Mus musculus

5 known processes

Top3b

topoisomerase (DNA) III beta

Top3b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742070.085
regulation of cellular ketone metabolic processGO:0010565660.082
dna repairGO:00062811070.073
cilium morphogenesisGO:00602711020.066
protein processingGO:00164851630.063
dna metabolic processGO:00062593030.060
cytoplasmic transportGO:00164822340.058
cilium assemblyGO:0042384810.052
cellular ketone metabolic processGO:0042180840.052
cellular amine metabolic processGO:0044106440.048
amine metabolic processGO:0009308450.048
regulation of cellular amino acid metabolic processGO:000652150.047
purine nucleoside triphosphate catabolic processGO:00091462030.043
regulation of cell cycleGO:00517262810.041
positive regulation of cellular amine metabolic processGO:003324050.039
regulation of mitotic cell cycleGO:00073461260.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
cellular amino acid metabolic processGO:00065201030.038
heterocycle catabolic processGO:00467002800.035
cellular macromolecule catabolic processGO:00442652060.034
positive regulation of apoptotic processGO:00430652170.034
regulation of organelle organizationGO:00330432890.034
protein maturationGO:00516041760.032
intracellular protein transportGO:00068862040.031
macromolecule catabolic processGO:00090572810.030
microtubule based processGO:00070172360.029
regulation of proteolysisGO:00301621640.029
cellular nitrogen compound catabolic processGO:00442702800.029
aromatic compound catabolic processGO:00194392860.028
appendage developmentGO:00487361660.028
regulation of cellular amine metabolic processGO:0033238200.028
viral gene expressionGO:001908030.027
oocyte constructionGO:000730820.026
ribonucleotide metabolic processGO:00092592910.026
positive regulation of protein phosphorylationGO:00019342420.026
nucleoside phosphate metabolic processGO:00067533380.025
organic cyclic compound catabolic processGO:19013612950.025
chromatin organizationGO:00063252060.024
cellular component assembly involved in morphogenesisGO:00109271390.024
skeletal system developmentGO:00015013560.024
positive regulation of cell deathGO:00109422240.024
nitrogen compound transportGO:00717052710.024
peptidyl amino acid modificationGO:00181933360.024
positive regulation of viral entry into host cellGO:004659830.023
immune effector processGO:00022523210.023
nuclear divisionGO:00002801580.023
carbohydrate derivative biosynthetic processGO:19011371830.023
negative regulation of cell developmentGO:00107211690.022
ras protein signal transductionGO:0007265770.022
small gtpase mediated signal transductionGO:0007264970.021
negative regulation of cellular component organizationGO:00511291940.021
regulation of apoptotic signaling pathwayGO:20012331970.021
apoptotic signaling pathwayGO:00971903060.020
mitotic cell cycleGO:00002781950.020
innate immune responseGO:00450871570.020
transmembrane transportGO:00550854120.020
protein localization to organelleGO:00333651850.020
signal transduction involved in mitotic dna damage checkpointGO:190240230.020
organelle assemblyGO:00709251770.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
regulation of cell cycle processGO:00105641600.019
negative regulation of protein metabolic processGO:00512482820.019
glycerolipid metabolic processGO:00464861220.019
positive regulation of programmed cell deathGO:00430682180.019
asymmetric neuroblast divisionGO:005505910.019
regulation of cellular component biogenesisGO:00440871810.018
nucleotide catabolic processGO:00091662170.018
positive regulation of protein modification processGO:00314012990.018
regulation of actin nucleationGO:005112540.018
regulation of hydrolase activityGO:00513362460.017
purine nucleotide catabolic processGO:00061952110.017
nucleic acid phosphodiester bond hydrolysisGO:0090305490.017
response to radiationGO:00093141650.017
synaptic transmissionGO:00072683290.017
purine ribonucleotide catabolic processGO:00091542080.017
smoothened signaling pathwayGO:00072241050.017
cell type specific apoptotic processGO:00972852680.017
mitotic cell cycle processGO:19030471590.017
chromatin modificationGO:00165681870.017
glycosyl compound metabolic processGO:19016572460.017
microtubule cytoskeleton organizationGO:00002261570.017
germ cell developmentGO:00072811850.016
asymmetric stem cell divisionGO:009872230.016
cytokine productionGO:00018163190.016
