IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Gars

glycyl-tRNA synthetase

(Aliases: Nmf249,Sgrp23)

Entrez: 353172
Ensembl: ENSMUSG00000029777
UniProtKB: Q9CZD3

Process Predictions
Disease Predictions

Gars biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
trna aminoacylation for protein translation	GO:0006418	1	0.994
trna aminoacylation	GO:0043039	1	0.993
amino acid activation	GO:0043038	1	0.984
trna metabolic process	GO:0006399	11	0.943
translation	GO:0006412	93	0.942
cellular amino acid metabolic process	GO:0006520	103	0.498
spindle assembly involved in mitosis	GO:0090307	4	0.347
ion transmembrane transport	GO:0034220	361	0.242
cellular amine metabolic process	GO:0044106	44	0.215
microtubule cytoskeleton organization involved in mitosis	GO:1902850	4	0.185
folic acid containing compound metabolic process	GO:0006760	3	0.165
nucleobase containing small molecule metabolic process	GO:0055086	352	0.154	Human
cation transport	GO:0006812	399	0.146
neuron apoptotic process	GO:0051402	142	0.128
amine metabolic process	GO:0009308	45	0.120
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.112
nucleoside triphosphate metabolic process	GO:0009141	230	0.109
regulation of hydrolase activity	GO:0051336	246	0.108
protein folding	GO:0006457	28	0.105
nucleotide metabolic process	GO:0009117	332	0.100	Human
mitotic cell cycle	GO:0000278	195	0.099
regulation of translation	GO:0006417	71	0.084
regulation of phosphatidylcholine biosynthetic process	GO:2001245	2	0.083
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.081
nadph regeneration	GO:0006740	2	0.070
molting cycle	GO:0042303	90	0.070
binding of sperm to zona pellucida	GO:0007339	34	0.070
negative regulation of protein metabolic process	GO:0051248	282	0.069
response to acid chemical	GO:0001101	111	0.068
branched chain amino acid transport	GO:0015803	2	0.067
cation transmembrane transport	GO:0098655	266	0.064
dna repair	GO:0006281	107	0.063
coenzyme metabolic process	GO:0006732	52	0.063
organophosphate catabolic process	GO:0046434	232	0.061
sperm egg recognition	GO:0035036	37	0.059
transmembrane transport	GO:0055085	412	0.055
cell type specific apoptotic process	GO:0097285	268	0.055
regulation of translational elongation	GO:0006448	4	0.053
dna dealkylation	GO:0035510	11	0.052
cytoplasmic transport	GO:0016482	234	0.051
neuron death	GO:0070997	154	0.047
ribose phosphate metabolic process	GO:0019693	291	0.047
response to amino acid	GO:0043200	37	0.047
microtubule based process	GO:0007017	236	0.046
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.046
ribonucleoside catabolic process	GO:0042454	206	0.046
pentose phosphate shunt	GO:0006098	2	0.045
atp metabolic process	GO:0046034	75	0.045
carbohydrate derivative catabolic process	GO:1901136	231	0.045
ribonucleotide catabolic process	GO:0009261	208	0.045
response to organonitrogen compound	GO:0010243	246	0.045
nucleoside metabolic process	GO:0009116	246	0.044
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.042
negative regulation of cellular protein metabolic process	GO:0032269	247	0.042
organic acid transport	GO:0015849	101	0.040
negative regulation of neuron death	GO:1901215	98	0.040
positive regulation of hydrolase activity	GO:0051345	148	0.040
hexose catabolic process	GO:0019320	3	0.038
nucleoside phosphate metabolic process	GO:0006753	338	0.038	Human
glucose catabolic process	GO:0006007	3	0.038
nitrogen compound transport	GO:0071705	271	0.037
glycosyl compound metabolic process	GO:1901657	246	0.036
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.036
dephosphorylation	GO:0016311	129	0.036
purine containing compound catabolic process	GO:0072523	213	0.035
organophosphate biosynthetic process	GO:0090407	122	0.035	Human
purine ribonucleotide metabolic process	GO:0009150	290	0.034
regulation of neuron death	GO:1901214	134	0.033
inorganic cation transmembrane transport	GO:0098662	207	0.032
