Mus musculus

34 known processes

Dcn

decorin

(Aliases: PG40,PGII,DC,SLRR1B,PGS2,DSPG2,mDcn)

Dcn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of tooth mineralizationGO:007017020.896
Mouse
chondroitin sulfate metabolic processGO:0030204170.863
negative regulation of tooth mineralizationGO:007017110.686
Mouse
negative regulation of odontogenesisGO:004248330.634
Mouse
peptide cross linkingGO:0018149100.552
peptide cross linking via chondroitin 4 sulfate glycosaminoglycanGO:001980080.461
cellular response to growth factor stimulusGO:00713631970.431
Mouse
negative regulation of protein activation cascadeGO:200025830.421
negative regulation of complement activationGO:004591630.420
peptidyl serine modificationGO:0018209830.414
extracellular structure organizationGO:00430621480.387
proteoglycan metabolic processGO:0006029380.323
immune effector processGO:00022523210.265
response to growth factorGO:00708481980.258
Mouse
chondroitin sulfate proteoglycan metabolic processGO:0050654200.239
protein maturationGO:00516041760.230
camera type eye developmentGO:00430102660.230
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.225
Mouse
protein processingGO:00164851630.214
embryonic organ morphogenesisGO:00485622760.200
peptidyl amino acid modificationGO:00181933360.187
tooth mineralizationGO:003450590.178
Mouse
negative regulation of hydrolase activityGO:0051346710.173
glycoprotein metabolic processGO:00091001160.165
glycosaminoglycan metabolic processGO:0030203340.162
regulation of complement activationGO:003044970.157
regulation of cellular response to growth factor stimulusGO:0090287820.153
Mouse
regulation of cellular ketone metabolic processGO:0010565660.151
aminoglycan metabolic processGO:0006022340.146
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.144
Mouse
cation transportGO:00068123990.135
muscle tissue developmentGO:00605373080.135
Rat
regulation of apoptotic signaling pathwayGO:20012331970.132
extracellular matrix organizationGO:00301981470.125
regulation of organ morphogenesisGO:20000271440.125
Mouse
regulation of cell adhesionGO:00301551540.125
negative regulation of cellular protein metabolic processGO:00322692470.117
regulation of cellular amine metabolic processGO:0033238200.114
regulation of protein maturationGO:1903317960.113
negative regulation of biomineral tissue developmentGO:0070168110.113
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560880.111
Mouse
response to organic cyclic compoundGO:00140701980.111
transforming growth factor beta receptor signaling pathwayGO:0007179710.110
Mouse
respiratory system developmentGO:00605411900.110
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.105
Mouse
mucopolysaccharide metabolic processGO:1903510250.104
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.102
Mouse
regulation of blood pressureGO:0008217930.101
activation of immune responseGO:00022531380.096
regulation of peptidase activityGO:0052547960.094
response to molecule of bacterial originGO:00022371430.093
Rat
cartilage developmentGO:00512161400.093
Zebrafish
negative regulation of molecular functionGO:00440922580.093
connective tissue developmentGO:00614481790.092
Zebrafish
cellular lipid metabolic processGO:00442553230.089
sulfur compound metabolic processGO:00067901000.086
negative regulation of protein metabolic processGO:00512482820.084
response to organonitrogen compoundGO:00102432460.084
response to transforming growth factor betaGO:0071559880.083
Mouse
regulation of response to woundingGO:19030341890.081
epidermis developmentGO:00085441870.081
biomineral tissue developmentGO:0031214640.078
Mouse
cellular amine metabolic processGO:0044106440.076
positive regulation of chemotaxisGO:0050921380.076
cell substrate adhesionGO:00315891300.076
regulation of protein processingGO:0070613960.075
embryonic camera type eye developmentGO:0031076360.075
small gtpase mediated signal transductionGO:0007264970.074
angiogenesisGO:00015252010.071
cellular response to peptideGO:1901653920.071
