Mus musculus

52 known processes

Sdc2

syndecan 2

(Aliases: Hspg1,syndecan-2,Synd2,4833414L08Rik,AA960457)

Sdc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to growth factorGO:00708481980.242
negative regulation of cell proliferationGO:00082852960.175
positive regulation of cellular amine metabolic processGO:003324050.127
regulation of cellular response to growth factor stimulusGO:0090287820.113
regulation of cellular amino acid metabolic processGO:000652150.100
positive regulation of nervous system developmentGO:00519622210.092
single organismal cell cell adhesionGO:00163371310.089
cellular amino acid metabolic processGO:00065201030.088
regulation of cell adhesionGO:00301551540.085
regulation of cellular ketone metabolic processGO:0010565660.084
ras protein signal transductionGO:0007265770.083
cellular amine metabolic processGO:0044106440.081
positive regulation of cellular amino acid metabolic processGO:004576430.081
cell adhesionGO:00071553290.078
actin cytoskeleton organizationGO:00300362200.073
regulation of cell migrationGO:00303342190.072
skeletal system developmentGO:00015013560.071
regulation of cell projection organizationGO:00313442060.071
negative regulation of cellular response to growth factor stimulusGO:0090288460.070
small gtpase mediated signal transductionGO:0007264970.068
amine metabolic processGO:0009308450.062
extracellular matrix organizationGO:00301981470.061
response to transforming growth factor betaGO:0071559880.060
macromolecule catabolic processGO:00090572810.058
cellular ketone metabolic processGO:0042180840.057
regulation of epithelial cell proliferationGO:00506781410.055
chemotaxisGO:00069352470.054
transforming growth factor beta receptor signaling pathwayGO:0007179710.054
regulation of mapk cascadeGO:00434082480.054
blood circulationGO:00080151950.053
wnt signaling pathwayGO:00160551880.053
Mouse
mapk cascadeGO:00001652810.052
nucleoside phosphate metabolic processGO:00067533380.052
regulation of peptidase activityGO:0052547960.051
camera type eye developmentGO:00430102660.051
purine nucleotide metabolic processGO:00061633020.051
single organism cell adhesionGO:00986021560.051
positive regulation of cell migrationGO:00303351090.050
protein processingGO:00164851630.049
regulation of cell motilityGO:20001452360.048
angiogenesisGO:00015252010.047
rho protein signal transductionGO:0007266320.047
negative regulation of protein metabolic processGO:00512482820.046
cytoplasmic transportGO:00164822340.045
cellular component assembly involved in morphogenesisGO:00109271390.045
protein maturationGO:00516041760.045
immune effector processGO:00022523210.043
regulation of endopeptidase activityGO:0052548890.043
regulation of intracellular transportGO:00323861590.043
regulation of cellular amine metabolic processGO:0033238200.043
cell substrate adhesionGO:00315891300.042
negative regulation of epithelial cell proliferationGO:0050680640.042
ribose phosphate metabolic processGO:00196932910.042
cell junction organizationGO:0034330770.041
inflammatory responseGO:00069542440.041
regulation of cytokine productionGO:00018172660.041
nucleobase containing small molecule metabolic processGO:00550863520.041
peptidyl amino acid modificationGO:00181933360.040
positive regulation of cell motilityGO:20001471160.040
positive regulation of cell developmentGO:00107202370.040
heart morphogenesisGO:00030071780.039
negative regulation of cellular protein metabolic processGO:00322692470.039
cell cell junction organizationGO:0045216720.039
sensory perceptionGO:00076002450.039
negative regulation of cell cycleGO:00457861230.039
nucleotide metabolic processGO:00091173320.038
negative regulation of phosphorus metabolic processGO:00105631840.038
negative regulation of blood vessel morphogenesisGO:2000181250.038
gastrulationGO:00073691160.037
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.037
glial cell differentiationGO:00100011310.036
negative regulation of complement activationGO:004591630.036
negative regulation of protein activation cascadeGO:200025830.035
positive regulation of cell projection organizationGO:0031346950.035
cytokine productionGO:00018163190.034
purine ribonucleotide metabolic processGO:00091502900.034
negative regulation of molecular functionGO:00440922580.034
regulation of hydrolase activityGO:00513362460.034
regulation of apoptotic signaling pathwayGO:20012331970.034
regulation of neuron differentiationGO:00456642810.034
