GO:0006909	66	0.095
glycosyl compound metabolic process	GO:1901657	246	0.095
regulation of leukocyte mediated immunity	GO:0002703	104	0.095
regulation of cellular amino acid metabolic process	GO:0006521	5	0.094
peptidyl tyrosine modification	GO:0018212	145	0.093
regulation of transmembrane transport	GO:0034762	128	0.093
positive regulation of smooth muscle cell migration	GO:0014911	4	0.091
protein localization to nucleus	GO:0034504	121	0.090
regulation of purine nucleotide catabolic process	GO:0033121	122	0.090
ceramide biosynthetic process	GO:0046513	20	0.090
sensory perception of sound	GO:0007605	97	0.089
salivary gland morphogenesis	GO:0007435	33	0.089
positive regulation of myeloid leukocyte differentiation	GO:0002763	26	0.089
hair cycle	GO:0042633	90	0.089
cellular lipid metabolic process	GO:0044255	323	0.089
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.088
face morphogenesis	GO:0060325	29	0.088
modification dependent macromolecule catabolic process	GO:0043632	133	0.088
nucleoside metabolic process	GO:0009116	246	0.088
myeloid leukocyte differentiation	GO:0002573	119	0.088
positive regulation of kinase activity	GO:0033674	155	0.086
spermatid differentiation	GO:0048515	115	0.086
response to peptide hormone	GO:0043434	127	0.086
angiogenesis	GO:0001525	201	0.085
platelet derived growth factor receptor alpha signaling pathway	GO:0035790	3	0.085
protein localization to organelle	GO:0033365	185	0.084
negative regulation of cell proliferation	GO:0008285	296	0.084
pallium development	GO:0021543	120	0.084
adaptive immune response	GO:0002250	155	0.084
epithelial cell development	GO:0002064	159	0.084
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.084
striated muscle cell development	GO:0055002	125	0.083
i kappab kinase nf kappab signaling	GO:0007249	85	0.083
peptidyl tyrosine phosphorylation	GO:0018108	143	0.083
positive regulation of rho gtpase activity	GO:0032321	41	0.083
regulation of multi organism process	GO:0043900	111	0.083
negative regulation of molecular function	GO:0044092	258	0.082
immune response activating signal transduction	GO:0002757	116	0.082
alpha beta t cell differentiation	GO:0046632	69	0.082
positive regulation of cell motility	GO:2000147	116	0.081
regulation of lymphocyte activation	GO:0051249	240	0.081
sodium ion transport	GO:0006814	73	0.081
regulation of protein complex assembly	GO:0043254	83	0.081
cellular metal ion homeostasis	GO:0006875	151	0.081
striated muscle tissue development	GO:0014706	293	0.081
sensory perception	GO:0007600	245	0.081
leukocyte activation involved in immune response	GO:0002366	126	0.080
digestive tract development	GO:0048565	190	0.080
t cell differentiation	GO:0030217	174	0.080
dna metabolic process	GO:0006259	303	0.078
muscle cell differentiation	GO:0042692	261	0.078
cellular homeostasis	GO:0019725	240	0.077
regulation of transferase activity	GO:0051338	263	0.077
male sex differentiation	GO:0046661	109	0.077
regulation of vesicle mediated transport	GO:0060627	139	0.076
developmental programmed cell death	GO:0010623	41	0.076
detection of mechanical stimulus involved in sensory perception of sound	GO:0050910	16	0.076
platelet derived growth factor receptor signaling pathway	GO:0048008	32	0.075
membrane organization	GO:0061024	245	0.075
regulation of proteolysis	GO:0030162	164	0.074
skin development	GO:0043588	220	0.074
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.074
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.074
regulation of cell adhesion	GO:0030155	154	0.073
regulation of epithelial cell proliferation	GO:0050678	141	0.073
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.073
regulation of myd88 dependent toll like receptor signaling pathway	GO:0034124	2	0.072
purine nucleotide catabolic process	GO:0006195	211	0.072
epidermis morphogenesis	GO:0048730	33	0.071
stem cell differentiation	GO:0048863	268	0.070
leukocyte mediated immunity	GO:0002443	174	0.070
