Mus musculus

50 known processes

Palb2

partner and localizer of BRCA2

(Aliases: BC066140,4732427B05)

Palb2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.315
cellular response to dna damage stimulusGO:00069742070.194
dna repairGO:00062811070.193
meiotic cell cycle processGO:1903046770.127
dna recombinationGO:0006310920.120
double strand break repairGO:0006302480.108
meiotic nuclear divisionGO:00071261150.078
organelle fissionGO:00482851700.067
chromosome organization involved in meiosisGO:0070192390.064
purine containing compound metabolic processGO:00725213110.062
regulation of cell cycleGO:00517262810.058
nuclear divisionGO:00002801580.057
cellular amino acid metabolic processGO:00065201030.057
organic cyclic compound catabolic processGO:19013612950.056
purine ribonucleoside metabolic processGO:00461282410.056
nucleobase containing small molecule metabolic processGO:00550863520.052
regulation of organelle organizationGO:00330432890.049
amine metabolic processGO:0009308450.048
recombinational repairGO:0000725210.047
response to radiationGO:00093141650.046
meiotic cell cycleGO:00513211220.045
regulation of cellular amino acid metabolic processGO:000652150.045
glycosyl compound metabolic processGO:19016572460.042
cellular amine metabolic processGO:0044106440.042
nucleoside monophosphate metabolic processGO:0009123850.042
ribonucleotide metabolic processGO:00092592910.041
ribose phosphate metabolic processGO:00196932910.040
purine nucleoside catabolic processGO:00061522050.040
cellular macromolecule catabolic processGO:00442652060.039
nucleoside metabolic processGO:00091162460.039
atp metabolic processGO:0046034750.039
cellular nitrogen compound catabolic processGO:00442702800.039
organophosphate catabolic processGO:00464342320.038
regulation of cellular amine metabolic processGO:0033238200.038
glycosyl compound catabolic processGO:19016582060.038
chromosome segregationGO:0007059480.038
protein catabolic processGO:00301632210.037
purine ribonucleoside triphosphate metabolic processGO:00092052200.036
purine ribonucleotide metabolic processGO:00091502900.036
purine nucleoside metabolic processGO:00422782410.036
aromatic compound catabolic processGO:00194392860.036
purine nucleoside triphosphate metabolic processGO:00091442260.036
atp catabolic processGO:0006200550.036
ribonucleoside triphosphate catabolic processGO:00092031990.036
regulation of cellular ketone metabolic processGO:0010565660.035
nucleoside phosphate metabolic processGO:00067533380.035
purine nucleotide metabolic processGO:00061633020.035
purine ribonucleoside monophosphate metabolic processGO:0009167800.034
carbohydrate derivative catabolic processGO:19011362310.034
intrinsic apoptotic signaling pathwayGO:00971931320.034
purine nucleoside triphosphate catabolic processGO:00091462030.034
nucleoside triphosphate catabolic processGO:00091432050.033
purine containing compound catabolic processGO:00725232130.032
male gamete generationGO:00482322850.032
cellular ketone metabolic processGO:0042180840.031
ribonucleoside metabolic processGO:00091192450.031
regulation of cell cycle processGO:00105641600.031
negative regulation of cellular protein metabolic processGO:00322692470.031
purine ribonucleoside catabolic processGO:00461302050.031
heterocycle catabolic processGO:00467002800.031
purine ribonucleotide catabolic processGO:00091542080.030
chromatin modificationGO:00165681870.030
chromatin organizationGO:00063252060.030
purine ribonucleoside triphosphate catabolic processGO:00092071990.029
ribonucleoside catabolic processGO:00424542060.029
nucleoside catabolic processGO:00091642060.029
ribonucleoside triphosphate metabolic processGO:00091992200.029
cell divisionGO:00513011200.028
nucleoside phosphate catabolic processGO:19012922220.028
negative regulation of protein metabolic processGO:00512482820.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
nucleoside triphosphate metabolic processGO:00091412300.027
positive regulation of cellular amine metabolic processGO:003324050.027
nucleotide metabolic processGO:00091173320.027
negative regulation of cellular component organizationGO:00511291940.026
regulation of cellular catabolic processGO:00313292420.026
purine nucleotide catabolic processGO:00061952110.026
spermatogenesisGO:00072832840.026
cell cycle checkpointGO:0000075470.026
nucleotide catabolic processGO:00091662170.026
protein ubiquitinationGO:00165671710.025
protein modification by small protein conjugation or removalGO:00706472070.024
