IMP: Integrative Multi-species Prediction

Mus musculus

21 known processes

Elp2

elongation protein 2 homolog (S. cerevisiae)

(Aliases: StIP1,Epl2,Statip1,AU023723)

Ensembl: ENSMUSG00000024271
Entrez: 58523
UniProtKB: Q91WG4

Process Predictions
Disease Predictions

Elp2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mrna processing	GO:0006397	63	0.502
rna 3 end processing	GO:0031123	20	0.206
ncrna 3 end processing	GO:0043628	2	0.204
mrna 3 end processing	GO:0031124	16	0.161
dna repair	GO:0006281	107	0.085
cellular hyperosmotic salinity response	GO:0071475	0	0.074
organelle fission	GO:0048285	170	0.072
mrna metabolic process	GO:0016071	84	0.071
cellular nitrogen compound catabolic process	GO:0044270	280	0.053
rna processing	GO:0006396	105	0.052	Yeast
cellular amino acid metabolic process	GO:0006520	103	0.046
mrna transport	GO:0051028	13	0.044
chromatin organization	GO:0006325	206	0.041
nucleic acid transport	GO:0050657	18	0.040
snorna metabolic process	GO:0016074	1	0.038
trna wobble uridine modification	GO:0002098	2	0.037	Yeast
ncrna processing	GO:0034470	26	0.035	Yeast
nuclear export	GO:0051168	34	0.035
dna templated transcription termination	GO:0006353	4	0.034
chromatin modification	GO:0016568	187	0.034
cellular response to dna damage stimulus	GO:0006974	207	0.031
regulation of cellular amine metabolic process	GO:0033238	20	0.031
dna metabolic process	GO:0006259	303	0.030
nuclear division	GO:0000280	158	0.030
positive regulation of dna templated transcription elongation	GO:0032786	2	0.029
regulation of cellular ketone metabolic process	GO:0010565	66	0.029
viral process	GO:0016032	41	0.029
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.029
cellular amine metabolic process	GO:0044106	44	0.028
cellular macromolecule catabolic process	GO:0044265	206	0.027
posttranscriptional regulation of gene expression	GO:0010608	155	0.027
positive regulation of cellular amine metabolic process	GO:0033240	5	0.027
cell type specific apoptotic process	GO:0097285	268	0.027
mrna splicing via spliceosome	GO:0000398	43	0.026
interspecies interaction between organisms	GO:0044419	83	0.026
positive regulation of cell death	GO:0010942	224	0.026
somatic diversification of immune receptors	GO:0002200	53	0.026
microtubule based process	GO:0007017	236	0.025
trna wobble base modification	GO:0002097	2	0.025	Yeast
immune effector process	GO:0002252	321	0.024
regulation of cellular amino acid metabolic process	GO:0006521	5	0.024
action potential	GO:0001508	78	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
double strand break repair	GO:0006302	48	0.024
meiotic nuclear division	GO:0007126	115	0.023
protein modification by small protein conjugation or removal	GO:0070647	207	0.022	Yeast
production of molecular mediator of immune response	GO:0002440	103	0.020
chemotaxis	GO:0006935	247	0.020
maintenance of location	GO:0051235	89	0.020
amine metabolic process	GO:0009308	45	0.019
cation transmembrane transport	GO:0098655	266	0.019
small gtpase mediated signal transduction	GO:0007264	97	0.019
methylation	GO:0032259	134	0.018
cytoplasmic transport	GO:0016482	234	0.018
engulfment of apoptotic cell	GO:0043652	3	0.018
multicellular organismal signaling	GO:0035637	91	0.018
cellular ketone metabolic process	GO:0042180	84	0.018
positive regulation of nervous system development	GO:0051962	221	0.018
rna interference	GO:0016246	2	0.017
viral life cycle	GO:0019058	36	0.017
heterocycle catabolic process	GO:0046700	280	0.017
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.016
nitrogen compound transport	GO:0071705	271	0.016
epithelial tube morphogenesis	GO:0060562	303	0.016
rna transport	GO:0050658	18	0.016
receptor mediated endocytosis	GO:0006898	51	0.016
protein dna complex subunit organization	GO:0071824	28	0.016
neuronal action potential	GO:0019228	54	0.016
nucleobase containing compound transport	GO:0015931	27	0.015
b cell activation	GO:0042113	161	0.015
regulation of cell cycle	GO:0051726	281	0.015
