| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.404 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.364 | |
| mitochondrion organization | GO:0007005 | 134 | 0.351 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.330 | |
| atp metabolic process | GO:0046034 | 75 | 0.309 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.299 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.286 | |
| transmembrane transport | GO:0055085 | 412 | 0.286 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.276 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.256 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.246 | |
| positive regulation of peptidase activity | GO:0010952 | 49 | 0.239 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.236 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.233 | |
| cellular respiration | GO:0045333 | 38 | 0.201 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.198 | |
| mitochondrial transport | GO:0006839 | 36 | 0.166 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.164 | |
| response to oxidative stress | GO:0006979 | 123 | 0.160 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.152 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.149 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.137 | |
| regulation of phosphatidylcholine biosynthetic process | GO:2001245 | 2 | 0.132 | |
| defecation | GO:0030421 | 1 | 0.126 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.126 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.124 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.124 | Worm |
| protein processing | GO:0016485 | 163 | 0.121 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.116 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.114 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 34 | 0.113 | |
| protein catabolic process | GO:0030163 | 221 | 0.111 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.103 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.097 | |
| protein localization to mitochondrion | GO:0070585 | 15 | 0.097 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.094 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.089 | |
| cellular homeostasis | GO:0019725 | 240 | 0.087 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.082 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.082 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.079 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.078 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.076 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.076 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.073 | |
| protein maturation | GO:0051604 | 176 | 0.071 | |
| dna metabolic process | GO:0006259 | 303 | 0.070 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.069 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.066 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.064 | |
| spermatogenesis | GO:0007283 | 284 | 0.061 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.059 | |
| zymogen activation | GO:0031638 | 41 | 0.059 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.059 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.059 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.058 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.058 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.057 | |
| oxidation reduction process | GO:0055114 | 342 | 0.054 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.053 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.053 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.048 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.048 | |
| membrane organization | GO:0061024 | 245 | 0.047 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.047 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.047 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.046 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.046 | |
| locomotory behavior | GO:0007626 | 195 | 0.045 | |
| male gamete generation | GO:0048232 | 285 | 0.045 | |
| gland development | GO:0048732 | 330 | 0.044 | |
| response to superoxide | GO:0000303 | 16 | 0.043 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.042 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.042 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.042 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.042 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.040 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.040 | |
| multicellular organismal aging | GO:0010259 | 24 | 0.040 | |
| proteasomal ubiquitin independent protein catabolic process | GO:0010499 | 1 | 0.039 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.039 | |
| glycerolipid metabolic process | GO:0046486 | 122 | 0.039 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.038 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.038 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.038 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.036 | |
| protein localization to organelle | GO:0033365 | 185 | 0.035 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.035 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.034 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.034 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.033 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.033 | |
| amine metabolic process | GO:0009308 | 45 | 0.033 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.033 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.033 | |
| cation transport | GO:0006812 | 399 | 0.032 | |
| endocytosis | GO:0006897 | 168 | 0.032 | |
| protein import | GO:0017038 | 101 | 0.032 | |
| response to oxygen levels | GO:0070482 | 62 | 0.032 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.032 | |
| regulation of blood pressure | GO:0008217 | 93 | 0.030 | |
| positive regulation of growth | GO:0045927 | 104 | 0.030 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.030 | |
| gonad development | GO:0008406 | 141 | 0.029 | Worm |
| nitrogen compound transport | GO:0071705 | 271 | 0.029 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.029 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 36 | 0.028 | |
| regulation of mitochondrial membrane potential | GO:0051881 | 17 | 0.028 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.028 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.027 | |
| protein polymerization | GO:0051258 | 57 | 0.027 | |
| regulation of protein processing | GO:0070613 | 96 | 0.027 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.027 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.026 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.026 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.026 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.025 | |
| anion transport | GO:0006820 | 177 | 0.024 | |
| age dependent response to oxidative stress | GO:0001306 | 3 | 0.024 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.024 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.024 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.024 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.024 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 27 | 0.024 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.024 | |
| extracellular structure organization | GO:0043062 | 148 | 0.024 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.023 | |
| response to oxygen radical | GO:0000305 | 16 | 0.023 | |
| response to hypoxia | GO:0001666 | 58 | 0.023 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.023 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.023 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.022 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.022 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.022 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.022 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.021 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.021 | |
| negative regulation of growth | GO:0045926 | 99 | 0.021 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.021 | |
