Mus musculus

182 known processes

Nkx2-2

NK2 transcription factor related, locus 2 (Drosophila)

(Aliases: Nkx-2.2,tinman,Nkx2.2)

Nkx2-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonogenesisGO:00074092740.976
Zebrafish Mouse
spinal cord developmentGO:0021510810.975
central nervous system neuron differentiationGO:00219531620.956
glial cell differentiationGO:00100011310.950
spinal cord motor neuron cell fate specificationGO:0021520130.934
cell fate commitmentGO:00451652100.931
neuron fate specificationGO:0048665300.916
action potentialGO:0001508780.910
oligodendrocyte developmentGO:0014003200.903
cell differentiation in spinal cordGO:0021515530.895
smoothened signaling pathwayGO:00072241050.885
gliogenesisGO:00420631410.876
central nervous system neuron developmentGO:0021954670.872
neuron migrationGO:00017641220.866
Mouse
oligodendrocyte differentiationGO:0048709530.856
glial cell developmentGO:0021782540.854
ensheathment of neuronsGO:0007272760.852
myelinationGO:0042552740.831
forebrain developmentGO:00309003020.819
Mouse
transmission of nerve impulseGO:0019226760.817
type b pancreatic cell differentiationGO:0003309130.806
regionalizationGO:00030023370.802
connective tissue developmentGO:00614481790.780
Mouse
skeletal system developmentGO:00015013560.778
Mouse
diencephalon developmentGO:0021536630.775
Mouse
pituitary gland developmentGO:0021983380.773
Mouse
ventral spinal cord developmentGO:0021517480.771
negative regulation of cell developmentGO:00107211690.759
camera type eye developmentGO:00430102660.756
spinal cord motor neuron differentiationGO:0021522350.745
forebrain generation of neuronsGO:0021872630.738
Mouse
axon ensheathmentGO:0008366760.737
endocrine system developmentGO:0035270980.728
cell fate determinationGO:0001709320.722
neuronal action potentialGO:0019228540.695
motor neuron migrationGO:009747540.680
cerebral cortex developmentGO:0021987860.677
Mouse
ventral spinal cord interneuron fate commitmentGO:0060579140.676
regulation of gliogenesisGO:0014013500.674
stem cell developmentGO:00488642190.660
transdifferentiationGO:006029010.652
ventral spinal cord interneuron specificationGO:0021521110.647
neuroepithelial cell differentiationGO:0060563370.627
enteroendocrine cell differentiationGO:0035883160.627
regulation of neural precursor cell proliferationGO:2000177700.625
cell fate specificationGO:0001708720.612
extracellular matrix organizationGO:00301981470.604
negative regulation of neuron differentiationGO:00456651010.598
columnar cuboidal epithelial cell differentiationGO:0002065820.581
negative regulation of glial cell differentiationGO:0045686210.577
kidney epithelium developmentGO:00720731210.560
neural precursor cell proliferationGO:00613511210.559
spinal cord patterningGO:0021511250.557
cellular amino acid metabolic processGO:00065201030.553
multicellular organismal signalingGO:0035637910.548
epidermis developmentGO:00085441870.533
regulation of secretion by cellGO:19035302490.532
pancreatic pp cell differentiationGO:000331220.511
cell fate specification involved in pattern specificationGO:0060573110.497
cardiac chamber morphogenesisGO:0003206930.492
Mouse
positive regulation of secretion by cellGO:19035321140.488
chondrocyte differentiationGO:0002062720.485
Mouse
axon guidanceGO:00074111410.468
Zebrafish Mouse
positive regulation of peptide secretionGO:0002793330.465
negative regulation of nervous system developmentGO:00519611560.452
pancreas developmentGO:0031016570.449
regulation of neuron differentiationGO:00456642810.445
ureteric bud developmentGO:0001657940.441
mesonephric tubule developmentGO:0072164940.434
hippocampus developmentGO:0021766520.434
Mouse
limb morphogenesisGO:00351081490.426
epithelial cell developmentGO:00020641590.426
auditory receptor cell fate determinationGO:004266830.425
hindbrain developmentGO:00309021280.425
peripheral nervous system neuron axonogenesisGO:004893630.424
endocrine pancreas developmentGO:0031018290.415
positive regulation of peptide hormone secretionGO:0090277310.414
chemotaxisGO:00069352470.414
Zebrafish Mouse
nitrogen compound transportGO:00717052710.413
regulation of neuroblast proliferationGO:1902692270.408
central nervous system projection neuron axonogenesisGO:0021952210.404
developmental growth involved in morphogenesisGO:00605601380.393
