Mus musculus

134 known processes

Map2k1

mitogen-activated protein kinase kinase 1

(Aliases: MEKK1,Prkmk1,Mek1,MAPKK1)

Map2k1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytoplasmic transportGO:00164822340.219
Yeast
actin cytoskeleton organizationGO:00300362200.195
Yeast
cellular amino acid metabolic processGO:00065201030.171
response to osmotic stressGO:0006970210.171
Yeast
regulation of mapk cascadeGO:00434082480.164
synaptic transmissionGO:00072683290.143
nucleoside phosphate metabolic processGO:00067533380.142
Rat
peptidyl amino acid modificationGO:00181933360.140
amine metabolic processGO:0009308450.139
mapk cascadeGO:00001652810.136
regulation of cellular amino acid metabolic processGO:000652150.133
regionalizationGO:00030023370.123
Fly
cellular amine metabolic processGO:0044106440.123
positive regulation of cellular amino acid metabolic processGO:004576430.120
ras protein signal transductionGO:0007265770.117
Rat Worm Fly
positive regulation of cellular amine metabolic processGO:003324050.116
protein catabolic processGO:00301632210.111
Worm
regulation of protein kinase activityGO:00458592320.109
cation transportGO:00068123990.109
peptidyl serine modificationGO:0018209830.106
regulation of cellular amine metabolic processGO:0033238200.103
regulation of cellular ketone metabolic processGO:0010565660.101
small gtpase mediated signal transductionGO:0007264970.100
Rat Worm Fly
apoptotic signaling pathwayGO:00971903060.097
negative regulation of molecular functionGO:00440922580.094
peptidyl serine phosphorylationGO:0018105740.093
regulation of synaptic plasticityGO:0048167870.092
cellular ketone metabolic processGO:0042180840.089
nucleobase containing small molecule metabolic processGO:00550863520.087
Rat
regulation of apoptotic signaling pathwayGO:20012331970.087
protein modification by small protein conjugationGO:00324461870.087
regulation of cell cycleGO:00517262810.085
Human
cellular protein catabolic processGO:00442571550.084
actin filament organizationGO:00070151130.084
Yeast
purine nucleoside metabolic processGO:00422782410.083
Rat
olfactory learningGO:000835520.082
purine ribonucleoside metabolic processGO:00461282410.081
Rat
positive regulation of protein phosphorylationGO:00019342420.081
intracellular protein transportGO:00068862040.080
Yeast
negative regulation of synaptic vesicle transportGO:190280430.080
regulation of cellular response to stressGO:00801351590.080
Yeast
nucleoside metabolic processGO:00091162460.079
Rat
regulation of synaptic growth at neuromuscular junctionGO:000858240.077
autophagyGO:0006914450.076
Yeast
regulation of organelle organizationGO:00330432890.071
leukocyte differentiationGO:00025213420.071
regulation of secretion by cellGO:19035302490.070
regulation of protein serine threonine kinase activityGO:00719001570.070
inorganic ion transmembrane transportGO:00986602340.070
regulation of transpositionGO:001052820.070
Yeast
regulation of exocytosisGO:0017157610.069
cellular homeostasisGO:00197252400.067
ion transmembrane transportGO:00342203610.067
nucleoside catabolic processGO:00091642060.067
Rat
negative regulation of intracellular signal transductionGO:19025321670.066
muscle system processGO:00030121410.065
Rat
positive regulation of protein modification processGO:00314012990.065
regulation of intracellular transportGO:00323861590.065
calcium ion homeostasisGO:00550741270.064
cellular ion homeostasisGO:00068731650.064
cation homeostasisGO:00550802120.064
organelle localizationGO:00516401790.064
Rat
heterocycle catabolic processGO:00467002800.063
Rat
cell type specific apoptotic processGO:00972852680.063
metal ion homeostasisGO:00550651890.063
establishment of organelle localizationGO:00516561220.062
Rat
positive regulation of organelle organizationGO:00106381280.062
nucleoside triphosphate metabolic processGO:00091412300.062
Rat
cell growthGO:00160491300.061
Yeast
regulation of map kinase activityGO:00434051200.061
myotube differentiationGO:00149021050.060
positive regulation of mapk cascadeGO:00434101700.059
pole plasm assemblyGO:000731520.059
endocytosisGO:00068971680.059
erk1 and erk2 cascadeGO:0070371770.059
Fly
locomotory behaviorGO:00076261950.059
cellular macromolecule catabolic processGO:00442652060.058
macromolecule catabolic processGO:00090572810.057
Worm
