Mus musculus

23 known processes

Psmb10

proteasome (prosome, macropain) subunit, beta type 10

(Aliases: Mecl1)

Psmb10 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antigen processing and presentation of exogenous antigenGO:0019884260.717
positive regulation of t cell mediated cytotoxicityGO:0001916150.654
antigen processing and presentationGO:0019882470.628
innate immune responseGO:00450871570.402
negative regulation of natural killer cell mediated immunityGO:000271650.368
antigen processing and presentation of peptide antigen via mhc class iGO:000247490.326
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.255
antigen processing and presentation of exogenous peptide antigenGO:0002478210.216
interspecies interaction between organismsGO:0044419830.186
regulation of t cell activationGO:00508631700.179
antigen processing and presentation of exogenous peptide antigen via mhc class ibGO:000247730.175
regulation of defense responseGO:00313472330.171
leukocyte mediated cytotoxicityGO:0001909620.160
t cell proliferationGO:00420981200.158
regulation of natural killer cell mediated cytotoxicityGO:0042269190.148
positive regulation of innate immune responseGO:0045089800.129
regulation of intracellular transportGO:00323861590.117
regulation of defense response to virus by hostGO:005069180.111
regulation of cellular ketone metabolic processGO:0010565660.103
regulation of type i interferon mediated signaling pathwayGO:006033870.100
positive regulation of proteolysisGO:0045862850.098
negative regulation of cell proliferationGO:00082852960.098
positive regulation of peptidase activityGO:0010952490.097
lymphocyte mediated immunityGO:00024491390.093
leukocyte proliferationGO:00706611720.087
fat cell differentiationGO:00454441600.080
ribose phosphate metabolic processGO:00196932910.076
cellular amine metabolic processGO:0044106440.076
regulation of myd88 independent toll like receptor signaling pathwayGO:003412710.076
carbohydrate derivative catabolic processGO:19011362310.075
cellular amino acid metabolic processGO:00065201030.074
cellular ketone metabolic processGO:0042180840.074
purine ribonucleotide catabolic processGO:00091542080.069
protein polymerizationGO:0051258570.069
peptide metabolic processGO:0006518460.068
regulation of endopeptidase activityGO:0052548890.068
regulation of proteolysisGO:00301621640.068
cation transportGO:00068123990.067
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988530.066
response to lipopolysaccharideGO:00324961280.063
intracellular protein transportGO:00068862040.062
positive regulation of hydrolase activityGO:00513451480.060
cellular chemical homeostasisGO:00550822150.060
myosin filament organizationGO:003103330.059
negative regulation of molecular functionGO:00440922580.058
t cell activationGO:00421102890.057
regulation of peptidase activityGO:0052547960.055
actin filament polymerizationGO:0030041440.055
regulation of hormone levelsGO:00108172110.053
regulation of hydrolase activityGO:00513362460.053
female sex differentiationGO:0046660840.052
gland developmentGO:00487323300.051
arp2 3 complex mediated actin nucleationGO:003431430.050
negative regulation of protein modification processGO:00314001630.049
epidermis developmentGO:00085441870.049
negative regulation of immune system processGO:00026832090.049
organic cyclic compound catabolic processGO:19013612950.048
glycosyl compound metabolic processGO:19016572460.047
cytoplasmic transportGO:00164822340.047
natural killer cell mediated immunityGO:0002228290.046
leukocyte differentiationGO:00025213420.046
nucleobase containing small molecule metabolic processGO:00550863520.044
regulation of cellular component biogenesisGO:00440871810.044
purine containing compound catabolic processGO:00725232130.044
positive regulation of cellular amino acid metabolic processGO:004576430.044
protein catabolic processGO:00301632210.042
Yeast
aromatic compound catabolic processGO:00194392860.042
regulation of leukocyte mediated cytotoxicityGO:0001910380.042
regulation of lymphocyte activationGO:00512492400.041
