IMP: Integrative Multi-species Prediction

Mus musculus

116 known processes

Bdkrb2

bradykinin receptor, beta 2

(Aliases: B(2),BK-2,BK2R,BRB2,B2,B2R,BK2,BKR2)

Ensembl: ENSMUSG00000021070
Entrez: 12062
UniProtKB: P32299

Process Predictions
Disease Predictions

Bdkrb2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
renin angiotensin regulation of aldosterone production	GO:0002018	3	0.967	Mouse
regulation of cellular amine metabolic process	GO:0033238	20	0.950
regulation of cellular amino acid metabolic process	GO:0006521	5	0.884
regulation of renal output by angiotensin	GO:0002019	2	0.883	Mouse
kidney development	GO:0001822	213	0.856	Mouse
renal system development	GO:0072001	225	0.847	Mouse
defense response to bacterium	GO:0042742	119	0.824
urogenital system development	GO:0001655	261	0.818	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.810
regulation of systemic arterial blood pressure by circulatory renin angiotensin	GO:0001991	13	0.806	Mouse
cellular ketone metabolic process	GO:0042180	84	0.805
regionalization	GO:0003002	337	0.775
negative regulation of systemic arterial blood pressure	GO:0003085	15	0.765	Mouse
regulation of cytokine production	GO:0001817	266	0.755	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.751
regulation of leukocyte differentiation	GO:1902105	159	0.742
skeletal system development	GO:0001501	356	0.730
mesonephric tubule morphogenesis	GO:0072171	63	0.729	Mouse
intrinsic apoptotic signaling pathway in response to osmotic stress	GO:0008627	2	0.708
leukocyte differentiation	GO:0002521	342	0.668
nephron development	GO:0072006	109	0.649	Mouse
ureteric bud development	GO:0001657	94	0.620	Mouse
cytokine production	GO:0001816	319	0.612	Mouse
positive regulation of secretion	GO:0051047	130	0.612	Mouse
gland development	GO:0048732	330	0.603
mesonephric tubule development	GO:0072164	94	0.603	Mouse
gliogenesis	GO:0042063	141	0.597
t cell activation	GO:0042110	289	0.591
cellular amine metabolic process	GO:0044106	44	0.583
nephron epithelium morphogenesis	GO:0072088	68	0.571	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.565
organic hydroxy compound metabolic process	GO:1901615	203	0.559
kidney morphogenesis	GO:0060993	83	0.552	Mouse
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	GO:1902239	1	0.550
angiogenesis	GO:0001525	201	0.542
positive regulation of defense response	GO:0031349	124	0.534
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.530
peptidyl tyrosine phosphorylation	GO:0018108	143	0.530
regulation of kidney development	GO:0090183	40	0.528	Mouse
heart morphogenesis	GO:0003007	178	0.525
neuroepithelial cell differentiation	GO:0060563	37	0.522
extrinsic apoptotic signaling pathway	GO:0097191	126	0.519
endocrine system development	GO:0035270	98	0.516
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	GO:1990127	1	0.513
epithelial tube morphogenesis	GO:0060562	303	0.512	Mouse
response to organic cyclic compound	GO:0014070	198	0.509
epithelial cell development	GO:0002064	159	0.504
negative regulation of phosphate metabolic process	GO:0045936	184	0.500
diencephalon development	GO:0021536	63	0.497
response to molecule of bacterial origin	GO:0002237	143	0.497	Mouse
fat cell differentiation	GO:0045444	160	0.492
chemotaxis	GO:0006935	247	0.487
regulation of system process	GO:0044057	200	0.480	Mouse
central nervous system neuron differentiation	GO:0021953	162	0.479
forebrain cell migration	GO:0021885	58	0.476
morphogenesis of a branching epithelium	GO:0061138	193	0.474	Mouse
blood circulation	GO:0008015	195	0.463
cardiac muscle tissue development	GO:0048738	130	0.462
striated muscle tissue development	GO:0014706	293	0.455
positive regulation of cytokine production	GO:0001819	174	0.455	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.455
muscle system process	GO:0003012	141	0.442
regulation of ion transport	GO:0043269	215	0.434
regulation of lymphocyte activation	GO:0051249	240	0.430
spermatogenesis	GO:0007283	284	0.429
