Mus musculus

0 known processes

Ppp1r1a

protein phosphatase 1, regulatory (inhibitor) subunit 1A

(Aliases: I-1,0610038N18Rik)

Ppp1r1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monocarboxylic acid metabolic processGO:00327871910.360
cellular lipid metabolic processGO:00442553230.286
ion transmembrane transportGO:00342203610.281
purine nucleoside triphosphate metabolic processGO:00091442260.262
transmembrane transportGO:00550854120.246
cation transmembrane transportGO:00986552660.210
cellular amino acid metabolic processGO:00065201030.202
cellular ketone metabolic processGO:0042180840.201
cellular nitrogen compound catabolic processGO:00442702800.183
oxidation reduction processGO:00551143420.183
organic anion transportGO:00157111370.170
purine ribonucleoside triphosphate metabolic processGO:00092052200.155
ribonucleoside metabolic processGO:00091192450.154
regulation of transmembrane transportGO:00347621280.153
regulation of membrane potentialGO:00423911920.147
organic hydroxy compound metabolic processGO:19016152030.147
anion transportGO:00068201770.146
regulation of ion transportGO:00432692150.135
inorganic ion transmembrane transportGO:00986602340.133
nucleobase containing small molecule metabolic processGO:00550863520.131
aromatic compound catabolic processGO:00194392860.122
multicellular organismal response to stressGO:0033555620.122
mitochondrion organizationGO:00070051340.114
response to inorganic substanceGO:0010035960.113
nucleoside phosphate catabolic processGO:19012922220.111
ribonucleoside triphosphate metabolic processGO:00091992200.110
nucleoside triphosphate metabolic processGO:00091412300.107
negative regulation of phosphorylationGO:00423261660.103
purine nucleoside metabolic processGO:00422782410.101
synaptic transmissionGO:00072683290.100
regulation of heart contractionGO:0008016770.100
cation homeostasisGO:00550802120.100
nucleoside phosphate metabolic processGO:00067533380.096
organic acid transportGO:00158491010.096
ribonucleoside catabolic processGO:00424542060.094
response to nutrient levelsGO:00316671090.087
ribonucleoside triphosphate catabolic processGO:00092031990.086
response to light stimulusGO:00094161350.082
Mouse
regulation of engulfment of apoptotic cellGO:190107420.081
purine containing compound catabolic processGO:00725232130.080
cardiac muscle contractionGO:0060048320.079
amino acid transmembrane transportGO:0003333370.077
sodium ion transportGO:0006814730.077
organonitrogen compound catabolic processGO:19015652640.075
regulation of synaptic plasticityGO:0048167870.073
purine nucleotide metabolic processGO:00061633020.071
sodium ion transmembrane transportGO:0035725490.071
regulation of cellular ketone metabolic processGO:0010565660.069
purine nucleoside triphosphate catabolic processGO:00091462030.069
organophosphate catabolic processGO:00464342320.068
purine ribonucleoside metabolic processGO:00461282410.068
fatty acid metabolic processGO:00066311210.068
regulation of neurotransmitter levelsGO:0001505870.068
purine ribonucleotide catabolic processGO:00091542080.065
nucleotide metabolic processGO:00091173320.065
glycosyl compound catabolic processGO:19016582060.063
cation transportGO:00068123990.063
heterocycle catabolic processGO:00467002800.063
carbohydrate derivative catabolic processGO:19011362310.062
action potentialGO:0001508780.061
membrane organizationGO:00610242450.060
skin developmentGO:00435882200.057
cellular metal ion homeostasisGO:00068751510.057
calcium ion homeostasisGO:00550741270.056
small gtpase mediated signal transductionGO:0007264970.056
generation of precursor metabolites and energyGO:00060911030.056
amine metabolic processGO:0009308450.056
amino acid transportGO:0006865610.055
glycerolipid metabolic processGO:00464861220.055
matingGO:0007618270.054
Mouse
response to extracellular stimulusGO:00099911270.054
cellular potassium ion transportGO:0071804430.054
response to oxidative stressGO:00069791230.053
purine containing compound metabolic processGO:00725213110.053
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.053
membrane lipid biosynthetic processGO:0046467320.053