positive regulation of neuroblast proliferationGO:0002052190.387
mesenchymal cell differentiationGO:00487621070.385
regulation of neuron apoptotic processGO:00435231220.381
regulation of ossificationGO:00302781120.373
regulation of membrane potentialGO:00423911920.369
determination of left right symmetryGO:0007368800.368
Mouse
central nervous system neuron axonogenesisGO:0021955280.366
glandular epithelial cell differentiationGO:0002067380.360
neuron projection extensionGO:1990138640.350
positive regulation of insulin secretionGO:0032024260.350
cell type specific apoptotic processGO:00972852680.348
Mouse
regulation of peptide secretionGO:0002791770.345
inner ear morphogenesisGO:00424721010.344
positive regulation of secretionGO:00510471300.344
limbic system developmentGO:0021761720.341
Mouse
negative regulation of cell proliferationGO:00082852960.340
Mouse
cerebellum developmentGO:0021549770.340
organic hydroxy compound metabolic processGO:19016152030.339
spinal cord motor neuron migrationGO:009747640.333
sensory organ morphogenesisGO:00905962420.327
Mouse
multi organism behaviorGO:0051705620.326
limb developmentGO:00601731660.323
positive regulation of cell developmentGO:00107202370.323
regulation of stem cell proliferationGO:0072091780.322
telencephalon developmentGO:00215371860.320
Mouse
negative regulation of gliogenesisGO:0014014230.313
regulation of axon diameterGO:003113360.304
embryonic epithelial tube formationGO:00018381300.300
regulation of glial cell differentiationGO:0045685410.299
cell adhesionGO:00071553290.299
astrocyte differentiationGO:0048708430.297
forebrain neuron developmentGO:0021884300.295
cell proliferation in hindbrainGO:0021534100.288
central nervous system myelinationGO:0022010120.286
cerebral cortex neuron differentiationGO:0021895190.280
Mouse
ventral spinal cord interneuron differentiationGO:0021514160.276
columnar cuboidal epithelial cell developmentGO:0002066290.273
amide transportGO:00428861380.273
spermatogenesisGO:00072832840.269
regulation of secretionGO:00510462740.269
somitogenesisGO:0001756690.269
monosaccharide metabolic processGO:00059961060.268
cerebral cortex gabaergic interneuron migrationGO:002185360.268
positive regulation of auditory receptor cell differentiationGO:004560910.265
neuroendocrine cell differentiationGO:006110170.263
cellular response to monosaccharide stimulusGO:0071326470.262
ureteric bud morphogenesisGO:0060675620.259
insulin secretionGO:0030073890.258
digestive tract morphogenesisGO:00485461470.254
Mouse
forebrain neuron differentiationGO:0021879520.253
Mouse
regulation of peptide transportGO:0090087910.245
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specificationGO:002191340.238
regulation of neuron deathGO:19012141340.237
cellular response to glucose stimulusGO:0071333450.236
male gamete generationGO:00482322850.235
regulation of hormone levelsGO:00108172110.235
formation of primary germ layerGO:0001704770.231
positive regulation of neural precursor cell proliferationGO:2000179420.228
tongue developmentGO:0043586180.225
Mouse
digestive tract developmentGO:00485651900.225
developmental cell growthGO:0048588840.225
mesenchymal cell developmentGO:0014031930.224
nephron tubule developmentGO:0072080840.222
positive regulation of nervous system developmentGO:00519622210.221
peptide transportGO:00158331330.219
positive regulation of gliogenesisGO:0014015270.219
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.218
neuroblast proliferationGO:0007405490.217
blood circulationGO:00080151950.217
Mouse
cell proliferation in forebrainGO:0021846300.216
cell differentiation involved in kidney developmentGO:0061005330.215
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.215
paraxial mesodermal cell fate commitmentGO:004834320.211
neuron projection guidanceGO:00974851410.211
Zebrafish Mouse
pancreatic a cell differentiationGO:000331070.208
regulation of hormone secretionGO:0046883880.208
astrocyte fate commitmentGO:006001840.205
developmental maturationGO:00217001930.205
protein localization to nucleusGO:00345041210.205
muscle cell differentiationGO:00426922610.204
Mouse
positive regulation of neuron differentiationGO:00456661410.201
pallium developmentGO:00215431200.201
Mouse
catecholamine biosynthetic processGO:0042423110.199
heart morphogenesisGO:00030071780.199
Mouse
