Mus musculus

0 known processes

Trhde

TRH-degrading enzyme

(Aliases: MGC40831,9330155P21Rik)

Trhde biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072683290.176
ion transmembrane transportGO:00342203610.174
transmembrane transportGO:00550854120.116
axonogenesisGO:00074092740.090
cation transportGO:00068123990.090
regulation of membrane potentialGO:00423911920.089
inorganic cation transmembrane transportGO:00986622070.088
cellular amino acid metabolic processGO:00065201030.087
inorganic ion transmembrane transportGO:00986602340.081
neuron neuron synaptic transmissionGO:0007270690.077
forebrain developmentGO:00309003020.067
cellular ketone metabolic processGO:0042180840.065
regionalizationGO:00030023370.064
g protein coupled receptor signaling pathwayGO:00071862430.062
organonitrogen compound biosynthetic processGO:19015661920.059
regulation of cellular ketone metabolic processGO:0010565660.059
cation transmembrane transportGO:00986552660.057
telencephalon developmentGO:00215371860.056
regulation of system processGO:00440572000.056
skeletal system developmentGO:00015013560.055
purine nucleotide metabolic processGO:00061633020.054
locomotory behaviorGO:00076261950.051
amine metabolic processGO:0009308450.051
cell type specific apoptotic processGO:00972852680.047
regulation of cellular amino acid metabolic processGO:000652150.045
regulation of anatomical structure sizeGO:00900661780.043
cognitionGO:00508901490.043
positive regulation of cell developmentGO:00107202370.042
positive regulation of nervous system developmentGO:00519622210.042
peptidyl amino acid modificationGO:00181933360.041
transmission of nerve impulseGO:0019226760.041
regulation of transmembrane transportGO:00347621280.041
learningGO:0007612980.040
neuron migrationGO:00017641220.040
regulation of cell projection organizationGO:00313442060.039
regulation of postsynaptic membrane potentialGO:0060078480.039
action potentialGO:0001508780.039
regulation of neuron differentiationGO:00456642810.038
learning or memoryGO:00076111480.037
regulation of cellular amine metabolic processGO:0033238200.037
regulation of neuron projection developmentGO:00109751690.037
positive regulation of neuron differentiationGO:00456661410.036
membrane depolarizationGO:0051899640.035
camera type eye developmentGO:00430102660.035
cellular lipid metabolic processGO:00442553230.035
negative regulation of nervous system developmentGO:00519611560.034
negative regulation of molecular functionGO:00440922580.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
circulatory system processGO:00030131970.033
anion transportGO:00068201770.033
regulation of synaptic plasticityGO:0048167870.033
ribose phosphate metabolic processGO:00196932910.033
cellular amine metabolic processGO:0044106440.032
nucleotide metabolic processGO:00091173320.032
adult behaviorGO:00305341350.032
carbohydrate derivative biosynthetic processGO:19011371830.031
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.030
Mouse
regulation of cell cycleGO:00517262810.030
neuron apoptotic processGO:00514021420.029
nucleoside phosphate metabolic processGO:00067533380.029
renal system developmentGO:00720012250.029
Mouse
regulation of ion transportGO:00432692150.029
ribonucleotide metabolic processGO:00092592910.029
nucleobase containing small molecule metabolic processGO:00550863520.029
multicellular organismal response to stressGO:0033555620.028
ras protein signal transductionGO:0007265770.028
positive regulation of cellular amine metabolic processGO:003324050.028
cell adhesionGO:00071553290.028
response to organonitrogen compoundGO:00102432460.028
negative regulation of cellular component organizationGO:00511291940.028
muscle tissue developmentGO:00605373080.027
multicellular organismal signalingGO:0035637910.027
neuronal action potentialGO:0019228540.027
spermatogenesisGO:00072832840.027
adult locomotory behaviorGO:0008344910.026
mapk cascadeGO:00001652810.026
carbohydrate metabolic processGO:00059752300.026
nitrogen compound transportGO:00717052710.026
neuron deathGO:00709971540.026
cerebellum developmentGO:0021549770.026
