IMP: Integrative Multi-species Prediction

Mus musculus

87 known processes

Slc7a2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

(Aliases: Tea,Cat2,AI158848,Atrc2)

Ensembl: ENSMUSG00000031596
Entrez: 11988
UniProtKB: P18581

Process Predictions
Disease Predictions

Slc7a2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular amino acid metabolic process	GO:0006520	103	0.809
chemotaxis	GO:0006935	247	0.792
regulation of protein kinase activity	GO:0045859	232	0.705
organic acid transport	GO:0015849	101	0.627
regulation of secretion by cell	GO:1903530	249	0.618
regulation of cellular amino acid metabolic process	GO:0006521	5	0.602
circulatory system process	GO:0003013	197	0.562
positive regulation of cellular amine metabolic process	GO:0033240	5	0.548
spermatogenesis	GO:0007283	284	0.532
regulation of secretion	GO:0051046	274	0.518
amine metabolic process	GO:0009308	45	0.515
regulation of cellular amine metabolic process	GO:0033238	20	0.511
response to organonitrogen compound	GO:0010243	246	0.497
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.494
regulation of response to wounding	GO:1903034	189	0.492
cytokine production	GO:0001816	319	0.486
immune effector process	GO:0002252	321	0.483
positive regulation of protein kinase activity	GO:0045860	144	0.481
regulation of map kinase activity	GO:0043405	120	0.473
positive regulation of transferase activity	GO:0051347	167	0.463
positive regulation of secretion by cell	GO:1903532	114	0.463
regulation of defense response	GO:0031347	233	0.459
cellular homeostasis	GO:0019725	240	0.448
regulation of transferase activity	GO:0051338	263	0.442
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.440
apoptotic signaling pathway	GO:0097190	306	0.435
cellular amine metabolic process	GO:0044106	44	0.432
inflammatory response	GO:0006954	244	0.420
cation transport	GO:0006812	399	0.415
positive regulation of protein phosphorylation	GO:0001934	242	0.414
regulation of body fluid levels	GO:0050878	162	0.411
regulation of hormone levels	GO:0010817	211	0.409
blood coagulation	GO:0007596	76	0.402
regulation of cell adhesion	GO:0030155	154	0.402
regulation of anatomical structure size	GO:0090066	178	0.399
regulation of protein serine threonine kinase activity	GO:0071900	157	0.399
regulation of kinase activity	GO:0043549	249	0.395
hemostasis	GO:0007599	78	0.388
cation homeostasis	GO:0055080	212	0.377
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.377
regulation of cell activation	GO:0050865	289	0.376
tissue remodeling	GO:0048771	102	0.375
oxidation reduction process	GO:0055114	342	0.372
peptidyl amino acid modification	GO:0018193	336	0.366
blood vessel morphogenesis	GO:0048514	285	0.358
rhythmic process	GO:0048511	174	0.355
adult behavior	GO:0030534	135	0.346
cellular ketone metabolic process	GO:0042180	84	0.327
regulation of protein transport	GO:0051223	163	0.326
hindbrain development	GO:0030902	128	0.325
regulation of mapk cascade	GO:0043408	248	0.324
organic hydroxy compound metabolic process	GO:1901615	203	0.322
positive regulation of cell development	GO:0010720	237	0.319
positive regulation of protein modification process	GO:0031401	299	0.317
cell adhesion	GO:0007155	329	0.314
regulation of cell migration	GO:0030334	219	0.313
negative regulation of cell proliferation	GO:0008285	296	0.312
neuron migration	GO:0001764	122	0.312
regulation of cytokine production	GO:0001817	266	0.307
regulation of system process	GO:0044057	200	0.306
hormone secretion	GO:0046879	128	0.306
blood circulation	GO:0008015	195	0.305
positive regulation of map kinase activity	GO:0043406	84	0.304
axon guidance	GO:0007411	141	0.298
vascular process in circulatory system	GO:0003018	62	0.295
regulation of establishment of protein localization	GO:0070201	181	0.276
t cell activation	GO:0042110	289	0.276
cell substrate adhesion	GO:0031589	130	0.268