inorganic cation transmembrane transportGO:00986622070.016
purine ribonucleotide metabolic processGO:00091502900.016
spermatogenesisGO:00072832840.016
carbohydrate derivative catabolic processGO:19011362310.016
striated muscle tissue developmentGO:00147062930.016
regionalizationGO:00030023370.016
establishment of organelle localizationGO:00516561220.016
organonitrogen compound biosynthetic processGO:19015661920.016
negative regulation of dna templated transcription elongationGO:003278560.016
nucleoside triphosphate metabolic processGO:00091412300.016
organelle localizationGO:00516401790.016
response to growth factorGO:00708481980.016
regulation of protein complex assemblyGO:0043254830.016
cation transmembrane transportGO:00986552660.016
glycosyl compound catabolic processGO:19016582060.015
regulation of secretionGO:00510462740.015
organelle fissionGO:00482851700.015
spermatid developmentGO:00072861080.015
protein targetingGO:00066051430.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
maternal determination of anterior posterior axis embryoGO:000835820.015
cellular homeostasisGO:00197252400.015
appendage morphogenesisGO:00351071490.015
anatomical structure homeostasisGO:00602491450.015
ribonucleotide catabolic processGO:00092612080.015
oocyte axis specificationGO:000730920.015
muscle tissue developmentGO:00605373080.015
cation transportGO:00068123990.015
ribonucleoside triphosphate metabolic processGO:00091992200.015
organonitrogen compound catabolic processGO:19015652640.015
posttranscriptional regulation of gene expressionGO:00106081550.015
digestive system developmentGO:00551232000.015
response to molecule of bacterial originGO:00022371430.015
establishment of protein localization to organelleGO:00725941180.015
mrna metabolic processGO:0016071840.015
purine nucleoside metabolic processGO:00422782410.015
multicellular organism growthGO:00352641610.015
exocytosisGO:00068871210.015
purine nucleotide metabolic processGO:00061633020.014
negative regulation of cell proliferationGO:00082852960.014
sensory perceptionGO:00076002450.014
compound eye developmentGO:004874910.014
carbohydrate metabolic processGO:00059752300.014
telomere maintenanceGO:0000723190.014
purine ribonucleoside metabolic processGO:00461282410.014
nuclear transportGO:00511691390.014
cellular protein catabolic processGO:00442571550.014
ribonucleoside catabolic processGO:00424542060.014
purine containing compound metabolic processGO:00725213110.014
macromolecule methylationGO:00434141200.014
nucleobase containing small molecule metabolic processGO:00550863520.014
regulation of cytoskeleton organizationGO:00514931220.014
negative regulation of nlrp3 inflammasome complex assemblyGO:190022620.014
dna replicationGO:0006260520.014
cellular protein complex assemblyGO:00436231160.014
positive regulation of viral genome replicationGO:004507020.013
protein modification by small protein conjugation or removalGO:00706472070.013
nucleotide excision repairGO:0006289130.013
muscle cell differentiationGO:00426922610.013
purine containing compound catabolic processGO:00725232130.013
nucleotide metabolic processGO:00091173320.013
atp metabolic processGO:0046034750.013
inorganic ion transmembrane transportGO:00986602340.013
wnt signaling pathwayGO:00160551880.013
regulation of secretion by cellGO:19035302490.013
oocyte anterior posterior axis specificationGO:000731420.013
morphogenesis of embryonic epitheliumGO:00163311590.013
organophosphate catabolic processGO:00464342320.013
mitochondrion organizationGO:00070051340.013
regulation of cytokine productionGO:00018172660.013
positive regulation of tor signalingGO:003200830.013
positive regulation of organelle organizationGO:00106381280.013
actin filament polymerizationGO:0030041440.013
protein ubiquitinationGO:00165671710.013
glycerophospholipid metabolic processGO:0006650710.013
purine nucleoside catabolic processGO:00061522050.013
reactive oxygen species metabolic processGO:0072593840.013
modification dependent macromolecule catabolic processGO:00436321330.012
purine ribonucleoside catabolic processGO:00461302050.012
carbohydrate homeostasisGO:00335001280.012
response to organonitrogen compoundGO:00102432460.012
nucleoside monophosphate catabolic processGO:0009125590.012
acetylcholine transportGO:001587020.012
response to acid chemicalGO:00011011110.012
nucleoside triphosphate catabolic processGO:00091432050.012