| regulation of cell activation | GO:0050865 | 289 | 0.021 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.021 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.021 | |
| neural tube formation | GO:0001841 | 108 | 0.020 | |
| regulation of cell motility | GO:2000145 | 236 | 0.020 | |
| intracellular protein transport | GO:0006886 | 204 | 0.020 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.020 | |
| regulation of defense response | GO:0031347 | 233 | 0.020 | |
| mitochondrion morphogenesis | GO:0070584 | 13 | 0.020 | |
| mapk cascade | GO:0000165 | 281 | 0.020 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.020 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.020 | |
| negative regulation of alcohol biosynthetic process | GO:1902931 | 4 | 0.020 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.020 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.019 | |
| cytokine production | GO:0001816 | 319 | 0.019 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.019 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.019 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.019 | |
| immune effector process | GO:0002252 | 321 | 0.018 | |
| regulation of membrane permeability | GO:0090559 | 18 | 0.018 | |
| sulfur compound biosynthetic process | GO:0044272 | 37 | 0.018 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.018 | |
| age dependent general metabolic decline | GO:0007571 | 3 | 0.018 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.018 | |
| phagocytosis | GO:0006909 | 66 | 0.018 | |
| regulation of phospholipid biosynthetic process | GO:0071071 | 3 | 0.018 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.018 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.018 | |
| oxidative phosphorylation | GO:0006119 | 14 | 0.017 | |
| t cell activation | GO:0042110 | 289 | 0.017 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.017 | |
| phosphatidylethanolamine metabolic process | GO:0046337 | 2 | 0.017 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.017 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.017 | |
| dephosphorylation | GO:0016311 | 129 | 0.017 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.017 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.017 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 27 | 0.016 | |
| negative regulation of mitochondrion organization | GO:0010823 | 9 | 0.016 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.016 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.016 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.016 | |
| response to inorganic substance | GO:0010035 | 96 | 0.016 | |
| cation homeostasis | GO:0055080 | 212 | 0.016 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.015 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.015 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.015 | |
| regulation of cell growth | GO:0001558 | 91 | 0.015 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.015 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.015 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.015 | |
| activation of immune response | GO:0002253 | 138 | 0.015 | |
| blastocyst development | GO:0001824 | 80 | 0.015 | |
| coenzyme biosynthetic process | GO:0009108 | 23 | 0.015 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.015 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.015 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.015 | |
| heart morphogenesis | GO:0003007 | 178 | 0.014 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.014 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.014 | |
| wound healing | GO:0042060 | 157 | 0.014 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.014 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.014 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.014 | |
| regulation of mitochondrion organization | GO:0010821 | 27 | 0.014 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.014 | |
| protein ubiquitination | GO:0016567 | 171 | 0.014 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.014 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.014 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.014 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.014 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.014 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.013 | |
| neuron death | GO:0070997 | 154 | 0.013 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.013 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.013 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.013 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.013 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.013 | |
| regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity | GO:2000311 | 11 | 0.013 | |
| protein targeting | GO:0006605 | 143 | 0.013 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.013 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.013 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.013 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.013 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.013 | |
| synaptic transmission | GO:0007268 | 329 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.013 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.012 | |
| multicellular organism growth | GO:0035264 | 161 | 0.012 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.012 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.012 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.012 | |
| insulin secretion | GO:0030073 | 89 | 0.012 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.012 | |
| protein methylation | GO:0006479 | 81 | 0.012 | |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.012 | |
| sensory perception | GO:0007600 | 245 | 0.012 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.012 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.012 | |
| purine nucleotide biosynthetic process | GO:0006164 | 65 | 0.012 | |
| engulfment of apoptotic cell | GO:0043652 | 3 | 0.012 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.012 | |
| inflammatory response | GO:0006954 | 244 | 0.012 | |
| monocarboxylic acid biosynthetic process | GO:0072330 | 61 | 0.012 | |
| phosphatidylglycerol metabolic process | GO:0046471 | 3 | 0.012 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.012 | |
| immune response activating signal transduction | GO:0002757 | 116 | 0.012 | |
| innate immune response | GO:0045087 | 157 | 0.012 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.012 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.011 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.011 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.011 | |
| germ cell development | GO:0007281 | 185 | 0.011 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.011 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.011 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.011 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.011 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.011 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.011 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.011 | |
| oogenesis | GO:0048477 | 56 | 0.011 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.011 | |
| tube formation | GO:0035148 | 140 | 0.010 | |
| negative regulation of phospholipid biosynthetic process | GO:0071072 | 1 | 0.010 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.010 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.010 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.010 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.010 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.010 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.010 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.010 | |
| hydrogen peroxide metabolic process | GO:0042743 | 16 | 0.010 | |
| leukocyte migration | GO:0050900 | 124 | 0.010 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.010 | |