Mus musculus

0 known processes

Adam4

a disintegrin and metallopeptidase domain 4

(Aliases: tMDCV,AV274654)

Adam4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of thymocyte migrationGO:200041220.441
negative regulation of protein activation cascadeGO:200025830.369
positive regulation of protein kinase b signalingGO:0051897320.229
negative regulation of complement activationGO:004591630.161
regulation of cellular amine metabolic processGO:0033238200.148
gliogenesisGO:00420631410.101
regulation of complement activation classical pathwayGO:003045010.100
regulation of eosinophil migrationGO:200041620.096
positive regulation of eosinophil migrationGO:200041820.079
multicellular organismal signalingGO:0035637910.079
positive regulation of cellular amino acid metabolic processGO:004576430.078
apoptotic signaling pathwayGO:00971903060.074
positive regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030910.071
entry into cell of other organism involved in symbiotic interactionGO:0051806150.069
regulation of secretion by cellGO:19035302490.068
protein kinase b signalingGO:0043491740.067
neuronal action potentialGO:0019228540.067
t helper 2 cell cytokine productionGO:003574540.066
cell maturationGO:00484691270.064
thymocyte migrationGO:007267920.063
transmembrane transportGO:00550854120.063
amine metabolic processGO:0009308450.059
regulation of cellular amino acid metabolic processGO:000652150.057
activation of mapk activity involved in innate immune responseGO:003541920.054
negative regulation of neuron apoptotic processGO:0043524920.054
neural precursor cell proliferationGO:00613511210.053
regulation of lymphocyte activationGO:00512492400.049
cellular ketone metabolic processGO:0042180840.046
pma inducible membrane protein ectodomain proteolysisGO:005108810.045
regulation of organelle organizationGO:00330432890.045
sequestering of calcium ionGO:0051208180.044
entry into hostGO:0044409150.043
eosinophil migrationGO:007267730.043
negative regulation of t cell cytokine productionGO:000272510.042
cell type specific apoptotic processGO:00972852680.041
germ cell developmentGO:00072811850.041
cytoplasmic transportGO:00164822340.041
regulation of thymocyte migrationGO:200041020.040
peptidyl amino acid modificationGO:00181933360.039
learningGO:0007612980.039
regulation of neuron apoptotic processGO:00435231220.039
leukocyte differentiationGO:00025213420.039
positive regulation of cellular catabolic processGO:00313311480.038
mesenchyme developmentGO:00604851520.037
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.036
stem cell differentiationGO:00488632680.036
substrate dependent cell migrationGO:0006929180.036
extracellular matrix dependent thymocyte migrationGO:007268010.035
prevention of polyspermyGO:006046840.034
myelinationGO:0042552740.034
regulation of apoptotic signaling pathwayGO:20012331970.034
synaptic transmissionGO:00072683290.034
negative regulation of protein complex disassemblyGO:0043242220.034
protein importGO:00170381010.033
asymmetric stem cell divisionGO:009872230.033
ensheathment of neuronsGO:0007272760.033
regulation of cytoskeleton organizationGO:00514931220.033
regulation of membrane potentialGO:00423911920.032
b cell differentiationGO:0030183780.032
protein localization to organelleGO:00333651850.031
protein polymerizationGO:0051258570.031
negative regulation of immune effector processGO:0002698550.031
second messenger mediated signalingGO:0019932730.030
calcium mediated signalingGO:0019722460.030
cellular amine metabolic processGO:0044106440.029
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.029
positive regulation of membrane protein ectodomain proteolysisGO:005104430.028
cellular response to dna damage stimulusGO:00069742070.028
transmission of nerve impulseGO:0019226760.028
cognitionGO:00508901490.027
activation of immune responseGO:00022531380.027
negative regulation of immune system processGO:00026832090.027
regulation of protein import into nucleusGO:0042306520.027
monocyte extravasationGO:003569620.026
mitochondrion organizationGO:00070051340.026
