Mus musculus

53 known processes

Polr1b

polymerase (RNA) I polypeptide B

(Aliases: Rpo1-2,RPA116,RPA2,RPA135,128kDa,D630020H17Rik)

Polr1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
endonucleolytic cleavage involved in rrna processingGO:000047810.264
transcription from rna polymerase i promoterGO:0006360130.212
ribosomal small subunit biogenesisGO:004227440.172
transcription initiation from rna polymerase i promoterGO:000636140.131
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000047910.108
rna processingGO:00063961050.098
cellular amino acid metabolic processGO:00065201030.081
cleavage involved in rrna processingGO:000046910.056
transmembrane transportGO:00550854120.047
apoptotic signaling pathwayGO:00971903060.047
nuclear divisionGO:00002801580.044
maturation of 5 8s rrnaGO:000046010.041
histone methylationGO:0016571710.041
intrinsic apoptotic signaling pathwayGO:00971931320.038
organonitrogen compound biosynthetic processGO:19015661920.037
organelle fissionGO:00482851700.032
ion transmembrane transportGO:00342203610.031
circadian regulation of gene expressionGO:0032922480.031
cellular amine metabolic processGO:0044106440.031
dna metabolic processGO:00062593030.029
oocyte anterior posterior axis specificationGO:000731420.029
oxidation reduction processGO:00551143420.029
blastocyst developmentGO:0001824800.028
meiotic nuclear divisionGO:00071261150.028
macromolecule methylationGO:00434141200.028
homeostasis of number of cellsGO:00488722100.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
regulation of anatomical structure sizeGO:00900661780.026
cellular ketone metabolic processGO:0042180840.025
response to radiationGO:00093141650.025
response to light stimulusGO:00094161350.025
regulation of intracellular transportGO:00323861590.025
microtubule cytoskeleton organizationGO:00002261570.024
muscle tissue developmentGO:00605373080.024
regulation of cellular component sizeGO:00325351210.023
regulation of organelle organizationGO:00330432890.023
cellular amino acid biosynthetic processGO:0008652220.023
rna phosphodiester bond hydrolysis endonucleolyticGO:0090502100.022
cajal body organizationGO:003057610.022
cation homeostasisGO:00550802120.022
respiratory system developmentGO:00605411900.022
nucleoside phosphate catabolic processGO:19012922220.022
alpha amino acid biosynthetic processGO:1901607150.022
ossificationGO:00015032160.022
dna endoreduplicationGO:004202340.022
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.022
mitochondrion organizationGO:00070051340.022
nucleobase containing small molecule metabolic processGO:00550863520.021
methylationGO:00322591340.021
ribosome biogenesisGO:0042254200.021
negative regulation of cell cycleGO:00457861230.020
endocytosisGO:00068971680.020
Worm
positive regulation of programmed cell deathGO:00430682180.020
small gtpase mediated signal transductionGO:0007264970.020
cation transportGO:00068123990.020
dna templated transcriptional preinitiation complex assemblyGO:007089740.020
purine containing compound metabolic processGO:00725213110.020
rna 5 end processingGO:000096610.020
leukocyte differentiationGO:00025213420.020
lung developmentGO:00303241640.020
meiotic cell cycleGO:00513211220.020
amine metabolic processGO:0009308450.020
peptidyl amino acid modificationGO:00181933360.019
regulation of cell sizeGO:0008361720.019
anion transportGO:00068201770.018
response to organic cyclic compoundGO:00140701980.018
cellular homeostasisGO:00197252400.018
action potentialGO:0001508780.018
regulation of cellular amine metabolic processGO:0033238200.018
regulation of cell cycle processGO:00105641600.018
ribose phosphate metabolic processGO:00196932910.018
cellular response to lipidGO:00713961450.018
lateral inhibitionGO:004633110.018
alpha amino acid metabolic processGO:1901605590.018
regulation of protein complex assemblyGO:0043254830.018
organic anion transportGO:00157111370.018
carbohydrate metabolic processGO:00059752300.017
regulation of membrane potentialGO:00423911920.017
cellular chemical homeostasisGO:00550822150.017
ribonucleoside metabolic processGO:00091192450.017
regulation of cytoskeleton organizationGO:00514931220.017
digestive system developmentGO:00551232000.017
meiotic cell cycle processGO:1903046770.017
regulation of cellular amino acid metabolic processGO:000652150.017
cellular response to peptide hormone stimulusGO:0071375920.017
maternal determination of anterior posterior axis embryoGO:000835820.017
ribonucleotide metabolic processGO:00092592910.017
developmental maturationGO:00217001930.017
sensory perceptionGO:00076002450.017
mrna metabolic processGO:0016071840.017
regulation of cell cycleGO:00517262810.016
innate immune responseGO:00450871570.016
cellular ion homeostasisGO:00068731650.016
folic acid containing compound metabolic processGO:000676030.016
immune effector processGO:00022523210.016
oocyte constructionGO:000730820.016
purine ribonucleotide metabolic processGO:00091502900.016
positive regulation of cellular amine metabolic processGO:003324050.015
digestive tract developmentGO:00485651900.015
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.015
spinal cord developmentGO:0021510810.015
anion transmembrane transportGO:0098656710.015
myeloid cell differentiationGO:00300992330.015
energy derivation by oxidation of organic compoundsGO:0015980770.015
b cell activationGO:00421131610.015
membrane organizationGO:00610242450.015
Worm
multicellular organismal signalingGO:0035637910.015
signal transduction by p53 class mediatorGO:0072331510.015
purine nucleoside metabolic processGO:00422782410.015