ribonucleotide metabolic processGO:00092592910.053
nucleotide catabolic processGO:00091662170.052
striated muscle contractionGO:0006941450.052
organic cyclic compound catabolic processGO:19013612950.052
actin filament organizationGO:00070151130.052
purine nucleoside catabolic processGO:00061522050.052
negative regulation of cellular amine metabolic processGO:003323910.052
muscle system processGO:00030121410.052
multicellular organismal signalingGO:0035637910.051
nucleoside metabolic processGO:00091162460.050
nucleoside catabolic processGO:00091642060.049
response to organic cyclic compoundGO:00140701980.048
organonitrogen compound biosynthetic processGO:19015661920.048
cellular carbohydrate metabolic processGO:00442621190.047
negative regulation of phosphate metabolic processGO:00459361840.047
defecationGO:003042110.047
locomotory behaviorGO:00076261950.046
cellular homeostasisGO:00197252400.046
regulation of protein localizationGO:00328802310.046
energy reserve metabolic processGO:0006112390.045
regulation of cellular amine metabolic processGO:0033238200.045
ribose phosphate metabolic processGO:00196932910.045
guanosine containing compound catabolic processGO:19010691440.044
fertilizationGO:00095661270.042
negative regulation of protein modification processGO:00314001630.042
negative regulation of phosphorus metabolic processGO:00105631840.042
regulation of cellular amino acid metabolic processGO:000652150.042
gtp metabolic processGO:00460391440.040
fat cell differentiationGO:00454441600.040
cardiac muscle cell contractionGO:008600370.040
adult locomotory behaviorGO:0008344910.039
regulation of metal ion transportGO:00109591060.039
sodium ion exportGO:007143620.039
regulation of cellular response to stressGO:00801351590.038
nucleoside triphosphate catabolic processGO:00091432050.038
purine ribonucleoside catabolic processGO:00461302050.038
carbohydrate transportGO:0008643620.037
response to peptideGO:19016521360.037
glycosyl compound metabolic processGO:19016572460.036
heart processGO:0003015940.036
purine ribonucleoside triphosphate catabolic processGO:00092071990.036
carboxylic acid transportGO:00469421000.035
lipid biosynthetic processGO:00086101790.035
heart contractionGO:0060047930.035
actin cytoskeleton organizationGO:00300362200.035
regulation of kinase activityGO:00435492490.035
glucose transportGO:0015758560.034
response to peptide hormoneGO:00434341270.034
nitrogen compound transportGO:00717052710.034
lipid localizationGO:00108761260.034
negative regulation of cellular amino acid metabolic processGO:004576300.034
regulation of organelle organizationGO:00330432890.034
divalent inorganic cation homeostasisGO:00725071380.034
purine ribonucleotide metabolic processGO:00091502900.033
cellular amine metabolic processGO:0044106440.033
metal ion homeostasisGO:00550651890.033
cellular calcium ion homeostasisGO:00068741190.033
regulation of hormone levelsGO:00108172110.032
response to temperature stimulusGO:0009266550.032
long chain fatty acid importGO:004453920.031
gtp catabolic processGO:00061841430.031
cellular response to oxidative stressGO:0034599760.031
multi organism behaviorGO:0051705620.030
Mouse
potassium ion transmembrane transportGO:0071805430.030
regulation of sodium ion transportGO:0002028290.030
spermatogenesisGO:00072832840.030
phospholipid metabolic processGO:0006644870.030
nucleoside monophosphate metabolic processGO:0009123850.029
negative regulation of cellular protein metabolic processGO:00322692470.029
cell adhesionGO:00071553290.029
ribonucleoside monophosphate metabolic processGO:0009161800.029
response to reactive oxygen speciesGO:0000302560.029
actin mediated cell contractionGO:0070252150.029
digestionGO:0007586400.029
purine nucleotide catabolic processGO:00061952110.029
regulation of nucleotide catabolic processGO:00308111220.028
endomembrane system organizationGO:00102561470.028
cytoplasmic transportGO:00164822340.028
transmission of nerve impulseGO:0019226760.028
multi multicellular organism processGO:00447061090.028
Mouse
maintenance of presynaptic active zone structureGO:004879010.027
glycosylationGO:0070085620.027
