Mus musculus

90 known processes

Serpina1b

serine (or cysteine) preptidase inhibitor, clade A, member 1B

(Aliases: Spi1-2,D12Ucla2,PI2,Dom2,MGC117839)

Serpina1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of insulin receptor signaling pathwayGO:004662840.586
Mouse
regulation of protein kinase c activityGO:190001910.585
Mouse
ovarian follicle ruptureGO:000154320.537
Mouse
positive regulation of protein kinase c activityGO:190002010.531
Mouse
regulation of cholesterol metabolic processGO:0090181140.479
Mouse
regulation of renal output by angiotensinGO:000201920.372
Mouse
neutral lipid metabolic processGO:0006638570.354
Mouse
negative regulation of serine type endopeptidase activityGO:190000420.348
Rat
activation of nf kappab inducing kinase activityGO:000725040.346
Mouse
acylglycerol metabolic processGO:0006639550.341
Mouse
triglyceride metabolic processGO:0006641510.333
Mouse
macromolecule glycosylationGO:0043413550.316
response to chromateGO:004668710.312
Rat
sterol metabolic processGO:0016125580.300
Mouse
renin angiotensin regulation of aldosterone productionGO:000201830.298
Mouse
astrocyte activationGO:004814320.276
Mouse
amine metabolic processGO:0009308450.270
protein glycosylationGO:0006486550.256
cellular amino acid metabolic processGO:00065201030.219
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressureGO:000199830.217
Mouse
alcohol metabolic processGO:00060661160.216
Mouse
regulation of fatty acid biosynthetic processGO:0042304120.208
Mouse
glycerolipid metabolic processGO:00464861220.207
Mouse
glycosylationGO:0070085620.199
hexose metabolic processGO:0019318980.199
Mouse
carboxylic acid biosynthetic processGO:0046394860.193
Mouse
regulation of insulin receptor signaling pathwayGO:0046626210.189
Mouse
carbohydrate metabolic processGO:00059752300.187
negative regulation of lipid metabolic processGO:0045833300.184
Mouse
cellular lipid metabolic processGO:00442553230.178
Mouse
cellular amine metabolic processGO:0044106440.177
regulation of cellular amine metabolic processGO:0033238200.174
protein n linked glycosylationGO:0006487120.169
regulation of cellular amino acid metabolic processGO:000652150.168
cholesterol metabolic processGO:0008203560.164
Mouse
regulation of hydrolase activityGO:00513362460.163
positive regulation of fatty acid biosynthetic processGO:004572330.159
Mouse
fatty acid metabolic processGO:00066311210.145
Mouse
lipid biosynthetic processGO:00086101790.141
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.138
negative regulation of protein metabolic processGO:00512482820.137
regulation of cellular ketone metabolic processGO:0010565660.132
Mouse
protein maturationGO:00516041760.130
organic acid biosynthetic processGO:0016053860.129
Mouse
positive regulation of cellular amine metabolic processGO:003324050.129
peptidyl amino acid modificationGO:00181933360.127
Mouse
negative regulation of protein processingGO:0010955790.127
regulation of triglyceride metabolic processGO:0090207170.126
Mouse
hexose biosynthetic processGO:0019319390.125
Mouse
negative regulation of hydrolase activityGO:0051346710.124
protein processingGO:00164851630.121
regulation of fatty acid metabolic processGO:0019217280.120
Mouse
regulation of protein maturationGO:1903317960.119
glycoprotein metabolic processGO:00091001160.119
extracellular structure organizationGO:00430621480.119
Mouse
regulation of inflammatory responseGO:00507271470.118
Mouse
glucose metabolic processGO:0006006920.117
Mouse
protein secretionGO:00093061110.117
Mouse
monocarboxylic acid metabolic processGO:00327871910.116
Mouse
regulation of peptidase activityGO:0052547960.115
regulation of cellular carbohydrate metabolic processGO:0010675750.110
Mouse
regulation of endopeptidase activityGO:0052548890.110
fatty acid biosynthetic processGO:0006633410.109
Mouse
cellular carbohydrate metabolic processGO:00442621190.106
