Mus musculus

0 known processes

Sh3gl3

SH3-domain GRB2-like 3

(Aliases: EEN-B2,Sh3d2c2,MGC118269,SH3P13,Sh3d2c)

Sh3gl3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180840.226
circadian regulation of gene expressionGO:0032922480.210
regulation of defense responseGO:00313472330.187
secretory granule organizationGO:0033363200.185
cell divisionGO:00513011200.182
regulation of cell motilityGO:20001452360.136
gliogenesisGO:00420631410.128
skin developmentGO:00435882200.126
regulation of cell migrationGO:00303342190.115
regulation of cell divisionGO:0051302760.114
inflammatory responseGO:00069542440.108
cell adhesionGO:00071553290.103
macromolecule methylationGO:00434141200.097
regulation of inflammatory responseGO:00507271470.096
cell junction organizationGO:0034330770.093
regulation of cellular amino acid metabolic processGO:000652150.091
regulation of cellular amine metabolic processGO:0033238200.089
positive regulation of apoptotic processGO:00430652170.089
Mouse
vesicle organizationGO:0016050600.083
cellular amine metabolic processGO:0044106440.082
positive regulation of protein modification processGO:00314012990.081
positive regulation of g2 m transition of mitotic cell cycleGO:001097150.081
epidermis developmentGO:00085441870.075
response to radiationGO:00093141650.074
endocytosisGO:00068971680.072
Mouse Fly
cellular amino acid metabolic processGO:00065201030.071
neuronal action potentialGO:0019228540.071
ubiquitin dependent protein catabolic processGO:00065111290.069
modification dependent macromolecule catabolic processGO:00436321330.069
positive regulation of cell cycleGO:0045787920.068
regulation of organelle organizationGO:00330432890.067
Mouse
negative regulation of molecular functionGO:00440922580.067
cellular macromolecule catabolic processGO:00442652060.065
amine metabolic processGO:0009308450.065
regulation of response to woundingGO:19030341890.065
positive regulation of cell deathGO:00109422240.064
Mouse
response to light stimulusGO:00094161350.063
locomotory behaviorGO:00076261950.062
nucleobase containing small molecule metabolic processGO:00550863520.061
regulation of cellular ketone metabolic processGO:0010565660.058
methylationGO:00322591340.058
endomembrane system organizationGO:00102561470.058
Fly
dna methylationGO:0006306430.058
cellular protein catabolic processGO:00442571550.056
modification dependent protein catabolic processGO:00199411330.055
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.055
dna alkylationGO:0006305430.055
proteolysis involved in cellular protein catabolic processGO:00516031470.054
regulation of asymmetric cell divisionGO:000978640.054
regulation of cell cycleGO:00517262810.052
transmembrane transportGO:00550854120.050
ribose phosphate metabolic processGO:00196932910.049
rac protein signal transductionGO:0016601130.048
learning or memoryGO:00076111480.047
protein catabolic processGO:00301632210.047
proteasomal protein catabolic processGO:0010498980.046
macromolecule catabolic processGO:00090572810.046
multicellular organismal signalingGO:0035637910.045
actin cytoskeleton organizationGO:00300362200.044
cell junction assemblyGO:0034329520.044
regulation of cell cycle processGO:00105641600.044
rhythmic processGO:00485111740.044
transdifferentiationGO:006029010.044
positive regulation of programmed cell deathGO:00430682180.044
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235950.043
Mouse
protein modification by small protein conjugationGO:00324461870.043
circadian rhythmGO:00076231140.043
protein modification by small protein conjugation or removalGO:00706472070.043
regulation of cell cycle g2 m phase transitionGO:1902749100.042
protein ubiquitinationGO:00165671710.042
cation transportGO:00068123990.041
protein processingGO:00164851630.041
negative regulation of protein metabolic processGO:00512482820.038
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.038
dna metabolic processGO:00062593030.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
male meiosisGO:0007140370.037
regulation of kinase activityGO:00435492490.037
regulation of membrane potentialGO:00423911920.037
regulation of circadian rhythmGO:0042752580.037
positive regulation of mitotic cell cycleGO:0045931410.036
ras protein signal transductionGO:0007265770.035