positive regulation of vasoconstrictionGO:004590740.027
response to molecule of bacterial originGO:00022371430.027
monosaccharide metabolic processGO:00059961060.027
regulation of transporter activityGO:0032409570.027
heart morphogenesisGO:00030071780.027
neurotransmitter transportGO:0006836760.026
regulation of ion transmembrane transporter activityGO:0032412540.026
negative regulation of protein metabolic processGO:00512482820.026
regulation of ion transmembrane transportGO:00347651190.026
protein oligomerizationGO:0051259670.026
regulation of anion transportGO:0044070270.026
learningGO:0007612980.026
Mouse
regulation of hydrolase activityGO:00513362460.025
very low density lipoprotein particle assemblyGO:003437920.025
response to organonitrogen compoundGO:00102432460.025
Mouse
organelle fissionGO:00482851700.025
microtubule based processGO:00070172360.024
adult walking behaviorGO:0007628410.024
negative regulation of molecular functionGO:00440922580.024
acyl coa biosynthetic processGO:007161670.024
carbohydrate metabolic processGO:00059752300.024
male gamete generationGO:00482322850.024
atp metabolic processGO:0046034750.024
carbohydrate derivative biosynthetic processGO:19011371830.024
organic hydroxy compound transportGO:0015850930.024
second messenger mediated signalingGO:0019932730.023
muscle cell differentiationGO:00426922610.023
myeloid cell homeostasisGO:00022621140.023
retina development in camera type eyeGO:00600411190.023
regulation of transferase activityGO:00513382630.023
apoptotic signaling pathwayGO:00971903060.023
regulation of cellular catabolic processGO:00313292420.023
sphingolipid biosynthetic processGO:0030148260.023
central nervous system neuron differentiationGO:00219531620.023
peptidyl amino acid modificationGO:00181933360.022
neuronal action potentialGO:0019228540.022
lipid catabolic processGO:0016042690.022
carboxylic acid biosynthetic processGO:0046394860.022
hexose transportGO:0008645560.022
positive regulation of cell deathGO:00109422240.022
response to acid chemicalGO:00011011110.022
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.022
steroid metabolic processGO:00082021190.022
regulation of body fluid levelsGO:00508781620.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
nucleocytoplasmic transportGO:00069131390.021
behavioral response to nutrientGO:005178010.021
asymmetric stem cell divisionGO:009872230.021
protein homooligomerizationGO:0051260430.021
posttranscriptional regulation of gene expressionGO:00106081550.021
regulation of actin filament based processGO:0032970990.021
monosaccharide transportGO:0015749580.021
regulation of cell cycle processGO:00105641600.021
microtubule polymerization or depolymerizationGO:0031109260.021
negative regulation of protein phosphorylationGO:00019331260.021
organic acid biosynthetic processGO:0016053860.021
endocytosisGO:00068971680.020
renal sodium ion transportGO:000309620.020
monocarboxylic acid transportGO:0015718440.020
multicellular organism growthGO:00352641610.020
rho protein signal transductionGO:0007266320.020
carbohydrate homeostasisGO:00335001280.020
regulation of anatomical structure sizeGO:00900661780.020
carbohydrate biosynthetic processGO:0016051740.020
regulation of system processGO:00440572000.020
neutral lipid metabolic processGO:0006638570.020
organophosphate biosynthetic processGO:00904071220.020
establishment of vesicle localizationGO:0051650810.019
vitamin transportGO:0051180100.019
small molecule biosynthetic processGO:00442831320.019
small molecule catabolic processGO:0044282710.019
muscle tissue developmentGO:00605373080.019
engulfment of apoptotic cellGO:004365230.019
neurotransmitter secretionGO:0007269620.019
response to insulinGO:00328681000.019
regulation of purine nucleotide metabolic processGO:19005421690.019
regulation of neuron differentiationGO:00456642810.019
axonogenesisGO:00074092740.019
regulation of inward rectifier potassium channel activityGO:190197910.019
negative regulation of cytoskeleton organizationGO:0051494360.019
vasoconstrictionGO:0042310270.018
ventricular cardiac muscle cell action potentialGO:008600540.018
