Mus musculus

31 known processes

Rgn

regucalcin

(Aliases: SMP30,AI265316,GNL)

Rgn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monocarboxylic acid metabolic processGO:00327871910.233
cellular amino acid metabolic processGO:00065201030.205
oxidation reduction processGO:00551143420.193
organic hydroxy compound metabolic processGO:19016152030.192
carbohydrate metabolic processGO:00059752300.185
steroid metabolic processGO:00082021190.170
small molecule catabolic processGO:0044282710.169
sterol metabolic processGO:0016125580.151
fatty acid metabolic processGO:00066311210.146
cellular ketone metabolic processGO:0042180840.144
lipid biosynthetic processGO:00086101790.139
cellular lipid metabolic processGO:00442553230.130
small molecule biosynthetic processGO:00442831320.127
protein maturationGO:00516041760.114
negative regulation of molecular functionGO:00440922580.101
response to organic cyclic compoundGO:00140701980.098
regulation of hormone levelsGO:00108172110.094
neutral lipid metabolic processGO:0006638570.093
lipid catabolic processGO:0016042690.092
regulation of hydrolase activityGO:00513362460.089
fibrinolysisGO:004273030.086
cholesterol metabolic processGO:0008203560.086
male gamete generationGO:00482322850.083
cellular amine metabolic processGO:0044106440.083
alcohol metabolic processGO:00060661160.073
amine metabolic processGO:0009308450.073
kidney epithelium developmentGO:00720731210.068
regulation of body fluid levelsGO:00508781620.067
hormone metabolic processGO:0042445860.067
regulation of cellular ketone metabolic processGO:0010565660.066
monocarboxylic acid biosynthetic processGO:0072330610.066
cellular response to lipidGO:00713961450.065
monosaccharide metabolic processGO:00059961060.064
ion transmembrane transportGO:00342203610.061
negative regulation of protein metabolic processGO:00512482820.058
negative regulation of hydrolase activityGO:0051346710.058
cell adhesionGO:00071553290.058
toxin catabolic processGO:000940710.056
sulfur compound metabolic processGO:00067901000.055
skeletal system developmentGO:00015013560.055
regulation of secretionGO:00510462740.053
spermatogenesisGO:00072832840.052
extracellular structure organizationGO:00430621480.052
aspartate family amino acid metabolic processGO:0009066100.051
cellular lipid catabolic processGO:0044242520.051
nitrogen compound transportGO:00717052710.050
negative regulation of cell proliferationGO:00082852960.050
lipid localizationGO:00108761260.049
regulation of cellular amine metabolic processGO:0033238200.049
organic acid catabolic processGO:0016054510.049
response to organonitrogen compoundGO:00102432460.049
establishment of blood nerve barrierGO:000806530.048
very long chain fatty acid catabolic processGO:004276020.048
regulation of mapk cascadeGO:00434082480.048
cell type specific apoptotic processGO:00972852680.047
carboxylic acid biosynthetic processGO:0046394860.047
response to inorganic substanceGO:0010035960.046
glycerolipid metabolic processGO:00464861220.045
negative regulation of cellular protein metabolic processGO:00322692470.045
inorganic ion transmembrane transportGO:00986602340.045
morphogenesis of a branching epitheliumGO:00611381930.045
organic acid biosynthetic processGO:0016053860.044
rhythmic processGO:00485111740.044
oxidative demethylationGO:007098910.044
response to acid chemicalGO:00011011110.043
cellular modified amino acid metabolic processGO:0006575630.043
positive regulation of protein phosphorylationGO:00019342420.043
gland developmentGO:00487323300.042
protein processingGO:00164851630.042
response to testosteroneGO:003357430.042
carboxylic acid catabolic processGO:0046395510.041
regulation of protein maturationGO:1903317960.041
cellular alcohol metabolic processGO:004410730.040
liver developmentGO:0001889660.040
renal system developmentGO:00720012250.040
cofactor transportGO:005118140.039
negative regulation of proteolysisGO:0045861740.039
negative regulation of serine type endopeptidase activityGO:190000420.039
muscle tissue developmentGO:00605373080.039
regulation of cellular amino acid metabolic processGO:000652150.038