cellular response to organonitrogen compoundGO:00714171450.026
regulation of defense responseGO:00313472330.025
central nervous system neuron differentiationGO:00219531620.025
developmental growth involved in morphogenesisGO:00605601380.025
regulation of secretion by cellGO:19035302490.025
regulation of neuron deathGO:19012141340.025
organophosphate biosynthetic processGO:00904071220.024
hindbrain developmentGO:00309021280.024
positive regulation of protein phosphorylationGO:00019342420.024
cellular metal ion homeostasisGO:00068751510.024
glial cell differentiationGO:00100011310.024
regulation of nucleotide metabolic processGO:00061401690.024
neuromuscular processGO:0050905990.024
cellular homeostasisGO:00197252400.024
small gtpase mediated signal transductionGO:0007264970.024
purine containing compound metabolic processGO:00725213110.024
negative regulation of cellular protein metabolic processGO:00322692470.023
respiratory tube developmentGO:00303231670.023
carboxylic acid transportGO:00469421000.023
developmental maturationGO:00217001930.023
striated muscle tissue developmentGO:00147062930.023
microtubule based processGO:00070172360.023
neurotransmitter secretionGO:0007269620.023
tube formationGO:00351481400.022
divalent inorganic cation transportGO:00725111780.022
calcium ion transportGO:00068161590.022
inflammatory responseGO:00069542440.022
apoptotic signaling pathwayGO:00971903060.022
oxidation reduction processGO:00551143420.022
organic anion transportGO:00157111370.022
ossificationGO:00015032160.022
purine ribonucleotide metabolic processGO:00091502900.022
male gamete generationGO:00482322850.022
digestive system developmentGO:00551232000.022
memoryGO:0007613580.022
negative regulation of neuron apoptotic processGO:0043524920.022
response to organic cyclic compoundGO:00140701980.022
organelle localizationGO:00516401790.021
regulation of kinase activityGO:00435492490.021
response to radiationGO:00093141650.021
regulation of voltage gated calcium channel activityGO:190138540.021
conditioned taste aversionGO:000166140.021
gland developmentGO:00487323300.021
regulation of neurotransmitter levelsGO:0001505870.021
glucose homeostasisGO:00425931280.021
cellular response to lipidGO:00713961450.021
muscle system processGO:00030121410.021
negative regulation of neuron differentiationGO:00456651010.020
skeletal system morphogenesisGO:00487052030.020
positive regulation of cell projection organizationGO:0031346950.020
cerebral cortex developmentGO:0021987860.020
bone developmentGO:00603481200.020
monocarboxylic acid metabolic processGO:00327871910.020
macromolecule catabolic processGO:00090572810.020
Mouse
anatomical structure homeostasisGO:00602491450.020
regulation of cellular component biogenesisGO:00440871810.020
organic acid transportGO:00158491010.020
tissue homeostasisGO:00018941150.020
fatty acid metabolic processGO:00066311210.020
negative regulation of protein modification processGO:00314001630.020
metencephalon developmentGO:0022037890.020
nucleoside phosphate biosynthetic processGO:1901293790.019
regulation of transferase activityGO:00513382630.019
protein catabolic processGO:00301632210.019
Mouse
metal ion homeostasisGO:00550651890.019
cartilage developmentGO:00512161400.019
angiogenesisGO:00015252010.019
Mouse
cellular response to hormone stimulusGO:00328701500.019
extracellular matrix organizationGO:00301981470.019
negative regulation of protein metabolic processGO:00512482820.019
fertilizationGO:00095661270.019
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.019
negative regulation of phosphorus metabolic processGO:00105631840.019
immune effector processGO:00022523210.019
regulation of ossificationGO:00302781120.019
negative regulation of cellular amine metabolic processGO:003323910.019
wnt signaling pathwayGO:00160551880.018
membrane organizationGO:00610242450.018
heart morphogenesisGO:00030071780.018
homeostasis of number of cellsGO:00488722100.018
synapse organizationGO:00508081250.018
maintenance of locationGO:0051235890.018
positive regulation of protein modification processGO:00314012990.018