gene silencing by mirna	GO:0035195	10	0.015
intrinsic apoptotic signaling pathway	GO:0097193	132	0.015
somatic cell dna recombination	GO:0016444	51	0.015
somatic hypermutation of immunoglobulin genes	GO:0016446	7	0.014
spermatogenesis	GO:0007283	284	0.014
rna splicing	GO:0008380	54	0.014
purine nucleoside metabolic process	GO:0042278	241	0.014
ribonucleoprotein complex subunit organization	GO:0071826	28	0.014
covalent chromatin modification	GO:0016569	163	0.014
macromolecule methylation	GO:0043414	120	0.014
rna phosphodiester bond hydrolysis	GO:0090501	19	0.014
macromolecule catabolic process	GO:0009057	281	0.013
histone modification	GO:0016570	159	0.013
regulation of cellular response to stress	GO:0080135	159	0.013
sensory perception	GO:0007600	245	0.013
regulation of chromatin modification	GO:1903308	57	0.013
posttranscriptional gene silencing	GO:0016441	10	0.013
regulation of multi organism process	GO:0043900	111	0.013
regulation of membrane potential	GO:0042391	192	0.013
histone mrna metabolic process	GO:0008334	3	0.013
cellular protein complex assembly	GO:0043623	116	0.012
cognition	GO:0050890	149	0.012
nucleobase containing small molecule metabolic process	GO:0055086	352	0.012
germ cell development	GO:0007281	185	0.012
somatic diversification of immunoglobulins involved in immune response	GO:0002208	36	0.012
somatic recombination of immunoglobulin gene segments	GO:0016447	42	0.012
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.012
gene silencing by rna	GO:0031047	19	0.012
cell activation involved in immune response	GO:0002263	126	0.012
response to lipopolysaccharide	GO:0032496	128	0.012
neuron death	GO:0070997	154	0.012
regulation of cell projection organization	GO:0031344	206	0.012
rna splicing via transesterification reactions	GO:0000375	43	0.012
immunoglobulin production	GO:0002377	73	0.012
cytoskeletal matrix organization at active zone	GO:0048789	1	0.012
neuron projection guidance	GO:0097485	141	0.012
endocytosis	GO:0006897	168	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.011
peptidyl lysine trimethylation	GO:0018023	12	0.011
gene silencing	GO:0016458	38	0.011
transmission of nerve impulse	GO:0019226	76	0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.011
axonogenesis	GO:0007409	274	0.011
regulation of neuron projection development	GO:0010975	169	0.011
cell cycle checkpoint	GO:0000075	47	0.011
mitotic recombination	GO:0006312	3	0.011
dendrite development	GO:0016358	115	0.011
negative regulation of cell proliferation	GO:0008285	296	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
transcription coupled nucleotide excision repair	GO:0006283	2	0.011
skin development	GO:0043588	220	0.011
organelle assembly	GO:0070925	177	0.011
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.010
negative regulation of protein metabolic process	GO:0051248	282	0.010
metal ion homeostasis	GO:0055065	189	0.010
regulation of neuron death	GO:1901214	134	0.010
maintenance of protein location in nucleus	GO:0051457	2	0.010
trna processing	GO:0008033	11	0.010	Yeast
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	51	0.010
nucleoside phosphate catabolic process	GO:1901292	222	0.010
forebrain development	GO:0030900	302	0.010
glycerolipid metabolic process	GO:0046486	122	0.010
fertilization	GO:0009566	127	0.010
regulation of chromosome organization	GO:0033044	83	0.010

Elp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.075
disease of anatomical entity	DOID:7	0.075
sensory system disease	DOID:0050155	0.031
retinal degeneration	DOID:8466	0.031
retinal disease	DOID:5679	0.031
eye disease	DOID:5614	0.031
eye and adnexa disease	DOID:1492	0.031
neuropathy	DOID:870	0.021
disease of mental health	DOID:150	0.016
central nervous system disease	DOID:331	0.012
neurodegenerative disease	DOID:1289	0.012
developmental disorder of mental health	DOID:0060037	0.010
specific developmental disorder	DOID:0060038	0.010
intellectual disability	DOID:1059	0.010

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