Mus musculus

149 known processes

Kdm3a

lysine (K)-specific demethylase 3A

(Aliases: Jmjd1,Tsga,JHDM2a,mKIAA0742,TGSA,Jmjd1a,C230043E16Rik,KDM2A,1700105C21Rik)

Kdm3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
covalent chromatin modificationGO:00165691630.311
transcription from rna polymerase iii promoterGO:000638330.304
regulation of transcription from rna polymerase iii promoterGO:000635920.211
erythrocyte differentiationGO:0030218880.160
dna metabolic processGO:00062593030.152
protein methylationGO:0006479810.137
rna processingGO:00063961050.121
histone modificationGO:00165701590.117
response to retinoic acidGO:0032526560.114
peptidyl amino acid modificationGO:00181933360.109
gluconeogenesisGO:0006094390.104
histone methylationGO:0016571710.097
cellular ketone metabolic processGO:0042180840.091
cellular response to dna damage stimulusGO:00069742070.085
regulation of innate immune responseGO:0045088910.075
regulation of cellular ketone metabolic processGO:0010565660.071
cellular carbohydrate metabolic processGO:00442621190.071
negative regulation of cell proliferationGO:00082852960.071
t cell proliferationGO:00420981200.069
myeloid cell differentiationGO:00300992330.068
carbohydrate metabolic processGO:00059752300.066
peptidyl serine modificationGO:0018209830.065
chromatin modificationGO:00165681870.063
immune effector processGO:00022523210.061
regulation of histone modificationGO:0031056560.061
glucose metabolic processGO:0006006920.059
regulation of hydrolase activityGO:00513362460.059
regulation of cellular carbohydrate metabolic processGO:0010675750.058
regulation of carbohydrate biosynthetic processGO:0043255400.057
chromatin organizationGO:00063252060.056
regulation of cellular amino acid metabolic processGO:000652150.056
negative regulation of cellular carbohydrate metabolic processGO:0010677190.055
macromolecule methylationGO:00434141200.052
macromolecule catabolic processGO:00090572810.050
regulation of protein stabilityGO:0031647520.048
regulation of gluconeogenesisGO:0006111300.048
dna repairGO:00062811070.048
homeostasis of number of cellsGO:00488722100.048
negative regulation of cellular component organizationGO:00511291940.048
spermatid differentiationGO:00485151150.047
regulation of glucose metabolic processGO:0010906600.046
negative regulation of molecular functionGO:00440922580.044
methylationGO:00322591340.044
myeloid leukocyte differentiationGO:00025731190.043
regulation of chromatin silencingGO:003193520.043
protein catabolic processGO:00301632210.042
regulation of lymphocyte activationGO:00512492400.042
regulation of t cell activationGO:00508631700.042
cellular amino acid metabolic processGO:00065201030.042
t cell activationGO:00421102890.039
amine metabolic processGO:0009308450.038
peptidyl lysine modificationGO:0018205770.038
regulation of cellular amine metabolic processGO:0033238200.037
negative regulation of gluconeogenesisGO:004572190.037
protein modification by small protein conjugation or removalGO:00706472070.037
negative regulation of protein modification processGO:00314001630.037
rna 3 end processingGO:0031123200.035
positive regulation of protein modification processGO:00314012990.035
protein autophosphorylationGO:0046777610.035
cell growthGO:00160491300.035
cation transportGO:00068123990.035
negative regulation of protein metabolic processGO:00512482820.035
ion transmembrane transportGO:00342203610.034
male gamete generationGO:00482322850.034
negative regulation of cellular protein metabolic processGO:00322692470.034
monosaccharide biosynthetic processGO:0046364440.034
response to acid chemicalGO:00011011110.034
response to organic cyclic compoundGO:00140701980.033
cell type specific apoptotic processGO:00972852680.033
carbohydrate derivative biosynthetic processGO:19011371830.033
cellular amine metabolic processGO:0044106440.032
regulation of cellular response to stressGO:00801351590.032
leukocyte differentiationGO:00025213420.032
spermatogenesisGO:00072832840.032
positive regulation of leukocyte differentiationGO:1902107860.032
divalent inorganic cation homeostasisGO:00725071380.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.032
positive regulation of cell deathGO:00109422240.032
regulation of ossificationGO:00302781120.032
regulation of organelle organizationGO:00330432890.031
regulation of defense responseGO:00313472330.030
appendage developmentGO:00487361660.030
protein modification by small protein conjugationGO:00324461870.030
cytokine productionGO:00018163190.030