carbohydrate homeostasisGO:00335001280.018
connective tissue developmentGO:00614481790.018
regulation of mapk cascadeGO:00434082480.018
regulation of neuron apoptotic processGO:00435231220.018
glycoprotein metabolic processGO:00091001160.018
protein ubiquitinationGO:00165671710.018
regulation of purine nucleotide metabolic processGO:19005421690.018
segmentationGO:0035282930.018
fat cell differentiationGO:00454441600.018
organic acid biosynthetic processGO:0016053860.018
negative regulation of cell developmentGO:00107211690.017
kidney developmentGO:00018222130.017
Mouse
g protein coupled glutamate receptor signaling pathwayGO:000721630.017
purine nucleotide biosynthetic processGO:0006164650.017
positive regulation of neuron projection developmentGO:0010976790.017
neurotransmitter transportGO:0006836760.017
multi multicellular organism processGO:00447061090.017
divalent metal ion transportGO:00708381720.017
bone morphogenesisGO:0060349780.017
lung developmentGO:00303241640.017
heterocycle catabolic processGO:00467002800.017
regulation of homeostatic processGO:00328441820.017
urogenital system developmentGO:00016552610.017
Mouse
regulation of cell motilityGO:20001452360.017
skin developmentGO:00435882200.017
gliogenesisGO:00420631410.017
cation homeostasisGO:00550802120.017
sensory system developmentGO:004888030.017
lipid localizationGO:00108761260.017
establishment of organelle localizationGO:00516561220.017
response to growth factorGO:00708481980.017
regulation of hormone levelsGO:00108172110.017
peptide hormone secretionGO:00300721090.017
male sex differentiationGO:00466611090.017
sensory perceptionGO:00076002450.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
protein maturationGO:00516041760.017
reactive oxygen species metabolic processGO:0072593840.017
cellular response to organic cyclic compoundGO:0071407870.016
sensory perception of mechanical stimulusGO:00509541070.016
amide transportGO:00428861380.016
positive regulation of nucleotide metabolic processGO:00459811140.016
stem cell differentiationGO:00488632680.016
epithelial tube morphogenesisGO:00605623030.016
tube closureGO:0060606910.016
purine containing compound biosynthetic processGO:0072522700.016
muscle cell differentiationGO:00426922610.016
sensory organ morphogenesisGO:00905962420.016
epidermis developmentGO:00085441870.016
muscle contractionGO:00069361010.016
organic hydroxy compound transportGO:0015850930.016
regulation of cellular component sizeGO:00325351210.016
protein localization to organelleGO:00333651850.016
cytoplasmic transportGO:00164822340.016
positive regulation of purine nucleotide metabolic processGO:19005441140.016
cellular chemical homeostasisGO:00550822150.016
positive regulation of transferase activityGO:00513471670.016
regulation of transporter activityGO:0032409570.016
response to peptide hormoneGO:00434341270.016
nucleoside metabolic processGO:00091162460.016
heart processGO:0003015940.016
ribose phosphate biosynthetic processGO:0046390590.015
embryonic organ morphogenesisGO:00485622760.015
exocytosisGO:00068871210.015
extracellular structure organizationGO:00430621480.015
purine ribonucleotide biosynthetic processGO:0009152590.015
rhythmic processGO:00485111740.015
regulation of response to woundingGO:19030341890.015
cell divisionGO:00513011200.015
positive regulation of cellular component biogenesisGO:0044089940.015
regulation of secretionGO:00510462740.015
regulation of organelle organizationGO:00330432890.015
cyclic nucleotide metabolic processGO:0009187590.015
purine nucleoside metabolic processGO:00422782410.015
positive regulation of secretion by cellGO:19035321140.015
hormone secretionGO:00468791280.015
nucleotide biosynthetic processGO:0009165780.015
negative regulation of phosphate metabolic processGO:00459361840.015
regulation of cell morphogenesis involved in differentiationGO:00107691510.015
response to light stimulusGO:00094161350.015
limb morphogenesisGO:00351081490.015
lymphocyte differentiationGO:00300982420.015
spermatid developmentGO:00072861080.015
protein modification by small protein conjugation or removalGO:00706472070.015