negative regulation of phosphorus metabolic processGO:00105631840.035
establishment or maintenance of cell polarityGO:0007163860.034
spermatogenesisGO:00072832840.034
regulation of apoptotic signaling pathwayGO:20012331970.033
Mouse
response to organic cyclic compoundGO:00140701980.033
rho protein signal transductionGO:0007266320.033
male gamete generationGO:00482322850.033
cytokine productionGO:00018163190.033
nucleotide metabolic processGO:00091173320.033
regulation of protein localizationGO:00328802310.033
Mouse
nitrogen compound transportGO:00717052710.032
engulfment of apoptotic cellGO:004365230.032
cell type specific apoptotic processGO:00972852680.032
protein maturationGO:00516041760.032
negative regulation of intracellular signal transductionGO:19025321670.032
body morphogenesisGO:0010171450.032
organic cyclic compound catabolic processGO:19013612950.031
mitotic cell cycle processGO:19030471590.031
apoptotic signaling pathwayGO:00971903060.031
Mouse
dna modificationGO:0006304500.031
hormone secretionGO:00468791280.030
peripheral nervous system neuron axonogenesisGO:004893630.030
regulation of mitotic cell cycleGO:00073461260.030
regulation of protein serine threonine kinase activityGO:00719001570.029
regulation of hydrolase activityGO:00513362460.029
blood vessel morphogenesisGO:00485142850.029
Zebrafish
locomotor rhythmGO:004547580.029
regulation of hormone levelsGO:00108172110.029
negative regulation of phosphate metabolic processGO:00459361840.028
organonitrogen compound biosynthetic processGO:19015661920.028
mitotic cell cycleGO:00002781950.028
regulation of cellular response to stressGO:00801351590.027
divalent inorganic cation homeostasisGO:00725071380.027
oxidation reduction processGO:00551143420.027
positive regulation of cellular amine metabolic processGO:003324050.027
ensheathment of neuronsGO:0007272760.027
wnt signaling pathwayGO:00160551880.027
negative regulation of cellular protein metabolic processGO:00322692470.026
regulation of mapk cascadeGO:00434082480.026
regulation of cell activationGO:00508652890.026
action potentialGO:0001508780.026
negative regulation of immune system processGO:00026832090.026
chemotaxisGO:00069352470.026
myeloid leukocyte differentiationGO:00025731190.026
peptidyl amino acid modificationGO:00181933360.025
g protein coupled receptor signaling pathwayGO:00071862430.025
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.025
regulation of eosinophil migrationGO:200041620.025
organelle assemblyGO:00709251770.025
anion transportGO:00068201770.025
regulation of engulfment of apoptotic cellGO:190107420.025
regulation of ion transportGO:00432692150.025
ribonucleotide metabolic processGO:00092592910.024
negative regulation of phosphorylationGO:00423261660.024
purine nucleotide metabolic processGO:00061633020.024
asymmetric stem cell divisionGO:009872230.024
cellular response to dna damage stimulusGO:00069742070.024
dna repairGO:00062811070.024
negative regulation of protein phosphorylationGO:00019331260.024
sequestering of calcium ionGO:0051208180.024
mesoderm developmentGO:00074981000.024
regulation of cytokine productionGO:00018172660.024
multicellular organism growthGO:00352641610.023
transmission of nerve impulseGO:0019226760.023
negative regulation of transferase activityGO:0051348850.023
cellular response to lipidGO:00713961450.023
organophosphate biosynthetic processGO:00904071220.023
Mouse
spermatid developmentGO:00072861080.023
meiotic cell cycleGO:00513211220.023
learningGO:0007612980.023
organelle fissionGO:00482851700.023
cellular response to organonitrogen compoundGO:00714171450.023
cation transmembrane transportGO:00986552660.022
chromatin modificationGO:00165681870.022
axon ensheathmentGO:0008366760.022
positive regulation of cell cycle processGO:0090068610.022
cell chemotaxisGO:0060326810.022
positive regulation of protein ubiquitinationGO:0031398270.022
asymmetric neuroblast divisionGO:005505910.022
positive regulation of thymocyte migrationGO:200041220.022
chromatin organizationGO:00063252060.022
cognitionGO:00508901490.022
schwann cell proliferationGO:001401020.022
axon cargo transportGO:0008088330.022
regulation of epithelial cell proliferationGO:00506781410.022
spermatid differentiationGO:00485151150.022
carbohydrate metabolic processGO:00059752300.021