defense response to other organism	GO:0098542	197	0.429
negative regulation of cellular amine metabolic process	GO:0033239	1	0.429
glial cell development	GO:0021782	54	0.421
kidney epithelium development	GO:0072073	121	0.420	Mouse
negative regulation of smooth muscle cell apoptotic process	GO:0034392	1	0.419	Mouse
leukocyte mediated immunity	GO:0002443	174	0.418
positive regulation of voltage gated calcium channel activity	GO:1901387	2	0.418
cell chemotaxis	GO:0060326	81	0.414
metanephros development	GO:0001656	79	0.407	Mouse
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	GO:1902218	1	0.402
positive regulation of programmed cell death	GO:0043068	218	0.402
response to decreased oxygen levels	GO:0036293	59	0.400
response to lipopolysaccharide	GO:0032496	128	0.398	Mouse
positive regulation of apoptotic process	GO:0043065	217	0.396
regulation of cell motility	GO:2000145	236	0.391
dopamine metabolic process	GO:0042417	23	0.389
divalent metal ion transport	GO:0070838	172	0.386
negative regulation of intracellular signal transduction	GO:1902532	167	0.385
positive regulation of cell development	GO:0010720	237	0.383
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.380
telencephalon development	GO:0021537	186	0.374
blood vessel morphogenesis	GO:0048514	285	0.373
glial cell differentiation	GO:0010001	131	0.368
peptidyl amino acid modification	GO:0018193	336	0.366
protein secretion	GO:0009306	111	0.363	Mouse
peptidyl tyrosine modification	GO:0018212	145	0.362
regulation of cell migration	GO:0030334	219	0.362
forebrain development	GO:0030900	302	0.359
calcium ion transport	GO:0006816	159	0.358
regulation of secretion by cell	GO:1903530	249	0.357	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	5	0.356
circulatory system process	GO:0003013	197	0.355
ossification	GO:0001503	216	0.346
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.345
male gonad development	GO:0008584	88	0.329
peptide secretion	GO:0002790	114	0.326
regulation of ossification	GO:0030278	112	0.326
purine containing compound metabolic process	GO:0072521	311	0.325
regulation of metanephros development	GO:0072215	15	0.325	Mouse
alcohol metabolic process	GO:0006066	116	0.322
inflammatory response	GO:0006954	244	0.321	Mouse
axonogenesis	GO:0007409	274	0.320
axon guidance	GO:0007411	141	0.319
skeletal system morphogenesis	GO:0048705	203	0.319
limb development	GO:0060173	166	0.313
immune effector process	GO:0002252	321	0.310
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger	GO:0007199	1	0.309	Mouse
muscle contraction	GO:0006936	101	0.308
cellular lipid metabolic process	GO:0044255	323	0.296
t cell differentiation	GO:0030217	174	0.295
catecholamine metabolic process	GO:0006584	30	0.292
odontogenesis	GO:0042476	78	0.291
digestive system development	GO:0055123	200	0.286
metanephric nephron development	GO:0072210	34	0.283	Mouse
regulation of secretion	GO:0051046	274	0.280	Mouse
telencephalon cell migration	GO:0022029	55	0.280
regulation of hormone levels	GO:0010817	211	0.279
pituitary gland development	GO:0021983	38	0.275
bone morphogenesis	GO:0060349	78	0.274
small molecule biosynthetic process	GO:0044283	132	0.272
cellular response to organic cyclic compound	GO:0071407	87	0.270
response to growth factor	GO:0070848	198	0.269
adenohypophysis development	GO:0021984	14	0.268
negative regulation of protein metabolic process	GO:0051248	282	0.268
carbohydrate derivative biosynthetic process	GO:1901137	183	0.266
nephron epithelium development	GO:0072009	92	0.266	Mouse
limb morphogenesis	GO:0035108	149	0.264
regulation of defense response	GO:0031347	233	0.263
neuronal action potential	GO:0019228	54	0.263
regulation of organ morphogenesis	GO:2000027	144	0.263	Mouse
development of primary sexual characteristics	GO:0045137	143	0.262
biomineral tissue development	GO:0031214	64	0.250
male gamete generation	GO:0048232	285	0.250
humoral immune response	GO:0006959	57	0.244
cellular response to lipid	GO:0071396	145	0.243
response to extracellular stimulus	GO:0009991	127	0.243