epithelial tube formationGO:00721751300.015
blood circulationGO:00080151950.015
sulfur compound metabolic processGO:00067901000.015
innervationGO:0060384220.015
cellular response to growth factor stimulusGO:00713631970.015
epithelial cell proliferationGO:00506731740.015
positive regulation of cell cycleGO:0045787920.015
protein modification by small protein conjugationGO:00324461870.015
regulation of blood circulationGO:1903522930.015
positive regulation of secretionGO:00510471300.015
calcium ion transmembrane transportGO:0070588850.015
morphogenesis of embryonic epitheliumGO:00163311590.015
extrinsic apoptotic signaling pathwayGO:00971911260.015
cell maturationGO:00484691270.015
placenta developmentGO:00018901400.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
lymphocyte mediated immunityGO:00024491390.015
glycoprotein biosynthetic processGO:0009101890.015
lipid biosynthetic processGO:00086101790.015
carboxylic acid biosynthetic processGO:0046394860.015
positive regulation of cell deathGO:00109422240.015
cerebellar cortex developmentGO:0021695480.015
reactive oxygen species biosynthetic processGO:190340980.015
regulation of vesicle mediated transportGO:00606271390.015
cellular protein complex assemblyGO:00436231160.015
myelinationGO:0042552740.014
negative regulation of phosphorylationGO:00423261660.014
regulation of cell activationGO:00508652890.014
neuron projection extensionGO:1990138640.014
posttranscriptional regulation of gene expressionGO:00106081550.014
positive regulation of cell motilityGO:20001471160.014
digestive tract developmentGO:00485651900.014
myotube differentiationGO:00149021050.014
regulation of cell migrationGO:00303342190.014
pallium developmentGO:00215431200.014
small molecule biosynthetic processGO:00442831320.014
insulin metabolic processGO:190114230.014
cellular carbohydrate metabolic processGO:00442621190.014
male anatomical structure morphogenesisGO:009059840.014
rho protein signal transductionGO:0007266320.014
regulation of hydrolase activityGO:00513362460.014
regulation of cell growthGO:0001558910.014
positive regulation of mapk cascadeGO:00434101700.014
organic hydroxy compound metabolic processGO:19016152030.014
sensory perception of soundGO:0007605970.014
bmp signaling pathwayGO:0030509930.014
blood vessel morphogenesisGO:00485142850.014
Mouse
nucleotide catabolic processGO:00091662170.014
negative regulation of cell proliferationGO:00082852960.014
central nervous system neuron developmentGO:0021954670.014
embryonic epithelial tube formationGO:00018381300.014
regulation of ion transmembrane transportGO:00347651190.014
purine ribonucleoside triphosphate metabolic processGO:00092052200.014
calcium ion homeostasisGO:00550741270.014
intracellular protein transportGO:00068862040.013
organ growthGO:00352651170.013
sodium ion transportGO:0006814730.013
negative regulation of cellular amino acid metabolic processGO:004576300.013
oocyte axis specificationGO:000730920.013
regulation of epithelial cell proliferationGO:00506781410.013
positive regulation of homeostatic processGO:0032846640.013
regulation of cytokine productionGO:00018172660.013
reactive nitrogen species metabolic processGO:200105700.013
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.013
sodium ion transmembrane transportGO:0035725490.013
cellular ion homeostasisGO:00068731650.013
glycosyl compound metabolic processGO:19016572460.013
divalent inorganic cation homeostasisGO:00725071380.013
regulation of excitatory postsynaptic membrane potentialGO:0060079410.013
mesodermal cell migrationGO:000807840.013
limbic system developmentGO:0021761720.013
cellular response to abiotic stimulusGO:0071214560.013
aromatic compound catabolic processGO:00194392860.013
telencephalon cell migrationGO:0022029550.013
ear developmentGO:00435832000.013
habituationGO:004695930.013
gonad morphogenesisGO:003526210.013
positive regulation of apoptotic processGO:00430652170.013
negative regulation of intracellular signal transductionGO:19025321670.013
morphogenesis of a branching epitheliumGO:00611381930.013
regulation of protein serine threonine kinase activityGO:00719001570.013
