Mus musculus

0 known processes

Smap2

stromal membrane-associated GTPase-activating protein 2

(Aliases: 1810031K02Rik,Smap1l,AA408614)

Smap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238200.197
purine ribonucleotide metabolic processGO:00091502900.183
Yeast Mouse
cellular amine metabolic processGO:0044106440.172
regulation of cellular amino acid metabolic processGO:000652150.158
cellular amino acid metabolic processGO:00065201030.157
amine metabolic processGO:0009308450.140
peptidyl amino acid modificationGO:00181933360.134
organonitrogen compound catabolic processGO:19015652640.129
Yeast Mouse
nucleobase containing small molecule metabolic processGO:00550863520.111
Yeast Mouse
cellular ketone metabolic processGO:0042180840.108
protein modification by small protein conjugation or removalGO:00706472070.098
actin cytoskeleton organizationGO:00300362200.094
glycosyl compound metabolic processGO:19016572460.092
Yeast Mouse
protein modification by small protein conjugationGO:00324461870.092
nucleoside phosphate metabolic processGO:00067533380.091
Yeast Mouse
negative regulation of cellular amine metabolic processGO:003323910.086
ras protein signal transductionGO:0007265770.085
ribonucleotide catabolic processGO:00092612080.082
Yeast Mouse
small gtpase mediated signal transductionGO:0007264970.081
regulation of cellular ketone metabolic processGO:0010565660.080
negative regulation of transferase activityGO:0051348850.072
nucleoside metabolic processGO:00091162460.071
Yeast Mouse
myeloid cell differentiationGO:00300992330.068
Mouse
protein ubiquitinationGO:00165671710.066
purine nucleotide metabolic processGO:00061633020.066
Yeast Mouse
glycosyl compound catabolic processGO:19016582060.065
Yeast Mouse
peptidyl tyrosine phosphorylationGO:00181081430.064
negative regulation of protein phosphorylationGO:00019331260.063
negative regulation of kinase activityGO:0033673810.063
cellular nitrogen compound catabolic processGO:00442702800.062
Yeast Mouse
cellular protein complex assemblyGO:00436231160.062
cell adhesionGO:00071553290.062
histone modificationGO:00165701590.061
positive regulation of cellular amino acid metabolic processGO:004576430.060
cellular lipid metabolic processGO:00442553230.060
nucleoside catabolic processGO:00091642060.059
Yeast Mouse
regulation of ras gtpase activityGO:0032318880.057
cytoplasmic transportGO:00164822340.057
Yeast
purine ribonucleoside catabolic processGO:00461302050.057
Yeast Mouse
organic cyclic compound catabolic processGO:19013612950.057
Yeast Mouse
regulation of homeostatic processGO:00328441820.056
Mouse
protein processingGO:00164851630.054
actin filament organizationGO:00070151130.054
regulation of organelle organizationGO:00330432890.052
heterocycle catabolic processGO:00467002800.051
Yeast Mouse
axonogenesisGO:00074092740.051
gtp catabolic processGO:00061841430.050
Yeast Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.050
regulation of hydrolase activityGO:00513362460.049
Yeast Mouse
negative regulation of molecular functionGO:00440922580.049
ribonucleoside metabolic processGO:00091192450.049
Yeast Mouse
regulation of purine nucleotide metabolic processGO:19005421690.046
Yeast Mouse
regulation of gtp catabolic processGO:00331241130.046
Yeast Mouse
regulation of protein kinase activityGO:00458592320.046
protein catabolic processGO:00301632210.046
organelle assemblyGO:00709251770.046
ubiquitin dependent protein catabolic processGO:00065111290.045
apoptotic signaling pathwayGO:00971903060.045
purine ribonucleoside triphosphate catabolic processGO:00092071990.044
Yeast Mouse
ribonucleoside triphosphate metabolic processGO:00091992200.043
Yeast Mouse
cellular response to cytokine stimulusGO:00713451890.043
protein localization to membraneGO:00726571080.042
negative regulation of cellular protein metabolic processGO:00322692470.042
membrane organizationGO:00610242450.042
regulation of transferase activityGO:00513382630.042
positive regulation of hydrolase activityGO:00513451480.042
Yeast Mouse
ion transmembrane transportGO:00342203610.041
