Mus musculus

141 known processes

Fech

ferrochelatase

(Aliases: fch,Fcl,AI894116)

Fech biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cofactor biosynthetic processGO:0051188410.571
myeloid cell differentiationGO:00300992330.340
porphyrin containing compound biosynthetic processGO:0006779160.305
membrane organizationGO:00610242450.291
organonitrogen compound biosynthetic processGO:19015661920.282
tetrapyrrole metabolic processGO:0033013220.263
plasma membrane organizationGO:0007009900.224
axonogenesisGO:00074092740.212
porphyrin containing compound metabolic processGO:0006778220.196
erythrocyte differentiationGO:0030218880.193
endomembrane system organizationGO:00102561470.178
neuron projection guidanceGO:00974851410.157
protein localization to membraneGO:00726571080.129
cellular amino acid metabolic processGO:00065201030.126
protein localization to plasma membraneGO:0072659570.117
chemotaxisGO:00069352470.112
axon guidanceGO:00074111410.105
homeostasis of number of cellsGO:00488722100.100
regulation of transferase activityGO:00513382630.100
sulfur compound biosynthetic processGO:0044272370.099
cellular ketone metabolic processGO:0042180840.081
hindbrain developmentGO:00309021280.069
intracellular protein transportGO:00068862040.069
tetrapyrrole biosynthetic processGO:0033014160.068
response to radiationGO:00093141650.067
iron ion homeostasisGO:0055072360.067
amp metabolic processGO:004603340.065
single organism nuclear importGO:1902593950.062
glycerolipid metabolic processGO:00464861220.061
myeloid cell homeostasisGO:00022621140.060
proteolysis involved in cellular protein catabolic processGO:00516031470.055
negative regulation of protein metabolic processGO:00512482820.055
regulation of membrane potentialGO:00423911920.054
protein catabolic processGO:00301632210.053
cellular component assembly involved in morphogenesisGO:00109271390.053
cellular macromolecule catabolic processGO:00442652060.053
regulation of apoptotic signaling pathwayGO:20012331970.053
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:0014808120.051
protein targeting to plasma membraneGO:007266170.051
multicellular organism growthGO:00352641610.050
protein ubiquitinationGO:00165671710.050
dephosphorylationGO:00163111290.049
protein modification by small protein conjugation or removalGO:00706472070.049
nuclear divisionGO:00002801580.049
monocarboxylic acid metabolic processGO:00327871910.046
metencephalon developmentGO:0022037890.046
response to oxidative stressGO:00069791230.046
regulation of protein serine threonine kinase activityGO:00719001570.045
regulation of cellular amino acid metabolic processGO:000652150.045
transmembrane transportGO:00550854120.045
cellular ion homeostasisGO:00068731650.044
organic acid biosynthetic processGO:0016053860.043
alcohol metabolic processGO:00060661160.042
positive regulation of potassium ion transportGO:004326830.042
regulation of cellular ketone metabolic processGO:0010565660.042
defecationGO:003042110.040
cellular lipid metabolic processGO:00442553230.040
transition metal ion homeostasisGO:0055076540.039
ras protein signal transductionGO:0007265770.039
positive regulation of growthGO:00459271040.038
negative regulation of phosphorus metabolic processGO:00105631840.038
regulation of cellular response to stressGO:00801351590.038
negative regulation of molecular functionGO:00440922580.038
adiponectin activated signaling pathwayGO:003321140.038
cerebellum developmentGO:0021549770.036
response to nutrient levelsGO:00316671090.036
developmental maturationGO:00217001930.036
Zebrafish
regulation of system processGO:00440572000.034
cellular response to oxidative stressGO:0034599760.033
anion transportGO:00068201770.033
negative regulation of heart rateGO:001045940.033
apoptotic signaling pathwayGO:00971903060.032
sensory perceptionGO:00076002450.032
organic anion transportGO:00157111370.032
regulation of kinase activityGO:00435492490.032
mitotic cell cycle processGO:19030471590.032
cellular amine metabolic processGO:0044106440.030
intrinsic apoptotic signaling pathwayGO:00971931320.030
amine metabolic processGO:0009308450.030
transmission of nerve impulseGO:0019226760.030
positive regulation of potassium ion transmembrane transporter activityGO:190101810.030
sulfur compound metabolic processGO:00067901000.030
heme biosynthetic processGO:0006783120.029
nuclear transportGO:00511691390.029
negative regulation of cellular protein metabolic processGO:00322692470.029