hexose metabolic processGO:0019318980.029
cellular response to nutrient levelsGO:0031669640.029
hexose biosynthetic processGO:0019319390.029
protein ubiquitinationGO:00165671710.029
negative regulation of cellular amino acid metabolic processGO:004576300.028
rna splicingGO:0008380540.028
regulation of carbohydrate metabolic processGO:0006109750.028
regulation of cell activationGO:00508652890.028
defense response to other organismGO:00985421970.028
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.027
posttranscriptional regulation of gene expressionGO:00106081550.027
nucleotide transmembrane transportGO:190167920.027
leukocyte proliferationGO:00706611720.027
cellular macromolecule catabolic processGO:00442652060.027
post embryonic hemopoiesisGO:003516640.027
activation of innate immune responseGO:0002218560.027
response to radiationGO:00093141650.027
multicellular organism growthGO:00352641610.027
metal ion homeostasisGO:00550651890.027
negative regulation of growthGO:0045926990.027
cellular response to external stimulusGO:0071496880.027
innate immune responseGO:00450871570.026
eye photoreceptor cell developmentGO:0042462310.026
positive regulation of programmed cell deathGO:00430682180.026
neuronal action potentialGO:0019228540.026
viral processGO:0016032410.026
asymmetric stem cell divisionGO:009872230.026
regulation of chromatin organizationGO:1902275570.025
modification dependent protein catabolic processGO:00199411330.025
organic cyclic compound catabolic processGO:19013612950.025
placenta developmentGO:00018901400.025
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.025
protein alkylationGO:0008213810.024
mesenchymal cell developmentGO:0014031930.024
regulation of cell cycle processGO:00105641600.024
mrna metabolic processGO:0016071840.024
negative regulation of hydrolase activityGO:0051346710.024
positive regulation of apoptotic processGO:00430652170.023
peptidyl tyrosine phosphorylationGO:00181081430.023
axonogenesisGO:00074092740.023
regulation of lymphocyte proliferationGO:00506701170.023
sequestering of metal ionGO:0051238190.023
negative regulation of cell cycleGO:00457861230.023
negative regulation of lymphocyte activationGO:0051250910.022
negative regulation of carbohydrate metabolic processGO:0045912190.022
calcium ion homeostasisGO:00550741270.022
carbohydrate biosynthetic processGO:0016051740.022
regulation of apoptotic signaling pathwayGO:20012331970.022
protein polyubiquitinationGO:0000209330.022
peptidyl tyrosine modificationGO:00182121450.022
transmembrane transportGO:00550854120.022
histone lysine methylationGO:0034968500.022
transmission of nerve impulseGO:0019226760.021
regulation of cytokine productionGO:00018172660.021
negative regulation of lymphocyte proliferationGO:0050672450.021
nuclear transcribed mrna catabolic processGO:0000956160.021
intrinsic apoptotic signaling pathwayGO:00971931320.021
immune response activating signal transductionGO:00027571160.021
response to peptideGO:19016521360.020
regulation of protein localizationGO:00328802310.020
positive regulation of cytokine productionGO:00018191740.020
negative regulation of t cell activationGO:0050868650.020
negative regulation of immune system processGO:00026832090.020
negative regulation of cell cycle phase transitionGO:1901988480.020
divalent inorganic cation transportGO:00725111780.020
negative regulation of histone h3 k9 methylationGO:005157340.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.019
cell maturationGO:00484691270.019
negative regulation of organelle organizationGO:0010639900.019
regulation of lymphocyte apoptotic processGO:0070228410.019
negative regulation of cellular amine metabolic processGO:003323910.019
regulation of histone methylationGO:0031060300.019
actin filament organizationGO:00070151130.019
negative regulation of t cell proliferationGO:0042130380.019
negative regulation of bmp signaling pathwayGO:0030514350.019
cellular homeostasisGO:00197252400.019
response to organonitrogen compoundGO:00102432460.019
leukocyte apoptotic processGO:0071887710.019
developmental growth involved in morphogenesisGO:00605601380.018
peptidyl threonine modificationGO:0018210310.018
regulation of protein catabolic processGO:00421761080.018
immune response regulating signaling pathwayGO:00027641250.018
canonical wnt signaling pathwayGO:00600701300.018
stem cell differentiationGO:00488632680.018
lymphocyte proliferationGO:00466511640.018
negative regulation of cell activationGO:00508661110.018
