Mus musculus

8 known processes

Klra8

killer cell lectin-like receptor, subfamily A, member 8

(Aliases: Ly49u<129>,Cmv1,Cmv-1,Ly49h)

Klra8 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
stimulatory c type lectin receptor signaling pathwayGO:000222320.226
innate immune responseGO:00450871570.183
positive regulation of cell killingGO:0031343330.177
response to lipopolysaccharideGO:00324961280.151
regulation of lymphocyte activationGO:00512492400.148
regulation of innate immune responseGO:0045088910.120
positive regulation of natural killer cell mediated immunityGO:0002717160.119
cell killingGO:0001906670.118
positive regulation of innate immune responseGO:0045089800.114
small gtpase mediated signal transductionGO:0007264970.112
cellular amino acid metabolic processGO:00065201030.103
immune effector processGO:00022523210.103
positive regulation of natural killer cell mediated cytotoxicityGO:0045954160.100
leukocyte mediated cytotoxicityGO:0001909620.097
cell recognitionGO:0008037830.095
natural killer cell activationGO:0030101440.093
myeloid cell differentiationGO:00300992330.092
regulation of membrane potentialGO:00423911920.091
detection of yeastGO:000187920.089
innate immune response activating cell surface receptor signaling pathwayGO:000222040.086
regulation of natural killer cell mediated immunityGO:0002715190.085
natural killer cell mediated immunityGO:0002228290.084
reactive nitrogen species metabolic processGO:200105700.081
immune response activating signal transductionGO:00027571160.075
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.072
activation of immune responseGO:00022531380.071
regulation of cell killingGO:0031341400.071
lymphocyte mediated immunityGO:00024491390.070
regulation of cytokine productionGO:00018172660.069
muscle tissue developmentGO:00605373080.066
cytokine productionGO:00018163190.064
regulation of leukocyte mediated immunityGO:00027031040.063
negative regulation of immune system processGO:00026832090.063
positive regulation of lymphocyte mediated immunityGO:0002708620.062
positive regulation of reactive oxygen species metabolic processGO:2000379110.062
immune response regulating signaling pathwayGO:00027641250.061
cellular response to lipopolysaccharideGO:0071222770.060
regulation of cell activationGO:00508652890.058
immune response activating cell surface receptor signaling pathwayGO:0002429720.058
regulation of leukocyte mediated cytotoxicityGO:0001910380.058
response to molecule of bacterial originGO:00022371430.057
negative regulation of immune effector processGO:0002698550.057
natural killer cell mediated cytotoxicityGO:0042267290.057
defense response to gram positive bacteriumGO:0050830500.056
purine ribonucleotide catabolic processGO:00091542080.056
regulation of vesicle mediated transportGO:00606271390.056
positive regulation of immune effector processGO:00026991070.056
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.055
regulation of tumor necrosis factor productionGO:0032680490.055
leukocyte proliferationGO:00706611720.055
leukocyte mediated immunityGO:00024431740.055
cellular response to lipidGO:00713961450.053
positive regulation of cytokine productionGO:00018191740.052
immune response regulating cell surface receptor signaling pathwayGO:0002768800.051
olfactory learningGO:000835520.051
cellular response to biotic stimulusGO:0071216920.047
ribonucleotide metabolic processGO:00092592910.047
positive regulation of protein modification processGO:00314012990.047
regulation of cellular ketone metabolic processGO:0010565660.047
reactive oxygen species metabolic processGO:0072593840.046
detection of fungusGO:001604620.046
positive regulation of leukocyte mediated immunityGO:0002705700.045
cellular lipid metabolic processGO:00442553230.045
regulation of mapk cascadeGO:00434082480.045
spermatogenesisGO:00072832840.045
single fertilizationGO:0007338820.044
positive regulation of reactive oxygen species biosynthetic processGO:190342820.044
regulation of reactive oxygen species biosynthetic processGO:190342620.043
cellular amine metabolic processGO:0044106440.042
rho protein signal transductionGO:0007266320.042
apoptotic signaling pathwayGO:00971903060.042
pattern recognition receptor signaling pathwayGO:0002221470.042
positive regulation of defense responseGO:00313491240.040
cellular response to molecule of bacterial originGO:0071219830.040
adaptive immune responseGO:00022501550.040