fat cell differentiationGO:00454441600.021
glial cell developmentGO:0021782540.021
myelination in peripheral nervous systemGO:0022011190.021
nucleoside phosphate biosynthetic processGO:1901293790.021
response to lipopolysaccharideGO:00324961280.021
cytoplasmic transportGO:00164822340.021
negative regulation of cellular amino acid metabolic processGO:004576300.021
small gtpase mediated signal transductionGO:0007264970.021
organelle localizationGO:00516401790.021
Mouse Fly
histone modificationGO:00165701590.021
regulation of cellular catabolic processGO:00313292420.020
positive regulation of protein phosphorylationGO:00019342420.020
covalent chromatin modificationGO:00165691630.020
purine ribonucleotide metabolic processGO:00091502900.020
cellular chemical homeostasisGO:00550822150.020
carboxylic acid transportGO:00469421000.020
purine ribonucleoside metabolic processGO:00461282410.020
regulation of t cell activationGO:00508631700.020
cellular homeostasisGO:00197252400.020
regulation of neuron differentiationGO:00456642810.020
schwann cell developmentGO:0014044220.019
microtubule cytoskeleton organizationGO:00002261570.019
carbohydrate derivative biosynthetic processGO:19011371830.019
negative regulation of cellular amine metabolic processGO:003323910.019
regulation of leukocyte differentiationGO:19021051590.019
mitral valve morphogenesisGO:000318340.019
negative regulation of kinase activityGO:0033673810.019
purine containing compound metabolic processGO:00725213110.019
multi organism behaviorGO:0051705620.019
glial cell differentiationGO:00100011310.019
cellular nitrogen compound catabolic processGO:00442702800.019
embryonic organ morphogenesisGO:00485622760.018
morphogenesis of a branching structureGO:00017632030.018
monocarboxylic acid metabolic processGO:00327871910.018
myelinationGO:0042552740.018
metal ion homeostasisGO:00550651890.018
protein polymerizationGO:0051258570.018
thymocyte migrationGO:007267920.018
regulation of neuron deathGO:19012141340.018
hematopoietic progenitor cell differentiationGO:00022441430.018
myeloid leukocyte migrationGO:0097529570.018
stem cell differentiationGO:00488632680.018
receptor mediated endocytosisGO:0006898510.018
Mouse
mrna metabolic processGO:0016071840.018
eosinophil migrationGO:007267730.018
double strand break repairGO:0006302480.017
purine nucleoside metabolic processGO:00422782410.017
microtubule based processGO:00070172360.017
posttranscriptional regulation of gene expressionGO:00106081550.017
regulation of protein processingGO:0070613960.017
positive regulation of mitotic cell cycle phase transitionGO:1901992170.017
negative regulation of nervous system developmentGO:00519611560.017
regulation of protein kinase activityGO:00458592320.017
response to molecule of bacterial originGO:00022371430.017
regulation of cellular component biogenesisGO:00440871810.017
cell cycle g2 m phase transitionGO:0044839200.017
nucleotide biosynthetic processGO:0009165780.017
cyclic nucleotide biosynthetic processGO:0009190440.017
synaptic vesicle localizationGO:0097479590.017
Mouse Fly
regulation of multi organism processGO:00439001110.016
circadian behaviorGO:0048512130.016
negative regulation of protein maturationGO:1903318790.016
aromatic compound catabolic processGO:00194392860.016
oocyte constructionGO:000730820.016
positive regulation of defense responseGO:00313491240.016
purine containing compound biosynthetic processGO:0072522700.016
positive regulation of cell cycle phase transitionGO:1901989170.016
regulation of neuron apoptotic processGO:00435231220.016
negative regulation of microtubule polymerizationGO:003111520.016
regulation of protein ubiquitinationGO:0031396520.016
homeostasis of number of cellsGO:00488722100.015
leukocyte migrationGO:00509001240.015
regulation of protein maturationGO:1903317960.015
negative regulation of neuron differentiationGO:00456651010.015
male gonad developmentGO:0008584880.015
protein localization to organelleGO:00333651850.015
Mouse
peptide secretionGO:00027901140.015
myeloid cell differentiationGO:00300992330.015
compound eye developmentGO:004874910.015
rap protein signal transductionGO:003248630.015
regulation of gliogenesisGO:0014013500.015
protein deacetylationGO:0006476320.015
