IMP: Integrative Multi-species Prediction

Mus musculus

78 known processes

Oaz3

ornithine decarboxylase antizyme 3

(Aliases: AZ3,Oaz-t,Az-3)

Entrez: 53814
Ensembl: ENSMUSG00000028141
UniProtKB: Q9R109

Process Predictions
Disease Predictions

Oaz3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
amine metabolic process	GO:0009308	45	0.157
male gamete generation	GO:0048232	285	0.153
cellular amine metabolic process	GO:0044106	44	0.106
fertilization	GO:0009566	127	0.097
cellular amino acid metabolic process	GO:0006520	103	0.095
regulation of cellular ketone metabolic process	GO:0010565	66	0.093
spermatogenesis	GO:0007283	284	0.091
regulation of cellular amine metabolic process	GO:0033238	20	0.086
spermatid differentiation	GO:0048515	115	0.083
cation transport	GO:0006812	399	0.075
spermatid development	GO:0007286	108	0.073
muscle tissue development	GO:0060537	308	0.072
cell adhesion	GO:0007155	329	0.063
regulation of cellular amino acid metabolic process	GO:0006521	5	0.063
regulation of membrane potential	GO:0042391	192	0.063
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.062
germ cell development	GO:0007281	185	0.060
macromolecule catabolic process	GO:0009057	281	0.054
positive regulation of cellular amine metabolic process	GO:0033240	5	0.053
response to radiation	GO:0009314	165	0.052
negative regulation of protein metabolic process	GO:0051248	282	0.051
cellular lipid metabolic process	GO:0044255	323	0.051
forebrain development	GO:0030900	302	0.051
cilium morphogenesis	GO:0060271	102	0.045
regulation of homeostatic process	GO:0032844	182	0.045
heart morphogenesis	GO:0003007	178	0.043
cellular ketone metabolic process	GO:0042180	84	0.041
transmission of nerve impulse	GO:0019226	76	0.041
small gtpase mediated signal transduction	GO:0007264	97	0.041
membrane organization	GO:0061024	245	0.039
protein maturation	GO:0051604	176	0.039
regulation of lipid metabolic process	GO:0019216	118	0.038
regulation of kinase activity	GO:0043549	249	0.036
action potential	GO:0001508	78	0.036
negative regulation of cell proliferation	GO:0008285	296	0.035
cellular component assembly involved in morphogenesis	GO:0010927	139	0.035
neuronal action potential	GO:0019228	54	0.034
regulation of cell cycle	GO:0051726	281	0.034
striated muscle tissue development	GO:0014706	293	0.033
gland development	GO:0048732	330	0.032
regulation of systemic arterial blood pressure mediated by a chemical signal	GO:0003044	33	0.031
phospholipid metabolic process	GO:0006644	87	0.031
protein localization to organelle	GO:0033365	185	0.030
apoptotic signaling pathway	GO:0097190	306	0.030
organonitrogen compound biosynthetic process	GO:1901566	192	0.030
cell substrate adhesion	GO:0031589	130	0.029
stem cell maintenance	GO:0019827	130	0.029
regulation of transmembrane transport	GO:0034762	128	0.029
regulation of cell projection organization	GO:0031344	206	0.029
small molecule biosynthetic process	GO:0044283	132	0.029
peptidyl amino acid modification	GO:0018193	336	0.028
immune response regulating signaling pathway	GO:0002764	125	0.028
sensory perception	GO:0007600	245	0.028
cognition	GO:0050890	149	0.028
maintenance of location	GO:0051235	89	0.027
pallium development	GO:0021543	120	0.027
regulation of protein transport	GO:0051223	163	0.027
lipid transport	GO:0006869	98	0.027
organic hydroxy compound metabolic process	GO:1901615	203	0.026
neuron projection guidance	GO:0097485	141	0.026
male sex differentiation	GO:0046661	109	0.026
locomotory behavior	GO:0007626	195	0.026
regulation of translation	GO:0006417	71	0.026
response to growth factor	GO:0070848	198	0.025
blastocyst development	GO:0001824	80	0.025
posttranscriptional regulation of gene expression	GO:0010608	155	0.025
muscle contraction	GO:0006936	101	0.025
sperm egg recognition	GO:0035036	37	0.025
protein processing	GO:0016485	163	0.025
negative regulation of cellular amine metabolic process	GO:0033239	1	0.025
meiotic cell cycle process	GO:1903046	77	0.024
mapk cascade	GO:0000165	281	0.024
response to light stimulus	GO:0009416	135	0.024
microtubule based movement	GO:0007018	84	0.024
negative regulation of cellular protein metabolic process	GO:0032269	247	0.024