regulation of reactive oxygen species metabolic processGO:2000377400.040
regulation of transferase activityGO:00513382630.039
cell type specific apoptotic processGO:00972852680.039
cell surface pattern recognition receptor signaling pathwayGO:000275220.039
reactive oxygen species biosynthetic processGO:190340980.039
purine containing compound metabolic processGO:00725213110.039
regulation of natural killer cell mediated cytotoxicityGO:0042269190.039
nucleoside phosphate metabolic processGO:00067533380.039
lymphocyte proliferationGO:00466511640.038
regulation of lymphocyte mediated immunityGO:0002706840.038
leukocyte activation involved in immune responseGO:00023661260.038
male gamete generationGO:00482322850.038
ras protein signal transductionGO:0007265770.037
regulation of secretionGO:00510462740.037
cell activation involved in immune responseGO:00022631260.037
endocytosisGO:00068971680.037
response to molecule of fungal originGO:000223840.036
exocytosisGO:00068871210.035
purine nucleotide metabolic processGO:00061633020.035
interleukin 1 productionGO:0032612310.034
posttranscriptional regulation of gene expressionGO:00106081550.034
chemotaxisGO:00069352470.033
regulation of endocytosisGO:0030100690.033
organic cyclic compound catabolic processGO:19013612950.033
cellular nitrogen compound catabolic processGO:00442702800.032
cellular response to molecule of fungal originGO:007122620.032
germ cell developmentGO:00072811850.032
cellular ketone metabolic processGO:0042180840.031
regulation of lymphocyte proliferationGO:00506701170.031
regulation of cellular component biogenesisGO:00440871810.031
cd4 positive alpha beta t cell cytokine productionGO:003574340.031
regulation of cell cycleGO:00517262810.031
purine ribonucleotide metabolic processGO:00091502900.031
single organism cell adhesionGO:00986021560.030
defense response to virusGO:0051607680.030
regulation of cellular amino acid metabolic processGO:000652150.030
heart contractionGO:0060047930.030
regulation of defense responseGO:00313472330.029
regulation of system processGO:00440572000.029
intrinsic apoptotic signaling pathwayGO:00971931320.029
negative regulation of molecular functionGO:00440922580.029
regulation of multi organism processGO:00439001110.029
negative regulation of phosphate metabolic processGO:00459361840.028
anatomical structure homeostasisGO:00602491450.028
carbohydrate derivative biosynthetic processGO:19011371830.028
amine metabolic processGO:0009308450.028
regulation of blood circulationGO:1903522930.028
generation of precursor metabolites and energyGO:00060911030.027
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.027
actin cytoskeleton organizationGO:00300362200.027
purine ribonucleoside metabolic processGO:00461282410.027
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.027
positive regulation of tumor necrosis factor productionGO:0032760300.027
tumor necrosis factor superfamily cytokine productionGO:0071706510.027
nucleotide catabolic processGO:00091662170.026
activation of innate immune responseGO:0002218560.026
epithelial tube morphogenesisGO:00605623030.026
regulation of response to woundingGO:19030341890.026
regulation of secretion by cellGO:19035302490.026
nucleotide metabolic processGO:00091173320.026
striated muscle tissue developmentGO:00147062930.025
positive regulation of kinase activityGO:00336741550.025
cellular macromolecule catabolic processGO:00442652060.025
positive regulation of protein phosphorylationGO:00019342420.025
cellular chemical homeostasisGO:00550822150.025
regulation of establishment of protein localizationGO:00702011810.025
gland developmentGO:00487323300.024
heterocycle catabolic processGO:00467002800.024
sperm motilityGO:0030317470.024
single organismal cell cell adhesionGO:00163371310.024
t cell mediated immunityGO:0002456500.024
multicellular organismal signalingGO:0035637910.024
cognitionGO:00508901490.024
cellular calcium ion homeostasisGO:00068741190.024
inorganic ion transmembrane transportGO:00986602340.023
response to testosteroneGO:003357430.023
ribonucleoside metabolic processGO:00091192450.023
heart processGO:0003015940.022
regulation of organelle organizationGO:00330432890.022
glycosyl compound metabolic processGO:19016572460.022
aromatic compound catabolic processGO:00194392860.022
regulation of ion homeostasisGO:2000021640.022
interferon gamma productionGO:0032609670.022
membrane organizationGO:00610242450.022