reactive oxygen species metabolic processGO:0072593840.038
regulation of membrane potentialGO:00423911920.038
regulation of proteolysisGO:00301621640.038
steroid biosynthetic processGO:0006694470.038
cytokine productionGO:00018163190.037
negative regulation of protein processingGO:0010955790.037
transmembrane transportGO:00550854120.037
positive regulation of apoptotic processGO:00430652170.036
organic hydroxy compound transportGO:0015850930.036
regulation of cellular catabolic processGO:00313292420.036
cholesterol homeostasisGO:0042632440.036
nucleobase containing small molecule metabolic processGO:00550863520.035
regulation of lipid metabolic processGO:00192161180.035
vitamin metabolic processGO:0006766230.034
regulation of transferase activityGO:00513382630.034
fatty acid biosynthetic processGO:0006633410.034
cellular response to organonitrogen compoundGO:00714171450.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
blood vessel morphogenesisGO:00485142850.033
urogenital system developmentGO:00016552610.033
organic hydroxy compound biosynthetic processGO:1901617770.032
fertilizationGO:00095661270.032
epithelial cell proliferationGO:00506731740.032
regulation of glucose metabolic processGO:0010906600.032
cellular homeostasisGO:00197252400.031
regulation of kinase activityGO:00435492490.031
striated muscle tissue developmentGO:00147062930.031
regulation of protein localizationGO:00328802310.031
response to peptide hormoneGO:00434341270.031
hepaticobiliary system developmentGO:0061008670.030
regulation of renal sodium excretionGO:003581330.030
acylglycerol metabolic processGO:0006639550.030
glucose metabolic processGO:0006006920.030
regulation of reactive oxygen species metabolic processGO:2000377400.030
cation transportGO:00068123990.030
alpha amino acid metabolic processGO:1901605590.030
negative regulation of fibrinolysisGO:005191810.030
regulation of homeostatic processGO:00328441820.030
circulatory system processGO:00030131970.030
apoptotic signaling pathwayGO:00971903060.029
blood circulationGO:00080151950.029
amino acid transmembrane transportGO:0003333370.029
regulation of secretion by cellGO:19035302490.029
organic cyclic compound catabolic processGO:19013612950.029
progesterone metabolic processGO:004244840.029
sulfate assimilationGO:000010330.029
positive regulation of protein serine threonine kinase activityGO:00719021060.028
response to chromateGO:004668710.028
connective tissue developmentGO:00614481790.028
regulation of organ morphogenesisGO:20000271440.027
positive regulation of insulin receptor signaling pathwayGO:004662840.027
extracellular matrix organizationGO:00301981470.027
cellular response to hormone stimulusGO:00328701500.027
negative regulation of immune system processGO:00026832090.027
nephron developmentGO:00720061090.026
organonitrogen compound catabolic processGO:19015652640.026
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.026
morphogenesis of a branching structureGO:00017632030.026
regulation of peptidase activityGO:0052547960.026
locomotory behaviorGO:00076261950.026
single fertilizationGO:0007338820.026
reactive oxygen species biosynthetic processGO:190340980.025
purine containing compound metabolic processGO:00725213110.025
regulation of cell activationGO:00508652890.025
regulation of protein kinase activityGO:00458592320.025
development of primary female sexual characteristicsGO:0046545730.025
regulation of protein processingGO:0070613960.025
cellular nitrogen compound catabolic processGO:00442702800.025
carnitine transmembrane transportGO:190260330.025
lipid transportGO:0006869980.025
heterocycle catabolic processGO:00467002800.025
negative regulation of protein maturationGO:1903318790.024
response to nutrient levelsGO:00316671090.024
carnitine transportGO:001587930.024
striated muscle myosin thick filament assemblyGO:007168810.024
terpenoid metabolic processGO:0006721250.024
male sex differentiationGO:00466611090.024
inflammatory responseGO:00069542440.024
renal system processGO:0003014480.024
monocarboxylic acid catabolic processGO:0072329270.024
response to steroid hormoneGO:0048545560.023