purine nucleotide metabolic processGO:00061633020.026
regulation of protein depolymerizationGO:1901879260.026
cellular amino acid metabolic processGO:00065201030.026
regulation of establishment of protein localizationGO:00702011810.026
anion transportGO:00068201770.025
carbohydrate derivative biosynthetic processGO:19011371830.025
axon ensheathmentGO:0008366760.025
tumor necrosis factor ligand superfamily member 11 productionGO:007253510.025
stem cell developmentGO:00488642190.024
response to inorganic substanceGO:0010035960.024
renal system developmentGO:00720012250.024
protein localization to membraneGO:00726571080.024
positive regulation of protein modification processGO:00314012990.024
regulation of cellular catabolic processGO:00313292420.023
regulation of ion transmembrane transporter activityGO:0032412540.023
regulation of monocyte extravasationGO:200043720.023
regulation of protein kinase b signalingGO:0051896560.023
intracellular protein transportGO:00068862040.023
asymmetric neuroblast divisionGO:005505910.022
cell divisionGO:00513011200.022
response to amino acidGO:0043200370.022
nucleotide metabolic processGO:00091173320.022
sequestering of metal ionGO:0051238190.022
protein import into nucleusGO:0006606950.022
striated muscle tissue developmentGO:00147062930.022
small gtpase mediated signal transductionGO:0007264970.021
regulation of multi organism processGO:00439001110.021
regulation of fibronectin dependent thymocyte migrationGO:200041310.021
reactive oxygen species metabolic processGO:0072593840.021
response to radiationGO:00093141650.021
neuron apoptotic processGO:00514021420.021
lymphocyte differentiationGO:00300982420.021
bronchiole morphogenesisGO:006043610.021
positive regulation of cell cycleGO:0045787920.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.020
regulation of interleukin 5 secretionGO:200066220.020
regulation of cellular response to stressGO:00801351590.020
regulation of cellular ketone metabolic processGO:0010565660.020
regulation of membrane protein ectodomain proteolysisGO:005104330.020
positive regulation of cardiac muscle cell apoptotic processGO:001066630.020
nucleocytoplasmic transportGO:00069131390.020
membrane organizationGO:00610242450.020
glial cell differentiationGO:00100011310.020
cytokine productionGO:00018163190.020
mesenchymal epithelial cell signaling involved in lung developmentGO:006049610.019
regulation of t cell activationGO:00508631700.019
positive regulation of protein phosphorylationGO:00019342420.019
action potentialGO:0001508780.019
regulation of microtubule polymerization or depolymerizationGO:0031110200.019
sensory perceptionGO:00076002450.019
protein targetingGO:00066051430.019
regulation of response to woundingGO:19030341890.019
cellular component assembly involved in morphogenesisGO:00109271390.019
myelination in peripheral nervous systemGO:0022011190.019
cation transportGO:00068123990.019
hematopoietic progenitor cell differentiationGO:00022441430.019
mitotic cell cycle processGO:19030471590.019
organic acid transportGO:00158491010.018
myeloid leukocyte migrationGO:0097529570.018
protein maturationGO:00516041760.018
cell cell recognitionGO:0009988440.018
positive regulation of cellular amine metabolic processGO:003324050.018
learning or memoryGO:00076111480.018
rho protein signal transductionGO:0007266320.017
negative regulation of multi organism processGO:0043901680.017
bone remodelingGO:0046849530.017
neuron deathGO:00709971540.017
negative regulation of cytoskeleton organizationGO:0051494360.017
epidermis developmentGO:00085441870.017
response to reactive oxygen speciesGO:0000302560.017
regulation of protein complex disassemblyGO:0043244280.017
b cell activationGO:00421131610.017
negative regulation of macrophage apoptotic processGO:200011030.017
regulation of t helper 2 cell cytokine productionGO:200055130.016
regulation of organ morphogenesisGO:20000271440.016
regulation of immunological synapse formationGO:200052020.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
nuclear transportGO:00511691390.016
microtubule based processGO:00070172360.016