negative regulation of proteolysisGO:0045861740.067
negative regulation of protein maturationGO:1903318790.066
negative regulation of phospholipase activityGO:001051940.065
blood circulationGO:00080151950.065
regulation of endopeptidase activityGO:0052548890.065
regulation of protein activation cascadeGO:200025770.064
gland developmentGO:00487323300.063
blood vessel morphogenesisGO:00485142850.063
negative regulation of cellular response to growth factor stimulusGO:0090288460.063
Mouse
oxidation reduction processGO:00551143420.062
tissue remodelingGO:00487711020.061
amine metabolic processGO:0009308450.060
cell adhesionGO:00071553290.055
positive regulation of cellular amine metabolic processGO:003324050.055
divalent metal ion transportGO:00708381720.055
circulatory system processGO:00030131970.053
regulation of proteolysisGO:00301621640.049
cellular response to organonitrogen compoundGO:00714171450.049
negative regulation of phosphorus metabolic processGO:00105631840.049
transmembrane transportGO:00550854120.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
positive regulation of nervous system developmentGO:00519622210.049
mapk cascadeGO:00001652810.049
regulation of inflammatory responseGO:00507271470.048
extrinsic apoptotic signaling pathwayGO:00971911260.047
positive regulation of behaviorGO:0048520400.047
response to acid chemicalGO:00011011110.046
negative regulation of cell proliferationGO:00082852960.046
inorganic ion transmembrane transportGO:00986602340.046
cellular ketone metabolic processGO:0042180840.045
response to lipopolysaccharideGO:00324961280.045
Rat
regulation of odontogenesisGO:0042481180.045
Mouse
negative regulation of protein processingGO:0010955790.045
skeletal system developmentGO:00015013560.045
Zebrafish
negative regulation of peptidase activityGO:0010466460.042
ossificationGO:00015032160.042
response to oxidative stressGO:00069791230.041
skin developmentGO:00435882200.041
response to peptideGO:19016521360.040
respiratory tube developmentGO:00303231670.040
skeletal system morphogenesisGO:00487052030.040
cytokine productionGO:00018163190.040
regulation of epithelial cell proliferationGO:00506781410.040
regulation of hormone levelsGO:00108172110.039
regulation of cell growthGO:0001558910.039
regulation of mapk cascadeGO:00434082480.039
regulation of cell projection organizationGO:00313442060.038
forebrain developmentGO:00309003020.037
nucleoside phosphate metabolic processGO:00067533380.037
cellular nitrogen compound catabolic processGO:00442702800.037
digestive system developmentGO:00551232000.036
positive regulation of programmed cell deathGO:00430682180.036
single organism cell adhesionGO:00986021560.036
complement activationGO:0006956160.036
protein localization to plasma membraneGO:0072659570.036
rho protein signal transductionGO:0007266320.036
odontogenesisGO:0042476780.036
Mouse
glycerolipid metabolic processGO:00464861220.035
response to inorganic substanceGO:0010035960.035
vascular process in circulatory systemGO:0003018620.035
developmental growth involved in morphogenesisGO:00605601380.034
Zebrafish
ras protein signal transductionGO:0007265770.034
positive regulation of protein phosphorylationGO:00019342420.034
cellular macromolecule catabolic processGO:00442652060.034
type b pancreatic cell proliferationGO:0044342100.034
fat cell differentiationGO:00454441600.033
positive regulation of protein modification processGO:00314012990.033
regulation of ion transportGO:00432692150.033
regulation of reproductive processGO:2000241660.033
regulation of neurotransmitter levelsGO:0001505870.032
regulation of biomineral tissue developmentGO:0070167330.032
Mouse
carbohydrate metabolic processGO:00059752300.031
regulation of fat cell differentiationGO:0045598810.030
limb morphogenesisGO:00351081490.030
lymphocyte mediated immunityGO:00024491390.030
mitotic cell cycle processGO:19030471590.030
negative regulation of endopeptidase activityGO:0010951440.030
lipid catabolic processGO:0016042690.030
