Mus musculus

217 known processes

Nkx2-1

NK2 homeobox 1

(Aliases: Titf1,Nkx2.1,AV026640,Ttf-1,T/EBP)

Nkx2-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic skeletal system developmentGO:00487061200.992
Mouse
paraxial mesodermal cell differentiationGO:004834220.987
paraxial mesodermal cell fate commitmentGO:004834320.979
lung developmentGO:00303241640.977
respiratory system developmentGO:00605411900.975
ureteric bud morphogenesisGO:0060675620.971
respiratory tube developmentGO:00303231670.970
lung morphogenesisGO:0060425500.970
Human
epithelial tube morphogenesisGO:00605623030.966
Human Mouse
bmp signaling pathwayGO:0030509930.965
Mouse
nephron epithelium morphogenesisGO:0072088680.956
pallium developmentGO:00215431200.954
embryonic organ morphogenesisGO:00485622760.952
Mouse
glandular epithelial cell differentiationGO:0002067380.950
Mouse
kidney developmentGO:00018222130.950
endocrine system developmentGO:0035270980.949
telencephalon developmentGO:00215371860.949
nephron tubule morphogenesisGO:0072078680.949
carbon catabolite activation of transcriptionGO:004599140.948
central nervous system neuron differentiationGO:00219531620.947
lung cell differentiationGO:0060479300.947
regionalizationGO:00030023370.944
embryonic skeletal system morphogenesisGO:0048704910.936
forebrain cell migrationGO:0021885580.930
palate developmentGO:0060021760.924
mesenchyme developmentGO:00604851520.915
Human Mouse
columnar cuboidal epithelial cell differentiationGO:0002065820.914
Mouse
cerebral cortex cell migrationGO:0021795440.914
morphogenesis of a branching epitheliumGO:00611381930.910
Human
urogenital system developmentGO:00016552610.909
regulation of organ morphogenesisGO:20000271440.907
neural tube patterningGO:0021532430.903
appendage morphogenesisGO:00351071490.901
lacrimal gland developmentGO:003280850.896
cardiac muscle cell proliferationGO:0060038310.883
Mouse
renal tubule developmentGO:0061326870.870
ureteric bud developmentGO:0001657940.865
lung epithelial cell differentiationGO:0060487290.861
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.853
hair follicle morphogenesisGO:0031069290.852
gonad developmentGO:00084061410.850
neuron fate specificationGO:0048665300.848
Mouse
regulation of stem cell proliferationGO:0072091780.847
pituitary gland developmentGO:0021983380.846
lung epithelium developmentGO:0060428370.845
branching morphogenesis of an epithelial tubeGO:00487541590.844
Human
regulation of transcription from rna polymerase iii promoterGO:000635920.836
renal tubule morphogenesisGO:0061333720.830
regulation of neuron differentiationGO:00456642810.828
Mouse
paraxial mesoderm morphogenesisGO:0048340100.821
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.818
positive regulation of bmp signaling pathwayGO:0030513230.796
stem cell developmentGO:00488642190.796
Human
appendage developmentGO:00487361660.790
forebrain neuron differentiationGO:0021879520.787
cell fate commitmentGO:00451652100.785
positive regulation of stem cell proliferationGO:2000648590.782
neural tube developmentGO:00219151600.780
cerebral cortex radially oriented cell migrationGO:0021799310.780
embryonic viscerocranium morphogenesisGO:004870380.779
ear morphogenesisGO:00424711180.778
Mouse
regulation of organ growthGO:0046620610.776
Mouse
nephron developmentGO:00720061090.776
blood vessel remodelingGO:0001974330.767
positive regulation of neuron differentiationGO:00456661410.762
Mouse
pancreas developmentGO:0031016570.757
Mouse
neuron projection guidanceGO:00974851410.755
mesonephric tubule developmentGO:0072164940.753
positive regulation of transcription by glucoseGO:004601630.751
negative regulation of cell fate specificationGO:000999640.739
regulation of neural precursor cell proliferationGO:2000177700.737
regulation of cell cycleGO:00517262810.735
nephron tubule developmentGO:0072080840.733
carbon catabolite regulation of transcriptionGO:004599040.730
digestive tract morphogenesisGO:00485461470.730
Mouse
epithelial tube branching involved in lung morphogenesisGO:0060441280.727
Human
dorsal ventral neural tube patterningGO:0021904280.725
formation of primary germ layerGO:0001704770.723
striated muscle tissue developmentGO:00147062930.720
Mouse
pharynx developmentGO:006046510.718
angiogenesisGO:00015252010.718
cardiac chamber morphogenesisGO:0003206930.716
Mouse
regulation of cell migration involved in sprouting angiogenesisGO:009004940.714
pyramidal neuron migrationGO:002185210.707