learning or memoryGO:00076111480.057
regulation of neuron differentiationGO:00456642810.057
axonogenesisGO:00074092740.056
protein autophosphorylationGO:0046777610.056
regulation of transferase activityGO:00513382630.056
regulation of actin cytoskeleton organizationGO:0032956840.055
aromatic compound catabolic processGO:00194392860.055
Rat
muscle contractionGO:00069361010.055
Rat
regulation of cellular catabolic processGO:00313292420.055
Rat
divalent inorganic cation transportGO:00725111780.054
regulation of secretionGO:00510462740.054
cellular protein complex assemblyGO:00436231160.053
proteolysis involved in cellular protein catabolic processGO:00516031470.053
learningGO:0007612980.052
muscle cell differentiationGO:00426922610.052
associative learningGO:0008306610.052
peptidyl serine autophosphorylationGO:003628910.051
actin polymerization or depolymerizationGO:0008154540.051
establishment of protein localization to organelleGO:00725941180.050
Yeast
neuron apoptotic processGO:00514021420.050
ribonucleoside catabolic processGO:00424542060.049
Rat
nucleocytoplasmic transportGO:00069131390.049
Yeast
positive regulation of erk1 and erk2 cascadeGO:0070374470.049
Fly
protein modification by small protein conjugation or removalGO:00706472070.049
cellular lipid metabolic processGO:00442553230.048
glycosyl compound catabolic processGO:19016582060.048
Rat
regulation of erk1 and erk2 cascadeGO:0070372710.048
Fly
spermatogenesisGO:00072832840.047
protein ubiquitinationGO:00165671710.047
regulation of cell motilityGO:20001452360.047
Mouse Rat
negative regulation of cellular component organizationGO:00511291940.047
exocytosisGO:00068871210.046
positive regulation of kinase activityGO:00336741550.046
sensory perceptionGO:00076002450.045
cognitionGO:00508901490.045
muscle tissue developmentGO:00605373080.045
actomyosin structure organizationGO:0031032560.045
t cell activationGO:00421102890.045
regulation of protein localizationGO:00328802310.045
positive regulation of nervous system developmentGO:00519622210.045
regulation of cellular component biogenesisGO:00440871810.045
divalent metal ion transportGO:00708381720.045
neurotransmitter secretionGO:0007269620.044
regulation of homeostatic processGO:00328441820.044
response to radiationGO:00093141650.044
calcium ion transportGO:00068161590.044
cellular metal ion homeostasisGO:00068751510.044
neuron deathGO:00709971540.044
establishment of vesicle localizationGO:0051650810.044
Rat
long term synaptic potentiationGO:0060291250.044
negative regulation of synaptic vesicle exocytosisGO:200030130.043
oocyte axis specificationGO:000730920.043
positive regulation of cell developmentGO:00107202370.043
zygotic determination of anterior posterior axis embryoGO:000735430.043
Fly
regulation of actin filament lengthGO:0030832450.042
regulation of cell cycle processGO:00105641600.041
purine ribonucleoside triphosphate metabolic processGO:00092052200.041
Rat
ribose phosphate metabolic processGO:00196932910.041
Rat
single organism cell adhesionGO:00986021560.041
Rat
purine ribonucleotide catabolic processGO:00091542080.041
Rat
cellular nitrogen compound catabolic processGO:00442702800.041
Rat
nucleotide metabolic processGO:00091173320.040
Rat
protein processingGO:00164851630.040
vesicle localizationGO:0051648860.040
Rat
intrinsic apoptotic signaling pathwayGO:00971931320.040
regulation of cell migrationGO:00303342190.040
Rat
cell junction maintenanceGO:003433140.040
mitotic cell cycleGO:00002781950.040
Rat
cellular chemical homeostasisGO:00550822150.039
regulation of defense responseGO:00313472330.039
regulation of actin filament based processGO:0032970990.039
regulation of ras protein signal transductionGO:00465781140.039
Rat Fly
response to molecule of bacterial originGO:00022371430.039
nitrogen compound transportGO:00717052710.039
membrane organizationGO:00610242450.039
immune effector processGO:00022523210.038
regulation of cytoplasmic transportGO:19036491120.038
nuclear transportGO:00511691390.038
Yeast
oocyte anterior posterior axis specificationGO:000731420.038
transmembrane transportGO:00550854120.038
ribonucleoside triphosphate catabolic processGO:00092031990.038
Rat
nucleotide catabolic processGO:00091662170.038
Rat
purine nucleoside triphosphate catabolic processGO:00091462030.037
Rat