hexose metabolic process	GO:0019318	98	0.265
positive regulation of cell activation	GO:0050867	158	0.265
forebrain development	GO:0030900	302	0.262
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.261
regulation of cellular ketone metabolic process	GO:0010565	66	0.260
wound healing	GO:0042060	157	0.260
female sex differentiation	GO:0046660	84	0.257
platelet activation	GO:0030168	40	0.250
alcohol metabolic process	GO:0006066	116	0.247
cell fate commitment	GO:0045165	210	0.245
positive regulation of cytokine production	GO:0001819	174	0.244
small molecule biosynthetic process	GO:0044283	132	0.241
innate immune response	GO:0045087	157	0.240
gland development	GO:0048732	330	0.240
generation of precursor metabolites and energy	GO:0006091	103	0.238
regulation of cell growth	GO:0001558	91	0.232
response to peptide hormone	GO:0043434	127	0.231
negative regulation of defense response	GO:0031348	77	0.231
regulation of chemotaxis	GO:0050920	53	0.229
positive regulation of cell migration	GO:0030335	109	0.228
positive regulation of mapk cascade	GO:0043410	170	0.228
male gamete generation	GO:0048232	285	0.227
regulation of cell motility	GO:2000145	236	0.226
carbohydrate metabolic process	GO:0005975	230	0.224
leukocyte proliferation	GO:0070661	172	0.224
negative regulation of growth	GO:0045926	99	0.223
germ cell development	GO:0007281	185	0.222
connective tissue development	GO:0061448	179	0.220
angiogenesis	GO:0001525	201	0.220
cellular response to organonitrogen compound	GO:0071417	145	0.218
lymphocyte proliferation	GO:0046651	164	0.213
mapk cascade	GO:0000165	281	0.212
positive regulation of kinase activity	GO:0033674	155	0.211
regulation of hormone secretion	GO:0046883	88	0.207
positive regulation of secretion	GO:0051047	130	0.206
cellular chemical homeostasis	GO:0055082	215	0.205
epithelial cell proliferation	GO:0050673	174	0.205
leukocyte migration	GO:0050900	124	0.203
positive regulation of apoptotic process	GO:0043065	217	0.201
skeletal system development	GO:0001501	356	0.201
regulation of inflammatory response	GO:0050727	147	0.201
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.198
telencephalon development	GO:0021537	186	0.197
regulation of epithelial cell proliferation	GO:0050678	141	0.196
nitrogen compound transport	GO:0071705	271	0.193
negative regulation of molecular function	GO:0044092	258	0.191
cell type specific apoptotic process	GO:0097285	268	0.190
regulation of systemic arterial blood pressure	GO:0003073	61	0.187
positive regulation of blood pressure	GO:0045777	21	0.186
anion transport	GO:0006820	177	0.183
peptide secretion	GO:0002790	114	0.181
regulation of tube size	GO:0035150	57	0.180
pallium development	GO:0021543	120	0.180
lipid transport	GO:0006869	98	0.179
insulin secretion	GO:0030073	89	0.178
fat soluble vitamin biosynthetic process	GO:0042362	4	0.178
gliogenesis	GO:0042063	141	0.178
appendage morphogenesis	GO:0035107	149	0.178
positive regulation of programmed cell death	GO:0043068	218	0.177
regulation of blood vessel size	GO:0050880	56	0.177
neuron death	GO:0070997	154	0.174
fat cell differentiation	GO:0045444	160	0.172
reactive nitrogen species metabolic process	GO:2001057	0	0.172
renal system development	GO:0072001	225	0.171
skin development	GO:0043588	220	0.170
metal ion homeostasis	GO:0055065	189	0.170
regulation of blood pressure	GO:0008217	93	0.169
coagulation	GO:0050817	78	0.169
regulation of apoptotic signaling pathway	GO:2001233	197	0.169
regulation of neuron death	GO:1901214	134	0.167
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.167
cellular metal ion homeostasis	GO:0006875	151	0.167
cellular lipid metabolic process	GO:0044255	323	0.165
sulfur compound metabolic process	GO:0006790	100	0.165
response to organic cyclic compound	GO:0014070	198	0.164
posttranscriptional regulation of gene expression	GO:0010608	155	0.163
