| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.644 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.483 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.405 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.349 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.285 | Zebrafish Mouse Rat Worm Fly |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.268 | Zebrafish Mouse Rat Worm Fly |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.264 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.263 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.245 | Zebrafish Mouse Rat Worm Fly |
| ras protein signal transduction | GO:0007265 | 77 | 0.243 | |
| protein localization to organelle | GO:0033365 | 185 | 0.233 | |
| protein ubiquitination | GO:0016567 | 171 | 0.218 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.217 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.215 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.209 | Zebrafish Mouse Rat Worm Fly |
| protein catabolic process | GO:0030163 | 221 | 0.196 | |
| intracellular protein transport | GO:0006886 | 204 | 0.195 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.191 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.191 | Zebrafish Mouse Rat Fly |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.187 | Zebrafish Mouse Rat Worm Fly |
| peptidyl serine modification | GO:0018209 | 83 | 0.180 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.179 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.176 | Rat |
| negative regulation of molecular function | GO:0044092 | 258 | 0.170 | |
| jnk cascade | GO:0007254 | 72 | 0.166 | Zebrafish Mouse Rat Fly |
| mitochondrion organization | GO:0007005 | 134 | 0.163 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.159 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.153 | Zebrafish Mouse Rat Fly |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.151 | Zebrafish Mouse Rat Worm Fly |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.147 | Zebrafish Mouse Rat Worm Fly |
| regulation of proteolysis | GO:0030162 | 164 | 0.145 | |
| autophagy | GO:0006914 | 45 | 0.142 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.132 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.131 | |
| protein targeting | GO:0006605 | 143 | 0.129 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.120 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.115 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.114 | |
| mitochondrion distribution | GO:0048311 | 4 | 0.114 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.113 | |
| response to osmotic stress | GO:0006970 | 21 | 0.110 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.108 | |
| negative regulation of ripoptosome assembly involved in necroptotic process | GO:1902443 | 3 | 0.106 | |
| synaptic transmission | GO:0007268 | 329 | 0.103 | Worm |
| regulation of jnk cascade | GO:0046328 | 62 | 0.100 | Zebrafish Mouse Rat Fly |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.099 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.098 | |
| protein import into nucleus | GO:0006606 | 95 | 0.095 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.094 | |
| cation transport | GO:0006812 | 399 | 0.093 | |
| mapk cascade | GO:0000165 | 281 | 0.090 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.090 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.090 | Zebrafish Mouse Rat Worm Fly |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.089 | |
| protein import | GO:0017038 | 101 | 0.089 | |
| p38mapk cascade | GO:0038066 | 4 | 0.088 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.087 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.087 | |
| membrane organization | GO:0061024 | 245 | 0.085 | |
| dephosphorylation | GO:0016311 | 129 | 0.085 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.082 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.082 | |
| regulation of protein localization | GO:0032880 | 231 | 0.081 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.080 | Rat |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.079 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.079 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.076 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.076 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.076 | Zebrafish Mouse Rat Worm Fly |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.076 | Zebrafish Mouse Rat Fly |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.075 | Zebrafish Mouse Rat Worm Fly |
| myotube differentiation | GO:0014902 | 105 | 0.074 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.073 | Rat |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.073 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.073 | |
| response to growth factor | GO:0070848 | 198 | 0.073 | |
| muscle tissue development | GO:0060537 | 308 | 0.072 | Rat |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.071 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.071 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.070 | |
| endocytosis | GO:0006897 | 168 | 0.070 | |
| dna metabolic process | GO:0006259 | 303 | 0.070 | Rat |
| cellular protein complex assembly | GO:0043623 | 116 | 0.069 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.068 | |
| protein oligomerization | GO:0051259 | 67 | 0.067 | |
| single organism nuclear import | GO:1902593 | 95 | 0.065 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.065 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.065 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.065 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.065 | |
| striated muscle cell development | GO:0055002 | 125 | 0.064 | Rat |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.063 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.063 | Rat |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.061 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.059 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.059 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.059 | |
