Mus musculus

21 known processes

Map2k2

mitogen-activated protein kinase kinase 2

(Aliases: MEK2,Prkmk2,AA589381,MK2)

Map2k2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of protein serine threonine kinase activityGO:00719001570.386
Human Yeast Mouse Rat Worm
nucleoside metabolic processGO:00091162460.338
regulation of kinase activityGO:00435492490.331
Human Yeast Mouse Rat Worm
male gamete generationGO:00482322850.321
positive regulation of protein modification processGO:00314012990.270
Human Yeast Mouse Rat Worm
spermatogenesisGO:00072832840.255
positive regulation of nucleotide catabolic processGO:0030813880.253
glycosyl compound catabolic processGO:19016582060.249
regulation of cellular response to stressGO:00801351590.242
Yeast
negative regulation of molecular functionGO:00440922580.239
ribonucleoside triphosphate catabolic processGO:00092031990.236
purine nucleoside metabolic processGO:00422782410.218
ribose phosphate metabolic processGO:00196932910.213
protein catabolic processGO:00301632210.209
Worm
glycosyl compound metabolic processGO:19016572460.209
oocyte constructionGO:000730820.201
muscle tissue developmentGO:00605373080.200
nucleoside phosphate metabolic processGO:00067533380.199
actin cytoskeleton organizationGO:00300362200.185
Yeast
purine ribonucleoside metabolic processGO:00461282410.180
purine nucleoside triphosphate metabolic processGO:00091442260.179
organonitrogen compound catabolic processGO:19015652640.169
purine containing compound catabolic processGO:00725232130.169
nucleoside catabolic processGO:00091642060.167
ribonucleotide metabolic processGO:00092592910.167
organic cyclic compound catabolic processGO:19013612950.164
cell fate commitmentGO:00451652100.153
g protein coupled receptor signaling pathwayGO:00071862430.149
Yeast
stem cell differentiationGO:00488632680.145
oocyte axis specificationGO:000730920.144
positive regulation of protein phosphorylationGO:00019342420.144
Human Yeast Mouse Rat Worm
nucleoside phosphate catabolic processGO:19012922220.143
mapk cascadeGO:00001652810.141
Human Yeast Mouse Rat Worm Fly
purine ribonucleoside triphosphate metabolic processGO:00092052200.140
positive regulation of nervous system developmentGO:00519622210.135
nucleobase containing small molecule metabolic processGO:00550863520.134
regulation of protein kinase activityGO:00458592320.133
Human Yeast Mouse Rat Worm
purine ribonucleoside catabolic processGO:00461302050.132
gtp metabolic processGO:00460391440.127
purine nucleotide catabolic processGO:00061952110.122
guanosine containing compound metabolic processGO:19010681440.121
aromatic compound catabolic processGO:00194392860.120
cellular nitrogen compound catabolic processGO:00442702800.119
ribonucleoside metabolic processGO:00091192450.118
regulation of mapk cascadeGO:00434082480.117
Human Yeast Mouse Rat Worm Fly
positive regulation of mapk cascadeGO:00434101700.116
Human Yeast Mouse Rat Worm Fly
apoptotic signaling pathwayGO:00971903060.114
peptidyl amino acid modificationGO:00181933360.112
Human
purine ribonucleoside triphosphate catabolic processGO:00092071990.112
macromolecule catabolic processGO:00090572810.112
Worm
regulation of transferase activityGO:00513382630.110
Human Yeast Mouse Rat Worm
cell fate specificationGO:0001708720.109
heterocycle catabolic processGO:00467002800.109
development of primary sexual characteristicsGO:00451371430.107
Worm
digestive system developmentGO:00551232000.104
muscle cell differentiationGO:00426922610.102
positive regulation of cell projection organizationGO:0031346950.100
positive regulation of purine nucleotide catabolic processGO:0033123880.100
positive regulation of neuron differentiationGO:00456661410.096
positive regulation of protein serine threonine kinase activityGO:00719021060.096
Human Yeast Mouse Rat Worm
compound eye developmentGO:004874910.094
germ cell developmentGO:00072811850.093
Fly
nucleoside triphosphate metabolic processGO:00091412300.093
ribonucleoside triphosphate metabolic processGO:00091992200.093
protein modification by small protein conjugation or removalGO:00706472070.091
carbohydrate derivative catabolic processGO:19011362310.089
regulation of cell migrationGO:00303342190.088
nucleotide metabolic processGO:00091173320.087
regulation of nucleoside metabolic processGO:00091181300.087
spermatid differentiationGO:00485151150.086