developmental cell growthGO:0048588840.034
blood vessel morphogenesisGO:00485142850.032
regulation of proteolysisGO:00301621640.032
sensory organ morphogenesisGO:00905962420.032
forebrain developmentGO:00309003020.031
cellular response to growth factor stimulusGO:00713631970.031
extrinsic apoptotic signaling pathwayGO:00971911260.031
dephosphorylationGO:00163111290.031
extracellular structure organizationGO:00430621480.031
negative regulation of proteolysisGO:0045861740.030
sulfur compound metabolic processGO:00067901000.029
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.029
membrane organizationGO:00610242450.029
negative regulation of protein processingGO:0010955790.029
gland developmentGO:00487323300.028
ear developmentGO:00435832000.028
leukocyte proliferationGO:00706611720.028
regulation of cellular catabolic processGO:00313292420.028
aromatic compound catabolic processGO:00194392860.028
defense response to other organismGO:00985421970.027
urogenital system developmentGO:00016552610.027
positive regulation of protein kinase activityGO:00458601440.027
homotypic cell cell adhesionGO:0034109280.027
positive regulation of transferase activityGO:00513471670.027
regulation of cell morphogenesis involved in differentiationGO:00107691510.027
protein catabolic processGO:00301632210.026
positive regulation of mapk cascadeGO:00434101700.026
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.026
regulation of organelle organizationGO:00330432890.026
peptidyl tyrosine phosphorylationGO:00181081430.026
regulation of mitotic cell cycleGO:00073461260.026
digestive tract morphogenesisGO:00485461470.026
regulation of protein maturationGO:1903317960.026
regulation of ketone biosynthetic processGO:001056620.026
regulation of vasculature developmentGO:1901342880.026
regulation of protein processingGO:0070613960.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.025
spermatogenesisGO:00072832840.025
positive regulation of protein modification processGO:00314012990.025
response to radiationGO:00093141650.025
negative regulation of protein maturationGO:1903318790.025
organic hydroxy compound metabolic processGO:19016152030.025
adherens junction organizationGO:0034332280.024
regulation of ras protein signal transductionGO:00465781140.024
regulation of protein serine threonine kinase activityGO:00719001570.024
regulation of nucleotide catabolic processGO:00308111220.024
regulation of blood pressureGO:0008217930.024
cellular lipid metabolic processGO:00442553230.024
ribonucleotide metabolic processGO:00092592910.024
positive regulation of kinase activityGO:00336741550.024
digestive system developmentGO:00551232000.024
ossificationGO:00015032160.023
negative regulation of immune system processGO:00026832090.023
posttranscriptional regulation of gene expressionGO:00106081550.023
t cell proliferationGO:00420981200.023
cartilage developmentGO:00512161400.023
purine containing compound metabolic processGO:00725213110.023
telencephalon developmentGO:00215371860.022
regulation of anatomical structure sizeGO:00900661780.022
muscle cell differentiationGO:00426922610.022
Mouse
organophosphate catabolic processGO:00464342320.022
oxidation reduction processGO:00551143420.022
regulation of systemic arterial blood pressureGO:0003073610.022
male gamete generationGO:00482322850.022
regulation of actin cytoskeleton organizationGO:0032956840.022
hindbrain developmentGO:00309021280.022
response to extracellular stimulusGO:00099911270.022
neural precursor cell proliferationGO:00613511210.022
regulation of body fluid levelsGO:00508781620.022
negative regulation of intracellular signal transductionGO:19025321670.022
ribonucleoside catabolic processGO:00424542060.022
cellular nitrogen compound catabolic processGO:00442702800.021
germ cell developmentGO:00072811850.021
regulation of neuron deathGO:19012141340.021
respiratory tube developmentGO:00303231670.021
regulation of angiogenesisGO:0045765810.021
positive regulation of programmed cell deathGO:00430682180.021
developmental growth involved in morphogenesisGO:00605601380.021
positive regulation of cytokine productionGO:00018191740.021
sequestering of calcium ionGO:0051208180.021
negative regulation of angiogenesisGO:0016525250.021
negative regulation of vasculature developmentGO:1901343260.021
cell chemotaxisGO:0060326810.021
axonogenesisGO:00074092740.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.021