cellular protein complex assembly	GO:0043623	116	0.070
cellular response to dna damage stimulus	GO:0006974	207	0.070
osteoclast differentiation	GO:0030316	62	0.069
ribonucleoside metabolic process	GO:0009119	245	0.069
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.068
innate immune response activating signal transduction	GO:0002758	50	0.068
olfactory learning	GO:0008355	2	0.067
protein autophosphorylation	GO:0046777	61	0.067
development of primary male sexual characteristics	GO:0046546	88	0.067
aromatic compound catabolic process	GO:0019439	286	0.066
positive regulation of protein kinase activity	GO:0045860	144	0.066
regulation of membrane potential	GO:0042391	192	0.066
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.066
cellular ion homeostasis	GO:0006873	165	0.066
regulation of toll like receptor signaling pathway	GO:0034121	20	0.065
regulation of ras protein signal transduction	GO:0046578	114	0.065
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.065
digestive tract morphogenesis	GO:0048546	147	0.063
palate development	GO:0060021	76	0.063
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.063
digestive system development	GO:0055123	200	0.062
microtubule cytoskeleton organization	GO:0000226	157	0.062
positive regulation of innate immune response	GO:0045089	80	0.061
response to hypoxia	GO:0001666	58	0.061	Worm
single organismal cell cell adhesion	GO:0016337	131	0.061
cellular response to molecule of bacterial origin	GO:0071219	83	0.060
cellular component maintenance	GO:0043954	11	0.060
retina vasculature development in camera type eye	GO:0061298	17	0.060
regulation of cellular component biogenesis	GO:0044087	181	0.059
positive regulation of transferase activity	GO:0051347	167	0.059
protein targeting	GO:0006605	143	0.059
purine ribonucleotide catabolic process	GO:0009154	208	0.059
leukocyte migration	GO:0050900	124	0.059
positive regulation of chemotaxis	GO:0050921	38	0.059
positive regulation of cell migration	GO:0030335	109	0.058
gonad development	GO:0008406	141	0.058	Worm
head morphogenesis	GO:0060323	34	0.058
microtubule based process	GO:0007017	236	0.058
cellular component assembly involved in morphogenesis	GO:0010927	139	0.057
ovarian follicle development	GO:0001541	40	0.057
interspecies interaction between organisms	GO:0044419	83	0.057
actin filament polymerization	GO:0030041	44	0.056
renal system development	GO:0072001	225	0.056
cellular response to peptide	GO:1901653	92	0.056
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.056
macrophage differentiation	GO:0030225	20	0.056
cardiac muscle tissue development	GO:0048738	130	0.056
homeostasis of number of cells	GO:0048872	210	0.056
viral process	GO:0016032	41	0.056
reactive oxygen species biosynthetic process	GO:1903409	8	0.056
reactive nitrogen species metabolic process	GO:2001057	0	0.055
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.055
interferon beta biosynthetic process	GO:0045350	4	0.055
chromatin organization	GO:0006325	206	0.055
sensory perception of mechanical stimulus	GO:0050954	107	0.055
nucleoside phosphate catabolic process	GO:1901292	222	0.055
steroid metabolic process	GO:0008202	119	0.055
nucleoside phosphate metabolic process	GO:0006753	338	0.054
neuromuscular process	GO:0050905	99	0.053
mast cell proliferation	GO:0070662	4	0.053
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.053
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.053
intracellular receptor signaling pathway	GO:0030522	74	0.053
positive regulation of nucleoside metabolic process	GO:0045979	91	0.052
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.052
inflammatory response	GO:0006954	244	0.052
regulation of organ morphogenesis	GO:2000027	144	0.051
membrane lipid metabolic process	GO:0006643	53	0.051
myosin filament assembly	GO:0031034	2	0.051
organic anion transport	GO:0015711	137	0.051
cellularization	GO:0007349	1	0.051
response to radiation	GO:0009314	165	0.050
anatomical structure homeostasis	GO:0060249	145	0.050