regulation of neuron apoptotic processGO:00435231220.084
purine nucleoside catabolic processGO:00061522050.084
gastrulationGO:00073691160.084
regulation of exocytosisGO:0017157610.082
cellular ketone metabolic processGO:0042180840.080
response to oxidative stressGO:00069791230.080
regulation of cell cycle processGO:00105641600.077
organophosphate catabolic processGO:00464342320.077
purine nucleoside triphosphate catabolic processGO:00091462030.076
establishment or maintenance of bipolar cell polarityGO:0061245210.076
digestive tract morphogenesisGO:00485461470.075
cell type specific apoptotic processGO:00972852680.075
purine ribonucleotide catabolic processGO:00091542080.075
purine ribonucleotide metabolic processGO:00091502900.075
regulation of epithelial cell proliferationGO:00506781410.075
positive regulation of protein kinase activityGO:00458601440.075
Human Yeast Mouse Rat Worm
regulation of cellular ketone metabolic processGO:0010565660.074
positive regulation of nucleotide metabolic processGO:00459811140.074
spermatid developmentGO:00072861080.072
regionalizationGO:00030023370.072
Fly
negative regulation of synaptic vesicle transportGO:190280430.070
positive regulation of cell developmentGO:00107202370.070
rhythmic processGO:00485111740.069
cellular amino acid metabolic processGO:00065201030.068
skeletal muscle organ developmentGO:00605381630.067
multicellular organism growthGO:00352641610.065
neuron apoptotic processGO:00514021420.065
cytoplasmic transportGO:00164822340.064
Yeast
negative regulation of protein metabolic processGO:00512482820.064
digestive tract developmentGO:00485651900.063
muscle system processGO:00030121410.062
associative learningGO:0008306610.062
actomyosin structure organizationGO:0031032560.062
ribonucleotide catabolic processGO:00092612080.061
lung morphogenesisGO:0060425500.060
positive regulation of kinase activityGO:00336741550.060
Human Yeast Mouse Rat Worm
intrinsic apoptotic signaling pathwayGO:00971931320.060
establishment of organelle localizationGO:00516561220.059
regulation of g protein coupled receptor protein signaling pathwayGO:0008277370.059
Yeast
regulation of actin filament based processGO:0032970990.059
respiratory system developmentGO:00605411900.058
regulation of hydrolase activityGO:00513362460.058
negative regulation of synaptic vesicle exocytosisGO:200030130.058
striated muscle cell developmentGO:00550021250.057
regulation of neuron differentiationGO:00456642810.056
neuron deathGO:00709971540.056
carbon catabolite activation of transcriptionGO:004599140.055
positive regulation of erk1 and erk2 cascadeGO:0070374470.055
Fly
stem cell developmentGO:00488642190.055
regulation of cell cycleGO:00517262810.055
regulation of defense responseGO:00313472330.055
striated muscle tissue developmentGO:00147062930.055
epithelial tube morphogenesisGO:00605623030.054
negative regulation of neuron deathGO:1901215980.053
myosin filament organizationGO:003103330.052
positive regulation of nucleoside metabolic processGO:0045979910.051
zygotic determination of anterior posterior axis embryoGO:000735430.051
Fly
regulation of organelle organizationGO:00330432890.051
social behaviorGO:0035176210.050
regulation of translationGO:0006417710.049
negative regulation of cellular protein metabolic processGO:00322692470.048
oocyte differentiationGO:0009994350.048
response to radiationGO:00093141650.048
regulation of vesicle mediated transportGO:00606271390.047
response to light stimulusGO:00094161350.047
cellular amine metabolic processGO:0044106440.047
nucleotide catabolic processGO:00091662170.046
carbohydrate derivative biosynthetic processGO:19011371830.046
positive regulation of organelle organizationGO:00106381280.046
protein modification by small protein conjugationGO:00324461870.045
membrane organizationGO:00610242450.045
cell maturationGO:00484691270.045
placenta blood vessel developmentGO:0060674310.044
Mouse
positive regulation of purine nucleotide metabolic processGO:19005441140.044
negative regulation of neuron apoptotic processGO:0043524920.044
amine metabolic processGO:0009308450.044
regulation of synaptic plasticityGO:0048167870.044
muscle cell developmentGO:00550011330.044
cellular response to extracellular stimulusGO:0031668810.043
regulation of cell motilityGO:20001452360.043
neurotransmitter secretionGO:0007269620.042
ribonucleoside catabolic processGO:00424542060.042