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.021
microtubule based processGO:00070172360.020
neuron projection guidanceGO:00974851410.020
regulation of intracellular protein transportGO:0033157820.020
organonitrogen compound catabolic processGO:19015652640.020
regulation of lymphocyte activationGO:00512492400.020
cell junction assemblyGO:0034329520.020
regulation of cell cycleGO:00517262810.019
cellular response to transforming growth factor beta stimulusGO:0071560880.019
neuron deathGO:00709971540.019
intrinsic apoptotic signaling pathwayGO:00971931320.019
metencephalon developmentGO:0022037890.019
regulation of kinase activityGO:00435492490.019
regulation of transferase activityGO:00513382630.019
regulation of purine nucleotide metabolic processGO:19005421690.019
cerebellum developmentGO:0021549770.019
organonitrogen compound biosynthetic processGO:19015661920.019
regulation of cell activationGO:00508652890.019
cellular amide metabolic processGO:0043603580.019
cerebellum morphogenesisGO:0021587420.019
negative regulation of reproductive processGO:2000242310.019
lipid biosynthetic processGO:00086101790.019
regulation of reproductive processGO:2000241660.019
regulation of cellular response to stressGO:00801351590.019
retina development in camera type eyeGO:00600411190.018
regulation of nucleocytoplasmic transportGO:0046822730.018
c21 steroid hormone biosynthetic processGO:000670030.018
regulation of cell growthGO:0001558910.018
leukocyte migrationGO:00509001240.018
positive regulation of hydrolase activityGO:00513451480.018
positive regulation of cell adhesionGO:0045785800.018
intracellular protein transportGO:00068862040.018
heterocycle catabolic processGO:00467002800.018
i kappab kinase nf kappab signalingGO:0007249850.018
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.018
cellular macromolecule catabolic processGO:00442652060.018
dna metabolic processGO:00062593030.018
epithelium migrationGO:0090132630.018
regulation of wnt signaling pathwayGO:00301111230.018
cytokine mediated signaling pathwayGO:00192211150.018
organic hydroxy compound biosynthetic processGO:1901617770.018
regulation of ion homeostasisGO:2000021640.017
neuroblast division in subventricular zoneGO:002184920.017
cellular alcohol metabolic processGO:004410730.017
stem cell proliferationGO:00720891170.017
nucleocytoplasmic transportGO:00069131390.017
negative regulation of phosphorylationGO:00423261660.017
positive regulation of protein phosphorylationGO:00019342420.017
vesicle organizationGO:0016050600.017
cellular response to cytokine stimulusGO:00713451890.016
carbohydrate derivative biosynthetic processGO:19011371830.016
proteolysis involved in cellular protein catabolic processGO:00516031470.016
regulation of organ morphogenesisGO:20000271440.016
striated muscle cell developmentGO:00550021250.016
embryonic organ morphogenesisGO:00485622760.016
regulation of t cell activationGO:00508631700.016
cell matrix adhesionGO:0007160680.016
regulation of response to woundingGO:19030341890.016
peptidyl tyrosine modificationGO:00182121450.016
defense response to gram negative bacteriumGO:0050829280.016
lymphocyte proliferationGO:00466511640.016
peptide metabolic processGO:0006518460.016
nuclear importGO:0051170950.016
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.016
cell type specific apoptotic processGO:00972852680.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.015
regulation of defense responseGO:00313472330.015
regulation of cytoplasmic transportGO:19036491120.015
cell growthGO:00160491300.015
positive regulation of lymphocyte activationGO:00512511400.015
response to light stimulusGO:00094161350.015
skeletal muscle organ developmentGO:00605381630.015
regulation of protein transportGO:00512231630.015
negative regulation of peptidase activityGO:0010466460.015
epithelial cell migrationGO:0010631630.015
mesenchyme developmentGO:00604851520.015
wound healingGO:00420601570.015
Rat
plasma membrane organizationGO:0007009900.015
nucleoside triphosphate metabolic processGO:00091412300.015
protein localization to membraneGO:00726571080.015
negative regulation of hydrolase activityGO:0051346710.015
positive regulation of nucleotide metabolic processGO:00459811140.015
single organism nuclear importGO:1902593950.015
oocyte constructionGO:000730820.015
nucleoside catabolic processGO:00091642060.015
positive regulation of cellular catabolic processGO:00313311480.015