regulation of cellular amine metabolic processGO:0033238200.028
response to iron ionGO:001003940.028
sequestering of metal ionGO:0051238190.028
regulation of intracellular transportGO:00323861590.028
mitochondrion transport along microtubuleGO:004749730.028
oxidation reduction processGO:00551143420.027
protein import into nucleusGO:0006606950.026
negative regulation of phosphorylationGO:00423261660.026
peptidyl amino acid modificationGO:00181933360.026
regulation of cytolysisGO:004226810.025
response to light stimulusGO:00094161350.025
regulation of ion transportGO:00432692150.025
modification dependent macromolecule catabolic processGO:00436321330.025
response to inorganic substanceGO:0010035960.025
hydrogen peroxide catabolic processGO:004274450.024
positive regulation of leukocyte proliferationGO:0070665730.024
carboxylic acid biosynthetic processGO:0046394860.024
protein processingGO:00164851630.024
ribose phosphate metabolic processGO:00196932910.024
cellular metal ion homeostasisGO:00068751510.024
fertilizationGO:00095661270.023
ubiquitin dependent protein catabolic processGO:00065111290.023
cellular response to hormone stimulusGO:00328701500.023
negative regulation of protein modification processGO:00314001630.023
positive regulation of reactive oxygen species metabolic processGO:2000379110.023
positive regulation of cellular amine metabolic processGO:003324050.023
response to growth factorGO:00708481980.023
blood circulationGO:00080151950.023
small molecule biosynthetic processGO:00442831320.023
modification dependent protein catabolic processGO:00199411330.023
purine nucleotide metabolic processGO:00061633020.023
ribonucleotide metabolic processGO:00092592910.022
cation transmembrane transportGO:00986552660.022
metal ion homeostasisGO:00550651890.022
nuclear importGO:0051170950.022
acylglycerol metabolic processGO:0006639550.022
nucleobase containing small molecule metabolic processGO:00550863520.022
protein modification by small protein conjugationGO:00324461870.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
inorganic ion transmembrane transportGO:00986602340.022
sa node cell to atrial cardiac muscle cell signallingGO:008601840.021
protein oligomerizationGO:0051259670.021
generation of precursor metabolites and energyGO:00060911030.021
carbohydrate derivative biosynthetic processGO:19011371830.021
response to extracellular stimulusGO:00099911270.021
phospholipid metabolic processGO:0006644870.021
cell maturationGO:00484691270.021
Zebrafish
regulation of cell activationGO:00508652890.021
regulation of cellular catabolic processGO:00313292420.020
cellular response to growth factor stimulusGO:00713631970.020
macromolecule catabolic processGO:00090572810.020
organelle assemblyGO:00709251770.020
response to starvationGO:0042594650.020
purine ribonucleotide metabolic processGO:00091502900.020
atp metabolic processGO:0046034750.020
cellular protein catabolic processGO:00442571550.020
divalent inorganic cation homeostasisGO:00725071380.020
negative regulation of intracellular signal transductionGO:19025321670.020
nucleoside metabolic processGO:00091162460.020
locomotory behaviorGO:00076261950.019
nucleocytoplasmic transportGO:00069131390.019
negative regulation of phosphate metabolic processGO:00459361840.019
cerebellar cortex morphogenesisGO:0021696320.019
cerebellum morphogenesisGO:0021587420.019
neutral lipid metabolic processGO:0006638570.019
triglyceride metabolic processGO:0006641510.019
carbohydrate metabolic processGO:00059752300.019
regulation of protein processingGO:0070613960.019
reactive oxygen species metabolic processGO:0072593840.019
organelle fissionGO:00482851700.019
regulation of heart contractionGO:0008016770.019
central nervous system neuron differentiationGO:00219531620.018
hormone mediated signaling pathwayGO:0009755230.018
cellular chemical homeostasisGO:00550822150.018
negative regulation of transferase activityGO:0051348850.018
spermatogenesisGO:00072832840.018
purine containing compound metabolic processGO:00725213110.018
cytoplasmic transportGO:00164822340.018
action potentialGO:0001508780.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.018
glycerophospholipid metabolic processGO:0006650710.018
t cell proliferationGO:00420981200.018
microtubule based processGO:00070172360.017
mitotic cell cycleGO:00002781950.017
monocarboxylic acid transportGO:0015718440.017