proteasomal protein catabolic processGO:0010498980.041
regulation of jnk cascadeGO:0046328620.040
response to heatGO:0009408270.040
Yeast
epidermis developmentGO:00085441870.040
Mouse
adherens junction organizationGO:0034332280.040
regulation of purine nucleotide metabolic processGO:19005421690.039
negative regulation of ras gtpase activityGO:003426130.039
adiponectin activated signaling pathwayGO:003321140.039
negative regulation of macroautophagyGO:001624250.039
cellular lipid metabolic processGO:00442553230.039
epidermal growth factor receptor signaling pathwayGO:0007173280.038
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.038
purine nucleotide metabolic processGO:00061633020.038
positive regulation of cell migrationGO:00303351090.038
embryonic placenta developmentGO:0001892980.038
Mouse
skin developmentGO:00435882200.038
Mouse
regulation of cellular amine metabolic processGO:0033238200.038
regulation of purine nucleotide catabolic processGO:00331211220.038
protein import into nucleusGO:0006606950.038
Yeast
exocytosisGO:00068871210.038
protein ubiquitinationGO:00165671710.037
negative regulation of protein phosphorylationGO:00019331260.037
macroautophagyGO:0016236210.037
wnt signaling pathwayGO:00160551880.036
regulation of secretion by cellGO:19035302490.036
protein oligomerizationGO:0051259670.036
positive regulation of cellular catabolic processGO:00313311480.035
positive regulation of cellular amine metabolic processGO:003324050.035
negative regulation of fibroblast migrationGO:001076420.035
response to molecule of bacterial originGO:00022371430.035
positive regulation of gtp catabolic processGO:0033126850.035
cellular protein catabolic processGO:00442571550.034
establishment of vesicle localizationGO:0051650810.034
negative regulation of cell cycle processGO:0010948690.034
negative regulation of cell proliferationGO:00082852960.034
cell adhesionGO:00071553290.034
circadian rhythmGO:00076231140.034
cell growthGO:00160491300.034
Yeast
erbb signaling pathwayGO:0038127320.034
endocytosisGO:00068971680.034
leukocyte proliferationGO:00706611720.034
positive regulation of jnk cascadeGO:0046330460.034
modification dependent protein catabolic processGO:00199411330.034
response to temperature stimulusGO:0009266550.033
Yeast
organonitrogen compound biosynthetic processGO:19015661920.033
regulation of actin cytoskeleton organizationGO:0032956840.033
purine containing compound metabolic processGO:00725213110.033
immune response regulating signaling pathwayGO:00027641250.033
cellular response to starvationGO:0009267570.033
regulation of cellular catabolic processGO:00313292420.033
ameboidal type cell migrationGO:00016671280.032
Fly
cellular response to cytokine stimulusGO:00713451890.032
response to starvationGO:0042594650.032
regulation of muscle tissue developmentGO:1901861970.032
gonad developmentGO:00084061410.031
Worm
mitotic cell cycle processGO:19030471590.031
neurotransmitter transportGO:0006836760.030
epithelial cell proliferationGO:00506731740.030
gtp catabolic processGO:00061841430.030
developmental maturationGO:00217001930.030
posttranscriptional regulation of gene expressionGO:00106081550.030
negative regulation of intracellular signal transductionGO:19025321670.030
cellular response to lipopolysaccharideGO:0071222770.030
positive regulation of cellular amino acid metabolic processGO:004576430.029
cellular macromolecule catabolic processGO:00442652060.029
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.029
segmentationGO:0035282930.029
Fly
regulation of erk1 and erk2 cascadeGO:0070372710.029
Fly
learningGO:0007612980.029
positive regulation of rac gtpase activityGO:0032855140.029
protein localization to organelleGO:00333651850.029
Yeast
female gamete generationGO:0007292740.028
Fly
camera type eye developmentGO:00430102660.028
positive regulation of ruffle assemblyGO:190002910.028
regulation of cellular amino acid metabolic processGO:000652150.028
muscle contractionGO:00069361010.028
cardiac muscle cell differentiationGO:0055007690.028
regulation of leukocyte proliferationGO:00706631210.028
nucleoside triphosphate catabolic processGO:00091432050.027
regulation of macroautophagyGO:0016241120.027
cellular response to growth factor stimulusGO:00713631970.027
regulation of nucleotide catabolic processGO:00308111220.027
regulation of stress activated mapk cascadeGO:0032872690.027