nucleoside triphosphate catabolic process	GO:0009143	205	0.032
epidermis development	GO:0008544	187	0.031
carbohydrate biosynthetic process	GO:0016051	74	0.031
regulation of cellular ketone metabolic process	GO:0010565	66	0.031
l alpha amino acid transmembrane transport	GO:1902475	23	0.031
cellular response to dna damage stimulus	GO:0006974	207	0.030
methionine transport	GO:0015821	1	0.030
negative regulation of cell development	GO:0010721	169	0.030
cellular nitrogen compound catabolic process	GO:0044270	280	0.030
anion transport	GO:0006820	177	0.030
positive regulation of cellular amine metabolic process	GO:0033240	5	0.029
purine ribonucleoside catabolic process	GO:0046130	205	0.029
purine containing compound metabolic process	GO:0072521	311	0.028
monosaccharide metabolic process	GO:0005996	106	0.028
neuromuscular process controlling balance	GO:0050885	59	0.027
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.027
negative regulation of cellular amine metabolic process	GO:0033239	1	0.027
neuromuscular process	GO:0050905	99	0.026
protein polymerization	GO:0051258	57	0.026
small gtpase mediated signal transduction	GO:0007264	97	0.026
cellular response to acid chemical	GO:0071229	68	0.026
anion transmembrane transport	GO:0098656	71	0.026
organelle assembly	GO:0070925	177	0.026
negative regulation of neuron apoptotic process	GO:0043524	92	0.026
regulation of transmembrane transport	GO:0034762	128	0.026
nucleoside catabolic process	GO:0009164	206	0.025
glycosyl compound catabolic process	GO:1901658	206	0.025
regulation of ion transport	GO:0043269	215	0.025
positive regulation of apoptotic process	GO:0043065	217	0.025
positive regulation of peptidase activity	GO:0010952	49	0.024
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.024
translational initiation	GO:0006413	24	0.023
protein modification by small protein conjugation or removal	GO:0070647	207	0.023
regulation of cellular amine metabolic process	GO:0033238	20	0.023
apoptotic signaling pathway	GO:0097190	306	0.023
purine ribonucleoside metabolic process	GO:0046128	241	0.023
cellular response to organonitrogen compound	GO:0071417	145	0.023
carbohydrate derivative biosynthetic process	GO:1901137	183	0.022
nucleoside phosphate catabolic process	GO:1901292	222	0.022
purine nucleoside catabolic process	GO:0006152	205	0.022
fertilization	GO:0009566	127	0.022
cellular protein catabolic process	GO:0044257	155	0.022
positive regulation of cellular catabolic process	GO:0031331	148	0.022
cristae formation	GO:0042407	3	0.022
purine ribonucleotide catabolic process	GO:0009154	208	0.021
protein catabolic process	GO:0030163	221	0.021
purine nucleoside metabolic process	GO:0042278	241	0.021
negative regulation of protein modification process	GO:0031400	163	0.021
cellular ketone metabolic process	GO:0042180	84	0.021
hair cycle	GO:0042633	90	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.021
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.021
organelle disassembly	GO:1903008	2	0.021
nuclear transport	GO:0051169	139	0.021
microtubule cytoskeleton organization	GO:0000226	157	0.021
regulation of neuron apoptotic process	GO:0043523	122	0.020
dna metabolic process	GO:0006259	303	0.020
phosphatidylethanolamine metabolic process	GO:0046337	2	0.020
negative regulation of cell proliferation	GO:0008285	296	0.020
positive regulation of protein modification process	GO:0031401	299	0.020
nucleotide catabolic process	GO:0009166	217	0.020
membrane organization	GO:0061024	245	0.020
transmission of nerve impulse	GO:0019226	76	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
regulation of cellular amino acid metabolic process	GO:0006521	5	0.019
negative regulation of phosphorus metabolic process	GO:0010563	184	0.019
germ cell development	GO:0007281	185	0.019
divalent metal ion transport	GO:0070838	172	0.019
regulation of ion transmembrane transport	GO:0034765	119	0.019