cellular response to lipidGO:00713961450.018
action potentialGO:0001508780.018
monosaccharide metabolic processGO:00059961060.018
positive regulation of defense responseGO:00313491240.018
cytoplasmic transportGO:00164822340.018
positive regulation of histone modificationGO:0031058280.018
response to transforming growth factor betaGO:0071559880.018
dna integrity checkpointGO:0031570280.017
cation transmembrane transportGO:00986552660.017
negative regulation of leukocyte proliferationGO:0070664460.017
fat cell differentiationGO:00454441600.017
lung developmentGO:00303241640.017
positive regulation of innate immune responseGO:0045089800.017
neuron apoptotic processGO:00514021420.017
osteoclast differentiationGO:0030316620.017
regulation of cell cycleGO:00517262810.017
response to nutrient levelsGO:00316671090.017
cellular protein catabolic processGO:00442571550.017
regulation of t cell proliferationGO:0042129920.017
peptidyl threonine phosphorylationGO:0018107310.017
urogenital system developmentGO:00016552610.017
regulation of chromatin modificationGO:1903308570.017
negative regulation of chromatin silencingGO:003193610.017
photoreceptor cell differentiationGO:0046530520.017
activation of immune responseGO:00022531380.016
mesenchymal cell differentiationGO:00487621070.016
positive regulation of cellular amine metabolic processGO:003324050.016
positive regulation of apoptotic signaling pathwayGO:2001235950.016
cellular divalent inorganic cation homeostasisGO:00725031270.016
apoptotic signaling pathwayGO:00971903060.016
regulation of myeloid leukocyte differentiationGO:0002761580.016
positive regulation of organelle organizationGO:00106381280.016
asymmetric neuroblast divisionGO:005505910.016
internal protein amino acid acetylationGO:0006475420.016
developmental maturationGO:00217001930.016
regulation of response to dna damage stimulusGO:2001020340.016
cellular response to organic cyclic compoundGO:0071407870.016
mitotic cell cycleGO:00002781950.016
nuclear divisionGO:00002801580.016
cellular response to steroid hormone stimulusGO:0071383330.016
dna alkylationGO:0006305430.016
positive regulation of myeloid cell differentiationGO:0045639430.015
regulation of myeloid cell differentiationGO:0045637960.015
negative regulation of mitotic cell cycleGO:0045930580.015
cellular metal ion homeostasisGO:00068751510.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.015
regulation of cell migrationGO:00303342190.015
gland developmentGO:00487323300.015
response to peptide hormoneGO:00434341270.015
regulation of sequence specific dna binding transcription factor activityGO:00510901060.015
transforming growth factor beta receptor signaling pathwayGO:0007179710.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
heterocycle catabolic processGO:00467002800.014
organelle localizationGO:00516401790.014
regulation of androgen receptor signaling pathwayGO:006076530.014
sequestering of calcium ionGO:0051208180.014
cellular response to organonitrogen compoundGO:00714171450.014
myeloid cell homeostasisGO:00022621140.014
kidney developmentGO:00018222130.014
regulation of osteoblast differentiationGO:0045667670.014
stem cell developmentGO:00488642190.014
cell substrate adhesionGO:00315891300.014
regulation of metal ion transportGO:00109591060.014
regulation of transcription from rna polymerase ii promoter by galactoseGO:000043110.014
leukocyte homeostasisGO:0001776790.014
gall bladder developmentGO:006101020.014
positive regulation of protein catabolic processGO:0045732600.014
actin cytoskeleton organizationGO:00300362200.014
cation homeostasisGO:00550802120.014
rna catabolic processGO:0006401290.013
regulation of intracellular transportGO:00323861590.013
regulation of system processGO:00440572000.013
photoreceptor cell developmentGO:0042461400.013
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377430.013
organophosphate biosynthetic processGO:00904071220.013
negative regulation of homeostatic processGO:0032845710.013
positive regulation of protein phosphorylationGO:00019342420.013
response to extracellular stimulusGO:00099911270.013
regulation of cell growthGO:0001558910.013
endocytosisGO:00068971680.013
peptidyl serine phosphorylationGO:0018105740.013
negative regulation of cell cycle processGO:0010948690.013
actin filament based movementGO:0030048230.013
demethylationGO:0070988230.013
Human
positive regulation of cellular amino acid metabolic processGO:004576430.013
regulation of leukocyte proliferationGO:00706631210.013