peptidyl arginine omega n methylationGO:003524720.015
regulation of hydrolase activityGO:00513362460.015
oocyte axis specificationGO:000730920.015
cell divisionGO:00513011200.014
cell cycle switchingGO:006018410.014
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.014
negative regulation of cellular component organizationGO:00511291940.014
mitotic cell cycleGO:00002781950.014
positive regulation of apoptotic processGO:00430652170.014
amino acid transportGO:0006865610.014
purine ribonucleotide catabolic processGO:00091542080.014
purine nucleoside triphosphate metabolic processGO:00091442260.014
establishment of protein localization to organelleGO:00725941180.014
positive regulation of cell deathGO:00109422240.014
single organism cell adhesionGO:00986021560.014
regulation of homeostatic processGO:00328441820.014
protein maturationGO:00516041760.014
cellular response to dna damage stimulusGO:00069742070.014
signal transduction involved in mitotic dna damage checkpointGO:190240230.014
establishment or maintenance of cytoskeleton polarityGO:003095220.014
l serine metabolic processGO:000656320.014
organelle localizationGO:00516401790.014
segmentationGO:0035282930.014
nucleoside phosphate metabolic processGO:00067533380.014
carboxylic acid transportGO:00469421000.014
neuronal action potentialGO:0019228540.014
skeletal system developmentGO:00015013560.013
regulation of actin filament based processGO:0032970990.013
cellularizationGO:000734910.013
regulation of apoptotic signaling pathwayGO:20012331970.013
transmission of nerve impulseGO:0019226760.013
regulation of nucleocytoplasmic transportGO:0046822730.013
organic acid biosynthetic processGO:0016053860.013
nucleoside triphosphate catabolic processGO:00091432050.013
carbohydrate derivative biosynthetic processGO:19011371830.013
production of molecular mediator of immune responseGO:00024401030.013
inorganic ion transmembrane transportGO:00986602340.013
purine ribonucleoside metabolic processGO:00461282410.013
nucleoside catabolic processGO:00091642060.013
cellular nitrogen compound catabolic processGO:00442702800.013
organonitrogen compound catabolic processGO:19015652640.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.013
regulation of protein localizationGO:00328802310.013
striated muscle tissue developmentGO:00147062930.013
circadian rhythmGO:00076231140.012
purine nucleotide metabolic processGO:00061633020.012
leukocyte activation involved in immune responseGO:00023661260.012
rna splicingGO:0008380540.012
cellular response to abiotic stimulusGO:0071214560.012
cellular response to hormone stimulusGO:00328701500.012
nucleus organizationGO:0006997450.012
lymphocyte mediated immunityGO:00024491390.012
neuron apoptotic processGO:00514021420.012
nucleotide catabolic processGO:00091662170.012
ribonucleoprotein complex subunit organizationGO:0071826280.012
intracellular protein transportGO:00068862040.012
regulation of cellular ketone metabolic processGO:0010565660.012
metal ion homeostasisGO:00550651890.012
lymphocyte differentiationGO:00300982420.012
negative regulation of cell sizeGO:004579230.012
cytokine productionGO:00018163190.012
carboxylic acid biosynthetic processGO:0046394860.012
purine nucleotide catabolic processGO:00061952110.012
purine nucleoside triphosphate catabolic processGO:00091462030.012
negative regulation of neuron deathGO:1901215980.011
positive regulation of cell cycleGO:0045787920.011
respiratory tube developmentGO:00303231670.011
regulation of cytokine productionGO:00018172660.011
glycosyl compound metabolic processGO:19016572460.011
rhythmic processGO:00485111740.011
regulation of wnt signaling pathwayGO:00301111230.011
cellular response to organic cyclic compoundGO:0071407870.011
protein targetingGO:00066051430.011
ribonucleoside triphosphate metabolic processGO:00091992200.011
purine containing compound catabolic processGO:00725232130.011
l amino acid transportGO:0015807320.011
regulation of nucleoside metabolic processGO:00091181300.011
purine ribonucleoside catabolic processGO:00461302050.011
protein catabolic processGO:00301632210.011
cell maturationGO:00484691270.011
canonical wnt signaling pathwayGO:00600701300.011
inorganic cation transmembrane transportGO:00986622070.011
purine nucleoside catabolic processGO:00061522050.011
regulation of proteolysisGO:00301621640.011
nitrogen compound transportGO:00717052710.011
cell activation involved in immune responseGO:00022631260.011
regionalizationGO:00030023370.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
cell adhesionGO:00071553290.011
nucleoside triphosphate metabolic processGO:00091412300.011
nucleic acid phosphodiester bond hydrolysisGO:0090305490.011
oogenesisGO:0048477560.011
maintenance of locationGO:0051235890.011
establishment of organelle localizationGO:00516561220.011
generation of precursor metabolites and energyGO:00060911030.010
cytoplasmic transportGO:00164822340.010
negative regulation of organelle organizationGO:0010639900.010
tissue remodelingGO:00487711020.010
glycosyl compound catabolic processGO:19016582060.010
multi multicellular organism processGO:00447061090.010
response to organonitrogen compoundGO:00102432460.010
negative regulation of apoptotic signaling pathwayGO:20012341040.010
ncrna processingGO:0034470260.010

Polr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:149200.019
nervous system diseaseDOID:86300.019
retinal diseaseDOID:567900.019
retinal degenerationDOID:846600.019
sensory system diseaseDOID:005015500.019
disease of anatomical entityDOID:700.019
eye diseaseDOID:561400.019
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014