plasma membrane organizationGO:0007009900.015
Fly
angiogenesisGO:00015252010.015
zygotic determination of anterior posterior axis embryoGO:000735430.015
negative regulation of organelle organizationGO:0010639900.015
cation homeostasisGO:00550802120.015
regulation of cytoplasmic transportGO:19036491120.015
organonitrogen compound catabolic processGO:19015652640.015
purine nucleoside triphosphate metabolic processGO:00091442260.015
positive regulation of cytokine productionGO:00018191740.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.014
regulation of transferase activityGO:00513382630.014
maintenance of locationGO:0051235890.014
gland developmentGO:00487323300.014
synaptic transmissionGO:00072683290.014
Mouse Fly
cell fate specificationGO:0001708720.014
regulation of secretionGO:00510462740.014
neuromuscular processGO:0050905990.014
rhythmic behaviorGO:0007622150.014
g2 m transition of mitotic cell cycleGO:0000086200.014
schwann cell differentiationGO:0014037260.014
canonical wnt signaling pathwayGO:00600701300.014
positive regulation of leukocyte differentiationGO:1902107860.014
leukocyte differentiationGO:00025213420.014
organic hydroxy compound metabolic processGO:19016152030.014
macromolecule deacylationGO:0098732370.014
rna processingGO:00063961050.014
cellular calcium ion homeostasisGO:00068741190.014
peptidyl tyrosine modificationGO:00182121450.014
regulation of mitotic cell cycle phase transitionGO:1901990730.014
urogenital system developmentGO:00016552610.014
oocyte axis specificationGO:000730920.014
negative regulation of cytoskeleton organizationGO:0051494360.014
regulation of protein modification by small protein conjugation or removalGO:1903320570.014
t cell activationGO:00421102890.014
peripheral nervous system developmentGO:0007422530.014
regulation of thymocyte migrationGO:200041020.014
response to steroid hormoneGO:0048545560.013
regulation of map kinase activityGO:00434051200.013
nucleoside phosphate metabolic processGO:00067533380.013
muscle tissue developmentGO:00605373080.013
innate immune responseGO:00450871570.013
positive regulation of eosinophil migrationGO:200041820.013
response to oxidative stressGO:00069791230.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.013
germ cell developmentGO:00072811850.013
neuron neuron synaptic transmissionGO:0007270690.013
regulation of lymphocyte activationGO:00512492400.013
positive regulation of protein kinase activityGO:00458601440.013
regulation of cell adhesionGO:00301551540.013
ribonucleoside triphosphate metabolic processGO:00091992200.013
sensory organ morphogenesisGO:00905962420.013
regulation of rho protein signal transductionGO:0035023710.013
cellular component assembly involved in morphogenesisGO:00109271390.013
muscle cell differentiationGO:00426922610.013
activation of mapk activity involved in innate immune responseGO:003541920.013
mitochondrion organizationGO:00070051340.013
Mouse
regulation of cell projection organizationGO:00313442060.013
midgut developmentGO:000749440.013
cardiac ventricle developmentGO:0003231830.013
sensory perceptionGO:00076002450.013
inorganic ion transmembrane transportGO:00986602340.013
positive regulation of proteolysisGO:0045862850.013
negative regulation of protein modification processGO:00314001630.013
extracellular matrix organizationGO:00301981470.013
purine ribonucleoside catabolic processGO:00461302050.013
gonad developmentGO:00084061410.013
protein homooligomerizationGO:0051260430.012
development of primary sexual characteristicsGO:00451371430.012
striated muscle tissue developmentGO:00147062930.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
regulation of g2 m transition of mitotic cell cycleGO:0010389100.012
relaxation of muscleGO:0090075180.012
regulation of cytoskeleton organizationGO:00514931220.012
response to inorganic substanceGO:0010035960.012
negative regulation of neuron deathGO:1901215980.012
nucleoside phosphate catabolic processGO:19012922220.012
localization within membraneGO:005166840.012
microtubule based movementGO:0007018840.012
monosaccharide transportGO:0015749580.012
negative regulation of multi organism processGO:0043901680.012
negative regulation of cell activationGO:00508661110.012
neuron migrationGO:00017641220.012
positive regulation of glial cell proliferationGO:006025240.012