monocarboxylic acid metabolic process	GO:0032787	191	0.157
kidney development	GO:0001822	213	0.155
developmental cell growth	GO:0048588	84	0.155
positive regulation of leukocyte proliferation	GO:0070665	73	0.154
cytoplasmic transport	GO:0016482	234	0.154
response to oxidative stress	GO:0006979	123	0.154
development of primary sexual characteristics	GO:0045137	143	0.153
g protein coupled receptor signaling pathway	GO:0007186	243	0.152
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.147
central nervous system neuron differentiation	GO:0021953	162	0.146
cellular modified amino acid metabolic process	GO:0006575	63	0.146
negative regulation of neuron death	GO:1901215	98	0.144
calcium ion homeostasis	GO:0055074	127	0.144
single organism nuclear import	GO:1902593	95	0.142
kidney epithelium development	GO:0072073	121	0.141
placenta development	GO:0001890	140	0.141
regulation of ion transport	GO:0043269	215	0.140
leukocyte differentiation	GO:0002521	342	0.139
reactive oxygen species biosynthetic process	GO:1903409	8	0.137
energy derivation by oxidation of organic compounds	GO:0015980	77	0.137
extrinsic apoptotic signaling pathway	GO:0097191	126	0.135
response to extracellular stimulus	GO:0009991	127	0.135
muscle tissue development	GO:0060537	308	0.135
central nervous system neuron development	GO:0021954	67	0.133
activation of mapk activity	GO:0000187	59	0.132
positive regulation of lymphocyte activation	GO:0051251	140	0.132
positive regulation of cell death	GO:0010942	224	0.132
skeletal system morphogenesis	GO:0048705	203	0.132
tissue migration	GO:0090130	68	0.131
muscle cell differentiation	GO:0042692	261	0.130
positive regulation of growth	GO:0045927	104	0.130
response to lipopolysaccharide	GO:0032496	128	0.129
urogenital system development	GO:0001655	261	0.128
cellular response to biotic stimulus	GO:0071216	92	0.126
intracellular protein transport	GO:0006886	204	0.126
lipid biosynthetic process	GO:0008610	179	0.125
extracellular structure organization	GO:0043062	148	0.125
response to peptide	GO:1901652	136	0.125
mesonephros development	GO:0001823	97	0.124
negative regulation of synapse assembly	GO:0051964	3	0.124
appendage development	GO:0048736	166	0.123
regulation of homeostatic process	GO:0032844	182	0.122
cellular response to growth factor stimulus	GO:0071363	197	0.122
ear development	GO:0043583	200	0.121
mesenchyme development	GO:0060485	152	0.120
regionalization	GO:0003002	337	0.120
epithelial tube morphogenesis	GO:0060562	303	0.120
positive regulation of lymphocyte proliferation	GO:0050671	70	0.120
regulation of proteolysis	GO:0030162	164	0.120
cell matrix adhesion	GO:0007160	68	0.120
cellular response to cytokine stimulus	GO:0071345	189	0.119
ossification	GO:0001503	216	0.119
morphogenesis of a branching structure	GO:0001763	203	0.119
morphogenesis of a branching epithelium	GO:0061138	193	0.118
embryonic appendage morphogenesis	GO:0035113	126	0.118
negative regulation of response to wounding	GO:1903035	77	0.117
organic hydroxy compound biosynthetic process	GO:1901617	77	0.117
leukocyte apoptotic process	GO:0071887	71	0.117
transmembrane transport	GO:0055085	412	0.117
cell growth	GO:0016049	130	0.115
carbohydrate biosynthetic process	GO:0016051	74	0.115
cell chemotaxis	GO:0060326	81	0.114
positive regulation of insulin receptor signaling pathway	GO:0046628	4	0.114
detection of stimulus	GO:0051606	84	0.113
l amino acid transport	GO:0015807	32	0.112
glial cell differentiation	GO:0010001	131	0.112
calcium mediated signaling	GO:0019722	46	0.112
regulation of peptidase activity	GO:0052547	96	0.111
regulation of protein localization	GO:0032880	231	0.110
t cell proliferation	GO:0042098	120	0.110
camera type eye development	GO:0043010	266	0.110
multi multicellular organism process	GO:0044706	109	0.110
negative regulation of neuron apoptotic process	GO:0043524	92	0.109