negative regulation of endopeptidase activityGO:0010951440.023
sensory organ morphogenesisGO:00905962420.023
long chain fatty acid importGO:004453920.023
multicellular organismal homeostasisGO:00488711640.023
mapk cascadeGO:00001652810.023
cofactor metabolic processGO:0051186800.023
regulation of protein serine threonine kinase activityGO:00719001570.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.023
embryonic placenta developmentGO:0001892980.023
lymphocyte differentiationGO:00300982420.023
anion transmembrane transportGO:0098656710.023
amino acid betaine transportGO:001583830.022
anion transportGO:00068201770.022
epithelial cell developmentGO:00020641590.022
developmental maturationGO:00217001930.022
positive regulation of cell deathGO:00109422240.022
myeloid cell differentiationGO:00300992330.022
carbohydrate homeostasisGO:00335001280.022
female sex differentiationGO:0046660840.022
regulation of response to woundingGO:19030341890.021
regulation of plasminogen activationGO:001075540.021
leukocyte differentiationGO:00025213420.021
regulation of system processGO:00440572000.021
regulation of vesicle mediated transportGO:00606271390.021
vitamin d biosynthetic processGO:004236830.021
kidney developmentGO:00018222130.021
response to monosaccharideGO:0034284670.021
hexose metabolic processGO:0019318980.021
cellular response to organic cyclic compoundGO:0071407870.021
nucleotide metabolic processGO:00091173320.021
camera type eye developmentGO:00430102660.021
cell maturationGO:00484691270.021
regulation of epithelial cell proliferationGO:00506781410.021
positive regulation of protein modification processGO:00314012990.021
mitochondrion organizationGO:00070051340.020
xenobiotic catabolic processGO:004217810.020
response to peptideGO:19016521360.020
regulation of defense responseGO:00313472330.020
female gonad developmentGO:0008585710.020
short chain fatty acid catabolic processGO:001962620.020
lipid homeostasisGO:0055088630.020
regulation of serine type endopeptidase activityGO:190000320.020
reactive nitrogen species metabolic processGO:200105700.020
nephron tubule morphogenesisGO:0072078680.020
alcohol biosynthetic processGO:0046165430.020
spermatid differentiationGO:00485151150.020
amide transportGO:00428861380.020
organic acid transportGO:00158491010.020
adiponectin activated signaling pathwayGO:003321140.020
skeletal muscle organ developmentGO:00605381630.020
development of primary sexual characteristicsGO:00451371430.020
cellular response to hexose stimulusGO:0071331470.019
neuron deathGO:00709971540.019
coenzyme metabolic processGO:0006732520.019
macromolecule catabolic processGO:00090572810.019
protein catabolic processGO:00301632210.019
negative regulation of peptidase activityGO:0010466460.019
negative regulation of lipid metabolic processGO:0045833300.019
nucleoside phosphate metabolic processGO:00067533380.019
regulation of cellular response to stressGO:00801351590.019
ventricular cardiac muscle cell action potentialGO:008600540.019
homeostasis of number of cellsGO:00488722100.019
renal tubule developmentGO:0061326870.019
nucleoside catabolic processGO:00091642060.019
monocarboxylic acid transportGO:0015718440.019
regulation of peptide transportGO:0090087910.018
cellular alcohol biosynthetic processGO:004410830.018
cholesterol transportGO:0030301380.018
response to oxygen levelsGO:0070482620.018
folic acid containing compound metabolic processGO:000676030.018
positive regulation of protein kinase activityGO:00458601440.018
ribose phosphate metabolic processGO:00196932910.018
organ growthGO:00352651170.018
histamine uptakeGO:005161510.018
protein modification by small protein conjugation or removalGO:00706472070.018
response to oxidative stressGO:00069791230.018
nephron epithelium developmentGO:0072009920.018
nephron tubule developmentGO:0072080840.018
peptide transportGO:00158331330.018
response to iron ionGO:001003940.018
endothelial cell differentiationGO:0045446410.018
positive regulation of transferase activityGO:00513471670.018
regulation of blood vessel sizeGO:0050880560.018
metal ion homeostasisGO:00550651890.018
regulation of inflammatory responseGO:00507271470.018