regulation of lymphocyte differentiation	GO:0045619	107	0.050
regulation of angiogenesis	GO:0045765	81	0.050
purine nucleoside metabolic process	GO:0042278	241	0.050
negative regulation of granulocyte differentiation	GO:0030853	3	0.050
nuclear import	GO:0051170	95	0.050
detection of stimulus	GO:0051606	84	0.050
regulation of protein kinase activity	GO:0045859	232	0.050
spermatogenesis	GO:0007283	284	0.049
protein modification by small protein conjugation	GO:0032446	187	0.049
response to organonitrogen compound	GO:0010243	246	0.049
regulation of cell shape	GO:0008360	39	0.049
response to growth factor	GO:0070848	198	0.048
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.048
fibroblast growth factor receptor signaling pathway	GO:0008543	46	0.048
purine nucleotide metabolic process	GO:0006163	302	0.048
positive regulation of gtp catabolic process	GO:0033126	85	0.048
odontogenesis	GO:0042476	78	0.048
eye photoreceptor cell differentiation	GO:0001754	41	0.048
substrate adhesion dependent cell spreading	GO:0034446	30	0.048
endocytosis	GO:0006897	168	0.047	Worm
pattern recognition receptor signaling pathway	GO:0002221	47	0.047
purine containing compound metabolic process	GO:0072521	311	0.047
cytosolic calcium ion homeostasis	GO:0051480	70	0.046
positive regulation of cellular component biogenesis	GO:0044089	94	0.046
protein ubiquitination	GO:0016567	171	0.046
negative regulation of defense response	GO:0031348	77	0.046
male gonad development	GO:0008584	88	0.045
positive regulation of apoptotic process	GO:0043065	217	0.045
organic hydroxy compound metabolic process	GO:1901615	203	0.045
detection of mechanical stimulus involved in sensory perception	GO:0050974	23	0.045
cell junction organization	GO:0034330	77	0.045
positive regulation of phosphatidylinositol 3 kinase signaling	GO:0014068	20	0.044
positive regulation of gtpase activity	GO:0043547	85	0.044
mesenchymal cell development	GO:0014031	93	0.044
regulation of gtp catabolic process	GO:0033124	113	0.044
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.044
regulation of developmental pigmentation	GO:0048070	14	0.044
positive regulation of cell cycle	GO:0045787	92	0.044
negative regulation of cytokine production	GO:0001818	84	0.044
regulation of hydrolase activity	GO:0051336	246	0.044
positive regulation of leukocyte apoptotic process	GO:2000108	21	0.043
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.043
glial cell differentiation	GO:0010001	131	0.043
epithelial cell morphogenesis	GO:0003382	41	0.043
regulation of map kinase activity	GO:0043405	120	0.043
histone modification	GO:0016570	159	0.042
female gonad development	GO:0008585	71	0.042
regulation of cell cycle	GO:0051726	281	0.042
regulation of osteoclast differentiation	GO:0045670	36	0.042
nucleotide metabolic process	GO:0009117	332	0.042
negative regulation of immune effector process	GO:0002698	55	0.042
regulation of apoptotic signaling pathway	GO:2001233	197	0.042
epithelium migration	GO:0090132	63	0.042
erk1 and erk2 cascade	GO:0070371	77	0.041
positive regulation of ion transport	GO:0043270	65	0.041
negative regulation of nervous system development	GO:0051961	156	0.040
positive regulation of macrophage derived foam cell differentiation	GO:0010744	4	0.040
cellular response to cytokine stimulus	GO:0071345	189	0.040
response to molecule of bacterial origin	GO:0002237	143	0.040
regulation of nuclear division	GO:0051783	56	0.040
cell activation involved in immune response	GO:0002263	126	0.040
positive regulation of tyrosine phosphorylation of stat protein	GO:0042531	15	0.040
cell fate commitment	GO:0045165	210	0.040
b cell differentiation	GO:0030183	78	0.040
negative regulation of protein metabolic process	GO:0051248	282	0.039
regulation of mast cell activation involved in immune response	GO:0033006	17	0.039
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.039
cellular response to growth factor stimulus	GO:0071363	197	0.039