mesonephros development	GO:0001823	97	0.242	Mouse
feeding behavior	GO:0007631	62	0.240	Mouse
regulation of blood pressure	GO:0008217	93	0.239	Mouse
negative regulation of protein modification process	GO:0031400	163	0.239
nephron tubule morphogenesis	GO:0072078	68	0.239	Mouse
regulation of membrane potential	GO:0042391	192	0.239
positive regulation of leukocyte proliferation	GO:0070665	73	0.233
regulation of heart contraction	GO:0008016	77	0.233	Mouse
intracellular protein transport	GO:0006886	204	0.233
mesenchymal cell differentiation	GO:0048762	107	0.232
male sex differentiation	GO:0046661	109	0.231
cell type specific apoptotic process	GO:0097285	268	0.227	Mouse
regulation of transferase activity	GO:0051338	263	0.226
embryonic skeletal system development	GO:0048706	120	0.226
extracellular matrix organization	GO:0030198	147	0.222
regulation of apoptotic signaling pathway	GO:2001233	197	0.222
regulation of systemic arterial blood pressure	GO:0003073	61	0.221	Mouse
cardiocyte differentiation	GO:0035051	87	0.220
negative regulation of phosphorus metabolic process	GO:0010563	184	0.219
cerebral cortex cell migration	GO:0021795	44	0.219
response to organonitrogen compound	GO:0010243	246	0.217
determination of left right symmetry	GO:0007368	80	0.216
myeloid leukocyte differentiation	GO:0002573	119	0.216
branching morphogenesis of an epithelial tube	GO:0048754	159	0.216	Mouse
ameboidal type cell migration	GO:0001667	128	0.210
cellular response to metal ion	GO:0071248	31	0.208
regulation of organ growth	GO:0046620	61	0.207
developmental maturation	GO:0021700	193	0.207
positive regulation of lymphocyte activation	GO:0051251	140	0.206
endocrine process	GO:0050886	39	0.206	Mouse
epithelial cell proliferation	GO:0050673	174	0.205
regulation of protein transport	GO:0051223	163	0.205	Mouse
apoptotic signaling pathway	GO:0097190	306	0.204
rhythmic process	GO:0048511	174	0.203
regulation of cardiac muscle tissue growth	GO:0055021	26	0.200
regulation of metal ion transport	GO:0010959	106	0.200
thyroid stimulating hormone secreting cell differentiation	GO:0060129	4	0.198
protein kinase c activating g protein coupled receptor signaling pathway	GO:0007205	4	0.198
regulation of protein kinase activity	GO:0045859	232	0.197
jak stat cascade	GO:0007259	42	0.196
mesenchyme development	GO:0060485	152	0.194
cellular chemical homeostasis	GO:0055082	215	0.194	Mouse
negative regulation of muscle contraction	GO:0045932	12	0.191
neuron death	GO:0070997	154	0.190
positive regulation of secretion by cell	GO:1903532	114	0.189	Mouse
cellular response to external stimulus	GO:0071496	88	0.189
respiratory tube development	GO:0030323	167	0.187
connective tissue development	GO:0061448	179	0.187
regulation of heart growth	GO:0060420	31	0.187
response to fibroblast growth factor	GO:0071774	47	0.186
negative regulation of cell activation	GO:0050866	111	0.186
negative regulation of t cell activation	GO:0050868	65	0.185
cytoplasmic transport	GO:0016482	234	0.185
renal system process involved in regulation of systemic arterial blood pressure	GO:0003071	15	0.185	Mouse
negative regulation of heart rate	GO:0010459	4	0.184	Mouse
lung morphogenesis	GO:0060425	50	0.184
smooth muscle contraction	GO:0006939	44	0.183
peptidyl serine phosphorylation	GO:0018105	74	0.183
positive regulation of growth	GO:0045927	104	0.183
mammary gland duct morphogenesis	GO:0060603	38	0.182
cell fate commitment	GO:0045165	210	0.182
regulation of anatomical structure size	GO:0090066	178	0.180
camera type eye development	GO:0043010	266	0.178
regulation of muscle contraction	GO:0006937	49	0.177
extracellular structure organization	GO:0043062	148	0.176
skin development	GO:0043588	220	0.175
lens development in camera type eye	GO:0002088	62	0.175
nitrogen compound transport	GO:0071705	271	0.174
regulation of metanephric glomerulus development	GO:0072298	5	0.174	Mouse
regulation of blood vessel size	GO:0050880	56	0.173
pallium development	GO:0021543	120	0.173