| organelle localization | GO:0051640 | 179 | 0.059 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.059 | |
| axonogenesis | GO:0007409 | 274 | 0.058 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.057 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.057 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.056 | |
| regulation of secretion | GO:0051046 | 274 | 0.056 | |
| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 0.056 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.055 | |
| positive regulation of jun kinase activity | GO:0043507 | 30 | 0.055 | Zebrafish Mouse Rat Fly |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.054 | Zebrafish Mouse Rat Worm Fly |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.053 | |
| nuclear transport | GO:0051169 | 139 | 0.053 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.053 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.053 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.053 | |
| compound eye development | GO:0048749 | 1 | 0.053 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.052 | |
| regulation of cell migration | GO:0030334 | 219 | 0.052 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.051 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.051 | |
| organelle fission | GO:0048285 | 170 | 0.051 | |
| regulation of wnt signaling pathway | GO:0030111 | 123 | 0.051 | |
| digestive tract development | GO:0048565 | 190 | 0.051 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.051 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.051 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.051 | |
| amine metabolic process | GO:0009308 | 45 | 0.050 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.050 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.050 | Rat |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.049 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.049 | |
| vacuole organization | GO:0007033 | 38 | 0.049 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.049 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.048 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.047 | |
| histone modification | GO:0016570 | 159 | 0.047 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.047 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.047 | |
| necrotic cell death | GO:0070265 | 30 | 0.047 | |
| cell division | GO:0051301 | 120 | 0.047 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.047 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.046 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.046 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.046 | |
| regionalization | GO:0003002 | 337 | 0.046 | Zebrafish |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 0.046 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.045 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.045 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.045 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.045 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.045 | |
| phagocytosis | GO:0006909 | 66 | 0.045 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.045 | Zebrafish Mouse Rat Worm Fly |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.044 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.044 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.044 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.044 | Human |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.044 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.043 | |
| regulation of cell motility | GO:2000145 | 236 | 0.043 | |
| nuclear import | GO:0051170 | 95 | 0.043 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.043 | Human |
| wound healing | GO:0042060 | 157 | 0.043 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.043 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.042 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.042 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.042 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.042 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.042 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.042 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.041 | |
| activation of mapkk activity | GO:0000186 | 15 | 0.041 | |
| protein polymerization | GO:0051258 | 57 | 0.041 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.041 | |
| microtubule based movement | GO:0007018 | 84 | 0.041 | |
| protein maturation | GO:0051604 | 176 | 0.041 | |
| digestive system development | GO:0055123 | 200 | 0.041 | |
| exocytosis | GO:0006887 | 121 | 0.041 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.041 | |
| muscle cell development | GO:0055001 | 133 | 0.040 | Rat |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.040 | |
| gtp metabolic process | GO:0046039 | 144 | 0.039 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.039 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.038 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.038 | |
| vesicle localization | GO:0051648 | 86 | 0.038 | |
| response to uv | GO:0009411 | 44 | 0.038 | |
| regulation of engulfment of apoptotic cell | GO:1901074 | 2 | 0.038 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.037 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.037 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.037 | |
| peptidyl threonine modification | GO:0018210 | 31 | 0.036 | |
| protein processing | GO:0016485 | 163 | 0.036 | |
| regulation of system process | GO:0044057 | 200 | 0.036 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.036 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.036 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.036 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.036 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.036 | |