multi organism behaviorGO:0051705620.027
cell substrate adhesionGO:00315891300.027
regulation of wnt signaling pathwayGO:00301111230.027
cell cycle arrestGO:0007050370.027
positive regulation of transferase activityGO:00513471670.027
Human Yeast Mouse Rat Worm
regulation of neuronal synaptic plasticityGO:0048168300.027
response to inorganic substanceGO:0010035960.026
positive regulation of ras protein signal transductionGO:0046579130.026
Fly
second messenger mediated signalingGO:0019932730.026
actin filament organizationGO:00070151130.026
Yeast
jnk cascadeGO:0007254720.026
negative regulation of hydrolase activityGO:0051346710.026
respiratory tube developmentGO:00303231670.026
morphogenesis of a branching epitheliumGO:00611381930.026
vesicle localizationGO:0051648860.026
mitotic cell cycleGO:00002781950.026
multi multicellular organism processGO:00447061090.026
notch signaling pathwayGO:0007219710.025
negative regulation of phosphorylationGO:00423261660.025
brain segmentationGO:003528430.025
olfactory learningGO:000835520.025
positive regulation of cellular component biogenesisGO:0044089940.025
cellular response to peptide hormone stimulusGO:0071375920.025
response to lipopolysaccharideGO:00324961280.025
telencephalon developmentGO:00215371860.025
cognitionGO:00508901490.024
fertilizationGO:00095661270.024
regulation of lymphocyte proliferationGO:00506701170.024
protein autophosphorylationGO:0046777610.024
Human
positive regulation of map kinase activityGO:0043406840.024
Human Yeast Mouse Rat Worm
oogenesisGO:0048477560.023
Fly
positive regulation of hydrolase activityGO:00513451480.023
myotube differentiationGO:00149021050.023
regulation of neuron deathGO:19012141340.023
response to ischemiaGO:0002931140.023
retina development in camera type eyeGO:00600411190.023
negative regulation of cell migrationGO:0030336590.023
response to peptide hormoneGO:00434341270.023
negative regulation of apoptotic signaling pathwayGO:20012341040.023
response to nutrient levelsGO:00316671090.023
leukocyte differentiationGO:00025213420.023
epidermis morphogenesisGO:0048730330.023
oocyte developmentGO:0048599330.023
cytokine productionGO:00018163190.023
regulation of neuron projection developmentGO:00109751690.023
regulation of gtp catabolic processGO:00331241130.023
regulation of neurotransmitter transportGO:0051588350.022
nucleocytoplasmic transportGO:00069131390.022
Yeast
placenta developmentGO:00018901400.022
Mouse
peptidyl tyrosine dephosphorylationGO:0035335230.022
Mouse
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744120.022
negative regulation of nucleotide catabolic processGO:003081290.022
cellular response to dna damage stimulusGO:00069742070.022
smooth muscle contractionGO:0006939440.022
response to hypoxiaGO:0001666580.022
regulation of secretionGO:00510462740.021
negative regulation of phosphorus metabolic processGO:00105631840.021
nuclear divisionGO:00002801580.021
regulation of protein maturationGO:1903317960.021
regulation of protein processingGO:0070613960.021
regulation of cytoskeleton organizationGO:00514931220.021
t cell activationGO:00421102890.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.021
cellular senescenceGO:0090398110.021
nucleoside monophosphate metabolic processGO:0009123850.021
gland developmentGO:00487323300.021
regulation of apoptotic signaling pathwayGO:20012331970.021
rap protein signal transductionGO:003248630.021
cellular response to external stimulusGO:0071496880.020
response to reactive oxygen speciesGO:0000302560.020
regulation of anatomical structure sizeGO:00900661780.020
microtubule based movementGO:0007018840.020
regulation of mitotic cell cycleGO:00073461260.020
response to growth factorGO:00708481980.020
protein localization to membraneGO:00726571080.020
positive t cell selectionGO:0043368230.020
regulation of long term neuronal synaptic plasticityGO:0048169190.020
negative regulation of transferase activityGO:0051348850.020
establishment of protein localization to organelleGO:00725941180.020
Yeast
regulation of t cell proliferationGO:0042129920.020
hematopoietic progenitor cell differentiationGO:00022441430.019
organelle localizationGO:00516401790.019
central nervous system segmentationGO:003528330.019
negative regulation of cell cycleGO:00457861230.019
positive regulation of cell deathGO:00109422240.019
regulation of synaptic vesicle exocytosisGO:2000300110.019