skin developmentGO:00435882200.012
cellular response to biotic stimulusGO:0071216920.012
positive regulation of transferase activityGO:00513471670.012
viral transcriptionGO:001908330.012
nucleoside phosphate catabolic processGO:19012922220.012
regulation of peptide transportGO:0090087910.012
purine ribonucleoside triphosphate catabolic processGO:00092071990.012
regulation of vesicle mediated transportGO:00606271390.012
defecationGO:003042110.012
negative regulation of organelle organizationGO:0010639900.012
positive regulation of hydrolase activityGO:00513451480.012
regulation of chromosome organizationGO:0033044830.012
localization within membraneGO:005166840.012
regulation of membrane potentialGO:00423911920.012
nucleocytoplasmic transportGO:00069131390.012
sequestering of calcium ionGO:0051208180.012
cellular response to organonitrogen compoundGO:00714171450.012
regulation of cellular response to stressGO:00801351590.012
developmental maturationGO:00217001930.012
modification dependent protein catabolic processGO:00199411330.012
gland developmentGO:00487323300.012
nucleoside catabolic processGO:00091642060.012
methylationGO:00322591340.012
ribonucleoside triphosphate catabolic processGO:00092031990.011
extrinsic apoptotic signaling pathwayGO:00971911260.011
divalent inorganic cation transportGO:00725111780.011
positive regulation of proteolysisGO:0045862850.011
protein modification by small protein conjugationGO:00324461870.011
action potentialGO:0001508780.011
stem cell differentiationGO:00488632680.011
regulation of protein maturationGO:1903317960.011
regulation of smoothened signaling pathwayGO:0008589580.011
regulation of exocytosisGO:0017157610.011
regulation of protein processingGO:0070613960.011
negative regulation of viral transcriptionGO:003289730.011
regulation of mapk cascadeGO:00434082480.011
homeostasis of number of cellsGO:00488722100.011
neuron deathGO:00709971540.011
limb developmentGO:00601731660.011
cell maturationGO:00484691270.011
regulation of cell projection organizationGO:00313442060.011
lipid biosynthetic processGO:00086101790.011
ion transmembrane transportGO:00342203610.011
protein polymerizationGO:0051258570.011
response to oxygen levelsGO:0070482620.011
peptide transportGO:00158331330.011
nucleoside metabolic processGO:00091162460.011
b cell activationGO:00421131610.011
negative regulation of nervous system developmentGO:00519611560.011
purine nucleoside monophosphate metabolic processGO:0009126810.011
nucleoside monophosphate metabolic processGO:0009123850.011
interleukin 8 productionGO:003263740.011
sensory system developmentGO:004888030.010
digestive tract developmentGO:00485651900.010
forebrain developmentGO:00309003020.010
regulation of transferase activityGO:00513382630.010
embryonic organ morphogenesisGO:00485622760.010
response to lipopolysaccharideGO:00324961280.010
negative regulation of intracellular signal transductionGO:19025321670.010
cellular response to peptideGO:1901653920.010
negative regulation of cytokine productionGO:0001818840.010
rna processingGO:00063961050.010
amide transportGO:00428861380.010
stem cell maintenanceGO:00198271300.010
negative regulation of cellular protein metabolic processGO:00322692470.010
protein catabolic processGO:00301632210.010
fat cell differentiationGO:00454441600.010
double strand break repair via homologous recombinationGO:0000724210.010
sequestering of metal ionGO:0051238190.010
regulation of bindingGO:00510981110.010
leukocyte differentiationGO:00025213420.010
regulation of protein transportGO:00512231630.010
establishment or maintenance of cell polarityGO:0007163860.010
regulation of homeostatic processGO:00328441820.010
organophosphate biosynthetic processGO:00904071220.010
locomotory behaviorGO:00076261950.010
atp catabolic processGO:0006200550.010
synapsisGO:0007129340.010
actin cytoskeleton organizationGO:00300362200.010

Top3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.029
disease of anatomical entityDOID:700.029
immune system diseaseDOID:291400.024
hematopoietic system diseaseDOID:7400.024
central nervous system diseaseDOID:33100.022
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.013
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011
retinal diseaseDOID:567900.011
retinal degenerationDOID:846600.011
carbohydrate metabolic disorderDOID:297800.011
brain diseaseDOID:93600.010