ras protein signal transductionGO:0007265770.016
divalent inorganic cation transportGO:00725111780.016
regulation of relaxation of muscleGO:190107780.016
negative regulation of neuron deathGO:1901215980.016
embryonic genitalia morphogenesisGO:003053840.016
blood vessel morphogenesisGO:00485142850.016
regulation of timing of cell differentiationGO:0048505110.016
transforming growth factor beta receptor signaling pathwayGO:0007179710.016
negative regulation of homeostatic processGO:0032845710.015
innate immune responseGO:00450871570.015
regulation of actin nucleationGO:005112540.015
myeloid cell homeostasisGO:00022621140.015
purine nucleotide biosynthetic processGO:0006164650.015
positive regulation of nucleotide metabolic processGO:00459811140.015
regulation of neuron deathGO:19012141340.015
regulation of protein localizationGO:00328802310.015
negative regulation of protein depolymerizationGO:1901880210.015
entry into host cellGO:0030260150.015
visual learningGO:0008542440.015
ribose phosphate metabolic processGO:00196932910.015
purine nucleotide catabolic processGO:00061952110.015
divalent inorganic cation homeostasisGO:00725071380.015
glial cell developmentGO:0021782540.015
microtubule cytoskeleton organizationGO:00002261570.015
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.015
schwann cell developmentGO:0014044220.015
organonitrogen compound biosynthetic processGO:19015661920.015
developmental maturationGO:00217001930.015
regulation of epithelial cell proliferationGO:00506781410.015
cellular metal ion homeostasisGO:00068751510.014
positive regulation of atpase activityGO:003278130.014
cellularizationGO:000734910.014
locomotory behaviorGO:00076261950.014
nucleoside phosphate metabolic processGO:00067533380.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.014
protein depolymerizationGO:0051261340.014
regulation of leukocyte differentiationGO:19021051590.014
g protein coupled receptor signaling pathwayGO:00071862430.014
organic cyclic compound catabolic processGO:19013612950.014
spermatid developmentGO:00072861080.014
rhythmic processGO:00485111740.014
regulation of leukocyte mediated immunityGO:00027031040.014
establishment of neuroblast polarityGO:004520010.014
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.014
regulation of cell migrationGO:00303342190.013
positive regulation of hydrolase activityGO:00513451480.013
regulation of secretionGO:00510462740.013
cellular homeostasisGO:00197252400.013
oligodendrocyte differentiationGO:0048709530.013
response to light stimulusGO:00094161350.013
organophosphate catabolic processGO:00464342320.013
cellular chemical homeostasisGO:00550822150.013
aromatic compound catabolic processGO:00194392860.013
nucleoside metabolic processGO:00091162460.013
skeletal muscle fiber developmentGO:0048741580.013
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.013
purine ribonucleotide metabolic processGO:00091502900.013
positive regulation of nervous system developmentGO:00519622210.013
camera type eye developmentGO:00430102660.013
negative regulation of organelle organizationGO:0010639900.013
positive regulation of cell deathGO:00109422240.013
response to organonitrogen compoundGO:00102432460.013
cd4 positive alpha beta t cell cytokine productionGO:003574340.012
regulation of nucleotide catabolic processGO:00308111220.012
olfactory learningGO:000835520.012
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.012
regulation of cellular component sizeGO:00325351210.012
maintenance of locationGO:0051235890.012
purine containing compound metabolic processGO:00725213110.012
regulation of protein transportGO:00512231630.012
cation homeostasisGO:00550802120.012
purine nucleoside triphosphate metabolic processGO:00091442260.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
regulation of inflammatory responseGO:00507271470.012
negative regulation of cellular amine metabolic processGO:003323910.012
nucleoside phosphate catabolic processGO:19012922220.012
production of molecular mediator of immune responseGO:00024401030.012
muscle tissue developmentGO:00605373080.012