maintenance of locationGO:0051235890.022
purine nucleoside monophosphate metabolic processGO:0009126810.022
regulation of hormone levelsGO:00108172110.022
purine nucleoside metabolic processGO:00422782410.022
cellular homeostasisGO:00197252400.022
adult behaviorGO:00305341350.021
regulation of protein localizationGO:00328802310.021
negative regulation of multi organism processGO:0043901680.021
translationGO:0006412930.021
oocyte constructionGO:000730820.021
spermatid differentiationGO:00485151150.021
positive regulation of t cell activationGO:00508701010.021
positive regulation of apoptotic processGO:00430652170.021
negative regulation of defense responseGO:0031348770.020
humoral immune responseGO:0006959570.020
cytokine mediated signaling pathwayGO:00192211150.020
purine ribonucleoside catabolic processGO:00461302050.020
monocarboxylic acid metabolic processGO:00327871910.020
regulation of protein kinase activityGO:00458592320.020
response to organonitrogen compoundGO:00102432460.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
purine nucleoside triphosphate metabolic processGO:00091442260.020
t cell extravasationGO:007268340.020
cation transmembrane transportGO:00986552660.019
nucleobase containing small molecule metabolic processGO:00550863520.019
sensory perceptionGO:00076002450.019
b cell activationGO:00421131610.019
cellular response to cytokine stimulusGO:00713451890.019
purine nucleoside triphosphate catabolic processGO:00091462030.019
telencephalon developmentGO:00215371860.019
negative regulation of cell proliferationGO:00082852960.019
mitotic cell cycleGO:00002781950.019
sequestering of calcium ionGO:0051208180.019
rac protein signal transductionGO:0016601130.018
nucleoside triphosphate metabolic processGO:00091412300.018
ossificationGO:00015032160.018
ribonucleoside monophosphate metabolic processGO:0009161800.018
receptor mediated endocytosisGO:0006898510.018
hematopoietic progenitor cell differentiationGO:00022441430.018
response to stilbenoidGO:0035634220.018
calcium ion homeostasisGO:00550741270.018
membrane depolarizationGO:0051899640.018
regulation of cell migrationGO:00303342190.018
nucleoside phosphate catabolic processGO:19012922220.017
organophosphate catabolic processGO:00464342320.017
nucleoside monophosphate metabolic processGO:0009123850.017
cell maturationGO:00484691270.017
positive regulation of transferase activityGO:00513471670.017
locomotory behaviorGO:00076261950.017
negative regulation of intracellular signal transductionGO:19025321670.017
metal ion homeostasisGO:00550651890.017
regulation of hormone secretionGO:0046883880.017
positive regulation of cellular amine metabolic processGO:003324050.017
purine ribonucleoside monophosphate metabolic processGO:0009167800.017
phagocytosisGO:0006909660.017
ribose phosphate metabolic processGO:00196932910.017
learning or memoryGO:00076111480.017
purine nucleoside catabolic processGO:00061522050.017
intrinsic apoptotic signaling pathway in response to osmotic stressGO:000862720.017
meiotic cell cycleGO:00513211220.017
oocyte axis specificationGO:000730920.017
cellular carbohydrate metabolic processGO:00442621190.016
carboxylic acid biosynthetic processGO:0046394860.016
atp catabolic processGO:0006200550.016
defense response to other organismGO:00985421970.016
nitric oxide metabolic processGO:0046209250.016
spermatid developmentGO:00072861080.016
t cell activationGO:00421102890.016
myeloid leukocyte differentiationGO:00025731190.016
organelle fissionGO:00482851700.016
circulatory system processGO:00030131970.016
negative regulation of leukocyte mediated immunityGO:0002704290.016
nucleocytoplasmic transportGO:00069131390.016
innate immune response in mucosaGO:000222730.016
fatty acid metabolic processGO:00066311210.016
purine containing compound catabolic processGO:00725232130.016
positive regulation of programmed cell deathGO:00430682180.016
cell chemotaxisGO:0060326810.016
regulation of synaptic growth at neuromuscular junctionGO:000858240.016
granzyme mediated apoptotic signaling pathwayGO:000862610.015
nitric oxide biosynthetic processGO:0006809250.015
negative regulation of cellular component organizationGO:00511291940.015
g protein coupled receptor signaling pathwayGO:00071862430.015
leukocyte differentiationGO:00025213420.015
cation transportGO:00068123990.015
homeostasis of number of cellsGO:00488722100.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.015