macromolecule catabolic process	GO:0009057	281	0.172
limbic system development	GO:0021761	72	0.172
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.169
digestive tract morphogenesis	GO:0048546	147	0.167
action potential	GO:0001508	78	0.166
lung alveolus development	GO:0048286	45	0.165
organic hydroxy compound biosynthetic process	GO:1901617	77	0.165
respiratory system development	GO:0060541	190	0.163
regulation of neuron differentiation	GO:0045664	281	0.162
steroid metabolic process	GO:0008202	119	0.162
cell adhesion	GO:0007155	329	0.161
embryonic organ morphogenesis	GO:0048562	276	0.161
regulation of lipid metabolic process	GO:0019216	118	0.161
chondrocyte differentiation	GO:0002062	72	0.157
cardiac muscle tissue growth	GO:0055017	37	0.156
positive regulation of mesonephros development	GO:0061213	20	0.156	Mouse
response to oxygen levels	GO:0070482	62	0.154
muscle cell apoptotic process	GO:0010657	18	0.154	Mouse
negative regulation of phosphorylation	GO:0042326	166	0.154
regulation of t cell activation	GO:0050863	170	0.154
multicellular organismal signaling	GO:0035637	91	0.152
innate immune response	GO:0045087	157	0.151
protein maturation	GO:0051604	176	0.150
positive regulation of protein modification process	GO:0031401	299	0.150
divalent inorganic cation transport	GO:0072511	178	0.149
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.149	Mouse
cellular response to inorganic substance	GO:0071241	37	0.148
alpha beta t cell differentiation	GO:0046632	69	0.148
astrocyte differentiation	GO:0048708	43	0.148
vascular process in circulatory system	GO:0003018	62	0.147
germ cell development	GO:0007281	185	0.145
bone development	GO:0060348	120	0.145
appendage morphogenesis	GO:0035107	149	0.145
neuron projection guidance	GO:0097485	141	0.145
regulation of kinase activity	GO:0043549	249	0.142
negative regulation of cellular protein metabolic process	GO:0032269	247	0.142
regulation of peptidyl serine phosphorylation	GO:0033135	39	0.141
regulation of systemic arterial blood pressure by hormone	GO:0001990	25	0.140	Mouse
regulation of epithelial cell proliferation	GO:0050678	141	0.138
lung development	GO:0030324	164	0.138
stem cell development	GO:0048864	219	0.137
regulation of cellular response to stress	GO:0080135	159	0.137
positive regulation of cytokine secretion	GO:0050715	41	0.136	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.136
sensory perception of pain	GO:0019233	47	0.135
sensory organ morphogenesis	GO:0090596	242	0.134
positive regulation of protein secretion	GO:0050714	52	0.132	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.132
peripheral nervous system development	GO:0007422	53	0.132
protein processing	GO:0016485	163	0.131
response to nutrient levels	GO:0031667	109	0.131
embryonic appendage morphogenesis	GO:0035113	126	0.131
lipid biosynthetic process	GO:0008610	179	0.131
heart process	GO:0003015	94	0.131	Mouse
metanephric glomerulus development	GO:0072224	13	0.130	Mouse
amine metabolic process	GO:0009308	45	0.129
leukocyte migration	GO:0050900	124	0.129	Mouse
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.126
positive regulation of cell activation	GO:0050867	158	0.122
phenol containing compound metabolic process	GO:0018958	60	0.122
positive regulation of nervous system development	GO:0051962	221	0.121
positive regulation of transcription via serum response element binding	GO:0010735	1	0.120
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway	GO:0051482	4	0.119	Mouse
regulation of peptide transport	GO:0090087	91	0.119
establishment of protein localization to organelle	GO:0072594	118	0.119
tissue migration	GO:0090130	68	0.119
renal tubule morphogenesis	GO:0061333	72	0.119	Mouse
positive regulation of cell death	GO:0010942	224	0.118
multicellular organism growth	GO:0035264	161	0.118
astrocyte fate commitment	GO:0060018	4	0.118
negative regulation of molecular function	GO:0044092	258	0.118
pigmentation	GO:0043473	71	0.117