locomotory behaviorGO:00076261950.706
placenta developmentGO:00018901400.704
regulation of cardiac muscle tissue growthGO:0055021260.702
Mouse
mesonephric tubule morphogenesisGO:0072171630.700
prostate gland morphogenesisGO:0060512320.699
segmentationGO:0035282930.698
nephron epithelium developmentGO:0072009920.695
positive regulation of smoothened signaling pathwayGO:0045880230.694
regulation of sequence specific dna binding transcription factor activityGO:00510901060.694
Mouse
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.691
cellular amino acid metabolic processGO:00065201030.690
female sex differentiationGO:0046660840.685
Rat
cell fate commitment involved in formation of primary germ layerGO:0060795260.685
neural precursor cell proliferationGO:00613511210.682
skeletal system morphogenesisGO:00487052030.679
Mouse
epithelial mesenchymal signaling involved in prostate gland developmentGO:006073820.675
thyroid stimulating hormone secreting cell differentiationGO:006012940.675
regulation of epithelial cell proliferationGO:00506781410.673
Mouse
positive regulation of growthGO:00459271040.670
forebrain developmentGO:00309003020.669
gland developmentGO:00487323300.669
branching involved in ureteric bud morphogenesisGO:0001658560.667
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.666
central nervous system neuron developmentGO:0021954670.661
positive regulation of neural precursor cell proliferationGO:2000179420.657
morphogenesis of a branching structureGO:00017632030.653
Human
glomerulus developmentGO:0032835400.652
nephron morphogenesisGO:0072028690.650
granulosa cell differentiationGO:006001410.646
organ growthGO:00352651170.642
Mouse
mesonephric epithelium developmentGO:0072163940.629
stem cell differentiationGO:00488632680.628
Human Mouse
digestive system developmentGO:00551232000.623
Mouse
mesoderm developmentGO:00074981000.622
limb developmentGO:00601731660.621
epithelial cell proliferationGO:00506731740.620
Mouse
thymus developmentGO:0048538410.620
stem cell proliferationGO:00720891170.620
regulation of bmp signaling pathwayGO:0030510600.618
lung alveolus developmentGO:0048286450.617
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.613
glomerular mesangial cell differentiationGO:007200830.611
semicircular canal fusionGO:006087910.609
mesenchyme morphogenesisGO:0072132320.604
gastrulationGO:00073691160.603
regulation of stem cell differentiationGO:2000736500.603
Human Mouse
positive regulation of cell developmentGO:00107202370.602
Mouse
mesangial cell differentiationGO:007200740.602
chemotaxisGO:00069352470.600
kidney vasculature developmentGO:0061440150.581
kidney morphogenesisGO:0060993830.578
cardiac muscle tissue growthGO:0055017370.573
Mouse
neuron migrationGO:00017641220.572
skeletal system developmentGO:00015013560.571
Mouse
chromatin modificationGO:00165681870.570
muscle tissue developmentGO:00605373080.565
Mouse
lens morphogenesis in camera type eyeGO:0002089240.565
neuroendocrine cell differentiationGO:006110170.564
bronchiole developmentGO:006043530.563
ovarian follicle developmentGO:0001541400.561
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.558
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.553
forebrain generation of neuronsGO:0021872630.538
ameboidal type cell migrationGO:00016671280.538
vascular endothelial growth factor receptor signaling pathwayGO:0048010240.535
extracellular matrix organizationGO:00301981470.534
positive regulation of epithelial cell proliferationGO:0050679680.531
regulation of vascular wound healingGO:006104320.531
axon guidanceGO:00074111410.529
mesonephros developmentGO:0001823970.524
mesodermal cell differentiationGO:0048333220.523
lung pattern specification processGO:006043210.522
regulation of mesenchymal cell proliferationGO:0010464370.522
molting cycleGO:0042303900.518
positive regulation of transcription from rna polymerase iii promoterGO:004594510.512
notch signaling pathwayGO:0007219710.512
cerebral cortex radial glia guided migrationGO:0021801170.510
mammary gland bud morphogenesisGO:006064840.509
mesoderm morphogenesisGO:0048332640.509
epidermis developmentGO:00085441870.508
carbohydrate metabolic processGO:00059752300.507
circulatory system processGO:00030131970.507
Mouse Rat
cardiac ventricle morphogenesisGO:0003208500.504
Mouse
sensory organ morphogenesisGO:00905962420.503
Mouse
kidney epithelium developmentGO:00720731210.502