stem cell development	GO:0048864	219	0.024
blood circulation	GO:0008015	195	0.023
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.023
axonogenesis	GO:0007409	274	0.023
angiogenesis	GO:0001525	201	0.022
regulation of protein catabolic process	GO:0042176	108	0.022
embryonic placenta development	GO:0001892	98	0.022
response to organonitrogen compound	GO:0010243	246	0.022
positive regulation of transferase activity	GO:0051347	167	0.022
regulation of hormone levels	GO:0010817	211	0.021
purine ribonucleotide metabolic process	GO:0009150	290	0.021
cardiac chamber development	GO:0003205	108	0.021
protein modification by small protein conjugation or removal	GO:0070647	207	0.021
regulation of cell activation	GO:0050865	289	0.020
regulation of secretion by cell	GO:1903530	249	0.020
oxidation reduction process	GO:0055114	342	0.020
axon ensheathment	GO:0008366	76	0.020
anion transport	GO:0006820	177	0.020
immune effector process	GO:0002252	321	0.020
regulation of transferase activity	GO:0051338	263	0.020
single fertilization	GO:0007338	82	0.020
cytoplasmic transport	GO:0016482	234	0.020
placenta development	GO:0001890	140	0.020
multicellular organismal homeostasis	GO:0048871	164	0.020
organelle fission	GO:0048285	170	0.020
protein modification by small protein conjugation	GO:0032446	187	0.020
response to organic cyclic compound	GO:0014070	198	0.019
dna metabolic process	GO:0006259	303	0.019
chemotaxis	GO:0006935	247	0.019
circulatory system process	GO:0003013	197	0.019
reactive oxygen species metabolic process	GO:0072593	84	0.019
single organismal cell cell adhesion	GO:0016337	131	0.019
muscle cell differentiation	GO:0042692	261	0.019
protein catabolic process	GO:0030163	221	0.019
regulation of cytokine production	GO:0001817	266	0.018
lipid biosynthetic process	GO:0008610	179	0.018
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.018
cell fate commitment	GO:0045165	210	0.018
regulation of secretion	GO:0051046	274	0.018
lung development	GO:0030324	164	0.018
microtubule cytoskeleton organization	GO:0000226	157	0.018
translation	GO:0006412	93	0.018
regulation of vesicle mediated transport	GO:0060627	139	0.018
regulation of systemic arterial blood pressure	GO:0003073	61	0.018
peptidyl tyrosine phosphorylation	GO:0018108	143	0.017
cholesterol homeostasis	GO:0042632	44	0.017
regulation of anatomical structure size	GO:0090066	178	0.017
skeletal system development	GO:0001501	356	0.017
myeloid cell differentiation	GO:0030099	233	0.017
nuclear division	GO:0000280	158	0.017
protein targeting	GO:0006605	143	0.017
cellular response to growth factor stimulus	GO:0071363	197	0.017
regulation of ossification	GO:0030278	112	0.017
detection of external stimulus	GO:0009581	61	0.017
regulation of mapk cascade	GO:0043408	248	0.017
steroid metabolic process	GO:0008202	119	0.017
cellular homeostasis	GO:0019725	240	0.017
cell matrix adhesion	GO:0007160	68	0.017
regulation of response to wounding	GO:1903034	189	0.017
regulation of proteolysis	GO:0030162	164	0.016
cell cell recognition	GO:0009988	44	0.016
regulation of blood pressure	GO:0008217	93	0.016
skeletal muscle organ development	GO:0060538	163	0.016
rhythmic process	GO:0048511	174	0.016
carbohydrate derivative biosynthetic process	GO:1901137	183	0.016
glucose homeostasis	GO:0042593	128	0.016
regulation of ion transport	GO:0043269	215	0.016
cellular protein complex assembly	GO:0043623	116	0.016
sensory organ morphogenesis	GO:0090596	242	0.016
lipid localization	GO:0010876	126	0.016
regulation of intracellular transport	GO:0032386	159	0.016
organic hydroxy compound biosynthetic process	GO:1901617	77	0.015
regulation of neuron differentiation	GO:0045664	281	0.015
organic anion transport	GO:0015711	137	0.015
lipid homeostasis	GO:0055088	63	0.015
energy homeostasis	GO:0097009	15	0.015
multi multicellular organism process	GO:0044706	109	0.015
response to peptide	GO:1901652	136	0.015
synapse organization	GO:0050808	125	0.015
nucleobase containing small molecule metabolic process	GO:0055086	352	0.015
leukocyte differentiation	GO:0002521	342	0.015
negative regulation of intracellular signal transduction	GO:1902532	167	0.015
cardiac muscle tissue development	GO:0048738	130	0.015