Mouse
inflammatory responseGO:00069542440.106
Mouse Rat
hormone metabolic processGO:0042445860.105
Mouse
carbohydrate derivative biosynthetic processGO:19011371830.102
regulation of protein processingGO:0070613960.101
organic hydroxy compound metabolic processGO:19016152030.100
Mouse
negative regulation of endopeptidase activityGO:0010951440.100
response to peptideGO:19016521360.098
cellular response to organonitrogen compoundGO:00714171450.096
Mouse
regulation of cytokine productionGO:00018172660.095
Mouse
regulation of glucose metabolic processGO:0010906600.095
Mouse
negative regulation of molecular functionGO:00440922580.094
positive regulation of protein phosphorylationGO:00019342420.093
Mouse
negative regulation of proteolysisGO:0045861740.092
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.091
Mouse
regulation of defense responseGO:00313472330.091
Mouse
cell matrix adhesionGO:0007160680.090
Mouse
muscle cell differentiationGO:00426922610.089
Mouse
negative regulation of gluconeogenesisGO:004572190.089
Mouse
small molecule biosynthetic processGO:00442831320.085
Mouse
positive regulation of protein modification processGO:00314012990.085
Mouse
steroid metabolic processGO:00082021190.084
Mouse
urogenital system developmentGO:00016552610.083
Mouse
epithelial tube morphogenesisGO:00605623030.082
Mouse
negative regulation of cell proliferationGO:00082852960.082
Mouse
regulation of establishment of protein localizationGO:00702011810.082
Mouse
cellular ketone metabolic processGO:0042180840.081
Mouse
oxidation reduction processGO:00551143420.080
smooth muscle contractionGO:0006939440.079
Mouse
negative regulation of protein maturationGO:1903318790.078
regulation of transferase activityGO:00513382630.078
Mouse
regulation of kinase activityGO:00435492490.078
Mouse
inositol lipid mediated signalingGO:0048017410.077
Mouse
cellular response to insulin stimulusGO:0032869780.077
Mouse
monosaccharide metabolic processGO:00059961060.076
Mouse
monocarboxylic acid biosynthetic processGO:0072330610.076
Mouse
response to peptide hormoneGO:00434341270.074
cell substrate adhesionGO:00315891300.071
Mouse
extracellular matrix organizationGO:00301981470.071
Mouse
renal system developmentGO:00720012250.069
Mouse
mapk cascadeGO:00001652810.069
Mouse
regulation of proteolysisGO:00301621640.068
cellular response to hormone stimulusGO:00328701500.067
Mouse
spermatogenesisGO:00072832840.066
Mouse
regulation of protein localizationGO:00328802310.064
Mouse
female sex differentiationGO:0046660840.063
Mouse
regulation of carbohydrate metabolic processGO:0006109750.063
Mouse
muscle system processGO:00030121410.063
Mouse
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:0001991130.062
Mouse
blood circulationGO:00080151950.062
Mouse
renal tubule developmentGO:0061326870.061
Mouse
regulation of protein kinase activityGO:00458592320.061
Mouse
negative regulation of cellular carbohydrate metabolic processGO:0010677190.059
Mouse
regulation of mapk cascadeGO:00434082480.059
Mouse
ovulation cycleGO:0042698590.058
Mouse
nephron morphogenesisGO:0072028690.058
Mouse
rhythmic processGO:00485111740.057
Mouse
glucocorticoid metabolic processGO:000821190.057
Mouse
regulation of protein transportGO:00512231630.057
Mouse
response to insulinGO:00328681000.057
Mouse
cellular response to peptide hormone stimulusGO:0071375920.057
Mouse
circulatory system processGO:00030131970.056
Mouse
cellular response to peptideGO:1901653920.056
Mouse
cell adhesionGO:00071553290.055
Mouse
negative regulation of peptidase activityGO:0010466460.055
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.055
Mouse
regulation of tube sizeGO:0035150570.055
Mouse
regulation of protein secretionGO:0050708820.055
Mouse
cytokine productionGO:00018163190.055
Mouse
peptidyl serine modificationGO:0018209830.054
Mouse