aromatic compound catabolic processGO:00194392860.029
multicellular organismal metabolic processGO:0044236280.029
urogenital system developmentGO:00016552610.029
Rat
carbohydrate homeostasisGO:00335001280.029
regulation of body fluid levelsGO:00508781620.028
axonogenesisGO:00074092740.028
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356880.028
regulation of protein kinase activityGO:00458592320.028
canonical wnt signaling pathwayGO:00600701300.028
regulation of neuron differentiationGO:00456642810.028
positive regulation of hydrolase activityGO:00513451480.028
heart morphogenesisGO:00030071780.027
regulation of cell migrationGO:00303342190.027
regulation of ras protein signal transductionGO:00465781140.027
positive regulation of cell developmentGO:00107202370.027
regulation of membrane potentialGO:00423911920.027
brown fat cell differentiationGO:0050873360.027
regulation of cellular amino acid metabolic processGO:000652150.027
epithelial cell proliferationGO:00506731740.027
neutrophil chemotaxisGO:0030593360.027
regulation of hydrolase activityGO:00513362460.027
regulation of kinase activityGO:00435492490.026
inorganic cation transmembrane transportGO:00986622070.026
apoptotic signaling pathwayGO:00971903060.026
positive regulation of growthGO:00459271040.026
regulation of cytokine productionGO:00018172660.025
kidney developmentGO:00018222130.025
Rat
nitrogen compound transportGO:00717052710.025
negative regulation of ossificationGO:0030279490.025
regulation of systemic arterial blood pressureGO:0003073610.025
regulation of removal of superoxide radicalsGO:200012140.025
acetylcholine transportGO:001587020.025
chemotaxisGO:00069352470.025
macromolecule catabolic processGO:00090572810.025
endomembrane system organizationGO:00102561470.024
cellular response to dna damage stimulusGO:00069742070.024
negative regulation of phosphorylationGO:00423261660.024
lipid localizationGO:00108761260.024
negative regulation of apoptotic signaling pathwayGO:20012341040.024
negative regulation of cell adhesionGO:0007162450.024
neutrophil migrationGO:1990266370.024
proteolysis involved in cellular protein catabolic processGO:00516031470.024
nuclear transportGO:00511691390.023
regulation of reactive oxygen species biosynthetic processGO:190342620.023
regulation of cell motilityGO:20001452360.023
inflammatory responseGO:00069542440.023
neutral lipid metabolic processGO:0006638570.023
negative regulation of protein phosphorylationGO:00019331260.023
regulation of protein stabilityGO:0031647520.022
long chain fatty acid importGO:004453920.022
forelimb morphogenesisGO:0035136400.022
anatomical structure homeostasisGO:00602491450.022
cardiac muscle tissue developmentGO:00487381300.022
negative regulation of blood vessel morphogenesisGO:2000181250.021
negative regulation of protein modification processGO:00314001630.021
positive regulation of cell growthGO:0030307330.021
detection of chemical stimulus involved in sensory perception of tasteGO:005091230.021
cilium morphogenesisGO:00602711020.021
organic hydroxy compound metabolic processGO:19016152030.021
response to steroid hormoneGO:0048545560.021
regulation of vesicle mediated transportGO:00606271390.021
response to extracellular stimulusGO:00099911270.021
negative regulation of immune system processGO:00026832090.020
response to radiationGO:00093141650.020
endocytosisGO:00068971680.020
heterocycle catabolic processGO:00467002800.020
nucleobase containing small molecule metabolic processGO:00550863520.020
tissue homeostasisGO:00018941150.020
cellular response to hormone stimulusGO:00328701500.020
positive regulation of kinase activityGO:00336741550.020
cellular divalent inorganic cation homeostasisGO:00725031270.020
anion transportGO:00068201770.020
cellular protein catabolic processGO:00442571550.019
engulfment of apoptotic cellGO:004365230.019
regulation of organelle organizationGO:00330432890.019
cation transmembrane transportGO:00986552660.019
lipid transportGO:0006869980.019
cell matrix adhesionGO:0007160680.019