negative regulation of protein metabolic process	GO:0051248	282	0.109
membrane organization	GO:0061024	245	0.108
hexose biosynthetic process	GO:0019319	39	0.108
positive regulation of nervous system development	GO:0051962	221	0.107
cellular carbohydrate metabolic process	GO:0044262	119	0.105
sensory perception	GO:0007600	245	0.105
smooth muscle contraction	GO:0006939	44	0.105
ameboidal type cell migration	GO:0001667	128	0.104
nucleocytoplasmic transport	GO:0006913	139	0.103
response to monosaccharide	GO:0034284	67	0.103
inner ear morphogenesis	GO:0042472	101	0.103
regulation of cellular catabolic process	GO:0031329	242	0.102
cellular ion homeostasis	GO:0006873	165	0.102
regulation of lymphocyte proliferation	GO:0050670	117	0.101
glycoprotein metabolic process	GO:0009100	116	0.101
cellular calcium ion homeostasis	GO:0006874	119	0.100
macromolecule catabolic process	GO:0009057	281	0.100
lipid localization	GO:0010876	126	0.099
positive regulation of cell growth	GO:0030307	33	0.099
hormone metabolic process	GO:0042445	86	0.099
carbohydrate homeostasis	GO:0033500	128	0.099
regulation of vesicle mediated transport	GO:0060627	139	0.099
response to radiation	GO:0009314	165	0.099
phosphatidylinositol mediated signaling	GO:0048015	41	0.099
epithelial cell migration	GO:0010631	63	0.098
mesonephric tubule development	GO:0072164	94	0.097
response to amphetamine	GO:0001975	16	0.097
regulation of cell size	GO:0008361	72	0.097
response to inorganic substance	GO:0010035	96	0.097
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.097
cellular response to molecule of bacterial origin	GO:0071219	83	0.096
exocytosis	GO:0006887	121	0.096
organic hydroxy compound transport	GO:0015850	93	0.096
negative regulation of nervous system development	GO:0051961	156	0.095
alpha amino acid metabolic process	GO:1901605	59	0.095
retina development in camera type eye	GO:0060041	119	0.094
nucleobase containing small molecule metabolic process	GO:0055086	352	0.094
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.093
amino acid transport	GO:0006865	61	0.093
immune response regulating signaling pathway	GO:0002764	125	0.092
t cell differentiation in thymus	GO:0033077	77	0.092
protein kinase b signaling	GO:0043491	74	0.092
cartilage development	GO:0051216	140	0.092
ureteric bud development	GO:0001657	94	0.090
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.090
metencephalon development	GO:0022037	89	0.090
rho protein signal transduction	GO:0007266	32	0.090
limb morphogenesis	GO:0035108	149	0.090
glucose homeostasis	GO:0042593	128	0.090
steroid metabolic process	GO:0008202	119	0.089
regulation of carbohydrate metabolic process	GO:0006109	75	0.089
associative learning	GO:0008306	61	0.089
regulation of intracellular transport	GO:0032386	159	0.089
transforming growth factor beta receptor signaling pathway	GO:0007179	71	0.089
protein localization to nucleus	GO:0034504	121	0.088
regulation of ossification	GO:0030278	112	0.087
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.086
response to oxygen levels	GO:0070482	62	0.086
respiratory system development	GO:0060541	190	0.086
response to molecule of bacterial origin	GO:0002237	143	0.085
carbohydrate derivative biosynthetic process	GO:1901137	183	0.085
extracellular matrix organization	GO:0030198	147	0.085
regulation of membrane potential	GO:0042391	192	0.084
regulation of phosphatidylinositol 3 kinase signaling	GO:0014066	30	0.084
nucleotide metabolic process	GO:0009117	332	0.083
protein modification by small protein conjugation or removal	GO:0070647	207	0.083
bone mineralization	GO:0030282	54	0.083
response to growth factor	GO:0070848	198	0.082
regulation of lipid metabolic process	GO:0019216	118	0.082
circadian regulation of gene expression	GO:0032922	48	0.082
regulation of stem cell differentiation	GO:2000736	50	0.082