ubiquitin dependent protein catabolic processGO:00065111290.037
divalent inorganic cation homeostasisGO:00725071380.037
regulation of kinase activityGO:00435492490.037
regulation of neuron apoptotic processGO:00435231220.037
protein localization to organelleGO:00333651850.037
Yeast
segmentationGO:0035282930.036
Fly
regulation of cytoskeleton organizationGO:00514931220.036
germ cell developmentGO:00072811850.036
Fly
homeostasis of number of cellsGO:00488722100.036
purine nucleotide catabolic processGO:00061952110.036
Rat
cation transmembrane transportGO:00986552660.036
regulation of intracellular protein transportGO:0033157820.036
positive regulation of protein serine threonine kinase activityGO:00719021060.035
muscle cell developmentGO:00550011330.035
organic cyclic compound catabolic processGO:19013612950.035
Rat
regulation of hydrolase activityGO:00513362460.035
Rat
epidermis developmentGO:00085441870.035
negative regulation of neuron deathGO:1901215980.035
cytokine productionGO:00018163190.035
multi multicellular organism processGO:00447061090.035
male gamete generationGO:00482322850.035
cellular divalent inorganic cation homeostasisGO:00725031270.034
skin developmentGO:00435882200.034
striated muscle tissue developmentGO:00147062930.034
maintenance of locationGO:0051235890.034
sequestering of calcium ionGO:0051208180.034
cellular response to abiotic stimulusGO:0071214560.033
Yeast
modification dependent protein catabolic processGO:00199411330.033
regulation of cell projection organizationGO:00313442060.033
inorganic cation transmembrane transportGO:00986622070.033
organelle assemblyGO:00709251770.033
negative regulation of protein metabolic processGO:00512482820.033
lymphocyte differentiationGO:00300982420.032
regulation of cellular component sizeGO:00325351210.032
ribonucleoside metabolic processGO:00091192450.032
Rat
leukocyte mediated immunityGO:00024431740.032
response to extracellular stimulusGO:00099911270.032
positive regulation of transferase activityGO:00513471670.032
cellular calcium ion homeostasisGO:00068741190.032
regulation of muscle system processGO:0090257800.032
Rat
inflammatory responseGO:00069542440.032
alpha beta t cell differentiationGO:0046632690.032
response to inorganic substanceGO:0010035960.032
peptidyl tyrosine phosphorylationGO:00181081430.031
oocyte constructionGO:000730820.031
regulation of synaptic vesicle exocytosisGO:2000300110.031
actin filament polymerizationGO:0030041440.031
dephosphorylationGO:00163111290.031
positive regulation of apoptotic processGO:00430652170.031
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.031
positive regulation of cell deathGO:00109422240.031
extracellular matrix organizationGO:00301981470.031
regulation of cell activationGO:00508652890.031
response to light stimulusGO:00094161350.031
organonitrogen compound biosynthetic processGO:19015661920.030
negative regulation of apoptotic signaling pathwayGO:20012341040.030
regulation of mitotic cell cycleGO:00073461260.030
early endosome to late endosome transportGO:004502220.030
positive regulation of proteolysisGO:0045862850.030
carbohydrate derivative biosynthetic processGO:19011371830.030
t cell differentiationGO:00302171740.030
response to oxidative stressGO:00069791230.030
Rat
engulfment of apoptotic cellGO:004365230.030
positive regulation of protein kinase activityGO:00458601440.030
response to lipopolysaccharideGO:00324961280.030
regulation of actin filament polymerizationGO:0030833380.030
protein polymerizationGO:0051258570.030
regulation of proteolysisGO:00301621640.029
mitotic cell cycle processGO:19030471590.029
Rat
positive regulation of programmed cell deathGO:00430682180.029
rhythmic processGO:00485111740.029
protein maturationGO:00516041760.029
negative regulation of phosphate metabolic processGO:00459361840.029
response to organonitrogen compoundGO:00102432460.029
amide transportGO:00428861380.029
developmental maturationGO:00217001930.029
adherens junction maintenanceGO:003433410.029
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
Rat
regulation of neuron deathGO:19012141340.029
g protein coupled receptor signaling pathwayGO:00071862430.029
Yeast
wound healingGO:00420601570.028
endomembrane system organizationGO:00102561470.028
Rat
negative regulation of fibroblast migrationGO:001076420.028
meiotic cell cycleGO:00513211220.028
