Mus musculus

0 known processes

Polr1a

polymerase (RNA) I polypeptide A

(Aliases: mRPA1,RPA194,3010014K16Rik,194kDa,Rpo1-4)

Polr1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062593030.291
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.139
regulation of cell cycle processGO:00105641600.114
cellular amino acid metabolic processGO:00065201030.077
histone methylationGO:0016571710.073
histone modificationGO:00165701590.065
peptidyl amino acid modificationGO:00181933360.063
germ cell developmentGO:00072811850.062
positive regulation of cell deathGO:00109422240.058
chromatin organizationGO:00063252060.058
leukocyte differentiationGO:00025213420.058
negative regulation of cell cycleGO:00457861230.058
regulation of organelle organizationGO:00330432890.056
protein methylationGO:0006479810.056
endonucleolytic cleavage involved in rrna processingGO:000047810.055
cellular ketone metabolic processGO:0042180840.054
positive regulation of programmed cell deathGO:00430682180.053
negative regulation of protein metabolic processGO:00512482820.052
methylationGO:00322591340.051
macromolecule methylationGO:00434141200.049
dna repairGO:00062811070.049
blastocyst growthGO:0001832230.048
positive regulation of apoptotic processGO:00430652170.048
covalent chromatin modificationGO:00165691630.048
dna methylation involved in gamete generationGO:0043046150.047
rna processingGO:00063961050.047
nuclear divisionGO:00002801580.047
cellular response to dna damage stimulusGO:00069742070.043
action potentialGO:0001508780.042
nuclear transportGO:00511691390.042
regulation of cell cycleGO:00517262810.042
regulation of cellular catabolic processGO:00313292420.042
blastocyst developmentGO:0001824800.041
male gamete generationGO:00482322850.038
maturation of 5 8s rrnaGO:000046010.037
regulation of cellular ketone metabolic processGO:0010565660.037
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.036
positive regulation of hydrolase activityGO:00513451480.035
stem cell differentiationGO:00488632680.034
immune effector processGO:00022523210.034
cellular amine metabolic processGO:0044106440.032
transcription from rna polymerase i promoterGO:0006360130.032
histone h3 acetylationGO:0043966140.032
cell type specific apoptotic processGO:00972852680.032
transmission of nerve impulseGO:0019226760.032
lymphocyte differentiationGO:00300982420.032
negative regulation of protein modification processGO:00314001630.032
regulation of mitotic cell cycle phase transitionGO:1901990730.031
stem cell maintenanceGO:00198271300.031
regulation of chromosome organizationGO:0033044830.031
regulation of neuron deathGO:19012141340.030
gonad developmentGO:00084061410.030
mapk cascadeGO:00001652810.030
astrocyte differentiationGO:0048708430.030
protein alkylationGO:0008213810.030
g1 s transition of mitotic cell cycleGO:0000082570.029
negative regulation of cellular protein metabolic processGO:00322692470.029
regulation of cellular amine metabolic processGO:0033238200.029
intrinsic apoptotic signaling pathwayGO:00971931320.029
apoptotic signaling pathwayGO:00971903060.028
regulation of cellular amino acid metabolic processGO:000652150.028
amine metabolic processGO:0009308450.027
neuroblast differentiationGO:001401620.027
spermatogenesisGO:00072832840.026
negative regulation of neuron apoptotic processGO:0043524920.026
engulfment of apoptotic cellGO:004365230.026
negative regulation of cell divisionGO:0051782240.026
macromolecule catabolic processGO:00090572810.026
cell divisionGO:00513011200.026
positive regulation of transcription from rna polymerase i promoterGO:004594330.026
gland developmentGO:00487323300.026
digestive tract developmentGO:00485651900.025
protein dna complex subunit organizationGO:0071824280.025
heterocycle catabolic processGO:00467002800.025
sensory system developmentGO:004888030.025
small molecule biosynthetic processGO:00442831320.025
cleavage involved in rrna processingGO:000046910.025
mitotic cell cycle processGO:19030471590.025
nitrogen compound transportGO:00717052710.024
oxidation reduction processGO:00551143420.024
ribonucleoside metabolic processGO:00091192450.024
development of primary sexual characteristicsGO:00451371430.024
chromatin modificationGO:00165681870.024
dna packagingGO:0006323300.024
b cell mediated immunityGO:0019724710.024
immunoglobulin productionGO:0002377730.024
negative regulation of cell developmentGO:00107211690.023