response to acid chemicalGO:00011011110.054
Rat
female gonad developmentGO:0008585710.053
Mouse
renal system processGO:0003014480.053
Mouse
regulation of blood vessel sizeGO:0050880560.053
Mouse
nephron epithelium developmentGO:0072009920.053
Mouse
phosphatidylinositol 3 kinase signalingGO:0014065360.052
Mouse
cytokine secretionGO:0050663720.052
Mouse
nephron epithelium morphogenesisGO:0072088680.052
Mouse
positive regulation of transferase activityGO:00513471670.051
Mouse
response to organic cyclic compoundGO:00140701980.051
Rat
regulation of hormone levelsGO:00108172110.051
Mouse
positive regulation of protein transportGO:0051222930.051
Mouse
regulation of protein serine threonine kinase activityGO:00719001570.051
Mouse
carbohydrate biosynthetic processGO:0016051740.051
Mouse
response to molecule of bacterial originGO:00022371430.051
Rat
positive regulation of kinase activityGO:00336741550.050
Mouse
ras protein signal transductionGO:0007265770.050
mesonephric tubule developmentGO:0072164940.050
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.050
negative regulation of neuron deathGO:1901215980.050
Mouse
regulation of secretionGO:00510462740.050
Mouse
ureteric bud morphogenesisGO:0060675620.049
Mouse
vascular process in circulatory systemGO:0003018620.049
Mouse
positive regulation of secretionGO:00510471300.049
Mouse
development of primary female sexual characteristicsGO:0046545730.049
Mouse
kidney developmentGO:00018222130.049
Mouse
nephron developmentGO:00720061090.049
Mouse
regulation of secretion by cellGO:19035302490.047
Mouse
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199960.047
Mouse
astrocyte developmentGO:0014002120.047
Mouse
response to inorganic substanceGO:0010035960.047
Rat
monosaccharide biosynthetic processGO:0046364440.046
Mouse
reactive nitrogen species metabolic processGO:200105700.046
epithelial cell developmentGO:00020641590.046
Mouse
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.046
Mouse
gliogenesisGO:00420631410.046
Mouse
positive regulation of lipid biosynthetic processGO:0046889180.046
Mouse
multicellular organism growthGO:00352641610.046
Mouse
response to organonitrogen compoundGO:00102432460.046
positive regulation of protein kinase activityGO:00458601440.045
Mouse
endocrine processGO:0050886390.045
Mouse
nik nf kappab signalingGO:0038061140.044
Mouse
negative regulation of carbohydrate metabolic processGO:0045912190.044
Mouse
regulation of steroid metabolic processGO:0019218390.044
Mouse
negative regulation of neuron apoptotic processGO:0043524920.043
Mouse
immune effector processGO:00022523210.042
response to lipopolysaccharideGO:00324961280.041
Rat
kidney epithelium developmentGO:00720731210.041
Mouse
establishment of blood nerve barrierGO:000806530.041
Mouse
branching involved in ureteric bud morphogenesisGO:0001658560.041
Mouse
glycoprotein biosynthetic processGO:0009101890.041
positive regulation of cytokine secretionGO:0050715410.041
Mouse
mesonephros developmentGO:0001823970.040
Mouse
positive regulation of secretion by cellGO:19035321140.040
Mouse
neuron deathGO:00709971540.039
Mouse
regulation of neuron deathGO:19012141340.039
Mouse
response to decreased oxygen levelsGO:0036293590.039
Rat
kidney morphogenesisGO:0060993830.039
Mouse
endothelial cell developmentGO:0001885200.039
Mouse
regulation of anatomical structure sizeGO:00900661780.039
Mouse
positive regulation of growthGO:00459271040.038
Mouse
neuron apoptotic processGO:00514021420.038
Mouse
gluconeogenesisGO:0006094390.038
Mouse
positive regulation of cytokine productionGO:00018191740.037
Mouse
gonad developmentGO:00084061410.037
Mouse
regulation of cell activationGO:00508652890.037
regulation of cytokine secretionGO:0050707610.036
Mouse
positive regulation of blood pressureGO:0045777210.036
Mouse
feeding behaviorGO:0007631620.036
Mouse
endothelial cell differentiationGO:0045446410.035