myeloid cell differentiationGO:00300992330.027
sequestering of metal ionGO:0051238190.027
regulation of membrane potentialGO:00423911920.027
regulation of hormone levelsGO:00108172110.027
cell adhesionGO:00071553290.027
Rat
synaptic vesicle localizationGO:0097479590.027
organonitrogen compound catabolic processGO:19015652640.027
Rat
modification dependent macromolecule catabolic processGO:00436321330.027
pigmentationGO:0043473710.027
Rat
retrograde transport endosome to golgiGO:004214720.026
alpha beta t cell activationGO:0046631910.026
protein import into nucleusGO:0006606950.026
Yeast
purine containing compound metabolic processGO:00725213110.026
Rat
nuclear importGO:0051170950.026
Yeast
positive regulation of protein export from nucleusGO:004682740.026
ribonucleoside triphosphate metabolic processGO:00091992200.026
Rat
purine containing compound catabolic processGO:00725232130.026
Rat
dna metabolic processGO:00062593030.026
regulation of vesicle mediated transportGO:00606271390.026
negative regulation of protein phosphorylationGO:00019331260.026
regulation of neurotransmitter levelsGO:0001505870.026
gtp catabolic processGO:00061841430.026
Rat
purine ribonucleotide metabolic processGO:00091502900.025
Rat
anion transportGO:00068201770.025
maternal determination of anterior posterior axis embryoGO:000835820.025
stem cell differentiationGO:00488632680.025
purine nucleotide metabolic processGO:00061633020.025
Rat
adaptive immune responseGO:00022501550.025
regulation of system processGO:00440572000.025
Rat
conditioned taste aversionGO:000166140.025
nucleoside triphosphate catabolic processGO:00091432050.025
Rat
monocarboxylic acid metabolic processGO:00327871910.025
striated muscle cell developmentGO:00550021250.025
positive regulation of map kinase activityGO:0043406840.025
carbohydrate metabolic processGO:00059752300.025
peptide transportGO:00158331330.025
circadian rhythmGO:00076231140.024
wnt signaling pathwayGO:00160551880.024
regulation of protein transportGO:00512231630.024
keratinocyte differentiationGO:0030216480.024
cellular response to external stimulusGO:0071496880.024
dendrite developmentGO:00163581150.024
regulation of cytokine productionGO:00018172660.024
response to organic cyclic compoundGO:00140701980.024
Rat
regulation of synaptic vesicle transportGO:1902803130.024
regulation of cell substrate adhesionGO:0010810730.024
regulation of actin polymerization or depolymerizationGO:0008064450.024
negative regulation of phosphorylationGO:00423261660.023
hormone secretionGO:00468791280.023
positive regulation of cellular component biogenesisGO:0044089940.023
syncytium formation by plasma membrane fusionGO:0000768420.023
extracellular structure organizationGO:00430621480.023
positive regulation of hydrolase activityGO:00513451480.023
Rat
positive regulation of secretion by cellGO:19035321140.023
oxidation reduction processGO:00551143420.023
positive regulation of lymphocyte activationGO:00512511400.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.023
single organism nuclear importGO:1902593950.023
Yeast
regulation of establishment of protein localizationGO:00702011810.023
telencephalon developmentGO:00215371860.023
negative regulation of cell proliferationGO:00082852960.023
Human
positive regulation of cytoskeleton organizationGO:0051495490.023
cell substrate adhesionGO:00315891300.023
gland developmentGO:00487323300.023
peptidyl tyrosine modificationGO:00182121450.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.022
regulation of ion transportGO:00432692150.022
immune response activating signal transductionGO:00027571160.022
barbed end actin filament cappingGO:005101660.022
digestive system developmentGO:00551232000.022
regulation of neuron projection developmentGO:00109751690.022
activation of immune responseGO:00022531380.022
regulation of multi organism processGO:00439001110.022
Yeast
protein localization to vacuoleGO:007266540.022
embryonic organ morphogenesisGO:00485622760.022
regulation of circadian sleep wake cycleGO:004274930.022
cell maturationGO:00484691270.022
protein importGO:00170381010.022
Yeast
synapse organizationGO:00508081250.022
stress activated protein kinase signaling cascadeGO:0031098810.022
negative regulation of phosphorus metabolic processGO:00105631840.022