regulation of apoptotic signaling pathwayGO:20012331970.040
regulation of intracellular transportGO:00323861590.040
cation transportGO:00068123990.040
dephosphorylationGO:00163111290.040
sequestering of metal ionGO:0051238190.040
ribonucleoside catabolic processGO:00424542060.040
Yeast Mouse
gland developmentGO:00487323300.040
regulation of vesicle mediated transportGO:00606271390.039
Mouse
chromatin modificationGO:00165681870.038
guanosine containing compound metabolic processGO:19010681440.038
Yeast Mouse
protein localization to plasma membraneGO:0072659570.038
macromolecule catabolic processGO:00090572810.038
transmembrane transportGO:00550854120.037
positive regulation of cellular amine metabolic processGO:003324050.037
negative regulation of protein serine threonine kinase activityGO:0071901490.036
purine nucleoside catabolic processGO:00061522050.036
Yeast Mouse
nucleotide metabolic processGO:00091173320.036
Yeast Mouse
endomembrane system organizationGO:00102561470.035
protein maturationGO:00516041760.035
regulation of proteolysisGO:00301621640.034
activation of immune responseGO:00022531380.034
immune effector processGO:00022523210.034
modification dependent macromolecule catabolic processGO:00436321330.034
organophosphate catabolic processGO:00464342320.034
Yeast Mouse
nitrogen compound transportGO:00717052710.033
regulation of map kinase activityGO:00434051200.033
purine nucleoside triphosphate metabolic processGO:00091442260.033
Yeast Mouse
nucleoside triphosphate catabolic processGO:00091432050.032
Yeast Mouse
negative regulation of phosphorus metabolic processGO:00105631840.032
carbohydrate derivative catabolic processGO:19011362310.032
Yeast Mouse
hematopoietic progenitor cell differentiationGO:00022441430.031
proteolysis involved in cellular protein catabolic processGO:00516031470.031
immune response regulating signaling pathwayGO:00027641250.031
endocytosisGO:00068971680.031
Mouse
modification dependent protein catabolic processGO:00199411330.031
regulation of protein serine threonine kinase activityGO:00719001570.031
positive regulation of protein phosphorylationGO:00019342420.030
regulation of kinase activityGO:00435492490.029
regulation of actin polymerization or depolymerizationGO:0008064450.029
purine nucleoside metabolic processGO:00422782410.029
Yeast Mouse
organelle fissionGO:00482851700.029
inorganic ion transmembrane transportGO:00986602340.029
regulation of response to woundingGO:19030341890.029
negative regulation of cellular component organizationGO:00511291940.029
regulation of endopeptidase activityGO:0052548890.029
inorganic cation transmembrane transportGO:00986622070.028
actin polymerization or depolymerizationGO:0008154540.028
lipid modificationGO:0030258650.028
negative regulation of protein modification processGO:00314001630.028
regulation of inflammatory responseGO:00507271470.027
peptidyl tyrosine modificationGO:00182121450.027
regulation of protein localizationGO:00328802310.027
innate immune responseGO:00450871570.027
ribose phosphate metabolic processGO:00196932910.027
Yeast Mouse
covalent chromatin modificationGO:00165691630.027
negative regulation of protein metabolic processGO:00512482820.027
cellular response to organonitrogen compoundGO:00714171450.027
cation transmembrane transportGO:00986552660.026
actin filament polymerizationGO:0030041440.026
cell type specific apoptotic processGO:00972852680.026
cation homeostasisGO:00550802120.026
vesicle organizationGO:0016050600.026
cellular ion homeostasisGO:00068731650.026
cell chemotaxisGO:0060326810.025
leukocyte differentiationGO:00025213420.025
regulation of cell activationGO:00508652890.025
golgi vesicle transportGO:0048193300.025
Yeast
regulation of bindingGO:00510981110.025
regulation of purine nucleotide catabolic processGO:00331211220.025
Yeast Mouse
protein localization to organelleGO:00333651850.025
cellular macromolecule catabolic processGO:00442652060.025
positive regulation of programmed cell deathGO:00430682180.025
skin developmentGO:00435882200.025
intracellular protein transportGO:00068862040.024