negative regulation of phosphorus metabolic processGO:00105631840.040
regulation of arp2 3 complex mediated actin nucleationGO:003431510.039
nucleotide catabolic processGO:00091662170.039
positive regulation of cellular amine metabolic processGO:003324050.039
rac protein signal transductionGO:0016601130.038
regulation of cellular amine metabolic processGO:0033238200.038
muscle tissue developmentGO:00605373080.038
cell adhesionGO:00071553290.038
metal ion homeostasisGO:00550651890.037
guanosine containing compound metabolic processGO:19010681440.037
cd8 positive alpha beta t cell proliferationGO:003574010.037
phagocytosisGO:0006909660.036
antigen processing and presentation of peptide antigenGO:0048002290.036
negative regulation of cellular protein metabolic processGO:00322692470.035
regulation of cytoplasmic transportGO:19036491120.035
negative regulation of cellular amine metabolic processGO:003323910.035
symbiosis encompassing mutualism through parasitismGO:0044403830.034
cellular response to growth factor stimulusGO:00713631970.034
uropod organizationGO:003279620.034
response to organonitrogen compoundGO:00102432460.034
cell fate commitmentGO:00451652100.034
positive regulation of cellular component biogenesisGO:0044089940.033
actin cytoskeleton organizationGO:00300362200.032
macromolecule catabolic processGO:00090572810.032
Yeast
regulation of cellular amino acid metabolic processGO:000652150.031
kidney developmentGO:00018222130.031
myeloid cell differentiationGO:00300992330.031
negative regulation of phosphorylationGO:00423261660.031
endocytosisGO:00068971680.030
myeloid cell homeostasisGO:00022621140.030
cellular metal ion homeostasisGO:00068751510.030
regulation of protein ubiquitinationGO:0031396520.030
positive regulation of lymphocyte activationGO:00512511400.029
cell substrate adhesionGO:00315891300.029
molting cycleGO:0042303900.029
calcium ion transportGO:00068161590.029
positive regulation of endopeptidase activityGO:0010950430.028
neuron deathGO:00709971540.027
regulation of t cell proliferationGO:0042129920.027
sequestering of metal ionGO:0051238190.027
regulation of cellular component sizeGO:00325351210.027
regulation of protein localizationGO:00328802310.027
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247640.026
cellular nitrogen compound catabolic processGO:00442702800.026
response to organic cyclic compoundGO:00140701980.026
response to radiationGO:00093141650.026
actin polymerization or depolymerizationGO:0008154540.026
cellular homeostasisGO:00197252400.026
cellular macromolecule catabolic processGO:00442652060.025
Yeast
heterocycle catabolic processGO:00467002800.025
regulation of neuron apoptotic processGO:00435231220.025
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.025
i kappab kinase nf kappab signalingGO:0007249850.025
histone modificationGO:00165701590.024
cellular ion homeostasisGO:00068731650.024
regulation of homeostatic processGO:00328441820.024
organelle assemblyGO:00709251770.024
regulation of cell motilityGO:20001452360.024
regulation of nucleotide metabolic processGO:00061401690.024
regulation of reactive oxygen species biosynthetic processGO:190342620.024
homeostasis of number of cellsGO:00488722100.023
regulation of lipid metabolic processGO:00192161180.023
regulation of myd88 dependent toll like receptor signaling pathwayGO:003412420.023
adaptive immune responseGO:00022501550.023
cellular response to cytokine stimulusGO:00713451890.023
protein localization to organelleGO:00333651850.023
regulation of protein complex assemblyGO:0043254830.023
sequestering of calcium ionGO:0051208180.023
protein ubiquitinationGO:00165671710.023
negative regulation of protein phosphorylationGO:00019331260.022
negative regulation of protein metabolic processGO:00512482820.022
response to protozoanGO:0001562280.021
defense response to virusGO:0051607680.021
germ cell developmentGO:00072811850.021
carbohydrate homeostasisGO:00335001280.021
antigen processing and presentation via mhc class ibGO:000247580.021
regulation of purine nucleotide metabolic processGO:19005421690.021