epithelial cell developmentGO:00020641590.497
Mouse
regulation of voltage gated calcium channel activityGO:190138540.495
Mouse
prostate gland epithelium morphogenesisGO:0060740310.495
metanephros developmentGO:0001656790.493
regulation of high voltage gated calcium channel activityGO:190184120.492
epithelial cell maturation involved in prostate gland developmentGO:006074340.491
embryonic digit morphogenesisGO:0042733560.486
detection of glucoseGO:005159410.482
somatic sex determinationGO:001899320.479
glomerulus vasculature developmentGO:0072012140.477
regulation of apoptotic process involved in outflow tract morphogenesisGO:190225620.477
positive regulation of cell cycleGO:0045787920.475
epithelial tube formationGO:00721751300.474
regulation of peptide hormone secretionGO:0090276750.470
cellular ketone metabolic processGO:0042180840.462
negative regulation of apoptotic process involved in outflow tract morphogenesisGO:190225720.459
prostate gland stromal morphogenesisGO:006074120.458
glomerular mesangial cell developmentGO:007214430.457
morphogenesis of embryonic epitheliumGO:00163311590.457
mesenchymal cell differentiationGO:00487621070.456
Human
chondrocyte differentiationGO:0002062720.455
Mouse
hair cycleGO:0042633900.455
establishment of neuroblast polarityGO:004520010.453
developmental maturationGO:00217001930.452
prostate gland developmentGO:0030850480.448
inner ear morphogenesisGO:00424721010.447
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.443
Human
renal system vasculature developmentGO:0061437150.442
regulation of positive chemotaxisGO:005092670.438
regulation of heart growthGO:0060420310.438
Mouse
cell differentiation involved in kidney developmentGO:0061005330.437
submandibular salivary gland formationGO:006066110.434
mesoderm formationGO:0001707620.434
transcription from rna polymerase iii promoterGO:000638330.433
lung proximal distal axis specificationGO:006111510.433
cardiocyte differentiationGO:0035051870.431
Mouse
positive regulation of nervous system developmentGO:00519622210.430
Mouse
positive regulation of fat cell proliferationGO:007034610.429
prostate glandular acinus developmentGO:0060525120.427
regulation of smoothened signaling pathwayGO:0008589580.425
artery developmentGO:0060840530.421
hair follicle developmentGO:0001942850.420
cell fate specificationGO:0001708720.419
Mouse
branch elongation involved in salivary gland morphogenesisGO:006066720.418
mesenchymal cell differentiation involved in lung developmentGO:006091520.418
embryonic appendage morphogenesisGO:00351131260.416
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.413
embryonic placenta developmentGO:0001892980.408
tissue remodelingGO:00487711020.407
positive regulation of high voltage gated calcium channel activityGO:190184310.406
thyroid hormone generationGO:000659070.406
apoptotic process involved in developmentGO:1902742280.402
Mouse
tissue migrationGO:0090130680.399
forebrain neuron developmentGO:0021884300.397
heart growthGO:0060419450.395
Mouse
negative regulation of glucokinase activityGO:003313240.386
regulation of homeostatic processGO:00328441820.383
cellular modified amino acid metabolic processGO:0006575630.377
regulation of cellular amine metabolic processGO:0033238200.373
metanephric capsule morphogenesisGO:007226510.373
ossificationGO:00015032160.373
insulin secretion involved in cellular response to glucose stimulusGO:0035773360.372
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.370
Human Mouse
microtubule polymerizationGO:0046785120.369
regulation of mitotic cell cycleGO:00073461260.368
renal system pattern specificationGO:007204890.364
apoptotic process involved in outflow tract morphogenesisGO:000327520.363
digestive tract developmentGO:00485651900.363
Mouse
positive regulation of white fat cell proliferationGO:007035210.361
cellular component assembly involved in morphogenesisGO:00109271390.360
Mouse
apoptotic process involved in morphogenesisGO:0060561250.360
Mouse
regulation of angiogenesisGO:0045765810.359
nitrogen compound transportGO:00717052710.359
detection of stimulusGO:0051606840.358
muscle cell differentiationGO:00426922610.358
Mouse
wnt signaling pathwayGO:00160551880.356
Mouse
positive regulation of cell adhesionGO:0045785800.352
regulation of cell motilityGO:20001452360.348
Human
lung secretory cell differentiationGO:0061140130.348
establishment or maintenance of neuroblast polarityGO:004519610.348
ear developmentGO:00435832000.346