regulation of transferase activityGO:00513382630.019
divalent inorganic cation transportGO:00725111780.019
dna metabolic processGO:00062593030.019
insulin metabolic processGO:190114230.019
negative regulation of cell cycleGO:00457861230.019
regulation of cell cycleGO:00517262810.019
microtubule cytoskeleton organizationGO:00002261570.019
regulation of peptidyl tyrosine phosphorylationGO:0050730930.019
muscle cell proliferationGO:0033002520.019
sensory perception of mechanical stimulusGO:00509541070.019
regulation of receptor activityGO:0010469410.018
regulation of cell cycle processGO:00105641600.018
regulation of neutrophil migrationGO:1902622140.018
regulation of protein bindingGO:0043393600.018
regulation of cellular carbohydrate metabolic processGO:0010675750.018
cellular ion homeostasisGO:00068731650.018
positive regulation of cytokine productionGO:00018191740.018
isoprenoid metabolic processGO:0006720290.018
response to insulinGO:00328681000.018
cellular response to cytokine stimulusGO:00713451890.018
wound healingGO:00420601570.018
Rat
regulation of neuron projection developmentGO:00109751690.018
regulation of cell sizeGO:0008361720.018
inner ear morphogenesisGO:00424721010.017
cellular homeostasisGO:00197252400.017
positive regulation of cardiac muscle contractionGO:006045220.017
positive regulation of cell migrationGO:00303351090.017
actin cytoskeleton organizationGO:00300362200.017
cellular metal ion homeostasisGO:00068751510.017
response to peptide hormoneGO:00434341270.017
regulation of neutrophil chemotaxisGO:0090022140.017
regulation of system processGO:00440572000.016
transmission of nerve impulseGO:0019226760.016
granulocyte migrationGO:0097530430.016
ion transmembrane transportGO:00342203610.016
multicellular organism growthGO:00352641610.016
reactive oxygen species metabolic processGO:0072593840.016
neuromuscular process controlling balanceGO:0050885590.016
calcium ion homeostasisGO:00550741270.016
regulation of angiogenesisGO:0045765810.016
mitotic cell cycleGO:00002781950.016
homeostasis of number of cellsGO:00488722100.016
regulation of extent of cell growthGO:0061387520.016
positive regulation of apoptotic processGO:00430652170.016
i kappab kinase nf kappab signalingGO:0007249850.016
organelle fissionGO:00482851700.016
cerebral cortex developmentGO:0021987860.016
regulation of secretionGO:00510462740.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.016
posttranscriptional regulation of gene expressionGO:00106081550.016
hair follicle morphogenesisGO:0031069290.016
cellular amino acid metabolic processGO:00065201030.015
glucose metabolic processGO:0006006920.015
fatty acid metabolic processGO:00066311210.015
cellular chemical homeostasisGO:00550822150.015
positive regulation of neuron differentiationGO:00456661410.015
metencephalon developmentGO:0022037890.015
diterpenoid metabolic processGO:0016101240.015
gliogenesisGO:00420631410.015
regulation of reactive oxygen species metabolic processGO:2000377400.015
cytoplasmic transportGO:00164822340.015
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.015
muscle system processGO:00030121410.015
regulation of ion transmembrane transportGO:00347651190.015
nucleoside triphosphate metabolic processGO:00091412300.015
divalent inorganic cation homeostasisGO:00725071380.015
detection of abiotic stimulusGO:0009582600.015
regulation of anatomical structure sizeGO:00900661780.015
cellular response to acid chemicalGO:0071229680.015
cellular response to molecule of bacterial originGO:0071219830.015
telencephalon developmentGO:00215371860.015
epithelial tube morphogenesisGO:00605623030.015
cytokine mediated signaling pathwayGO:00192211150.015
organic cyclic compound catabolic processGO:19013612950.015
embryonic skeletal system developmentGO:00487061200.015
trabecula formationGO:0060343240.015
regulation of protein serine threonine kinase activityGO:00719001570.015
regulation of canonical wnt signaling pathwayGO:0060828820.014
positive regulation of neuron projection developmentGO:0010976790.014