post embryonic retina morphogenesis in camera type eyeGO:006006030.024
plasma membrane organizationGO:0007009900.024
response to organonitrogen compoundGO:00102432460.024
positive regulation of growthGO:00459271040.024
immune response activating signal transductionGO:00027571160.023
positive regulation of protein modification processGO:00314012990.023
male gamete generationGO:00482322850.023
response to lipopolysaccharideGO:00324961280.023
cytokine mediated signaling pathwayGO:00192211150.023
regulation of peptidyl tyrosine phosphorylationGO:0050730930.023
chemotaxisGO:00069352470.023
mapk cascadeGO:00001652810.023
positive regulation of mapk cascadeGO:00434101700.023
organelle localizationGO:00516401790.023
microtubule based processGO:00070172360.023
response to growth factorGO:00708481980.023
regulation of endocytosisGO:0030100690.022
Mouse
regulation of nucleotide metabolic processGO:00061401690.022
Yeast Mouse
positive regulation of nucleotide catabolic processGO:0030813880.022
Yeast Mouse
epidermis developmentGO:00085441870.022
positive regulation of defense responseGO:00313491240.022
aromatic compound catabolic processGO:00194392860.022
Yeast Mouse
synaptic transmissionGO:00072683290.022
camera type eye developmentGO:00430102660.022
protein autophosphorylationGO:0046777610.022
cellular protein catabolic processGO:00442571550.022
ribonucleotide metabolic processGO:00092592910.022
Yeast Mouse
divalent inorganic cation transportGO:00725111780.021
mesodermal cell migrationGO:000807840.021
ribonucleoside triphosphate catabolic processGO:00092031990.021
Yeast Mouse
spermatogenesisGO:00072832840.021
photoreceptor cell morphogenesisGO:000859430.021
lipid catabolic processGO:0016042690.021
regulation of establishment of protein localizationGO:00702011810.021
negative regulation of intracellular signal transductionGO:19025321670.021
positive regulation of map kinase activityGO:0043406840.021
negative regulation of apoptotic signaling pathwayGO:20012341040.020
sequestering of calcium ionGO:0051208180.020
mitochondrion organizationGO:00070051340.020
purine nucleotide catabolic processGO:00061952110.020
Yeast Mouse
synapse organizationGO:00508081250.020
negative regulation of endopeptidase activityGO:0010951440.020
regulation of cell cycleGO:00517262810.020
phospholipid metabolic processGO:0006644870.020
response to radiationGO:00093141650.020
multicellular organismal homeostasisGO:00488711640.020
purine ribonucleotide catabolic processGO:00091542080.020
Yeast Mouse
adult locomotory behaviorGO:0008344910.019
metal ion homeostasisGO:00550651890.019
regulation of defense responseGO:00313472330.019
phagocytosisGO:0006909660.019
peptidyl lysine modificationGO:0018205770.019
positive regulation of gtp catabolic processGO:0033126850.019
Yeast Mouse
regulation of cysteine type endopeptidase activityGO:2000116650.019
positive regulation of transferase activityGO:00513471670.019
calcium ion homeostasisGO:00550741270.019
glycerolipid metabolic processGO:00464861220.019
internal peptidyl lysine acetylationGO:0018393420.019
leukocyte activation involved in immune responseGO:00023661260.019
female meiosis chromosome segregationGO:001632110.019
myeloid leukocyte differentiationGO:00025731190.019
respiratory system developmentGO:00605411900.019
positive regulation of bindingGO:0051099490.019
nucleoside triphosphate metabolic processGO:00091412300.019
Yeast Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.018
positive regulation of purine nucleotide catabolic processGO:0033123880.018
Yeast Mouse
lateral line system developmentGO:004892510.018
positive regulation of cell adhesionGO:0045785800.018
organic hydroxy compound metabolic processGO:19016152030.018
peptidyl serine modificationGO:0018209830.018
regulation of cytoplasmic transportGO:19036491120.018
regulation of ion transmembrane transportGO:00347651190.018
positive regulation of protein kinase activityGO:00458601440.018
regulation of protein processingGO:0070613960.018
mitotic cell cycle processGO:19030471590.018
positive regulation of protein serine threonine kinase activityGO:00719021060.017
