Mus musculus

21 known processes

Adam2

a disintegrin and metallopeptidase domain 2

(Aliases: Ph30-beta,Ftnb,AI323749)

Adam2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
fertilizationGO:00095661270.381
Mouse
action potentialGO:0001508780.378
Mouse
regulation of defense responseGO:00313472330.377
Mouse
cytokine productionGO:00018163190.318
Mouse
cell adhesionGO:00071553290.307
male gamete generationGO:00482322850.291
Rat
binding of sperm to zona pellucidaGO:0007339340.275
Mouse
single fertilizationGO:0007338820.270
Mouse
spermatogenesisGO:00072832840.257
Rat
germ cell developmentGO:00072811850.188
sperm egg recognitionGO:0035036370.171
Mouse
response to radiationGO:00093141650.160
regulation of response to woundingGO:19030341890.153
Mouse
spermatid differentiationGO:00485151150.144
cell cell recognitionGO:0009988440.144
Mouse
spermatid developmentGO:00072861080.136
inflammatory responseGO:00069542440.133
Mouse
protein catabolic processGO:00301632210.132
Mouse
transmission of nerve impulseGO:0019226760.129
Mouse
regulation of membrane potentialGO:00423911920.123
Mouse
myeloid cell homeostasisGO:00022621140.113
Mouse
wound healingGO:00420601570.097
positive regulation of apoptotic processGO:00430652170.089
Mouse
chemotaxisGO:00069352470.086
Mouse
positive regulation of cell deathGO:00109422240.085
Mouse
regulation of protein catabolic processGO:00421761080.084
Mouse
exocytosisGO:00068871210.082
multicellular organismal signalingGO:0035637910.081
Mouse
proteolysis involved in cellular protein catabolic processGO:00516031470.081
regulation of proteolysisGO:00301621640.079
Mouse
cell recognitionGO:0008037830.078
Mouse
multi multicellular organism processGO:00447061090.077
coagulationGO:0050817780.077
regulation of homeostatic processGO:00328441820.076
Mouse
cellular response to lipidGO:00713961450.073
regulation of cell activationGO:00508652890.072
Mouse
cellular ketone metabolic processGO:0042180840.072
sensory perception of mechanical stimulusGO:00509541070.071
regulation of lipid metabolic processGO:00192161180.068
regulation of innate immune responseGO:0045088910.068
Mouse
macromolecule catabolic processGO:00090572810.067
Mouse
positive regulation of cell migrationGO:00303351090.061
Mouse
lymphocyte differentiationGO:00300982420.060
Mouse
membrane organizationGO:00610242450.057
negative regulation of immune system processGO:00026832090.057
negative regulation of molecular functionGO:00440922580.057
microtubule based processGO:00070172360.055
protein maturationGO:00516041760.053
androgen biosynthetic processGO:000670240.053
positive regulation of innate immune responseGO:0045089800.052
Mouse
neuronal action potentialGO:0019228540.052
Mouse
immune response regulating signaling pathwayGO:00027641250.052
Mouse
protein processingGO:00164851630.050
blood coagulationGO:0007596760.050
hindbrain developmentGO:00309021280.048
cellular macromolecule catabolic processGO:00442652060.047
eosinophil migrationGO:007267730.046
Mouse
negative regulation of phosphorus metabolic processGO:00105631840.046
positive regulation of defense responseGO:00313491240.046
Mouse
heart morphogenesisGO:00030071780.045
Mouse
leukocyte differentiationGO:00025213420.045
Mouse
peptidyl serine modificationGO:0018209830.045
negative regulation of protein metabolic processGO:00512482820.044
regulation of cellular ketone metabolic processGO:0010565660.044
small molecule biosynthetic processGO:00442831320.044
regulation of wound healingGO:0061041400.043
alcohol metabolic processGO:00060661160.043
cell chemotaxisGO:0060326810.043
Mouse
dna metabolic processGO:00062593030.043
paraxial mesodermal cell differentiationGO:004834220.042
hemostasisGO:0007599780.042
carbohydrate metabolic processGO:00059752300.042
regulation of vesicle mediated transportGO:00606271390.040
single organism cell adhesionGO:00986021560.040
Mouse
sperm motilityGO:0030317470.040
regulation of protein processingGO:0070613960.039
extracellular matrix dependent thymocyte migrationGO:007268010.039
Mouse
regulation of lymphocyte activationGO:00512492400.038
Mouse
cellular amino acid metabolic processGO:00065201030.038
positive regulation of programmed cell deathGO:00430682180.038
Mouse
regulation of testosterone biosynthetic processGO:200022420.037
cellular response to molecule of bacterial originGO:0071219830.037
positive regulation of cell adhesionGO:0045785800.036
Mouse
anion transmembrane transportGO:0098656710.036