cellular response to lipid	GO:0071396	145	0.082
myeloid cell differentiation	GO:0030099	233	0.082
branching morphogenesis of an epithelial tube	GO:0048754	159	0.081
positive regulation of cell motility	GO:2000147	116	0.080
amide transport	GO:0042886	138	0.080
mesonephric epithelium development	GO:0072163	94	0.079
regulation of wound healing	GO:0061041	40	0.079
cellular response to extracellular stimulus	GO:0031668	81	0.078
protein modification by small protein conjugation	GO:0032446	187	0.078
muscle system process	GO:0003012	141	0.078
regulation of protein secretion	GO:0050708	82	0.078
developmental maturation	GO:0021700	193	0.078
vascular endothelial growth factor production	GO:0010573	13	0.077
ras protein signal transduction	GO:0007265	77	0.077
positive regulation of adaptive immune response	GO:0002821	61	0.076
regulation of tissue remodeling	GO:0034103	38	0.076
multicellular organismal homeostasis	GO:0048871	164	0.075
anatomical structure homeostasis	GO:0060249	145	0.075
nuclear transport	GO:0051169	139	0.074
cellular response to cadmium ion	GO:0071276	3	0.074
monosaccharide biosynthetic process	GO:0046364	44	0.074
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.074
cellular response to insulin stimulus	GO:0032869	78	0.073
cellular response to lipopolysaccharide	GO:0071222	77	0.073
regulation of steroid metabolic process	GO:0019218	39	0.073
negative regulation of intracellular signal transduction	GO:1902532	167	0.073
glucose metabolic process	GO:0006006	92	0.072
transmission of nerve impulse	GO:0019226	76	0.072
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.072
respiratory tube development	GO:0030323	167	0.072
synapse assembly	GO:0007416	56	0.072
regulation of cell cycle	GO:0051726	281	0.071
ion transmembrane transport	GO:0034220	361	0.071
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.071
positive regulation of neuron projection development	GO:0010976	79	0.071
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.071
organic anion transport	GO:0015711	137	0.071
negative regulation of cellular protein metabolic process	GO:0032269	247	0.070
protein catabolic process	GO:0030163	221	0.070
phasic smooth muscle contraction	GO:0014821	8	0.070
activation of immune response	GO:0002253	138	0.070
regulation of peptide hormone secretion	GO:0090276	75	0.070
peptidyl serine phosphorylation	GO:0018105	74	0.070
single organism cell adhesion	GO:0098602	156	0.070
regulation of vasculature development	GO:1901342	88	0.069
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.069
regulation of erk1 and erk2 cascade	GO:0070372	71	0.069
axon ensheathment	GO:0008366	76	0.068
forebrain neuron differentiation	GO:0021879	52	0.068
bone resorption	GO:0045453	38	0.068
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.068
regulation of peptide transport	GO:0090087	91	0.067
eye photoreceptor cell differentiation	GO:0001754	41	0.067
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.067
alanine transport	GO:0032328	4	0.067
regulation of postsynaptic membrane potential	GO:0060078	48	0.067
regulation of lymphocyte activation	GO:0051249	240	0.067
positive regulation of heart rate by epinephrine norepinephrine	GO:0001996	4	0.067
multicellular organismal signaling	GO:0035637	91	0.067
positive regulation of neuron differentiation	GO:0045666	141	0.066
lymphocyte apoptotic process	GO:0070227	54	0.066
collagen fibril organization	GO:0030199	32	0.066
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.066
regulation of leukocyte proliferation	GO:0070663	121	0.066
myotube differentiation	GO:0014902	105	0.066
positive regulation of phosphatidylinositol 3 kinase signaling	GO:0014068	20	0.065
regulation of neuron apoptotic process	GO:0043523	122	0.065
regulation of endopeptidase activity	GO:0052548	89	0.065
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002824	61	0.065