amide transportGO:00428861380.017
regulation of mapk cascadeGO:00434082480.017
sensory system developmentGO:004888030.017
regulation of cytokine productionGO:00018172660.017
actin filament bundle assemblyGO:0051017400.017
meiotic cell cycleGO:00513211220.017
chromatin organizationGO:00063252060.017
positive regulation of cell developmentGO:00107202370.017
regulation of t cell activationGO:00508631700.017
heart processGO:0003015940.017
g protein coupled receptor signaling pathwayGO:00071862430.017
retrograde transport endosome to golgiGO:004214720.017
regulation of peptidase activityGO:0052547960.017
oxidation reduction processGO:00551143420.017
single organism cell adhesionGO:00986021560.017
erk1 and erk2 cascadeGO:0070371770.017
positive regulation of gtpase activityGO:0043547850.016
Yeast Mouse
regulation of lymphocyte activationGO:00512492400.016
cellular homeostasisGO:00197252400.016
nucleoside phosphate catabolic processGO:19012922220.016
Yeast Mouse
positive regulation of cell activationGO:00508671580.016
negative regulation of phosphate metabolic processGO:00459361840.016
response to light stimulusGO:00094161350.016
response to peptideGO:19016521360.016
protein polymerizationGO:0051258570.016
regulation of protein maturationGO:1903317960.016
regulation of leukocyte differentiationGO:19021051590.016
regulation of protein complex assemblyGO:0043254830.016
maintenance of locationGO:0051235890.016
divalent metal ion transportGO:00708381720.016
purine ribonucleoside metabolic processGO:00461282410.016
Yeast Mouse
inflammatory responseGO:00069542440.016
regulation of protein bindingGO:0043393600.016
negative regulation of immune system processGO:00026832090.016
positive regulation of innate immune responseGO:0045089800.016
negative regulation of protein tyrosine kinase activityGO:006109930.016
peptidyl threonine phosphorylationGO:0018107310.016
striated muscle tissue developmentGO:00147062930.016
extrinsic apoptotic signaling pathwayGO:00971911260.015
regulation of metal ion transportGO:00109591060.015
regulation of myeloid cell differentiationGO:0045637960.015
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858240.015
positive regulation of nervous system developmentGO:00519622210.015
cellular chemical homeostasisGO:00550822150.015
lymphocyte mediated immunityGO:00024491390.015
homeostasis of number of cellsGO:00488722100.015
Mouse
mitotic cell cycleGO:00002781950.015
purine ribonucleoside triphosphate metabolic processGO:00092052200.015
Yeast Mouse
tissue remodelingGO:00487711020.015
digestive tract developmentGO:00485651900.015
sensory organ morphogenesisGO:00905962420.015
regulation of nucleoside metabolic processGO:00091181300.015
Yeast Mouse
establishment of organelle localizationGO:00516561220.015
regulation of secretionGO:00510462740.015
regulation of neuron apoptotic processGO:00435231220.015
cognitionGO:00508901490.015
zygotic determination of anterior posterior axis embryoGO:000735430.015
regulation of ion transportGO:00432692150.015
peptide transportGO:00158331330.015
establishment of protein localization to plasma membraneGO:0090002340.015
peptidyl serine phosphorylationGO:0018105740.015
regulation of intracellular protein transportGO:0033157820.014
cell substrate adhesionGO:00315891300.014
positive regulation of lymphocyte activationGO:00512511400.014
b cell differentiationGO:0030183780.014
protein acylationGO:0043543640.014
cellular response to hormone stimulusGO:00328701500.014
negative regulation of proteolysisGO:0045861740.014
positive regulation of cytoskeleton organizationGO:0051495490.014
regulation of hormone levelsGO:00108172110.014
reactive nitrogen species metabolic processGO:200105700.014
cellular response to growth factor stimulusGO:00713631970.014
establishment of protein localization to membraneGO:0090150540.014
rho protein signal transductionGO:0007266320.014
regulation of histone modificationGO:0031056560.014
blood circulationGO:00080151950.014
regulation of protein transportGO:00512231630.014
internal protein amino acid acetylationGO:0006475420.014
lipid phosphorylationGO:0046834250.014