regulation of cell motility	GO:2000145	236	0.015
epithelial cell proliferation	GO:0050673	174	0.015
homeostasis of number of cells	GO:0048872	210	0.015
microtubule based process	GO:0007017	236	0.015
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.015
exocytosis	GO:0006887	121	0.015
myelination	GO:0042552	74	0.015
erk1 and erk2 cascade	GO:0070371	77	0.015
regulation of peptide transport	GO:0090087	91	0.015
urogenital system development	GO:0001655	261	0.015
meiotic nuclear division	GO:0007126	115	0.015
cardiac muscle cell differentiation	GO:0055007	69	0.015
cytokine production	GO:0001816	319	0.015
regulation of bone remodeling	GO:0046850	28	0.015
regulation of epithelial cell proliferation	GO:0050678	141	0.014
positive regulation of protein phosphorylation	GO:0001934	242	0.014
response to peptide hormone	GO:0043434	127	0.014
multicellular organismal signaling	GO:0035637	91	0.014
maternal process involved in female pregnancy	GO:0060135	32	0.014
cellular response to organonitrogen compound	GO:0071417	145	0.014
negative regulation of cellular component organization	GO:0051129	194	0.014
binding of sperm to zona pellucida	GO:0007339	34	0.014
activation of immune response	GO:0002253	138	0.014
regionalization	GO:0003002	337	0.014
fatty acid metabolic process	GO:0006631	121	0.014
negative regulation of protein modification process	GO:0031400	163	0.014
development of primary male sexual characteristics	GO:0046546	88	0.014
protein ubiquitination	GO:0016567	171	0.014
purine containing compound metabolic process	GO:0072521	311	0.014
protein secretion	GO:0009306	111	0.014
negative regulation of molecular function	GO:0044092	258	0.014
neuromuscular process	GO:0050905	99	0.014
stem cell differentiation	GO:0048863	268	0.014
regulation of feeding behavior	GO:0060259	3	0.014
regulation of cytoplasmic transport	GO:1903649	112	0.014
male gonad development	GO:0008584	88	0.014
positive regulation of growth	GO:0045927	104	0.014
regulation of cell migration	GO:0030334	219	0.014
cilium assembly	GO:0042384	81	0.014
ear development	GO:0043583	200	0.014
response to nutrient levels	GO:0031667	109	0.014
sterol homeostasis	GO:0055092	45	0.014
glycoprotein metabolic process	GO:0009100	116	0.013
response to acid chemical	GO:0001101	111	0.013
embryonic organ morphogenesis	GO:0048562	276	0.013
regulation of leukocyte differentiation	GO:1902105	159	0.013
negative regulation of immune system process	GO:0002683	209	0.013
striated muscle contraction	GO:0006941	45	0.013
sperm motility	GO:0030317	47	0.013
ensheathment of neurons	GO:0007272	76	0.013
cytokine metabolic process	GO:0042107	71	0.013
alpha amino acid metabolic process	GO:1901605	59	0.013
regulation of tissue remodeling	GO:0034103	38	0.013
cellular response to insulin stimulus	GO:0032869	78	0.013
transmembrane transport	GO:0055085	412	0.013
ion transmembrane transport	GO:0034220	361	0.013
negative regulation of cell development	GO:0010721	169	0.013
regulation of embryonic development	GO:0045995	71	0.013
regulation of protein stability	GO:0031647	52	0.013
circadian rhythm	GO:0007623	114	0.013
development of primary female sexual characteristics	GO:0046545	73	0.013
fat soluble vitamin biosynthetic process	GO:0042362	4	0.013
endocytosis	GO:0006897	168	0.013
cellular chemical homeostasis	GO:0055082	215	0.013
regulation of organelle organization	GO:0033043	289	0.013
innate immune response	GO:0045087	157	0.013
glycerolipid metabolic process	GO:0046486	122	0.013
establishment of protein localization to organelle	GO:0072594	118	0.012
striated muscle cell development	GO:0055002	125	0.012
cellular response to peptide hormone stimulus	GO:0071375	92	0.012
renal system process involved in regulation of blood volume	GO:0001977	4	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
glycerophospholipid metabolic process	GO:0006650	71	0.012
monocarboxylic acid metabolic process	GO:0032787	191	0.012
central nervous system neuron differentiation	GO:0021953	162	0.012
adult locomotory behavior	GO:0008344	91	0.012
synaptic transmission	GO:0007268	329	0.012
negative regulation of nervous system development	GO:0051961	156	0.012