positive regulation of neuron differentiationGO:00456661410.022
cellular response to organonitrogen compoundGO:00714171450.022
negative regulation of cell developmentGO:00107211690.022
regulation of protein catabolic processGO:00421761080.022
striated muscle myosin thick filament assemblyGO:007168810.022
regulation of response to woundingGO:19030341890.022
social behaviorGO:0035176210.022
cellular response to biotic stimulusGO:0071216920.021
positive regulation of protein transportGO:0051222930.021
cytosolic calcium ion transportGO:0060401480.021
establishment or maintenance of cytoskeleton polarityGO:003095220.021
protein targetingGO:00066051430.021
Yeast
negative regulation of secretionGO:0051048610.021
negative regulation of transferase activityGO:0051348850.021
ribonucleotide metabolic processGO:00092592910.021
Rat
neurotransmitter transportGO:0006836760.021
immune response regulating signaling pathwayGO:00027641250.021
regulation of protein complex assemblyGO:0043254830.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
rac protein signal transductionGO:0016601130.021
regulation of postsynaptic membrane potentialGO:0060078480.021
carbohydrate derivative catabolic processGO:19011362310.021
Rat
lymphocyte mediated immunityGO:00024491390.021
cellular response to lipopolysaccharideGO:0071222770.021
guanosine containing compound metabolic processGO:19010681440.021
Rat
defense response to bacteriumGO:00427421190.020
myosin filament organizationGO:003103330.020
jnk cascadeGO:0007254720.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
Rat
gastrulationGO:00073691160.020
heart contractionGO:0060047930.020
organophosphate catabolic processGO:00464342320.020
Rat
placenta developmentGO:00018901400.020
purine ribonucleoside catabolic processGO:00461302050.020
Rat
insulin secretionGO:0030073890.020
organic hydroxy compound metabolic processGO:19016152030.020
cellular response to hormone stimulusGO:00328701500.020
striated muscle contractionGO:0006941450.020
positive regulation of macrophage derived foam cell differentiationGO:001074440.020
glucose homeostasisGO:00425931280.020
negative regulation of cellular protein metabolic processGO:00322692470.020
epithelial cell proliferationGO:00506731740.020
organic acid transportGO:00158491010.020
carbohydrate homeostasisGO:00335001280.020
innate immune responseGO:00450871570.020
organophosphate biosynthetic processGO:00904071220.020
response to nutrient levelsGO:00316671090.020
membrane fusionGO:0061025380.019
neuromuscular processGO:0050905990.019
sodium ion transportGO:0006814730.019
regulation of neurotransmitter transportGO:0051588350.019
chemotaxisGO:00069352470.019
activation of mapk activityGO:0000187590.019
visual learningGO:0008542440.019
lipid localizationGO:00108761260.019
canonical wnt signaling pathwayGO:00600701300.019
multi organism behaviorGO:0051705620.019
negative regulation of kinase activityGO:0033673810.019
adult behaviorGO:00305341350.019
calcium ion transmembrane transportGO:0070588850.019
hyperosmotic responseGO:000697240.019
Yeast
blood vessel morphogenesisGO:00485142850.019
fertilizationGO:00095661270.019
development of primary sexual characteristicsGO:00451371430.019
Worm
nucleoside monophosphate metabolic processGO:0009123850.019
cell activation involved in immune responseGO:00022631260.019
regulation of cell adhesionGO:00301551540.019
Rat
regulation of sequence specific dna binding transcription factor activityGO:00510901060.018
positive regulation of cell projection organizationGO:0031346950.018
cellular response to osmotic stressGO:007147070.018
Yeast
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.018
cellular component assembly involved in morphogenesisGO:00109271390.018
response to oxygen levelsGO:0070482620.018
microtubule based movementGO:0007018840.018
Rat
regulation of cell divisionGO:0051302760.018
neuron projection extensionGO:1990138640.018
positive regulation of secretionGO:00510471300.018
organic anion transportGO:00157111370.018
regulation of neurotransmitter secretionGO:0046928290.018
ribonucleoside monophosphate metabolic processGO:0009161800.018
negative regulation of nervous system developmentGO:00519611560.018
negative regulation of protein modification processGO:00314001630.018
gliogenesisGO:00420631410.018
regulation of nucleocytoplasmic transportGO:0046822730.018