fatty acid metabolic process	GO:0006631	121	0.065
regulation of glucose metabolic process	GO:0010906	60	0.064
regulation of leukocyte mediated immunity	GO:0002703	104	0.064
negative regulation of secretion	GO:0051048	61	0.064
circadian rhythm	GO:0007623	114	0.064
membrane depolarization	GO:0051899	64	0.064
defense response to other organism	GO:0098542	197	0.064
heterocycle catabolic process	GO:0046700	280	0.064
monosaccharide metabolic process	GO:0005996	106	0.064
negative regulation of phosphorus metabolic process	GO:0010563	184	0.063
organ regeneration	GO:0031100	2	0.063
carbohydrate derivative catabolic process	GO:1901136	231	0.063
biomineral tissue development	GO:0031214	64	0.063
regulation of axon extension	GO:0030516	43	0.062
cell recognition	GO:0008037	83	0.062
lymphocyte differentiation	GO:0030098	242	0.062
reactive oxygen species metabolic process	GO:0072593	84	0.062
bone remodeling	GO:0046849	53	0.062
negative regulation of bmp signaling pathway	GO:0030514	35	0.062
oocyte differentiation	GO:0009994	35	0.062
regulation of organ morphogenesis	GO:2000027	144	0.061
glycoprotein biosynthetic process	GO:0009101	89	0.061
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.061
regulation of stress activated mapk cascade	GO:0032872	69	0.061
purine containing compound metabolic process	GO:0072521	311	0.061
renal system process	GO:0003014	48	0.061
developmental growth involved in morphogenesis	GO:0060560	138	0.060
female gonad development	GO:0008585	71	0.060
purine nucleotide metabolic process	GO:0006163	302	0.060
regulation of cellular response to stress	GO:0080135	159	0.060
learning or memory	GO:0007611	148	0.060
somite development	GO:0061053	81	0.060
negative regulation of neuron projection development	GO:0010977	50	0.060
embryonic placenta development	GO:0001892	98	0.060
carboxylic acid transport	GO:0046942	100	0.060
neuron projection guidance	GO:0097485	141	0.059
endocrine process	GO:0050886	39	0.059
positive regulation of fat cell differentiation	GO:0045600	32	0.059
epithelial cell development	GO:0002064	159	0.059
peptidyl tyrosine modification	GO:0018212	145	0.059
multicellular organism growth	GO:0035264	161	0.059
positive regulation of t cell activation	GO:0050870	101	0.059
positive regulation of epithelial cell proliferation	GO:0050679	68	0.059
purine containing compound catabolic process	GO:0072523	213	0.058
coenzyme metabolic process	GO:0006732	52	0.058
regulation of neuron differentiation	GO:0045664	281	0.058
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.058
mesenchymal cell differentiation	GO:0048762	107	0.057
cellular response to carbohydrate stimulus	GO:0071322	50	0.057
regulation of bmp signaling pathway	GO:0030510	60	0.056
ensheathment of neurons	GO:0007272	76	0.056
regulation of peptide secretion	GO:0002791	77	0.056
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.056
organonitrogen compound catabolic process	GO:1901565	264	0.056
epithelium migration	GO:0090132	63	0.056
mesenchymal cell development	GO:0014031	93	0.056
positive regulation of chemotaxis	GO:0050921	38	0.056
cognition	GO:0050890	149	0.056
cellular response to external stimulus	GO:0071496	88	0.056
lipid catabolic process	GO:0016042	69	0.055
regulation of fat cell differentiation	GO:0045598	81	0.055
negative regulation of inflammatory response	GO:0050728	61	0.055
muscle cell proliferation	GO:0033002	52	0.055
positive regulation of cellular catabolic process	GO:0031331	148	0.055
negative regulation of phosphorylation	GO:0042326	166	0.055
maintenance of location	GO:0051235	89	0.055
neuronal action potential	GO:0019228	54	0.055
cellular response to glucose stimulus	GO:0071333	45	0.055
cofactor transport	GO:0051181	4	0.055
myeloid leukocyte activation	GO:0002274	83	0.054
neuron apoptotic process	GO:0051402	142	0.054
purine nucleotide catabolic process	GO:0006195	211	0.054