anatomical structure homeostasis	GO:0060249	145	0.012
somite development	GO:0061053	81	0.012
regulation of system process	GO:0044057	200	0.012
compound eye development	GO:0048749	1	0.012
multicellular organism growth	GO:0035264	161	0.012
response to temperature stimulus	GO:0009266	55	0.012
reactive nitrogen species metabolic process	GO:2001057	0	0.012
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.012
immune response activating signal transduction	GO:0002757	116	0.012
cardiac chamber morphogenesis	GO:0003206	93	0.012
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.012
ras protein signal transduction	GO:0007265	77	0.012
regulation of lymphocyte activation	GO:0051249	240	0.012
carboxylic acid biosynthetic process	GO:0046394	86	0.012
muscle system process	GO:0003012	141	0.012
epithelial cell development	GO:0002064	159	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
leukocyte mediated immunity	GO:0002443	174	0.011
organ growth	GO:0035265	117	0.011
septum primum development	GO:0003284	4	0.011
response to transforming growth factor beta	GO:0071559	88	0.011
insulin secretion	GO:0030073	89	0.011
cellular response to cytokine stimulus	GO:0071345	189	0.011
regulation of cell growth	GO:0001558	91	0.011
glial cell differentiation	GO:0010001	131	0.011
carbohydrate derivative catabolic process	GO:1901136	231	0.011
negative regulation of protein phosphorylation	GO:0001933	126	0.011
developmental growth involved in morphogenesis	GO:0060560	138	0.011
organelle assembly	GO:0070925	177	0.011
digestive tract development	GO:0048565	190	0.011
cell growth	GO:0016049	130	0.011
regulation of ion transmembrane transport	GO:0034765	119	0.011
regulation of cell cycle process	GO:0010564	160	0.011
myotube differentiation	GO:0014902	105	0.011
axon guidance	GO:0007411	141	0.011
positive regulation of nuclear division	GO:0051785	27	0.011
positive regulation of organelle organization	GO:0010638	128	0.011
positive regulation of neuron projection regeneration	GO:0070572	2	0.011
camera type eye development	GO:0043010	266	0.011
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.011
establishment of vesicle localization	GO:0051650	81	0.011
meiotic cell cycle	GO:0051321	122	0.011
leukocyte proliferation	GO:0070661	172	0.011
protein localization to membrane	GO:0072657	108	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
regulation of endopeptidase activity	GO:0052548	89	0.011
midgut development	GO:0007494	4	0.011
hormone metabolic process	GO:0042445	86	0.011
positive regulation of cell development	GO:0010720	237	0.011
negative regulation of feeding behavior	GO:2000252	1	0.010
regulation of body fluid levels	GO:0050878	162	0.010
muscle cell development	GO:0055001	133	0.010
actin filament based movement	GO:0030048	23	0.010
myeloid cell homeostasis	GO:0002262	114	0.010
dibenzo p dioxin metabolic process	GO:0018894	1	0.010
neural tube formation	GO:0001841	108	0.010
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.010
negative regulation of phosphorylation	GO:0042326	166	0.010
gene silencing	GO:0016458	38	0.010
feeding behavior	GO:0007631	62	0.010
positive regulation of intracellular transport	GO:0032388	70	0.010
tissue homeostasis	GO:0001894	115	0.010
regulation of antimicrobial humoral response	GO:0002759	3	0.010
cellular response to organic cyclic compound	GO:0071407	87	0.010
regulation of systemic arterial blood pressure by renin angiotensin	GO:0003081	20	0.010
regulation of peptide secretion	GO:0002791	77	0.010
regulation of cell substrate adhesion	GO:0010810	73	0.010
cardiocyte differentiation	GO:0035051	87	0.010
mitotic cell cycle	GO:0000278	195	0.010
olfactory learning	GO:0008355	2	0.010

Oaz3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.023
disease of anatomical entity	DOID:7	0.023
central nervous system disease	DOID:331	0.023
disease of metabolism	DOID:0014667	0.017
heart disease	DOID:114	0.017
cardiovascular system disease	DOID:1287	0.017
musculoskeletal system disease	DOID:17	0.017
cancer	DOID:162	0.014
organ system cancer	DOID:0050686	0.014
disease of cellular proliferation	DOID:14566	0.014
inherited metabolic disorder	DOID:655	0.013

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network