carbohydrate metabolic process	GO:0005975	230	0.019
regulation of endopeptidase activity	GO:0052548	89	0.019
multicellular organism growth	GO:0035264	161	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.018
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.018
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.018
negative regulation of protein phosphorylation	GO:0001933	126	0.018
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
response to oxidative stress	GO:0006979	123	0.018
cellular biogenic amine metabolic process	GO:0006576	28	0.018
regulation of protein complex assembly	GO:0043254	83	0.018
organelle localization	GO:0051640	179	0.017
heterocycle catabolic process	GO:0046700	280	0.017
heart morphogenesis	GO:0003007	178	0.017
negative regulation of alcohol biosynthetic process	GO:1902931	4	0.017
rna modification	GO:0009451	20	0.017
forebrain development	GO:0030900	302	0.017
actin filament organization	GO:0007015	113	0.017
proteasomal protein catabolic process	GO:0010498	98	0.017
skin development	GO:0043588	220	0.016
ribonucleotide metabolic process	GO:0009259	291	0.016
ribose phosphate biosynthetic process	GO:0046390	59	0.016
mitochondrion organization	GO:0007005	134	0.016
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000463	1	0.016
hair follicle development	GO:0001942	85	0.016
regulation of cellular catabolic process	GO:0031329	242	0.016
toxin transport	GO:1901998	38	0.016
hexose biosynthetic process	GO:0019319	39	0.016
response to endoplasmic reticulum stress	GO:0034976	53	0.016
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	23	0.016
telencephalon development	GO:0021537	186	0.016
multicellular organismal signaling	GO:0035637	91	0.015
cell adhesion	GO:0007155	329	0.015
cytoplasmic translational initiation	GO:0002183	3	0.015
cellular response to cytokine stimulus	GO:0071345	189	0.015
t cell activation	GO:0042110	289	0.015
cofactor metabolic process	GO:0051186	80	0.015
cellular response to amino acid stimulus	GO:0071230	29	0.015
single fertilization	GO:0007338	82	0.015
response to light stimulus	GO:0009416	135	0.015
epithelial cell proliferation	GO:0050673	174	0.015
positive regulation of cell death	GO:0010942	224	0.015
inorganic ion transmembrane transport	GO:0098660	234	0.015
regulation of membrane potential	GO:0042391	192	0.014
negative regulation of molecular function	GO:0044092	258	0.014
protein modification by small protein conjugation	GO:0032446	187	0.014
histone modification	GO:0016570	159	0.014
gland development	GO:0048732	330	0.014
myotube differentiation	GO:0014902	105	0.014
leukocyte migration	GO:0050900	124	0.014
aromatic compound catabolic process	GO:0019439	286	0.014
monosaccharide biosynthetic process	GO:0046364	44	0.014
cellular lipid metabolic process	GO:0044255	323	0.014
cell cell recognition	GO:0009988	44	0.014
nucleobase containing compound transport	GO:0015931	27	0.014
mitochondrial translation	GO:0032543	4	0.014
cellular protein complex assembly	GO:0043623	116	0.013
protein import	GO:0017038	101	0.013
positive regulation of protein catabolic process	GO:0045732	60	0.013
respiratory system development	GO:0060541	190	0.013
response to monosaccharide	GO:0034284	67	0.013
rhythmic process	GO:0048511	174	0.013
cellular modified amino acid metabolic process	GO:0006575	63	0.013
gonad development	GO:0008406	141	0.013
mrna transport	GO:0051028	13	0.013
nucleoside monophosphate catabolic process	GO:0009125	59	0.013
organic hydroxy compound metabolic process	GO:1901615	203	0.013
negative regulation of calcium ion transmembrane transporter activity	GO:1901020	1	0.013
cellular response to gonadotropin stimulus	GO:0071371	4	0.013
protein palmitoylation	GO:0018345	14	0.013
regulation of neuron projection development	GO:0010975	169	0.013
negative regulation of epithelial cell proliferation	GO:0050680	64	0.013
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.013