developmental cell growthGO:0048588840.018
extrinsic apoptotic signaling pathwayGO:00971911260.018
rap protein signal transductionGO:003248630.018
cellular response to dna damage stimulusGO:00069742070.018
regulation of anatomical structure sizeGO:00900661780.018
Rat
response to peptideGO:19016521360.018
compound eye developmentGO:004874910.018
protein complex disassemblyGO:0043241400.018
negative regulation of neuron apoptotic processGO:0043524920.018
positive regulation of cytokine productionGO:00018191740.018
establishment of synaptic vesicle localizationGO:0097480570.018
lipid transportGO:0006869980.018
b cell activationGO:00421131610.018
peptide hormone secretionGO:00300721090.018
reactive nitrogen species metabolic processGO:200105700.017
heart processGO:0003015940.017
regulation of jnk cascadeGO:0046328620.017
regulation of transporter activityGO:0032409570.017
ameboidal type cell migrationGO:00016671280.017
Fly
regulation of ion transmembrane transporter activityGO:0032412540.017
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.017
cd4 positive alpha beta t cell activationGO:0035710450.017
negative regulation of protein serine threonine kinase activityGO:0071901490.017
digestive tract morphogenesisGO:00485461470.017
arp2 3 complex mediated actin nucleationGO:003431430.017
regulation of neuronal synaptic plasticityGO:0048168300.017
release of sequestered calcium ion into cytosolGO:0051209420.017
angiogenesisGO:00015252010.017
protein oligomerizationGO:0051259670.017
Rat
negative regulation of organelle organizationGO:0010639900.017
skeletal muscle organ developmentGO:00605381630.017
glycosylationGO:0070085620.017
regulation of inflammatory responseGO:00507271470.017
cytosolic calcium ion homeostasisGO:0051480700.017
response to reactive oxygen speciesGO:0000302560.017
actin filament bundle assemblyGO:0051017400.017
cellular response to extracellular stimulusGO:0031668810.017
cell recognitionGO:0008037830.017
cellular response to cadmium ionGO:007127630.017
negative regulation of homeostatic processGO:0032845710.017
leukocyte proliferationGO:00706611720.017
regulation of stress activated mapk cascadeGO:0032872690.016
response to metal ionGO:0010038470.016
fibroblast migrationGO:0010761210.016
regulation of mitotic cell cycle phase transitionGO:1901990730.016
positive regulation of t cell activationGO:00508701010.016
p38mapk cascadeGO:003806640.016
nucleoside phosphate biosynthetic processGO:1901293790.016
regulation of ion homeostasisGO:2000021640.016
positive regulation of peptide hormone secretionGO:0090277310.016
multicellular organism growthGO:00352641610.016
camera type eye developmentGO:00430102660.016
response to starvationGO:0042594650.016
stress activated mapk cascadeGO:0051403800.016
neuromuscular process controlling balanceGO:0050885590.016
activation of mapkkk activityGO:000018510.016
negative regulation of map kinase activityGO:0043407340.016
regulation of nuclear divisionGO:0051783560.016
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.016
purine nucleoside catabolic processGO:00061522050.016
Rat
myeloid cell homeostasisGO:00022621140.016
regulation of peptide transportGO:0090087910.016
macromolecular complex disassemblyGO:0032984430.016
single fertilizationGO:0007338820.016
cellular response to acid chemicalGO:0071229680.016
positive regulation of cell migrationGO:00303351090.016
Rat
positive regulation of leukocyte differentiationGO:1902107860.016
atp catabolic processGO:0006200550.015
neuron neuron synaptic transmissionGO:0007270690.015
alcohol metabolic processGO:00060661160.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.015
microtubule based processGO:00070172360.015
Rat
negative regulation of synapse assemblyGO:005196430.015
glutamate receptor signaling pathwayGO:0007215350.015
hematopoietic progenitor cell differentiationGO:00022441430.015
nucleotide biosynthetic processGO:0009165780.015
atp metabolic processGO:0046034750.015
regulation of response to drugGO:200102320.015
negative regulation of hydrolase activityGO:0051346710.015
cellular protein complex disassemblyGO:0043624360.015
regulation of circadian rhythmGO:0042752580.015

Map2k1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.028
musculoskeletal system diseaseDOID:1700.022
connective tissue diseaseDOID:6500.019