positive regulation of programmed cell deathGO:00430682180.013
endocytosisGO:00068971680.013
negative regulation of cell cycleGO:00457861230.013
nucleoside triphosphate metabolic processGO:00091412300.013
developmental cell growthGO:0048588840.013
peptidyl lysine modificationGO:0018205770.013
substantia nigra developmentGO:002176220.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
endocrine system developmentGO:0035270980.013
regulation of blood vessel sizeGO:0050880560.013
respiratory system developmentGO:00605411900.013
regulation of blood pressureGO:0008217930.013
purine nucleotide catabolic processGO:00061952110.013
cytokine productionGO:00018163190.013
synaptic transmission glutamatergicGO:0035249360.013
purine ribonucleoside metabolic processGO:00461282410.012
regulation of cellular catabolic processGO:00313292420.012
cell growthGO:00160491300.012
regulation of reactive oxygen species biosynthetic processGO:190342620.012
epithelial cell developmentGO:00020641590.012
compound eye developmentGO:004874910.012
stem cell developmentGO:00488642190.012
neural tube formationGO:00018411080.012
morphogenesis of a branching structureGO:00017632030.012
covalent chromatin modificationGO:00165691630.012
nuclear transportGO:00511691390.012
negative regulation of growthGO:0045926990.012
stem cell maintenanceGO:00198271300.012
digestive tract morphogenesisGO:00485461470.012
leukocyte differentiationGO:00025213420.012
cardiac muscle tissue developmentGO:00487381300.012
t cell activationGO:00421102890.012
carbohydrate derivative catabolic processGO:19011362310.012
hormone metabolic processGO:0042445860.012
nerve developmentGO:0021675670.012
appendage developmentGO:00487361660.012
histone modificationGO:00165701590.012
ribonucleoside triphosphate metabolic processGO:00091992200.012
retina development in camera type eyeGO:00600411190.012
regulation of peptide secretionGO:0002791770.012
somite developmentGO:0061053810.012
microtubule cytoskeleton organizationGO:00002261570.012
intracellular mrna localizationGO:000829840.012
cell recognitionGO:0008037830.012
mesenchymal cell differentiationGO:00487621070.012
long term synaptic potentiationGO:0060291250.012
canonical wnt signaling pathwayGO:00600701300.012
cellular nitrogen compound catabolic processGO:00442702800.012
multicellular organismal homeostasisGO:00488711640.012
asymmetric stem cell divisionGO:009872230.012
regulation of action potentialGO:009890040.012
cardiac ventricle developmentGO:0003231830.012
connective tissue replacement involved in inflammatory response wound healingGO:000224830.012
nucleoside phosphate catabolic processGO:19012922220.012
male genitalia morphogenesisGO:004880840.012
regulation of organ morphogenesisGO:20000271440.012
negative regulation of neuron deathGO:1901215980.012
neuron projection guidanceGO:00974851410.012
regulation of heart contractionGO:0008016770.012
vascular process in circulatory systemGO:0003018620.012
protein processingGO:00164851630.012
leukocyte mediated immunityGO:00024431740.012
regulation of protein kinase activityGO:00458592320.012
fear responseGO:0042596330.012
glycerolipid metabolic processGO:00464861220.012
wound healingGO:00420601570.012
cyclic purine nucleotide metabolic processGO:0052652430.012
organic cyclic compound catabolic processGO:19013612950.012
cellular calcium ion homeostasisGO:00068741190.012
zygotic determination of anterior posterior axis embryoGO:000735430.012
anion transmembrane transportGO:0098656710.011
purine ribonucleoside triphosphate catabolic processGO:00092071990.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
chemotaxisGO:00069352470.011
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.011
regulation of extent of cell growthGO:0061387520.011
stem cell proliferationGO:00720891170.011
ribonucleotide biosynthetic processGO:0009260590.011
lipid transportGO:0006869980.011
regulation of feeding behaviorGO:006025930.011
response to molecule of bacterial originGO:00022371430.011
neural precursor cell proliferationGO:00613511210.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.011