single organism nuclear import	GO:1902593	95	0.013
phospholipid metabolic process	GO:0006644	87	0.013
sensory perception	GO:0007600	245	0.013
protein complex disassembly	GO:0043241	40	0.013
positive regulation of mapk cascade	GO:0043410	170	0.013
sensory organ morphogenesis	GO:0090596	242	0.013
divalent inorganic cation transport	GO:0072511	178	0.012
negative regulation of phosphate metabolic process	GO:0045936	184	0.012
muscle cell differentiation	GO:0042692	261	0.012
neuronal action potential	GO:0019228	54	0.012
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.012
calcium ion transport	GO:0006816	159	0.012
myeloid leukocyte differentiation	GO:0002573	119	0.012
cellular homeostasis	GO:0019725	240	0.012
organonitrogen compound catabolic process	GO:1901565	264	0.012
macromolecule catabolic process	GO:0009057	281	0.012
alpha amino acid metabolic process	GO:1901605	59	0.012
regulation of neuron differentiation	GO:0045664	281	0.012
alcohol metabolic process	GO:0006066	116	0.012
cellular response to lipid	GO:0071396	145	0.012
amino acid transmembrane transport	GO:0003333	37	0.012
positive regulation of endopeptidase activity	GO:0010950	43	0.011
response to extracellular stimulus	GO:0009991	127	0.011
negative regulation of intracellular signal transduction	GO:1902532	167	0.011
response to nutrient levels	GO:0031667	109	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.011
ossification	GO:0001503	216	0.011
response to inorganic substance	GO:0010035	96	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
atp catabolic process	GO:0006200	55	0.011
regulation of transporter activity	GO:0032409	57	0.011
nucleoside monophosphate metabolic process	GO:0009123	85	0.011
regulation of leukocyte differentiation	GO:1902105	159	0.011
regulation of peptidase activity	GO:0052547	96	0.011
protein maturation	GO:0051604	176	0.011
carboxylic acid biosynthetic process	GO:0046394	86	0.011
cell growth	GO:0016049	130	0.011
regulation of homeostatic process	GO:0032844	182	0.011
multicellular organismal homeostasis	GO:0048871	164	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.011
trna modification	GO:0006400	9	0.011
ubiquitin dependent protein catabolic process	GO:0006511	129	0.011
negative regulation of phosphorylation	GO:0042326	166	0.011
organic hydroxy compound transport	GO:0015850	93	0.011
purine nucleotide metabolic process	GO:0006163	302	0.011
regulation of intracellular protein transport	GO:0033157	82	0.011
purine nucleotide catabolic process	GO:0006195	211	0.011
organelle fission	GO:0048285	170	0.011
nuclear division	GO:0000280	158	0.011
necrotic cell death	GO:0070265	30	0.011
nuclear export	GO:0051168	34	0.010
regulation of wnt signaling pathway	GO:0030111	123	0.010
regulation of establishment of protein localization	GO:0070201	181	0.010
action potential	GO:0001508	78	0.010
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.010
monocarboxylic acid metabolic process	GO:0032787	191	0.010
intrinsic apoptotic signaling pathway	GO:0097193	132	0.010
cellular response to follicle stimulating hormone stimulus	GO:0071372	1	0.010
regulation of organelle organization	GO:0033043	289	0.010
regulation of protein catabolic process	GO:0042176	108	0.010
single organism cell adhesion	GO:0098602	156	0.010
response to peptide hormone	GO:0043434	127	0.010

Gars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
nervous system disease	DOID:863	0.331	Human
disease of anatomical entity	DOID:7	0.331	Human
neuropathy	DOID:870	0.261	Human
charcot marie tooth disease	DOID:10595	0.197	Human
charcot marie tooth disease type 2	DOID:0050539	0.197	Human
neuromuscular disease	DOID:440	0.197	Human
disease of cellular proliferation	DOID:14566	0.013
central nervous system disease	DOID:331	0.013	Human
neurodegenerative disease	DOID:1289	0.013	Human
sensory system disease	DOID:0050155	0.011

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