negative regulation of neuron apoptotic processGO:0043524920.036
Mouse
modification dependent macromolecule catabolic processGO:00436321330.036
regulation of blood coagulationGO:0030193280.036
positive regulation of cytokine productionGO:00018191740.036
Mouse
testosterone biosynthetic processGO:006137020.036
ensheathment of neuronsGO:0007272760.035
Mouse
ossificationGO:00015032160.035
cellular metal ion homeostasisGO:00068751510.035
sensory perceptionGO:00076002450.034
axonogenesisGO:00074092740.034
myeloid cell differentiationGO:00300992330.034
cellular protein catabolic processGO:00442571550.034
transmembrane transportGO:00550854120.034
regulation of tissue remodelingGO:0034103380.034
Mouse
cell type specific apoptotic processGO:00972852680.034
Mouse
fourth ventricle developmentGO:002159220.033
somatotropin secreting cell differentiationGO:006012640.033
lipid biosynthetic processGO:00086101790.032
regulation of protein serine threonine kinase activityGO:00719001570.032
Mouse
modification dependent protein catabolic processGO:00199411330.032
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.031
Mouse
cytokine secretionGO:0050663720.031
positive regulation of cell motilityGO:20001471160.031
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.031
positive regulation of acute inflammatory responseGO:0002675160.031
Mouse
regulation of mapk cascadeGO:00434082480.030
Mouse
calcium ion dependent exocytosisGO:0017156350.030
microtubule cytoskeleton organizationGO:00002261570.029
pma inducible membrane protein ectodomain proteolysisGO:005108810.029
Mouse
intracellular protein transportGO:00068862040.029
cytokine biosynthetic processGO:0042089680.029
cellular chemical homeostasisGO:00550822150.029
sequestering of metal ionGO:0051238190.029
negative regulation of cellular protein metabolic processGO:00322692470.029
negative regulation of phosphate metabolic processGO:00459361840.028
regulation of secretionGO:00510462740.028
regulation of coagulationGO:0050818310.028
response to drugGO:0042493750.028
Mouse
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.028
regulation of organelle organizationGO:00330432890.028
regulation of transferase activityGO:00513382630.028
Mouse
proteasomal protein catabolic processGO:0010498980.028
cation transportGO:00068123990.028
nuclear divisionGO:00002801580.028
negative regulation of cell activationGO:00508661110.028
regulation of protein complex assemblyGO:0043254830.027
positive regulation of leukocyte differentiationGO:1902107860.027
Mouse
developmental maturationGO:00217001930.027
reactive oxygen species metabolic processGO:0072593840.027
regulation of cellular protein catabolic processGO:1903362610.026
regulation of cell motilityGO:20001452360.026
Mouse
positive regulation of protein phosphorylationGO:00019342420.026
Mouse
embryonic placenta developmentGO:0001892980.026
positive regulation of lymphocyte activationGO:00512511400.026
Mouse
regulation of actin filament based processGO:0032970990.026
positive regulation of cytosolic calcium ion concentrationGO:0007204650.026
bone resorptionGO:0045453380.025
Mouse
actin cytoskeleton organizationGO:00300362200.025
regulation of mitotic cell cycleGO:00073461260.025
locomotory behaviorGO:00076261950.025
Mouse
regulation of metal ion transportGO:00109591060.025
positive regulation of membrane protein ectodomain proteolysisGO:005104430.025
Mouse
organophosphate biosynthetic processGO:00904071220.025
regulation of ketone biosynthetic processGO:001056620.025
leukocyte proliferationGO:00706611720.025
cellular calcium ion homeostasisGO:00068741190.025
negative regulation of lymphocyte activationGO:0051250910.024
ubiquitin dependent protein catabolic processGO:00065111290.024
mapk cascadeGO:00001652810.024
Mouse
g protein coupled receptor signaling pathwayGO:00071862430.024
leukocyte homeostasisGO:0001776790.024
Mouse
regulation of cellular component sizeGO:00325351210.024
b cell activationGO:00421131610.024
Mouse
cellular response to hormone stimulusGO:00328701500.024
fibronectin dependent thymocyte migrationGO:007268110.023
Mouse
regulation of cell adhesionGO:00301551540.023
Mouse
regulation of transforming growth factor beta2 productionGO:003290920.023
pallium developmentGO:00215431200.023
regulation of myeloid cell differentiationGO:0045637960.023
innate immune responseGO:00450871570.023
Mouse
sensory system developmentGO:004888030.023
regionalizationGO:00030023370.022
regulation of apoptotic signaling pathwayGO:20012331970.022