cell type specific apoptotic processGO:00972852680.017
ribonucleoside triphosphate metabolic processGO:00091992200.017
regulation of leukocyte proliferationGO:00706631210.017
regulation of cytokine productionGO:00018172660.017
negative regulation of homeostatic processGO:0032845710.017
adult behaviorGO:00305341350.017
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:0010880100.017
neuronal action potentialGO:0019228540.017
multicellular organismal homeostasisGO:00488711640.017
cerebellar purkinje cell layer developmentGO:0021680260.017
protein targetingGO:00066051430.017
cation homeostasisGO:00550802120.016
purine nucleoside triphosphate metabolic processGO:00091442260.016
regulation of cellular response to growth factor stimulusGO:0090287820.016
regulation of nucleotide catabolic processGO:00308111220.016
regulation of lymphocyte proliferationGO:00506701170.016
establishment of protein localization to membraneGO:0090150540.016
protein homooligomerizationGO:0051260430.016
positive regulation of purine nucleotide metabolic processGO:19005441140.016
purine nucleotide catabolic processGO:00061952110.016
negative regulation of protein activation cascadeGO:200025830.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.016
negative regulation of complement activationGO:004591630.016
lipid biosynthetic processGO:00086101790.016
sensory perception of mechanical stimulusGO:00509541070.016
response to reactive oxygen speciesGO:0000302560.016
pyruvate transportGO:000684820.016
organic hydroxy compound metabolic processGO:19016152030.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
establishment of protein localization to organelleGO:00725941180.015
nucleoside phosphate metabolic processGO:00067533380.015
signal transduction in absence of ligandGO:0038034550.015
regulation of organelle organizationGO:00330432890.015
cerebellar cortex developmentGO:0021695480.015
purine nucleoside metabolic processGO:00422782410.015
fibroblast growth factor receptor signaling pathwayGO:0008543460.015
carboxylic acid transportGO:00469421000.015
response to metal ionGO:0010038470.015
regulation of reactive oxygen species biosynthetic processGO:190342620.015
nucleoside monophosphate metabolic processGO:0009123850.015
cellular amino acid biosynthetic processGO:0008652220.015
regulation of bindingGO:00510981110.015
forebrain developmentGO:00309003020.015
multicellular organismal signalingGO:0035637910.015
myeloid leukocyte differentiationGO:00025731190.015
ribonucleoside metabolic processGO:00091192450.015
heart contractionGO:0060047930.014
regulation of transmembrane transportGO:00347621280.014
purine ribonucleoside metabolic processGO:00461282410.014
activation of membrane attack complexGO:000190540.014
divalent inorganic cation transportGO:00725111780.014
muscle cell differentiationGO:00426922610.014
adult locomotory behaviorGO:0008344910.014
positive regulation of programmed cell deathGO:00430682180.014
regulation of protein bindingGO:0043393600.014
fatty acid metabolic processGO:00066311210.014
hindbrain morphogenesisGO:0021575460.014
multi organism behaviorGO:0051705620.014
regulation of t cell activationGO:00508631700.014
nonribosomal peptide biosynthetic processGO:001918450.014
dna endoreduplicationGO:004202340.014
regulation of protein localizationGO:00328802310.014
striated muscle tissue developmentGO:00147062930.013
regulation of protein kinase activityGO:00458592320.013
regulation of protein maturationGO:1903317960.013
regulation of mapk cascadeGO:00434082480.013
protein importGO:00170381010.013
muscle tissue developmentGO:00605373080.013
regulation of leukocyte differentiationGO:19021051590.013
negative regulation of cellular amine metabolic processGO:003323910.013
response to organonitrogen compoundGO:00102432460.013
divalent metal ion transportGO:00708381720.013
digestive tract developmentGO:00485651900.013
multicellular organismal agingGO:0010259240.013
calcium ion homeostasisGO:00550741270.013
cellular modified amino acid metabolic processGO:0006575630.013
cellular response to cytokine stimulusGO:00713451890.013
organophosphate biosynthetic processGO:00904071220.012
cell cycle g1 s phase transitionGO:0044843570.012
negative regulation of organelle organizationGO:0010639900.012
organic cyclic compound catabolic processGO:19013612950.012
calcium ion transportGO:00068161590.012
sequestering of calcium ionGO:0051208180.012
guanosine containing compound metabolic processGO:19010681440.012