Mouse
extracellular structure organizationGO:00430621480.346
development of primary female sexual characteristicsGO:0046545730.344
Rat
diencephalon developmentGO:0021536630.344
regulation of endothelial cell migrationGO:0010594220.343
nephric duct formationGO:007217940.343
pattern specification involved in metanephros developmentGO:007226840.341
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.341
striated muscle cell proliferationGO:0014855390.339
Mouse
camera type eye developmentGO:00430102660.334
mammary gland bud formationGO:006061520.334
negative regulation of transcription by glucoseGO:004501410.331
epithelial mesenchymal cell signalingGO:006068470.331
regulation of white fat cell proliferationGO:007035020.329
metanephros morphogenesisGO:0003338240.324
female somatic sex determinationGO:001910110.324
response to fibroblast growth factorGO:0071774470.324
negative regulation of molecular functionGO:00440922580.323
negative regulation of cell developmentGO:00107211690.323
Human Mouse
cartilage developmentGO:00512161400.323
Mouse
metanephric nephron developmentGO:0072210340.322
endocrine pancreas developmentGO:0031018290.321
Mouse
mammary gland epithelial cell differentiationGO:0060644130.316
male sex differentiationGO:00466611090.315
positive regulation of neuroblast proliferationGO:0002052190.313
embryonic limb morphogenesisGO:00303261260.312
chromatin organizationGO:00063252060.312
hindbrain developmentGO:00309021280.311
regulation of cardiac muscle cell proliferationGO:0060043230.309
Mouse
female sex determinationGO:003023710.306
female genitalia morphogenesisGO:004880730.306
limb morphogenesisGO:00351081490.304
muscle cell fate commitmentGO:0042693110.302
Mouse
epidermis morphogenesisGO:0048730330.302
regulation of wnt signaling pathwayGO:00301111230.298
Mouse
mesenchymal epithelial cell signaling involved in lung developmentGO:006049610.296
blood circulationGO:00080151950.295
Mouse Rat
regulation of vasculature developmentGO:1901342880.295
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.295
multicellular organism growthGO:00352641610.292
positive regulation of response to woundingGO:1903036660.291
neuron deathGO:00709971540.291
primitive streak formationGO:0090009100.290
regulation of embryonic developmentGO:0045995710.290
positive regulation of cell migrationGO:00303351090.289
male anatomical structure morphogenesisGO:009059840.288
neuron apoptotic processGO:00514021420.288
mesangial cell developmentGO:007214340.287
development of primary male sexual characteristicsGO:0046546880.285
regulation of gastrulationGO:0010470160.284
smoothened signaling pathwayGO:00072241050.284
Mouse
hard palate developmentGO:006002250.283
male genitalia morphogenesisGO:004880840.282
paraxial mesoderm developmentGO:0048339180.280
male gamete generationGO:00482322850.280
neuroblast proliferationGO:0007405490.272
ventricular cardiac muscle tissue developmentGO:0003229380.271
Mouse
heart morphogenesisGO:00030071780.270
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.269
Human
ovulation cycleGO:0042698590.268
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.264
negative regulation of hexokinase activityGO:190330040.263
positive regulation of angiogenesisGO:0045766460.260
muscle tissue morphogenesisGO:0060415530.260
Mouse
negative regulation of neuron deathGO:1901215980.259
renal capsule morphogenesisGO:007212810.259
regulation of cell morphogenesis involved in differentiationGO:00107691510.257
Human
regulation of cell adhesionGO:00301551540.257
positive regulation of programmed cell deathGO:00430682180.256
asymmetric stem cell divisionGO:009872230.255
limbic system developmentGO:0021761720.255
regulation of canonical wnt signaling pathwayGO:0060828820.254
Mouse
cell differentiation in hindbrainGO:0021533240.253
blastocyst developmentGO:0001824800.253
renal system developmentGO:00720012250.248
embryonic eye morphogenesisGO:0048048290.248
dopaminergic neuron differentiationGO:0071542140.246
regulation of cardiac muscle tissue developmentGO:0055024310.245
Mouse
cardiac muscle tissue developmentGO:00487381300.244
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.243
specification of organ identityGO:0010092300.241
metanephric capsule formationGO:007226610.236
regulation of epithelial cell migrationGO:0010632350.236
regulation of muscle tissue developmentGO:1901861970.235
Mouse
regulation of cell migrationGO:00303342190.234
Human