regulation of cell morphogenesis involved in differentiationGO:00107691510.019
peptidyl serine phosphorylationGO:0018105740.018
Human
rna interferenceGO:001624620.018
regulation of myotube differentiationGO:0010830620.018
vesicle organizationGO:0016050600.018
cellular response to hormone stimulusGO:00328701500.018
glycoprotein metabolic processGO:00091001160.018
regulation of multi organism processGO:00439001110.018
Yeast
regulation of reproductive processGO:2000241660.018
Yeast
localization within membraneGO:005166840.018
response to extracellular stimulusGO:00099911270.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.018
carbon catabolite regulation of transcriptionGO:004599040.018
t cell proliferationGO:00420981200.018
single organism cell adhesionGO:00986021560.018
myofibril assemblyGO:0030239340.018
establishment of mitochondrion localizationGO:005165440.018
ubiquitin dependent protein catabolic processGO:00065111290.018
neuromuscular processGO:0050905990.018
morphogenesis of a branching structureGO:00017632030.017
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.017
stress activated protein kinase signaling cascadeGO:0031098810.017
positive regulation of stress activated mapk cascadeGO:0032874480.017
peptidyl lysine modificationGO:0018205770.017
learning or memoryGO:00076111480.017
cd4 positive alpha beta t cell activationGO:0035710450.017
guanosine containing compound catabolic processGO:19010691440.017
organelle assemblyGO:00709251770.017
cellular response to lipidGO:00713961450.017
response to organonitrogen compoundGO:00102432460.017
regulation of neurotransmitter levelsGO:0001505870.017
embryonic organ morphogenesisGO:00485622760.017
extrinsic apoptotic signaling pathwayGO:00971911260.016
labyrinthine layer developmentGO:0060711490.016
Mouse
regulation of cell activationGO:00508652890.016
formation of primary germ layerGO:0001704770.016
regulation of protein localizationGO:00328802310.016
regulation of intracellular transportGO:00323861590.016
negative regulation of cell motilityGO:2000146610.016
peptidyl serine modificationGO:0018209830.016
Human
blood vessel morphogenesisGO:00485142850.016
regulation of cell adhesionGO:00301551540.016
cellular response to ethanolGO:007136130.016
regulation of system processGO:00440572000.016
regulation of cellular component biogenesisGO:00440871810.015
positive regulation of cell substrate adhesionGO:0010811470.015
regulation of translational initiationGO:0006446150.015
organophosphate biosynthetic processGO:00904071220.015
visual learningGO:0008542440.015
cytokine mediated signaling pathwayGO:00192211150.015
cellular protein complex assemblyGO:00436231160.015
regulation of cell projection organizationGO:00313442060.015
positive regulation of cytoskeleton organizationGO:0051495490.015
nuclear importGO:0051170950.015
Yeast
cerebral cortex developmentGO:0021987860.015
activation of adenylate cyclase activityGO:000719040.015
negative regulation of protein maturationGO:1903318790.015
gene silencing by rnaGO:0031047190.015
negative regulation of protein processingGO:0010955790.015
microtubule based transportGO:0010970500.015
meiotic cell cycleGO:00513211220.015
molting cycleGO:0042303900.015
erk1 and erk2 cascadeGO:0070371770.015
Fly
sensory organ morphogenesisGO:00905962420.015
modification dependent macromolecule catabolic processGO:00436321330.015
regulation of synaptic vesicle transportGO:1902803130.014
nucleotide biosynthetic processGO:0009165780.014
cellular response to nutrient levelsGO:0031669640.014
translationGO:0006412930.014
regulation of map kinase activityGO:00434051200.014
Human Yeast Mouse Rat Worm
regulation of membrane potentialGO:00423911920.014
b cell activationGO:00421131610.014
positive regulation of actin filament bundle assemblyGO:0032233110.014
protein processingGO:00164851630.014
calcineurin nfat signaling cascadeGO:003317380.014
epithelial cell developmentGO:00020641590.014
Fly
stress activated mapk cascadeGO:0051403800.014
regulation of striated muscle cell differentiationGO:0051153810.014
protein acylationGO:0043543640.014
fatty acid metabolic processGO:00066311210.014
regulation of notch signaling pathwayGO:0008593350.014
autophagyGO:0006914450.013
Yeast
intraspecies interaction between organismsGO:0051703210.013
protein localization to cell junctionGO:190241430.013