regulation of blood volume by renin angiotensin	GO:0002016	7	0.116	Mouse
lymphocyte differentiation	GO:0030098	242	0.116
morphogenesis of a branching structure	GO:0001763	203	0.116	Mouse
positive regulation of leukocyte differentiation	GO:1902107	86	0.115
second messenger mediated signaling	GO:0019932	73	0.114
specification of organ identity	GO:0010092	30	0.114
adaptive immune response	GO:0002250	155	0.112
renal system process	GO:0003014	48	0.112	Mouse
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.112
positive regulation of metanephric glomerulus development	GO:0072300	4	0.112	Mouse
muscle cell differentiation	GO:0042692	261	0.112
forebrain generation of neurons	GO:0021872	63	0.111
purine ribonucleotide metabolic process	GO:0009150	290	0.110
cellular response to acid chemical	GO:0071229	68	0.110
axis elongation involved in somitogenesis	GO:0090245	4	0.108
response to metal ion	GO:0010038	47	0.108
regulation of cell division	GO:0051302	76	0.108
myeloid leukocyte mediated immunity	GO:0002444	42	0.108
somatotropin secreting cell differentiation	GO:0060126	4	0.107
epithelial cell migration	GO:0010631	63	0.107
positive regulation of epithelial cell proliferation	GO:0050679	68	0.107
regulation of sodium ion transport	GO:0002028	29	0.107
cardiac muscle cell differentiation	GO:0055007	69	0.107
branching involved in ureteric bud morphogenesis	GO:0001658	56	0.106	Mouse
cellular response to growth factor stimulus	GO:0071363	197	0.106
embryonic heart tube development	GO:0035050	65	0.105
renal tubule development	GO:0061326	87	0.105	Mouse
regulation of myeloid leukocyte differentiation	GO:0002761	58	0.105
regulation of cell cycle	GO:0051726	281	0.105
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.105	Mouse
pancreatic pp cell fate commitment	GO:0003329	2	0.104
hippocampus development	GO:0021766	52	0.104
regulation of carbohydrate metabolic process	GO:0006109	75	0.103
oxidation reduction process	GO:0055114	342	0.103	Mouse
cardiac chamber morphogenesis	GO:0003206	93	0.102
prostate gland morphogenesis	GO:0060512	32	0.102
lymphocyte mediated immunity	GO:0002449	139	0.101
positive regulation of stem cell proliferation	GO:2000648	59	0.100
tissue remodeling	GO:0048771	102	0.100
positive regulation of neuron differentiation	GO:0045666	141	0.100
purine containing compound biosynthetic process	GO:0072522	70	0.099
cell differentiation in spinal cord	GO:0021515	53	0.098
positive regulation of muscle tissue development	GO:1901863	32	0.098
appendage development	GO:0048736	166	0.098
neural tube patterning	GO:0021532	43	0.098
positive regulation of heart growth	GO:0060421	18	0.097
submandibular salivary gland formation	GO:0060661	1	0.097
mesonephric epithelium development	GO:0072163	94	0.097	Mouse
ensheathment of neurons	GO:0007272	76	0.097
regulation of innate immune response	GO:0045088	91	0.097
multicellular organismal response to stress	GO:0033555	62	0.096
amide transport	GO:0042886	138	0.095
negative regulation of prostatic bud formation	GO:0060686	4	0.095
development of primary male sexual characteristics	GO:0046546	88	0.095
positive regulation of angiogenesis	GO:0045766	46	0.095
mesenchymal cell development	GO:0014031	93	0.095
segmentation	GO:0035282	93	0.094
negative regulation of immune system process	GO:0002683	209	0.094
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.094
regulation of inflammatory response	GO:0050727	147	0.093
regulation of morphogenesis of a branching structure	GO:0060688	53	0.093	Mouse
maternal process involved in female pregnancy	GO:0060135	32	0.093
calcium mediated signaling	GO:0019722	46	0.093
apoptotic process involved in development	GO:1902742	28	0.093
hormone metabolic process	GO:0042445	86	0.093
transmission of nerve impulse	GO:0019226	76	0.093
negative regulation of neuron death	GO:1901215	98	0.093
organelle localization	GO:0051640	179	0.092
nucleobase containing small molecule metabolic process	GO:0055086	352	0.092
regulation of neuron projection development	GO:0010975	169	0.092