negative regulation of mitotic cell cycle phase transitionGO:1901991450.013
viral gene expressionGO:001908030.013
response to oxygen levelsGO:0070482620.013
rho protein signal transductionGO:0007266320.013
muscle system processGO:00030121410.013
cellular response to vitaminGO:007129520.013
pigmentationGO:0043473710.013
carbon catabolite regulation of transcriptionGO:004599040.013
multicellular organismal signalingGO:0035637910.013
regulation of hormone levelsGO:00108172110.012
sensory perceptionGO:00076002450.012
genetic imprintingGO:0071514270.012
epithelial tube morphogenesisGO:00605623030.012
forebrain developmentGO:00309003020.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
positive regulation of chromosome organizationGO:2001252330.012
regulation of peptidase activityGO:0052547960.012
response to light stimulusGO:00094161350.012
ossificationGO:00015032160.012
regulation of rna splicingGO:0043484370.012
response to insulinGO:00328681000.012
histone acetylationGO:0016573410.012
i kappab kinase nf kappab signalingGO:0007249850.012
regulation of membrane potentialGO:00423911920.012
lymphocyte homeostasisGO:0002260640.012
regulation of mapk cascadeGO:00434082480.012
negative regulation of histone modificationGO:0031057180.012
divalent metal ion transportGO:00708381720.012
aromatic compound catabolic processGO:00194392860.012
positive regulation of chromatin modificationGO:1903310280.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
regulation of response to alcoholGO:190141920.012
locomotory behaviorGO:00076261950.012
epithelial tube formationGO:00721751300.012
b cell proliferationGO:0042100530.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
negative regulation of phosphate metabolic processGO:00459361840.012
regulation of viral transcriptionGO:004678230.012
b cell activationGO:00421131610.012
inorganic ion transmembrane transportGO:00986602340.012
entry into cell of other organism involved in symbiotic interactionGO:0051806150.011
inorganic cation transmembrane transportGO:00986622070.011
blood vessel morphogenesisGO:00485142850.011
striated muscle tissue developmentGO:00147062930.011
response to vitamin dGO:003328030.011
establishment or maintenance of cytoskeleton polarityGO:003095220.011
digestive tract developmentGO:00485651900.011
development of primary sexual characteristicsGO:00451371430.011
regulation of cellular catabolic processGO:00313292420.011
pharynx developmentGO:006046510.011
neuron deathGO:00709971540.011
rna splicing via transesterification reactionsGO:0000375430.011
wound healingGO:00420601570.011
histone h3 k9 methylationGO:0051567170.011
mitotic chromosome condensationGO:000707610.011
regulation of organ morphogenesisGO:20000271440.011
regulation of ion transportGO:00432692150.011
muscle cell differentiationGO:00426922610.011
cell cycle checkpointGO:0000075470.011
organic hydroxy compound metabolic processGO:19016152030.011
regulation of establishment of protein localizationGO:00702011810.011
inflammatory responseGO:00069542440.011
regulation of inflammatory responseGO:00507271470.011
glycoprotein metabolic processGO:00091001160.011
b cell homeostasisGO:0001782340.011
negative regulation of histone methylationGO:0031061100.011
response to steroid hormoneGO:0048545560.011
lymphocyte apoptotic processGO:0070227540.010
regulation of cytoskeleton organizationGO:00514931220.010
sensory organ morphogenesisGO:00905962420.010
respiratory tube developmentGO:00303231670.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
positive regulation of peptidase activityGO:0010952490.010
regulation of cellular response to growth factor stimulusGO:0090287820.010
negative regulation of gene silencingGO:006096920.010
nitrogen compound transportGO:00717052710.010
cellular response to abiotic stimulusGO:0071214560.010
ubiquitin dependent protein catabolic processGO:00065111290.010
renal system developmentGO:00720012250.010
neural precursor cell proliferationGO:00613511210.010
protein maturationGO:00516041760.010

Kdm3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.041
disease of cellular proliferationDOID:1456600.041
cancerDOID:16200.041
intestinal cancerDOID:1015500.019
colorectal cancerDOID:925600.019
colon cancerDOID:21900.019
gastrointestinal system cancerDOID:311900.019
large intestine cancerDOID:567200.019
thyroid cancerDOID:178100.015
endocrine gland cancerDOID:17000.015
papillary thyroid carcinomaDOID:396900.015
thyroid carcinomaDOID:396300.015
disease of anatomical entityDOID:700.010
nervous system diseaseDOID:86300.010