Mouse
maintenance of locationGO:0051235890.035
cation homeostasisGO:00550802120.035
phasic smooth muscle contractionGO:001482180.035
Mouse
metal ion homeostasisGO:00550651890.035
regulation of carbohydrate biosynthetic processGO:0043255400.035
Mouse
cation transportGO:00068123990.034
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.034
Mouse
regulation of systemic arterial blood pressure by renin angiotensinGO:0003081200.034
Mouse
response to metal ionGO:0010038470.034
Rat
regulation of lipid biosynthetic processGO:0046890540.034
Mouse
regulation of neuron apoptotic processGO:00435231220.033
Mouse
neurological system process involved in regulation of systemic arterial blood pressureGO:0001976180.033
Mouse
vasoconstrictionGO:0042310270.033
Mouse
wound healingGO:00420601570.032
ureteric bud developmentGO:0001657940.031
Mouse
peptidyl serine phosphorylationGO:0018105740.031
Mouse
lipid localizationGO:00108761260.031
transmembrane transportGO:00550854120.031
regulation of blood vessel size by renin angiotensinGO:000203450.031
Mouse
response to steroid hormoneGO:0048545560.030
Rat
astrocyte differentiationGO:0048708430.030
Mouse
regulation of response to woundingGO:19030341890.030
Mouse
positive regulation of protein secretionGO:0050714520.029
Mouse
single organismal cell cell adhesionGO:00163371310.029
renal system process involved in regulation of systemic arterial blood pressureGO:0003071150.029
Mouse
regulation of systemic arterial blood pressure by hormoneGO:0001990250.029
Mouse
blood vessel morphogenesisGO:00485142850.029
branching morphogenesis of an epithelial tubeGO:00487541590.029
Mouse
cell type specific apoptotic processGO:00972852680.028
Mouse
ovulationGO:0030728150.027
Mouse
nucleoside phosphate metabolic processGO:00067533380.027
cellular homeostasisGO:00197252400.026
macromolecule catabolic processGO:00090572810.026
cellular chemical homeostasisGO:00550822150.026
regulation of cellular catabolic processGO:00313292420.026
positive regulation of protein serine threonine kinase activityGO:00719021060.026
Mouse
nucleobase containing small molecule metabolic processGO:00550863520.025
aromatic compound catabolic processGO:00194392860.025
glial cell developmentGO:0021782540.025
Mouse
peristalsisGO:003043280.025
Mouse
innate immune responseGO:00450871570.025
regulation of cellular response to insulin stimulusGO:1900076300.025
Mouse
cellular response to cytokine stimulusGO:00713451890.024
small gtpase mediated signal transductionGO:0007264970.024
regulation of lipid metabolic processGO:00192161180.024
Mouse
nucleotide metabolic processGO:00091173320.024
organic cyclic compound catabolic processGO:19013612950.024
regulation of organ growthGO:0046620610.024
Mouse
nitrogen compound transportGO:00717052710.024
ovulation from ovarian follicleGO:000154290.024
Mouse
regulation of nik nf kappab signalingGO:1901222100.023
Mouse
response to transition metal nanoparticleGO:1990267110.023
Rat
purine ribonucleoside metabolic processGO:00461282410.023
single organism cell adhesionGO:00986021560.023
heterocycle catabolic processGO:00467002800.023
adaptive immune responseGO:00022501550.023
camera type eye developmentGO:00430102660.023
regulation of system processGO:00440572000.023
g protein coupled receptor signaling pathwayGO:00071862430.023
response to estrogenGO:0043627240.023
Rat
cellular divalent inorganic cation homeostasisGO:00725031270.023
negative regulation of phospholipase activityGO:001051940.023
regulation of blood volume by renin angiotensinGO:000201670.022
Mouse
purine nucleotide metabolic processGO:00061633020.022
phosphatidylinositol mediated signalingGO:0048015410.022
Mouse
cellular nitrogen compound catabolic processGO:00442702800.022
regulation of cell adhesionGO:00301551540.022
ribose phosphate metabolic processGO:00196932910.021