| meiotic nuclear division | GO:0007126 | 115 | 0.035 | |
| muscle system process | GO:0003012 | 141 | 0.035 | Mouse Rat |
| rhythmic process | GO:0048511 | 174 | 0.035 | |
| activation of jnkk activity | GO:0007256 | 3 | 0.035 | |
| positive regulation of protein import into nucleus | GO:0042307 | 26 | 0.035 | |
| activation of jun kinase activity | GO:0007257 | 15 | 0.035 | Zebrafish Mouse Rat Fly |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.035 | |
| muscle contraction | GO:0006936 | 101 | 0.035 | Mouse |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.034 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.034 | |
| response to oxidative stress | GO:0006979 | 123 | 0.034 | |
| cognition | GO:0050890 | 149 | 0.034 | |
| osmosensory signaling pathway | GO:0007231 | 1 | 0.034 | |
| olfactory learning | GO:0008355 | 2 | 0.033 | |
| lipid modification | GO:0030258 | 65 | 0.033 | |
| microtubule based process | GO:0007017 | 236 | 0.033 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.033 | |
| actin filament organization | GO:0007015 | 113 | 0.033 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.033 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.033 | |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.033 | Zebrafish Mouse Rat Worm Fly |
| response to transforming growth factor beta | GO:0071559 | 88 | 0.033 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.033 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.033 | |
| regulation of protein transport | GO:0051223 | 163 | 0.032 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 71 | 0.032 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.032 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.032 | |
| amide transport | GO:0042886 | 138 | 0.032 | |
| membrane fusion | GO:0061025 | 38 | 0.032 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.032 | |
| hyperosmotic response | GO:0006972 | 4 | 0.032 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.032 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.032 | |
| chromatin modification | GO:0016568 | 187 | 0.031 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.031 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.031 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.031 | |
| skeletal muscle fiber development | GO:0048741 | 58 | 0.031 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.031 | |
| stress activated mapk cascade | GO:0051403 | 80 | 0.031 | Zebrafish Mouse Rat Fly |
| stem cell differentiation | GO:0048863 | 268 | 0.031 | |
| cellular response to arsenic containing substance | GO:0071243 | 4 | 0.030 | |
| neuron death | GO:0070997 | 154 | 0.030 | Rat |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.029 | Zebrafish Mouse Rat Fly |
| response to peptide | GO:1901652 | 136 | 0.029 | |
| peptide transport | GO:0015833 | 133 | 0.029 | |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.029 | Zebrafish Mouse Rat Fly |
| locomotory behavior | GO:0007626 | 195 | 0.029 | |
| respiratory system development | GO:0060541 | 190 | 0.029 | |
| gastrulation | GO:0007369 | 116 | 0.028 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.028 | |
| meiotic cell cycle process | GO:1903046 | 77 | 0.028 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.028 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.027 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.027 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.027 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.027 | |
| developmental maturation | GO:0021700 | 193 | 0.027 | Fly |
| skeletal muscle organ development | GO:0060538 | 163 | 0.027 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.027 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.027 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.027 | |
| inositol phosphate catabolic process | GO:0071545 | 4 | 0.027 | |
| lateral inhibition | GO:0046331 | 1 | 0.027 | |
| synapse organization | GO:0050808 | 125 | 0.027 | Worm |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.026 | |
| gtp catabolic process | GO:0006184 | 143 | 0.026 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.026 | |
| oogenesis | GO:0048477 | 56 | 0.026 | |
| oocyte axis specification | GO:0007309 | 2 | 0.026 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.026 | |
| female gamete generation | GO:0007292 | 74 | 0.026 | |
| microtubule based transport | GO:0010970 | 50 | 0.026 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.026 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.026 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.026 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.026 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.026 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.025 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.025 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.025 | |
| chromatin organization | GO:0006325 | 206 | 0.025 | |
| stem cell development | GO:0048864 | 219 | 0.025 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.025 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.025 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.025 | |
| regulation of peptide transport | GO:0090087 | 91 | 0.025 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.025 | |
| macroautophagy | GO:0016236 | 21 | 0.025 | |
| maintenance of location | GO:0051235 | 89 | 0.024 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 88 | 0.024 | |
| neuronal action potential | GO:0019228 | 54 | 0.024 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.024 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.024 | |
| regulation of neuron death | GO:1901214 | 134 | 0.024 | Rat |
| neuron projection extension | GO:1990138 | 64 | 0.024 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.024 | |
| germ cell development | GO:0007281 | 185 | 0.024 | |
| golgi localization | GO:0051645 | 4 | 0.024 | |
| cation homeostasis | GO:0055080 | 212 | 0.024 | |