response to oxidative stressGO:00069791230.023
myelinationGO:0042552740.023
protein maturationGO:00516041760.023
neuron deathGO:00709971540.023
negative regulation of cell cycle processGO:0010948690.023
regulation of neuron differentiationGO:00456642810.022
regulation of neuron apoptotic processGO:00435231220.022
female gamete generationGO:0007292740.022
negative regulation of protein processingGO:0010955790.022
regulation of proteolysisGO:00301621640.022
posttranscriptional regulation of gene expressionGO:00106081550.022
neuron apoptotic processGO:00514021420.022
negative regulation of nervous system developmentGO:00519611560.022
negative regulation of neuron deathGO:1901215980.022
trophectodermal cell differentiationGO:0001829210.022
regulation of membrane potentialGO:00423911920.021
regulation of asymmetric cell divisionGO:000978640.021
purine ribonucleoside triphosphate catabolic processGO:00092071990.021
regulation of establishment of protein localizationGO:00702011810.021
regulation of histone modificationGO:0031056560.021
negative regulation of cellular component organizationGO:00511291940.021
muscle tissue developmentGO:00605373080.021
purine nucleoside triphosphate metabolic processGO:00091442260.021
ossificationGO:00015032160.021
neurohypophysis developmentGO:002198520.021
rna splicingGO:0008380540.021
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.021
embryonic organ morphogenesisGO:00485622760.021
regulation of cell divisionGO:0051302760.020
meiotic nuclear divisionGO:00071261150.020
protein acylationGO:0043543640.020
regulation of cysteine type endopeptidase activityGO:2000116650.020
positive regulation of growthGO:00459271040.020
protein processingGO:00164851630.020
cytoplasmic transportGO:00164822340.020
regulation of cell cycle phase transitionGO:1901987770.020
glycosyl compound metabolic processGO:19016572460.020
multicellular organismal signalingGO:0035637910.019
transmembrane transportGO:00550854120.019
positive regulation of cell cycle processGO:0090068610.019
chromatin silencing at rdnaGO:000018330.019
negative regulation of organelle organizationGO:0010639900.019
intracellular protein transportGO:00068862040.019
leukocyte mediated immunityGO:00024431740.019
cellular carbohydrate metabolic processGO:00442621190.019
neuronal action potentialGO:0019228540.019
ncrna processingGO:0034470260.019
purine nucleoside metabolic processGO:00422782410.019
gliogenesisGO:00420631410.019
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.018
organelle fissionGO:00482851700.018
reactive oxygen species metabolic processGO:0072593840.018
forebrain developmentGO:00309003020.018
chromatin mediated maintenance of transcriptionGO:004809620.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
organelle localizationGO:00516401790.018
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.018
cellular homeostasisGO:00197252400.018
nucleoside catabolic processGO:00091642060.018
regulation of hydrolase activityGO:00513362460.018
striated muscle tissue developmentGO:00147062930.018
signal transduction involved in dna damage checkpointGO:007242230.018
purine containing compound catabolic processGO:00725232130.018
atp metabolic processGO:0046034750.018
purine nucleotide metabolic processGO:00061633020.017
histone h4 k16 acetylationGO:004398430.017
nucleotide catabolic processGO:00091662170.017
adaptive immune responseGO:00022501550.017
negative regulation of mitotic cell cycleGO:0045930580.017
mrna transcriptionGO:000929940.017
digestive system developmentGO:00551232000.017
b cell activationGO:00421131610.017
glial cell differentiationGO:00100011310.017
nucleobase containing small molecule metabolic processGO:00550863520.017
positive regulation of nervous system developmentGO:00519622210.017
proteolysis involved in cellular protein catabolic processGO:00516031470.016
positive regulation of cellular amine metabolic processGO:003324050.016
peptidyl arginine omega n methylationGO:003524720.016
protein import into nucleusGO:0006606950.016
sensory perceptionGO:00076002450.016
purine ribonucleoside triphosphate metabolic processGO:00092052200.016
protein modification by small protein conjugation or removalGO:00706472070.016
skeletal system developmentGO:00015013560.016
double strand break repairGO:0006302480.016
sensory organ morphogenesisGO:00905962420.016
aromatic compound catabolic processGO:00194392860.016