intrinsic apoptotic signaling pathwayGO:00971931320.012
peptidyl tyrosine phosphorylationGO:00181081430.012
cellular protein complex assemblyGO:00436231160.012
neural precursor cell proliferationGO:00613511210.012
ribose phosphate biosynthetic processGO:0046390590.012
regulation of proteolysisGO:00301621640.012
morphogenesis of a branching epitheliumGO:00611381930.012
lymphocyte differentiationGO:00300982420.012
regulation of sequence specific dna binding transcription factor activityGO:00510901060.012
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.012
negative regulation of phagocytosisGO:005076540.012
nucleocytoplasmic transportGO:00069131390.012
nuclear transportGO:00511691390.012
cellular response to acid chemicalGO:0071229680.012
carbohydrate transportGO:0008643620.012
cytosolic calcium ion homeostasisGO:0051480700.012
regulation of bindingGO:00510981110.012
regulation of fat cell differentiationGO:0045598810.012
membrane organizationGO:00610242450.012
Mouse Fly
sialylationGO:0097503140.012
calcium ion homeostasisGO:00550741270.012
monosaccharide metabolic processGO:00059961060.012
negative regulation of lymphocyte activationGO:0051250910.012
negative regulation of leukocyte differentiationGO:1902106510.012
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.011
negative regulation of integrin mediated signaling pathwayGO:200104520.011
protein targetingGO:00066051430.011
adult behaviorGO:00305341350.011
regulation of voltage gated calcium channel activityGO:190138540.011
meiotic nuclear divisionGO:00071261150.011
epithelial cell developmentGO:00020641590.011
regulation of homeostatic processGO:00328441820.011
glucose transportGO:0015758560.011
mitral valve developmentGO:000317440.011
sequestering of metal ionGO:0051238190.011
regulation of cell cycle phase transitionGO:1901987770.011
multi multicellular organism processGO:00447061090.011
mapk cascadeGO:00001652810.011
regulation of protein catabolic processGO:00421761080.011
carbohydrate biosynthetic processGO:0016051740.011
regulation of secretion by cellGO:19035302490.011
epithelial cell proliferationGO:00506731740.011
cell maturationGO:00484691270.011
regulation of peptidase activityGO:0052547960.011
hexose transportGO:0008645560.011
neuron deathGO:00709971540.011
establishment of glial blood brain barrierGO:006085720.011
mitotic cytokinesisGO:000028140.011
negative regulation of proteolysisGO:0045861740.011
blood circulationGO:00080151950.011
positive regulation of protein serine threonine kinase activityGO:00719021060.011
regulation of peptidyl tyrosine phosphorylationGO:0050730930.011
digestive tract developmentGO:00485651900.011
positive regulation of schwann cell proliferationGO:001062510.011
ion transmembrane transportGO:00342203610.011
regulation of ovulationGO:006027830.010
negative regulation of membrane potentialGO:004583740.010
response to organonitrogen compoundGO:00102432460.010
establishment or maintenance of cytoskeleton polarityGO:003095220.010
positive regulation of transferase activityGO:00513471670.010
negative regulation of protein processingGO:0010955790.010
amino acid transportGO:0006865610.010
positive regulation of mapk cascadeGO:00434101700.010
positive regulation of membrane protein ectodomain proteolysisGO:005104430.010
response to ionizing radiationGO:0010212420.010
catecholamine uptakeGO:009049340.010
extracellular structure organizationGO:00430621480.010
negative regulation of peptidase activityGO:0010466460.010
protein deacylationGO:0035601360.010
positive regulation of protein catabolic processGO:0045732600.010
regulation of synaptic growth at neuromuscular junctionGO:000858240.010
regulation of angiogenesisGO:0045765810.010
nucleoside metabolic processGO:00091162460.010
multicellular organismal homeostasisGO:00488711640.010
regulation of wnt signaling pathwayGO:00301111230.010
peptide hormone secretionGO:00300721090.010
granulocyte migrationGO:0097530430.010
regulation of stem cell divisionGO:200003540.010
positive regulation of ion transportGO:0043270650.010

Sh3gl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
central nervous system diseaseDOID:33100.015
neurodegenerative diseaseDOID:128900.015
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.013
neuropathyDOID:87000.011