response to organonitrogen compoundGO:00102432460.024
ribonucleoside monophosphate catabolic processGO:0009158570.024
double strand break repair via homologous recombinationGO:0000724210.024
meiosis iGO:0007127600.024
methylationGO:00322591340.023
regulation of mitotic cell cycle phase transitionGO:1901990730.023
ribonucleotide catabolic processGO:00092612080.023
regulation of cell cycle phase transitionGO:1901987770.023
macromolecule methylationGO:00434141200.023
macromolecule catabolic processGO:00090572810.023
organonitrogen compound catabolic processGO:19015652640.022
spermatid developmentGO:00072861080.022
nucleoside monophosphate catabolic processGO:0009125590.022
cellular protein catabolic processGO:00442571550.021
anatomical structure homeostasisGO:00602491450.021
peptidyl amino acid modificationGO:00181933360.021
mitotic cell cycleGO:00002781950.021
purine nucleoside monophosphate metabolic processGO:0009126810.021
response to ionizing radiationGO:0010212420.020
regulation of chromosome organizationGO:0033044830.020
cellular response to organonitrogen compoundGO:00714171450.020
regulation of mitotic cell cycleGO:00073461260.020
negative regulation of cell cycleGO:00457861230.019
germ cell developmentGO:00072811850.019
purine nucleoside monophosphate catabolic processGO:0009128580.019
lipid biosynthetic processGO:00086101790.019
immune effector processGO:00022523210.019
oxidation reduction processGO:00551143420.018
cation transportGO:00068123990.018
protein maturationGO:00516041760.018
cellular lipid metabolic processGO:00442553230.018
positive regulation of programmed cell deathGO:00430682180.018
proteolysis involved in cellular protein catabolic processGO:00516031470.018
regulation of proteolysisGO:00301621640.018
cellular response to cytokine stimulusGO:00713451890.017
regulation of lymphocyte activationGO:00512492400.017
regulation of membrane potentialGO:00423911920.017
membrane organizationGO:00610242450.017
ubiquitin dependent protein catabolic processGO:00065111290.016
cell type specific apoptotic processGO:00972852680.016
regulation of cellular response to stressGO:00801351590.016
spermatid differentiationGO:00485151150.016
regulation of transferase activityGO:00513382630.016
protein processingGO:00164851630.016
production of molecular mediator of immune responseGO:00024401030.016
negative regulation of cell proliferationGO:00082852960.016
multicellular organismal signalingGO:0035637910.016
sister chromatid segregationGO:0000819200.016
positive regulation of protein modification processGO:00314012990.016
regulation of cell activationGO:00508652890.015
dna dependent dna replication maintenance of fidelityGO:004500530.015
ion transmembrane transportGO:00342203610.015
histone modificationGO:00165701590.015
cytokine productionGO:00018163190.015
response to organic cyclic compoundGO:00140701980.015
regulation of apoptotic signaling pathwayGO:20012331970.015
cytoplasmic transportGO:00164822340.015
ribonucleoside monophosphate metabolic processGO:0009161800.015
lateral inhibitionGO:004633110.015
t cell activationGO:00421102890.015
positive regulation of cell deathGO:00109422240.015
covalent chromatin modificationGO:00165691630.015
regulation of defense responseGO:00313472330.015
purine ribonucleoside monophosphate catabolic processGO:0009169570.014
b cell activationGO:00421131610.014
cell fate commitmentGO:00451652100.014
leukocyte differentiationGO:00025213420.014
protein localization to organelleGO:00333651850.014
small gtpase mediated signal transductionGO:0007264970.014
transmembrane transportGO:00550854120.014
nitrogen compound transportGO:00717052710.014
protein modification by small protein conjugationGO:00324461870.014
positive regulation of apoptotic processGO:00430652170.014
response to light stimulusGO:00094161350.014
protein methylationGO:0006479810.014
cellular homeostasisGO:00197252400.014
regulation of secretionGO:00510462740.014
gland developmentGO:00487323300.014
regulation of sister chromatid segregationGO:0033045130.014
female gamete generationGO:0007292740.013
positive regulation of cell developmentGO:00107202370.013
negative regulation of cellular catabolic processGO:0031330470.013
regulation of nuclear divisionGO:0051783560.013
microtubule based processGO:00070172360.013
microtubule cytoskeleton organizationGO:00002261570.013
regulation of cytokine productionGO:00018172660.013
lymphocyte mediated immunityGO:00024491390.013
mitotic nuclear divisionGO:0007067480.013