regulation of smoothened signaling pathwayGO:0008589580.199
spinal cord oligodendrocyte cell fate specificationGO:002153030.197
peptide secretionGO:00027901140.197
regulation of cell cycleGO:00517262810.193
embryonic placenta developmentGO:0001892980.193
embryonic limb morphogenesisGO:00303261260.192
stem cell proliferationGO:00720891170.191
bone mineralizationGO:0030282540.190
neuromuscular process controlling balanceGO:0050885590.189
mesenchyme developmentGO:00604851520.188
Mouse
regulation of neuron migrationGO:2001222220.187
stem cell differentiationGO:00488632680.186
Mouse
morphogenesis of embryonic epitheliumGO:00163311590.184
organonitrogen compound biosynthetic processGO:19015661920.183
negative regulation of type b pancreatic cell apoptotic processGO:200067530.180
lateral motor column neuron migrationGO:009747730.179
regulation of epithelial cell proliferationGO:00506781410.179
Mouse
neural crest cell differentiationGO:0014033540.178
regulation of cartilage developmentGO:0061035440.178
Mouse
somatotropin secreting cell differentiationGO:006012640.177
positive regulation of cellular amino acid metabolic processGO:004576430.177
positive regulation of stem cell proliferationGO:2000648590.176
regulation of organ morphogenesisGO:20000271440.176
regulation of cell migrationGO:00303342190.175
urogenital system developmentGO:00016552610.175
leukocyte differentiationGO:00025213420.174
Mouse
cell maturationGO:00484691270.174
neuron apoptotic processGO:00514021420.172
neuroblast differentiationGO:001401620.172
peptide hormone secretionGO:00300721090.170
regulation of bone mineralizationGO:0030500310.169
cardiac ventricle developmentGO:0003231830.169
Mouse
ear developmentGO:00435832000.168
Mouse
regulation of auditory receptor cell differentiationGO:004560740.166
regulation of cell motilityGO:20001452360.166
mitral valve developmentGO:000317440.165
glucose homeostasisGO:00425931280.162
carbohydrate homeostasisGO:00335001280.161
positive regulation of cellular amine metabolic processGO:003324050.160
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.160
regulation of neuron projection developmentGO:00109751690.160
cerebellum morphogenesisGO:0021587420.158
mitotic cell cycleGO:00002781950.158
skin developmentGO:00435882200.158
cell differentiation involved in embryonic placenta developmentGO:0060706260.157
cochlea morphogenesisGO:0090103220.157
response to organonitrogen compoundGO:00102432460.157
embryonic appendage morphogenesisGO:00351131260.156
appendage developmentGO:00487361660.156
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.154
fat cell differentiationGO:00454441600.153
hormone secretionGO:00468791280.153
cerebral cortex gabaergic interneuron differentiationGO:002189290.152
Mouse
digestive system developmentGO:00551232000.147
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.147
regulation of peptide hormone secretionGO:0090276750.145
regulation of transcription involved in cell fate commitmentGO:0060850150.144
retina morphogenesis in camera type eyeGO:0060042450.142
substrate independent telencephalic tangential migrationGO:002182680.142
renal system developmentGO:00720012250.142
metanephros developmentGO:0001656790.142
response to alkaloidGO:0043279340.142
paraxial mesodermal cell differentiationGO:004834220.142
cell proliferation in external granule layerGO:0021924100.141
myeloid cell differentiationGO:00300992330.141
Mouse
positive regulation of inner ear receptor cell differentiationGO:200098210.140
cerebral cortex gabaergic interneuron developmentGO:002189460.140
neural crest cell developmentGO:0014032480.140
synaptic transmission gabaergicGO:0051932190.139
regulation of response to woundingGO:19030341890.139
inorganic ion transmembrane transportGO:00986602340.136
Mouse
cellular carbohydrate metabolic processGO:00442621190.134
cell growthGO:00160491300.133
nephron morphogenesisGO:0072028690.133
dopaminergic neuron differentiationGO:0071542140.133
response to drugGO:0042493750.130
auditory receptor cell fate specificationGO:004266710.128
regulation of body fluid levelsGO:00508781620.128
sensory perception of mechanical stimulusGO:00509541070.126
molting cycleGO:0042303900.126
respiratory system developmentGO:00605411900.126
Mouse
kidney morphogenesisGO:0060993830.125
myotube differentiationGO:00149021050.125
ameboidal type cell migrationGO:00016671280.125