wound healingGO:00420601570.016
lymphocyte mediated immunityGO:00024491390.016
cellular respirationGO:0045333380.016
epithalamus developmentGO:002153820.015
maintenance of locationGO:0051235890.015
establishment of protein localization to organelleGO:00725941180.015
respiratory system developmentGO:00605411900.015
peptidyl lysine modificationGO:0018205770.015
purine ribonucleoside metabolic processGO:00461282410.015
meiotic cell cycleGO:00513211220.015
cellular protein catabolic processGO:00442571550.015
endocytosisGO:00068971680.015
spermatid differentiationGO:00485151150.015
mesoderm developmentGO:00074981000.015
mitotic cell cycle checkpointGO:0007093310.015
compound eye developmentGO:004874910.015
nucleoside metabolic processGO:00091162460.015
regulation of mapk cascadeGO:00434082480.015
ribonucleotide metabolic processGO:00092592910.015
sensory perception of mechanical stimulusGO:00509541070.015
central nervous system neuron differentiationGO:00219531620.015
nucleocytoplasmic transportGO:00069131390.015
ribose phosphate metabolic processGO:00196932910.015
cellular macromolecule catabolic processGO:00442652060.015
carbohydrate metabolic processGO:00059752300.015
regulation of nuclear divisionGO:0051783560.015
tissue homeostasisGO:00018941150.015
somatic cell dna recombinationGO:0016444510.015
meiosis iGO:0007127600.015
developmental maturationGO:00217001930.015
dct cell differentiationGO:007206930.014
regulation of kinase activityGO:00435492490.014
regulation of cytoplasmic transportGO:19036491120.014
regulation of mrna metabolic processGO:1903311430.014
internal protein amino acid acetylationGO:0006475420.014
axon ensheathmentGO:0008366760.014
purine containing compound metabolic processGO:00725213110.014
anatomical structure homeostasisGO:00602491450.014
mitotic cell cycleGO:00002781950.014
heart morphogenesisGO:00030071780.014
single organism cell adhesionGO:00986021560.014
regulation of reactive oxygen species metabolic processGO:2000377400.014
positive regulation of keratinocyte proliferationGO:001083840.014
cation transportGO:00068123990.014
vitamin transmembrane transportGO:003546140.014
ribonucleoside triphosphate metabolic processGO:00091992200.014
somatotropin secreting cell differentiationGO:006012640.014
regulation of homeostatic processGO:00328441820.014
positive regulation of inositol phosphate biosynthetic processGO:006073220.014
neuromuscular processGO:0050905990.014
cellular chemical homeostasisGO:00550822150.014
negative regulation of dna replicationGO:000815640.014
nucleoside triphosphate metabolic processGO:00091412300.014
negative regulation of nuclear divisionGO:0051784190.013
nucleic acid phosphodiester bond hydrolysisGO:0090305490.013
locomotory behaviorGO:00076261950.013
urogenital system developmentGO:00016552610.013
nucleotide metabolic processGO:00091173320.013
multicellular organismal homeostasisGO:00488711640.013
ribonucleoside monophosphate metabolic processGO:0009161800.013
exocytosisGO:00068871210.013
regulation of synaptic growth at neuromuscular junctionGO:000858240.013
positive regulation of peptidase activityGO:0010952490.013
chromosome segregationGO:0007059480.013
regulation of protein maturationGO:1903317960.013
protein targetingGO:00066051430.013
regulation of apoptotic signaling pathwayGO:20012331970.013
regulation of wnt signaling pathwayGO:00301111230.013
regulation of cell cycle arrestGO:0071156120.013
chromatin assemblyGO:0031497130.013
organic cyclic compound catabolic processGO:19013612950.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.013
cellular response to lipidGO:00713961450.013
cell cycle arrestGO:0007050370.013
cell growthGO:00160491300.013
signal transduction involved in mitotic dna damage checkpointGO:190240230.013
regulation of protein kinase activityGO:00458592320.013
response to light stimulusGO:00094161350.013
immunoglobulin mediated immune responseGO:0016064690.013
positive regulation of cell cycleGO:0045787920.013
negative regulation of proteolysisGO:0045861740.013
nuclear importGO:0051170950.012
genetic imprintingGO:0071514270.012
oocyte anterior posterior axis specificationGO:000731420.012
purine ribonucleotide metabolic processGO:00091502900.012
regulation of mitotic cell cycleGO:00073461260.012
modification dependent protein catabolic processGO:00199411330.012
rap protein signal transductionGO:003248630.012