nucleoside phosphate metabolic processGO:00067533380.021
guanosine containing compound catabolic processGO:19010691440.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.021
amine metabolic processGO:0009308450.021
small gtpase mediated signal transductionGO:0007264970.020
myd88 independent toll like receptor signaling pathwayGO:000275630.020
apoptotic signaling pathwayGO:00971903060.020
response to light stimulusGO:00094161350.020
positive regulation of actin filament polymerizationGO:0030838260.020
response to inorganic substanceGO:0010035960.020
keratinocyte differentiationGO:0030216480.020
tube formationGO:00351481400.020
defense response to protozoanGO:0042832250.020
negative regulation of phosphate metabolic processGO:00459361840.019
nucleoside triphosphate metabolic processGO:00091412300.019
purine ribonucleoside triphosphate catabolic processGO:00092071990.019
extrinsic apoptotic signaling pathwayGO:00971911260.019
calcium ion transport into cytosolGO:0060402480.019
ras protein signal transductionGO:0007265770.019
negative regulation of defense response to virus by hostGO:005068910.019
oxidation reduction processGO:00551143420.019
negative regulation of innate immune responseGO:0045824170.018
regulation of calcium ion transport into cytosolGO:0010522310.018
nucleoside phosphate catabolic processGO:19012922220.018
purine ribonucleoside metabolic processGO:00461282410.018
skin developmentGO:00435882200.018
posttranscriptional regulation of gene expressionGO:00106081550.018
ribonucleoside triphosphate metabolic processGO:00091992200.018
sensory organ morphogenesisGO:00905962420.018
positive regulation of programmed cell deathGO:00430682180.018
response to growth factorGO:00708481980.018
positive regulation of t cell activationGO:00508701010.017
negative regulation of defense responseGO:0031348770.017
regulation of actin filament lengthGO:0030832450.017
maintenance of locationGO:0051235890.017
rna interferenceGO:001624620.017
positive regulation of apoptotic signaling pathwayGO:2001235950.017
regulation of actin filament based processGO:0032970990.017
regulation of organelle organizationGO:00330432890.017
defense response to other organismGO:00985421970.017
regulation of cell migrationGO:00303342190.017
negative regulation of vesicle fusionGO:003133910.017
regulation of cell activationGO:00508652890.017
t cell homeostasisGO:0043029350.017
peptidyl amino acid modificationGO:00181933360.017
cellular divalent inorganic cation homeostasisGO:00725031270.017
positive regulation of interferon alpha productionGO:003272740.017
regulation of actin polymerization or depolymerizationGO:0008064450.017
cellular response to dna damage stimulusGO:00069742070.017
Fly
peptidyl lysine methylationGO:0018022290.017
nucleotide metabolic processGO:00091173320.017
intracellular transport of virusGO:007573310.017
positive regulation of protein complex assemblyGO:0031334450.017
negative regulation of protein ubiquitinationGO:0031397190.017
inflammatory responseGO:00069542440.017
neuron apoptotic processGO:00514021420.016
cellular component disassembly involved in execution phase of apoptosisGO:000692190.016
purine nucleoside triphosphate catabolic processGO:00091462030.016
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336980.016
dna metabolic processGO:00062593030.016
progesterone metabolic processGO:004244840.016
tissue homeostasisGO:00018941150.016
gtp metabolic processGO:00460391440.016
t cell mediated immunityGO:0002456500.016
striated muscle myosin thick filament assemblyGO:007168810.016
cation homeostasisGO:00550802120.016
glycoprotein metabolic processGO:00091001160.016
transport of virusGO:004679410.016
protein localization to nucleusGO:00345041210.016
positive regulation of rig i signaling pathwayGO:190024610.016
leukocyte activation involved in immune responseGO:00023661260.016
g protein coupled receptor signaling pathwayGO:00071862430.016
organic hydroxy compound metabolic processGO:19016152030.016
cytokine productionGO:00018163190.016
nucleoside triphosphate catabolic processGO:00091432050.015