sulfur compound metabolic processGO:00067901000.022
regulation of cellular component biogenesisGO:00440871810.022
muscle tissue developmentGO:00605373080.022
neuromuscular processGO:0050905990.022
b cell mediated immunityGO:0019724710.022
positive regulation of protein transportGO:0051222930.022
neuron apoptotic processGO:00514021420.022
Mouse
mitotic cell cycleGO:00002781950.022
ion transmembrane transportGO:00342203610.022
regulation of protein localizationGO:00328802310.022
single organismal cell cell adhesionGO:00163371310.022
Mouse
lateral line system developmentGO:004892510.022
negative regulation of kinase activityGO:0033673810.022
homeostasis of number of cellsGO:00488722100.021
Mouse
actin filament organizationGO:00070151130.021
myelination in peripheral nervous systemGO:0022011190.021
Mouse
regulation of cellular amino acid metabolic processGO:000652150.021
inorganic ion transmembrane transportGO:00986602340.021
interferon gamma productionGO:0032609670.021
cellular response to biotic stimulusGO:0071216920.021
cytosolic calcium ion homeostasisGO:0051480700.021
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.021
regulation of asymmetric cell divisionGO:000978640.021
regulation of establishment of protein localizationGO:00702011810.021
carbohydrate transportGO:0008643620.021
negative regulation of intracellular signal transductionGO:19025321670.021
oxidation reduction processGO:00551143420.021
regulation of secretion by cellGO:19035302490.020
glial cell developmentGO:0021782540.020
Mouse
cytokine metabolic processGO:0042107710.020
positive regulation of thymocyte migrationGO:200041220.020
Mouse
male meiosisGO:0007140370.020
regulation of hemostasisGO:1900046280.020
regulation of proteasomal protein catabolic processGO:0061136460.020
positive regulation of secretionGO:00510471300.020
oocyte constructionGO:000730820.020
regulation of leukocyte differentiationGO:19021051590.020
Mouse
cellular divalent inorganic cation homeostasisGO:00725031270.020
regulation of protein maturationGO:1903317960.020
protein modification by small protein conjugationGO:00324461870.020
telencephalon developmentGO:00215371860.019
vitamin a metabolic processGO:000677620.019
regulation of peptide hormone secretionGO:0090276750.019
regulation of fat cell differentiationGO:0045598810.019
glycerolipid metabolic processGO:00464861220.019
positive regulation of secondary heart field cardioblast proliferationGO:007251340.019
skeletal system morphogenesisGO:00487052030.019
isoprenoid metabolic processGO:0006720290.019
paraxial mesodermal cell fate commitmentGO:004834320.019
cytoplasmic transportGO:00164822340.019
maintenance of locationGO:0051235890.019
fat cell differentiationGO:00454441600.019
response to acid chemicalGO:00011011110.019
glycerophospholipid metabolic processGO:0006650710.019
amine metabolic processGO:0009308450.019
small gtpase mediated signal transductionGO:0007264970.019
sensory perception of soundGO:0007605970.019
response to vitamin dGO:003328030.019
metanephric loop of henle developmentGO:007223640.018
divalent inorganic cation homeostasisGO:00725071380.018
regulation of intracellular transportGO:00323861590.018
paramesonephric duct developmentGO:006120530.018
gliogenesisGO:00420631410.018
Mouse
cell maturationGO:00484691270.018
limbic system developmentGO:0021761720.018
mitotic cell cycle processGO:19030471590.018
negative regulation of transferase activityGO:0051348850.018
regulation of cytoskeleton organizationGO:00514931220.018
regulation of protein transportGO:00512231630.018
regulation of tumor necrosis factor ligand superfamily member 11 productionGO:200030710.018
Mouse
tissue remodelingGO:00487711020.017
Mouse
negative regulation of homeostatic processGO:0032845710.017
glucose transportGO:0015758560.017
cellular lipid metabolic processGO:00442553230.017
nitrogen compound transportGO:00717052710.017
release of sequestered calcium ion into cytosolGO:0051209420.017
response to organonitrogen compoundGO:00102432460.017
protein secretionGO:00093061110.017
negative regulation of protein processingGO:0010955790.017
leukocyte mediated immunityGO:00024431740.017
organelle fissionGO:00482851700.017
oocyte axis specificationGO:000730920.017
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.016
visual learningGO:0008542440.016
peptidyl serine phosphorylationGO:0018105740.016
positive regulation of proteolysisGO:0045862850.016
Mouse
rna processingGO:00063961050.016
activation of immune responseGO:00022531380.016