multicellular organism growthGO:00352641610.018
organic anion transportGO:00157111370.018
protein activation cascadeGO:0072376190.017
multicellular organismal signalingGO:0035637910.017
purine nucleoside metabolic processGO:00422782410.017
activation of immune responseGO:00022531380.017
glycosyl compound metabolic processGO:19016572460.017
anatomical structure homeostasisGO:00602491450.017
mesonephric tubule morphogenesisGO:0072171630.017
divalent inorganic cation transportGO:00725111780.017
positive regulation of plasminogen activationGO:001075620.017
cellular response to insulin stimulusGO:0032869780.017
organ regenerationGO:003110020.017
cellular carbohydrate metabolic processGO:00442621190.017
regionalizationGO:00030023370.017
maintenance of locationGO:0051235890.017
fat soluble vitamin metabolic processGO:0006775110.017
cellular chemical homeostasisGO:00550822150.017
negative regulation of response to woundingGO:1903035770.016
porphyrin containing compound metabolic processGO:0006778220.016
regulation of fatty acid metabolic processGO:0019217280.016
positive regulation of cellular amine metabolic processGO:003324050.016
branching morphogenesis of an epithelial tubeGO:00487541590.016
bone remodelingGO:0046849530.016
cellular response to inorganic substanceGO:0071241370.016
cellular amino acid catabolic processGO:0009063250.016
kidney morphogenesisGO:0060993830.016
meiotic cell cycleGO:00513211220.016
myosin filament assemblyGO:003103420.016
retinoid metabolic processGO:0001523240.016
cellular response to cadmium ionGO:007127630.016
regulation of tissue remodelingGO:0034103380.016
wound healingGO:00420601570.016
regulation of fibrinolysisGO:005191710.016
respiratory tube developmentGO:00303231670.016
cellular response to cytokine stimulusGO:00713451890.016
positive regulation of reactive oxygen species metabolic processGO:2000379110.016
dna metabolic processGO:00062593030.016
protein secretionGO:00093061110.016
cation transmembrane transportGO:00986552660.016
positive regulation of fatty acid biosynthetic processGO:004572330.016
ribonucleoside triphosphate metabolic processGO:00091992200.016
actin cytoskeleton organizationGO:00300362200.016
regulation of neurotransmitter levelsGO:0001505870.016
organelle fissionGO:00482851700.016
purine nucleotide metabolic processGO:00061633020.016
respiratory system developmentGO:00605411900.016
fat soluble vitamin biosynthetic processGO:004236240.015
cellular amide metabolic processGO:0043603580.015
endocytosisGO:00068971680.015
regulation of neuron differentiationGO:00456642810.015
regulation of establishment of protein localizationGO:00702011810.015
regulation of cell projection organizationGO:00313442060.015
learning or memoryGO:00076111480.015
negative regulation of phosphate metabolic processGO:00459361840.015
positive regulation of fatty acid oxidationGO:004632140.015
purine ribonucleoside catabolic processGO:00461302050.015
cardiac muscle tissue developmentGO:00487381300.015
placenta developmentGO:00018901400.015
testosterone biosynthetic processGO:006137020.015
posttranscriptional regulation of gene expressionGO:00106081550.015
cellular protein complex assemblyGO:00436231160.015
nucleotide catabolic processGO:00091662170.015
ribonucleoside metabolic processGO:00091192450.015
response to phenylpropanoidGO:0080184220.015
glucose homeostasisGO:00425931280.015
nephron morphogenesisGO:0072028690.015
nucleoside metabolic processGO:00091162460.015
nuclear divisionGO:00002801580.015
purine ribonucleotide metabolic processGO:00091502900.015
organophosphate catabolic processGO:00464342320.015
cation homeostasisGO:00550802120.015
organelle assemblyGO:00709251770.015
positive regulation of mapk cascadeGO:00434101700.015
cellular response to acid chemicalGO:0071229680.015
response to starvationGO:0042594650.015
multi multicellular organism processGO:00447061090.015
regulation of cell cycleGO:00517262810.015
vitamin d3 metabolic processGO:007064030.015
regulation of interleukin 8 secretionGO:200048220.015
interleukin 8 productionGO:003263740.015
cellular response to peptide hormone stimulusGO:0071375920.015