response to acid chemicalGO:00011011110.015
regulation of tooth mineralizationGO:007017020.015
sensory system developmentGO:004888030.015
canonical wnt signaling pathwayGO:00600701300.014
Mouse
t cell activationGO:00421102890.014
epithelial cell proliferationGO:00506731740.014
regulation of system processGO:00440572000.014
muscle tissue developmentGO:00605373080.014
myosin filament assemblyGO:003103420.014
myosin filament organizationGO:003103330.014
regulation of homeostatic processGO:00328441820.014
production of molecular mediator of immune responseGO:00024401030.014
endocytosisGO:00068971680.014
response to organic cyclic compoundGO:00140701980.014
Rat
non canonical wnt signaling pathwayGO:0035567330.014
negative regulation of protein phosphorylationGO:00019331260.014
cellular protein complex assemblyGO:00436231160.014
muscle cell proliferationGO:0033002520.014
cellular response to dna damage stimulusGO:00069742070.014
organelle assemblyGO:00709251770.014
neutrophil migrationGO:1990266370.014
small molecule biosynthetic processGO:00442831320.014
regulation of protein localizationGO:00328802310.013
rhythmic processGO:00485111740.013
regulation of blood vessel sizeGO:0050880560.013
protein localization to organelleGO:00333651850.013
chondroitin sulfate proteoglycan metabolic processGO:0050654200.013
vasodilationGO:0042311280.013
regulation of leukocyte proliferationGO:00706631210.013
innate immune responseGO:00450871570.013
glial cell developmentGO:0021782540.013
vascular process in circulatory systemGO:0003018620.013
skeletal system morphogenesisGO:00487052030.013
activation of mapk activityGO:0000187590.013
ameboidal type cell migrationGO:00016671280.013
positive regulation of purine nucleotide metabolic processGO:19005441140.013
striated muscle myosin thick filament assemblyGO:007168810.013
regulation of protein kinase activityGO:00458592320.013
negative regulation of prostatic bud formationGO:006068640.013
negative regulation of alcohol biosynthetic processGO:190293140.013
negative regulation of phosphate metabolic processGO:00459361840.013
multicellular organismal metabolic processGO:0044236280.013
placenta developmentGO:00018901400.013
response to endoplasmic reticulum stressGO:0034976530.013
proteoglycan metabolic processGO:0006029380.013
odontogenesisGO:0042476780.013
sequestering of metal ionGO:0051238190.013
negative regulation of immune effector processGO:0002698550.013
b cell activationGO:00421131610.013
regulation of nucleotide metabolic processGO:00061401690.013
axon guidanceGO:00074111410.013
organic cyclic compound catabolic processGO:19013612950.013
positive regulation of apoptotic processGO:00430652170.013
cation transmembrane transportGO:00986552660.012
defense response to bacteriumGO:00427421190.012
reactive oxygen species biosynthetic processGO:190340980.012
engulfment of apoptotic cellGO:004365230.012
oocyte axis specificationGO:000730920.012
regulation of cell substrate adhesionGO:0010810730.012
positive regulation of map kinase activityGO:0043406840.012
nuclear transportGO:00511691390.012
gliogenesisGO:00420631410.012
regulation of peptidyl tyrosine phosphorylationGO:0050730930.012
cellular metal ion homeostasisGO:00068751510.012
response to inorganic substanceGO:0010035960.012
positive regulation of immune effector processGO:00026991070.012
cofactor metabolic processGO:0051186800.012
cellular alcohol biosynthetic processGO:004410830.012
regulation of biomineral tissue developmentGO:0070167330.012
regulation of membrane protein ectodomain proteolysisGO:005104330.012
regulation of extent of cell growthGO:0061387520.012
negative regulation of cellular component organizationGO:00511291940.012
nitrogen compound transportGO:00717052710.012
tissue remodelingGO:00487711020.012
regulation of steroid hormone biosynthetic processGO:009003040.012
regulation of membrane potentialGO:00423911920.012
regulation of t cell proliferationGO:0042129920.012
connective tissue developmentGO:00614481790.012
positive regulation of cell activationGO:00508671580.012
stem cell differentiationGO:00488632680.011
nucleoside phosphate biosynthetic processGO:1901293790.011
regulation of vesicle mediated transportGO:00606271390.011
reactive oxygen species metabolic processGO:0072593840.011
regulation of multi organism processGO:00439001110.011
respiratory system developmentGO:00605411900.011
cellular protein catabolic processGO:00442571550.011