Mouse
negative regulation of cell cycleGO:00457861230.016
gland developmentGO:00487323300.016
positive regulation of eosinophil migrationGO:200041820.016
Mouse
t cell differentiation in thymusGO:0033077770.016
Mouse
protein ubiquitinationGO:00165671710.016
myelinationGO:0042552740.016
Mouse
regulation of exocytosisGO:0017157610.016
epithelial cell developmentGO:00020641590.016
establishment of organ orientationGO:004856110.016
nucleocytoplasmic transportGO:00069131390.016
cation transmembrane transportGO:00986552660.015
adult behaviorGO:00305341350.015
embryonic axis specificationGO:0000578300.015
positive regulation of fibronectin dependent thymocyte migrationGO:200041510.015
Mouse
renal system developmentGO:00720012250.015
anion transportGO:00068201770.015
positive regulation of response to woundingGO:1903036660.015
Mouse
negative regulation of protein maturationGO:1903318790.015
negative regulation of cellular component organizationGO:00511291940.015
regulation of cytoplasmic transportGO:19036491120.015
adaptive immune responseGO:00022501550.015
Mouse
steroid metabolic processGO:00082021190.015
organelle assemblyGO:00709251770.015
negative regulation of apoptotic signaling pathwayGO:20012341040.015
peptide hormone secretionGO:00300721090.015
cellular response to carbohydrate stimulusGO:0071322500.015
regulation of cellular response to stressGO:00801351590.015
activation of adenylate cyclase activityGO:000719040.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
protein modification by small protein conjugation or removalGO:00706472070.015
regulation of neuron projection developmentGO:00109751690.015
regulation of epithelial cell proliferationGO:00506781410.015
phagocytosisGO:0006909660.015
regulation of acute inflammatory responseGO:0002673270.015
Mouse
amino acid transmembrane transportGO:0003333370.015
regulation of cell migrationGO:00303342190.015
Mouse
response to purine containing compoundGO:0014074280.015
cellular response to parathyroid hormone stimulusGO:007137420.015
immunoglobulin mediated immune responseGO:0016064690.015
cellular modified amino acid metabolic processGO:0006575630.015
regulation of leukocyte mediated immunityGO:00027031040.015
skin developmentGO:00435882200.015
divalent metal ion transportGO:00708381720.014
regulation of cytokine productionGO:00018172660.014
Mouse
regulation of anatomical structure sizeGO:00900661780.014
striated muscle contractionGO:0006941450.014
regulation of actin cytoskeleton organizationGO:0032956840.014
learningGO:0007612980.014
placenta developmentGO:00018901400.014
negative regulation of protein phosphorylationGO:00019331260.014
regulation of cell cycle phase transitionGO:1901987770.014
terpenoid metabolic processGO:0006721250.014
nuclear transportGO:00511691390.014
intracellular receptor signaling pathwayGO:0030522740.014
phospholipid biosynthetic processGO:0008654360.014
single organism nuclear importGO:1902593950.014
positive regulation of protein modification processGO:00314012990.014
Mouse
negative regulation of proteolysisGO:0045861740.014
extracellular structure organizationGO:00430621480.014
postsynaptic membrane organizationGO:0001941180.014
positive regulation of inositol phosphate biosynthetic processGO:006073220.014
t cell differentiationGO:00302171740.013
Mouse
adult locomotory behaviorGO:0008344910.013
Mouse
metencephalon developmentGO:0022037890.013
bone mineralizationGO:0030282540.013
midgut developmentGO:000749440.013
extracellular matrix organizationGO:00301981470.013
calcium ion transportGO:00068161590.013
dephosphorylationGO:00163111290.013
protein targetingGO:00066051430.013
nucleoside phosphate biosynthetic processGO:1901293790.013
hypophysis morphogenesisGO:004885030.013
visual behaviorGO:0007632450.013
cellular response to growth factor stimulusGO:00713631970.013
Mouse
neuron projection guidanceGO:00974851410.013
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.013
establishment of endothelial blood brain barrierGO:001404530.013
axon ensheathmentGO:0008366760.013
Mouse
endocytosisGO:00068971680.013
t cell activationGO:00421102890.013
Mouse
cardiac right atrium morphogenesisGO:000321330.013
lymphocyte proliferationGO:00466511640.013
regulation of thymocyte apoptotic processGO:0070243140.012
Mouse
gastrulationGO:00073691160.012
specification of organ positionGO:001015930.012
phospholipid metabolic processGO:0006644870.012
myeloid leukocyte migrationGO:0097529570.012
Mouse