detection of external stimulusGO:0009581610.014
negative regulation of protein maturationGO:1903318790.014
peptide hormone secretionGO:00300721090.014
regulation of cellular component sizeGO:00325351210.014
engulfment of apoptotic cellGO:004365230.014
digestive system developmentGO:00551232000.014
muscle cell differentiationGO:00426922610.014
protein polyubiquitinationGO:0000209330.014
regulation of cell growthGO:0001558910.014
regulation of cell adhesionGO:00301551540.013
blood vessel morphogenesisGO:00485142850.013
lung developmentGO:00303241640.013
exocytosisGO:00068871210.013
golgi to endosome transportGO:000689530.013
cell activation involved in immune responseGO:00022631260.013
glycoprotein metabolic processGO:00091001160.013
lymphocyte differentiationGO:00300982420.013
skeletal muscle organ developmentGO:00605381630.013
negative regulation of synapse assemblyGO:005196430.013
compound eye developmentGO:004874910.013
heart morphogenesisGO:00030071780.013
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.013
regulation of chromosome organizationGO:0033044830.013
purine containing compound metabolic processGO:00725213110.013
Yeast Mouse
cell divisionGO:00513011200.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
Yeast Mouse
nucleocytoplasmic transportGO:00069131390.013
carbohydrate metabolic processGO:00059752300.013
regulation of sequence specific dna binding transcription factor activityGO:00510901060.013
regulation of anatomical structure sizeGO:00900661780.013
detection of abiotic stimulusGO:0009582600.013
positive regulation of cellular component biogenesisGO:0044089940.013
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascadeGO:003816810.013
multicellular organism growthGO:00352641610.013
positive regulation of dna templated transcription elongationGO:003278620.013
negative regulation of organelle organizationGO:0010639900.013
muscle tissue developmentGO:00605373080.013
negative regulation of protein processingGO:0010955790.013
mitotic cytokinesisGO:000028140.013
regulation of system processGO:00440572000.013
sensory perceptionGO:00076002450.013
calcium ion transmembrane transportGO:0070588850.013
regulation of actin cytoskeleton organizationGO:0032956840.013
regulation of neuron deathGO:19012141340.013
microtubule cytoskeleton organizationGO:00002261570.013
renal system developmentGO:00720012250.012
calcium ion transportGO:00068161590.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.012
dendrite developmentGO:00163581150.012
response to oxygen levelsGO:0070482620.012
regulation of chromatin modificationGO:1903308570.012
glycerophospholipid metabolic processGO:0006650710.012
cellular response to carbohydrate stimulusGO:0071322500.012
regulation of transporter activityGO:0032409570.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.012
positive regulation of ras gtpase activityGO:0032320650.012
neuron deathGO:00709971540.012
regulation of secretion by cellGO:19035302490.012
regulation of leukocyte mediated immunityGO:00027031040.012
adult behaviorGO:00305341350.012
cellular calcium ion homeostasisGO:00068741190.012
divalent inorganic cation homeostasisGO:00725071380.012
morphogenesis of embryonic epitheliumGO:00163311590.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.012
posttranscriptional regulation of gene expressionGO:00106081550.012
bone remodelingGO:0046849530.012
negative regulation of immune effector processGO:0002698550.012
cell fate commitmentGO:00451652100.012
lateral inhibitionGO:004633110.012
positive regulation of cellular catabolic processGO:00313311480.012
Yeast Mouse
meiotic cell cycle processGO:1903046770.012
nucleotide catabolic processGO:00091662170.012
Yeast Mouse
dna metabolic processGO:00062593030.012
regulation of lymphocyte mediated immunityGO:0002706840.012
single organismal cell cell adhesionGO:00163371310.012
positive regulation of nucleotide metabolic processGO:00459811140.012
Yeast Mouse
regulation of circadian sleep wake cycle sleepGO:004518730.012
positive regulation of kinase activityGO:00336741550.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