cellular response to lipidGO:00713961450.014
innate immune responseGO:00450871570.014
regulation of vasculature developmentGO:1901342880.014
neuromuscular processGO:0050905990.014
negative regulation of cellular component organizationGO:00511291940.014
compound eye developmentGO:004874910.014
renal system processGO:0003014480.014
myeloid cell differentiationGO:00300992330.014
triglyceride metabolic processGO:0006641510.014
cellular lipid catabolic processGO:0044242520.014
regulation of systemic arterial blood pressure mediated by a chemical signalGO:0003044330.014
muscle hypertrophyGO:0014896240.014
sodium ion transportGO:0006814730.014
regulation of cell substrate adhesionGO:0010810730.014
regulation of phospholipid biosynthetic processGO:007107130.014
branching morphogenesis of an epithelial tubeGO:00487541590.014
regulation of cellular catabolic processGO:00313292420.014
developmental maturationGO:00217001930.014
regulation of lymphocyte activationGO:00512492400.014
hormone metabolic processGO:0042445860.014
protein localization to membraneGO:00726571080.014
collagen fibril organizationGO:0030199320.014
regulation of acute inflammatory responseGO:0002673270.014
calcium ion transportGO:00068161590.014
cell junction organizationGO:0034330770.013
regulation of establishment of protein localizationGO:00702011810.013
negative regulation of kinase activityGO:0033673810.013
membrane organizationGO:00610242450.013
sensory organ morphogenesisGO:00905962420.013
positive regulation of secretionGO:00510471300.013
morphogenesis of embryonic epitheliumGO:00163311590.013
positive regulation of cell substrate adhesionGO:0010811470.013
lateral line system developmentGO:004892510.013
negative regulation of angiogenesisGO:0016525250.013
nucleotide catabolic processGO:00091662170.013
embryonic eye morphogenesisGO:0048048290.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
striated muscle tissue developmentGO:00147062930.013
Rat
regulation of muscle system processGO:0090257800.013
sequestering of metal ionGO:0051238190.013
palate developmentGO:0060021760.013
response to purine containing compoundGO:0014074280.013
regulation of transmembrane transportGO:00347621280.013
regulation of multicellular organismal metabolic processGO:0044246140.013
regulation of macrophage migration inhibitory factor signaling pathwayGO:200044610.013
small molecule biosynthetic processGO:00442831320.013
regulation of cellular response to oxidative stressGO:1900407190.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
phospholipid metabolic processGO:0006644870.013
plasma membrane organizationGO:0007009900.013
regulation of defense responseGO:00313472330.013
neuron projection guidanceGO:00974851410.013
regulation of antimicrobial peptide productionGO:000278410.012
sodium ion exportGO:007143620.012
bone developmentGO:00603481200.012
lung morphogenesisGO:0060425500.012
endocrine processGO:0050886390.012
cellular potassium ion transportGO:0071804430.012
lung developmentGO:00303241640.012
regulation of systemic arterial blood pressure by hormoneGO:0001990250.012
fibril organizationGO:009743520.012
hexose metabolic processGO:0019318980.012
cellular response to organic cyclic compoundGO:0071407870.012
cation homeostasisGO:00550802120.012
regulation of striated muscle cell differentiationGO:0051153810.012
heart growthGO:0060419450.012
regulation of metal ion transportGO:00109591060.012
terpenoid metabolic processGO:0006721250.012
digestive tract morphogenesisGO:00485461470.012
ear morphogenesisGO:00424711180.012
ear developmentGO:00435832000.012
response to nutrient levelsGO:00316671090.012
regulation of intracellular protein transportGO:0033157820.012
protein catabolic processGO:00301632210.012
sensory perception of light stimulusGO:0050953540.012
nucleotide metabolic processGO:00091173320.012
skin morphogenesisGO:0043589380.012
retinoid metabolic processGO:0001523240.012
sodium ion transmembrane transportGO:0035725490.012