organophosphate biosynthetic process	GO:0090407	122	0.092
cartilage development	GO:0051216	140	0.091
spleen development	GO:0048536	39	0.091
regulation of voltage gated calcium channel activity	GO:1901385	4	0.089
regulation of blood circulation	GO:1903522	93	0.089	Mouse
regulation of cell growth	GO:0001558	91	0.089
fatty acid metabolic process	GO:0006631	121	0.089
regulation of stem cell proliferation	GO:0072091	78	0.089
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.089
regulation of muscle system process	GO:0090257	80	0.089
regulation of intracellular transport	GO:0032386	159	0.089
positive regulation of ossification	GO:0045778	47	0.088
b cell activation	GO:0042113	161	0.088
cellular amide metabolic process	GO:0043603	58	0.088
stem cell proliferation	GO:0072089	117	0.088
embryonic limb morphogenesis	GO:0030326	126	0.087
response to organophosphorus	GO:0046683	22	0.087
neural crest cell development	GO:0014032	48	0.087
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	45	0.086
regulation of protein localization	GO:0032880	231	0.086	Mouse
response to hypoxia	GO:0001666	58	0.086
regulation of ion transmembrane transport	GO:0034765	119	0.086
regulation of phospholipase a2 activity	GO:0032429	3	0.086
cation transport	GO:0006812	399	0.085
regulation of axon extension	GO:0030516	43	0.085
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.085
erk1 and erk2 cascade	GO:0070371	77	0.085
regulation of angiotensin levels in blood	GO:0002002	4	0.084
cellular homeostasis	GO:0019725	240	0.084	Mouse
cardiac chamber development	GO:0003205	108	0.083
positive regulation of fat cell proliferation	GO:0070346	1	0.083
developmental programmed cell death	GO:0010623	41	0.082
synaptic transmission	GO:0007268	329	0.082
organ growth	GO:0035265	117	0.082
heart growth	GO:0060419	45	0.082
neuron apoptotic process	GO:0051402	142	0.081
glycoprotein metabolic process	GO:0009100	116	0.081
cardiac pacemaker cell fate commitment	GO:0060927	1	0.081
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.081
paraxial mesodermal cell differentiation	GO:0048342	2	0.081
nucleotide biosynthetic process	GO:0009165	78	0.081
regulation of osteoblast differentiation	GO:0045667	67	0.081
regulation of glomerulus development	GO:0090192	6	0.080	Mouse
production of molecular mediator of immune response	GO:0002440	103	0.080
ras protein signal transduction	GO:0007265	77	0.080
monocarboxylic acid metabolic process	GO:0032787	191	0.080
myelination	GO:0042552	74	0.079
smoothened signaling pathway	GO:0007224	105	0.079
histone modification	GO:0016570	159	0.079
forebrain morphogenesis	GO:0048853	17	0.079
neural tube development	GO:0021915	160	0.078
odontogenesis of dentin containing tooth	GO:0042475	66	0.078
asymmetric stem cell division	GO:0098722	3	0.077
negative regulation of growth	GO:0045926	99	0.077
glandular epithelial cell differentiation	GO:0002067	38	0.077
negative regulation of lymphocyte activation	GO:0051250	91	0.077
endochondral bone morphogenesis	GO:0060350	50	0.076
muscle tissue development	GO:0060537	308	0.076
stem cell maintenance	GO:0019827	130	0.076
adult behavior	GO:0030534	135	0.075
regulation of cell activation	GO:0050865	289	0.075
metal ion homeostasis	GO:0055065	189	0.075	Mouse
bone remodeling	GO:0046849	53	0.075
regulation of tube size	GO:0035150	57	0.075
positive regulation of cardiac muscle tissue growth	GO:0055023	15	0.075
positive regulation of striated muscle tissue development	GO:0045844	31	0.075
cerebral cortex development	GO:0021987	86	0.075
endothelial cell proliferation	GO:0001935	27	0.075
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.075	Mouse
glycosyl compound metabolic process	GO:1901657	246	0.074
reactive oxygen species biosynthetic process	GO:1903409	8	0.074
salivary gland development	GO:0007431	37	0.074
response to calcium ion	GO:0051592	20	0.073
lung cell differentiation	GO:0060479	30	0.073
ribonucleotide metabolic process	GO:0009259	291	0.073
regulation of cardiac muscle cell proliferation	GO:0060043	23	0.073