positive regulation of cell deathGO:00109422240.015
regulation of monocyte chemotaxisGO:009002530.015
positive regulation of cell activationGO:00508671580.015
organophosphate biosynthetic processGO:00904071220.015
branching morphogenesis of an epithelial tubeGO:00487541590.015
skeletal muscle organ developmentGO:00605381630.015
meiotic nuclear divisionGO:00071261150.015
macromolecule catabolic processGO:00090572810.015
response to oxidative stressGO:00069791230.015
negative regulation of cellular protein metabolic processGO:00322692470.015
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117940.015
regulation of interferon gamma productionGO:0032649570.015
inflammatory responseGO:00069542440.015
regulation of t cell activationGO:00508631700.015
positive regulation of cell projection organizationGO:0031346950.015
mitotic cell cycle processGO:19030471590.015
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.014
energy derivation by oxidation of organic compoundsGO:0015980770.014
blood vessel morphogenesisGO:00485142850.014
positive regulation of secretionGO:00510471300.014
regulation of leukocyte proliferationGO:00706631210.014
positive regulation of monocyte chemotaxisGO:009002620.014
response to organic cyclic compoundGO:00140701980.014
negative regulation of cell activationGO:00508661110.014
regulation of striated muscle cell differentiationGO:0051153810.014
detection of other organismGO:009854380.014
positive regulation of t cell receptor signaling pathwayGO:005086240.014
interleukin 8 productionGO:003263740.014
inorganic cation transmembrane transportGO:00986622070.014
fertilizationGO:00095661270.014
ribonucleoside catabolic processGO:00424542060.014
regulation of cellular catabolic processGO:00313292420.014
ion transmembrane transportGO:00342203610.014
energy reserve metabolic processGO:0006112390.014
organelle assemblyGO:00709251770.014
leukocyte chemotaxisGO:0030595690.014
regulation of actin cytoskeleton organizationGO:0032956840.014
ribonucleoside monophosphate catabolic processGO:0009158570.014
cytoplasmic transportGO:00164822340.014
organ regenerationGO:003110020.013
regulation of phagocytosisGO:0050764330.013
cellular divalent inorganic cation homeostasisGO:00725031270.013
second messenger mediated signalingGO:0019932730.013
atp metabolic processGO:0046034750.013
positive regulation of renal sodium excretionGO:003581520.013
skeletal system developmentGO:00015013560.013
regulation of b cell activationGO:0050864810.013
carbohydrate metabolic processGO:00059752300.013
purine ribonucleoside triphosphate metabolic processGO:00092052200.013
female gamete generationGO:0007292740.013
regulation of t cell proliferationGO:0042129920.013
cellular ion homeostasisGO:00068731650.013
protein catabolic processGO:00301632210.013
transmembrane transportGO:00550854120.013
positive regulation of nervous system developmentGO:00519622210.013
learningGO:0007612980.013
carbohydrate derivative catabolic processGO:19011362310.013
cellular response to organonitrogen compoundGO:00714171450.013
peptidyl tyrosine phosphorylationGO:00181081430.013
mapk cascadeGO:00001652810.013
lymphocyte activation involved in immune responseGO:0002285930.013
morphogenesis of a branching structureGO:00017632030.013
interspecies interaction between organismsGO:0044419830.012
nuclear divisionGO:00002801580.012
regulation of hydrolase activityGO:00513362460.012
lipid biosynthetic processGO:00086101790.012
nucleoside metabolic processGO:00091162460.012
dna metabolic processGO:00062593030.012
regulation of interleukin 8 productionGO:003267730.012
regulation of protein transportGO:00512231630.012
positive regulation of immunological synapse formationGO:200052210.012
regulation of monocyte extravasationGO:200043720.012
cytokine secretionGO:0050663720.012
hematopoietic stem cell migrationGO:003570110.012
negative regulation of homeostatic processGO:0032845710.012
regulation of cytokine secretionGO:0050707610.012
granulocyte chemotaxisGO:0071621390.012
positive regulation of apoptotic signaling pathwayGO:2001235950.012
purine nucleoside monophosphate catabolic processGO:0009128580.012
respiratory system developmentGO:00605411900.012
ribonucleoside triphosphate catabolic processGO:00092031990.012
leukocyte migrationGO:00509001240.012
neuromuscular processGO:0050905990.012
nucleoside monophosphate catabolic processGO:0009125590.012
negative regulation of transferase activityGO:0051348850.012