negative regulation of cellular catabolic processGO:0031330470.013
gene silencingGO:0016458380.013
immune response activating signal transductionGO:00027571160.013
lymphocyte proliferationGO:00466511640.013
negative regulation of protein modification processGO:00314001630.013
positive regulation of transcription by galactoseGO:000041110.013
organ growthGO:00352651170.013
endomembrane system organizationGO:00102561470.013
homeostasis of number of cellsGO:00488722100.013
lung developmentGO:00303241640.013
protein maturationGO:00516041760.013
regulation of lipid metabolic processGO:00192161180.013
single organism nuclear importGO:1902593950.013
Yeast
regulation of protein catabolic processGO:00421761080.013
purine nucleoside monophosphate metabolic processGO:0009126810.013
negative regulation of phosphate metabolic processGO:00459361840.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
positive regulation of programmed cell deathGO:00430682180.013
synaptic transmission gabaergicGO:0051932190.013
regulation of inflammatory responseGO:00507271470.013
activation of immune responseGO:00022531380.013
regulation of lymphocyte activationGO:00512492400.012
heart trabecula formationGO:0060347140.012
regulation of ras protein signal transductionGO:00465781140.012
Fly
mesoderm developmentGO:00074981000.012
ribonucleoside monophosphate metabolic processGO:0009161800.012
nucleoside monophosphate catabolic processGO:0009125590.012
chromatin organizationGO:00063252060.012
forebrain developmentGO:00309003020.012
regulation of response to woundingGO:19030341890.012
skin morphogenesisGO:0043589380.012
cytoskeleton dependent intracellular transportGO:0030705500.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.012
proteolysis involved in cellular protein catabolic processGO:00516031470.012
extracellular matrix organizationGO:00301981470.012
adaptive immune responseGO:00022501550.012
response to uvGO:0009411440.012
organelle fissionGO:00482851700.012
lymphocyte mediated immunityGO:00024491390.012
locomotor rhythmGO:004547580.012
ovarian follicle developmentGO:0001541400.012
positive regulation of rap gtpase activityGO:003285430.012
rna processingGO:00063961050.012
renal system developmentGO:00720012250.012
cellular homeostasisGO:00197252400.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
response to oxygen levelsGO:0070482620.011
negative regulation of proteolysisGO:0045861740.011
regulation of erbb signaling pathwayGO:1901184160.011
regulation of peptidase activityGO:0052547960.011
negative regulation of peptidase activityGO:0010466460.011
intracellular protein transportGO:00068862040.011
Yeast
cardiac muscle tissue developmentGO:00487381300.011
inflammatory responseGO:00069542440.011
immune effector processGO:00022523210.011
positive regulation of activin receptor signaling pathwayGO:003292730.011
glucose homeostasisGO:00425931280.011
regulation of myeloid leukocyte differentiationGO:0002761580.011
protein targetingGO:00066051430.011
Yeast
striated muscle myosin thick filament assemblyGO:007168810.011
blood circulationGO:00080151950.011
negative regulation of epithelial cell proliferationGO:0050680640.011
response to peptideGO:19016521360.011
response to insulinGO:00328681000.011
positive regulation of immune effector processGO:00026991070.011
purine ribonucleoside monophosphate metabolic processGO:0009167800.011
receptor mediated endocytosisGO:0006898510.011
stem cell maintenanceGO:00198271300.011
internal protein amino acid acetylationGO:0006475420.011
embryonic axis specificationGO:0000578300.011
Fly
synaptic transmissionGO:00072683290.011
dephosphorylationGO:00163111290.011
Mouse
intermediate filament cytoskeleton organizationGO:0045104260.011
regulation of nucleotide metabolic processGO:00061401690.011
pallium developmentGO:00215431200.011
t cell differentiationGO:00302171740.011
positive regulation of defense responseGO:00313491240.011
myosin filament assemblyGO:003103420.011

Map2k2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.027
nervous system diseaseDOID:86300.026
disease of anatomical entityDOID:700.026
cancerDOID:16200.019
organ system cancerDOID:005068600.019
muscle tissue diseaseDOID:6600.016
musculoskeletal system diseaseDOID:1700.016
muscular diseaseDOID:008000000.016
myopathyDOID:42300.014
central nervous system diseaseDOID:33100.014
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012