peptide transportGO:00158331330.018
intracellular protein transportGO:00068862040.018
cellular response to hormone stimulusGO:00328701500.018
circulatory system processGO:00030131970.018
ribonucleoside monophosphate catabolic processGO:0009158570.018
mitotic cell cycle processGO:19030471590.018
acetylcholine catabolic processGO:000658110.018
inorganic cation transmembrane transportGO:00986622070.018
myeloid cell differentiationGO:00300992330.018
regulation of tube sizeGO:0035150570.018
amide transportGO:00428861380.018
macromolecule methylationGO:00434141200.018
regulation of intracellular transportGO:00323861590.018
regulation of sodium ion transmembrane transportGO:190230590.017
negative regulation of intracellular signal transductionGO:19025321670.017
regulation of proteolysisGO:00301621640.017
regulation of ras gtpase activityGO:0032318880.017
vesicle organizationGO:0016050600.017
cellular protein complex assemblyGO:00436231160.017
membrane lipid metabolic processGO:0006643530.017
organelle localizationGO:00516401790.017
regulation of nucleotide metabolic processGO:00061401690.017
sensory perceptionGO:00076002450.017
positive regulation of cellular amine metabolic processGO:003324050.017
coenzyme metabolic processGO:0006732520.017
tissue homeostasisGO:00018941150.017
inter male aggressive behaviorGO:000212130.017
mating behaviorGO:0007617200.017
Mouse
skeletal muscle organ developmentGO:00605381630.017
multi organism reproductive behaviorGO:0044705290.017
Mouse
ceramide metabolic processGO:0006672310.017
cell cell junction organizationGO:0045216720.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
protein catabolic processGO:00301632210.017
ribonucleotide catabolic processGO:00092612080.017
regulation of protein kinase activityGO:00458592320.017
positive regulation of inositol phosphate biosynthetic processGO:006073220.016
digestive system developmentGO:00551232000.016
neural precursor cell proliferationGO:00613511210.016
regulation of endocytosisGO:0030100690.016
nucleoside monophosphate catabolic processGO:0009125590.016
sensory organ morphogenesisGO:00905962420.016
potassium ion transportGO:0006813520.016
short chain fatty acid catabolic processGO:001962620.016
negative regulation of organelle organizationGO:0010639900.016
cellular protein catabolic processGO:00442571550.016
striated muscle tissue developmentGO:00147062930.016
organic hydroxy compound biosynthetic processGO:1901617770.016
mapk cascadeGO:00001652810.016
protein maturationGO:00516041760.016
fatty acid biosynthetic processGO:0006633410.016
regulation of phGO:0006885260.016
glycolipid biosynthetic processGO:0009247130.016
positive regulation of nucleotide metabolic processGO:00459811140.016
proteolysis involved in cellular protein catabolic processGO:00516031470.015
sialylationGO:0097503140.015
anatomical structure homeostasisGO:00602491450.015
cellular response to peptide hormone stimulusGO:0071375920.015
response to metal ionGO:0010038470.015
monocarboxylic acid biosynthetic processGO:0072330610.015
nuclear transportGO:00511691390.015
brown fat cell differentiationGO:0050873360.015
mitotic cell cycleGO:00002781950.015
visual behaviorGO:0007632450.015
Mouse
cofactor metabolic processGO:0051186800.015
localization within membraneGO:005166840.015
divalent metal ion transportGO:00708381720.015
morphogenesis of a polarized epitheliumGO:0001738370.015
choline metabolic processGO:001969510.015
ras protein signal transductionGO:0007265770.015
g protein coupled receptor signaling pathwayGO:00071862430.015
negative regulation of cellular component organizationGO:00511291940.015
single organism cell adhesionGO:00986021560.015
interspecies interaction between organismsGO:0044419830.015
protein localization to membraneGO:00726571080.015
muscle contractionGO:00069361010.015
regulation of mapk cascadeGO:00434082480.015
cell substrate adhesionGO:00315891300.015
cell type specific apoptotic processGO:00972852680.014
synaptic vesicle fusion to presynaptic membraneGO:003162930.014
vascular process in circulatory systemGO:0003018620.014
dna metabolic processGO:00062593030.014