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.054
negative regulation of endopeptidase activity	GO:0010951	44	0.054
cellular response to peptide hormone stimulus	GO:0071375	92	0.053
positive regulation of glycolytic process	GO:0045821	4	0.053
primary neural tube formation	GO:0014020	95	0.053
response to acid chemical	GO:0001101	111	0.053
negative regulation of phosphate metabolic process	GO:0045936	184	0.052
cytosolic calcium ion homeostasis	GO:0051480	70	0.052
immune response activating signal transduction	GO:0002757	116	0.052
regeneration	GO:0031099	38	0.051
cellular response to hormone stimulus	GO:0032870	150	0.051
lung development	GO:0030324	164	0.051
response to alcohol	GO:0097305	48	0.051
regulation of cellular component biogenesis	GO:0044087	181	0.051
positive regulation of protein kinase b signaling	GO:0051897	32	0.050
regulation of exocytosis	GO:0017157	61	0.050
regulation of stem cell proliferation	GO:0072091	78	0.050
inositol lipid mediated signaling	GO:0048017	41	0.050
regulation of ras protein signal transduction	GO:0046578	114	0.050
regulation of angiogenesis	GO:0045765	81	0.050
regulation of axon guidance	GO:1902667	13	0.050
spermatid differentiation	GO:0048515	115	0.050
synapse organization	GO:0050808	125	0.050
cellular response to monosaccharide stimulus	GO:0071326	47	0.050
organic cyclic compound catabolic process	GO:1901361	295	0.050
protein processing	GO:0016485	163	0.050
glial cell development	GO:0021782	54	0.050
organic acid biosynthetic process	GO:0016053	86	0.049
cellular glucose homeostasis	GO:0001678	52	0.049
cell maturation	GO:0048469	127	0.049
monoamine transport	GO:0015844	33	0.049
cellular amino acid catabolic process	GO:0009063	25	0.049
regulation of protein maturation	GO:1903317	96	0.049
homeostasis of number of cells	GO:0048872	210	0.049
organ growth	GO:0035265	117	0.048
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.048
negative regulation of cellular component organization	GO:0051129	194	0.048
ureteric bud morphogenesis	GO:0060675	62	0.048
peptide transport	GO:0015833	133	0.048
protein maturation	GO:0051604	176	0.048
nephron tubule morphogenesis	GO:0072078	68	0.047
protein targeting	GO:0006605	143	0.047
regulation of lymphocyte mediated immunity	GO:0002706	84	0.047
stem cell differentiation	GO:0048863	268	0.047
regulation of vascular endothelial growth factor production	GO:0010574	13	0.047
negative regulation of axon guidance	GO:1902668	8	0.047
glycogen metabolic process	GO:0005977	32	0.047
regulation of metal ion transport	GO:0010959	106	0.047
striated muscle tissue development	GO:0014706	293	0.047
ribose phosphate metabolic process	GO:0019693	291	0.047
peptide hormone secretion	GO:0030072	109	0.047
defense response to bacterium	GO:0042742	119	0.046
smoothened signaling pathway	GO:0007224	105	0.046
positive regulation of hormone secretion	GO:0046887	38	0.046
learning	GO:0007612	98	0.046
immune response regulating cell surface receptor signaling pathway	GO:0002768	80	0.046
negative regulation of protein processing	GO:0010955	79	0.046
vitamin d biosynthetic process	GO:0042368	3	0.046
epidermis development	GO:0008544	187	0.046
negative regulation of homeostatic process	GO:0032845	71	0.046
cerebellum development	GO:0021549	77	0.046
response to steroid hormone	GO:0048545	56	0.046
retinal blood vessel morphogenesis	GO:0061304	3	0.046
purine ribonucleotide catabolic process	GO:0009154	208	0.046
peptidyl tyrosine phosphorylation	GO:0018108	143	0.046
response to hypoxia	GO:0001666	58	0.045
divalent inorganic cation homeostasis	GO:0072507	138	0.045
g protein coupled receptor internalization	GO:0002031	3	0.045

Slc7a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of metabolism	DOID:0014667	0	0.222
	inherited metabolic disorder	DOID:655	0	0.140

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