regulation of binding	GO:0051098	111	0.039
epithelial cell cell adhesion	GO:0090136	6	0.039
skin morphogenesis	GO:0043589	38	0.039
urogenital system development	GO:0001655	261	0.039
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.039
positive regulation of secretion	GO:0051047	130	0.038
anatomical structure arrangement	GO:0048532	20	0.038
regulation of neural retina development	GO:0061074	3	0.038
regulation of anatomical structure size	GO:0090066	178	0.038
gtp catabolic process	GO:0006184	143	0.038
embryonic skeletal system morphogenesis	GO:0048704	91	0.037
jak stat cascade	GO:0007259	42	0.037
covalent chromatin modification	GO:0016569	163	0.037
organelle fission	GO:0048285	170	0.037
negative regulation of phagocytosis	GO:0050765	4	0.037
negative regulation of cellular component organization	GO:0051129	194	0.036
regulation of interferon beta production	GO:0032648	13	0.036
interleukin 12 biosynthetic process	GO:0042090	8	0.036
spleen development	GO:0048536	39	0.036
cellular calcium ion homeostasis	GO:0006874	119	0.036
hair follicle morphogenesis	GO:0031069	29	0.036
tyrosine phosphorylation of stat protein	GO:0007260	23	0.035
regulation of protein localization	GO:0032880	231	0.035
protein import into nucleus	GO:0006606	95	0.035
positive regulation of map kinase activity	GO:0043406	84	0.035
regulation of tyrosine phosphorylation of stat protein	GO:0042509	20	0.035
spindle organization	GO:0007051	28	0.035
face development	GO:0060324	38	0.035
cardiac muscle cell development	GO:0055013	39	0.034
regulation of innate immune response	GO:0045088	91	0.034
myeloid dendritic cell activation	GO:0001773	25	0.034
cytokine mediated signaling pathway	GO:0019221	115	0.034
t cell receptor signaling pathway	GO:0050852	46	0.034
inorganic cation transmembrane transport	GO:0098662	207	0.034
regulation of cd8 positive alpha beta t cell activation	GO:2001185	3	0.034
peptidyl serine phosphorylation	GO:0018105	74	0.034
regulation of nucleotide catabolic process	GO:0030811	122	0.034
cd4 positive alpha beta t cell activation	GO:0035710	45	0.034
cellular response to erythropoietin	GO:0036018	1	0.034
cell division	GO:0051301	120	0.033
rac protein signal transduction	GO:0016601	13	0.033
regulation of macrophage differentiation	GO:0045649	9	0.033
sulfur compound metabolic process	GO:0006790	100	0.033
cellular response to organonitrogen compound	GO:0071417	145	0.033
regulation of smooth muscle cell migration	GO:0014910	6	0.033
activation of rac gtpase activity	GO:0032863	2	0.033
single organism nuclear import	GO:1902593	95	0.033
protein acylation	GO:0043543	64	0.033
purine ribonucleotide metabolic process	GO:0009150	290	0.033
morphogenesis of a polarized epithelium	GO:0001738	37	0.033
maintenance of location	GO:0051235	89	0.033	Worm
nucleobase containing small molecule metabolic process	GO:0055086	352	0.033
cell cell junction maintenance	GO:0045217	3	0.033
monosaccharide metabolic process	GO:0005996	106	0.033
regulation of retina development in camera type eye	GO:1902866	3	0.032
regulation of chemotaxis	GO:0050920	53	0.032
regionalization	GO:0003002	337	0.032
myd88 independent toll like receptor signaling pathway	GO:0002756	3	0.032
carbohydrate derivative biosynthetic process	GO:1901137	183	0.032
detection of external stimulus	GO:0009581	61	0.032
stem cell maintenance	GO:0019827	130	0.032
nucleocytoplasmic transport	GO:0006913	139	0.032
calcium ion transport into cytosol	GO:0060402	48	0.032
myosin filament organization	GO:0031033	3	0.032
organelle localization	GO:0051640	179	0.032
lymphocyte homeostasis	GO:0002260	64	0.032
regulation of cytoplasmic transport	GO:1903649	112	0.032
leukocyte chemotaxis	GO:0030595	69	0.032
cell adhesion mediated by integrin	GO:0033627	18	0.031
regulation of leukocyte proliferation	GO:0070663	121	0.031
hair follicle cell proliferation	GO:0071335	3	0.031
embryonic skeletal system development	GO:0048706	120	0.031
regulation of calcium ion transport into cytosol	GO:0010522	31	0.031