endocytic recyclingGO:003245670.012
nucleoside phosphate biosynthetic processGO:1901293790.012
negative regulation of cell cycleGO:00457861230.012
ossificationGO:00015032160.012
mapk cascadeGO:00001652810.012
response to molecule of bacterial originGO:00022371430.012
nucleotide biosynthetic processGO:0009165780.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.012
negative regulation of protein processingGO:0010955790.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
neuron deathGO:00709971540.012
organic acid transportGO:00158491010.012
immune effector processGO:00022523210.012
thioester biosynthetic processGO:003538470.012
lymphocyte proliferationGO:00466511640.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
synapse organizationGO:00508081250.012
purine nucleotide biosynthetic processGO:0006164650.012
regulation of cell cycleGO:00517262810.012
paracrine signalingGO:003800110.012
liver developmentGO:0001889660.011
protein acylationGO:0043543640.011
small gtpase mediated signal transductionGO:0007264970.011
multi multicellular organism processGO:00447061090.011
heart morphogenesisGO:00030071780.011
negative regulation of kinase activityGO:0033673810.011
negative regulation of protein phosphorylationGO:00019331260.011
cation transportGO:00068123990.011
protein localization to nucleusGO:00345041210.011
regulation of t cell proliferationGO:0042129920.011
glycosyl compound metabolic processGO:19016572460.011
xenobiotic catabolic processGO:004217810.011
positive regulation of lymphocyte proliferationGO:0050671700.011
positive regulation of gtpase activityGO:0043547850.011
anatomical structure homeostasisGO:00602491450.011
protein targeting to membraneGO:0006612200.011
lipoprotein metabolic processGO:0042157430.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
meiotic cell cycleGO:00513211220.011
neural tube closureGO:0001843900.011
water soluble vitamin metabolic processGO:0006767100.011
positive regulation of protein modification processGO:00314012990.011
cellular response to arsenic containing substanceGO:007124340.011
regulation of cardiac muscle cell membrane potentialGO:008603630.011
wnt signaling pathwayGO:00160551880.011
negative regulation of dna replicationGO:000815640.011
stem cell maintenanceGO:00198271300.011
fibroblast growth factor productionGO:009026940.011
male gamete generationGO:00482322850.011
long chain fatty acid importGO:004453920.011
myelinationGO:0042552740.011
negative regulation of immune system processGO:00026832090.011
heart processGO:0003015940.011
ion transmembrane transportGO:00342203610.011
reactive nitrogen species metabolic processGO:200105700.011
nucleoside phosphate catabolic processGO:19012922220.011
nitrogen compound transportGO:00717052710.010
response to organic cyclic compoundGO:00140701980.010
ribonucleotide biosynthetic processGO:0009260590.010
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.010
regulation of defense responseGO:00313472330.010
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.010
purine nucleoside monophosphate metabolic processGO:0009126810.010
activation of immune responseGO:00022531380.010
regulation of ras protein signal transductionGO:00465781140.010
circulatory system processGO:00030131970.010
glycoprotein biosynthetic processGO:0009101890.010
striated muscle cell developmentGO:00550021250.010
retrograde vesicle mediated transport golgi to erGO:000689010.010
actin mediated cell contractionGO:0070252150.010
heterocycle catabolic processGO:00467002800.010
organophosphate catabolic processGO:00464342320.010
purine ribonucleoside catabolic processGO:00461302050.010
purine containing compound biosynthetic processGO:0072522700.010
rho protein signal transductionGO:0007266320.010
organic hydroxy compound catabolic processGO:1901616250.010

Fech disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
anemiaDOID:235500.513
immune system diseaseDOID:291400.513
hematopoietic system diseaseDOID:7400.513
disease of anatomical entityDOID:700.513
disease of metabolismDOID:001466700.169
inherited metabolic disorderDOID:65500.080
nervous system diseaseDOID:86300.048
central nervous system diseaseDOID:33100.041
normocytic anemiaDOID:72000.025
hemolytic anemiaDOID:58300.025
neurodegenerative diseaseDOID:128900.023
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014
cancerDOID:16200.010
disease of cellular proliferationDOID:1456600.010
eye diseaseDOID:561400.010