regulation of neuron apoptotic processGO:00435231220.233
paraxial mesoderm formationGO:004834160.232
organ inductionGO:0001759210.231
cell maturationGO:00484691270.231
axonogenesisGO:00074092740.230
negative regulation of neuron differentiationGO:00456651010.229
Mouse
regulation of cellular ketone metabolic processGO:0010565660.229
bronchiole morphogenesisGO:006043610.228
hypophysis morphogenesisGO:004885030.227
nuclear transportGO:00511691390.227
positive regulation of ion transmembrane transporter activityGO:0032414150.226
Mouse
retina morphogenesis in camera type eyeGO:0060042450.226
hormone metabolic processGO:0042445860.225
rhythmic processGO:00485111740.224
forebrain regionalizationGO:0021871250.222
fibroblast growth factor receptor signaling pathwayGO:0008543460.220
regulation of kidney developmentGO:0090183400.219
pattern specification involved in kidney developmentGO:006100480.218
spermatogenesisGO:00072832840.218
female gonad developmentGO:0008585710.218
oligodendrocyte differentiationGO:0048709530.217
neuron fate determinationGO:004866490.217
Mouse
ectoderm formationGO:000170530.216
skeletal muscle organ developmentGO:00605381630.216
glomerular endothelium developmentGO:007201120.215
olfactory bulb developmentGO:0021772300.213
mesodermal cell fate commitmentGO:0001710170.208
positive regulation of kidney developmentGO:0090184280.207
kidney mesenchyme developmentGO:0072074140.205
corticotropin hormone secreting cell differentiationGO:006012830.204
apoptotic process involved in heart morphogenesisGO:000327850.204
Mouse
positive regulation of oligodendrocyte differentiationGO:004871490.203
Mouse
somite rostral caudal axis specificationGO:0032525130.201
thyroid hormone metabolic processGO:0042403160.201
vascular wound healingGO:006104230.200
nephrogenic mesenchyme developmentGO:007207630.200
protein localization to nucleusGO:00345041210.200
metanephric capsule specificationGO:007226710.199
somitogenesisGO:0001756690.198
asymmetric neuroblast divisionGO:005505910.194
response to growth factorGO:00708481980.194
Human
endothelium developmentGO:0003158450.193
neuromuscular processGO:0050905990.193
cell cell signaling involved in lung developmentGO:006049510.191
regulation of apoptotic process involved in morphogenesisGO:1902337100.191
amine metabolic processGO:0009308450.190
renal capsule specificationGO:007213010.188
regulation of insulin secretion involved in cellular response to glucose stimulusGO:0061178310.188
neural crest cell developmentGO:0014032480.188
neural tube formationGO:00018411080.188
tube closureGO:0060606910.188
inner ear receptor cell differentiationGO:0060113610.188
actin cytoskeleton organizationGO:00300362200.187
Mouse
aminoglycan metabolic processGO:0006022340.186
embryonic epithelial tube formationGO:00018381300.186
cellular response to glucose stimulusGO:0071333450.186
peptide secretionGO:00027901140.184
positive regulation of cell motilityGO:20001471160.184
outflow tract morphogenesisGO:0003151530.183
Mouse
regulation of heart morphogenesisGO:2000826220.183
renal vesicle inductionGO:007203430.182
cochlea morphogenesisGO:0090103220.182
positive regulation of activin receptor signaling pathwayGO:003292730.182
regulation of cell sizeGO:0008361720.182
development of primary sexual characteristicsGO:00451371430.182
regulation of transcription from rna polymerase ii promoter by glucoseGO:000043030.181
regulation of cell fate specificationGO:0042659100.180
kidney rudiment formationGO:007200330.179
cell proliferation in hindbrainGO:0021534100.179
regulation of cartilage developmentGO:0061035440.179
Mouse
harderian gland developmentGO:007038420.178
carbon catabolite repression of transcriptionGO:004501310.177
negative regulation of transcription from rna polymerase ii promoter by glucoseGO:000043310.175
regulation of thyroid hormone generationGO:200060940.175
positive regulation of epithelial cell migrationGO:0010634190.175
pyramidal neuron developmentGO:002186080.171
regulation of organelle organizationGO:00330432890.171
organic hydroxy compound metabolic processGO:19016152030.170
regulation of osteoblast differentiationGO:0045667670.170
dichotomous subdivision of terminal units involved in ureteric bud branchingGO:006067810.170
negative regulation of nervous system developmentGO:00519611560.170
Mouse
embryonic genitalia morphogenesisGO:003053840.169
adult locomotory behaviorGO:0008344910.168
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.167