response to organonitrogen compoundGO:00102432460.011
Rat
cellular ion homeostasisGO:00068731650.011
organophosphate biosynthetic processGO:00904071220.011
negative regulation of mitotic cell cycleGO:0045930580.011
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.011
response to peptide hormoneGO:00434341270.011
adaptive immune responseGO:00022501550.011
regulation of engulfment of apoptotic cellGO:190107420.011
regulation of sphingolipid mediated signaling pathwayGO:190206820.011
cellular modified amino acid metabolic processGO:0006575630.011
tissue homeostasisGO:00018941150.011
wnt signaling pathway calcium modulating pathwayGO:000722320.011
mineralocorticoid biosynthetic processGO:000670510.011
negative regulation of neuron deathGO:1901215980.011
lipid transportGO:0006869980.011
cellular response to organic cyclic compoundGO:0071407870.011
microglia differentiationGO:001400420.011
endocrine processGO:0050886390.011
rhodopsin mediated signaling pathwayGO:001605640.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
glycosyl compound catabolic processGO:19016582060.011
positive regulation of growthGO:00459271040.011
reactive nitrogen species metabolic processGO:200105700.011
primary neural tube formationGO:0014020950.011
transmission of nerve impulseGO:0019226760.011
lipid localizationGO:00108761260.011
regulation of translationGO:0006417710.011
regulation of reactive oxygen species biosynthetic processGO:190342620.011
coagulationGO:0050817780.011
response to oxidative stressGO:00069791230.011
epithelial tube morphogenesisGO:00605623030.011
translationGO:0006412930.011
acute inflammatory responseGO:0002526410.011
mitotic cytokinesisGO:000028140.011
neural tube developmentGO:00219151600.011
mesenchymal cell proliferationGO:0010463440.011
negative regulation of defense responseGO:0031348770.011
regulation of cell cycle processGO:00105641600.011
positive regulation of chemotaxisGO:0050921380.010
regulation of cell sizeGO:0008361720.010
nucleoside triphosphate catabolic processGO:00091432050.010
regulation of androgen receptor signaling pathwayGO:006076530.010
regulation of glial cell differentiationGO:0045685410.010
regulation of protein localization to nucleusGO:1900180600.010
leukocyte chemotaxisGO:0030595690.010
mucopolysaccharide metabolic processGO:1903510250.010
embryonic epithelial tube formationGO:00018381300.010
neuron projection extension involved in neuron projection guidanceGO:1902284140.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
regulation of tube sizeGO:0035150570.010
positive regulation of smooth muscle cell migrationGO:001491140.010
syncytium formation by plasma membrane fusionGO:0000768420.010
myeloid cell differentiationGO:00300992330.010
nucleotide catabolic processGO:00091662170.010
exocrine system developmentGO:0035272450.010
bone remodelingGO:0046849530.010
maintenance of cell numberGO:009872730.010
purine nucleotide catabolic processGO:00061952110.010
response to amino acidGO:0043200370.010
positive regulation of apoptotic signaling pathwayGO:2001235950.010
regulation of production of molecular mediator of immune responseGO:0002700650.010
purine ribonucleoside catabolic processGO:00461302050.010
sulfur compound biosynthetic processGO:0044272370.010
positive regulation of phospholipase c activityGO:001086320.010
cellular response to organonitrogen compoundGO:00714171450.010
hindbrain morphogenesisGO:0021575460.010
regulation of establishment of protein localizationGO:00702011810.010

Sdc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
nervous system diseaseDOID:86300.041
musculoskeletal system diseaseDOID:1700.039
connective tissue diseaseDOID:6500.036
bone development diseaseDOID:008000600.036
bone diseaseDOID:008000100.036
eye diseaseDOID:561400.027
eye and adnexa diseaseDOID:149200.027
sensory system diseaseDOID:005015500.027
osteochondrodysplasiaDOID:225600.022
inherited metabolic disorderDOID:65500.020
disease of metabolismDOID:001466700.020
immune system diseaseDOID:291400.020
retinal diseaseDOID:567900.017
central nervous system diseaseDOID:33100.016
lipid metabolism disorderDOID:314600.015
retinal degenerationDOID:846600.014
non syndromic intellectual disabilityDOID:005088900.010
disease of mental healthDOID:15000.010
developmental disorder of mental healthDOID:006003700.010
specific developmental disorderDOID:006003800.010
intellectual disabilityDOID:105900.010