extracellular structure organizationGO:00430621480.012
digestive tract morphogenesisGO:00485461470.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.012
regulation of transferase activityGO:00513382630.012
regulation of cellular protein catabolic processGO:1903362610.012
organophosphate catabolic processGO:00464342320.012
histone acetylationGO:0016573410.012
positive regulation of cysteine type endopeptidase activityGO:2001056390.012
purine nucleoside catabolic processGO:00061522050.012
protein localization to organelleGO:00333651850.012
organonitrogen compound biosynthetic processGO:19015661920.012
regulation of cellular response to stressGO:00801351590.012
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.012
protein localization to nucleusGO:00345041210.012
response to organic cyclic compoundGO:00140701980.012
stem cell developmentGO:00488642190.012
mesoderm formationGO:0001707620.012
embryonic skeletal system developmentGO:00487061200.012
dna damage checkpointGO:0000077260.012
t cell differentiationGO:00302171740.012
lipid biosynthetic processGO:00086101790.012
negative regulation of cellular catabolic processGO:0031330470.012
spermatid developmentGO:00072861080.012
wnt signaling pathwayGO:00160551880.012
chromosome separationGO:0051304140.012
cation homeostasisGO:00550802120.012
sensory perception of soundGO:0007605970.012
regulation of inositol phosphate biosynthetic processGO:001091930.012
purine ribonucleoside monophosphate metabolic processGO:0009167800.012
organonitrogen compound catabolic processGO:19015652640.011
regulation of secretion by cellGO:19035302490.011
somatic diversification of immune receptorsGO:0002200530.011
hindbrain developmentGO:00309021280.011
positive regulation of endopeptidase activityGO:0010950430.011
regulation of inositol trisphosphate biosynthetic processGO:003296030.011
mrna metabolic processGO:0016071840.011
alcohol metabolic processGO:00060661160.011
cellular nitrogen compound catabolic processGO:00442702800.011
organic hydroxy compound biosynthetic processGO:1901617770.011
transdifferentiationGO:006029010.011
embryonic skeletal system morphogenesisGO:0048704910.011
calcium ion transportGO:00068161590.011
blastocyst formationGO:0001825330.011
dna conformation changeGO:0071103370.011
nucleoside phosphate metabolic processGO:00067533380.011
regulation of protein processingGO:0070613960.011
single organism nuclear importGO:1902593950.011
habenula developmentGO:002198620.011
protein catabolic processGO:00301632210.011
protein importGO:00170381010.011
regulation of cell projection organizationGO:00313442060.011
maturation of ssu rrnaGO:003049010.011
regulation of defense responseGO:00313472330.011
divalent metal ion transportGO:00708381720.011
internal peptidyl lysine acetylationGO:0018393420.011
renal system developmentGO:00720012250.010
oocyte axis specificationGO:000730920.010
rna phosphodiester bond hydrolysis endonucleolyticGO:0090502100.010
regulation of protein targetingGO:1903533610.010
nucleus organizationGO:0006997450.010
tube formationGO:00351481400.010
response to organonitrogen compoundGO:00102432460.010
regulation of ossificationGO:00302781120.010
multi organism behaviorGO:0051705620.010
regulation of cell cycle checkpointGO:190197690.010
organic hydroxy compound metabolic processGO:19016152030.010
dna recombinationGO:0006310920.010
regionalizationGO:00030023370.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.010
negative regulation of cell cycle phase transitionGO:1901988480.010
regulation of response to woundingGO:19030341890.010
mitochondrial dna metabolic processGO:0032042130.010
cell differentiation involved in metanephros developmentGO:0072202120.010
negative regulation of cell proliferationGO:00082852960.010
mrna processingGO:0006397630.010
b cell differentiationGO:0030183780.010
response to uvGO:0009411440.010
ribonucleotide catabolic processGO:00092612080.010

Polr1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.031
disease of anatomical entityDOID:700.031
eye and adnexa diseaseDOID:149200.016
eye diseaseDOID:561400.016
sensory system diseaseDOID:005015500.016
disease of cellular proliferationDOID:1456600.015
retinal diseaseDOID:567900.014
retinal degenerationDOID:846600.014
organ system cancerDOID:005068600.014
cancerDOID:16200.014
central nervous system diseaseDOID:33100.012
neurodegenerative diseaseDOID:128900.011
disease of mental healthDOID:15000.011