plasma membrane organizationGO:0007009900.012
regulation of intracellular protein transportGO:0033157820.012
entry into other organism involved in symbiotic interactionGO:0051828150.012
natural killer cell activationGO:0030101440.012
response to transforming growth factor betaGO:0071559880.011
regulation of interleukin 13 secretionGO:200066520.011
organonitrogen compound catabolic processGO:19015652640.011
adult locomotory behaviorGO:0008344910.011
regulation of cell cycleGO:00517262810.011
actin mediated cell contractionGO:0070252150.011
antimicrobial peptide biosynthetic processGO:000277720.011
negative regulation of growthGO:0045926990.011
negative regulation of interleukin 5 productionGO:003271440.011
viral processGO:0016032410.011
cellular protein complex disassemblyGO:0043624360.011
heterocycle catabolic processGO:00467002800.011
muscle cell differentiationGO:00426922610.011
negative regulation of protein processingGO:0010955790.011
cellular response to cytokine stimulusGO:00713451890.011
organic anion transportGO:00157111370.011
axonogenesisGO:00074092740.011
positive regulation of kinase activityGO:00336741550.011
cellular calcium ion homeostasisGO:00068741190.011
negative regulation of interleukin 13 secretionGO:200066610.011
sensory perception of chemical stimulusGO:0007606510.011
rac protein signal transductionGO:0016601130.011
spermatid differentiationGO:00485151150.011
purine nucleoside metabolic processGO:00422782410.011
placenta developmentGO:00018901400.011
positive regulation of transferase activityGO:00513471670.011
methionine transportGO:001582110.011
actin filament polymerizationGO:0030041440.011
negative regulation of cell proliferationGO:00082852960.011
detection of chemical stimulus involved in sensory perception of smellGO:005091140.011
regulation of ion transmembrane transportGO:00347651190.011
schwann cell differentiationGO:0014037260.011
morphogenesis of a branching structureGO:00017632030.011
regulation of notch signaling pathwayGO:0008593350.011
negative regulation of cell sizeGO:004579230.011
regulation of nucleotide metabolic processGO:00061401690.011
regulation of t cell costimulationGO:200052320.011
epithelial tube morphogenesisGO:00605623030.011
cellular macromolecule catabolic processGO:00442652060.011
fertilizationGO:00095661270.011
ribonucleotide metabolic processGO:00092592910.011
macromolecule catabolic processGO:00090572810.011
regulation of defense responseGO:00313472330.011
glycoprotein biosynthetic processGO:0009101890.011
establishment of protein localization to organelleGO:00725941180.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.010
negative regulation of interleukin 13 productionGO:003269620.010
positive regulation of antimicrobial humoral responseGO:000276020.010
lymphocyte proliferationGO:00466511640.010
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.010
striated muscle cell developmentGO:00550021250.010
protein catabolic processGO:00301632210.010
single organism nuclear importGO:1902593950.010
glycoprotein metabolic processGO:00091001160.010
mechanoreceptor differentiationGO:0042490670.010
peptidyl tyrosine phosphorylationGO:00181081430.010
regulation of protein maturationGO:1903317960.010
sensory organ boundary specificationGO:000805210.010
positive regulation of cell cycle processGO:0090068610.010
regulation of transporter activityGO:0032409570.010
glycosyl compound metabolic processGO:19016572460.010
lymphocyte activation involved in immune responseGO:0002285930.010
respiratory system developmentGO:00605411900.010

Adam4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.023
disease of anatomical entityDOID:700.023
central nervous system diseaseDOID:33100.023
electroclinical syndromeDOID:005070100.023
brain diseaseDOID:93600.023
epilepsy syndromeDOID:182600.023
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
musculoskeletal system diseaseDOID:1700.014
sensory system diseaseDOID:005015500.011
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
immune system cancerDOID:006008300.010
hematologic cancerDOID:253100.010