ubiquitin dependent protein catabolic processGO:00065111290.012
organ or tissue specific immune responseGO:0002251130.012
response to peptide hormoneGO:00434341270.012
innate immune response activating signal transductionGO:0002758500.012
negative regulation of phosphorylationGO:00423261660.012
cell cell recognitionGO:0009988440.012
negative regulation of macrophage apoptotic processGO:200011030.012
regulation of protein stabilityGO:0031647520.012
modification dependent protein catabolic processGO:00199411330.012
action potentialGO:0001508780.012
positive regulation of interferon gamma productionGO:0032729390.012
positive regulation of lymphocyte activationGO:00512511400.012
negative regulation of cellular amine metabolic processGO:003323910.012
peptide hormone secretionGO:00300721090.012
regulation of postsynaptic membrane potentialGO:0060078480.012
calcium ion transport into cytosolGO:0060402480.012
myotube differentiationGO:00149021050.012
regulation of protein serine threonine kinase activityGO:00719001570.012
mitochondrion organizationGO:00070051340.012
dendritic spine organizationGO:0097061260.012
regulation of rho protein signal transductionGO:0035023710.012
small molecule biosynthetic processGO:00442831320.012
endomembrane system organizationGO:00102561470.012
ear developmentGO:00435832000.012
regulation of cytoplasmic transportGO:19036491120.012
fatty acid biosynthetic processGO:0006633410.012
negative regulation of secretion by cellGO:1903531540.011
negative regulation of eosinophil degranulationGO:004331010.011
protein maturationGO:00516041760.011
tumor necrosis factor productionGO:0032640500.011
morphogenesis of a branching epitheliumGO:00611381930.011
positive regulation of lymphocyte proliferationGO:0050671700.011
regulation of cellular amine metabolic processGO:0033238200.011
eosinophil activation involved in immune responseGO:000227810.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.011
oxidation reduction processGO:00551143420.011
hormone secretionGO:00468791280.011
regulation of purine nucleotide metabolic processGO:19005421690.011
interleukin 1 beta productionGO:0032611300.011
response to insulinGO:00328681000.011
proteolysis involved in cellular protein catabolic processGO:00516031470.011
cellular protein catabolic processGO:00442571550.011
purine ribonucleoside monophosphate catabolic processGO:0009169570.011
regulation of map kinase activityGO:00434051200.011
lung developmentGO:00303241640.011
oocyte developmentGO:0048599330.011
blood circulationGO:00080151950.011
b cell differentiationGO:0030183780.011
eosinophil activationGO:004330710.011
defense response to bacteriumGO:00427421190.011
positive regulation of growthGO:00459271040.011
regulation of cell cycle processGO:00105641600.011
regulation of apoptotic signaling pathwayGO:20012331970.011
angiogenesisGO:00015252010.011
regulation of kinase activityGO:00435492490.011
cellular respirationGO:0045333380.010
oocyte anterior posterior axis specificationGO:000731420.010
divalent metal ion transportGO:00708381720.010
cellular metal ion homeostasisGO:00068751510.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
pigmentationGO:0043473710.010
positive regulation of endocytosisGO:0045807420.010
regulation of mitotic cell cycleGO:00073461260.010
glycosyl compound catabolic processGO:19016582060.010
interleukin 12 secretionGO:007261030.010
positive regulation of necrotic cell deathGO:001094010.010
rna interferenceGO:001624620.010
regulation of homeostatic processGO:00328441820.010
leukocyte apoptotic processGO:0071887710.010
protein autophosphorylationGO:0046777610.010
muscle cell differentiationGO:00426922610.010
regulation of neuron apoptotic processGO:00435231220.010
rna processingGO:00063961050.010
microglia differentiationGO:001400420.010
regulation of ras protein signal transductionGO:00465781140.010
negative regulation of lymphocyte mediated immunityGO:0002707210.010

Klra8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.041
cancerDOID:16200.031
disease of cellular proliferationDOID:1456600.031
organ system cancerDOID:005068600.018
connective tissue diseaseDOID:6500.016
musculoskeletal system diseaseDOID:1700.016
disease of anatomical entityDOID:700.016
rheumatoid arthritisDOID:714800.016
bone inflammation diseaseDOID:334200.016
bone diseaseDOID:008000100.016
arthritisDOID:84800.016
inherited metabolic disorderDOID:65500.012
immune system diseaseDOID:291400.012