| pole plasm assembly | GO:0007315 | 2 | 0.024 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.023 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.023 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.023 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 83 | 0.023 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.023 | |
| circadian rhythm | GO:0007623 | 114 | 0.023 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.023 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.023 | |
| positive regulation of cytoskeleton organization | GO:0051495 | 49 | 0.023 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.023 | |
| regulation of defense response | GO:0031347 | 233 | 0.023 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.023 | |
| intra golgi vesicle mediated transport | GO:0006891 | 1 | 0.022 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.022 | |
| cardiac muscle tissue development | GO:0048738 | 130 | 0.022 | Rat |
| syncytium formation | GO:0006949 | 43 | 0.022 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.022 | |
| organelle assembly | GO:0070925 | 177 | 0.022 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.022 | |
| negative regulation of phagocytosis | GO:0050765 | 4 | 0.022 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.022 | Zebrafish Mouse Rat Worm Fly |
| germline cell cycle switching mitotic to meiotic cell cycle | GO:0051729 | 1 | 0.022 | |
| nuclear division | GO:0000280 | 158 | 0.022 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.022 | Worm |
| regulation of ion transport | GO:0043269 | 215 | 0.022 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.022 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.022 | |
| angiogenesis | GO:0001525 | 201 | 0.022 | |
| gland development | GO:0048732 | 330 | 0.021 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 50 | 0.021 | |
| plasma membrane organization | GO:0007009 | 90 | 0.021 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.021 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.021 | |
| transmembrane transport | GO:0055085 | 412 | 0.021 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.021 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.021 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.021 | |
| cellular homeostasis | GO:0019725 | 240 | 0.021 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.021 | |
| fibroblast growth factor receptor signaling pathway | GO:0008543 | 46 | 0.021 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.020 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 48 | 0.020 | Zebrafish Mouse Rat Fly |
| regulation of protein processing | GO:0070613 | 96 | 0.020 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.020 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.020 | |
| meiosis i | GO:0007127 | 60 | 0.020 | |
| synaptic vesicle localization | GO:0097479 | 59 | 0.020 | |
| immune effector process | GO:0002252 | 321 | 0.020 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.020 | |
| cell growth | GO:0016049 | 130 | 0.020 | Rat |
| regulation of response to wounding | GO:1903034 | 189 | 0.020 | |
| positive regulation of growth | GO:0045927 | 104 | 0.020 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.020 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.020 | |
| learning or memory | GO:0007611 | 148 | 0.020 | |
| mitochondrion transport along microtubule | GO:0047497 | 3 | 0.020 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.020 | |
| positive regulation of macroautophagy | GO:0016239 | 3 | 0.020 | |
| cartilage development | GO:0051216 | 140 | 0.020 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 24 | 0.019 | |
| circulatory system process | GO:0003013 | 197 | 0.019 | Mouse |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.019 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.019 | |
| cellular response to osmotic stress | GO:0071470 | 7 | 0.019 | |
| positive regulation of protein complex assembly | GO:0031334 | 45 | 0.019 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.019 | |
| mesoderm development | GO:0007498 | 100 | 0.019 | |
| response to nutrient levels | GO:0031667 | 109 | 0.019 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.019 | |
| determination of left right symmetry | GO:0007368 | 80 | 0.019 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.019 | |
| regulation of striated muscle cell differentiation | GO:0051153 | 81 | 0.019 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.019 | |
| adult behavior | GO:0030534 | 135 | 0.019 | |
| myoblast differentiation involved in skeletal muscle regeneration | GO:0014835 | 3 | 0.019 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.019 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.018 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.018 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.018 | |
| oocyte construction | GO:0007308 | 2 | 0.018 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.018 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.018 | |
| muscle fiber development | GO:0048747 | 76 | 0.018 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.018 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.018 | |
| cellular response to cadmium ion | GO:0071276 | 3 | 0.018 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.018 | |
| lung development | GO:0030324 | 164 | 0.018 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.018 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.018 | |
| camera type eye development | GO:0043010 | 266 | 0.018 | |
| lipid localization | GO:0010876 | 126 | 0.018 | |
| peptide metabolic process | GO:0006518 | 46 | 0.018 | |
| regulation of rho protein signal transduction | GO:0035023 | 71 | 0.018 | |
| cell adhesion | GO:0007155 | 329 | 0.018 | |
| regulation of excitatory postsynaptic membrane potential | GO:0060079 | 41 | 0.017 | |