positive regulation of angiogenesisGO:0045766460.012
purine nucleoside catabolic processGO:00061522050.012
peptidyl tyrosine modificationGO:00182121450.012
negative regulation of intracellular signal transductionGO:19025321670.012
t cell activationGO:00421102890.011
positive regulation of cell projection organizationGO:0031346950.011
ribonucleotide metabolic processGO:00092592910.011
cell growthGO:00160491300.011
response to amino acidGO:0043200370.011
reactive oxygen species biosynthetic processGO:190340980.011
negative regulation of transferase activityGO:0051348850.011
organic hydroxy compound biosynthetic processGO:1901617770.011
purine containing compound metabolic processGO:00725213110.011
cellular component assembly involved in morphogenesisGO:00109271390.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.011
Mouse
jnk cascadeGO:0007254720.011
nucleoside phosphate catabolic processGO:19012922220.011
guanosine containing compound catabolic processGO:19010691440.011
positive regulation of integrin mediated signaling pathwayGO:200104650.011
negative regulation of phosphate metabolic processGO:00459361840.011
response to organophosphorusGO:0046683220.011
acylglycerol metabolic processGO:0006639550.011
organic anion transportGO:00157111370.011
positive regulation of granulocyte chemotaxisGO:0071624120.011
negative regulation of secretionGO:0051048610.011
protein localization to organelleGO:00333651850.011
insulin processingGO:003007020.011
oxygen metabolic processGO:007259240.011
wnt signaling pathwayGO:00160551880.011
regulation of lipoprotein metabolic processGO:005074640.011
regulation of granulocyte chemotaxisGO:0071622170.011
retina development in camera type eyeGO:00600411190.011
regulation of rho protein signal transductionGO:0035023710.011
response to reactive oxygen speciesGO:0000302560.011
kidney mesenchyme morphogenesisGO:007213140.011
regulation of secretion by cellGO:19035302490.011
peptide transportGO:00158331330.011
regulation of wnt signaling pathwayGO:00301111230.011
physiological cardiac muscle hypertrophyGO:000330130.011
purine ribonucleoside triphosphate metabolic processGO:00092052200.011
lipid biosynthetic processGO:00086101790.011
t cell mediated cytotoxicityGO:0001913260.011
sequestering of calcium ionGO:0051208180.011
purine ribonucleotide metabolic processGO:00091502900.011
mitochondrion organizationGO:00070051340.010
regulation of antibacterial peptide productionGO:000278610.010
nucleic acid phosphodiester bond hydrolysisGO:0090305490.010
cellular response to abiotic stimulusGO:0071214560.010
ribonucleoside triphosphate metabolic processGO:00091992200.010
fertilizationGO:00095661270.010
negative regulation of immune effector processGO:0002698550.010
regulation of lipid metabolic processGO:00192161180.010
cellular calcium ion homeostasisGO:00068741190.010
defense response to other organismGO:00985421970.010
cellular response to insulin stimulusGO:0032869780.010
negative regulation of mapk cascadeGO:0043409650.010
muscle tissue morphogenesisGO:0060415530.010
ribose phosphate metabolic processGO:00196932910.010
lateral inhibitionGO:004633110.010

Dcn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.044
myopathyDOID:42300.044
muscular diseaseDOID:008000000.044
disease of anatomical entityDOID:700.044
musculoskeletal system diseaseDOID:1700.044
normocytic anemiaDOID:72000.039
immune system diseaseDOID:291400.039
hematopoietic system diseaseDOID:7400.039
anemiaDOID:235500.039
hemolytic uremic syndromeDOID:1255400.039
hemolytic anemiaDOID:58300.039
bone development diseaseDOID:008000600.033
bone diseaseDOID:008000100.033
connective tissue diseaseDOID:6500.033
acquired metabolic diseaseDOID:006015800.027
disease of metabolismDOID:001466700.027
nervous system diseaseDOID:86300.019
integumentary system diseaseDOID:1600.017
eye and adnexa diseaseDOID:149200.016
sensory system diseaseDOID:005015500.016
eye diseaseDOID:561400.016
collagen diseaseDOID:85400.015
amyloidosisDOID:912000.011
inherited metabolic disorderDOID:65500.011