nuclear importGO:0051170950.015
central nervous system neuron differentiationGO:00219531620.015
mitochondrion organizationGO:00070051340.015
regulation of leukocyte proliferationGO:00706631210.015
ribonucleotide metabolic processGO:00092592910.015
nuclear transportGO:00511691390.015
protection from natural killer cell mediated cytotoxicityGO:004227020.015
type i interferon productionGO:0032606290.015
regulation of neuron deathGO:19012141340.015
protein modification by small protein conjugationGO:00324461870.015
intrinsic apoptotic signaling pathwayGO:00971931320.015
leukocyte mediated immunityGO:00024431740.015
regulation of actin filament polymerizationGO:0030833380.015
ribonucleoside catabolic processGO:00424542060.015
interleukin 1 productionGO:0032612310.015
regulation of lymphocyte proliferationGO:00506701170.015
cellular protein complex assemblyGO:00436231160.015
regulation of cytokine biosynthetic processGO:0042035590.014
cellular response to type i interferonGO:0071357100.014
type i interferon signaling pathwayGO:0060337100.014
glucose homeostasisGO:00425931280.014
t helper 17 cell lineage commitmentGO:007254040.014
iron ion import into cellGO:009745940.014
regulation of leukocyte differentiationGO:19021051590.014
reactive oxygen species metabolic processGO:0072593840.014
anatomical structure homeostasisGO:00602491450.014
striated muscle tissue developmentGO:00147062930.014
positive regulation of cytosolic calcium ion concentrationGO:0007204650.014
cytosolic calcium ion transportGO:0060401480.014
regulation of synaptic growth at neuromuscular junctionGO:000858240.014
monocarboxylic acid metabolic processGO:00327871910.014
response to peptideGO:19016521360.014
divalent inorganic cation transportGO:00725111780.014
regulation of metal ion transportGO:00109591060.014
regulation of actin nucleationGO:005112540.014
establishment of protein localization to organelleGO:00725941180.013
viral life cycleGO:0019058360.013
reactive nitrogen species metabolic processGO:200105700.013
actin filament organizationGO:00070151130.013
negative regulation of cellular component organizationGO:00511291940.013
purine ribonucleotide metabolic processGO:00091502900.013
hormone secretionGO:00468791280.013
protein targetingGO:00066051430.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of kinase activityGO:00336741550.013
positive regulation of leukocyte mediated immunityGO:0002705700.013
cell killingGO:0001906670.013
multicellular organism growthGO:00352641610.013
cellular lipid metabolic processGO:00442553230.013
regulation of dna templated transcription initiationGO:200014270.013
protein methylationGO:0006479810.013
positive regulation of interferon gamma productionGO:0032729390.013
carbohydrate metabolic processGO:00059752300.013
regulation of purine nucleotide catabolic processGO:00331211220.013
cell type specific apoptotic processGO:00972852680.013
positive regulation of organelle organizationGO:00106381280.013
regulation of t cell mediated cytotoxicityGO:0001914180.013
negative regulation of lymphocyte mediated immunityGO:0002707210.013
renal system developmentGO:00720012250.013
purine nucleoside catabolic processGO:00061522050.013
negative regulation of transferase activityGO:0051348850.013
chromatin organizationGO:00063252060.013
protein importGO:00170381010.013
negative regulation of kinase activityGO:0033673810.013
negative regulation of homeostatic processGO:0032845710.013
male gamete generationGO:00482322850.012
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:000229120.012
regulation of protein modification by small protein conjugation or removalGO:1903320570.012
positive regulation of tolerance induction dependent upon immune responseGO:000265410.012
regulation of bindingGO:00510981110.012
neural tube developmentGO:00219151600.012
regulation of anatomical structure sizeGO:00900661780.012
cellular response to peptideGO:1901653920.012
negative regulation of intracellular protein transportGO:0090317270.012
nitrogen compound transportGO:00717052710.012
cellular calcium ion homeostasisGO:00068741190.012