| myotube cell development | GO:0014904 | 60 | 0.017 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.017 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.017 | |
| cellular response to nitric oxide | GO:0071732 | 4 | 0.017 | |
| regulation of circadian rhythm | GO:0042752 | 58 | 0.017 | |
| formation of primary germ layer | GO:0001704 | 77 | 0.017 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.017 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.017 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.017 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.017 | |
| action potential | GO:0001508 | 78 | 0.017 | |
| defense response to other organism | GO:0098542 | 197 | 0.017 | |
| regulation of muscle tissue development | GO:1901861 | 97 | 0.017 | |
| membrane invagination | GO:0010324 | 17 | 0.017 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.017 | |
| cellular amide metabolic process | GO:0043603 | 58 | 0.017 | |
| negative regulation of jun kinase activity | GO:0043508 | 9 | 0.017 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.017 | Rat |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.017 | |
| negative regulation of necroptotic process | GO:0060546 | 9 | 0.017 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.017 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.017 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.017 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.017 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.017 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.017 | |
| regulation of myotube differentiation | GO:0010830 | 62 | 0.016 | |
| cellular response to inorganic substance | GO:0071241 | 37 | 0.016 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.016 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 36 | 0.016 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.016 | |
| multicellular organism growth | GO:0035264 | 161 | 0.016 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.016 | |
| establishment of mitochondrion localization | GO:0051654 | 4 | 0.016 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.016 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.016 | |
| ameboidal type cell migration | GO:0001667 | 128 | 0.016 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.016 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.016 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.016 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.016 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.016 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.016 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.016 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.016 | |
| dna repair | GO:0006281 | 107 | 0.016 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.016 | |
| cellular response to lipid | GO:0071396 | 145 | 0.016 | |
| response to inorganic substance | GO:0010035 | 96 | 0.016 | |
| oxidation reduction process | GO:0055114 | 342 | 0.016 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.016 | |
| axon ensheathment | GO:0008366 | 76 | 0.016 | |
| regulation of cell activation | GO:0050865 | 289 | 0.016 | |
| positive regulation of necrotic cell death | GO:0010940 | 1 | 0.016 | |
| response to peptide hormone | GO:0043434 | 127 | 0.016 | |
| dendrite development | GO:0016358 | 115 | 0.016 | |
| positive regulation of macrophage derived foam cell differentiation | GO:0010744 | 4 | 0.016 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.016 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.015 | Rat |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.015 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.015 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.015 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.015 | |
| skeletal myofibril assembly | GO:0014866 | 4 | 0.015 | |
| regulation of actin filament length | GO:0030832 | 45 | 0.015 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.015 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.015 | |
| organelle disassembly | GO:1903008 | 2 | 0.015 | |
| negative regulation of necrotic cell death | GO:0060547 | 11 | 0.015 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.015 | |
| midgut development | GO:0007494 | 4 | 0.015 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.015 | |
| viral gene expression | GO:0019080 | 3 | 0.015 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.015 | |
| golgi vesicle transport | GO:0048193 | 30 | 0.015 | |
| cytokine production | GO:0001816 | 319 | 0.015 | Mouse |
| organic anion transport | GO:0015711 | 137 | 0.015 | |
| positive regulation of nfat protein import into nucleus | GO:0051533 | 1 | 0.015 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.015 | |
| connective tissue development | GO:0061448 | 179 | 0.015 | |
| actin filament polymerization | GO:0030041 | 44 | 0.015 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.014 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.014 | |
| heart morphogenesis | GO:0003007 | 178 | 0.014 | |
| regulation of exocytosis | GO:0017157 | 61 | 0.014 | |
| vesicle transport along microtubule | GO:0047496 | 9 | 0.014 | |
| segmentation | GO:0035282 | 93 | 0.014 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.014 | |
| vesicle organization | GO:0016050 | 60 | 0.014 | |
| negative regulation of endopeptidase activity | GO:0010951 | 44 | 0.014 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.014 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.014 | |
| regulation of necrotic cell death | GO:0010939 | 13 | 0.014 | |
| striated muscle contraction | GO:0006941 | 45 | 0.014 | Mouse |
| myosin filament assembly | GO:0031034 | 2 | 0.014 | |
| muscle cell proliferation | GO:0033002 | 52 | 0.014 | |
| t cell activation | GO:0042110 | 289 | 0.014 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.014 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.014 | |
| methylation | GO:0032259 | 134 | 0.014 | |