response to radiationGO:00093141650.014
Mouse
protein processingGO:00164851630.014
cardiocyte differentiationGO:0035051870.014
calcium mediated signalingGO:0019722460.014
anion transmembrane transportGO:0098656710.014
energy derivation by oxidation of organic compoundsGO:0015980770.014
positive regulation of mechanoreceptor differentiationGO:004563310.014
response to oxygen levelsGO:0070482620.014
energy coupled proton transmembrane transport against electrochemical gradientGO:001598830.014
vesicle fusionGO:0006906160.014
hematopoietic progenitor cell differentiationGO:00022441430.014
membrane fusionGO:0061025380.014
cellular response to lipidGO:00713961450.014
purine nucleoside monophosphate metabolic processGO:0009126810.014
protein polymerizationGO:0051258570.014
fluid transportGO:0042044140.014
regulation of protein serine threonine kinase activityGO:00719001570.014
rac protein signal transductionGO:0016601130.014
protein modification by small protein conjugation or removalGO:00706472070.014
relaxation of muscleGO:0090075180.014
regulation of cytoskeleton organizationGO:00514931220.014
response to amphetamineGO:0001975160.014
Mouse
macromolecule catabolic processGO:00090572810.014
cellular response to organonitrogen compoundGO:00714171450.014
single fertilizationGO:0007338820.014
fast calcium ion dependent exocytosis of neurotransmitterGO:009874610.014
regulation of cell migrationGO:00303342190.013
regulation of gtp catabolic processGO:00331241130.013
molting cycleGO:0042303900.013
regulation of vesicle mediated transportGO:00606271390.013
atp catabolic processGO:0006200550.013
regulation of g protein activated inward rectifier potassium channel activityGO:190012810.013
purine ribonucleoside monophosphate metabolic processGO:0009167800.013
hormone metabolic processGO:0042445860.013
camera type eye developmentGO:00430102660.013
regulation of lipid metabolic processGO:00192161180.013
isoprenoid metabolic processGO:0006720290.013
regulation of exit from mitosisGO:000709610.013
cellular amide metabolic processGO:0043603580.013
neuron neuron synaptic transmissionGO:0007270690.013
regulation of purine nucleotide catabolic processGO:00331211220.013
nucleotide biosynthetic processGO:0009165780.013
protein localization to organelleGO:00333651850.013
regulation of sodium ion transmembrane transporter activityGO:200064990.013
wnt signaling pathwayGO:00160551880.013
positive regulation of apoptotic processGO:00430652170.013
peptide metabolic processGO:0006518460.013
reactive oxygen species metabolic processGO:0072593840.013
homeostasis of number of cellsGO:00488722100.013
deltoid tuberosity developmentGO:003599330.013
development of primary sexual characteristicsGO:00451371430.013
regulation of feeding behaviorGO:006025930.013
positive regulation of striated muscle contractionGO:004598930.013
nuclear divisionGO:00002801580.012
acylglycerol metabolic processGO:0006639550.012
carbohydrate catabolic processGO:0016052320.012
activation of adenylate cyclase activityGO:000719040.012
sphingolipid metabolic processGO:0006665450.012
negative regulation of cell proliferationGO:00082852960.012
cellular glucan metabolic processGO:0006073320.012
plasma membrane organizationGO:0007009900.012
response to hypoxiaGO:0001666580.012
arachidonic acid metabolite production involved in inflammatory responseGO:000253820.012
response to starvationGO:0042594650.012
actin filament based movementGO:0030048230.012
proton transportGO:0015992350.012
adult behaviorGO:00305341350.012
regulation of myeloid cell differentiationGO:0045637960.012
regulation of cardiac muscle contractionGO:0055117210.012
symbiosis encompassing mutualism through parasitismGO:0044403830.012
glycerolipid biosynthetic processGO:0045017500.012
cellular chemical homeostasisGO:00550822150.012
receptor biosynthetic processGO:003280030.012
positive regulation of programmed cell deathGO:00430682180.012
regulation of defense responseGO:00313472330.012
cofactor biosynthetic processGO:0051188410.012
lipid transportGO:0006869980.012
purine ribonucleoside monophosphate catabolic processGO:0009169570.012