interleukin 8 secretionGO:007260630.015
sensory perceptionGO:00076002450.015
response to molecule of bacterial originGO:00022371430.015
cellular response to carbohydrate stimulusGO:0071322500.015
ribonucleotide metabolic processGO:00092592910.015
hematopoietic progenitor cell differentiationGO:00022441430.015
regulation of cell motilityGO:20001452360.014
maternal process involved in female pregnancyGO:0060135320.014
regulation of carbohydrate metabolic processGO:0006109750.014
regulation of lipoprotein lipase activityGO:005100440.014
rna processingGO:00063961050.014
regulation of transmembrane transportGO:00347621280.014
positive regulation of defense responseGO:00313491240.014
hormone secretionGO:00468791280.014
negative regulation of intracellular signal transductionGO:19025321670.014
negative regulation of neuron deathGO:1901215980.014
epithelial tube morphogenesisGO:00605623030.014
regulation of ion transmembrane transportGO:00347651190.014
cellular response to peptideGO:1901653920.014
negative regulation of cellular component organizationGO:00511291940.014
cellular response to oxidative stressGO:0034599760.014
response to hypoxiaGO:0001666580.014
negative regulation of nervous system developmentGO:00519611560.014
regulation of ion transportGO:00432692150.014
diterpenoid metabolic processGO:0016101240.014
muscle contractionGO:00069361010.014
response to extracellular stimulusGO:00099911270.014
regulation of interleukin 8 productionGO:003267730.014
unsaturated fatty acid metabolic processGO:0033559310.014
mitotic cell cycleGO:00002781950.014
purine ribonucleoside metabolic processGO:00461282410.014
regulation of gluconeogenesisGO:0006111300.014
female meiosis chromosome segregationGO:001632110.014
positive regulation of map kinase activityGO:0043406840.014
regulation of wound healingGO:0061041400.014
male gonad developmentGO:0008584880.014
secondary metabolite catabolic processGO:009048710.014
triglyceride metabolic processGO:0006641510.013
negative regulation of neuron apoptotic processGO:0043524920.013
positive regulation of growthGO:00459271040.013
intrinsic apoptotic signaling pathwayGO:00971931320.013
regulation of steroid metabolic processGO:0019218390.013
endothelium developmentGO:0003158450.013
renal tubule morphogenesisGO:0061333720.013
regulation of organelle organizationGO:00330432890.013
cellular response to starvationGO:0009267570.013
nucleoside triphosphate metabolic processGO:00091412300.013
renal sodium excretionGO:003581230.013
positive regulation of lipid metabolic processGO:0045834400.013
negative regulation of growthGO:0045926990.013
circadian regulation of gene expressionGO:0032922480.013
regulation of blood coagulationGO:0030193280.013
methylationGO:00322591340.013
regulation of apoptotic signaling pathwayGO:20012331970.013
regulation of heart contractionGO:0008016770.013
myosin filament organizationGO:003103330.013
cellular macromolecule catabolic processGO:00442652060.013
regulation of renal output by angiotensinGO:000201920.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.013
regulation of cellular carbohydrate metabolic processGO:0010675750.013
zymogen activationGO:0031638410.013
ureteric bud developmentGO:0001657940.013
cellular biogenic amine metabolic processGO:0006576280.013
vascular process in circulatory systemGO:0003018620.013
mesonephros developmentGO:0001823970.013
chromatin organizationGO:00063252060.013
response to metal ionGO:0010038470.013
positive regulation of kinase activityGO:00336741550.013
organophosphate biosynthetic processGO:00904071220.013
alpha amino acid biosynthetic processGO:1901607150.012
activation of mapk activityGO:0000187590.012
regulation of mitotic cell cycleGO:00073461260.012
negative regulation of apoptotic signaling pathwayGO:20012341040.012
secondary alcohol metabolic processGO:190265230.012
binding of sperm to zona pellucidaGO:0007339340.012
cellular response to molecule of bacterial originGO:0071219830.012
amino acid betaine metabolic processGO:000657770.012
fat cell differentiationGO:00454441600.012
regulation of blood pressureGO:0008217930.012