divalent inorganic cation homeostasisGO:00725071380.021
reactive oxygen species metabolic processGO:0072593840.021
angiogenesisGO:00015252010.021
negative regulation of cellular amine metabolic processGO:003323910.021
sensory perceptionGO:00076002450.021
nucleoside phosphate catabolic processGO:19012922220.021
peripheral nervous system developmentGO:0007422530.021
Mouse
regulation of organelle organizationGO:00330432890.021
posttranscriptional regulation of gene expressionGO:00106081550.021
skeletal system developmentGO:00015013560.020
rho protein signal transductionGO:0007266320.020
carbohydrate derivative catabolic processGO:19011362310.020
organonitrogen compound catabolic processGO:19015652640.020
positive regulation of systemic arterial blood pressureGO:000308490.020
Mouse
female gamete generationGO:0007292740.020
Mouse
glycosyl compound metabolic processGO:19016572460.020
positive regulation of hydrolase activityGO:00513451480.020
morphogenesis of a branching structureGO:00017632030.020
Mouse
multicellular organismal homeostasisGO:00488711640.020
striated muscle tissue developmentGO:00147062930.020
nucleoside triphosphate metabolic processGO:00091412300.020
regulation of reactive oxygen species metabolic processGO:2000377400.020
sequestering of calcium ionGO:0051208180.020
gland developmentGO:00487323300.020
response to alcoholGO:0097305480.020
Rat
regulation of blood pressureGO:0008217930.020
Mouse
response to oxygen levelsGO:0070482620.020
Rat
cellular metal ion homeostasisGO:00068751510.020
myeloid cell differentiationGO:00300992330.019
cytoplasmic transportGO:00164822340.019
positive regulation of programmed cell deathGO:00430682180.019
sulfur compound metabolic processGO:00067901000.019
apoptotic signaling pathwayGO:00971903060.019
muscle tissue developmentGO:00605373080.019
positive regulation of reactive oxygen species biosynthetic processGO:190342820.019
cellular ion homeostasisGO:00068731650.019
insulin receptor signaling pathwayGO:0008286490.019
Mouse
muscle cell proliferationGO:0033002520.019
Mouse
organonitrogen compound biosynthetic processGO:19015661920.019
anatomical structure homeostasisGO:00602491450.019
amide transportGO:00428861380.018
protein catabolic processGO:00301632210.018
regulation of body fluid levelsGO:00508781620.018
nucleotide catabolic processGO:00091662170.018
excretionGO:0007588220.018
Mouse
positive regulation of cell deathGO:00109422240.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
ossificationGO:00015032160.018
organophosphate catabolic processGO:00464342320.018
cell growthGO:00160491300.018
hematopoietic progenitor cell differentiationGO:00022441430.017
ion transmembrane transportGO:00342203610.017
epidermis developmentGO:00085441870.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.017
purine nucleoside triphosphate metabolic processGO:00091442260.017
positive regulation of cellular response to insulin stimulusGO:190007890.017
Mouse
positive regulation of apoptotic processGO:00430652170.017
reactive oxygen species biosynthetic processGO:190340980.017
ribonucleotide metabolic processGO:00092592910.017
purine nucleotide catabolic processGO:00061952110.017
purine containing compound metabolic processGO:00725213110.017
regulation of ion transportGO:00432692150.017
synaptic transmissionGO:00072683290.017
response to temperature stimulusGO:0009266550.017
Mouse
regulation of vesicle mediated transportGO:00606271390.017
cellular calcium ion homeostasisGO:00068741190.017
leukocyte differentiationGO:00025213420.017
hormone secretionGO:00468791280.016
lymphocyte mediated immunityGO:00024491390.016
carbohydrate homeostasisGO:00335001280.016
purine ribonucleotide metabolic processGO:00091502900.016
purine nucleoside metabolic processGO:00422782410.016
purine ribonucleoside catabolic processGO:00461302050.016
respiratory system developmentGO:00605411900.016