developmental maturationGO:00217001930.013
multicellular organism growthGO:00352641610.013
lymphocyte differentiationGO:00300982420.013
monocarboxylic acid metabolic processGO:00327871910.012
apoptotic signaling pathwayGO:00971903060.012
regulation of cell divisionGO:0051302760.012
cell adhesionGO:00071553290.012
reactive oxygen species metabolic processGO:0072593840.012
myeloid cell differentiationGO:00300992330.012
regulation of protein maturationGO:1903317960.012
sensory perceptionGO:00076002450.012
positive regulation of cell cycleGO:0045787920.012
nucleocytoplasmic transportGO:00069131390.012
intracellular protein transportGO:00068862040.012
gene silencingGO:0016458380.012
mitotic cell cycle processGO:19030471590.012
multicellular organismal homeostasisGO:00488711640.012
heterochromatin organizationGO:007082840.012
regulation of cellular component biogenesisGO:00440871810.012
leukocyte mediated immunityGO:00024431740.012
negative regulation of protein processingGO:0010955790.012
cation transmembrane transportGO:00986552660.011
negative regulation of transferase activityGO:0051348850.011
organic anion transportGO:00157111370.011
regulation of hydrolase activityGO:00513362460.011
rhythmic processGO:00485111740.011
negative regulation of nuclear divisionGO:0051784190.011
locomotory behaviorGO:00076261950.011
histone methylationGO:0016571710.011
negative regulation of molecular functionGO:00440922580.011
glucose homeostasisGO:00425931280.011
cellular response to gamma radiationGO:007148040.011
carbohydrate derivative biosynthetic processGO:19011371830.011
divalent inorganic cation transportGO:00725111780.011
protein alkylationGO:0008213810.011
response to extracellular stimulusGO:00099911270.011
inflammatory responseGO:00069542440.011
divalent metal ion transportGO:00708381720.011
regulation of histone modificationGO:0031056560.011
lymphocyte proliferationGO:00466511640.011
mapk cascadeGO:00001652810.011
cofactor metabolic processGO:0051186800.011
negative regulation of cell cycle processGO:0010948690.011
proteasomal protein catabolic processGO:0010498980.011
leukocyte activation involved in immune responseGO:00023661260.011
engulfment of apoptotic cellGO:004365230.011
regulation of mapk cascadeGO:00434082480.011
negative regulation of protein modification processGO:00314001630.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.011
negative regulation of dna replicationGO:000815640.011
regulation of dna recombinationGO:0000018340.011
action potentialGO:0001508780.011
response to acid chemicalGO:00011011110.011
cell cycle g1 s phase transitionGO:0044843570.011
cell activation involved in immune responseGO:00022631260.010
regulation of protein processingGO:0070613960.010
mitotic cell cycle checkpointGO:0007093310.010
hematopoietic progenitor cell differentiationGO:00022441430.010
adaptive immune responseGO:00022501550.010
gonad developmentGO:00084061410.010
regulation of secretion by cellGO:19035302490.010
ossificationGO:00015032160.010
negative regulation of protein maturationGO:1903318790.010
skeletal system developmentGO:00015013560.010
negative regulation of intracellular signal transductionGO:19025321670.010
camera type eye developmentGO:00430102660.010
chromosome separationGO:0051304140.010
forebrain developmentGO:00309003020.010
organic hydroxy compound metabolic processGO:19016152030.010
response to oxidative stressGO:00069791230.010
regulation of t cell activationGO:00508631700.010
negative regulation of mitotic cell cycle phase transitionGO:1901991450.010
cellular chemical homeostasisGO:00550822150.010
nuclear transportGO:00511691390.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of reactive oxygen species metabolic processGO:2000377400.010

Palb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.073
cancerDOID:16200.073
organ system cancerDOID:005068600.073
disease of anatomical entityDOID:700.034
immune system diseaseDOID:291400.034
aplastic anemiaDOID:1244900.034
bone marrow diseaseDOID:496100.034
anemiaDOID:235500.034
hematopoietic system diseaseDOID:7400.034
nervous system diseaseDOID:86300.022
thoracic cancerDOID:509300.016
congenital hypoplastic anemiaDOID:134200.015
breast cancerDOID:161200.014
gastrointestinal system cancerDOID:311900.014
large intestine cancerDOID:567200.012
intestinal cancerDOID:1015500.012
immune system cancerDOID:006008300.011
hematologic cancerDOID:253100.011
disease of metabolismDOID:001466700.010
central nervous system diseaseDOID:33100.010