myosin filament assemblyGO:003103420.012
blood vessel morphogenesisGO:00485142850.012
lymphocyte proliferationGO:00466511640.012
calcium ion homeostasisGO:00550741270.012
regulation of protein kinase activityGO:00458592320.012
negative regulation of regulatory t cell differentiationGO:004559020.012
purine nucleotide biosynthetic processGO:0006164650.012
lymphocyte differentiationGO:00300982420.012
membrane organizationGO:00610242450.012
regulation of intracellular protein transportGO:0033157820.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
positive regulation of t cell proliferationGO:0042102520.012
ear developmentGO:00435832000.012
positive regulation of actin nucleationGO:005112730.012
lysosomal transportGO:0007041100.011
regulation of transferase activityGO:00513382630.011
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.011
cellular response to abiotic stimulusGO:0071214560.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
regulation of cytoskeleton organizationGO:00514931220.011
b cell mediated immunityGO:0019724710.011
lymphocyte activation involved in immune responseGO:0002285930.011
regulation of cell adhesionGO:00301551540.011
regulation of membrane potentialGO:00423911920.011
regulation of vesicle mediated transportGO:00606271390.011
purine nucleotide metabolic processGO:00061633020.011
deoxyribonucleotide catabolic processGO:000926450.011
plasma cell differentiationGO:000231730.011
divalent inorganic cation homeostasisGO:00725071380.011
sensory perceptionGO:00076002450.011
rhythmic processGO:00485111740.011
chromatin modificationGO:00165681870.011
positive regulation of type i interferon mediated signaling pathwayGO:006034040.011
protein modification by small protein conjugation or removalGO:00706472070.011
cellular response to organonitrogen compoundGO:00714171450.011
b cell activationGO:00421131610.011
negative regulation of neuron apoptotic processGO:0043524920.011
protein oligomerizationGO:0051259670.011
response to dsrnaGO:0043331300.011
regulation of lymphocyte mediated immunityGO:0002706840.011
positive regulation of cell migrationGO:00303351090.011
immune response regulating signaling pathwayGO:00027641250.011
epithelial tube formationGO:00721751300.011
regulation of cytokine productionGO:00018172660.011
regulation of kinase activityGO:00435492490.010
regulation of ion homeostasisGO:2000021640.010
epithelial cell proliferationGO:00506731740.010
immune effector processGO:00022523210.010
cellular response to interleukin 4GO:0071353210.010
extracellular matrix organizationGO:00301981470.010
translationGO:0006412930.010
neuromuscular processGO:0050905990.010
gonad developmentGO:00084061410.010
leukocyte homeostasisGO:0001776790.010
female gonad developmentGO:0008585710.010
negative regulation of organelle organizationGO:0010639900.010
purine ribonucleoside triphosphate metabolic processGO:00092052200.010
embryonic epithelial tube formationGO:00018381300.010
locomotory behaviorGO:00076261950.010
synaptic transmissionGO:00072683290.010
protein localization to plasma membraneGO:0072659570.010
response to peptide hormoneGO:00434341270.010
regulation of peptidyl serine phosphorylationGO:0033135390.010
positive regulation of leukocyte proliferationGO:0070665730.010
sulfur compound metabolic processGO:00067901000.010
covalent chromatin modificationGO:00165691630.010
antigen processing and presentation of exogenous peptide antigen via mhc class iGO:004259060.010
regulation of protein heterodimerization activityGO:004349720.010
regulation of tolerance induction dependent upon immune responseGO:000265210.010
establishment of protein localization to membraneGO:0090150540.010

Psmb10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.021
gastrointestinal system cancerDOID:311900.021
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
primary immunodeficiency diseaseDOID:61200.013
disease of anatomical entityDOID:700.013
immune system diseaseDOID:291400.013
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011
bone diseaseDOID:008000100.011
nervous system diseaseDOID:86300.010