neuromuscular processGO:0050905990.124
regulation of cellular component sizeGO:00325351210.124
cerebellar granule cell precursor proliferationGO:0021930100.123
tendon cell differentiationGO:003599040.123
lung epithelial cell differentiationGO:0060487290.123
Mouse
stem cell maintenanceGO:00198271300.122
embryonic skeletal system developmentGO:00487061200.122
Mouse
somatotropin secreting cell developmentGO:006013320.121
metanephric loop of henle developmentGO:007223640.121
histone modificationGO:00165701590.120
small gtpase mediated signal transductionGO:0007264970.119
regulation of cellular amine metabolic processGO:0033238200.119
kidney developmentGO:00018222130.119
mesonephros developmentGO:0001823970.118
hair follicle developmentGO:0001942850.118
hexose metabolic processGO:0019318980.118
sensory perceptionGO:00076002450.118
regulation of system processGO:00440572000.117
Mouse
bmp signaling pathwayGO:0030509930.117
Mouse
peptidyl amino acid modificationGO:00181933360.116
cellular response to peptideGO:1901653920.116
forebrain regionalizationGO:0021871250.114
Mouse
regulation of osteoblast differentiationGO:0045667670.114
myelination in peripheral nervous systemGO:0022011190.113
positive regulation of cell migrationGO:00303351090.113
protein import into nucleusGO:0006606950.112
lymphocyte differentiationGO:00300982420.111
Mouse
regulation of cellular carbohydrate metabolic processGO:0010675750.111
cell fate commitment involved in pattern specificationGO:0060581140.110
gabaergic neuron differentiationGO:0097154110.109
Mouse
odontogenesis of dentin containing toothGO:0042475660.108
Mouse
catecholamine metabolic processGO:0006584300.106
myoblast differentiationGO:0045445520.106
epithelial cell proliferationGO:00506731740.106
Mouse
type b pancreatic cell developmentGO:0003323100.106
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.105
leukocyte homeostasisGO:0001776790.105
Mouse
negative regulation of molecular functionGO:00440922580.105
regulation of axon extensionGO:0030516430.104
cell differentiation in hindbrainGO:0021533240.103
extracellular structure organizationGO:00430621480.103
phenol containing compound metabolic processGO:0018958600.102
regulation of anatomical structure sizeGO:00900661780.102
apoptotic signaling pathwayGO:00971903060.102
embryonic organ morphogenesisGO:00485622760.101
Mouse
neural tube developmentGO:00219151600.100
Zebrafish
autonomic nervous system developmentGO:0048483430.099
stem cell fate specificationGO:004886630.099
positive regulation of protein modification processGO:00314012990.097
developmental programmed cell deathGO:0010623410.097
Mouse
development of primary sexual characteristicsGO:00451371430.096
Mouse
metanephric dct cell differentiationGO:007224030.096
thyroid stimulating hormone secreting cell differentiationGO:006012940.095
septum primum developmentGO:000328440.095
cerebral cortex radial glia guided migrationGO:0021801170.094
renal tubule developmentGO:0061326870.094
positive regulation of protein phosphorylationGO:00019342420.094
regulation of bmp signaling pathwayGO:0030510600.094
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.094
ossificationGO:00015032160.093
corpus callosum morphogenesisGO:002154030.093
metanephric nephron tubule developmentGO:0072234160.093
ventral midline developmentGO:000741840.092
Zebrafish
positive regulation of mechanoreceptor differentiationGO:004563310.091
biomineral tissue developmentGO:0031214640.090
embryonic heart tube developmentGO:0035050650.090
Mouse
regulation of insulin secretion involved in cellular response to glucose stimulusGO:0061178310.089
glucose metabolic processGO:0006006920.088
ras protein signal transductionGO:0007265770.088
regulation of chondrocyte differentiationGO:0032330330.088
Mouse
anion transportGO:00068201770.088
interneuron migration from the subpallium to the cortexGO:002183070.087
cartilage developmentGO:00512161400.086
Mouse
cochlea developmentGO:0090102350.086
cellular response to cytokine stimulusGO:00713451890.086
nephron tubule morphogenesisGO:0072078680.085
regulation of muscle contractionGO:0006937490.085
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.084
satellite cell activation involved in skeletal muscle regenerationGO:001490130.084
pyramidal neuron migrationGO:002185210.084