cellular response to lipopolysaccharideGO:0071222770.012
central nervous system morphogenesisGO:002155120.012
regulation of kinase activityGO:00435492490.012
Mouse
negative regulation of nervous system developmentGO:00519611560.012
positive regulation of cell activationGO:00508671580.012
Mouse
regulation of thymocyte migrationGO:200041020.012
Mouse
telencephalon cell migrationGO:0022029550.012
regulation of mitotic cell cycle phase transitionGO:1901990730.012
cardiac muscle tissue developmentGO:00487381300.012
regulation of reactive oxygen species metabolic processGO:2000377400.012
mrna processingGO:0006397630.012
regulation of membrane protein ectodomain proteolysisGO:005104330.012
Mouse
establishment of anatomical structure orientationGO:004856010.012
male sex differentiationGO:00466611090.012
organonitrogen compound biosynthetic processGO:19015661920.012
multicellular organism growthGO:00352641610.012
axon guidanceGO:00074111410.012
gonad developmentGO:00084061410.012
epithelial tube morphogenesisGO:00605623030.012
oogenesisGO:0048477560.012
regulation of lamellipodium assemblyGO:001059130.011
engulfment of apoptotic cellGO:004365230.011
positive regulation of t cell activationGO:00508701010.011
Mouse
cellular response to organonitrogen compoundGO:00714171450.011
oocyte developmentGO:0048599330.011
positive regulation of cytoskeleton organizationGO:0051495490.011
regulation of axon diameterGO:003113360.011
immune effector processGO:00022523210.011
biomineral tissue developmentGO:0031214640.011
detection of stimulusGO:0051606840.011
positive regulation of growthGO:00459271040.011
negative regulation of response to woundingGO:1903035770.011
steroid biosynthetic processGO:0006694470.011
negative regulation of cell migrationGO:0030336590.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
protein localization to organelleGO:00333651850.011
cellular response to organic cyclic compoundGO:0071407870.011
monosaccharide transportGO:0015749580.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.011
positive regulation of protein secretionGO:0050714520.011
innate immune response activating signal transductionGO:0002758500.011
Mouse
regulation of reproductive processGO:2000241660.011
Mouse
regulation of hydrolase activityGO:00513362460.011
retinoid metabolic processGO:0001523240.011
metal ion homeostasisGO:00550651890.011
negative regulation of protein modification processGO:00314001630.011
positive regulation of leukocyte apoptotic processGO:2000108210.011
Mouse
regulation of inositol phosphate biosynthetic processGO:001091930.011
ribose phosphate metabolic processGO:00196932910.011
neuron deathGO:00709971540.011
Mouse
embryonic skeletal system morphogenesisGO:0048704910.011
regulation of cell cycleGO:00517262810.011
kidney rudiment formationGO:007200330.011
regulation of lipid biosynthetic processGO:0046890540.011
axis elongation involved in somitogenesisGO:009024540.011
molting cycleGO:0042303900.010
regulation of lymphocyte mediated immunityGO:0002706840.010
regulation of body fluid levelsGO:00508781620.010
digestive system developmentGO:00551232000.010
bone remodelingGO:0046849530.010
Mouse
regulation of multi organism processGO:00439001110.010
Mouse
response to oxidative stressGO:00069791230.010
mesoderm morphogenesisGO:0048332640.010
acrosome reactionGO:0007340190.010
central nervous system neuron differentiationGO:00219531620.010
positive regulation of organelle organizationGO:00106381280.010
meiotic nuclear divisionGO:00071261150.010
negative regulation of mesenchymal cell proliferationGO:007220130.010
positive regulation of interleukin 8 productionGO:003275720.010
pharynx developmentGO:006046510.010
camera type eye developmentGO:00430102660.010
monocarboxylic acid metabolic processGO:00327871910.010
neuromuscular process controlling balanceGO:0050885590.010
negative regulation of defense responseGO:0031348770.010
defense response to bacteriumGO:00427421190.010
aminoglycan metabolic processGO:0006022340.010
limb developmentGO:00601731660.010
metanephric ascending thin limb developmentGO:007221820.010
regulation of ossificationGO:00302781120.010
cellular protein complex assemblyGO:00436231160.010
metanephric dct cell differentiationGO:007224030.010
ras protein signal transductionGO:0007265770.010
cellular response to peptideGO:1901653920.010

Adam2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.011
nervous system diseaseDOID:86300.011
disease of metabolismDOID:001466700.011