organic cyclic compound catabolic process	GO:1901361	295	0.073
negative regulation of neuron differentiation	GO:0045665	101	0.072
pancreas development	GO:0031016	57	0.072
stem cell differentiation	GO:0048863	268	0.071
protein localization to organelle	GO:0033365	185	0.071
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure	GO:0002033	2	0.071	Mouse
collagen fibril organization	GO:0030199	32	0.071
lung epithelium development	GO:0060428	37	0.070
multicellular organismal metabolic process	GO:0044236	28	0.070
regulation of smoothened signaling pathway	GO:0008589	58	0.070
regulation of hydrolase activity	GO:0051336	246	0.070
mesenchymal cell proliferation	GO:0010463	44	0.070
ear development	GO:0043583	200	0.069
phospholipase c activating angiotensin activated signaling pathway	GO:0086097	1	0.069	Mouse
cellular response to abiotic stimulus	GO:0071214	56	0.068
paramesonephric duct development	GO:0061205	3	0.068
digestive tract development	GO:0048565	190	0.068
corticotropin hormone secreting cell differentiation	GO:0060128	3	0.068
placenta development	GO:0001890	140	0.068
exploration behavior	GO:0035640	21	0.068	Mouse
cellular calcium ion homeostasis	GO:0006874	119	0.067	Mouse
non canonical wnt signaling pathway via jnk cascade	GO:0038031	3	0.067
regulation of angiotensin metabolic process	GO:0060177	4	0.067
positive regulation of immune effector process	GO:0002699	107	0.067
regulation of white fat cell proliferation	GO:0070350	2	0.067
response to drug	GO:0042493	75	0.066
regulation of histone modification	GO:0031056	56	0.066
positive regulation of t cell activation	GO:0050870	101	0.066
regulation of cardiac muscle tissue development	GO:0055024	31	0.066
nephron tubule development	GO:0072080	84	0.066	Mouse
positive regulation of endothelial cell proliferation	GO:0001938	17	0.066
epithelium migration	GO:0090132	63	0.066
negative regulation of protein phosphorylation	GO:0001933	126	0.066
regulation of smooth muscle contraction	GO:0006940	22	0.066
regulation of lymphocyte differentiation	GO:0045619	107	0.065
mesoderm morphogenesis	GO:0048332	64	0.065
cell cell signaling involved in cell fate commitment	GO:0045168	35	0.065
planar cell polarity pathway involved in pericardium morphogenesis	GO:0061354	2	0.065
cytokine secretion	GO:0050663	72	0.065	Mouse
positive regulation of lymphocyte proliferation	GO:0050671	70	0.065
lung induction	GO:0060492	3	0.064
metanephros morphogenesis	GO:0003338	24	0.064	Mouse
leukocyte activation involved in immune response	GO:0002366	126	0.064
response to amphetamine	GO:0001975	16	0.064
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.064
axon ensheathment	GO:0008366	76	0.064
cardiac muscle cell proliferation	GO:0060038	31	0.064
negative regulation of cell development	GO:0010721	169	0.064
atrioventricular node cell fate commitment	GO:0060929	1	0.064
somatotropin secreting cell development	GO:0060133	2	0.064
ear morphogenesis	GO:0042471	118	0.064
muscle cell development	GO:0055001	133	0.063
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.063
heart trabecula formation	GO:0060347	14	0.063
positive regulation of epithelial cell proliferation involved in lung morphogenesis	GO:0060501	3	0.063
blood vessel remodeling	GO:0001974	33	0.063
cerebellum morphogenesis	GO:0021587	42	0.063
negative regulation of leukocyte differentiation	GO:1902106	51	0.063
hypophysis morphogenesis	GO:0048850	3	0.063
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.063
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.062	Mouse
phospholipase c activating g protein coupled receptor signaling pathway	GO:0007200	26	0.062	Mouse
regulation of peptide secretion	GO:0002791	77	0.061
cellular response to cytokine stimulus	GO:0071345	189	0.061
lung field specification	GO:0060424	3	0.061
morphogenesis of embryonic epithelium	GO:0016331	159	0.061

Bdkrb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of metabolism	DOID:0014667	0	0.086

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