regulation of blood circulationGO:1903522930.083
Mouse
chromatin modificationGO:00165681870.083
inner ear receptor cell differentiationGO:0060113610.083
negative regulation of phosphate metabolic processGO:00459361840.083
spinal cord oligodendrocyte cell differentiationGO:002152930.082
skeletal muscle organ developmentGO:00605381630.081
noradrenergic neuron differentiationGO:000335760.081
neural retina developmentGO:0003407410.080
hemangioblast cell differentiationGO:006021710.080
cellular response to growth factor stimulusGO:00713631970.079
subpallium developmentGO:0021544200.079
regulation of sequence specific dna binding transcription factor activityGO:00510901060.079
horizontal cell localizationGO:003585210.078
multicellular organismal reproductive behaviorGO:0033057230.078
male sex determinationGO:0030238140.078
skeletal system morphogenesisGO:00487052030.078
Mouse
cardiocyte differentiationGO:0035051870.078
Mouse
visceral motor neuron differentiationGO:002152430.078
amine metabolic processGO:0009308450.077
carbohydrate metabolic processGO:00059752300.077
forebrain neuron fate commitmentGO:0021877130.077
Mouse
positive regulation of glial cell differentiationGO:0045687210.077
determination of heart left right asymmetryGO:0061371480.076
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.076
astrocyte developmentGO:0014002120.075
photoreceptor cell differentiationGO:0046530520.074
positive regulation of skeletal muscle tissue regenerationGO:004341540.074
cation transportGO:00068123990.074
Mouse
lung morphogenesisGO:0060425500.073
skeletal muscle cell differentiationGO:0035914660.073
cellular response to organonitrogen compoundGO:00714171450.073
cardiac septum morphogenesisGO:0060411460.073
g protein coupled receptor signaling pathwayGO:00071862430.073
gland developmentGO:00487323300.072
Mouse
ectoderm formationGO:000170530.072
gonad developmentGO:00084061410.072
Mouse
metencephalon developmentGO:0022037890.072
mesodermal cell differentiationGO:0048333220.071
hair cell differentiationGO:0035315400.071
chondrocyte developmentGO:0002063240.071
neuron deathGO:00709971540.071
bone developmentGO:00603481200.071
olfactory bulb developmentGO:0021772300.070
retina development in camera type eyeGO:00600411190.070
nephron epithelium developmentGO:0072009920.069
nuclear transportGO:00511691390.069
corpus callosum developmentGO:0022038100.069
muscle contractionGO:00069361010.069
Mouse
epithelial tube formationGO:00721751300.069
eye photoreceptor cell differentiationGO:0001754410.069
dentate gyrus developmentGO:0021542140.068
neuroblast fate commitmentGO:001401710.067
positive regulation of osteoblast differentiationGO:0045669340.067
cellular amine metabolic processGO:0044106440.067
regulation of synaptic plasticityGO:0048167870.067
regulation of cell activationGO:00508652890.066
peptidyl tyrosine modificationGO:00182121450.066
epithelial to mesenchymal transitionGO:0001837470.066
regulation of glucose metabolic processGO:0010906600.066
membrane depolarizationGO:0051899640.066
muscle tissue developmentGO:00605373080.066
Mouse
negative regulation of cell cycleGO:00457861230.065
syncytium formation by plasma membrane fusionGO:0000768420.064
protein maturationGO:00516041760.064
regulation of cyclic nucleotide metabolic processGO:0030799400.064
neuron maturationGO:0042551290.064
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.064
regulation of protein transportGO:00512231630.063
germ line sex determinationGO:001899230.063
regulation of angiogenesisGO:0045765810.063
prostate gland developmentGO:0030850480.063
circulatory system processGO:00030131970.062
Mouse
regulation of biomineral tissue developmentGO:0070167330.062
positive regulation of keratinocyte proliferationGO:001083840.061
regenerationGO:0031099380.061
anterior commissure morphogenesisGO:002196060.061
renal vesicle inductionGO:007203430.060
semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:007152710.060
mechanoreceptor differentiationGO:0042490670.060
determination of left right asymmetry in nervous systemGO:003554510.059
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.059
negative regulation of glial cell proliferationGO:006025340.059
sensory perception of light stimulusGO:0050953540.059
regulation of transcription from rna polymerase ii promoter involved in spinal cord motor neuron fate specificationGO:002191230.059