odontogenesis of dentin containing toothGO:0042475660.167
Mouse
cerebral cortex developmentGO:0021987860.166
cardiac ventricle developmentGO:0003231830.165
Mouse
trachea cartilage morphogenesisGO:006053540.163
neural crest cell differentiationGO:0014033540.162
positive regulation of apoptotic processGO:00430652170.160
regulation of blood vessel endothelial cell migrationGO:0043535120.159
positive regulation of endothelial cell migrationGO:0010595120.158
positive regulation of mesenchymal cell proliferationGO:0002053330.157
bone developmentGO:00603481200.156
epithelial cell differentiation involved in kidney developmentGO:0035850230.156
cellular carbohydrate metabolic processGO:00442621190.154
regulation of apoptotic signaling pathwayGO:20012331970.154
dichotomous subdivision of an epithelial terminal unitGO:0060600110.153
regulation of cytoplasmic transportGO:19036491120.153
axis elongation involved in somitogenesisGO:009024540.152
negative regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021240.152
fibroblast growth factor receptor signaling pathway involved in mammary gland specificationGO:006059520.151
regulation of detection of glucoseGO:200097010.150
canonical wnt signaling pathwayGO:00600701300.150
Mouse
metanephric nephron morphogenesisGO:0072273190.149
type ii pneumocyte differentiationGO:006051070.149
germ cell developmentGO:00072811850.149
inorganic ion transmembrane transportGO:00986602340.149
Mouse
cell adhesionGO:00071553290.147
regulation of cellular amino acid metabolic processGO:000652150.147
pancreatic pp cell fate commitmentGO:000332920.145
Mouse
epithelial cell migrationGO:0010631630.145
connective tissue developmentGO:00614481790.144
Mouse
positive regulation of cellular amine metabolic processGO:003324050.143
embryonic digestive tract morphogenesisGO:0048557170.142
renal interstitial fibroblast developmentGO:007214150.141
regulation of transcription by glucoseGO:004601530.141
mesenchymal cell developmentGO:0014031930.141
Human
positive regulation of striated muscle tissue developmentGO:0045844310.140
nuclear importGO:0051170950.140
regulation of secretionGO:00510462740.139
regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021140.138
negative regulation of mesodermal cell fate specificationGO:004266230.136
spinal cord developmentGO:0021510810.135
Mouse
white fat cell proliferationGO:007034320.135
metanephric mesenchymal cell differentiationGO:007216230.134
spermatid differentiationGO:00485151150.134
negative regulation of growthGO:0045926990.133
metanephric nephron tubule formationGO:007228940.133
cell proliferation in external granule layerGO:0021924100.133
neuron recognitionGO:0008038250.132
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.132
regulation of defense responseGO:00313472330.131
ectoderm developmentGO:0007398150.128
negative regulation of cell cycleGO:00457861230.126
glucose homeostasisGO:00425931280.126
regulation of neuroblast proliferationGO:1902692270.125
mammary gland morphogenesisGO:0060443540.124
second messenger mediated signalingGO:0019932730.123
positive regulation of immature t cell proliferationGO:003309140.122
hypothalamus developmentGO:0021854160.122
Mouse
regulation of carbohydrate metabolic processGO:0006109750.121
mesodermal cell migrationGO:000807840.121
regulation of hormone secretionGO:0046883880.120
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.119
positive regulation of wound healingGO:0090303170.119
positive regulation of cell migration involved in sprouting angiogenesisGO:009005030.119
pyramidal neuron differentiationGO:002185990.119
renal capsule developmentGO:007212710.118
negative regulation of sterol transportGO:003237240.118
adenohypophysis developmentGO:0021984140.118
olfactory bulb interneuron differentiationGO:0021889120.117
regulation of cellular component sizeGO:00325351210.117
regulation of anatomical structure sizeGO:00900661780.116
regulation of fat cell differentiationGO:0045598810.116
cytokine productionGO:00018163190.116
regulation of neuron deathGO:19012141340.116
neuroepithelial cell differentiationGO:0060563370.116
somatic stem cell maintenanceGO:0035019470.116
retinal bipolar neuron differentiationGO:006004050.115
female genitalia developmentGO:0030540140.115

Nkx2-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.304
endocrine system diseaseDOID:2800.304
thyroid gland diseaseDOID:5000.270
hypothyroidismDOID:145900.270