positive regulation of mapk cascadeGO:00434101700.016
Mouse
regulation of membrane potentialGO:00423911920.016
glial cell differentiationGO:00100011310.016
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.016
renal tubule morphogenesisGO:0061333720.016
Mouse
male gamete generationGO:00482322850.016
Mouse
glucose homeostasisGO:00425931280.016
positive regulation of cell developmentGO:00107202370.016
fat cell differentiationGO:00454441600.016
chemotaxisGO:00069352470.016
endothelium developmentGO:0003158450.016
Mouse
ribonucleoside metabolic processGO:00091192450.016
cellular response to cadmium ionGO:007127630.016
ribonucleoside catabolic processGO:00424542060.016
positive regulation of organ growthGO:0046622290.016
Mouse
regulation of ras protein signal transductionGO:00465781140.016
organelle localizationGO:00516401790.015
nucleoside catabolic processGO:00091642060.015
response to coldGO:0009409190.015
Mouse
cognitionGO:00508901490.015
regulation of lymphocyte activationGO:00512492400.015
cellular response to dna damage stimulusGO:00069742070.015
purine nucleoside triphosphate catabolic processGO:00091462030.015
cation transmembrane transportGO:00986552660.015
glycosyl compound catabolic processGO:19016582060.015
positive regulation of reactive oxygen species metabolic processGO:2000379110.015
endocytosisGO:00068971680.015
regulation of cell motilityGO:20001452360.015
ribonucleotide catabolic processGO:00092612080.015
positive regulation of immune effector processGO:00026991070.015
divalent inorganic cation transportGO:00725111780.015
regulation of vasculature developmentGO:1901342880.014
fat soluble vitamin biosynthetic processGO:004236240.014
cellular macromolecule catabolic processGO:00442652060.014
transition metal ion homeostasisGO:0055076540.014
meiotic cell cycleGO:00513211220.014
nucleoside metabolic processGO:00091162460.014
calcium ion transportGO:00068161590.014
sequestering of metal ionGO:0051238190.014
cellular response to lipidGO:00713961450.014
small molecule catabolic processGO:0044282710.014
sensory organ morphogenesisGO:00905962420.014
purine nucleoside catabolic processGO:00061522050.014
cellular response to growth factor stimulusGO:00713631970.014
purine ribonucleotide catabolic processGO:00091542080.014
muscle contractionGO:00069361010.014
Mouse
regulation of cellular component biogenesisGO:00440871810.014
lymphocyte differentiationGO:00300982420.014
negative regulation of cellular amino acid metabolic processGO:004576300.014
positive regulation of lipid metabolic processGO:0045834400.014
Mouse
membrane organizationGO:00610242450.014
response to nutrient levelsGO:00316671090.014
protein oligomerizationGO:0051259670.014
regulation of cell cycleGO:00517262810.014
regulation of apoptotic signaling pathwayGO:20012331970.013
developmental maturationGO:00217001930.013
homeostasis of number of cellsGO:00488722100.013
retina development in camera type eyeGO:00600411190.013
negative regulation of intracellular signal transductionGO:19025321670.013
positive regulation of cellular catabolic processGO:00313311480.013
inorganic cation transmembrane transportGO:00986622070.013
multicellular organismal signalingGO:0035637910.013
cellular lipid catabolic processGO:0044242520.013
coagulationGO:0050817780.013
cellular response to external stimulusGO:0071496880.013
intracellular protein transportGO:00068862040.013
regulation of reactive oxygen species biosynthetic processGO:190342620.013
lateral inhibitionGO:004633110.013
forebrain developmentGO:00309003020.013
negative regulation of immune system processGO:00026832090.013
divalent metal ion transportGO:00708381720.013
cellular protein complex assemblyGO:00436231160.013
purine containing compound catabolic processGO:00725232130.013
organ regenerationGO:003110020.013
peptide transportGO:00158331330.013