mesenchyme development	GO:0060485	152	0.031
negative regulation of interferon beta biosynthetic process	GO:0045358	1	0.031
platelet derived growth factor receptor beta signaling pathway	GO:0035791	4	0.031
hair follicle development	GO:0001942	85	0.031
detection of mechanical stimulus	GO:0050982	27	0.031
epithelial tube morphogenesis	GO:0060562	303	0.031
regulation of erythrocyte differentiation	GO:0045646	23	0.031
positive regulation of purine nucleotide catabolic process	GO:0033123	88	0.031
positive regulation of hydrolase activity	GO:0051345	148	0.030
regulation of ras gtpase activity	GO:0032318	88	0.030
protein import	GO:0017038	101	0.030
morphogenesis of a branching epithelium	GO:0061138	193	0.030
b cell apoptotic process	GO:0001783	19	0.030
mapk cascade	GO:0000165	281	0.030
regulation of cell activation	GO:0050865	289	0.030
multicellular organism growth	GO:0035264	161	0.030
modification dependent protein catabolic process	GO:0019941	133	0.030
negative regulation of t cell differentiation	GO:0045581	23	0.030
response to transforming growth factor beta	GO:0071559	88	0.030
hydrogen ion transmembrane transport	GO:1902600	25	0.030
bone remodeling	GO:0046849	53	0.030
regulation of tissue remodeling	GO:0034103	38	0.029
male gamete generation	GO:0048232	285	0.029
myofibril assembly	GO:0030239	34	0.029
response to light stimulus	GO:0009416	135	0.029
cellular macromolecule catabolic process	GO:0044265	206	0.029
regulation of establishment of planar polarity	GO:0090175	28	0.029
regulation of protein catabolic process	GO:0042176	108	0.029
regulation of hormone levels	GO:0010817	211	0.029
positive regulation of organelle organization	GO:0010638	128	0.029
locomotory behavior	GO:0007626	195	0.029
positive regulation of mapk cascade	GO:0043410	170	0.028
bmp signaling pathway	GO:0030509	93	0.028
regulation of erk1 and erk2 cascade	GO:0070372	71	0.028
exocytosis	GO:0006887	121	0.028
protein catabolic process	GO:0030163	221	0.028	Worm
cell maturation	GO:0048469	127	0.028
positive regulation of lipid kinase activity	GO:0090218	11	0.028
cytoplasmic transport	GO:0016482	234	0.028
regulation of cellular catabolic process	GO:0031329	242	0.028
interleukin 12 production	GO:0032615	32	0.028
nuclear division	GO:0000280	158	0.028
negative regulation of lymphocyte differentiation	GO:0045620	32	0.028
establishment of protein localization to organelle	GO:0072594	118	0.028
regulation of establishment of protein localization	GO:0070201	181	0.028
connective tissue development	GO:0061448	179	0.027
glycosylceramide metabolic process	GO:0006677	4	0.027
stem cell development	GO:0048864	219	0.027
positive regulation of defense response	GO:0031349	124	0.027
adherens junction organization	GO:0034332	28	0.027
body morphogenesis	GO:0010171	45	0.027	Worm
tolerance induction to self antigen	GO:0002513	4	0.027
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.027
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	62	0.027
limb morphogenesis	GO:0035108	149	0.027
fibroblast proliferation	GO:0048144	35	0.027
notch signaling pathway	GO:0007219	71	0.026
regulation of interferon beta biosynthetic process	GO:0045357	4	0.026
leukocyte cell cell adhesion	GO:0007159	14	0.026
morphogenesis of a branching structure	GO:0001763	203	0.026
actomyosin structure organization	GO:0031032	56	0.026
spermatid development	GO:0007286	108	0.026
divalent metal ion transport	GO:0070838	172	0.026
regulation of ion transmembrane transporter activity	GO:0032412	54	0.026
lamellipodium organization	GO:0097581	29	0.026
hindbrain development	GO:0030902	128	0.026
defense response to virus	GO:0051607	68	0.026

Tcirg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of metabolism	DOID:0014667	0.066
musculoskeletal system disease	DOID:17	0.034	Human
connective tissue disease	DOID:65	0.034	Human
disease of anatomical entity	DOID:7	0.034	Human

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network