regulation of wnt signaling pathwayGO:00301111230.011
sequestering of calcium ionGO:0051208180.011
regulation of synaptic growth at neuromuscular junctionGO:000858240.011
hexose metabolic processGO:0019318980.011
cell fate commitmentGO:00451652100.011
purine ribonucleoside catabolic processGO:00461302050.011
synaptic vesicle primingGO:001608280.011
associative learningGO:0008306610.011
mrna metabolic processGO:0016071840.011
female sex differentiationGO:0046660840.011
neural tube closureGO:0001843900.011
negative regulation of neuron projection developmentGO:0010977500.011
ensheathment of neuronsGO:0007272760.011
mitotic cell cycleGO:00002781950.011
regulation of proteolysisGO:00301621640.011
molting cycleGO:0042303900.011
regulation of inflammatory responseGO:00507271470.011
response to inorganic substanceGO:0010035960.011
regulation of ras protein signal transductionGO:00465781140.011
regulation of protein localizationGO:00328802310.011
determination of left right symmetryGO:0007368800.011
cellular response to ammonium ionGO:007124220.011
regulation of protein maturationGO:1903317960.011
positive regulation of cell adhesionGO:0045785800.011
monosaccharide metabolic processGO:00059961060.011
smoothened signaling pathwayGO:00072241050.011
skeletal muscle organ developmentGO:00605381630.011
response to acid chemicalGO:00011011110.011
positive regulation of growthGO:00459271040.011
appendage morphogenesisGO:00351071490.011
peptide secretionGO:00027901140.011
spinal cord motor neuron migrationGO:009747640.011
ameboidal type cell migrationGO:00016671280.011
regulation of cell sizeGO:0008361720.011
regulation of exocytosisGO:0017157610.011
hematopoietic progenitor cell differentiationGO:00022441430.011
neural tube developmentGO:00219151600.011
myeloid leukocyte differentiationGO:00025731190.011
b cell differentiationGO:0030183780.011
peptide transportGO:00158331330.011
regulation of cell substrate adhesionGO:0010810730.011
regulation of renin secretion into blood streamGO:190013340.011
regulation of reactive oxygen species metabolic processGO:2000377400.011
regulation of nucleoside metabolic processGO:00091181300.011
photoreceptor cell differentiationGO:0046530520.011
feeding behaviorGO:0007631620.011
glucose metabolic processGO:0006006920.011
single fertilizationGO:0007338820.010
forebrain cell migrationGO:0021885580.010
positive regulation of immune effector processGO:00026991070.010
potassium ion transportGO:0006813520.010
regulation of apoptotic signaling pathwayGO:20012331970.010
cellular response to transforming growth factor beta stimulusGO:0071560880.010
multicellular organism growthGO:00352641610.010
potassium ion transmembrane transportGO:0071805430.010
negative regulation of multi organism processGO:0043901680.010
regulation of neuronal synaptic plasticityGO:0048168300.010
intestinal epithelial structure maintenanceGO:006072940.010
organophosphate catabolic processGO:00464342320.010
ear morphogenesisGO:00424711180.010
regulation of cell cycle processGO:00105641600.010
maintenance of apical basal cell polarityGO:003509030.010
vesicle organizationGO:0016050600.010
dna metabolic processGO:00062593030.010
positive regulation of kinase activityGO:00336741550.010
rna splicingGO:0008380540.010
positive regulation of protein serine threonine kinase activityGO:00719021060.010
response to peptideGO:19016521360.010
nucleoside catabolic processGO:00091642060.010
branching morphogenesis of an epithelial tubeGO:00487541590.010
regulation of canonical wnt signaling pathwayGO:0060828820.010
purine ribonucleotide catabolic processGO:00091542080.010
sequestering of metal ionGO:0051238190.010
synaptic vesicle localizationGO:0097479590.010
detection of stimulusGO:0051606840.010

Trhde disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.036
eye diseaseDOID:561400.027
eye and adnexa diseaseDOID:149200.027
sensory system diseaseDOID:005015500.027
retinal degenerationDOID:846600.017
retinal diseaseDOID:567900.017
musculoskeletal system diseaseDOID:1700.016
central nervous system diseaseDOID:33100.014
cardiovascular system diseaseDOID:128700.013