protein modification by small protein conjugation or removalGO:00706472070.013
cellular response to inorganic substanceGO:0071241370.013
regulation of homeostatic processGO:00328441820.013
blood coagulationGO:0007596760.013
response to stilbenoidGO:0035634220.013
organic hydroxy compound transportGO:0015850930.013
dna metabolic processGO:00062593030.013
regulation of cellular component sizeGO:00325351210.013
t cell activationGO:00421102890.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
generation of precursor metabolites and energyGO:00060911030.013
regulation of interleukin 8 productionGO:003267730.013
sulfur compound biosynthetic processGO:0044272370.013
response to hypoxiaGO:0001666580.013
Rat
learning or memoryGO:00076111480.013
regulation of intracellular transportGO:00323861590.013
anion transportGO:00068201770.013
leukocyte mediated immunityGO:00024431740.013
regulation of action potentialGO:009890040.013
production of molecular mediator of immune responseGO:00024401030.012
response to testosteroneGO:003357430.012
locomotory behaviorGO:00076261950.012
positive regulation of cell adhesionGO:0045785800.012
drinking behaviorGO:004275650.012
Mouse
multi multicellular organism processGO:00447061090.012
meiotic nuclear divisionGO:00071261150.012
positive regulation of fatty acid oxidationGO:004632140.012
nucleoside triphosphate catabolic processGO:00091432050.012
regulation of leukocyte mediated immunityGO:00027031040.012
cellular response to organic cyclic compoundGO:0071407870.012
protein modification by small protein conjugationGO:00324461870.012
peptide secretionGO:00027901140.012
positive regulation of cell activationGO:00508671580.012
extrinsic apoptotic signaling pathwayGO:00971911260.012
regulation of cell migrationGO:00303342190.012
protein localization to organelleGO:00333651850.012
axonogenesisGO:00074092740.012
calcium ion homeostasisGO:00550741270.012
negative regulation of cellular component organizationGO:00511291940.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.012
cofactor transportGO:005118140.012
positive regulation of purine nucleotide metabolic processGO:19005441140.012
olfactory learningGO:000835520.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.012
epithelial cell proliferationGO:00506731740.012
cellular response to extracellular stimulusGO:0031668810.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
regulation of cellular response to growth factor stimulusGO:0090287820.012
organ growthGO:00352651170.012
Mouse
response to radiationGO:00093141650.012
positive regulation of nervous system developmentGO:00519622210.012
cytokine mediated signaling pathwayGO:00192211150.011
negative regulation of protein modification processGO:00314001630.011
porphyrin containing compound metabolic processGO:0006778220.011
organic anion transportGO:00157111370.011
inter male aggressive behaviorGO:000212130.011
membrane lipid metabolic processGO:0006643530.011
lipid transportGO:0006869980.011
regulation of hormone secretionGO:0046883880.011
negative regulation of response to woundingGO:1903035770.011

Serpina1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
alpha 1 antitrypsin deficiencyDOID:1337200.680
Human
plasma protein metabolism diseaseDOID:234500.680
Human
inherited metabolic disorderDOID:65500.680
Human
disease of metabolismDOID:001466700.680
Human
immune system diseaseDOID:291400.059
hematopoietic system diseaseDOID:7400.059
disease of anatomical entityDOID:700.059
nervous system diseaseDOID:86300.029
blood coagulation diseaseDOID:124700.019
inherited blood coagulation diseaseDOID:221400.018
musculoskeletal system diseaseDOID:1700.014
connective tissue diseaseDOID:6500.014
vascular diseaseDOID:17800.014
cardiovascular system diseaseDOID:128700.014
acquired metabolic diseaseDOID:006015800.013
primary immunodeficiency diseaseDOID:61200.012