peptide hormone secretionGO:00300721090.012
cellular ion homeostasisGO:00068731650.012
innate immune responseGO:00450871570.012
response to drugGO:0042493750.012
divalent inorganic cation homeostasisGO:00725071380.012
protein oligomerizationGO:0051259670.012
negative regulation of epithelial cell proliferationGO:0050680640.012
aromatic compound catabolic processGO:00194392860.012
glutathione metabolic processGO:0006749160.012
peptidyl amino acid modificationGO:00181933360.012
fatty acid catabolic processGO:0009062250.012
ovulation cycleGO:0042698590.012
regulation of carbohydrate biosynthetic processGO:0043255400.012
insulin secretionGO:0030073890.012
membrane organizationGO:00610242450.012
mrna metabolic processGO:0016071840.012
purine nucleoside monophosphate metabolic processGO:0009126810.012
heart growthGO:0060419450.012
cellular response to biotic stimulusGO:0071216920.012
response to corticosteroneGO:005141210.012
inorganic cation transmembrane transportGO:00986622070.012
regulation of peptide secretionGO:0002791770.012
ketone body biosynthetic processGO:004695110.012
regulation of map kinase activityGO:00434051200.012
heme transportGO:001588620.012
positive regulation of nervous system developmentGO:00519622210.012
medium chain fatty acid metabolic processGO:005179110.012
heart morphogenesisGO:00030071780.012
regulation of cell adhesionGO:00301551540.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
myeloid leukocyte differentiationGO:00025731190.012
embryonic organ morphogenesisGO:00485622760.012
negative regulation of phosphorylationGO:00423261660.012
divalent metal ion transportGO:00708381720.012
hindbrain developmentGO:00309021280.011
regulation of cytokine productionGO:00018172660.011
female gamete generationGO:0007292740.011
response to lipopolysaccharideGO:00324961280.011
iron coordination entity transportGO:190167850.011
protein glycosylationGO:0006486550.011
negative regulation of lipoprotein lipase activityGO:005100510.011
neuron apoptotic processGO:00514021420.011
regulation of neuron deathGO:19012141340.011
rho protein signal transductionGO:0007266320.011
spermatid developmentGO:00072861080.011
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.011
ureteric bud morphogenesisGO:0060675620.011
positive regulation of cell developmentGO:00107202370.011
regulation of leukocyte differentiationGO:19021051590.011
negative regulation of cell cycleGO:00457861230.011
regulation of systemic arterial blood pressureGO:0003073610.011
ketone body metabolic processGO:190222430.011
complement activationGO:0006956160.011
purine containing compound catabolic processGO:00725232130.011
androgen biosynthetic processGO:000670240.011
purine nucleotide catabolic processGO:00061952110.011
response to temperature stimulusGO:0009266550.011
ribonucleotide catabolic processGO:00092612080.011
regulation of purine nucleotide metabolic processGO:19005421690.011
protein homooligomerizationGO:0051260430.011
smad protein signal transductionGO:0060395210.011
symbiosis encompassing mutualism through parasitismGO:0044403830.011
sodium ion transmembrane transportGO:0035725490.011
regulation of endopeptidase activityGO:0052548890.011
cellular divalent inorganic cation homeostasisGO:00725031270.011
phospholipid metabolic processGO:0006644870.011
cellular divalent inorganic anion homeostasisGO:007250130.011
lung developmentGO:00303241640.011
neuromuscular processGO:0050905990.011

Rgn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.121
inherited metabolic disorderDOID:65500.059
disease of anatomical entityDOID:700.038
cardiovascular system diseaseDOID:128700.038
immune system diseaseDOID:291400.023
nervous system diseaseDOID:86300.017
hematopoietic system diseaseDOID:7400.016
acquired metabolic diseaseDOID:006015800.015
alpha 1 antitrypsin deficiencyDOID:1337200.014
plasma protein metabolism diseaseDOID:234500.014
primary immunodeficiency diseaseDOID:61200.013
anemiaDOID:235500.013
vascular diseaseDOID:17800.013
hemolytic uremic syndromeDOID:1255400.012
hemolytic anemiaDOID:58300.012
normocytic anemiaDOID:72000.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011