lymphocyte apoptotic processGO:0070227540.059
cellular ketone metabolic processGO:0042180840.059
positive regulation of bmp signaling pathwayGO:0030513230.059
carbohydrate transportGO:0008643620.058
t cell activationGO:00421102890.058
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.058
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.057
ion transmembrane transportGO:00342203610.057
Mouse
embryonic skeletal system morphogenesisGO:0048704910.057
mesonephric epithelium developmentGO:0072163940.057
paramesonephric duct developmentGO:006120530.056
auditory receptor cell differentiationGO:0042491370.056
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.056
neural tube formationGO:00018411080.055
retinal bipolar neuron differentiationGO:006004050.055
positive regulation of hormone secretionGO:0046887380.055
regulation of satellite cell activation involved in skeletal muscle regenerationGO:001471730.055
sensory perception of soundGO:0007605970.055
protein catabolic processGO:00301632210.055
regulation of transmembrane transportGO:00347621280.055
Mouse
pharyngeal system developmentGO:0060037170.055
Mouse
tube formationGO:00351481400.055
regulation of cellular ketone metabolic processGO:0010565660.055
matingGO:0007618270.055
tube closureGO:0060606910.054
mitotic cell cycle processGO:19030471590.054
response to painGO:0048265260.054
stem cell fate commitmentGO:004886550.054
tendon formationGO:003599240.054
gonad morphogenesisGO:003526210.054
learning or memoryGO:00076111480.054
midbrain hindbrain boundary morphogenesisGO:002155540.054
renal vesicle morphogenesisGO:0072077150.053
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.053
associative learningGO:0008306610.053
endocardium formationGO:006021440.053
apoptotic process involved in morphogenesisGO:0060561250.053
Mouse
regulation of stem cell differentiationGO:2000736500.052
Mouse
nitric oxide mediated signal transductionGO:000726340.052
spinal cord dorsal ventral patterningGO:0021513230.052
somatic stem cell maintenanceGO:0035019470.052
sympathetic nervous system developmentGO:0048485220.052
inorganic anion transportGO:0015698430.052
establishment or maintenance of cell polarityGO:0007163860.052
positive regulation of epithelial cell proliferationGO:0050679680.052
midgut developmentGO:000749440.051
transmembrane transportGO:00550854120.051
Mouse
lung developmentGO:00303241640.051
Mouse
cellular response to external stimulusGO:0071496880.051
regulation of protein localizationGO:00328802310.051
metanephric nephron tubule formationGO:007228940.050
respiratory tube developmentGO:00303231670.050
Mouse
negative regulation of neuron deathGO:1901215980.049
pancreatic a cell fate commitmentGO:000332620.049
adult locomotory behaviorGO:0008344910.049
carbohydrate derivative biosynthetic processGO:19011371830.049
embryonic digestive tract developmentGO:0048566270.049
positive regulation of epithelial cell migrationGO:0010634190.049
multicellular organism growthGO:00352641610.049
positive regulation of epithelial cell differentiation involved in kidney developmentGO:200069820.048
noradrenergic neuron developmentGO:000335830.048
gall bladder developmentGO:006101020.048
ear morphogenesisGO:00424711180.048
Mouse
mesonephric duct formationGO:007218120.047
wound healingGO:00420601570.047
female sex determinationGO:003023710.047
regulation of cerebellar granule cell precursor proliferationGO:0021936120.047
neural fold elevation formationGO:002150210.047
regulation of purine nucleotide biosynthetic processGO:1900371340.047
mesoderm developmentGO:00074981000.047
fear responseGO:0042596330.047
positive regulation of cell motilityGO:20001471160.047
neural crest cell migrationGO:0001755320.046
bone morphogenesisGO:0060349780.046
regulation of neurotransmitter levelsGO:0001505870.046
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.046
regulation of kinase activityGO:00435492490.046

Nkx2-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
diabetes mellitusDOID:935100.083
disease of metabolismDOID:001466700.083
carbohydrate metabolism diseaseDOID:005001300.083
glucose metabolism diseaseDOID:419400.083
acquired metabolic diseaseDOID:006015800.083
disease of anatomical entityDOID:700.066
musculoskeletal system diseaseDOID:1700.066
connective tissue diseaseDOID:6500.066