ceramide biosynthetic processGO:0046513200.012
hatchingGO:003518840.012
regulation of cell motilityGO:20001452360.012
appendage developmentGO:00487361660.012
cellular macromolecule catabolic processGO:00442652060.012
purine nucleoside monophosphate catabolic processGO:0009128580.012
phosphatidylethanolamine biosynthetic processGO:000664620.012
cellular response to metal ionGO:0071248310.012
erk1 and erk2 cascadeGO:0070371770.012
response to decreased oxygen levelsGO:0036293590.012
sodium ion importGO:009736910.011
rna processingGO:00063961050.011
response to monosaccharideGO:0034284670.011
positive regulation of ion transportGO:0043270650.011
inorganic anion transportGO:0015698430.011
hydrogen transportGO:0006818350.011
regulation of microtubule cytoskeleton organizationGO:0070507370.011
negative regulation of cell cycleGO:00457861230.011
protein targetingGO:00066051430.011
substantia nigra developmentGO:002176220.011
regulation of intracellular protein transportGO:0033157820.011
skeletal system morphogenesisGO:00487052030.011
epidermis developmentGO:00085441870.011
regulation of blood vessel sizeGO:0050880560.011
maintenance of locationGO:0051235890.011
multicellular organismal agingGO:0010259240.011
positive regulation of glycolytic processGO:004582140.011
axon ensheathmentGO:0008366760.011
lipoprotein metabolic processGO:0042157430.011
regulation of potassium ion transmembrane transportGO:1901379110.011
asymmetric neuroblast divisionGO:005505910.011
mrna metabolic processGO:0016071840.011
reproductive behaviorGO:0019098320.011
Mouse
glucose metabolic processGO:0006006920.011
cellular response to acid chemicalGO:0071229680.011
lipid modificationGO:0030258650.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
positive regulation of purine nucleotide catabolic processGO:0033123880.011
cellular response to hexose stimulusGO:0071331470.011
regulation of protein kinase b signalingGO:0051896560.011
wound healingGO:00420601570.011
negative regulation of microtubule polymerizationGO:003111520.011
glycoprotein metabolic processGO:00091001160.011
negative regulation of transferase activityGO:0051348850.011
phospholipid biosynthetic processGO:0008654360.011
regulation of blood circulationGO:1903522930.011
response to drugGO:0042493750.011
positive regulation of blood circulationGO:1903524220.011
peptidyl tyrosine phosphorylationGO:00181081430.011
regulation of rho protein signal transductionGO:0035023710.011
hormone secretionGO:00468791280.011
cellular ion homeostasisGO:00068731650.011
modification dependent protein catabolic processGO:00199411330.010
phosphatidylethanolamine metabolic processGO:004633720.010
phosphatidic acid biosynthetic processGO:000665420.010
negative regulation of response to oxidative stressGO:1902883100.010
blood circulationGO:00080151950.010
regulation of retina development in camera type eyeGO:190286630.010
positive regulation of cd4 positive alpha beta t cell proliferationGO:200056310.010
ameboidal type cell migrationGO:00016671280.010
sulfur compound metabolic processGO:00067901000.010
apoptotic mitochondrial changesGO:0008637480.010
negative regulation of muscle contractionGO:0045932120.010
cell junction maintenanceGO:003433140.010
response to steroid hormoneGO:0048545560.010
cell divisionGO:00513011200.010
determination of left right symmetryGO:0007368800.010
peptidyl serine modificationGO:0018209830.010
establishment of protein localization to vacuoleGO:007266640.010
positive regulation of potassium ion transmembrane transporter activityGO:190101810.010
negative regulation of immune system processGO:00026832090.010
negative regulation of microtubule polymerization or depolymerizationGO:0031111150.010

Ppp1r1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.147
disease of anatomical entityDOID:700.147
central nervous system diseaseDOID:33100.049
disease of metabolismDOID:001466700.025
neurodegenerative diseaseDOID:128900.020
sensory system diseaseDOID:005015500.015
neuropathyDOID:87000.015
brain diseaseDOID:93600.013
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
acquired metabolic diseaseDOID:006015800.011