regulation of reactive oxygen species metabolic processGO:2000377400.011
intra golgi vesicle mediated transportGO:000689110.011
Yeast
regulation of leukocyte mediated cytotoxicityGO:0001910380.011
small molecule catabolic processGO:0044282710.011
negative regulation of growthGO:0045926990.011
glucose homeostasisGO:00425931280.011
neuron apoptotic processGO:00514021420.011
regulation of receptor activityGO:0010469410.011
t cell proliferationGO:00420981200.011
locomotory behaviorGO:00076261950.011
circulatory system processGO:00030131970.011
response to reactive oxygen speciesGO:0000302560.011
response to inorganic substanceGO:0010035960.011
urogenital system developmentGO:00016552610.011
organic hydroxy compound transportGO:0015850930.011
respiratory tube developmentGO:00303231670.011
establishment or maintenance of cell polarityGO:0007163860.011
response to molecule of bacterial originGO:00022371430.011
neural tube developmentGO:00219151600.011
regulation of actin filament lengthGO:0030832450.011
regulation of striated muscle cell differentiationGO:0051153810.011
protein localization to endosomeGO:003601020.011
positive regulation of rho gtpase activityGO:0032321410.011
skeletal system developmentGO:00015013560.011
cytokine productionGO:00018163190.011
immune response regulating cell surface receptor signaling pathwayGO:0002768800.011
regulation of androgen receptor signaling pathwayGO:006076530.011
sphingolipid metabolic processGO:0006665450.011
regionalizationGO:00030023370.011
response to organic cyclic compoundGO:00140701980.011
regulation of protein modification by small protein conjugation or removalGO:1903320570.011
regulation of peptide transportGO:0090087910.011
lipid localizationGO:00108761260.011
positive regulation of organelle organizationGO:00106381280.011
cytokine metabolic processGO:0042107710.011
regulation of erk1 and erk2 cascadeGO:0070372710.011
asymmetric neuroblast divisionGO:005505910.011
regulation of cell projection organizationGO:00313442060.011
leukocyte migrationGO:00509001240.011
regulation of t cell differentiationGO:0045580830.011
regulation of cell migrationGO:00303342190.011
cellular response to extracellular stimulusGO:0031668810.011
regulation of actin nucleationGO:005112540.011
tube formationGO:00351481400.011
regulation of muscle contractionGO:0006937490.011
cellular response to peptide hormone stimulusGO:0071375920.011
negative regulation of phosphorylationGO:00423261660.011
regulation of cellular component biogenesisGO:00440871810.011
calcium ion transport into cytosolGO:0060402480.011
guanosine containing compound catabolic processGO:19010691440.011
Yeast Mouse
regulation of cytoskeleton organizationGO:00514931220.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
Yeast Mouse
tissue homeostasisGO:00018941150.010
small molecule biosynthetic processGO:00442831320.010
positive regulation of nucleoside metabolic processGO:0045979910.010
Yeast Mouse
regulation of cell shapeGO:0008360390.010
vesicle localizationGO:0051648860.010
cellular response to ethanolGO:007136130.010
peptidyl lysine acetylationGO:0018394450.010
organonitrogen compound biosynthetic processGO:19015661920.010
regulation of response to drugGO:200102320.010
cell killingGO:0001906670.010
rab protein signal transductionGO:003248210.010
adult walking behaviorGO:0007628410.010
hormone secretionGO:00468791280.010
regulation of arp2 3 complex mediated actin nucleationGO:003431510.010
receptor recyclingGO:0001881110.010
regulation of lymphocyte differentiationGO:00456191070.010
anion transportGO:00068201770.010
carboxylic acid transportGO:00469421000.010
proteasomal protein catabolic processGO:0010498980.010

Smap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.030
central nervous system diseaseDOID:33100.025
inherited metabolic disorderDOID:65500.016
disease of metabolismDOID:001466700.016
neurodegenerative diseaseDOID:128900.015
immune system diseaseDOID:291400.014
brain diseaseDOID:93600.011
cardiovascular system diseaseDOID:128700.010
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010